GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
CREM | hg38_v1_chr10_+_35175586_35175620 | 0.17 | 1.1e-02 | Click! |
CREB5 | hg38_v1_chr7_+_28412511_28412536, hg38_v1_chr7_+_28685968_28685991 | 0.11 | 9.5e-02 | Click! |
JUNB | hg38_v1_chr19_+_12791470_12791494 | -0.03 | 6.7e-01 | Click! |
Promoter | Score | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr22_-_43862480 Show fit | 73.63 |
ENST00000330884.9
|
sulfotransferase family 4A member 1 |
|
chr14_-_103522696 Show fit | 54.35 |
ENST00000553878.5
ENST00000348956.7 ENST00000557530.1 |
creatine kinase B |
|
chrX_-_13938378 Show fit | 47.74 |
ENST00000398361.7
|
glycoprotein M6B |
|
chr2_+_148875214 Show fit | 47.44 |
ENST00000435030.6
ENST00000677891.1 ENST00000677843.1 ENST00000678056.1 ENST00000677280.1 |
kinesin family member 5C |
|
chrX_-_13938618 Show fit | 44.24 |
ENST00000454189.6
|
glycoprotein M6B |
|
chr8_-_27258414 Show fit | 42.93 |
ENST00000523048.5
|
stathmin 4 |
|
chr20_+_10218808 Show fit | 41.99 |
ENST00000254976.7
ENST00000304886.6 |
synaptosome associated protein 25 |
|
chr20_-_3173516 Show fit | 41.44 |
ENST00000360342.7
ENST00000645462.1 ENST00000337576.7 |
leucine zipper tumor suppressor family member 3 |
|
chr6_-_46325641 Show fit | 41.03 |
ENST00000330430.10
ENST00000405162.2 |
regulator of calcineurin 2 |
|
chrX_-_47619850 Show fit | 40.78 |
ENST00000295987.13
ENST00000340666.5 |
synapsin I |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
10.9 | 130.7 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
1.8 | 74.9 | GO:0007019 | microtubule depolymerization(GO:0007019) |
2.4 | 73.6 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
1.5 | 58.0 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
0.8 | 55.2 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
9.1 | 54.4 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
1.0 | 50.0 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
2.2 | 46.7 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
2.3 | 40.8 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
6.3 | 38.0 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 171.1 | GO:0060076 | excitatory synapse(GO:0060076) |
0.6 | 95.7 | GO:0030426 | growth cone(GO:0030426) |
0.7 | 72.2 | GO:0014704 | intercalated disc(GO:0014704) |
0.2 | 71.8 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.9 | 66.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 51.8 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
3.4 | 47.4 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.5 | 45.2 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
10.5 | 42.0 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
0.3 | 41.6 | GO:0043204 | perikaryon(GO:0043204) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.1 | 73.6 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
0.4 | 60.1 | GO:0005179 | hormone activity(GO:0005179) |
2.2 | 54.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
3.4 | 54.6 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
6.8 | 54.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.2 | 49.7 | GO:0015631 | tubulin binding(GO:0015631) |
0.9 | 49.5 | GO:0030507 | spectrin binding(GO:0030507) |
0.5 | 44.3 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.2 | 43.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
1.3 | 43.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 76.7 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
2.1 | 58.7 | PID S1P S1P4 PATHWAY | S1P4 pathway |
0.8 | 34.7 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
1.2 | 29.8 | PID S1P S1P3 PATHWAY | S1P3 pathway |
0.8 | 29.4 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.6 | 24.4 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.4 | 24.1 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.1 | 23.7 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.5 | 20.1 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
0.3 | 18.9 | PID RHOA PATHWAY | RhoA signaling pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 81.8 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
3.2 | 73.6 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
1.6 | 66.6 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
0.2 | 63.2 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
1.3 | 34.7 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.9 | 33.1 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.7 | 31.6 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.2 | 31.3 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
1.3 | 28.0 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.1 | 27.8 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |