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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for EGR3_EGR2
Z-value: 0.81
Motif logo
Transcription factors associated with EGR3_EGR2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
EGR3
|
ENSG00000179388.9 | EGR3 |
|
EGR2
|
ENSG00000122877.17 | EGR2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EGR3 | hg38_v1_chr8_-_22693469_22693487 | 0.10 | 1.3e-01 | Click! |
| EGR2 | hg38_v1_chr10_-_62816309_62816320, hg38_v1_chr10_-_62816341_62816388 | -0.05 | 4.6e-01 | Click! |
Activity profile of EGR3_EGR2 motif
Sorted Z-values of EGR3_EGR2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of EGR3_EGR2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 9.4 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 2.5 | 7.6 | GO:1990922 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 2.3 | 13.8 | GO:0051621 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470) |
| 2.2 | 6.7 | GO:0098582 | innate vocalization behavior(GO:0098582) |
| 1.8 | 5.3 | GO:0070429 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) |
| 1.7 | 8.5 | GO:1904674 | positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035) |
| 1.6 | 4.9 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 1.4 | 8.1 | GO:1900369 | regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) |
| 1.3 | 5.2 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 1.2 | 7.0 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 1.1 | 4.6 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 1.1 | 6.8 | GO:0032377 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 1.0 | 5.1 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 1.0 | 8.0 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 1.0 | 2.9 | GO:0048319 | axial mesoderm morphogenesis(GO:0048319) |
| 1.0 | 7.6 | GO:0003138 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 0.9 | 4.6 | GO:2000814 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 0.9 | 6.4 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.9 | 3.6 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.9 | 2.6 | GO:0036446 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
| 0.8 | 2.5 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.8 | 3.4 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.8 | 2.4 | GO:0008355 | olfactory learning(GO:0008355) |
| 0.8 | 3.9 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.8 | 3.0 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.7 | 3.0 | GO:0072237 | metanephric proximal tubule development(GO:0072237) |
| 0.7 | 2.8 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 0.7 | 2.7 | GO:1904800 | negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173) |
| 0.7 | 4.0 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.6 | 3.2 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 0.6 | 10.9 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
| 0.6 | 5.8 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
| 0.6 | 2.6 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.6 | 1.8 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 0.6 | 3.0 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 0.6 | 2.4 | GO:1903182 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 0.6 | 4.7 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.6 | 6.3 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.6 | 2.3 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 0.6 | 2.9 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.5 | 1.6 | GO:0001757 | somite specification(GO:0001757) |
| 0.5 | 1.1 | GO:0048807 | female genitalia morphogenesis(GO:0048807) |
| 0.5 | 1.6 | GO:0014873 | response to muscle activity involved in regulation of muscle adaptation(GO:0014873) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
| 0.5 | 6.2 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.5 | 1.0 | GO:2000969 | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.5 | 1.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.5 | 2.5 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 0.5 | 2.0 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 0.5 | 1.9 | GO:0000432 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) |
| 0.5 | 2.4 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.5 | 1.4 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
| 0.5 | 9.5 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 0.5 | 0.9 | GO:0035947 | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) |
| 0.5 | 1.4 | GO:0061011 | hepatic duct development(GO:0061011) |
| 0.5 | 0.9 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) |
| 0.5 | 1.4 | GO:0021530 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.4 | 2.7 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.4 | 1.8 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 0.4 | 1.3 | GO:0090187 | positive regulation of pancreatic juice secretion(GO:0090187) |
| 0.4 | 5.2 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
| 0.4 | 1.7 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.4 | 4.2 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.4 | 3.3 | GO:0044800 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
| 0.4 | 4.1 | GO:0046959 | habituation(GO:0046959) |
| 0.4 | 3.6 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.4 | 2.8 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 0.4 | 6.4 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.4 | 4.0 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.4 | 7.4 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
| 0.4 | 1.5 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.4 | 1.2 | GO:2000174 | regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 0.4 | 6.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.4 | 1.1 | GO:0030221 | basophil differentiation(GO:0030221) positive regulation of chromatin assembly or disassembly(GO:0045799) astrocyte fate commitment(GO:0060018) |
| 0.4 | 1.8 | GO:0090118 | receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) |
| 0.4 | 1.1 | GO:1903233 | regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) |
| 0.4 | 1.1 | GO:1902269 | positive regulation of polyamine transmembrane transport(GO:1902269) |
| 0.4 | 4.3 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.4 | 0.7 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) |
| 0.3 | 3.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.3 | 1.0 | GO:1902462 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 0.3 | 1.3 | GO:1903116 | positive regulation of actin filament-based movement(GO:1903116) positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170) |
| 0.3 | 1.3 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
| 0.3 | 1.9 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 0.3 | 2.9 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.3 | 2.9 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.3 | 4.1 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.3 | 1.6 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 0.3 | 0.9 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.3 | 3.4 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.3 | 1.8 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.3 | 7.6 | GO:1900273 | positive regulation of long-term synaptic potentiation(GO:1900273) |
| 0.3 | 0.9 | GO:0021586 | pons maturation(GO:0021586) |
| 0.3 | 1.2 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.3 | 0.9 | GO:2000417 | negative regulation of eosinophil migration(GO:2000417) |
| 0.3 | 1.2 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.3 | 0.9 | GO:0003064 | regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303) |
| 0.3 | 1.1 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.3 | 2.0 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.3 | 0.8 | GO:0070844 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.3 | 1.1 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.3 | 1.6 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 0.3 | 0.8 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.3 | 1.6 | GO:0019255 | UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255) |
| 0.3 | 12.3 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.3 | 4.1 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.2 | 0.7 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.2 | 2.5 | GO:2000138 | positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138) |
| 0.2 | 0.7 | GO:1901896 | positive regulation of calcium-transporting ATPase activity(GO:1901896) |
| 0.2 | 0.7 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 0.2 | 1.4 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.2 | 1.2 | GO:0030309 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.2 | 0.7 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 0.2 | 0.7 | GO:2000697 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697) |
| 0.2 | 1.1 | GO:1905232 | cellular response to L-glutamate(GO:1905232) |
| 0.2 | 2.7 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.2 | 0.4 | GO:0003342 | proepicardium development(GO:0003342) septum transversum development(GO:0003343) |
| 0.2 | 5.1 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.2 | 1.8 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.2 | 0.6 | GO:0045645 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 0.2 | 3.0 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.2 | 0.9 | GO:0032904 | viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472) |
| 0.2 | 2.7 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.2 | 1.9 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.2 | 1.0 | GO:2000705 | dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705) |
| 0.2 | 3.0 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.2 | 0.6 | GO:0071072 | negative regulation of phospholipid biosynthetic process(GO:0071072) |
| 0.2 | 0.4 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.2 | 0.6 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 0.2 | 2.1 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.2 | 1.2 | GO:0014057 | positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) |
| 0.2 | 1.6 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.2 | 0.8 | GO:0042091 | interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) |
| 0.2 | 0.6 | GO:1903719 | regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) |
| 0.2 | 0.4 | GO:2000077 | negative regulation of type B pancreatic cell development(GO:2000077) |
| 0.2 | 2.9 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.2 | 3.0 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.2 | 16.4 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.2 | 5.6 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.2 | 2.2 | GO:0032364 | oxygen homeostasis(GO:0032364) |
| 0.2 | 2.6 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.2 | 1.3 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.2 | 1.8 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.2 | 1.4 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.2 | 0.7 | GO:0060335 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.2 | 0.7 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.2 | 1.8 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.2 | 0.5 | GO:0036363 | transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389) |
| 0.2 | 0.9 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.2 | 0.2 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.2 | 0.8 | GO:1902047 | polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) |
| 0.2 | 0.7 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.2 | 0.8 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.2 | 3.0 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.2 | 0.5 | GO:0045212 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.2 | 1.4 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 0.1 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 0.1 | 1.0 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.1 | 2.5 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.1 | 0.6 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 0.1 | 1.4 | GO:0098907 | regulation of SA node cell action potential(GO:0098907) |
| 0.1 | 2.7 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.1 | 1.0 | GO:1902961 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 0.1 | 0.8 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.1 | 1.1 | GO:0032530 | regulation of microvillus organization(GO:0032530) regulation of microvillus length(GO:0032532) |
| 0.1 | 0.5 | GO:2000327 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.1 | 4.4 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.1 | 2.0 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.9 | GO:0071321 | cellular response to cGMP(GO:0071321) |
| 0.1 | 3.0 | GO:0014887 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.1 | 2.6 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.1 | 2.2 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.8 | GO:0032100 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 0.1 | 0.7 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.1 | 0.4 | GO:0060327 | cytoplasmic actin-based contraction involved in cell motility(GO:0060327) endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650) |
| 0.1 | 1.2 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.1 | 0.4 | GO:0052026 | modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
| 0.1 | 0.6 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.1 | 0.3 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 0.1 | 0.8 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.1 | 1.2 | GO:0021769 | orbitofrontal cortex development(GO:0021769) |
| 0.1 | 1.2 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.1 | 3.0 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 1.1 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 0.7 | GO:1902514 | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) |
| 0.1 | 0.9 | GO:0061577 | calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) |
| 0.1 | 0.8 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.1 | 0.7 | GO:0030421 | defecation(GO:0030421) |
| 0.1 | 1.1 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.1 | 1.3 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.1 | 0.3 | GO:0070105 | regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 0.1 | 0.4 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
| 0.1 | 0.6 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.1 | 4.8 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.1 | 6.9 | GO:0035722 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 0.1 | 0.3 | GO:0060382 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
| 0.1 | 3.5 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.1 | 0.3 | GO:0022007 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.1 | 1.6 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 2.1 | GO:0036152 | phosphatidylcholine acyl-chain remodeling(GO:0036151) phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 0.8 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 0.8 | GO:0045199 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.1 | 0.7 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.1 | 1.6 | GO:0097623 | potassium ion export across plasma membrane(GO:0097623) |
| 0.1 | 2.9 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.1 | 0.5 | GO:0042428 | serotonin metabolic process(GO:0042428) |
| 0.1 | 6.9 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 0.3 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 0.1 | 3.2 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 1.4 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 0.1 | 0.4 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.1 | 2.0 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.1 | 0.4 | GO:0015692 | lead ion transport(GO:0015692) |
| 0.1 | 0.3 | GO:0010956 | negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) |
| 0.1 | 1.1 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.1 | 0.5 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.1 | 1.7 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.1 | 0.8 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 6.1 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.1 | 0.2 | GO:0038162 | erythropoietin-mediated signaling pathway(GO:0038162) |
| 0.1 | 1.4 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 4.2 | GO:0030834 | regulation of actin filament depolymerization(GO:0030834) |
| 0.1 | 2.7 | GO:0010524 | positive regulation of calcium ion transport into cytosol(GO:0010524) |
| 0.1 | 2.9 | GO:0090022 | regulation of neutrophil chemotaxis(GO:0090022) |
| 0.1 | 0.3 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 0.4 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.1 | 0.4 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 0.5 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.4 | GO:0061511 | centriole elongation(GO:0061511) |
| 0.1 | 0.7 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 0.1 | GO:2000566 | positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
| 0.1 | 0.6 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.1 | 0.3 | GO:0032848 | negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
| 0.1 | 0.4 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.1 | 1.0 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.1 | 0.3 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416) |
| 0.1 | 0.4 | GO:2001206 | positive regulation of osteoclast development(GO:2001206) |
| 0.1 | 0.4 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
| 0.1 | 1.2 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 2.0 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.1 | 0.9 | GO:0070977 | bone maturation(GO:0070977) |
| 0.1 | 0.2 | GO:0032072 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.1 | 0.6 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 0.1 | 0.2 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.1 | 0.6 | GO:0022038 | corpus callosum development(GO:0022038) |
| 0.1 | 1.7 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.1 | 1.0 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 0.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.1 | 1.7 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.5 | GO:0003360 | brainstem development(GO:0003360) ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.1 | 0.9 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.1 | 0.3 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 0.1 | 0.8 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.1 | 2.3 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.1 | 1.4 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.3 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
| 0.1 | 0.3 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.1 | 0.4 | GO:0007512 | adult heart development(GO:0007512) |
| 0.1 | 1.8 | GO:1990090 | cellular response to nerve growth factor stimulus(GO:1990090) |
| 0.1 | 1.4 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
| 0.1 | 0.6 | GO:0050932 | regulation of pigment cell differentiation(GO:0050932) |
| 0.0 | 0.1 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.0 | 0.4 | GO:0034128 | negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) |
| 0.0 | 1.6 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.3 | GO:0046549 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.0 | 0.1 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 0.0 | 0.3 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
| 0.0 | 0.4 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.0 | 0.3 | GO:0061051 | positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) |
| 0.0 | 0.3 | GO:0033133 | fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.0 | 0.1 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.0 | 1.5 | GO:0050881 | multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881) |
| 0.0 | 0.7 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 0.8 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.0 | 1.6 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 0.7 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.0 | 0.8 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.6 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.4 | GO:0031086 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.0 | 0.3 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.5 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.0 | 0.3 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 0.1 | GO:0070375 | ERK5 cascade(GO:0070375) |
| 0.0 | 0.8 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
| 0.0 | 1.5 | GO:0046626 | regulation of insulin receptor signaling pathway(GO:0046626) |
| 0.0 | 0.4 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.0 | 0.8 | GO:0045724 | positive regulation of cilium assembly(GO:0045724) |
| 0.0 | 0.1 | GO:0097112 | gamma-aminobutyric acid receptor clustering(GO:0097112) |
| 0.0 | 1.7 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 2.1 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.9 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.0 | 0.3 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.0 | 1.4 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 0.7 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.0 | 0.5 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
| 0.0 | 2.1 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.4 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 0.4 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.6 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.0 | 0.9 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.0 | 0.1 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.0 | 0.2 | GO:0034776 | response to histamine(GO:0034776) cellular response to histamine(GO:0071420) |
| 0.0 | 0.4 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.3 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.0 | 0.2 | GO:0030812 | negative regulation of nucleotide catabolic process(GO:0030812) |
| 0.0 | 0.3 | GO:0070445 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
| 0.0 | 0.1 | GO:0006311 | meiotic gene conversion(GO:0006311) |
| 0.0 | 1.1 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.0 | 0.1 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 0.0 | 0.2 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.0 | 0.2 | GO:1904098 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.0 | 0.4 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.0 | 0.6 | GO:0006743 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.2 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.0 | 0.5 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 0.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.3 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.0 | 0.8 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.0 | 0.1 | GO:0030822 | regulation of cyclic nucleotide catabolic process(GO:0030805) positive regulation of cyclic nucleotide catabolic process(GO:0030807) regulation of cAMP catabolic process(GO:0030820) positive regulation of cAMP catabolic process(GO:0030822) regulation of purine nucleotide catabolic process(GO:0033121) positive regulation of purine nucleotide catabolic process(GO:0033123) |
| 0.0 | 9.2 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.0 | 1.4 | GO:0042267 | natural killer cell mediated cytotoxicity(GO:0042267) |
| 0.0 | 0.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.5 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.0 | 0.1 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.0 | 1.2 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.7 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.0 | 0.1 | GO:0051933 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
| 0.0 | 0.5 | GO:0010715 | regulation of extracellular matrix disassembly(GO:0010715) |
| 0.0 | 4.9 | GO:0006469 | negative regulation of protein kinase activity(GO:0006469) |
| 0.0 | 1.3 | GO:0050806 | positive regulation of synaptic transmission(GO:0050806) |
| 0.0 | 0.1 | GO:0043987 | histone H3-S10 phosphorylation(GO:0043987) |
| 0.0 | 0.7 | GO:0035249 | synaptic transmission, glutamatergic(GO:0035249) |
| 0.0 | 0.3 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 0.0 | 0.7 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 0.1 | GO:0048755 | branching morphogenesis of a nerve(GO:0048755) |
| 0.0 | 0.3 | GO:0030050 | vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515) |
| 0.0 | 0.5 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.6 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.2 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.0 | 0.2 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.0 | 0.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.5 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.0 | 0.2 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.0 | 0.1 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.8 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.0 | 0.4 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.0 | 0.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.0 | 0.6 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.0 | 0.2 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.0 | 2.7 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 0.3 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 0.0 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.0 | 0.2 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.4 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 0.1 | GO:0031629 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.0 | 0.5 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.7 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 0.6 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.0 | 0.7 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.0 | 0.0 | GO:1900451 | positive regulation of glutamate receptor signaling pathway(GO:1900451) |
| 0.0 | 0.1 | GO:0006290 | pyrimidine dimer repair(GO:0006290) |
| 0.0 | 1.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.2 | GO:0030837 | negative regulation of actin filament polymerization(GO:0030837) |
| 0.0 | 1.6 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.0 | 0.1 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.1 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 0.0 | GO:0060013 | righting reflex(GO:0060013) |
| 0.0 | 0.1 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 0.0 | 0.0 | GO:0060300 | regulation of cytokine activity(GO:0060300) |
| 0.0 | 0.1 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 0.0 | 0.3 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.0 | 0.3 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.2 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 9.4 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 1.6 | 14.2 | GO:0044327 | dendritic spine head(GO:0044327) |
| 1.4 | 5.6 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 1.2 | 8.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 1.1 | 9.0 | GO:0060199 | clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) |
| 0.9 | 4.4 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.7 | 3.0 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.7 | 5.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.7 | 6.9 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.6 | 2.4 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 0.5 | 2.0 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.5 | 4.6 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.4 | 2.2 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.4 | 16.3 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.4 | 4.1 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.3 | 6.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.3 | 2.5 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.3 | 4.9 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.3 | 1.5 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 0.3 | 4.5 | GO:0005883 | neurofilament(GO:0005883) |
| 0.3 | 5.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.3 | 1.5 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.2 | 0.7 | GO:0000805 | X chromosome(GO:0000805) |
| 0.2 | 1.4 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.2 | 1.1 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.2 | 2.3 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.2 | 3.8 | GO:0008091 | spectrin(GO:0008091) |
| 0.2 | 11.3 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.2 | 1.9 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.2 | 1.7 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.2 | 2.3 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.2 | 5.0 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 0.4 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.2 | 10.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.2 | 9.4 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.2 | 0.8 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.2 | 0.9 | GO:0070938 | contractile ring(GO:0070938) |
| 0.2 | 0.9 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.2 | 0.5 | GO:1990917 | sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917) |
| 0.2 | 3.0 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.2 | 0.9 | GO:0089701 | U2AF(GO:0089701) |
| 0.2 | 3.8 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.2 | 3.6 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.2 | 10.9 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.2 | 1.7 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 1.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 2.7 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 2.2 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.1 | 0.9 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.1 | 1.9 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 2.9 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 2.0 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 1.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.8 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.1 | 0.3 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.1 | 2.5 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.1 | 0.5 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.1 | 2.6 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 0.7 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 1.9 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 0.7 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 19.6 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 1.2 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.1 | 0.6 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 4.0 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 1.2 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.1 | 1.7 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 4.1 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.1 | 5.6 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.1 | 2.8 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 1.8 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 1.2 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 0.7 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 0.4 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.1 | 0.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 3.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 2.0 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 0.4 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 2.0 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 1.6 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.1 | 6.4 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 1.6 | GO:0044453 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.1 | 1.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 0.4 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 0.7 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.1 | 2.5 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 0.5 | GO:0044294 | dendrite terminus(GO:0044292) dendritic growth cone(GO:0044294) |
| 0.1 | 0.3 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 0.6 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.1 | 3.8 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 0.2 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 0.7 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 0.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 0.4 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 0.3 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 1.8 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.1 | 0.4 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.1 | 8.5 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 0.4 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 0.5 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 1.9 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.1 | 1.2 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 0.4 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.3 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.0 | 4.4 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.7 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.0 | 1.0 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 0.2 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.0 | 0.5 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.0 | 1.6 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
| 0.0 | 0.5 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.0 | 11.1 | GO:0099572 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 5.2 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 2.2 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.7 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.0 | 3.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.0 | 1.5 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
| 0.0 | 1.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 6.6 | GO:0098794 | postsynapse(GO:0098794) |
| 0.0 | 0.2 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.0 | 0.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 0.9 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 3.8 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 2.0 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 1.1 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.5 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.7 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 6.0 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 0.2 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 1.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 1.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 1.0 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.3 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.2 | GO:0001741 | XY body(GO:0001741) |
| 0.0 | 0.4 | GO:0005684 | U2-type spliceosomal complex(GO:0005684) |
| 0.0 | 1.2 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 15.4 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 0.1 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 0.4 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 1.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.4 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 0.4 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 2.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.1 | GO:0032302 | MutSalpha complex(GO:0032301) MutSbeta complex(GO:0032302) |
| 0.0 | 0.2 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 0.1 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 3.1 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 0.2 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.0 | 0.3 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.6 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 1.1 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 0.6 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.8 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.0 | 0.2 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 0.0 | 0.2 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.7 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.7 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 13.8 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 1.4 | 5.6 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 1.1 | 14.9 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 1.0 | 9.4 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 1.0 | 8.1 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 1.0 | 3.0 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 1.0 | 4.9 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.9 | 9.3 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.8 | 5.1 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 0.8 | 8.7 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.8 | 3.2 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.8 | 3.0 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.7 | 15.1 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.7 | 5.5 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.7 | 4.0 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.7 | 15.7 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.6 | 1.9 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.6 | 2.4 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 0.6 | 2.4 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 0.6 | 5.1 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.6 | 3.4 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.6 | 2.8 | GO:0052827 | inositol pentakisphosphate phosphatase activity(GO:0052827) |
| 0.5 | 7.5 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.5 | 1.5 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.5 | 2.4 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.5 | 1.8 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.4 | 1.8 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 0.4 | 2.2 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.4 | 1.7 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.4 | 1.7 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 0.4 | 3.4 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.4 | 4.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.4 | 13.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.4 | 1.6 | GO:0051748 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 0.4 | 5.1 | GO:0030284 | estrogen receptor activity(GO:0030284) |
| 0.4 | 3.6 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.4 | 0.4 | GO:0086062 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 0.4 | 2.5 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.3 | 1.0 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.3 | 1.0 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 0.3 | 1.9 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.3 | 2.9 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.3 | 1.2 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.3 | 0.9 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.3 | 0.9 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.3 | 3.2 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.3 | 3.4 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.3 | 5.5 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.3 | 1.1 | GO:0004513 | neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291) |
| 0.3 | 2.1 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.3 | 2.4 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.3 | 0.8 | GO:0004796 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 0.3 | 1.5 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.2 | 4.7 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.2 | 4.9 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.2 | 0.7 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.2 | 4.9 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.2 | 1.4 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 1.2 | GO:0008532 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) |
| 0.2 | 0.7 | GO:0098973 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 0.2 | 4.7 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.2 | 2.1 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.2 | 3.2 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.2 | 6.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 1.5 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.2 | 1.3 | GO:0034191 | apolipoprotein A-I receptor binding(GO:0034191) |
| 0.2 | 10.0 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.2 | 2.8 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.2 | 0.6 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 0.2 | 1.9 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.2 | 1.3 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.2 | 6.9 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.2 | 1.7 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.2 | 1.4 | GO:0030250 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.2 | 4.1 | GO:0005522 | profilin binding(GO:0005522) |
| 0.2 | 2.4 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.2 | 1.6 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.2 | 1.2 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.2 | 1.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.2 | 0.7 | GO:0070404 | NADH binding(GO:0070404) |
| 0.2 | 2.5 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.2 | 0.9 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.2 | 0.5 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.2 | 0.5 | GO:0002135 | CTP binding(GO:0002135) |
| 0.2 | 0.5 | GO:0032093 | SAM domain binding(GO:0032093) |
| 0.2 | 2.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.2 | 2.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.2 | 2.9 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.2 | 0.8 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.2 | 5.7 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.2 | 0.5 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.2 | 0.7 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.2 | 0.8 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.2 | 2.9 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.2 | 1.1 | GO:0042979 | ornithine decarboxylase regulator activity(GO:0042979) |
| 0.2 | 2.5 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.2 | 0.6 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.2 | 2.1 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 1.6 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.1 | 0.1 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) |
| 0.1 | 0.7 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.1 | 1.5 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.1 | 0.6 | GO:0004356 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.1 | 4.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 1.6 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.1 | 0.5 | GO:0010857 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857) |
| 0.1 | 1.2 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.1 | 1.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.1 | 1.9 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.1 | 0.5 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 0.1 | 0.4 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.1 | 0.5 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
| 0.1 | 0.4 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.1 | 0.5 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.1 | 0.5 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.1 | 1.0 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 1.0 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.1 | 0.7 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.1 | 0.7 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.1 | 2.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.5 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.1 | 0.3 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.1 | 1.0 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.1 | 6.9 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 0.7 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.1 | 0.7 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.1 | 0.4 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.1 | 0.7 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.3 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
| 0.1 | 1.0 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.1 | 0.6 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 0.5 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 2.3 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 0.6 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 1.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 0.8 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.1 | 0.8 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.1 | 1.1 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.3 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.1 | 0.7 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 2.8 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 1.1 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 0.4 | GO:0015639 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.1 | 1.5 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 0.8 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 0.1 | 3.7 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 0.8 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.1 | 0.4 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.1 | 1.1 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 1.6 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 0.9 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.1 | 0.8 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.1 | 0.9 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 0.4 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.1 | 1.3 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.1 | 1.1 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.1 | 1.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 0.4 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.1 | 3.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 0.6 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.1 | 6.6 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.1 | 0.4 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.1 | 2.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 1.1 | GO:0019841 | retinal binding(GO:0016918) retinol binding(GO:0019841) |
| 0.1 | 0.3 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.1 | 7.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 0.2 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 0.5 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.1 | 0.2 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 0.1 | 1.6 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.1 | 1.0 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.1 | 1.6 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 0.5 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.1 | 0.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.4 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 1.7 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 1.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.8 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.8 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.1 | 1.2 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 0.5 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.1 | 0.3 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.1 | 0.4 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 2.5 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.1 | 0.8 | GO:0042577 | phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577) |
| 0.1 | 0.8 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 0.4 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 9.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 0.4 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.1 | 1.2 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 3.9 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.1 | 0.9 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.1 | 0.2 | GO:0042282 | hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282) |
| 0.1 | 3.4 | GO:1902936 | phosphatidylinositol bisphosphate binding(GO:1902936) |
| 0.1 | 0.8 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 2.8 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.1 | 4.0 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 1.1 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 0.3 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.0 | 0.2 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.0 | 0.1 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 0.0 | 1.2 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.0 | 0.3 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.0 | 0.1 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.0 | 3.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 5.1 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.6 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 2.3 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 3.6 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.5 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 0.5 | GO:0016004 | phospholipase activator activity(GO:0016004) |
| 0.0 | 0.2 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.0 | 0.3 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 2.4 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.3 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.6 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 2.2 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.4 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 1.0 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.3 | GO:0015185 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 0.0 | 0.4 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
| 0.0 | 1.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.6 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 6.5 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 0.4 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.2 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.6 | GO:0035250 | UDP-galactosyltransferase activity(GO:0035250) |
| 0.0 | 0.2 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.0 | 1.0 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.2 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.0 | 0.3 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.4 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.4 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.0 | 0.5 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 1.8 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 0.9 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 0.5 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.0 | 0.6 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.0 | 7.1 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.3 | GO:0036041 | long-chain fatty acid binding(GO:0036041) |
| 0.0 | 0.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.7 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 1.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.8 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.4 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 1.3 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.2 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.0 | 0.1 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.0 | 1.5 | GO:0016247 | channel regulator activity(GO:0016247) |
| 0.0 | 0.6 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.0 | 0.7 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.0 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.0 | 2.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.3 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.0 | 0.1 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.0 | 0.2 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 1.3 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.1 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.1 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 0.0 | 0.1 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.0 | 0.6 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.4 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 2.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.2 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 1.8 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.1 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.0 | GO:0005113 | patched binding(GO:0005113) |
| 0.0 | 0.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 12.0 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.5 | 25.0 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.3 | 18.3 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.3 | 3.3 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.3 | 13.1 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.2 | 2.7 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.2 | 4.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.2 | 3.1 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.2 | 8.4 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.2 | 6.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 2.9 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.2 | 8.1 | PID MYC PATHWAY | C-MYC pathway |
| 0.2 | 8.8 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.2 | 3.9 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.2 | 2.4 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.1 | 7.1 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 3.0 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.1 | 3.0 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.1 | 3.5 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 2.7 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 1.2 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.1 | 6.7 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 6.6 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.1 | 2.9 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.1 | 4.6 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.1 | 3.6 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.1 | 10.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 0.7 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 4.0 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 3.3 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.1 | 1.4 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 3.9 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 3.3 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 0.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 2.0 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 0.1 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 1.8 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 1.1 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.0 | 2.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 2.6 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 2.0 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 3.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.6 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.5 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.8 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 1.0 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.5 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.8 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.3 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.5 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 1.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.3 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.9 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 0.2 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 0.4 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.2 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 0.1 | ST GA12 PATHWAY | G alpha 12 Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 16.3 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.6 | 3.6 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.6 | 2.9 | REACTOME SIGNALING BY ERBB4 | Genes involved in Signaling by ERBB4 |
| 0.5 | 5.7 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.4 | 9.4 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.4 | 14.2 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.4 | 11.5 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.3 | 6.7 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.3 | 8.2 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.3 | 14.7 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.3 | 6.8 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.3 | 6.6 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.3 | 2.6 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.3 | 4.0 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.2 | 10.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.2 | 7.3 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.2 | 5.1 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.2 | 6.7 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.2 | 8.9 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.2 | 1.4 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.2 | 4.0 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.2 | 1.8 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.2 | 3.8 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.2 | 4.0 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 5.6 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.2 | 6.0 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.2 | 6.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.2 | 11.6 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.2 | 6.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 5.6 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.1 | 2.8 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.1 | 5.1 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.1 | 1.5 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.1 | 0.6 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 3.1 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 4.9 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.1 | 0.4 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.1 | 8.1 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 3.2 | REACTOME RNA POL I TRANSCRIPTION INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
| 0.1 | 1.0 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.1 | 1.8 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 1.6 | REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | Genes involved in Processive synthesis on the lagging strand |
| 0.1 | 2.0 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.1 | 9.7 | REACTOME REGULATION OF INSULIN SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.1 | 1.8 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 0.1 | 1.6 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 0.9 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 1.1 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 0.3 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.1 | 6.1 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 1.6 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 2.1 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 2.0 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 3.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 1.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 2.5 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 0.5 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 1.3 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 1.2 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.7 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.0 | 2.4 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 1.8 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.8 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.3 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 0.4 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 0.0 | 1.9 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.7 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.0 | 0.6 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 0.5 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.0 | 0.6 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.4 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.0 | 0.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.6 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 4.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.2 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 0.7 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.8 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.0 | 1.3 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.7 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.5 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 3.3 | REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | Genes involved in Transmission across Chemical Synapses |
| 0.0 | 2.0 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 0.4 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.6 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.7 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 1.7 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.0 | 0.4 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 0.5 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 1.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 3.4 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 1.2 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.7 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 0.3 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.0 | 0.1 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 0.3 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 0.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 0.6 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.6 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.5 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.2 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.1 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.0 | 0.3 | REACTOME SIGNALING BY FGFR | Genes involved in Signaling by FGFR |
| 0.0 | 1.2 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |