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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EBF3

Z-value: 0.89

Motif logo

Transcription factors associated with EBF3

Gene Symbol Gene ID Gene Info
ENSG00000108001.16 EBF3

Activity profile of EBF3 motif

Sorted Z-values of EBF3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EBF3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_153544997 12.63 ENST00000368715.5
S100 calcium binding protein A4
chr8_+_22578735 9.68 ENST00000339162.11
ENST00000308354.11
PDZ and LIM domain 2
chr19_-_2042066 8.70 ENST00000591588.1
ENST00000591142.5
MAPK interacting serine/threonine kinase 2
chr8_+_22579100 8.36 ENST00000452226.5
ENST00000397760.8
PDZ and LIM domain 2
chr16_+_32066065 8.08 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr7_-_101237760 7.82 ENST00000412417.1
ENST00000414035.5
claudin 15
chr8_+_22579139 7.50 ENST00000397761.6
PDZ and LIM domain 2
chr19_-_45322867 7.31 ENST00000221476.4
creatine kinase, M-type
chr1_-_112704921 7.21 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr1_-_153550083 6.94 ENST00000368714.1
S100 calcium binding protein A4
chr3_-_46882106 6.57 ENST00000662933.1
myosin light chain 3
chr7_+_76303547 6.55 ENST00000429938.1
heat shock protein family B (small) member 1
chr18_+_11981488 6.40 ENST00000269159.8
inositol monophosphatase 2
chr1_-_154970735 6.25 ENST00000368445.9
ENST00000448116.7
ENST00000368449.8
SHC adaptor protein 1
chr2_-_89143133 6.21 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr14_-_106470788 6.15 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr7_-_138001794 6.10 ENST00000616381.4
ENST00000620715.4
cAMP responsive element binding protein 3 like 2
chr14_-_106269133 6.05 ENST00000390609.3
immunoglobulin heavy variable 3-23
chr14_-_106117159 6.01 ENST00000390601.3
immunoglobulin heavy variable 3-11
chr19_+_48900305 6.00 ENST00000405315.9
ENST00000407032.5
ENST00000452087.5
ENST00000411700.5
nucleobindin 1
chr14_-_106538331 5.99 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr7_-_138002017 5.97 ENST00000452463.5
ENST00000456390.5
ENST00000330387.11
cAMP responsive element binding protein 3 like 2
chr14_-_106235582 5.83 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr6_-_7910776 5.75 ENST00000379757.9
thioredoxin domain containing 5
chr8_+_22589240 5.56 ENST00000450780.6
ENST00000430850.6
ENST00000447849.2
ENST00000614502.4
ENST00000443561.3
novel protein
PDZ and LIM domain 2
chr15_-_19988117 5.55 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr5_-_172771187 5.44 ENST00000239223.4
dual specificity phosphatase 1
chr22_-_37244237 5.26 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr2_-_89027700 5.18 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr3_-_142889075 5.15 ENST00000295992.8
procollagen C-endopeptidase enhancer 2
chr14_-_106088573 5.11 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr16_+_33802683 5.10 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr1_+_153357846 5.05 ENST00000368738.4
S100 calcium binding protein A9
chr12_+_119178920 4.70 ENST00000281938.7
heat shock protein family B (small) member 8
chr14_-_106335613 4.70 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr17_+_42289213 4.65 ENST00000677301.1
signal transducer and activator of transcription 5A
chr3_-_142889156 4.55 ENST00000648195.1
procollagen C-endopeptidase enhancer 2
chr10_+_92689946 4.49 ENST00000282728.10
hematopoietically expressed homeobox
chr14_+_105486311 4.44 ENST00000330233.11
cysteine rich protein 1
chr1_+_32292067 4.42 ENST00000373548.8
ENST00000428704.1
histone deacetylase 1
chr2_-_218286763 4.42 ENST00000444881.5
transmembrane BAX inhibitor motif containing 1
chr11_+_1839452 4.40 ENST00000381906.5
troponin I2, fast skeletal type
chr14_-_105588322 4.38 ENST00000497872.4
ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr3_-_142888896 4.35 ENST00000485766.1
procollagen C-endopeptidase enhancer 2
chr11_+_75562242 4.32 ENST00000526397.5
ENST00000529643.1
ENST00000525492.5
ENST00000530284.5
ENST00000358171.8
serpin family H member 1
chr6_-_106974721 4.30 ENST00000606017.2
ENST00000620405.1
CD24 molecule
chr7_-_101237791 4.27 ENST00000308344.10
claudin 15
chr14_-_106062670 4.18 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr2_+_119223815 4.18 ENST00000393106.6
ENST00000393110.7
ENST00000409811.5
ENST00000393107.2
STEAP3 metalloreductase
chr11_+_75562056 4.16 ENST00000533603.5
serpin family H member 1
chr4_-_89837076 4.14 ENST00000506691.1
synuclein alpha
chr12_-_54300974 4.08 ENST00000435572.7
ENST00000553070.5
nuclear factor, erythroid 2
chr11_+_1838970 4.05 ENST00000381911.6
troponin I2, fast skeletal type
chr22_+_23966880 4.04 ENST00000215770.6
D-dopachrome tautomerase like
chr19_+_49677228 4.02 ENST00000454376.7
ENST00000524771.5
protein arginine methyltransferase 1
chr11_-_67353503 4.02 ENST00000539074.1
ENST00000530584.5
ENST00000531239.2
ENST00000312419.8
ENST00000529704.5
DNA polymerase delta 4, accessory subunit
chr12_+_121803991 3.99 ENST00000604567.6
ENST00000542440.5
SET domain containing 1B, histone lysine methyltransferase
chr14_+_105486867 3.98 ENST00000409393.6
ENST00000392531.4
cysteine rich protein 1
chr3_-_46882165 3.96 ENST00000431168.1
ENST00000654597.1
myosin light chain 3
chr12_-_106247950 3.96 ENST00000378026.5
cytoskeleton associated protein 4
chr1_+_26543106 3.95 ENST00000530003.5
ribosomal protein S6 kinase A1
chr3_+_38138478 3.92 ENST00000396334.8
ENST00000417037.8
ENST00000652213.1
ENST00000650112.2
ENST00000651800.2
ENST00000421516.3
ENST00000650905.2
MYD88 innate immune signal transduction adaptor
chr19_-_39840671 3.91 ENST00000597224.5
fibrillarin
chr19_-_3061403 3.88 ENST00000586839.1
TLE family member 5, transcriptional modulator
chr6_+_31587185 3.85 ENST00000376092.7
ENST00000376086.7
ENST00000303757.12
ENST00000376093.6
leukocyte specific transcript 1
chr6_+_31587268 3.84 ENST00000396101.7
ENST00000490742.5
leukocyte specific transcript 1
chr16_+_69924984 3.81 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr11_+_64234569 3.78 ENST00000309422.7
ENST00000426086.3
vascular endothelial growth factor B
chr7_-_44141285 3.77 ENST00000458240.5
ENST00000223364.7
myosin light chain 7
chr11_+_75562274 3.75 ENST00000532356.5
ENST00000524558.5
serpin family H member 1
chr19_+_49677055 3.74 ENST00000534465.6
ENST00000391851.8
ENST00000610806.4
protein arginine methyltransferase 1
chr7_-_44141074 3.72 ENST00000457314.5
ENST00000447951.1
ENST00000431007.1
myosin light chain 7
chr11_+_1839602 3.70 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr19_+_40601342 3.62 ENST00000396819.8
latent transforming growth factor beta binding protein 4
chr22_+_22887780 3.61 ENST00000532223.2
ENST00000526893.6
ENST00000531372.1
immunoglobulin lambda like polypeptide 5
chr12_+_119178953 3.59 ENST00000674542.1
heat shock protein family B (small) member 8
chr17_-_82273424 3.58 ENST00000398519.9
ENST00000580446.1
casein kinase 1 delta
chr2_-_173965356 3.56 ENST00000310015.12
Sp3 transcription factor
chr11_-_72721908 3.56 ENST00000426523.5
ENST00000429686.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_+_77538059 3.55 ENST00000435495.6
protein tyrosine phosphatase non-receptor type 12
chr7_+_100867379 3.50 ENST00000200457.9
ENST00000619988.4
thyroid hormone receptor interactor 6
chr19_+_45507470 3.48 ENST00000245932.11
ENST00000592139.1
ENST00000590603.1
vasodilator stimulated phosphoprotein
chr2_+_87338511 3.33 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr5_+_155013755 3.25 ENST00000435029.6
kinesin family member 4B
chr9_+_132978687 3.23 ENST00000372122.4
ENST00000372123.5
growth factor independent 1B transcriptional repressor
chr3_-_190122317 3.18 ENST00000427335.6
prolyl 3-hydroxylase 2
chr4_-_139302516 3.18 ENST00000394228.5
ENST00000539387.5
NADH:ubiquinone oxidoreductase subunit C1
chr22_-_19479160 3.15 ENST00000399523.5
ENST00000421968.6
ENST00000263202.15
ENST00000447868.5
ubiquitin recognition factor in ER associated degradation 1
chr22_-_23980469 3.12 ENST00000404092.5
novel protein, AP000351.4-DDT readtrhough
chr6_+_32969345 3.10 ENST00000678250.1
bromodomain containing 2
chr9_+_132978651 3.09 ENST00000636137.1
growth factor independent 1B transcriptional repressor
chr3_-_49132994 3.06 ENST00000305544.9
ENST00000494831.1
ENST00000418109.5
laminin subunit beta 2
chr4_-_139302460 3.06 ENST00000394223.2
ENST00000676245.1
NADH:ubiquinone oxidoreductase subunit C1
chr15_+_73926443 3.05 ENST00000261921.8
lysyl oxidase like 1
chr7_-_150632333 3.04 ENST00000493969.2
ENST00000328902.9
GTPase, IMAP family member 6
chr8_+_144358557 3.02 ENST00000530047.5
ENST00000527078.6
ENST00000674870.1
ENST00000526338.7
ENST00000402965.5
ENST00000329994.7
ENST00000526752.3
ENST00000533662.2
ENST00000534725.6
ENST00000674929.1
ENST00000675597.1
ENST00000643944.2
ENST00000675121.1
solute carrier family 52 member 2
chr7_-_150632644 3.01 ENST00000618759.4
GTPase, IMAP family member 6
chr7_-_133082032 3.00 ENST00000448878.6
ENST00000262570.10
coiled-coil-helix-coiled-coil-helix domain containing 3
chr22_-_23974441 2.99 ENST00000398344.9
ENST00000403754.7
ENST00000430101.2
D-dopachrome tautomerase
chrX_+_48786578 2.98 ENST00000376670.9
GATA binding protein 1
chrX_+_70290077 2.94 ENST00000374403.4
kinesin family member 4A
chr19_+_12938598 2.94 ENST00000586760.2
ENST00000316448.10
ENST00000588454.6
calreticulin
chr1_+_153775357 2.93 ENST00000624995.4
solute carrier family 27 member 3
chrX_+_48786562 2.93 ENST00000651144.1
ENST00000376665.4
GATA binding protein 1
chr7_-_6484057 2.88 ENST00000490996.1
ENST00000258739.9
ENST00000436575.5
KDEL endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase beta
chr9_-_127873462 2.86 ENST00000223836.10
adenylate kinase 1
chr15_+_63042632 2.86 ENST00000288398.10
ENST00000358278.7
ENST00000610733.1
ENST00000403994.9
ENST00000357980.9
ENST00000559556.5
ENST00000267996.11
ENST00000559397.6
ENST00000561266.6
ENST00000560970.6
tropomyosin 1
chr6_-_24877262 2.86 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr3_+_184300564 2.82 ENST00000435761.5
ENST00000439383.5
proteasome 26S subunit, non-ATPase 2
chrX_-_154409278 2.81 ENST00000369808.7
deoxyribonuclease 1 like 1
chr14_-_24195570 2.79 ENST00000530468.5
ENST00000528010.1
ENST00000396854.8
ENST00000524835.5
ENST00000525592.1
transmembrane 9 superfamily member 1
chr22_+_21642287 2.78 ENST00000248958.5
stromal cell derived factor 2 like 1
chr16_-_33845229 2.78 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr17_+_41819201 2.73 ENST00000455106.1
FKBP prolyl isomerase 10
chr14_-_24195334 2.72 ENST00000530563.1
ENST00000528895.5
ENST00000528669.5
ENST00000532632.1
ENST00000261789.9
transmembrane 9 superfamily member 1
chr10_-_13972355 2.72 ENST00000264546.10
FERM domain containing 4A
chr22_-_43015133 2.70 ENST00000453643.5
ENST00000263246.8
protein kinase C and casein kinase substrate in neurons 2
chrX_-_154409246 2.70 ENST00000369807.6
deoxyribonuclease 1 like 1
chr1_+_109656322 2.66 ENST00000369833.5
ENST00000336075.6
ENST00000638994.1
glutathione S-transferase mu 4
chr17_-_80220325 2.65 ENST00000326317.11
ENST00000570427.1
ENST00000570923.1
N-sulfoglucosamine sulfohydrolase
chr5_-_181242195 2.63 ENST00000502905.5
receptor for activated C kinase 1
chrX_+_155881306 2.58 ENST00000286448.12
ENST00000262640.11
ENST00000460621.6
vesicle associated membrane protein 7
chrX_+_154429092 2.54 ENST00000619046.5
ATPase H+ transporting accessory protein 1
chr2_+_85695368 2.50 ENST00000526018.1
granulysin
chr16_+_67199104 2.45 ENST00000360833.6
ENST00000652269.1
ENST00000393997.8
engulfment and cell motility 3
chr11_-_67443785 2.45 ENST00000393893.5
ENST00000545016.2
coronin 1B
chr6_-_10419638 2.43 ENST00000319516.8
transcription factor AP-2 alpha
chr14_-_106130061 2.43 ENST00000390602.3
immunoglobulin heavy variable 3-13
chr5_-_181242236 2.42 ENST00000507756.5
receptor for activated C kinase 1
chr19_+_33374312 2.41 ENST00000585933.2
CCAAT enhancer binding protein gamma
chr2_-_187513641 2.39 ENST00000392365.5
ENST00000435414.5
tissue factor pathway inhibitor
chr7_-_101237827 2.36 ENST00000611078.4
claudin 15
chr11_-_65614195 2.36 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr7_-_100642721 2.35 ENST00000462107.1
transferrin receptor 2
chr18_+_31498168 2.34 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr1_+_2556361 2.33 ENST00000355716.5
TNF receptor superfamily member 14
chr6_-_46015812 2.30 ENST00000544153.3
ENST00000339561.12
chloride intracellular channel 5
chr22_+_39502320 2.29 ENST00000404569.5
mitochondrial elongation factor 1
chr3_-_88059042 2.27 ENST00000309534.10
CGG triplet repeat binding protein 1
chr2_-_218270099 2.27 ENST00000248450.9
ENST00000444053.5
angio associated migratory cell protein
chr9_+_125747345 2.26 ENST00000342287.9
ENST00000373489.10
ENST00000373487.8
PBX homeobox 3
chr14_-_106360320 2.26 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr7_+_77538027 2.25 ENST00000433369.6
ENST00000415482.6
protein tyrosine phosphatase non-receptor type 12
chr17_-_82065525 2.25 ENST00000354321.11
dihydrouridine synthase 1 like
chr3_+_194136138 2.24 ENST00000232424.4
hes family bHLH transcription factor 1
chr11_+_20363685 2.20 ENST00000530266.5
ENST00000451739.7
ENST00000421577.6
ENST00000443524.6
ENST00000419348.6
HIV-1 Tat interactive protein 2
chr19_-_48390847 2.19 ENST00000597017.5
KDEL endoplasmic reticulum protein retention receptor 1
chr17_+_75667315 2.19 ENST00000584667.6
ENST00000355423.7
SAP30 binding protein
chr3_+_16884942 2.15 ENST00000615277.5
phospholipase C like 2
chr11_-_6619353 2.14 ENST00000642892.1
ENST00000645620.1
ENST00000533371.6
ENST00000647152.1
ENST00000644810.1
ENST00000299427.12
ENST00000682424.1
ENST00000644218.1
ENST00000528657.2
ENST00000531754.2
tripeptidyl peptidase 1
chr6_+_32969165 2.13 ENST00000496118.2
ENST00000449085.4
bromodomain containing 2
chr5_+_69093943 2.13 ENST00000621204.4
solute carrier family 30 member 5
chr3_-_52239082 2.09 ENST00000499914.2
ENST00000678838.1
ENST00000305533.10
ENST00000678330.1
twinfilin actin binding protein 2
chr21_+_36135071 2.09 ENST00000290354.6
carbonyl reductase 3
chr16_+_32995048 2.09 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr16_-_28495519 2.07 ENST00000569430.7
CLN3 lysosomal/endosomal transmembrane protein, battenin
chr11_+_60455839 2.07 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chr3_-_149576203 2.07 ENST00000472417.1
WW domain containing transcription regulator 1
chr20_-_50115935 2.05 ENST00000340309.7
ENST00000415862.6
ENST00000371677.7
ubiquitin conjugating enzyme E2 V1
chr8_-_19602484 2.05 ENST00000454498.6
ENST00000520003.5
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr5_+_179559692 2.05 ENST00000437570.6
ENST00000393438.6
RUN and FYVE domain containing 1
chr3_-_88058928 2.04 ENST00000482016.6
CGG triplet repeat binding protein 1
chr19_+_2476118 2.02 ENST00000215631.9
ENST00000587345.1
growth arrest and DNA damage inducible beta
chr9_+_125748175 2.02 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr1_-_165445220 1.99 ENST00000619224.1
retinoid X receptor gamma
chrX_+_136147465 1.96 ENST00000651929.2
four and a half LIM domains 1
chr1_-_116667668 1.93 ENST00000369486.8
ENST00000369483.5
immunoglobulin superfamily member 3
chr21_-_14658812 1.92 ENST00000647101.1
SAM domain, SH3 domain and nuclear localization signals 1
chr5_+_154190725 1.92 ENST00000425427.6
ENST00000297107.11
polypeptide N-acetylgalactosaminyltransferase 10
chr12_-_663431 1.91 ENST00000305108.10
ninjurin 2
chr10_+_11742361 1.91 ENST00000379215.9
ENST00000420401.5
enoyl-CoA hydratase domain containing 3
chr14_+_18967434 1.89 ENST00000547889.6
POTE ankyrin domain family member M
chr4_-_128287785 1.88 ENST00000296425.10
progesterone receptor membrane component 2
chrX_+_101623121 1.88 ENST00000491568.6
ENST00000479298.5
ENST00000471229.7
armadillo repeat containing X-linked 3
chr14_-_65102468 1.87 ENST00000555932.5
ENST00000284165.10
ENST00000358402.8
ENST00000246163.2
ENST00000358664.9
ENST00000556979.5
ENST00000555667.5
ENST00000557746.5
ENST00000556443.5
ENST00000618858.4
ENST00000557277.5
ENST00000556892.5
MYC associated factor X
chr19_+_41877267 1.87 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79a molecule
chr17_-_82065783 1.83 ENST00000578907.5
ENST00000577907.1
ENST00000578176.5
ENST00000306796.10
ENST00000582529.5
dihydrouridine synthase 1 like
chr19_+_47309853 1.82 ENST00000355085.4
complement C5a receptor 1
chr6_+_31587049 1.82 ENST00000376089.6
ENST00000396112.6
leukocyte specific transcript 1
chr18_-_51197671 1.82 ENST00000406189.4
mex-3 RNA binding family member C
chrX_-_10677720 1.82 ENST00000453318.6
midline 1
chr14_+_24120956 1.80 ENST00000558325.2
novel protein
chr3_+_141368497 1.79 ENST00000321464.7
zinc finger and BTB domain containing 38
chr1_+_161749762 1.79 ENST00000367943.5
dual specificity phosphatase 12
chr12_-_663572 1.76 ENST00000662884.1
ninjurin 2
chr3_-_63863791 1.76 ENST00000464327.2
ENST00000295899.10
ENST00000469584.5
THO complex 7
chr10_+_97572493 1.74 ENST00000307518.9
ENST00000298808.9
ankyrin repeat domain 2
chr8_-_28889958 1.74 ENST00000521022.6
integrator complex subunit 9
chr16_+_67199509 1.74 ENST00000477898.5
engulfment and cell motility 3
chr6_+_31587002 1.73 ENST00000376090.6
leukocyte specific transcript 1
chr17_+_42288429 1.73 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chrX_+_136147525 1.72 ENST00000652745.1
ENST00000627578.2
ENST00000652457.1
ENST00000394155.8
ENST00000618438.4
four and a half LIM domains 1
chr11_-_67443459 1.71 ENST00000341356.10
ENST00000627576.2
coronin 1B
chr1_+_26826682 1.70 ENST00000374142.9
zinc finger DHHC-type palmitoyltransferase 18
chr14_+_24161257 1.69 ENST00000396864.8
ENST00000557894.5
ENST00000559284.5
ENST00000560275.5
interferon regulatory factor 9
chr12_-_51270274 1.69 ENST00000605627.1
small cell adhesion glycoprotein
chr1_-_154192058 1.68 ENST00000271850.11
ENST00000368530.7
ENST00000651641.1
tropomyosin 3
chr17_+_75667390 1.67 ENST00000583536.5
SAP30 binding protein
chr17_-_82059973 1.66 ENST00000577574.5
dihydrouridine synthase 1 like
chr22_-_37244417 1.65 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
2.0 5.9 GO:0030221 basophil differentiation(GO:0030221)
1.6 6.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
1.5 4.5 GO:0061011 hepatic duct development(GO:0061011)
1.5 11.8 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.4 7.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
1.3 3.9 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
1.3 5.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.1 7.8 GO:0045653 histone H4-R3 methylation(GO:0043985) negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.1 4.3 GO:0032599 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
1.1 6.4 GO:0006021 inositol biosynthetic process(GO:0006021)
1.0 4.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
1.0 3.1 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
1.0 10.7 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
1.0 2.9 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
1.0 5.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.9 3.7 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.9 13.7 GO:0006600 creatine metabolic process(GO:0006600)
0.9 1.8 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.9 4.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.9 3.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.9 2.6 GO:1903778 positive regulation of histamine secretion by mast cell(GO:1903595) protein localization to vacuolar membrane(GO:1903778)
0.9 4.3 GO:0007386 compartment pattern specification(GO:0007386)
0.8 4.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.8 2.5 GO:0002818 intracellular defense response(GO:0002818)
0.8 4.9 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.8 6.5 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.8 3.9 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.8 7.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.7 2.2 GO:0061009 midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164) common bile duct development(GO:0061009)
0.7 2.9 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.7 2.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.7 2.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.7 2.0 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.7 2.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.6 5.8 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.6 4.4 GO:0061198 fungiform papilla formation(GO:0061198)
0.6 2.4 GO:0021557 optic cup structural organization(GO:0003409) oculomotor nerve development(GO:0021557) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.6 1.8 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.6 45.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.6 6.0 GO:0072718 response to cisplatin(GO:0072718)
0.6 4.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.6 1.7 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.6 2.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.6 2.9 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.5 1.6 GO:0007538 primary sex determination(GO:0007538)
0.5 3.2 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.5 1.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.5 1.5 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.5 5.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.5 2.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.4 14.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 3.0 GO:0032218 riboflavin transport(GO:0032218)
0.4 2.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.4 2.1 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.4 6.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.4 1.6 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.4 6.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.4 38.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 2.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4 2.3 GO:0003164 His-Purkinje system development(GO:0003164)
0.4 1.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 2.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3 1.4 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.3 0.7 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.3 8.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.3 0.7 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.3 1.0 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.3 2.9 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 23.6 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3 1.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.3 5.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.3 2.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 1.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 2.7 GO:0070836 caveola assembly(GO:0070836)
0.3 0.8 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 2.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 2.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 3.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 3.1 GO:0042407 cristae formation(GO:0042407)
0.2 3.4 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.2 1.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.2 1.1 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2 5.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 0.6 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.2 4.9 GO:0016180 snRNA processing(GO:0016180)
0.2 0.6 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.2 2.1 GO:0032532 regulation of microvillus length(GO:0032532)
0.2 0.8 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 1.6 GO:0015886 heme transport(GO:0015886)
0.2 6.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.2 6.3 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.2 2.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 4.0 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.2 3.6 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.2 3.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 1.9 GO:0032808 lacrimal gland development(GO:0032808)
0.2 6.2 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.2 0.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 1.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 0.5 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.7 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) negative regulation of activation of membrane attack complex(GO:0001971)
0.1 1.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.8 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.6 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.1 0.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 2.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.5 GO:1903899 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 1.6 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 1.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.5 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.5 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 1.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 4.0 GO:0006266 DNA ligation(GO:0006266) telomere maintenance via semi-conservative replication(GO:0032201)
0.1 2.7 GO:0006853 carnitine shuttle(GO:0006853)
0.1 5.3 GO:0006308 DNA catabolic process(GO:0006308)
0.1 1.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 6.4 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 2.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.6 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.1 1.6 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 3.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 16.1 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 1.9 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 0.6 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.9 GO:0060613 fat pad development(GO:0060613)
0.1 2.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 6.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.1 17.0 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.1 1.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 10.0 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1 14.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 1.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 3.2 GO:0030252 growth hormone secretion(GO:0030252)
0.1 2.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 1.2 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 0.7 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 1.7 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.7 GO:0032262 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
0.1 0.9 GO:0030238 male sex determination(GO:0030238)
0.1 1.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 4.1 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.1 1.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 1.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 3.0 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.9 GO:0005984 disaccharide metabolic process(GO:0005984)
0.1 0.3 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 3.1 GO:0035904 aorta development(GO:0035904)
0.1 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 4.7 GO:0042100 B cell proliferation(GO:0042100)
0.1 0.7 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 1.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 2.7 GO:0018208 protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208)
0.1 3.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 1.5 GO:0045730 respiratory burst(GO:0045730)
0.1 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 2.9 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 2.7 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.3 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) negative regulation of cellular senescence(GO:2000773)
0.0 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 2.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 4.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 1.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 4.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 3.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:1904398 regulation of synaptic growth at neuromuscular junction(GO:0008582) positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.2 GO:0014010 Schwann cell proliferation(GO:0014010)
0.0 2.5 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.4 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.9 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 1.2 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 2.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 4.6 GO:0006909 phagocytosis(GO:0006909)
0.0 1.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.7 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.7 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 1.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.2 GO:0048678 response to axon injury(GO:0048678)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.0 GO:0061184 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184)
0.0 2.8 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.3 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.6 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 1.0 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.4 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 2.4 GO:0051170 nuclear import(GO:0051170)
0.0 0.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.0 GO:0042095 interferon-gamma biosynthetic process(GO:0042095) regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.6 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
1.6 6.2 GO:0070435 Shc-EGFR complex(GO:0070435)
1.2 3.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.0 3.1 GO:0043260 laminin-11 complex(GO:0043260)
0.9 2.8 GO:0034515 proteasome storage granule(GO:0034515)
0.8 41.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.8 4.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.8 3.9 GO:0001652 dense fibrillar component(GO:0001651) granular component(GO:0001652)
0.7 6.5 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.6 12.1 GO:0005861 troponin complex(GO:0005861)
0.6 2.8 GO:0031523 Myb complex(GO:0031523)
0.5 3.0 GO:0061617 MICOS complex(GO:0061617)
0.5 2.9 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.5 7.8 GO:0034709 methylosome(GO:0034709)
0.4 4.9 GO:0032039 integrator complex(GO:0032039)
0.4 2.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.4 1.9 GO:0019814 immunoglobulin complex(GO:0019814)
0.3 4.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 1.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.3 4.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.3 2.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.3 11.5 GO:0032420 stereocilium(GO:0032420)
0.2 9.8 GO:0005859 muscle myosin complex(GO:0005859)
0.2 2.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 1.4 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 3.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 4.4 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.6 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 3.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 5.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 1.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 6.0 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.2 1.5 GO:0032010 phagolysosome(GO:0032010)
0.2 5.5 GO:0000421 autophagosome membrane(GO:0000421)
0.2 4.0 GO:0042599 lamellar body(GO:0042599)
0.2 11.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 15.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 9.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 20.1 GO:0016605 PML body(GO:0016605)
0.1 1.7 GO:0001741 XY body(GO:0001741)
0.1 2.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.4 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 15.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.6 GO:0042555 MCM complex(GO:0042555)
0.1 7.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.1 GO:0016342 catenin complex(GO:0016342)
0.1 5.3 GO:0016459 myosin complex(GO:0016459)
0.1 7.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.9 GO:0061574 ASAP complex(GO:0061574)
0.1 2.0 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.1 11.8 GO:0072562 blood microparticle(GO:0072562)
0.1 8.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 6.3 GO:0000502 proteasome complex(GO:0000502)
0.1 4.2 GO:0005771 multivesicular body(GO:0005771)
0.1 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.4 GO:0060091 kinocilium(GO:0060091)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 6.4 GO:0005604 basement membrane(GO:0005604)
0.1 9.2 GO:0032993 protein-DNA complex(GO:0032993)
0.1 3.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 5.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 2.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.4 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 2.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 7.6 GO:0034774 secretory granule lumen(GO:0034774)
0.0 3.7 GO:0005901 caveola(GO:0005901)
0.0 2.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 3.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.5 GO:0045178 basal part of cell(GO:0045178)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 5.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0033093 intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310) Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 5.6 GO:0031966 mitochondrial membrane(GO:0031966)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
1.8 5.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.8 10.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.7 5.1 GO:0005046 KDEL sequence binding(GO:0005046)
1.7 5.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.3 7.8 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
1.1 3.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.0 4.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.0 19.6 GO:0050786 RAGE receptor binding(GO:0050786)
1.0 3.0 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
1.0 5.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.9 7.3 GO:0004111 creatine kinase activity(GO:0004111)
0.9 6.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.9 12.1 GO:0031014 troponin T binding(GO:0031014)
0.8 3.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.8 4.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.8 22.9 GO:0008301 DNA binding, bending(GO:0008301)
0.8 6.4 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.8 3.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.8 2.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.8 45.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.8 3.8 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.7 5.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.7 2.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.7 12.0 GO:0035497 cAMP response element binding(GO:0035497)
0.7 6.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.6 2.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6 1.8 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.6 2.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.6 2.8 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.5 9.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5 2.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.5 5.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 3.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.4 3.0 GO:0032217 riboflavin transporter activity(GO:0032217)
0.4 2.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.4 2.9 GO:0001849 complement component C1q binding(GO:0001849)
0.4 1.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4 1.6 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.4 2.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.4 2.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.4 3.6 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.3 2.4 GO:0019863 IgE binding(GO:0019863)
0.3 5.7 GO:0019864 IgG binding(GO:0019864)
0.3 2.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 0.9 GO:0032427 GBD domain binding(GO:0032427)
0.3 2.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 4.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 3.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 0.8 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 1.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.3 3.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 1.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.2 8.6 GO:0005123 death receptor binding(GO:0005123)
0.2 1.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 1.0 GO:0035939 microsatellite binding(GO:0035939)
0.2 13.8 GO:0016504 peptidase activator activity(GO:0016504)
0.2 1.0 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.2 5.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 0.7 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 3.5 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.2 1.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 1.6 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 4.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 6.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.9 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.2 3.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 3.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 1.6 GO:0015232 heme transporter activity(GO:0015232)
0.2 3.2 GO:0043295 glutathione binding(GO:0043295)
0.2 6.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.6 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 36.1 GO:0003823 antigen binding(GO:0003823)
0.2 1.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 2.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 2.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 3.5 GO:0005522 profilin binding(GO:0005522)
0.2 1.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 3.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 3.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 2.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 3.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 5.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 5.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 4.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.5 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.4 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 2.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 12.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 6.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 2.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 2.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 3.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.9 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 2.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.3 GO:0016805 dipeptidase activity(GO:0016805)
0.1 3.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 9.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 3.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 2.8 GO:0050699 WW domain binding(GO:0050699)
0.1 6.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 2.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 2.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 2.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 1.0 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 4.2 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.1 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 4.2 GO:0019003 GDP binding(GO:0019003)
0.0 1.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 6.6 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391)
0.0 3.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 3.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 4.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 2.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 1.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.9 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 1.2 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 23.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.3 3.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.3 15.9 PID IL3 PATHWAY IL3-mediated signaling events
0.3 9.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 3.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 10.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 8.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 3.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 14.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 3.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 7.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 4.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.5 PID IFNG PATHWAY IFN-gamma pathway
0.1 3.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 2.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.2 PID ARF 3PATHWAY Arf1 pathway
0.1 1.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 18.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.1 PID RHOA PATHWAY RhoA signaling pathway
0.1 18.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 10.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.1 PID ATR PATHWAY ATR signaling pathway
0.1 2.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 4.2 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 7.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 26.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 26.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 14.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 3.9 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.3 6.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 4.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 5.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.3 1.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 7.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 3.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 6.2 REACTOME KINESINS Genes involved in Kinesins
0.2 2.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 8.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 0.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 4.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 2.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 4.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 5.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 5.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 9.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 3.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 2.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 6.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.9 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 9.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.4 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 4.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 4.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 3.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 4.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 4.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 1.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions