GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
E2F2 Links Ensembl NCBI GeneCards UniProt	ENSG00000007968.7	E2F2
E2F5 Links Ensembl NCBI GeneCards UniProt	ENSG00000133740.11	E2F5

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2F2	hg38_v1_chr1_-_23531206_23531241	-0.44	9.7e-12	Click!
E2F5	hg38_v1_chr8_+_85187650_85187685	0.41	4.6e-10	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr2_+_10123171 Show fit	204.86	ENST00000615152.5	RRM2 Links Ensembl NCBI GeneCards UniProt Show fit	ribonucleotide reductase regulatory subunit M2
chr2_-_135876382 Show fit	124.17	ENST00000264156.3	MCM6 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 6
chr10_+_60778331 Show fit	123.61	ENST00000519078.6 ENST00000316629.8 ENST00000395284.8	CDK1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 1
chr7_-_100101333 Show fit	117.20	ENST00000303887.10	MCM7 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 7
chr10_+_60778490 Show fit	116.06	ENST00000448257.6 ENST00000614696.4	CDK1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 1
chr15_-_64381431 Show fit	105.89	ENST00000558008.3 ENST00000300035.9 ENST00000559519.5 ENST00000380258.6	PCLAF Links Ensembl NCBI GeneCards UniProt Show fit	PCNA clamp associated factor
chr6_+_24775413 Show fit	99.37	ENST00000378054.6 ENST00000620958.4 ENST00000476555.5	GMNN Links Ensembl NCBI GeneCards UniProt Show fit	geminin DNA replication inhibitor
chr6_-_52284677 Show fit	96.97	ENST00000596288.7 ENST00000616552.4 ENST00000229854.12 ENST00000419835.8	MCM3 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 3
chr6_+_24774925 Show fit	94.43	ENST00000356509.7 ENST00000230056.8	GMNN Links Ensembl NCBI GeneCards UniProt Show fit	geminin DNA replication inhibitor
chr20_+_25407657 Show fit	93.15	ENST00000262460.5	GINS1 Links Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 1
chr3_+_127598400 Show fit	89.50	ENST00000265056.12	MCM2 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 2
chr1_-_25906457 Show fit	85.49	ENST00000426559.6	STMN1 Links Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr19_-_10194898 Show fit	84.83	ENST00000359526.9 ENST00000679103.1 ENST00000676610.1 ENST00000678804.1 ENST00000679313.1 ENST00000677946.1	DNMT1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA methyltransferase 1
chr8_-_123396412 Show fit	81.93	ENST00000287394.10	ATAD2 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase family AAA domain containing 2
chr10_-_73247241 Show fit	79.09	ENST00000372950.6	DNAJC9 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C9
chr7_+_26201705 Show fit	75.02	ENST00000396386.7 ENST00000456948.5 ENST00000409747.5	CBX3 Links Ensembl NCBI GeneCards UniProt Show fit	chromobox 3
chr2_+_10122730 Show fit	72.63	ENST00000304567.10	RRM2 Links Ensembl NCBI GeneCards UniProt Show fit	ribonucleotide reductase regulatory subunit M2
chr7_-_100101915 Show fit	72.61	ENST00000621318.4 ENST00000343023.10	MCM7 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 7
chr6_-_18264475 Show fit	71.75	ENST00000515742.2 ENST00000651624.1 ENST00000507591.2 ENST00000652689.1 ENST00000244776.11 ENST00000503715.5	DEK Links Ensembl NCBI GeneCards UniProt Show fit	DEK proto-oncogene
chr5_-_80654956 Show fit	55.69	ENST00000439211.7	DHFR Links Ensembl NCBI GeneCards UniProt Show fit	dihydrofolate reductase
chr5_-_80654552 Show fit	55.61	ENST00000511032.5 ENST00000504396.1 ENST00000505337.5	DHFR Links Ensembl NCBI GeneCards UniProt Show fit	dihydrofolate reductase
chr11_+_65041203 Show fit	52.90	ENST00000652489.1 ENST00000674184.1	SAC3D1 Links Ensembl NCBI GeneCards UniProt Show fit	SAC3 domain containing 1
chr1_-_25906411 Show fit	51.38	ENST00000455785.7	STMN1 Links Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr18_+_21612274 Show fit	50.95	ENST00000579618.1 ENST00000300413.10 ENST00000582475.1	SNRPD1 Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein D1 polypeptide
chr14_-_49688201 Show fit	50.32	ENST00000553805.2 ENST00000554396.5 ENST00000216367.10	POLE2 Links Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase epsilon 2, accessory subunit
chr15_-_66356672 Show fit	50.22	ENST00000261881.9	TIPIN Links Ensembl NCBI GeneCards UniProt Show fit	TIMELESS interacting protein
chr11_+_65040895 Show fit	49.17	ENST00000531072.1 ENST00000398846.6	SAC3D1 Links Ensembl NCBI GeneCards UniProt Show fit	SAC3 domain containing 1
chr1_+_212035717 Show fit	48.72	ENST00000366991.5	DTL Links Ensembl NCBI GeneCards UniProt Show fit	denticleless E3 ubiquitin protein ligase homolog
chr2_-_46941710 Show fit	46.42	ENST00000409207.5	MCFD2 Links Ensembl NCBI GeneCards UniProt Show fit	multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr22_+_35400115 Show fit	45.90	ENST00000382011.9 ENST00000216122.9 ENST00000416905.1	MCM5 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 5
chr7_-_158704740 Show fit	45.51	ENST00000409339.3 ENST00000356309.8 ENST00000409423.5	NCAPG2 Links Ensembl NCBI GeneCards UniProt Show fit	non-SMC condensin II complex subunit G2
chr7_-_26201301 Show fit	42.72	ENST00000608362.2 ENST00000676749.1 ENST00000677839.1	HNRNPA2B1 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein A2/B1
chr5_+_36151989 Show fit	42.59	ENST00000274254.9	SKP2 Links Ensembl NCBI GeneCards UniProt Show fit	S-phase kinase associated protein 2
chr10_+_110567666 Show fit	42.44	ENST00000361804.5	SMC3 Links Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 3
chrX_+_123961696 Show fit	41.80	ENST00000371145.8 ENST00000371157.7 ENST00000371144.7	STAG2 Links Ensembl NCBI GeneCards UniProt Show fit	stromal antigen 2
chr1_-_25905989 Show fit	41.30	ENST00000399728.5	STMN1 Links Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr7_-_148884266 Show fit	39.96	ENST00000483967.5 ENST00000320356.7	EZH2 Links Ensembl NCBI GeneCards UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr3_+_44761765 Show fit	39.56	ENST00000326047.9	KIF15 Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 15
chr13_+_113584683 Show fit	39.46	ENST00000375370.10	TFDP1 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-1
chr1_-_25906931 Show fit	39.46	ENST00000357865.6	STMN1 Links Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr10_-_56361235 Show fit	38.68	ENST00000373944.8 ENST00000361148.6 ENST00000395405.5	ZWINT Links Ensembl NCBI GeneCards UniProt Show fit	ZW10 interacting kinetochore protein
chr14_+_51240205 Show fit	38.37	ENST00000457354.7	TMX1 Links Ensembl NCBI GeneCards UniProt Show fit	thioredoxin related transmembrane protein 1
chr20_-_33686371 Show fit	36.54	ENST00000343380.6	E2F1 Links Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 1
chr7_-_148884159 Show fit	36.02	ENST00000478654.5 ENST00000460911.5 ENST00000350995.6	EZH2 Links Ensembl NCBI GeneCards UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr9_-_35079923 Show fit	33.24	ENST00000378643.8 ENST00000448890.1	FANCG Links Ensembl NCBI GeneCards UniProt Show fit	FA complementation group G
chr19_+_36214602 Show fit	33.23	ENST00000456324.5	ZNF146 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 146
chr9_+_97983332 Show fit	33.15	ENST00000339399.5	ANP32B Links Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member B
chr10_+_13161543 Show fit	33.13	ENST00000378714.8 ENST00000479669.5 ENST00000484800.6	MCM10 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance 10 replication initiation factor
chr2_+_47783172 Show fit	32.87	ENST00000540021.6	MSH6 Links Ensembl NCBI GeneCards UniProt Show fit	mutS homolog 6
chr16_+_88803776 Show fit	32.75	ENST00000301019.9	CDT1 Links Ensembl NCBI GeneCards UniProt Show fit	chromatin licensing and DNA replication factor 1
chrX_-_53422170 Show fit	30.93	ENST00000675504.1	SMC1A Links Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 1A
chr3_-_133661896 Show fit	30.34	ENST00000260810.10	TOPBP1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA topoisomerase II binding protein 1
chr6_+_135181268 Show fit	28.35	ENST00000341911.10 ENST00000442647.7 ENST00000618728.4 ENST00000316528.12 ENST00000616088.4	MYB Links Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene, transcription factor
chr2_+_231708511 Show fit	27.97	ENST00000341369.11 ENST00000409115.8 ENST00000409683.5	PTMA Links Ensembl NCBI GeneCards UniProt Show fit	prothymosin alpha
chr16_-_85688912 Show fit	27.79	ENST00000253462.8	GINS2 Links Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 2
chr22_+_20117734 Show fit	27.40	ENST00000416427.5 ENST00000421656.5 ENST00000423859.5 ENST00000418705.2	RANBP1 Links Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 1
chr19_+_36215096 Show fit	27.30	ENST00000443387.3	ZNF146 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 146
chr6_-_18264175 Show fit	26.97	ENST00000651992.1 ENST00000652576.1	DEK Links Ensembl NCBI GeneCards UniProt Show fit	DEK proto-oncogene
chr6_+_135181323 Show fit	26.84	ENST00000367814.8	MYB Links Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene, transcription factor
chr12_-_31326111 Show fit	26.61	ENST00000539409.5	SINHCAF Links Ensembl NCBI GeneCards UniProt Show fit	SIN3-HDAC complex associated factor
chr12_-_31326142 Show fit	26.31	ENST00000337682.9	SINHCAF Links Ensembl NCBI GeneCards UniProt Show fit	SIN3-HDAC complex associated factor
chrX_+_21940693 Show fit	26.04	ENST00000404933.7 ENST00000379404.5	SMS Links Ensembl NCBI GeneCards UniProt Show fit	spermine synthase
chr2_-_46941760 Show fit	25.92	ENST00000444761.6 ENST00000409147.1	MCFD2 Links Ensembl NCBI GeneCards UniProt Show fit	multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr6_-_27146841 Show fit	25.57	ENST00000356950.2	H2BC12 Links Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 12
chr7_-_94656197 Show fit	25.47	ENST00000643903.1 ENST00000644122.1 ENST00000447873.6 ENST00000644816.1 ENST00000644375.1	SGCE Links Ensembl NCBI GeneCards UniProt Show fit	sarcoglycan epsilon
chr15_+_52019206 Show fit	25.46	ENST00000681888.1 ENST00000261845.7 ENST00000680066.1 ENST00000680777.1 ENST00000680652.1	MAPK6 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 6
chr2_-_17753792 Show fit	25.41	ENST00000448223.7 ENST00000621152.4 ENST00000351948.8	SMC6 Links Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 6
chr5_+_36152077 Show fit	25.02	ENST00000546211.6 ENST00000620197.5 ENST00000678270.1 ENST00000679015.1 ENST00000678580.1 ENST00000274255.11 ENST00000508514.5	SKP2 Links Ensembl NCBI GeneCards UniProt Show fit	S-phase kinase associated protein 2
chr16_-_2980282 Show fit	24.38	ENST00000572619.1 ENST00000574415.5 ENST00000440027.6 ENST00000572059.1	PKMYT1 Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase, membrane associated tyrosine/threonine 1
chr2_+_47403116 Show fit	23.96	ENST00000645506.1 ENST00000406134.5 ENST00000233146.7	MSH2 Links Ensembl NCBI GeneCards UniProt Show fit	mutS homolog 2
chr17_+_31937033 Show fit	23.94	ENST00000580398.1	SUZ12 Links Ensembl NCBI GeneCards UniProt Show fit	SUZ12 polycomb repressive complex 2 subunit
chr16_-_2980406 Show fit	23.80	ENST00000431515.6 ENST00000574385.5 ENST00000576268.1 ENST00000574730.5 ENST00000262300.13 ENST00000575632.5 ENST00000573944.5	PKMYT1 Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase, membrane associated tyrosine/threonine 1
chrX_+_119574748 Show fit	23.69	ENST00000628549.1	UBE2A Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 A
chr7_-_94655993 Show fit	23.65	ENST00000647110.1 ENST00000647048.1 ENST00000643020.1 ENST00000644682.1 ENST00000646119.1 ENST00000646265.1 ENST00000645445.1 ENST00000647334.1 ENST00000645262.1 ENST00000428696.7 ENST00000647096.1 ENST00000642394.1 ENST00000645725.1 ENST00000647351.1 ENST00000646943.1 ENST00000648936.2 ENST00000642707.1 ENST00000645109.1 ENST00000646489.1 ENST00000642933.1 ENST00000643128.1 ENST00000445866.7 ENST00000645101.1 ENST00000644116.1 ENST00000642441.1 ENST00000646879.1 ENST00000647018.1	SGCE Links Ensembl NCBI GeneCards UniProt Show fit	sarcoglycan epsilon
chrX_+_107628428 Show fit	23.42	ENST00000643795.2 ENST00000372418.4 ENST00000646815.1 ENST00000372435.10 ENST00000372419.3 ENST00000676092.1	PRPS1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoribosyl pyrophosphate synthetase 1
chr7_+_94656325 Show fit	23.13	ENST00000482108.1 ENST00000488574.5 ENST00000612748.1 ENST00000613043.1	PEG10 Links Ensembl NCBI GeneCards UniProt Show fit	paternally expressed 10
chr1_-_222712428 Show fit	23.02	ENST00000355727.3 ENST00000340020.11	AIDA Links Ensembl NCBI GeneCards UniProt Show fit	axin interactor, dorsalization associated
chr2_+_47403061 Show fit	22.76	ENST00000543555.6	MSH2 Links Ensembl NCBI GeneCards UniProt Show fit	mutS homolog 2
chr17_-_17281232 Show fit	22.63	ENST00000417352.5 ENST00000268717.10	COPS3 Links Ensembl NCBI GeneCards UniProt Show fit	COP9 signalosome subunit 3
chr8_+_127736046 Show fit	22.44	ENST00000641036.1 ENST00000377970.6	MYC Links Ensembl NCBI GeneCards UniProt Show fit	MYC proto-oncogene, bHLH transcription factor
chr17_+_31936993 Show fit	22.04	ENST00000322652.10	SUZ12 Links Ensembl NCBI GeneCards UniProt Show fit	SUZ12 polycomb repressive complex 2 subunit
chr15_+_40695423 Show fit	21.90	ENST00000526763.6 ENST00000532743.6	RAD51 Links Ensembl NCBI GeneCards UniProt Show fit	RAD51 recombinase
chr7_-_94656160 Show fit	21.77	ENST00000644609.1 ENST00000643272.1 ENST00000646137.1 ENST00000646098.1 ENST00000643193.1 ENST00000437425.7 ENST00000644551.1 ENST00000415788.3	SGCE Links Ensembl NCBI GeneCards UniProt Show fit	sarcoglycan epsilon
chr14_+_93207229 Show fit	21.56	ENST00000554232.5 ENST00000556871.5 ENST00000013070.11 ENST00000555113.5	UBR7 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin protein ligase E3 component n-recognin 7
chr8_+_127736220 Show fit	21.47	ENST00000524013.2 ENST00000621592.8	MYC Links Ensembl NCBI GeneCards UniProt Show fit	MYC proto-oncogene, bHLH transcription factor
chr20_-_5119945 Show fit	21.46	ENST00000379143.10	PCNA Links Ensembl NCBI GeneCards UniProt Show fit	proliferating cell nuclear antigen
chr7_+_139359846 Show fit	21.27	ENST00000619796.4 ENST00000354926.9	LUC7L2 Links Ensembl NCBI GeneCards UniProt Show fit	LUC7 like 2, pre-mRNA splicing factor
chr14_+_34982963 Show fit	21.07	ENST00000678627.1 ENST00000216774.11 ENST00000555557.5	SRP54 Links Ensembl NCBI GeneCards UniProt Show fit	signal recognition particle 54
chr4_-_169757873 Show fit	20.82	ENST00000393381.3	HPF1 Links Ensembl NCBI GeneCards UniProt Show fit	histone PARylation factor 1
chr11_+_47215032 Show fit	20.78	ENST00000622090.4 ENST00000378600.7 ENST00000378603.7	DDB2 Links Ensembl NCBI GeneCards UniProt Show fit	damage specific DNA binding protein 2
chr9_+_104094557 Show fit	20.52	ENST00000374787.7	SMC2 Links Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 2
chr7_+_120951116 Show fit	20.38	ENST00000431467.1	ING3 Links Ensembl NCBI GeneCards UniProt Show fit	inhibitor of growth family member 3
chr1_+_149390612 Show fit	20.28	ENST00000650865.1 ENST00000652191.1 ENST00000621744.4	NOTCH2NLC Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000286185.1 Links Ensembl NCBI GeneCards UniProt Show fit	notch 2 N-terminal like C novel protein, identical to neuroblastoma breakpoint family, member 19 NBPF19
chr4_+_128809684 Show fit	20.09	ENST00000226319.11 ENST00000511647.5	JADE1 Links Ensembl NCBI GeneCards UniProt Show fit	jade family PHD finger 1
chr11_+_9384621 Show fit	19.98	ENST00000379719.8 ENST00000527431.1 ENST00000630083.1	IPO7 Links Ensembl NCBI GeneCards UniProt Show fit	importin 7
chr22_+_20117497 Show fit	19.91	ENST00000331821.7 ENST00000411892.5	RANBP1 Links Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 1
chr11_+_47214937 Show fit	19.78	ENST00000256996.9	DDB2 Links Ensembl NCBI GeneCards UniProt Show fit	damage specific DNA binding protein 2
chr1_-_205750167 Show fit	19.22	ENST00000367142.5	NUCKS1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear casein kinase and cyclin dependent kinase substrate 1
chr3_+_52685995 Show fit	19.05	ENST00000394799.6 ENST00000418458.6	GNL3 Links Ensembl NCBI GeneCards UniProt Show fit	G protein nucleolar 3
chr14_+_74881887 Show fit	18.85	ENST00000334220.9 ENST00000626051.1 ENST00000554806.5	DLST Links Ensembl NCBI GeneCards UniProt Show fit	dihydrolipoamide S-succinyltransferase
chr11_-_119095456 Show fit	18.82	ENST00000530167.1	H2AX Links Ensembl NCBI GeneCards UniProt Show fit	H2A.X variant histone
chr12_+_132687570 Show fit	18.63	ENST00000317479.8 ENST00000543589.5	PXMP2 Links Ensembl NCBI GeneCards UniProt Show fit	peroxisomal membrane protein 2
chr4_+_70993542 Show fit	18.61	ENST00000504730.5 ENST00000504952.1 ENST00000286648.10	DCK Links Ensembl NCBI GeneCards UniProt Show fit	deoxycytidine kinase
chr12_+_109098118 Show fit	18.34	ENST00000336865.6	UNG Links Ensembl NCBI GeneCards UniProt Show fit	uracil DNA glycosylase
chrX_+_24693879 Show fit	18.32	ENST00000379068.8 ENST00000677890.1 ENST00000379059.7	POLA1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase alpha 1, catalytic subunit
chrX_+_119574530 Show fit	17.71	ENST00000346330.6 ENST00000625938.2	UBE2A Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 A
chr16_-_23596277 Show fit	17.65	ENST00000562133.5 ENST00000570319.5 ENST00000007516.8	NDUFAB1 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit AB1
chr3_-_119677346 Show fit	17.29	ENST00000484810.5 ENST00000497116.1 ENST00000261070.7	COX17 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase copper chaperone COX17
chrX_+_119574554 Show fit	17.14	ENST00000371558.7 ENST00000630695.2 ENST00000631185.2	UBE2A Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 A
chr7_-_44848021 Show fit	17.06	ENST00000349299.7 ENST00000521529.5 ENST00000350771.7 ENST00000222690.10 ENST00000381124.9 ENST00000437072.5 ENST00000446531.1 ENST00000308153.9	H2AZ2 Links Ensembl NCBI GeneCards UniProt Show fit	H2A.Z variant histone 2
chr4_+_128809791 Show fit	16.76	ENST00000452328.6 ENST00000504089.5	JADE1 Links Ensembl NCBI GeneCards UniProt Show fit	jade family PHD finger 1
chrX_-_53422644 Show fit	16.67	ENST00000322213.9 ENST00000375340.10 ENST00000674590.1	SMC1A Links Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 1A
chr8_+_47960883 Show fit	16.48	ENST00000648407.1 ENST00000649838.1 ENST00000649919.1 ENST00000262105.6 ENST00000649973.1	MCM4 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 4
chrX_+_132023294 Show fit	16.44	ENST00000481105.5 ENST00000354719.10 ENST00000394334.7 ENST00000394335.6	STK26 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 26
chr1_+_32651142 Show fit	16.11	ENST00000414241.7	RBBP4 Links Ensembl NCBI GeneCards UniProt Show fit	RB binding protein 4, chromatin remodeling factor
chr8_-_119855838 Show fit	16.00	ENST00000313655.5	DSCC1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA replication and sister chromatid cohesion 1
chr3_+_14178808 Show fit	15.97	ENST00000306024.4	LSM3 Links Ensembl NCBI GeneCards UniProt Show fit	LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr7_+_120950763 Show fit	15.66	ENST00000339121.9 ENST00000315870.10 ENST00000445699.5	ING3 Links Ensembl NCBI GeneCards UniProt Show fit	inhibitor of growth family member 3
chr5_+_43121596 Show fit	15.38	ENST00000505606.6 ENST00000509634.5 ENST00000509341.5	ZNF131 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 131
chr16_-_11915991 Show fit	15.31	ENST00000420576.6	GSPT1 Links Ensembl NCBI GeneCards UniProt Show fit	G1 to S phase transition 1
chr19_+_10655023 Show fit	15.11	ENST00000590009.5	ILF3 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin enhancer binding factor 3
chr12_+_109097568 Show fit	14.86	ENST00000242576.7	UNG Links Ensembl NCBI GeneCards UniProt Show fit	uracil DNA glycosylase
chr1_-_23980345 Show fit	14.82	ENST00000484146.6	SRSF10 Links Ensembl NCBI GeneCards UniProt Show fit	serine and arginine rich splicing factor 10
chr16_-_50368920 Show fit	14.74	ENST00000394688.8	BRD7 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 7
chr11_+_63974578 Show fit	14.57	ENST00000314133.4 ENST00000535431.1	COX8A Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000256100.1 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 8A novel transcript
chr12_+_57230086 Show fit	14.31	ENST00000414700.7 ENST00000557703.5	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr5_+_43120883 Show fit	14.30	ENST00000515326.5 ENST00000682664.1	ZNF131 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 131
chr9_+_83980757 Show fit	14.25	ENST00000325875.7 ENST00000445877.6	RMI1 Links Ensembl NCBI GeneCards UniProt Show fit	RecQ mediated genome instability 1
chr6_-_159789660 Show fit	14.06	ENST00000538128.5 ENST00000537390.5 ENST00000392168.6	TCP1 Links Ensembl NCBI GeneCards UniProt Show fit	t-complex 1
chr8_+_47961028 Show fit	13.42	ENST00000650216.1	MCM4 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 4
chr10_-_121975168 Show fit	13.24	ENST00000369017.5 ENST00000369023.8	NSMCE4A Links Ensembl NCBI GeneCards UniProt Show fit	NSE4 homolog A, SMC5-SMC6 complex component
chr1_+_32651164 Show fit	13.19	ENST00000373493.10 ENST00000373485.5 ENST00000458695.6	RBBP4 Links Ensembl NCBI GeneCards UniProt Show fit	RB binding protein 4, chromatin remodeling factor
chr5_+_139293700 Show fit	13.09	ENST00000504045.5 ENST00000504311.5 ENST00000502499.5	MATR3 Links Ensembl NCBI GeneCards UniProt Show fit	matrin 3
chr16_+_67562453 Show fit	13.06	ENST00000646076.1	CTCF Links Ensembl NCBI GeneCards UniProt Show fit	CCCTC-binding factor
chr11_-_19241598 Show fit	12.86	ENST00000532666.1 ENST00000527884.5 ENST00000620009.4	E2F8 Links Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 8
chr14_+_60249191 Show fit	12.84	ENST00000395076.9	PPM1A Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1A
chrX_-_153470555 Show fit	12.69	ENST00000370211.10 ENST00000330912.7 ENST00000334497.7 ENST00000338525.7 ENST00000370232.4	HAUS7 Links Ensembl NCBI GeneCards UniProt Show fit TREX2 Links Ensembl NCBI GeneCards UniProt Show fit	HAUS augmin like complex subunit 7 three prime repair exonuclease 2
chr11_+_74592567 Show fit	12.55	ENST00000263681.7 ENST00000527458.5 ENST00000532497.5 ENST00000530511.5	POLD3 Links Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase delta 3, accessory subunit
chr17_-_58007217 Show fit	12.53	ENST00000258962.5 ENST00000582730.6 ENST00000584773.5 ENST00000585096.1	SRSF1 Links Ensembl NCBI GeneCards UniProt Show fit	serine and arginine rich splicing factor 1
chr5_+_140639494 Show fit	12.29	ENST00000252100.6	TMCO6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane and coiled-coil domains 6
chr9_+_104094260 Show fit	12.23	ENST00000286398.11 ENST00000440179.5 ENST00000374793.8	SMC2 Links Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 2
chr16_+_67562514 Show fit	11.97	ENST00000264010.10 ENST00000401394.6 ENST00000646771.1	CTCF Links Ensembl NCBI GeneCards UniProt Show fit	CCCTC-binding factor
chr14_-_69398276 Show fit	11.87	ENST00000557016.6 ENST00000555373.1	ERH Links Ensembl NCBI GeneCards UniProt Show fit	ERH mRNA splicing and mitosis factor
chr5_+_43121504 Show fit	11.86	ENST00000509156.5 ENST00000508259.5 ENST00000306938.8	ZNF131 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 131
chr6_+_20401864 Show fit	11.77	ENST00000346618.8 ENST00000613242.4	E2F3 Links Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 3
chr14_-_67674583 Show fit	11.50	ENST00000554659.6	VTI1B Links Ensembl NCBI GeneCards UniProt Show fit	vesicle transport through interaction with t-SNAREs 1B
chr10_-_13348270 Show fit	11.20	ENST00000378614.8 ENST00000327347.10 ENST00000545675.5	SEPHS1 Links Ensembl NCBI GeneCards UniProt Show fit	selenophosphate synthetase 1
chr19_+_49085433 Show fit	11.03	ENST00000221448.9 ENST00000598441.6	SNRNP70 Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein U1 subunit 70
chr3_-_185938006 Show fit	10.86	ENST00000342294.4 ENST00000453386.7 ENST00000382191.4	TRA2B Links Ensembl NCBI GeneCards UniProt Show fit	transformer 2 beta homolog
chr1_+_120723939 Show fit	10.84	ENST00000624419.2 ENST00000652763.1 ENST00000620612.5	NOTCH2NLR Links Ensembl NCBI GeneCards UniProt Show fit NBPF26 Links Ensembl NCBI GeneCards UniProt Show fit	notch 2 N-terminal like R (pseudogene) NBPF member 26
chr5_+_74767234 Show fit	10.79	ENST00000610426.5	NSA2 Links Ensembl NCBI GeneCards UniProt Show fit	NSA2 ribosome biogenesis factor
chr22_+_35257452 Show fit	10.77	ENST00000420166.5 ENST00000216106.6 ENST00000455359.5	HMGXB4 Links Ensembl NCBI GeneCards UniProt Show fit	HMG-box containing 4
chr17_+_3668803 Show fit	10.63	ENST00000248378.6 ENST00000397133.2	EMC6 Links Ensembl NCBI GeneCards UniProt Show fit	ER membrane protein complex subunit 6
chr6_+_31665234 Show fit	10.58	ENST00000677536.1 ENST00000375885.8	CSNK2B Links Ensembl NCBI GeneCards UniProt Show fit	casein kinase 2 beta
chr5_+_139293728 Show fit	10.51	ENST00000510056.5 ENST00000511249.5 ENST00000394805.8 ENST00000503811.5 ENST00000618441.5	MATR3 Links Ensembl NCBI GeneCards UniProt Show fit	matrin 3
chr17_+_40287861 Show fit	10.37	ENST00000209728.9 ENST00000580824.5 ENST00000577249.1 ENST00000649662.1	CDC6 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 6
chr2_-_99489955 Show fit	10.02	ENST00000393445.7 ENST00000258428.8	REV1 Links Ensembl NCBI GeneCards UniProt Show fit	REV1 DNA directed polymerase
chr16_+_28950807 Show fit	9.81	ENST00000564978.5 ENST00000320805.8	NFATC2IP Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor of activated T cells 2 interacting protein
chr2_-_173965356 Show fit	9.81	ENST00000310015.12	SP3 Links Ensembl NCBI GeneCards UniProt Show fit	Sp3 transcription factor
chr17_+_50719565 Show fit	9.79	ENST00000625349.2 ENST00000393227.6 ENST00000240304.5 ENST00000505658.6 ENST00000505619.5 ENST00000510984.5	LUC7L3 Links Ensembl NCBI GeneCards UniProt Show fit	LUC7 like 3 pre-mRNA splicing factor
chr2_-_27409523 Show fit	9.77	ENST00000344034.5	PPM1G Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1G
chr7_+_6009222 Show fit	9.36	ENST00000400479.6 ENST00000223029.8 ENST00000395236.2	AIMP2 Links Ensembl NCBI GeneCards UniProt Show fit	aminoacyl tRNA synthetase complex interacting multifunctional protein 2
chr5_+_140639419 Show fit	9.32	ENST00000513002.5 ENST00000394671.8	TMCO6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane and coiled-coil domains 6
chr20_-_63216102 Show fit	9.20	ENST00000370339.8 ENST00000370334.4	YTHDF1 Links Ensembl NCBI GeneCards UniProt Show fit	YTH N6-methyladenosine RNA binding protein 1
chrX_+_71533095 Show fit	9.17	ENST00000373719.8 ENST00000373701.7	OGT Links Ensembl NCBI GeneCards UniProt Show fit	O-linked N-acetylglucosamine (GlcNAc) transferase
chr6_+_87590067 Show fit	9.09	ENST00000546266.5 ENST00000257789.4 ENST00000392844.8	ORC3 Links Ensembl NCBI GeneCards UniProt Show fit	origin recognition complex subunit 3
chr6_+_30345131 Show fit	9.06	ENST00000433076.6 ENST00000442966.7 ENST00000428040.6 ENST00000436442.2	RPP21 Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease P/MRP subunit p21
chr3_-_142149515 Show fit	8.95	ENST00000475734.5 ENST00000467072.5 ENST00000489671.6	TFDP2 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2
chr12_+_121888751 Show fit	8.90	ENST00000261817.6 ENST00000538613.5 ENST00000542602.1 ENST00000541212.6	PSMD9 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 9
chr1_-_23344314 Show fit	8.78	ENST00000374612.5 ENST00000675048.1 ENST00000478691.5	HNRNPR Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein R
chr18_-_56651122 Show fit	8.74	ENST00000590954.5	TXNL1 Links Ensembl NCBI GeneCards UniProt Show fit	thioredoxin like 1
chr13_+_97976632 Show fit	8.62	ENST00000490680.5 ENST00000403772.8	IPO5 Links Ensembl NCBI GeneCards UniProt Show fit	importin 5
chr19_-_49929454 Show fit	8.12	ENST00000597723.5 ENST00000599788.1 ENST00000352066.8 ENST00000596217.1 ENST00000593652.5 ENST00000599567.5 ENST00000600935.1 ENST00000596011.1 ENST00000596022.5 ENST00000597295.5	NUP62 Links Ensembl NCBI GeneCards UniProt Show fit IL4I1 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 62 interleukin 4 induced 1
chr1_-_23344259 Show fit	8.07	ENST00000476451.2 ENST00000302271.11 ENST00000606561.5 ENST00000374616.7	HNRNPR Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein R
chr22_-_28741783 Show fit	8.03	ENST00000439200.5 ENST00000405598.5 ENST00000398017.3 ENST00000649563.1 ENST00000650281.1 ENST00000425190.7 ENST00000404276.6 ENST00000650233.1 ENST00000348295.7 ENST00000382580.6	CHEK2 Links Ensembl NCBI GeneCards UniProt Show fit	checkpoint kinase 2
chr12_+_57229694 Show fit	7.98	ENST00000557487.5 ENST00000328923.8 ENST00000555634.5 ENST00000556689.5	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr1_+_226063466 Show fit	7.91	ENST00000666609.1 ENST00000661429.1	H3-3A Links Ensembl NCBI GeneCards UniProt Show fit	H3.3 histone A
chr19_+_2236816 Show fit	7.86	ENST00000221494.10	SF3A2 Links Ensembl NCBI GeneCards UniProt Show fit	splicing factor 3a subunit 2
chr16_-_47461039 Show fit	7.71	ENST00000320640.11	ITFG1 Links Ensembl NCBI GeneCards UniProt Show fit	integrin alpha FG-GAP repeat containing 1
chr3_-_48188356 Show fit	7.70	ENST00000351231.7 ENST00000437972.1 ENST00000302506.8	CDC25A Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 25A
chr3_+_41199389 Show fit	7.40	ENST00000396185.8 ENST00000642986.1 ENST00000644678.1 ENST00000396183.7 ENST00000643031.1 ENST00000645982.1 ENST00000453024.6	CTNNB1 Links Ensembl NCBI GeneCards UniProt Show fit	catenin beta 1
chr5_+_74766981 Show fit	7.39	ENST00000296802.9	NSA2 Links Ensembl NCBI GeneCards UniProt Show fit	NSA2 ribosome biogenesis factor
chr13_+_45120493 Show fit	7.27	ENST00000340473.8	GTF2F2 Links Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIF subunit 2
chr11_-_64778469 Show fit	7.24	ENST00000377387.5	SF1 Links Ensembl NCBI GeneCards UniProt Show fit	splicing factor 1
chr11_+_66616606 Show fit	7.22	ENST00000393979.3 ENST00000409372.1 ENST00000310137.5 ENST00000443702.1 ENST00000409738.4 ENST00000412278.2 ENST00000500635.2	RBM14 Links Ensembl NCBI GeneCards UniProt Show fit RBM14-RBM4 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 14 RBM14-RBM4 readthrough
chr11_-_64778747 Show fit	7.14	ENST00000227503.13 ENST00000377394.7 ENST00000334944.9	SF1 Links Ensembl NCBI GeneCards UniProt Show fit	splicing factor 1
chr6_+_36027796 Show fit	7.08	ENST00000229794.9	MAPK14 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 14
chr11_+_9573633 Show fit	7.05	ENST00000450114.7	WEE1 Links Ensembl NCBI GeneCards UniProt Show fit	WEE1 G2 checkpoint kinase
chr12_+_53454718 Show fit	7.00	ENST00000552819.5 ENST00000455667.7	PCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	poly(rC) binding protein 2
chrX_-_107000185 Show fit	6.89	ENST00000355610.9	MORC4 Links Ensembl NCBI GeneCards UniProt Show fit	MORC family CW-type zinc finger 4
chr15_+_32615501 Show fit	6.85	ENST00000361627.8 ENST00000567348.5 ENST00000563864.5 ENST00000543522.5	ARHGAP11A Links Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 11A
chr16_+_47461290 Show fit	6.77	ENST00000566044.5	PHKB Links Ensembl NCBI GeneCards UniProt Show fit	phosphorylase kinase regulatory subunit beta
chr9_-_128128102 Show fit	6.76	ENST00000617202.4	PTGES2 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E synthase 2
chr17_-_59106801 Show fit	6.66	ENST00000393065.6 ENST00000262294.12 ENST00000393066.7	TRIM37 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 37
chr12_+_93572664 Show fit	6.62	ENST00000551556.2	SOCS2 Links Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 2
chr21_-_28992815 Show fit	6.46	ENST00000361371.10	LTN1 Links Ensembl NCBI GeneCards UniProt Show fit	listerin E3 ubiquitin protein ligase 1
chr19_+_50384323 Show fit	6.35	ENST00000599857.7 ENST00000613923.6 ENST00000601098.6 ENST00000440232.7 ENST00000595904.6 ENST00000593887.1	POLD1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase delta 1, catalytic subunit
chr3_-_9986682 Show fit	6.30	ENST00000429759.5	EMC3 Links Ensembl NCBI GeneCards UniProt Show fit	ER membrane protein complex subunit 3
chr6_+_135181361 Show fit	6.25	ENST00000527615.5 ENST00000420123.6 ENST00000525369.5 ENST00000528774.5 ENST00000533624.5 ENST00000534044.5 ENST00000534121.5	MYB Links Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene, transcription factor
chr16_-_11915878 Show fit	6.19	ENST00000439887.6 ENST00000434724.7	GSPT1 Links Ensembl NCBI GeneCards UniProt Show fit	G1 to S phase transition 1

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
45.3	226.6	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
37.1	111.3	GO:0046452	dihydrofolate metabolic process(GO:0046452)
35.2	457.8	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
30.0	239.7	GO:0090166	regulation of Schwann cell differentiation(GO:0014038) Golgi disassembly(GO:0090166)
25.3	76.0	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
20.5	61.4	GO:1904899	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
18.1	217.6	GO:0070495	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
17.0	84.8	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
16.5	65.9	GO:0035822	gene conversion(GO:0035822)
16.0	16.0	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
11.9	143.3	GO:0001833	inner cell mass cell proliferation(GO:0001833)
11.3	67.6	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
11.1	277.5	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
11.0	131.8	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
11.0	43.9	GO:0090096	metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
11.0	87.8	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
10.7	21.5	GO:0006272	leading strand elongation(GO:0006272)
10.0	50.2	GO:0048478	replication fork protection(GO:0048478)
9.1	9.1	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
8.4	303.1	GO:0006270	DNA replication initiation(GO:0006270)
8.2	81.9	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
7.6	98.7	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
7.2	21.5	GO:0002184	cytoplasmic translational termination(GO:0002184)
7.1	42.7	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
6.9	20.8	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
6.3	18.8	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
5.8	17.3	GO:1904732	regulation of electron carrier activity(GO:1904732)
5.6	22.3	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
5.5	32.8	GO:0010032	meiotic chromosome condensation(GO:0010032)
5.3	21.1	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
5.0	25.0	GO:0040030	regulation of molecular function, epigenetic(GO:0040030)
4.7	23.4	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) AMP biosynthetic process(GO:0006167) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
4.1	40.6	GO:0006290	pyrimidine dimer repair(GO:0006290)
4.0	27.8	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
4.0	31.8	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
3.9	35.3	GO:0000710	meiotic mismatch repair(GO:0000710)
3.8	250.6	GO:0006301	postreplication repair(GO:0006301)
3.7	26.0	GO:0008215	spermine metabolic process(GO:0008215)
3.7	29.3	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
3.3	9.8	GO:0042023	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
3.2	25.4	GO:0000722	telomere maintenance via recombination(GO:0000722)
3.1	9.2	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
3.0	8.9	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
2.8	36.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
2.8	11.0	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
2.7	8.0	GO:0072428	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
2.6	31.0	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
2.3	14.0	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
2.2	15.6	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
2.2	6.5	GO:1903490	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
2.2	25.8	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
2.1	18.6	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
2.0	40.1	GO:0070734	histone H3-K27 methylation(GO:0070734)
2.0	14.0	GO:0006499	N-terminal protein myristoylation(GO:0006499)
2.0	17.6	GO:0009249	protein lipoylation(GO:0009249)
1.9	9.4	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
1.8	12.5	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
1.8	50.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
1.5	13.9	GO:0046600	negative regulation of centriole replication(GO:0046600)
1.5	22.6	GO:0000338	protein deneddylation(GO:0000338)
1.5	19.1	GO:1904816	positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
1.4	11.5	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
1.4	11.2	GO:0001887	selenium compound metabolic process(GO:0001887)
1.4	36.0	GO:0043968	histone H2A acetylation(GO:0043968)
1.3	13.5	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
1.3	10.6	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
1.3	7.9	GO:0060356	leucine import(GO:0060356)
1.2	31.1	GO:0006376	mRNA splice site selection(GO:0006376)
1.1	33.2	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.9	54.5	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.9	16.9	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.9	2.6	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.8	10.9	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.8	2.4	GO:0003420	regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.8	64.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.8	14.2	GO:0000732	strand displacement(GO:0000732)
0.8	10.7	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.7	3.0	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.7	14.6	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.7	1.4	GO:0031393	negative regulation of prostaglandin biosynthetic process(GO:0031393)
0.7	9.1	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.6	16.4	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.6	16.9	GO:0061157	mRNA destabilization(GO:0061157)
0.6	53.9	GO:0045454	cell redox homeostasis(GO:0045454)
0.6	18.2	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.6	5.9	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.5	23.0	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
0.5	1.9	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.4	7.0	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.4	14.7	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.4	2.6	GO:0033504	floor plate development(GO:0033504)
0.4	39.6	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.4	5.4	GO:0070933	histone H4 deacetylation(GO:0070933)
0.4	16.0	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.4	9.0	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4	4.3	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.4	7.3	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.4	6.6	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.4	11.9	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.3	27.0	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.3	4.3	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.3	9.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.3	5.9	GO:0033197	response to vitamin E(GO:0033197)
0.3	0.3	GO:0072387	flavin adenine dinucleotide metabolic process(GO:0072387)
0.3	7.7	GO:1902751	positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.2	20.5	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.2	37.7	GO:0006338	chromatin remodeling(GO:0006338)
0.2	4.3	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.2	3.1	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.2	11.3	GO:0051865	protein autoubiquitination(GO:0051865)
0.2	15.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.2	5.9	GO:0015695	organic cation transport(GO:0015695)
0.2	11.8	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
0.1	9.4	GO:0001541	ovarian follicle development(GO:0001541)
0.1	12.7	GO:0051225	spindle assembly(GO:0051225)
0.1	0.5	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	1.6	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	3.9	GO:0005980	glycogen catabolic process(GO:0005980)
0.1	9.8	GO:0016925	protein sumoylation(GO:0016925)
0.1	9.8	GO:0007062	sister chromatid cohesion(GO:0007062)
0.1	3.9	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.1	28.6	GO:0007160	cell-matrix adhesion(GO:0007160)
0.1	0.8	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.8	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	2.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	5.8	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.1	2.9	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	2.8	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.4	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	1.8	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.4	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	4.1	GO:0008584	male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0	6.1	GO:0006364	rRNA processing(GO:0006364)
0.0	0.6	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
69.4	277.5	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
59.9	239.7	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
44.4	577.6	GO:0042555	MCM complex(GO:0042555)
30.2	120.9	GO:0000811	GINS complex(GO:0000811)
16.4	82.0	GO:0032301	MutSalpha complex(GO:0032301)
14.1	42.4	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
13.9	83.3	GO:0031298	replication fork protection complex(GO:0031298)
13.4	40.2	GO:0035189	Rb-E2F complex(GO:0035189)
11.9	47.6	GO:0030893	meiotic cohesin complex(GO:0030893)
11.7	58.5	GO:0033503	HULC complex(GO:0033503)
9.9	39.6	GO:0005873	plus-end kinesin complex(GO:0005873)
9.8	78.3	GO:0000796	condensin complex(GO:0000796)
9.7	38.7	GO:0030915	Smc5-Smc6 complex(GO:0030915)
9.1	9.1	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
9.0	36.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
8.9	70.9	GO:0016012	sarcoglycan complex(GO:0016012)
8.1	89.3	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
8.1	40.3	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
7.7	62.0	GO:0000243	commitment complex(GO:0000243)
7.6	159.8	GO:0005721	pericentric heterochromatin(GO:0005721)
7.3	29.3	GO:0033186	CAF-1 complex(GO:0033186)
7.2	21.5	GO:0018444	translation release factor complex(GO:0018444)
6.6	46.0	GO:0001739	sex chromatin(GO:0001739)
5.9	23.4	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
5.4	76.0	GO:0045120	pronucleus(GO:0045120)
4.3	21.5	GO:0070557	PCNA-p21 complex(GO:0070557)
3.8	18.9	GO:0043625	delta DNA polymerase complex(GO:0043625)
3.7	18.3	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
3.5	10.6	GO:1903349	omegasome membrane(GO:1903349)
2.9	5.9	GO:0035061	interchromatin granule(GO:0035061)
2.7	18.8	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
2.7	16.0	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
2.7	16.0	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
2.4	7.3	GO:0005674	transcription factor TFIIF complex(GO:0005674)
2.3	21.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
2.3	30.3	GO:0001673	male germ cell nucleus(GO:0001673)
2.3	9.2	GO:0031510	SUMO activating enzyme complex(GO:0031510)
2.3	38.9	GO:0071004	U2-type prespliceosome(GO:0071004)
2.2	29.1	GO:0000800	lateral element(GO:0000800)
2.2	22.3	GO:0070552	BRISC complex(GO:0070552)
2.2	10.8	GO:0016589	NURF complex(GO:0016589)
1.6	9.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.5	10.6	GO:0005956	protein kinase CK2 complex(GO:0005956)
1.4	12.7	GO:0070652	HAUS complex(GO:0070652)
1.3	67.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
1.2	15.6	GO:0002199	zona pellucida receptor complex(GO:0002199)
1.1	14.6	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
1.1	11.9	GO:0034709	methylosome(GO:0034709)
1.1	83.8	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
1.0	10.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.9	9.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.9	6.0	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.8	131.1	GO:0016363	nuclear matrix(GO:0016363)
0.8	6.3	GO:0072546	ER membrane protein complex(GO:0072546)
0.7	71.4	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.7	18.6	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.6	3.4	GO:0042575	DNA polymerase complex(GO:0042575)
0.6	8.9	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.6	18.2	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.5	6.5	GO:0090543	Flemming body(GO:0090543)
0.5	22.6	GO:0008180	COP9 signalosome(GO:0008180)
0.5	86.8	GO:0005819	spindle(GO:0005819)
0.4	42.3	GO:0000775	chromosome, centromeric region(GO:0000775)
0.4	12.5	GO:0035145	exon-exon junction complex(GO:0035145)
0.4	7.9	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.4	5.2	GO:0043601	nuclear replisome(GO:0043601)
0.4	37.2	GO:0036064	ciliary basal body(GO:0036064)
0.3	14.7	GO:0090544	BAF-type complex(GO:0090544)
0.3	152.7	GO:0005874	microtubule(GO:0005874)
0.3	28.6	GO:0005643	nuclear pore(GO:0005643)
0.3	20.6	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3	5.8	GO:0044232	organelle membrane contact site(GO:0044232)
0.3	51.9	GO:0005681	spliceosomal complex(GO:0005681)
0.3	1.6	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2	41.5	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.2	4.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.2	77.1	GO:0043292	contractile fiber(GO:0043292)
0.2	1.9	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2	17.3	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.2	16.4	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.2	7.2	GO:0016592	mediator complex(GO:0016592)
0.2	6.7	GO:0016235	aggresome(GO:0016235)
0.1	8.7	GO:0000502	proteasome complex(GO:0000502)
0.1	93.5	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.1	19.7	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.1	0.8	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	6.4	GO:0016605	PML body(GO:0016605)
0.1	32.2	GO:0005635	nuclear envelope(GO:0005635)
0.1	1.4	GO:0034451	centriolar satellite(GO:0034451)
0.1	70.1	GO:0005730	nucleolus(GO:0005730)
0.1	7.9	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	0.4	GO:0000445	transcription export complex(GO:0000346) THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	41.1	GO:0005615	extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
69.4	277.5	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
27.8	111.3	GO:0004146	dihydrofolate reductase activity(GO:0004146)
16.4	82.0	GO:0032143	single thymine insertion binding(GO:0032143)
14.8	88.9	GO:0036033	mediator complex binding(GO:0036033)
14.1	84.8	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
10.9	239.7	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
10.4	177.6	GO:0003688	DNA replication origin binding(GO:0003688)
10.3	62.0	GO:1990446	U1 snRNP binding(GO:1990446)
10.1	120.9	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
8.7	122.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
8.6	343.9	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
8.3	25.0	GO:0043035	chromatin insulator sequence binding(GO:0043035)
8.3	75.0	GO:1990226	histone methyltransferase binding(GO:1990226)
7.2	21.5	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
6.7	20.0	GO:0045131	pre-mRNA branch point binding(GO:0045131)
5.9	17.6	GO:0000035	acyl binding(GO:0000035)
4.8	38.3	GO:0050733	RS domain binding(GO:0050733)
4.3	51.9	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
4.0	40.4	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
3.9	23.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
3.7	22.3	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
3.5	21.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
3.3	33.2	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
3.1	18.8	GO:0016748	succinyltransferase activity(GO:0016748)
3.1	21.5	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
3.1	9.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.8	80.9	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
2.7	18.6	GO:0004137	deoxycytidine kinase activity(GO:0004137)
2.6	28.6	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.2	17.3	GO:0016531	copper chaperone activity(GO:0016531)
2.1	12.7	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
1.8	198.8	GO:0070491	repressing transcription factor binding(GO:0070491)
1.7	8.7	GO:0047134	protein-disulfide reductase activity(GO:0047134)
1.6	377.5	GO:0042393	histone binding(GO:0042393)
1.6	38.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.6	14.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
1.4	14.0	GO:0051525	NFAT protein binding(GO:0051525)
1.4	19.0	GO:0031386	protein tag(GO:0031386)
1.4	6.8	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
1.3	58.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
1.3	15.4	GO:0019869	chloride channel inhibitor activity(GO:0019869)
1.2	31.8	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
1.0	10.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
1.0	25.5	GO:0004707	MAP kinase activity(GO:0004707)
1.0	107.4	GO:0004386	helicase activity(GO:0004386)
0.9	1.9	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.9	3.7	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.9	7.0	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.8	6.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.8	16.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.8	9.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.7	37.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.7	6.0	GO:0034511	U3 snoRNA binding(GO:0034511)
0.7	4.6	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.7	6.5	GO:0051425	PTB domain binding(GO:0051425)
0.6	7.9	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.5	14.6	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5	39.6	GO:0003777	microtubule motor activity(GO:0003777)
0.5	1.4	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.5	15.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.5	2.3	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.5	5.0	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.4	66.9	GO:0031072	heat shock protein binding(GO:0031072)
0.4	154.9	GO:0015631	tubulin binding(GO:0015631)
0.4	16.7	GO:0036002	pre-mRNA binding(GO:0036002)
0.4	5.2	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.4	151.4	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.3	8.6	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.3	60.5	GO:0008201	heparin binding(GO:0008201)
0.3	26.0	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.3	15.6	GO:0033613	activating transcription factor binding(GO:0033613)
0.3	34.6	GO:0047485	protein N-terminus binding(GO:0047485)
0.3	2.8	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.3	3.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.3	51.8	GO:0001047	core promoter binding(GO:0001047)
0.2	7.2	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.2	8.9	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.2	15.1	GO:0003725	double-stranded RNA binding(GO:0003725)
0.2	5.9	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.2	16.9	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.1	18.3	GO:0008565	protein transporter activity(GO:0008565)
0.1	0.8	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	8.1	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.1	2.9	GO:0048038	quinone binding(GO:0048038)
0.1	28.8	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.1	10.3	GO:0016779	nucleotidyltransferase activity(GO:0016779)
0.1	7.1	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	14.1	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1	23.0	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.1	3.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	14.4	GO:0003713	transcription coactivator activity(GO:0003713)
0.1	5.9	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.6	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	23.6	GO:0005198	structural molecule activity(GO:0005198)
0.0	23.8	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.1	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	1.6	GO:0051015	actin filament binding(GO:0051015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.2	254.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
10.9	217.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
5.4	326.8	PID ATR PATHWAY	ATR signaling pathway
5.1	616.7	PID E2F PATHWAY	E2F transcription factor network
3.4	98.1	PID ATM PATHWAY	ATM pathway
1.9	67.6	PID MYC PATHWAY	C-MYC pathway
1.3	14.2	PID FANCONI PATHWAY	Fanconi anemia pathway
1.1	61.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
1.1	100.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.7	41.8	PID PLK1 PATHWAY	PLK1 signaling events
0.6	109.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.5	6.8	PID IFNG PATHWAY	IFN-gamma pathway
0.5	9.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.4	16.0	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	10.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.3	6.6	PID IL2 1PATHWAY	IL2-mediated signaling events
0.3	24.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.2	7.4	PID AURORA B PATHWAY	Aurora B signaling
0.1	9.8	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	5.6	PID LKB1 PATHWAY	LKB1 signaling events
0.1	2.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	5.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	4.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	3.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
46.5	697.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
26.5	795.0	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
13.4	200.7	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
4.4	78.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
2.4	55.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
2.4	18.9	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
2.1	107.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
1.9	75.0	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
1.7	29.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
1.7	77.0	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
1.6	29.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
1.4	124.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
1.4	39.6	REACTOME KINESINS	Genes involved in Kinesins
1.3	8.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
1.3	72.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
1.3	26.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
1.1	25.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.1	8.6	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
1.0	9.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.9	16.0	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.8	89.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.8	18.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.7	18.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.7	14.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.6	14.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.5	2.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.5	66.8	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.5	15.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.4	38.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.4	35.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.4	9.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.4	10.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	28.1	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.3	62.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2	7.9	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.2	10.6	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	3.9	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	21.1	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	2.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	2.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	5.9	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.0	0.9	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling