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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for E2F7_E2F1
Z-value: 4.51
Motif logo
Transcription factors associated with E2F7_E2F1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
E2F7
|
ENSG00000165891.16 | E2F7 |
|
E2F1
|
ENSG00000101412.13 | E2F1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| E2F1 | hg38_v1_chr20_-_33686371_33686407 | 0.74 | 1.0e-39 | Click! |
Activity profile of E2F7_E2F1 motif
Sorted Z-values of E2F7_E2F1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of E2F7_E2F1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 85.5 | 256.5 | GO:0006311 | meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520) |
| 76.8 | 307.0 | GO:0019860 | uracil metabolic process(GO:0019860) |
| 66.1 | 198.4 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 49.5 | 148.5 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 45.2 | 587.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 39.7 | 198.5 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 39.0 | 117.0 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 38.1 | 114.3 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 36.1 | 180.5 | GO:1904636 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 35.1 | 140.5 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 33.4 | 100.1 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 32.8 | 131.2 | GO:0090095 | metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 31.4 | 94.1 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 30.6 | 91.9 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 28.5 | 227.9 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 28.5 | 626.2 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 28.1 | 168.8 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 25.3 | 126.3 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 25.1 | 226.2 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 24.9 | 74.6 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 24.4 | 73.3 | GO:0008614 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) |
| 24.1 | 168.4 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 23.8 | 47.6 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
| 23.0 | 69.1 | GO:1902269 | positive regulation of polyamine transmembrane transport(GO:1902269) |
| 23.0 | 298.9 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 22.7 | 136.4 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 22.4 | 89.4 | GO:0072423 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 21.9 | 87.7 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 21.9 | 65.6 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
| 21.5 | 64.6 | GO:0034473 | U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) |
| 20.2 | 40.4 | GO:1902990 | mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
| 19.9 | 59.8 | GO:1901254 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 19.6 | 137.4 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 19.5 | 58.5 | GO:0051793 | medium-chain fatty acid catabolic process(GO:0051793) |
| 19.3 | 57.8 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 19.1 | 57.4 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 18.5 | 221.5 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 17.4 | 69.7 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 17.2 | 34.5 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 16.2 | 194.9 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 16.0 | 48.1 | GO:1904430 | negative regulation of t-circle formation(GO:1904430) |
| 15.2 | 45.7 | GO:0032954 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 15.1 | 45.2 | GO:0070512 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
| 14.8 | 59.2 | GO:1904045 | cellular response to aldosterone(GO:1904045) |
| 14.2 | 42.6 | GO:1904897 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 13.8 | 110.7 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 13.7 | 150.6 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 13.5 | 94.4 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 13.0 | 77.7 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 12.9 | 38.7 | GO:2000174 | regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 12.2 | 73.2 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 11.9 | 59.7 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 11.9 | 35.7 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 11.8 | 117.6 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 11.6 | 46.6 | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) |
| 11.6 | 473.6 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 11.2 | 33.5 | GO:0009996 | negative regulation of cell fate specification(GO:0009996) |
| 11.1 | 33.2 | GO:0071072 | negative regulation of phospholipid biosynthetic process(GO:0071072) |
| 10.9 | 283.1 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 10.8 | 32.5 | GO:0014810 | positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810) |
| 10.7 | 193.1 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 10.7 | 85.5 | GO:0085020 | protein K6-linked ubiquitination(GO:0085020) |
| 10.5 | 31.6 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
| 10.4 | 62.3 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 10.3 | 61.9 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 10.2 | 61.3 | GO:0015853 | adenine transport(GO:0015853) |
| 10.2 | 51.1 | GO:0071033 | nuclear retention of pre-mRNA at the site of transcription(GO:0071033) |
| 10.0 | 39.9 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 10.0 | 89.6 | GO:0009157 | deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) |
| 9.9 | 49.4 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 9.8 | 29.4 | GO:0071314 | cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373) |
| 9.7 | 29.0 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 9.6 | 57.8 | GO:1903679 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 9.6 | 28.8 | GO:0003064 | regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 9.3 | 28.0 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 9.3 | 37.4 | GO:0048627 | myoblast development(GO:0048627) |
| 9.2 | 64.5 | GO:0032218 | riboflavin transport(GO:0032218) |
| 9.1 | 27.3 | GO:1901874 | negative regulation of post-translational protein modification(GO:1901874) |
| 8.9 | 44.3 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 8.8 | 52.9 | GO:2000371 | regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 8.8 | 26.4 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
| 8.7 | 26.1 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 8.7 | 112.6 | GO:0046689 | response to mercury ion(GO:0046689) |
| 8.6 | 77.8 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 8.4 | 50.7 | GO:0003164 | His-Purkinje system development(GO:0003164) |
| 8.3 | 25.0 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
| 8.3 | 24.9 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 8.1 | 24.4 | GO:2000374 | regulation of oxygen metabolic process(GO:2000374) |
| 7.8 | 47.0 | GO:0019060 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 7.8 | 15.6 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 7.8 | 23.3 | GO:0051821 | negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821) |
| 7.6 | 114.1 | GO:0070986 | left/right axis specification(GO:0070986) |
| 7.6 | 105.9 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 7.5 | 45.1 | GO:0009113 | purine nucleobase biosynthetic process(GO:0009113) |
| 7.3 | 66.0 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 7.2 | 21.7 | GO:0003420 | regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) |
| 7.1 | 21.3 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
| 7.1 | 49.4 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 6.9 | 41.4 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 6.9 | 34.5 | GO:0010266 | response to vitamin B1(GO:0010266) |
| 6.9 | 13.7 | GO:0039019 | pronephric nephron development(GO:0039019) |
| 6.4 | 63.7 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 6.3 | 182.7 | GO:0006465 | signal peptide processing(GO:0006465) |
| 6.1 | 258.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 6.0 | 36.3 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 5.8 | 23.2 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) |
| 5.8 | 17.4 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 5.8 | 63.4 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 5.7 | 17.1 | GO:1901970 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
| 5.7 | 22.7 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 5.6 | 16.9 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 5.6 | 27.9 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 5.4 | 54.4 | GO:0006290 | pyrimidine dimer repair(GO:0006290) |
| 5.4 | 37.7 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 5.4 | 16.1 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 5.3 | 186.8 | GO:0019985 | translesion synthesis(GO:0019985) |
| 5.3 | 31.7 | GO:0006301 | postreplication repair(GO:0006301) |
| 5.3 | 47.5 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 5.2 | 10.4 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 5.1 | 5.1 | GO:0072387 | flavin adenine dinucleotide metabolic process(GO:0072387) |
| 5.0 | 40.1 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 5.0 | 25.1 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
| 5.0 | 134.1 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 4.9 | 69.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 4.9 | 29.7 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 4.9 | 39.4 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 4.9 | 98.3 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 4.9 | 83.2 | GO:0042761 | fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 4.9 | 53.6 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 4.9 | 82.6 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 4.8 | 19.3 | GO:1903121 | rhythmic synaptic transmission(GO:0060024) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 4.8 | 19.2 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 4.8 | 14.3 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 4.7 | 42.6 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 4.7 | 23.5 | GO:0044789 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 4.7 | 14.0 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 4.6 | 9.2 | GO:0048319 | axial mesoderm morphogenesis(GO:0048319) |
| 4.6 | 41.0 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 4.5 | 40.8 | GO:0032057 | negative regulation of translational initiation in response to stress(GO:0032057) |
| 4.5 | 71.9 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 4.4 | 22.2 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 4.4 | 13.3 | GO:1990918 | meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918) |
| 4.4 | 43.8 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
| 4.3 | 25.6 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 4.2 | 21.0 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 4.2 | 12.6 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 4.1 | 33.2 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 4.1 | 16.5 | GO:1903803 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 4.0 | 24.1 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 4.0 | 91.0 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 3.9 | 78.6 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 3.9 | 74.6 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 3.8 | 68.9 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
| 3.8 | 172.2 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 3.8 | 15.3 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 3.8 | 15.1 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 3.8 | 26.4 | GO:0007144 | female meiosis I(GO:0007144) |
| 3.8 | 26.4 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 3.8 | 45.1 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 3.7 | 15.0 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 3.7 | 15.0 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 3.7 | 234.1 | GO:0006378 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 3.6 | 7.3 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 3.6 | 32.7 | GO:0017062 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 3.6 | 7.2 | GO:0097240 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 3.6 | 17.9 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 3.6 | 7.2 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 3.6 | 53.5 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 3.6 | 42.7 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 3.5 | 46.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 3.5 | 24.7 | GO:0008215 | spermine metabolic process(GO:0008215) |
| 3.5 | 24.3 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 3.4 | 300.4 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 3.4 | 23.7 | GO:1902962 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 3.3 | 36.8 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 3.3 | 249.2 | GO:0051439 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) |
| 3.3 | 9.8 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 3.3 | 13.0 | GO:0046946 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 3.2 | 12.9 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 3.2 | 32.1 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 3.1 | 15.7 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 3.1 | 9.2 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 3.0 | 9.1 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 3.0 | 12.2 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 3.0 | 33.4 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 3.0 | 5.9 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) |
| 2.9 | 14.7 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 2.9 | 29.4 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 2.9 | 49.2 | GO:0000732 | strand displacement(GO:0000732) |
| 2.8 | 14.2 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 2.8 | 8.5 | GO:0035425 | autocrine signaling(GO:0035425) |
| 2.8 | 19.7 | GO:2000561 | CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) |
| 2.8 | 5.6 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 2.8 | 13.9 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 2.8 | 11.1 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 2.8 | 55.3 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 2.7 | 60.2 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 2.7 | 8.2 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 2.7 | 21.4 | GO:0000012 | single strand break repair(GO:0000012) |
| 2.7 | 10.7 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 2.6 | 5.3 | GO:0044416 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) |
| 2.6 | 49.6 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 2.6 | 54.6 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
| 2.6 | 41.6 | GO:0007097 | nuclear migration(GO:0007097) |
| 2.6 | 13.0 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
| 2.6 | 15.4 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 2.6 | 12.8 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 2.5 | 19.9 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 2.5 | 9.9 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 2.4 | 9.7 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 2.4 | 12.1 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 2.4 | 26.4 | GO:0033015 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 2.4 | 9.5 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) |
| 2.3 | 30.4 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 2.3 | 16.3 | GO:0030421 | defecation(GO:0030421) |
| 2.3 | 120.4 | GO:0032392 | DNA geometric change(GO:0032392) |
| 2.3 | 6.9 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 2.3 | 13.7 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 2.3 | 29.6 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 2.3 | 11.4 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 2.3 | 36.3 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 2.3 | 31.8 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 2.3 | 38.4 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 2.3 | 11.3 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
| 2.2 | 8.9 | GO:0032025 | response to cobalt ion(GO:0032025) |
| 2.2 | 19.8 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 2.2 | 239.9 | GO:0051225 | spindle assembly(GO:0051225) |
| 2.2 | 13.0 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 2.2 | 13.0 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 2.1 | 23.6 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 2.1 | 32.1 | GO:0045116 | protein neddylation(GO:0045116) |
| 2.1 | 31.0 | GO:0033260 | nuclear DNA replication(GO:0033260) |
| 2.1 | 61.8 | GO:0072663 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 2.1 | 10.3 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 2.0 | 24.5 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 2.0 | 16.2 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 2.0 | 6.1 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 2.0 | 20.2 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 2.0 | 212.1 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 2.0 | 6.0 | GO:0061074 | regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866) |
| 2.0 | 8.0 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 2.0 | 20.0 | GO:1902177 | positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177) |
| 2.0 | 16.0 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 2.0 | 6.0 | GO:1900110 | negative regulation of histone H3-K9 dimethylation(GO:1900110) |
| 2.0 | 144.2 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 2.0 | 3.9 | GO:0060743 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 2.0 | 5.9 | GO:0072709 | cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672) |
| 1.9 | 9.7 | GO:0009048 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 1.9 | 1.9 | GO:0002901 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 1.9 | 9.5 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 1.9 | 9.5 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 1.9 | 9.4 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 1.8 | 9.2 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 1.8 | 10.9 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 1.8 | 10.8 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 1.8 | 16.2 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 1.8 | 21.4 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 1.8 | 8.9 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 1.8 | 21.3 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 1.8 | 8.9 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 1.8 | 7.1 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 1.8 | 22.9 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 1.8 | 12.3 | GO:1901315 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 1.8 | 3.5 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 1.8 | 42.0 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 1.7 | 7.0 | GO:0030047 | actin modification(GO:0030047) |
| 1.7 | 60.9 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 1.7 | 103.7 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 1.7 | 5.2 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
| 1.7 | 5.1 | GO:0043311 | renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) positive regulation of eosinophil degranulation(GO:0043311) regulation of renin secretion into blood stream(GO:1900133) positive regulation of eosinophil activation(GO:1902568) |
| 1.7 | 26.8 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 1.6 | 18.1 | GO:0046599 | regulation of centriole replication(GO:0046599) |
| 1.6 | 19.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 1.6 | 4.8 | GO:0040031 | snRNA modification(GO:0040031) |
| 1.6 | 12.7 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 1.6 | 3.1 | GO:2000850 | negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 1.5 | 13.9 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 1.5 | 4.5 | GO:0010693 | negative regulation of alkaline phosphatase activity(GO:0010693) |
| 1.5 | 4.5 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
| 1.5 | 10.5 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 1.5 | 13.5 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
| 1.5 | 5.9 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 1.5 | 54.3 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 1.5 | 17.6 | GO:0010917 | negative regulation of mitochondrial membrane potential(GO:0010917) |
| 1.4 | 11.3 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 1.4 | 7.0 | GO:0003415 | chondrocyte hypertrophy(GO:0003415) |
| 1.4 | 45.9 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 1.4 | 18.0 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 1.4 | 5.5 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 1.4 | 73.3 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 1.4 | 27.3 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 1.3 | 20.2 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 1.3 | 8.0 | GO:0018916 | nitrobenzene metabolic process(GO:0018916) |
| 1.3 | 15.7 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 1.3 | 20.4 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
| 1.3 | 13.9 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 1.3 | 6.3 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 1.2 | 28.7 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 1.2 | 5.0 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 1.2 | 16.0 | GO:0043174 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) nucleoside salvage(GO:0043174) |
| 1.2 | 39.3 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
| 1.2 | 7.4 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 1.2 | 10.9 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 1.2 | 4.9 | GO:0080009 | mRNA methylation(GO:0080009) |
| 1.2 | 4.8 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986) |
| 1.2 | 60.5 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 1.2 | 14.2 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 1.1 | 133.3 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 1.1 | 46.6 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 1.1 | 4.4 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 1.1 | 9.9 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 1.1 | 14.3 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 1.1 | 13.2 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 1.1 | 1.1 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 1.1 | 13.9 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 1.1 | 32.1 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 1.1 | 43.7 | GO:0006513 | protein monoubiquitination(GO:0006513) |
| 1.1 | 4.3 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 1.1 | 9.5 | GO:0035608 | protein deglutamylation(GO:0035608) |
| 1.0 | 18.8 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 1.0 | 4.1 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 1.0 | 1.0 | GO:0072054 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
| 1.0 | 2.0 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 1.0 | 42.0 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 1.0 | 13.6 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 1.0 | 5.7 | GO:0060356 | leucine import(GO:0060356) |
| 1.0 | 1.0 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
| 0.9 | 40.6 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.9 | 22.6 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.9 | 13.7 | GO:0043928 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.9 | 4.5 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.9 | 15.4 | GO:0040001 | establishment of mitotic spindle localization(GO:0040001) |
| 0.9 | 13.6 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.9 | 10.8 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.8 | 61.1 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.8 | 15.1 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.8 | 1.7 | GO:0045144 | meiotic sister chromatid segregation(GO:0045144) |
| 0.8 | 17.5 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.8 | 20.6 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.8 | 14.8 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.8 | 3.3 | GO:0043335 | protein unfolding(GO:0043335) |
| 0.8 | 30.3 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.8 | 2.4 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.8 | 16.7 | GO:0090224 | regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224) |
| 0.8 | 5.5 | GO:0019720 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 0.8 | 6.3 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
| 0.8 | 22.5 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.8 | 1.5 | GO:0090107 | regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 0.7 | 30.6 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.7 | 29.5 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
| 0.7 | 2.9 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.7 | 14.4 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
| 0.7 | 6.4 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.7 | 8.2 | GO:0042255 | ribosome assembly(GO:0042255) |
| 0.7 | 6.1 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.7 | 1.4 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.7 | 3.4 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.7 | 2.0 | GO:0045047 | protein targeting to ER(GO:0045047) |
| 0.7 | 14.9 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.7 | 8.8 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.7 | 1.3 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.7 | 14.7 | GO:0060706 | cell differentiation involved in embryonic placenta development(GO:0060706) |
| 0.7 | 2.0 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.7 | 6.6 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.7 | 4.6 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.6 | 1.9 | GO:0021943 | formation of radial glial scaffolds(GO:0021943) |
| 0.6 | 26.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.6 | 42.5 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.6 | 1.2 | GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) |
| 0.6 | 7.7 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.6 | 14.1 | GO:0051923 | sulfation(GO:0051923) |
| 0.6 | 2.3 | GO:1904715 | regulation of protein folding(GO:1903332) negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 0.6 | 1.1 | GO:0038162 | erythropoietin-mediated signaling pathway(GO:0038162) |
| 0.6 | 15.0 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.5 | 2.2 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.5 | 30.1 | GO:0031640 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.5 | 3.7 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.5 | 4.2 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.5 | 3.7 | GO:0042789 | mRNA transcription from RNA polymerase II promoter(GO:0042789) |
| 0.5 | 11.3 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.5 | 5.1 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.5 | 3.0 | GO:0044415 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136) |
| 0.5 | 41.5 | GO:0090114 | COPII-coated vesicle budding(GO:0090114) |
| 0.5 | 8.9 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.5 | 4.4 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.5 | 13.6 | GO:0030838 | positive regulation of actin filament polymerization(GO:0030838) |
| 0.5 | 10.9 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
| 0.5 | 4.3 | GO:0019054 | modulation by virus of host process(GO:0019054) |
| 0.5 | 14.9 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.5 | 36.1 | GO:0006364 | rRNA processing(GO:0006364) |
| 0.5 | 5.1 | GO:2000269 | regulation of fibroblast apoptotic process(GO:2000269) positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.5 | 2.7 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.5 | 3.2 | GO:0015705 | iodide transport(GO:0015705) |
| 0.5 | 29.1 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.5 | 35.4 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.4 | 10.8 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.4 | 10.3 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.4 | 19.3 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.4 | 6.2 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.4 | 8.8 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.4 | 24.4 | GO:0032481 | positive regulation of type I interferon production(GO:0032481) |
| 0.4 | 1.7 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.4 | 0.9 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.4 | 3.0 | GO:1903416 | response to glycoside(GO:1903416) |
| 0.4 | 10.7 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
| 0.4 | 10.5 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.4 | 3.3 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.4 | 10.9 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.4 | 4.5 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.4 | 6.9 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.4 | 0.8 | GO:0071888 | macrophage apoptotic process(GO:0071888) |
| 0.4 | 17.7 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.4 | 0.8 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.4 | 4.3 | GO:1904886 | beta-catenin destruction complex disassembly(GO:1904886) |
| 0.4 | 0.4 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 0.4 | 20.0 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.4 | 5.4 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.4 | 2.3 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.4 | 27.6 | GO:0048278 | vesicle docking(GO:0048278) |
| 0.4 | 3.3 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.4 | 2.5 | GO:0032506 | cytokinetic process(GO:0032506) |
| 0.4 | 2.5 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.4 | 3.9 | GO:0042407 | cristae formation(GO:0042407) |
| 0.4 | 9.5 | GO:0007051 | spindle organization(GO:0007051) |
| 0.3 | 2.1 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.3 | 2.4 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.3 | 1.0 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.3 | 0.7 | GO:1900127 | positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 0.3 | 6.5 | GO:0006303 | double-strand break repair via nonhomologous end joining(GO:0006303) |
| 0.3 | 9.7 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.3 | 8.4 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.3 | 14.5 | GO:0051881 | regulation of mitochondrial membrane potential(GO:0051881) |
| 0.3 | 7.3 | GO:0042254 | ribosome biogenesis(GO:0042254) |
| 0.3 | 3.4 | GO:0030210 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.3 | 13.7 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.3 | 1.9 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 0.3 | 2.5 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.3 | 10.2 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.3 | 3.4 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.3 | 13.3 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.3 | 7.2 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
| 0.3 | 5.5 | GO:0002828 | regulation of type 2 immune response(GO:0002828) |
| 0.3 | 1.8 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.2 | 17.7 | GO:0030148 | sphingolipid biosynthetic process(GO:0030148) |
| 0.2 | 14.3 | GO:0006413 | translational initiation(GO:0006413) |
| 0.2 | 13.4 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.2 | 1.3 | GO:0098838 | methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838) |
| 0.2 | 1.6 | GO:0030238 | male sex determination(GO:0030238) |
| 0.2 | 1.0 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.2 | 1.6 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.2 | 2.3 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.2 | 1.2 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.2 | 5.2 | GO:0019835 | cytolysis(GO:0019835) |
| 0.2 | 16.4 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
| 0.2 | 2.9 | GO:0030220 | platelet formation(GO:0030220) |
| 0.2 | 4.2 | GO:0031529 | ruffle organization(GO:0031529) |
| 0.2 | 4.2 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.2 | 1.0 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 0.2 | 12.2 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 7.1 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.1 | 4.1 | GO:0006672 | ceramide metabolic process(GO:0006672) |
| 0.1 | 15.2 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.1 | 1.1 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.1 | 3.8 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.1 | 0.2 | GO:0003418 | growth plate cartilage chondrocyte differentiation(GO:0003418) |
| 0.1 | 0.6 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.1 | 1.0 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.1 | 0.3 | GO:0071386 | cellular response to corticosterone stimulus(GO:0071386) |
| 0.1 | 2.3 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 0.5 | GO:0036486 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 0.1 | 1.7 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.1 | 0.9 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.0 | 3.0 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 2.0 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.0 | 0.3 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.0 | 4.4 | GO:0006457 | protein folding(GO:0006457) |
| 0.0 | 0.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.0 | 0.4 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 0.0 | 0.1 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 0.0 | 0.9 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 135.1 | 540.5 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 64.5 | 322.5 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 57.9 | 753.1 | GO:0042555 | MCM complex(GO:0042555) |
| 38.1 | 114.3 | GO:0018444 | translation release factor complex(GO:0018444) |
| 38.1 | 228.4 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 35.3 | 282.7 | GO:0000796 | condensin complex(GO:0000796) |
| 28.7 | 114.9 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 28.6 | 85.9 | GO:0033597 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 28.3 | 113.2 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 28.1 | 140.5 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 27.6 | 137.9 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 26.5 | 291.9 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 23.2 | 69.5 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 21.9 | 131.1 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 21.7 | 86.8 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 21.1 | 63.4 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 21.0 | 83.9 | GO:0000811 | GINS complex(GO:0000811) |
| 20.3 | 182.7 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 20.3 | 142.0 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 20.2 | 60.6 | GO:0031261 | DNA replication preinitiation complex(GO:0031261) |
| 19.9 | 59.8 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 18.8 | 150.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 18.3 | 91.6 | GO:0016589 | NURF complex(GO:0016589) |
| 18.1 | 289.6 | GO:0045120 | pronucleus(GO:0045120) |
| 17.0 | 67.9 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 16.4 | 279.1 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 15.0 | 75.0 | GO:0031523 | Myb complex(GO:0031523) |
| 15.0 | 164.6 | GO:0005638 | lamin filament(GO:0005638) |
| 14.1 | 126.5 | GO:0042382 | paraspeckles(GO:0042382) |
| 10.9 | 76.2 | GO:0001739 | sex chromatin(GO:0001739) |
| 10.7 | 203.6 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 10.7 | 74.8 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 10.5 | 73.3 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 10.3 | 51.6 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 10.1 | 50.7 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 9.6 | 105.5 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 9.4 | 65.6 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 9.2 | 101.5 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 9.1 | 18.1 | GO:0044094 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 8.9 | 80.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 8.7 | 43.6 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 8.7 | 113.1 | GO:0005688 | U6 snRNP(GO:0005688) |
| 8.1 | 40.5 | GO:0089701 | U2AF(GO:0089701) |
| 8.1 | 32.3 | GO:0071942 | XPC complex(GO:0071942) |
| 7.9 | 94.9 | GO:0090543 | Flemming body(GO:0090543) |
| 7.8 | 39.0 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 7.5 | 75.2 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 7.2 | 36.2 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 6.8 | 34.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 6.7 | 73.4 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 6.2 | 118.4 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 6.0 | 54.1 | GO:0070652 | HAUS complex(GO:0070652) |
| 5.9 | 23.6 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 5.7 | 17.1 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 5.6 | 16.7 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 5.6 | 22.2 | GO:0035363 | histone locus body(GO:0035363) |
| 5.5 | 71.9 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 5.4 | 37.5 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 5.1 | 40.8 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 5.1 | 76.1 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 4.9 | 39.2 | GO:0031931 | TORC1 complex(GO:0031931) |
| 4.9 | 9.7 | GO:0000805 | X chromosome(GO:0000805) |
| 4.8 | 33.8 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 4.8 | 9.6 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 4.8 | 33.6 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 4.7 | 23.7 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 4.7 | 23.7 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 4.7 | 32.9 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 4.7 | 32.7 | GO:0032021 | NELF complex(GO:0032021) |
| 4.6 | 105.4 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 4.5 | 72.4 | GO:0005686 | U2 snRNP(GO:0005686) |
| 4.4 | 40.0 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 4.4 | 22.2 | GO:0008274 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 4.4 | 30.9 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 4.4 | 52.8 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 4.3 | 13.0 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 4.2 | 122.9 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 4.1 | 114.6 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 4.0 | 11.9 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 4.0 | 15.8 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 4.0 | 27.7 | GO:0000235 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 3.9 | 19.7 | GO:0033503 | HULC complex(GO:0033503) |
| 3.9 | 100.9 | GO:0043596 | nuclear replication fork(GO:0043596) |
| 3.8 | 38.3 | GO:0032059 | bleb(GO:0032059) |
| 3.8 | 49.4 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 3.7 | 11.2 | GO:0033593 | BRCA2-MAGE-D1 complex(GO:0033593) |
| 3.7 | 171.5 | GO:0090544 | BAF-type complex(GO:0090544) |
| 3.7 | 40.4 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
| 3.6 | 46.6 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 3.6 | 25.0 | GO:0000812 | Swr1 complex(GO:0000812) |
| 3.6 | 28.6 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 3.6 | 35.7 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 3.6 | 120.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 3.5 | 24.4 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 3.4 | 99.8 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
| 3.4 | 13.7 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 3.4 | 311.5 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 3.4 | 40.3 | GO:0030008 | TRAPP complex(GO:0030008) |
| 3.3 | 29.4 | GO:0000938 | GARP complex(GO:0000938) |
| 3.1 | 6.1 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 3.1 | 67.5 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 2.9 | 182.7 | GO:0005876 | spindle microtubule(GO:0005876) |
| 2.8 | 31.1 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 2.8 | 19.7 | GO:0042587 | glycogen granule(GO:0042587) |
| 2.8 | 22.3 | GO:0070187 | telosome(GO:0070187) |
| 2.8 | 218.9 | GO:0000502 | proteasome complex(GO:0000502) |
| 2.7 | 38.0 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 2.7 | 29.3 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 2.6 | 28.5 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 2.5 | 101.4 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 2.5 | 22.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 2.5 | 14.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 2.4 | 7.3 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 2.4 | 9.6 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 2.4 | 14.4 | GO:1990357 | terminal web(GO:1990357) |
| 2.3 | 72.4 | GO:0035267 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 2.3 | 46.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 2.3 | 52.0 | GO:0046930 | pore complex(GO:0046930) |
| 2.2 | 28.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 2.2 | 230.1 | GO:0031970 | organelle envelope lumen(GO:0031970) |
| 2.2 | 158.0 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 2.2 | 38.9 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 2.1 | 19.3 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 2.1 | 64.2 | GO:0030686 | 90S preribosome(GO:0030686) |
| 2.0 | 27.8 | GO:0000124 | SAGA complex(GO:0000124) |
| 2.0 | 35.3 | GO:0051233 | spindle midzone(GO:0051233) |
| 1.9 | 44.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 1.9 | 51.9 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 1.8 | 16.3 | GO:0044327 | dendritic spine head(GO:0044327) |
| 1.8 | 21.6 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 1.8 | 30.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 1.7 | 7.0 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 1.7 | 34.4 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 1.7 | 63.5 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 1.7 | 18.8 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 1.7 | 171.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 1.7 | 97.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 1.7 | 9.9 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 1.7 | 9.9 | GO:0000322 | storage vacuole(GO:0000322) |
| 1.6 | 73.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 1.6 | 24.3 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 1.6 | 9.6 | GO:0034709 | methylosome(GO:0034709) |
| 1.6 | 9.5 | GO:0061617 | MICOS complex(GO:0061617) |
| 1.6 | 14.1 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 1.5 | 4.5 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 1.5 | 13.4 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 1.5 | 8.9 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 1.4 | 228.5 | GO:0000793 | condensed chromosome(GO:0000793) |
| 1.4 | 32.6 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 1.4 | 4.1 | GO:0001652 | granular component(GO:0001652) |
| 1.4 | 13.8 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 1.4 | 101.4 | GO:0070469 | respiratory chain(GO:0070469) |
| 1.3 | 13.4 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 1.3 | 38.9 | GO:0030057 | desmosome(GO:0030057) |
| 1.3 | 19.9 | GO:0035861 | site of double-strand break(GO:0035861) |
| 1.3 | 15.6 | GO:0070938 | contractile ring(GO:0070938) |
| 1.2 | 18.7 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 1.2 | 13.4 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 1.2 | 14.6 | GO:0005915 | zonula adherens(GO:0005915) |
| 1.2 | 63.1 | GO:0031430 | M band(GO:0031430) |
| 1.2 | 171.5 | GO:0034399 | nuclear periphery(GO:0034399) |
| 1.1 | 8.0 | GO:0030891 | VCB complex(GO:0030891) |
| 1.1 | 12.0 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 1.1 | 4.3 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 1.1 | 6.4 | GO:0044754 | autolysosome(GO:0044754) |
| 1.0 | 3.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 1.0 | 16.7 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 1.0 | 29.8 | GO:0031143 | pseudopodium(GO:0031143) |
| 1.0 | 34.6 | GO:0015030 | Cajal body(GO:0015030) |
| 1.0 | 4.9 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 1.0 | 2.9 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.9 | 39.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.8 | 5.9 | GO:0010369 | chromocenter(GO:0010369) |
| 0.8 | 85.3 | GO:0016605 | PML body(GO:0016605) |
| 0.8 | 2.5 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 0.8 | 2.5 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.8 | 23.3 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.8 | 7.2 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.8 | 33.6 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.8 | 2.4 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.8 | 14.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.8 | 39.8 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.8 | 7.8 | GO:0097433 | dense body(GO:0097433) |
| 0.7 | 23.2 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.7 | 15.7 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.7 | 81.8 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.7 | 53.1 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.7 | 15.5 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.7 | 244.1 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.7 | 45.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.7 | 2.8 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
| 0.7 | 2.1 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 0.7 | 165.8 | GO:0019866 | organelle inner membrane(GO:0019866) |
| 0.7 | 55.8 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.7 | 8.6 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.6 | 25.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.6 | 3.0 | GO:0071664 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) |
| 0.6 | 18.4 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.6 | 3.4 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.6 | 14.8 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.5 | 8.2 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.5 | 8.6 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.5 | 124.1 | GO:0043292 | contractile fiber(GO:0043292) |
| 0.5 | 4.3 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.5 | 6.2 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.5 | 9.6 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.5 | 3.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.4 | 11.8 | GO:0032420 | stereocilium(GO:0032420) |
| 0.4 | 1.3 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.4 | 1.7 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.4 | 3.4 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.4 | 4.9 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.4 | 148.7 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.4 | 40.7 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.4 | 50.7 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.4 | 30.1 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.4 | 47.0 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.3 | 5.5 | GO:0031089 | platelet dense granule lumen(GO:0031089) platelet dense granule(GO:0042827) |
| 0.3 | 17.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.3 | 1.9 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.3 | 0.8 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.3 | 6.2 | GO:0002102 | podosome(GO:0002102) |
| 0.3 | 6.4 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.2 | 9.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.2 | 8.4 | GO:0005840 | ribosome(GO:0005840) |
| 0.2 | 2.1 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.2 | 8.4 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.2 | 5.9 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.2 | 3.6 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.2 | 1.1 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.1 | 0.9 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.1 | 17.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 0.1 | GO:0043259 | laminin-10 complex(GO:0043259) |
| 0.1 | 0.7 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.1 | 2.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 1.0 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.1 | 2.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.1 | 0.8 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 3.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 4.3 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 1.5 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.3 | GO:0032591 | dendritic spine membrane(GO:0032591) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 135.1 | 540.5 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 64.5 | 322.5 | GO:0032143 | single thymine insertion binding(GO:0032143) |
| 57.6 | 230.5 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 56.1 | 224.3 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 53.9 | 161.6 | GO:0004638 | phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639) |
| 44.9 | 134.8 | GO:0003896 | DNA primase activity(GO:0003896) |
| 38.5 | 500.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 33.6 | 100.7 | GO:0080023 | 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023) |
| 32.5 | 227.7 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 22.9 | 137.3 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 22.4 | 313.3 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 21.9 | 87.7 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 19.6 | 156.9 | GO:0050733 | RS domain binding(GO:0050733) |
| 19.5 | 58.5 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
| 19.3 | 57.8 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 19.0 | 114.3 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 18.9 | 113.2 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 18.8 | 150.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 18.3 | 54.8 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 17.5 | 105.0 | GO:0036033 | mediator complex binding(GO:0036033) |
| 16.5 | 82.6 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 14.7 | 176.1 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 14.4 | 57.4 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 14.2 | 71.1 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 13.5 | 40.4 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 13.3 | 693.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 12.8 | 12.8 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) |
| 11.9 | 35.7 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 11.3 | 33.9 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 11.2 | 44.7 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 11.1 | 44.4 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 11.0 | 76.8 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 10.9 | 87.3 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 10.5 | 20.9 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 10.4 | 41.6 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 9.9 | 69.1 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 9.9 | 167.7 | GO:0035173 | histone kinase activity(GO:0035173) |
| 9.4 | 65.6 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 9.3 | 102.8 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 9.2 | 64.5 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 9.1 | 54.6 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 8.7 | 260.9 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 8.4 | 25.3 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 8.3 | 50.0 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 8.3 | 33.2 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 7.7 | 30.9 | GO:0004001 | adenosine kinase activity(GO:0004001) |
| 7.7 | 61.3 | GO:0015288 | porin activity(GO:0015288) |
| 7.7 | 61.3 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 7.6 | 45.6 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 7.4 | 52.0 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 7.4 | 22.1 | GO:0016420 | [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) |
| 7.2 | 57.8 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 7.2 | 72.0 | GO:0042731 | PH domain binding(GO:0042731) |
| 7.2 | 28.8 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 6.9 | 41.4 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 6.8 | 225.3 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 6.8 | 67.9 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 6.7 | 40.1 | GO:0016900 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 6.5 | 26.2 | GO:0004477 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 6.5 | 32.5 | GO:0050610 | glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 6.4 | 19.3 | GO:0051717 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) |
| 6.3 | 25.4 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 6.3 | 50.7 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 6.0 | 59.7 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 5.9 | 152.3 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 5.8 | 17.5 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 5.7 | 22.7 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 5.6 | 219.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 5.6 | 78.1 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 5.5 | 87.3 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 5.4 | 254.8 | GO:0061650 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 5.4 | 37.8 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 5.4 | 144.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 5.4 | 26.8 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 5.3 | 63.9 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 5.3 | 52.8 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 5.2 | 15.7 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 5.0 | 20.0 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 5.0 | 14.9 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 5.0 | 74.4 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 4.9 | 64.3 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 4.9 | 34.5 | GO:0005497 | androgen binding(GO:0005497) |
| 4.9 | 14.6 | GO:0034736 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 4.8 | 19.1 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 4.7 | 9.5 | GO:0070990 | snRNP binding(GO:0070990) |
| 4.7 | 14.1 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 4.7 | 107.6 | GO:0005537 | mannose binding(GO:0005537) |
| 4.5 | 85.7 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 4.5 | 35.9 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 4.4 | 111.1 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 4.4 | 26.4 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 4.3 | 129.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 4.2 | 25.1 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 4.2 | 20.8 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 4.1 | 81.9 | GO:0031491 | nucleosome binding(GO:0031491) |
| 4.1 | 20.3 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 4.0 | 122.9 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 3.9 | 50.9 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 3.8 | 23.0 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 3.8 | 30.3 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 3.8 | 15.1 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 3.7 | 100.4 | GO:0043274 | phospholipase binding(GO:0043274) |
| 3.7 | 14.8 | GO:0043515 | kinetochore binding(GO:0043515) |
| 3.6 | 57.4 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 3.6 | 17.9 | GO:0034597 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 3.6 | 14.3 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 3.4 | 13.7 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 3.3 | 23.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 3.3 | 36.3 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 3.3 | 13.0 | GO:0033823 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 3.2 | 67.5 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 3.2 | 9.6 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 3.1 | 34.5 | GO:0039706 | co-receptor binding(GO:0039706) |
| 3.1 | 25.1 | GO:0046790 | virion binding(GO:0046790) |
| 3.1 | 43.7 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 3.1 | 61.7 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 3.1 | 64.6 | GO:0004532 | exoribonuclease activity(GO:0004532) |
| 3.1 | 70.7 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 3.0 | 14.9 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 2.9 | 53.1 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 2.9 | 114.7 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 2.9 | 79.0 | GO:0008483 | transaminase activity(GO:0008483) |
| 2.9 | 20.5 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 2.9 | 5.8 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 2.9 | 66.3 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 2.8 | 30.7 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 2.7 | 30.2 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 2.6 | 15.8 | GO:0030957 | Tat protein binding(GO:0030957) |
| 2.6 | 10.5 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 2.5 | 28.0 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 2.4 | 389.1 | GO:0042393 | histone binding(GO:0042393) |
| 2.4 | 9.8 | GO:0004335 | galactokinase activity(GO:0004335) |
| 2.3 | 11.7 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 2.3 | 51.1 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 2.3 | 111.3 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 2.3 | 13.9 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 2.3 | 6.9 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 2.2 | 19.9 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 2.2 | 13.2 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 2.2 | 6.6 | GO:0016154 | thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154) |
| 2.2 | 70.0 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 2.2 | 6.5 | GO:0055100 | adiponectin binding(GO:0055100) |
| 2.2 | 15.1 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 2.2 | 47.3 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 2.1 | 59.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 2.1 | 16.5 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 2.0 | 12.2 | GO:0004645 | phosphorylase activity(GO:0004645) |
| 2.0 | 14.1 | GO:0000150 | recombinase activity(GO:0000150) |
| 2.0 | 110.3 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 2.0 | 41.9 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 2.0 | 95.3 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 2.0 | 5.9 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 2.0 | 175.4 | GO:0004386 | helicase activity(GO:0004386) |
| 2.0 | 15.7 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 2.0 | 54.9 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 1.9 | 11.5 | GO:0000182 | rDNA binding(GO:0000182) |
| 1.9 | 53.6 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 1.9 | 24.3 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 1.9 | 129.9 | GO:0070888 | E-box binding(GO:0070888) |
| 1.8 | 106.1 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 1.8 | 132.4 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 1.8 | 32.1 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 1.8 | 14.2 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 1.8 | 5.3 | GO:0098847 | sequence-specific single stranded DNA binding(GO:0098847) |
| 1.7 | 10.4 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 1.7 | 23.7 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 1.7 | 10.1 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 1.7 | 13.4 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 1.7 | 5.0 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 1.6 | 44.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 1.6 | 6.4 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 1.6 | 17.5 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 1.6 | 7.9 | GO:0047280 | nicotinamide phosphoribosyltransferase activity(GO:0047280) |
| 1.6 | 9.4 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 1.6 | 4.7 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 1.5 | 306.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.5 | 4.6 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
| 1.5 | 13.4 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 1.5 | 28.3 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 1.4 | 12.9 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 1.4 | 15.7 | GO:0038132 | neuregulin binding(GO:0038132) |
| 1.4 | 4.3 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 1.4 | 5.6 | GO:0016972 | flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972) |
| 1.4 | 47.9 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 1.4 | 67.5 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 1.4 | 4.2 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 1.4 | 7.0 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 1.4 | 66.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 1.4 | 59.8 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 1.4 | 10.8 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 1.3 | 34.8 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 1.3 | 6.6 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 1.3 | 15.4 | GO:0031386 | protein tag(GO:0031386) |
| 1.2 | 68.8 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 1.2 | 39.3 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 1.2 | 7.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 1.2 | 16.6 | GO:0000339 | RNA cap binding(GO:0000339) |
| 1.2 | 16.5 | GO:0048156 | tau protein binding(GO:0048156) |
| 1.2 | 51.6 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 1.1 | 11.2 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 1.1 | 59.5 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 1.1 | 5.5 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 1.1 | 5.4 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 1.1 | 5.3 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 1.0 | 13.6 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 1.0 | 30.3 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 1.0 | 18.5 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 1.0 | 75.0 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 1.0 | 8.0 | GO:0031996 | thioesterase binding(GO:0031996) |
| 1.0 | 7.0 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.9 | 4.7 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.9 | 25.5 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.9 | 71.2 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.9 | 3.7 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 0.9 | 3.7 | GO:0032810 | sterol response element binding(GO:0032810) |
| 0.9 | 51.3 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
| 0.9 | 9.8 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.9 | 24.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.9 | 11.1 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.8 | 5.1 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.8 | 13.5 | GO:0070513 | death domain binding(GO:0070513) |
| 0.8 | 7.6 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.8 | 157.1 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.8 | 10.1 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.8 | 63.2 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.8 | 5.0 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.8 | 17.5 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.8 | 2.4 | GO:0035529 | phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529) |
| 0.8 | 6.4 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.8 | 3.2 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.8 | 13.6 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.8 | 31.9 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.8 | 7.8 | GO:0034594 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
| 0.8 | 40.3 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 0.8 | 17.0 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.8 | 1.5 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) |
| 0.7 | 4.5 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.7 | 24.3 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.7 | 5.7 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.7 | 2.1 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.7 | 7.5 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.7 | 28.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.7 | 18.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.7 | 17.5 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.7 | 249.8 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.7 | 2.0 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.6 | 7.5 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.6 | 15.0 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.6 | 22.5 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.6 | 7.3 | GO:0004549 | tRNA-specific ribonuclease activity(GO:0004549) |
| 0.5 | 46.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.5 | 6.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.5 | 41.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.5 | 20.3 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.5 | 4.5 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.5 | 4.1 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) aryl hydrocarbon receptor binding(GO:0017162) |
| 0.4 | 5.6 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.4 | 27.9 | GO:0016651 | oxidoreductase activity, acting on NAD(P)H(GO:0016651) |
| 0.4 | 2.0 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.4 | 4.9 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.4 | 1.6 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.4 | 41.3 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.4 | 13.5 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.4 | 64.4 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.4 | 6.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.4 | 3.9 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.4 | 9.8 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.3 | 4.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.3 | 4.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.3 | 4.2 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.3 | 29.1 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.3 | 5.4 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.3 | 2.5 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.3 | 1.9 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.3 | 13.0 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.3 | 12.5 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.2 | 0.7 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.2 | 2.1 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.2 | 3.4 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.2 | 13.5 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.2 | 2.2 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.2 | 1.3 | GO:0015350 | reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350) |
| 0.2 | 3.4 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.2 | 4.6 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.2 | 3.3 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.2 | 10.3 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.2 | 1.4 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.2 | 1.0 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.2 | 1.8 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.2 | 4.1 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.2 | 55.2 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.2 | 1.7 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.2 | 1.6 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.2 | 8.4 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.2 | 3.9 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.2 | 21.0 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.2 | 1.4 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.1 | 0.9 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 1.9 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 2.3 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.1 | 0.8 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923) |
| 0.1 | 3.2 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 8.8 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.1 | 2.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 1.2 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.1 | 0.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 84.0 | GO:0003723 | RNA binding(GO:0003723) |
| 0.1 | 0.9 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.1 | 0.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 1.0 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 3.5 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 1.6 | GO:0008374 | O-acyltransferase activity(GO:0008374) |
| 0.1 | 5.4 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.7 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.0 | 3.7 | GO:0008237 | metallopeptidase activity(GO:0008237) |
| 0.0 | 0.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 0.2 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.7 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.2 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 15.9 | 126.8 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 15.6 | 1859.2 | PID E2F PATHWAY | E2F transcription factor network |
| 15.3 | 306.2 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 10.2 | 142.7 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 10.2 | 568.6 | PID ATR PATHWAY | ATR signaling pathway |
| 6.0 | 24.2 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 5.4 | 189.7 | PID BARD1 PATHWAY | BARD1 signaling events |
| 5.0 | 129.3 | PID ATM PATHWAY | ATM pathway |
| 4.8 | 190.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 4.3 | 4.3 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 4.0 | 230.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 3.1 | 12.6 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 2.9 | 46.0 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 2.7 | 54.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 2.7 | 94.9 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 2.4 | 460.5 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 2.4 | 37.9 | PID MYC PATHWAY | C-MYC pathway |
| 2.3 | 109.4 | PID PLK1 PATHWAY | PLK1 signaling events |
| 2.3 | 152.4 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 2.3 | 237.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 2.2 | 21.7 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 2.1 | 191.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 2.0 | 39.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 1.9 | 1.9 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 1.7 | 76.7 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 1.6 | 172.4 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 1.6 | 98.4 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 1.5 | 39.9 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 1.5 | 52.9 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 1.5 | 54.6 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 1.3 | 14.6 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 1.3 | 17.8 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 1.2 | 15.7 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 1.1 | 7.8 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 1.0 | 64.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 1.0 | 40.4 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.9 | 31.0 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.9 | 4.5 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.8 | 22.9 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.8 | 40.4 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.8 | 23.9 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.7 | 4.9 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.7 | 8.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.7 | 14.5 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.6 | 27.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.6 | 34.7 | PID P73PATHWAY | p73 transcription factor network |
| 0.5 | 8.0 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.5 | 20.3 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.5 | 8.6 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.5 | 12.3 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.5 | 19.6 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.4 | 14.3 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.4 | 6.4 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.4 | 12.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.4 | 12.6 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.3 | 5.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.3 | 10.8 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.2 | 18.0 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.2 | 1.4 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.2 | 2.2 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 6.3 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.1 | 3.8 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.1 | 2.1 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 4.2 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 4.1 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 2.6 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.1 | 3.1 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 4.5 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 2.3 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 1.1 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.5 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.0 | 0.7 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.5 | PID CDC42 PATHWAY | CDC42 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 59.4 | 890.6 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 32.5 | 974.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 29.3 | 381.1 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 21.9 | 328.5 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 15.9 | 238.7 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 15.0 | 135.1 | REACTOME DNA STRAND ELONGATION | Genes involved in DNA strand elongation |
| 13.5 | 202.4 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 12.8 | 12.8 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 12.0 | 36.0 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 9.2 | 202.1 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 8.9 | 293.8 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 8.5 | 161.9 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 8.5 | 253.7 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 8.2 | 163.4 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 8.1 | 242.6 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 8.0 | 246.7 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 7.3 | 160.9 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 7.1 | 99.5 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 6.9 | 69.1 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 5.8 | 86.8 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 5.6 | 860.4 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 5.0 | 75.6 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 4.7 | 109.1 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 4.7 | 52.0 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 4.6 | 60.1 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 4.6 | 445.3 | REACTOME S PHASE | Genes involved in S Phase |
| 4.4 | 31.0 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 4.3 | 46.8 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 4.1 | 143.5 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 4.0 | 132.4 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 3.7 | 191.2 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 3.6 | 89.3 | REACTOME GLOBAL GENOMIC NER GG NER | Genes involved in Global Genomic NER (GG-NER) |
| 3.5 | 59.9 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 3.5 | 97.2 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 3.4 | 58.5 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 3.4 | 60.4 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 3.3 | 97.8 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 3.2 | 31.7 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 3.1 | 6.2 | REACTOME CELL CELL COMMUNICATION | Genes involved in Cell-Cell communication |
| 3.1 | 15.3 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 3.0 | 89.4 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 2.9 | 130.4 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 2.8 | 22.3 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 2.8 | 96.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 2.8 | 22.0 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 2.7 | 96.6 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 2.7 | 99.2 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 2.7 | 40.1 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 2.7 | 42.7 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 2.6 | 28.7 | REACTOME CHROMOSOME MAINTENANCE | Genes involved in Chromosome Maintenance |
| 2.6 | 53.7 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 2.5 | 42.9 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 2.4 | 161.0 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 2.4 | 76.7 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 2.4 | 367.1 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 2.3 | 78.9 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 2.3 | 498.1 | REACTOME TRANSLATION | Genes involved in Translation |
| 2.1 | 45.1 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 2.0 | 28.2 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 1.9 | 38.8 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 1.8 | 33.2 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 1.8 | 142.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 1.8 | 50.1 | REACTOME KINESINS | Genes involved in Kinesins |
| 1.7 | 97.4 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 1.5 | 19.4 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 1.5 | 43.6 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 1.4 | 31.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 1.4 | 23.8 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 1.3 | 46.4 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 1.3 | 45.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 1.2 | 29.7 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 1.1 | 32.2 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 1.1 | 54.0 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 1.0 | 29.8 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 1.0 | 8.9 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 1.0 | 8.8 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 1.0 | 12.7 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.9 | 14.1 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.9 | 47.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.8 | 100.3 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.8 | 6.7 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.7 | 12.7 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.7 | 1.4 | REACTOME PI3K CASCADE | Genes involved in PI3K Cascade |
| 0.7 | 20.0 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.6 | 11.0 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.6 | 33.0 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.6 | 1.2 | REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION | Genes involved in RORA Activates Circadian Expression |
| 0.5 | 9.2 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.5 | 16.5 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.5 | 6.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.5 | 17.2 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.5 | 14.1 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.4 | 6.7 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.4 | 10.8 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.4 | 24.0 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.4 | 19.0 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.4 | 2.2 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.3 | 14.2 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.3 | 5.9 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.3 | 2.4 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.3 | 2.1 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.2 | 16.5 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.2 | 2.1 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.2 | 6.4 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.2 | 5.5 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.2 | 0.7 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.2 | 2.8 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.2 | 4.1 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.2 | 4.2 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 4.5 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 2.2 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 0.9 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.1 | 3.9 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 1.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 2.0 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 0.9 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 1.1 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 0.6 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 1.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 2.5 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 1.1 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.9 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 2.2 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |