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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for E2F4

Z-value: 0.99

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Transcription factors associated with E2F4

Gene Symbol Gene ID Gene Info
ENSG00000205250.9 E2F4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F4hg38_v1_chr16_+_67192116_671922250.188.3e-03Click!

Activity profile of E2F4 motif

GNF_1_721_B_lymphoblastsGNF_1_AmygdalaGNF_1_BM-CD34+GNF_1_bronchialepithelialcellsGNF_1_CerebellumPedunclesGNF_1_DRGGNF_1_fetalThyroidGNF_1_kidneyGNF_1_LiverGNF_1_lymphomaburkittsRajiGNF_1_OvaryGNF_1_PB-BDCA4+Dentritic_CellsGNF_1_PB-CD19+BcellsGNF_1_PonsGNF_1_SkeletalMuscleGNF_1_subthalamicnucleusGNF_1_TestisGermCellGNF_1_ThalamusGNF_1_TonsilGNF_1_UterusCorpusGNF_2_ADIPOCYTEGNF_2_AppendixGNF_2_BM-CD71+EarlyErythroidGNF_2_CardiacMyocytesGNF_2_ciliaryganglionGNF_2_fetalbrainGNF_2_globuspallidusGNF_2_leukemiachronicmyelogenous(k562)GNF_2_LungGNF_2_MedullaOblongataGNF_2_PancreasGNF_2_PB-CD4+TcellsGNF_2_PB-CD56+NKCellsGNF_2_PrefrontalCortexGNF_2_skinGNF_2_SuperiorCervicalGanglionGNF_2_TestisInterstitialGNF_2_thymusGNF_2_tracheaGNF_2_WHOLEBLOODNCI60_1_A549_ATCCNCI60_1_CCRF-CEMNCI60_1_HCC-2998NCI60_1_HOP-92NCI60_1_IGROV1_rep1NCI60_1_LOXIMVINCI60_1_MDA-MB-435NCI60_1_NCI-ADR-RESNCI60_1_NCI-H522NCI60_1_OVCAR-3NCI60_1_SF-539NCI60_1_SK-MEL-5NCI60_1_SNB-75NCI60_1_T47DNCI60_1_UACC-62−0.15−0.1−0.0500.050.10.15

Sorted Z-values of E2F4 motif

−3−2−10123GNF_2_SmoothMuscleGNF_1_ADIPOCYTEGNF_2_ADIPOCYTEGNF_2_WholeBrainGNF_1_OlfactoryBulbGNF_2_LungGNF_1_LiverGNF_1_fetalbrainGNF_2_ciliaryganglionGNF_2_lymphnodeGNF_2_subthalamicnucleusGNF_1_adrenalglandGNF_1_UterusGNF_1_ciliaryganglionGNF_2_OvaryGNF_1_ProstateGNF_2_skinGNF_1_OccipitalLobeGNF_1_ThyroidGNF_2_DRGGNF_2_cerebellumGNF_2_atrioventricularnodeGNF_2_testisGNF_1_CerebellumPedunclesGNF_2_AppendixNCI60_1_RXF-393GNF_1_fetalliverNCI60_1_786-0GNF_2_TestisLeydigCellGNF_1_lymphomaburkittsRajiNCI60_1_IGROV1_rep1NCI60_1_SNB-75GNF_2_thymusGNF_1_TestisGermCellGNF_1_BM-CD71+EarlyErythroidGNF_1_UterusCorpusGNF_2_BM-CD105+EndothelialGNF_1_leukemiapromyelocytic(hl60)NCI60_1_OVCAR-8GNF_2_721_B_lymphoblastsNCI60_1_SK-MEL-28NCI60_1_OVCAR-3NCI60_1_HL-60NCI60_1_CCRF-CEM

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: