GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
E2F4 | hg38_v1_chr16_+_67192116_67192225 | 0.18 | 8.3e-03 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.8 | 95.1 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
4.4 | 57.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
12.8 | 38.4 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
4.2 | 37.7 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
8.8 | 26.5 | GO:0010520 | meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520) |
0.3 | 24.1 | GO:0032392 | DNA geometric change(GO:0032392) |
7.7 | 23.2 | GO:1990922 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
3.7 | 22.3 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.3 | 22.1 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
1.7 | 20.4 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
21.2 | 84.9 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
4.8 | 62.8 | GO:0042555 | MCM complex(GO:0042555) |
0.3 | 45.9 | GO:0016363 | nuclear matrix(GO:0016363) |
7.0 | 35.0 | GO:0032301 | MutSalpha complex(GO:0032301) |
3.8 | 34.6 | GO:0036449 | microtubule minus-end(GO:0036449) |
2.0 | 22.3 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
2.9 | 20.3 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
4.6 | 18.6 | GO:0033186 | CAF-1 complex(GO:0033186) |
0.2 | 17.8 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
2.1 | 16.5 | GO:0000796 | condensin complex(GO:0000796) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
21.2 | 84.9 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
1.2 | 53.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
7.0 | 35.0 | GO:0032143 | single thymine insertion binding(GO:0032143) |
0.8 | 33.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.2 | 32.3 | GO:0042393 | histone binding(GO:0042393) |
8.0 | 32.2 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
0.4 | 29.9 | GO:0003684 | damaged DNA binding(GO:0003684) |
2.1 | 23.2 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
1.0 | 22.6 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
5.1 | 20.4 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 185.3 | PID E2F PATHWAY | E2F transcription factor network |
0.9 | 49.9 | PID ATR PATHWAY | ATR signaling pathway |
0.4 | 26.7 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
0.2 | 26.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.2 | 23.5 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.5 | 19.5 | PID MYC PATHWAY | C-MYC pathway |
0.2 | 17.3 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
0.1 | 12.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.5 | 12.6 | PID ATM PATHWAY | ATM pathway |
0.2 | 9.4 | PID AURORA B PATHWAY | Aurora B signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 106.9 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
5.1 | 77.2 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
0.4 | 38.1 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
2.1 | 32.2 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
1.0 | 29.7 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
0.4 | 29.6 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
0.2 | 28.1 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
1.2 | 27.9 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
1.5 | 22.1 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
1.6 | 20.9 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |