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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for ELK4_ETV5_ELK1_ELK3_ELF4
Z-value: 2.99
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Transcription factors associated with ELK4_ETV5_ELK1_ELK3_ELF4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ELK4
|
ENSG00000158711.14 | ELK4 |
|
ETV5
|
ENSG00000244405.8 | ETV5 |
|
ELK1
|
ENSG00000126767.18 | ELK1 |
|
ELK3
|
ENSG00000111145.8 | ELK3 |
|
ELF4
|
ENSG00000102034.17 | ELF4 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ELK4 | hg38_v1_chr1_-_205631962_205632030 | -0.49 | 2.0e-14 | Click! |
| ELK1 | hg38_v1_chrX_-_47650488_47650591 | -0.46 | 6.4e-13 | Click! |
| ELF4 | hg38_v1_chrX_-_130110679_130110722, hg38_v1_chrX_-_130110479_130110514 | 0.42 | 8.7e-11 | Click! |
| ELK3 | hg38_v1_chr12_+_96194501_96194545 | -0.42 | 9.1e-11 | Click! |
| ETV5 | hg38_v1_chr3_-_186109067_186109117 | 0.19 | 5.4e-03 | Click! |
Activity profile of ELK4_ETV5_ELK1_ELK3_ELF4 motif
Sorted Z-values of ELK4_ETV5_ELK1_ELK3_ELF4 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ELK4_ETV5_ELK1_ELK3_ELF4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 55.6 | 166.8 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
| 54.6 | 163.7 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 48.8 | 146.5 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
| 47.6 | 142.9 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 46.3 | 138.9 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 41.2 | 206.2 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 38.8 | 116.5 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 35.6 | 142.2 | GO:0000912 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 35.5 | 177.5 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 33.8 | 169.2 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 33.6 | 100.8 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 31.6 | 126.4 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 30.7 | 184.4 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 30.7 | 153.7 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 30.7 | 184.2 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 30.0 | 89.9 | GO:0070476 | RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 29.8 | 89.4 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 28.2 | 394.7 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 28.1 | 84.4 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) |
| 26.6 | 79.8 | GO:0002188 | translation reinitiation(GO:0002188) |
| 26.2 | 104.8 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 26.1 | 78.3 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 25.8 | 77.4 | GO:0051793 | medium-chain fatty acid catabolic process(GO:0051793) |
| 25.7 | 102.6 | GO:0006404 | RNA import into nucleus(GO:0006404) |
| 25.1 | 100.6 | GO:0007144 | female meiosis I(GO:0007144) |
| 24.8 | 24.8 | GO:0009838 | abscission(GO:0009838) |
| 24.7 | 24.7 | GO:0046070 | dGTP metabolic process(GO:0046070) |
| 24.5 | 73.6 | GO:1902568 | positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
| 24.3 | 72.8 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 23.4 | 164.0 | GO:0032218 | riboflavin transport(GO:0032218) |
| 23.2 | 69.6 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 23.2 | 139.2 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 22.3 | 89.1 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 20.9 | 62.7 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 20.1 | 100.4 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 20.0 | 200.5 | GO:0009146 | purine nucleoside triphosphate catabolic process(GO:0009146) |
| 19.7 | 59.1 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 19.7 | 59.0 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 19.5 | 39.0 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 19.1 | 133.9 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 19.1 | 76.4 | GO:2000434 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 19.1 | 114.6 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 18.7 | 56.1 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 18.6 | 55.9 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 18.6 | 186.0 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
| 18.4 | 73.8 | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) |
| 18.3 | 73.3 | GO:2000426 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 18.3 | 18.3 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 18.2 | 18.2 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
| 18.1 | 72.6 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 18.0 | 90.1 | GO:0016074 | snoRNA metabolic process(GO:0016074) snoRNA processing(GO:0043144) |
| 17.9 | 232.4 | GO:0043248 | proteasome assembly(GO:0043248) |
| 17.2 | 51.6 | GO:0097698 | telomere maintenance via base-excision repair(GO:0097698) |
| 17.2 | 86.1 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 17.0 | 50.9 | GO:0071283 | cellular response to iron(III) ion(GO:0071283) |
| 16.9 | 50.8 | GO:0015846 | polyamine transport(GO:0015846) |
| 16.5 | 99.0 | GO:1903679 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 16.5 | 659.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 16.5 | 181.2 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 16.4 | 49.1 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
| 16.0 | 112.3 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 15.9 | 47.8 | GO:1904732 | regulation of electron carrier activity(GO:1904732) |
| 15.9 | 31.8 | GO:0071033 | nuclear retention of pre-mRNA at the site of transcription(GO:0071033) |
| 15.7 | 62.9 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 15.5 | 46.4 | GO:1903722 | regulation of centriole elongation(GO:1903722) |
| 15.5 | 77.3 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 15.3 | 92.0 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 15.3 | 61.2 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 15.2 | 121.3 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 14.7 | 132.6 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 14.6 | 1361.5 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 14.4 | 202.1 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 14.2 | 70.9 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 14.0 | 70.2 | GO:0009204 | deoxyribonucleoside triphosphate catabolic process(GO:0009204) |
| 13.9 | 139.2 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 13.8 | 55.1 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 13.7 | 219.9 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 13.7 | 82.0 | GO:1904872 | regulation of telomerase RNA localization to Cajal body(GO:1904872) |
| 13.7 | 27.3 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 13.6 | 1111.8 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 13.4 | 53.8 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 13.4 | 187.8 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 13.3 | 66.5 | GO:0031125 | rRNA 3'-end processing(GO:0031125) |
| 13.3 | 53.0 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 13.2 | 79.4 | GO:0009211 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
| 13.1 | 971.8 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 13.1 | 39.4 | GO:0001189 | RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189) |
| 13.0 | 130.1 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) |
| 13.0 | 51.9 | GO:0046116 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 12.9 | 205.7 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 12.9 | 51.4 | GO:0051182 | coenzyme transport(GO:0051182) |
| 12.4 | 161.0 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 12.3 | 234.0 | GO:0075713 | establishment of integrated proviral latency(GO:0075713) |
| 12.3 | 24.6 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 12.3 | 49.1 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 12.3 | 184.3 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 12.3 | 49.0 | GO:0016334 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 11.8 | 94.7 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 11.8 | 177.4 | GO:0000338 | protein deneddylation(GO:0000338) |
| 11.8 | 35.3 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 11.8 | 35.3 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 11.7 | 35.2 | GO:1902524 | positive regulation of protein K48-linked ubiquitination(GO:1902524) |
| 11.6 | 510.1 | GO:0009452 | 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 11.5 | 11.5 | GO:0019878 | lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) |
| 11.5 | 34.4 | GO:1902822 | lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822) |
| 11.4 | 34.1 | GO:0070902 | mitochondrial tRNA pseudouridine synthesis(GO:0070902) |
| 11.3 | 33.9 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 11.3 | 101.6 | GO:0090151 | protein import into mitochondrial inner membrane(GO:0045039) establishment of protein localization to mitochondrial membrane(GO:0090151) |
| 11.3 | 33.8 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 11.3 | 67.5 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 11.1 | 22.2 | GO:0046984 | regulation of hemoglobin biosynthetic process(GO:0046984) |
| 11.0 | 43.9 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 10.8 | 161.4 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 10.7 | 42.6 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 10.5 | 73.8 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 10.5 | 157.4 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 10.2 | 71.7 | GO:1990592 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 10.2 | 193.7 | GO:0006144 | purine nucleobase metabolic process(GO:0006144) |
| 10.1 | 20.2 | GO:2000374 | regulation of oxygen metabolic process(GO:2000374) |
| 10.1 | 261.5 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 10.0 | 50.2 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 9.9 | 29.8 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 9.8 | 29.4 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 9.7 | 19.4 | GO:0098502 | DNA dephosphorylation(GO:0098502) |
| 9.7 | 174.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 9.6 | 67.0 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 9.5 | 38.1 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 9.4 | 113.2 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 9.4 | 75.1 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 9.2 | 101.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 9.2 | 109.9 | GO:0006983 | ER overload response(GO:0006983) |
| 9.2 | 54.9 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 9.1 | 36.5 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 9.1 | 45.6 | GO:0072396 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 9.0 | 17.9 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 9.0 | 26.9 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
| 8.9 | 35.6 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 8.8 | 17.7 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 8.7 | 43.7 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 8.7 | 52.4 | GO:0097052 | L-kynurenine metabolic process(GO:0097052) |
| 8.7 | 8.7 | GO:0090155 | negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) |
| 8.7 | 26.1 | GO:0042727 | flavin-containing compound biosynthetic process(GO:0042727) |
| 8.7 | 26.1 | GO:0042946 | glucoside transport(GO:0042946) |
| 8.6 | 85.8 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 8.5 | 25.6 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 8.5 | 51.1 | GO:0015680 | intracellular copper ion transport(GO:0015680) |
| 8.5 | 25.4 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 8.5 | 16.9 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 8.4 | 101.4 | GO:0042407 | cristae formation(GO:0042407) |
| 8.4 | 67.4 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 8.4 | 143.1 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 8.4 | 41.9 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 8.3 | 74.5 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 8.2 | 148.2 | GO:0060546 | negative regulation of necroptotic process(GO:0060546) |
| 8.2 | 24.6 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 8.2 | 32.7 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 8.1 | 48.4 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 8.0 | 96.6 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 8.0 | 48.3 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 8.0 | 64.0 | GO:0045176 | apical protein localization(GO:0045176) |
| 7.9 | 7.9 | GO:1903093 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 7.9 | 55.0 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 7.8 | 508.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 7.8 | 23.4 | GO:0035048 | splicing factor protein import into nucleus(GO:0035048) |
| 7.8 | 23.4 | GO:0070512 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
| 7.7 | 38.7 | GO:0016240 | autophagosome docking(GO:0016240) |
| 7.7 | 30.7 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 7.6 | 22.9 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 7.6 | 22.8 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 7.6 | 76.1 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 7.6 | 68.3 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 7.6 | 22.7 | GO:0048254 | snoRNA localization(GO:0048254) |
| 7.4 | 37.2 | GO:0045337 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 7.4 | 89.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 7.4 | 22.2 | GO:0034238 | macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) |
| 7.4 | 44.4 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 7.3 | 102.9 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 7.2 | 36.2 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 7.2 | 50.7 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 7.1 | 35.7 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 7.1 | 21.3 | GO:1901355 | response to rapamycin(GO:1901355) |
| 7.1 | 21.3 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 7.0 | 28.1 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 7.0 | 35.1 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 7.0 | 328.7 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
| 6.9 | 20.8 | GO:0007174 | epidermal growth factor catabolic process(GO:0007174) |
| 6.9 | 6.9 | GO:0098507 | polynucleotide 5' dephosphorylation(GO:0098507) |
| 6.9 | 6.9 | GO:0070197 | telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 6.9 | 20.6 | GO:0009177 | dUMP biosynthetic process(GO:0006226) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) |
| 6.8 | 54.3 | GO:0070200 | establishment of protein localization to telomere(GO:0070200) |
| 6.8 | 20.3 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 6.8 | 54.2 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 6.7 | 60.0 | GO:0006528 | asparagine metabolic process(GO:0006528) |
| 6.6 | 39.7 | GO:0006050 | mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051) |
| 6.6 | 13.2 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 6.6 | 26.4 | GO:0045950 | meiotic metaphase I plate congression(GO:0043060) negative regulation of mitotic recombination(GO:0045950) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 6.6 | 26.3 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 6.6 | 19.7 | GO:0018406 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 6.5 | 19.6 | GO:0036483 | neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382) |
| 6.5 | 52.0 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 6.5 | 6.5 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 6.4 | 25.7 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 6.4 | 83.6 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 6.4 | 32.0 | GO:0051792 | medium-chain fatty acid biosynthetic process(GO:0051792) |
| 6.4 | 12.8 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 6.4 | 12.8 | GO:0043335 | protein unfolding(GO:0043335) |
| 6.4 | 108.3 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 6.4 | 654.8 | GO:0045047 | protein targeting to ER(GO:0045047) |
| 6.3 | 18.9 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 6.2 | 24.8 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 6.2 | 55.6 | GO:0033750 | ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) |
| 6.2 | 30.9 | GO:1900368 | regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) |
| 6.2 | 24.7 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 6.2 | 61.6 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 6.2 | 18.5 | GO:2000687 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 6.1 | 30.7 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 6.1 | 18.3 | GO:0071072 | negative regulation of phospholipid biosynthetic process(GO:0071072) |
| 6.1 | 249.0 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 6.0 | 18.1 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 6.0 | 107.7 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 5.9 | 5.9 | GO:1904884 | establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 5.9 | 11.7 | GO:0019081 | viral translation(GO:0019081) IRES-dependent viral translational initiation(GO:0075522) |
| 5.8 | 35.1 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 5.8 | 34.9 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 5.8 | 23.3 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
| 5.8 | 11.6 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 5.7 | 22.8 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) asymmetric Golgi ribbon formation(GO:0090164) |
| 5.7 | 22.7 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 5.7 | 22.6 | GO:0046203 | spermidine catabolic process(GO:0046203) |
| 5.7 | 17.0 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 5.6 | 11.2 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 5.6 | 16.9 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 5.6 | 89.5 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 5.6 | 39.0 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 5.6 | 50.0 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 5.5 | 105.4 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 5.5 | 22.1 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 5.5 | 60.6 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 5.5 | 110.0 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
| 5.5 | 22.0 | GO:0018008 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) |
| 5.5 | 33.0 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 5.5 | 16.4 | GO:0002905 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 5.4 | 10.9 | GO:0002424 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) |
| 5.4 | 27.2 | GO:1902101 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
| 5.4 | 16.3 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 5.4 | 86.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 5.4 | 5.4 | GO:0001302 | replicative cell aging(GO:0001302) |
| 5.4 | 54.0 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 5.3 | 26.7 | GO:0042262 | DNA protection(GO:0042262) |
| 5.3 | 37.3 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 5.3 | 26.4 | GO:0002439 | chronic inflammatory response to antigenic stimulus(GO:0002439) |
| 5.3 | 37.0 | GO:1905216 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
| 5.3 | 52.7 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 5.2 | 36.3 | GO:0000012 | single strand break repair(GO:0000012) |
| 5.2 | 15.5 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 5.1 | 41.1 | GO:0002183 | cytoplasmic translational initiation(GO:0002183) |
| 5.1 | 15.3 | GO:0014810 | positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810) |
| 5.0 | 15.1 | GO:0036111 | very long-chain fatty-acyl-CoA metabolic process(GO:0036111) |
| 5.0 | 20.0 | GO:0050689 | negative regulation of defense response to virus by host(GO:0050689) |
| 5.0 | 350.0 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 5.0 | 54.8 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 5.0 | 24.9 | GO:0015677 | copper ion import(GO:0015677) |
| 4.9 | 19.7 | GO:0045917 | positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 4.9 | 34.1 | GO:1903895 | negative regulation of IRE1-mediated unfolded protein response(GO:1903895) |
| 4.8 | 24.1 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 4.8 | 19.2 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
| 4.8 | 14.3 | GO:0036233 | glycine import(GO:0036233) |
| 4.7 | 9.5 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
| 4.7 | 23.6 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 4.7 | 18.6 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 4.7 | 37.2 | GO:0051026 | chiasma assembly(GO:0051026) |
| 4.6 | 241.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 4.6 | 4.6 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 4.6 | 4.6 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 4.5 | 109.2 | GO:1904667 | negative regulation of ubiquitin protein ligase activity(GO:1904667) |
| 4.5 | 27.1 | GO:0046146 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 4.5 | 4.5 | GO:1903436 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 4.4 | 4.4 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 4.4 | 17.6 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 4.4 | 48.4 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 4.4 | 65.9 | GO:0010257 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 4.4 | 17.5 | GO:1901873 | regulation of post-translational protein modification(GO:1901873) |
| 4.4 | 69.9 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 4.4 | 21.8 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 4.3 | 17.4 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 4.3 | 17.4 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 4.3 | 4.3 | GO:0045715 | negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
| 4.3 | 17.3 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
| 4.3 | 8.6 | GO:0034214 | protein hexamerization(GO:0034214) |
| 4.3 | 21.6 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 4.3 | 8.6 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
| 4.3 | 34.3 | GO:1904798 | positive regulation of core promoter binding(GO:1904798) |
| 4.3 | 12.8 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 4.3 | 8.5 | GO:0033206 | meiotic cytokinesis(GO:0033206) |
| 4.3 | 38.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 4.3 | 12.8 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
| 4.2 | 21.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 4.2 | 97.5 | GO:0006119 | oxidative phosphorylation(GO:0006119) |
| 4.2 | 29.6 | GO:1900102 | negative regulation of endoplasmic reticulum unfolded protein response(GO:1900102) |
| 4.2 | 12.7 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 4.2 | 87.4 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 4.1 | 70.0 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 4.1 | 4.1 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
| 4.1 | 65.3 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 4.1 | 20.4 | GO:2000644 | regulation of receptor catabolic process(GO:2000644) negative regulation of receptor catabolic process(GO:2000645) |
| 4.1 | 4.1 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 4.1 | 60.9 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 4.0 | 4.0 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 4.0 | 1284.3 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 4.0 | 20.0 | GO:0035247 | peptidyl-arginine omega-N-methylation(GO:0035247) |
| 4.0 | 11.9 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 3.9 | 7.9 | GO:1903973 | negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) |
| 3.9 | 7.9 | GO:1904796 | regulation of core promoter binding(GO:1904796) |
| 3.9 | 27.3 | GO:0072642 | interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
| 3.9 | 35.0 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 3.9 | 27.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 3.9 | 11.6 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 3.9 | 255.0 | GO:0006413 | translational initiation(GO:0006413) |
| 3.9 | 7.7 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 3.8 | 11.5 | GO:1902905 | positive regulation of fibril organization(GO:1902905) |
| 3.8 | 30.7 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 3.8 | 22.7 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 3.8 | 15.0 | GO:0032079 | positive regulation of endodeoxyribonuclease activity(GO:0032079) |
| 3.7 | 7.5 | GO:1903978 | regulation of microglial cell activation(GO:1903978) |
| 3.7 | 37.3 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 3.7 | 7.4 | GO:0075509 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 3.7 | 259.9 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 3.7 | 14.8 | GO:0061724 | lipophagy(GO:0061724) |
| 3.7 | 11.1 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 3.7 | 51.5 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 3.6 | 10.9 | GO:1902966 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 3.6 | 43.7 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
| 3.6 | 90.4 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 3.6 | 21.4 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 3.6 | 14.2 | GO:0048105 | embryonic nail plate morphogenesis(GO:0035880) establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) |
| 3.5 | 21.2 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 3.5 | 10.6 | GO:1901805 | beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457) |
| 3.5 | 49.4 | GO:0030497 | fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 3.5 | 31.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 3.5 | 20.8 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 3.5 | 10.4 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 3.4 | 10.2 | GO:1901389 | regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389) |
| 3.4 | 20.3 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398) |
| 3.4 | 20.2 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
| 3.3 | 46.0 | GO:0044818 | mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818) |
| 3.3 | 9.8 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
| 3.2 | 16.2 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 3.2 | 58.2 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 3.2 | 6.4 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 3.2 | 25.6 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 3.2 | 25.6 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 3.2 | 16.0 | GO:0030242 | pexophagy(GO:0030242) |
| 3.2 | 22.3 | GO:2000576 | positive regulation of microtubule motor activity(GO:2000576) |
| 3.2 | 3.2 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 3.1 | 3.1 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 3.1 | 53.1 | GO:0006903 | vesicle targeting(GO:0006903) |
| 3.1 | 9.3 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 3.1 | 15.5 | GO:0039530 | MDA-5 signaling pathway(GO:0039530) |
| 3.1 | 52.3 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 3.1 | 122.1 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 3.1 | 12.2 | GO:0010636 | positive regulation of mitochondrial fusion(GO:0010636) |
| 3.0 | 6.1 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 3.0 | 30.4 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
| 3.0 | 9.1 | GO:0061163 | endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650) |
| 3.0 | 165.9 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 3.0 | 36.2 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 3.0 | 33.1 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 3.0 | 21.0 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 3.0 | 33.0 | GO:2000680 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 3.0 | 20.9 | GO:0051013 | microtubule severing(GO:0051013) |
| 3.0 | 17.9 | GO:0045338 | farnesyl diphosphate metabolic process(GO:0045338) |
| 3.0 | 32.7 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 3.0 | 8.9 | GO:0060739 | bud outgrowth involved in lung branching(GO:0060447) mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739) |
| 2.9 | 5.9 | GO:1903332 | regulation of protein folding(GO:1903332) |
| 2.9 | 35.0 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 2.9 | 14.4 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 2.9 | 20.0 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 2.9 | 85.8 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 2.9 | 11.4 | GO:0070433 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) |
| 2.9 | 2.9 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 2.9 | 2.9 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049) |
| 2.8 | 8.5 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 2.8 | 5.6 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 2.8 | 13.8 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 2.7 | 19.2 | GO:0061085 | regulation of histone H3-K27 methylation(GO:0061085) |
| 2.7 | 16.4 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 2.7 | 8.2 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 2.7 | 59.8 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 2.7 | 21.7 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 2.7 | 40.6 | GO:0043486 | histone exchange(GO:0043486) |
| 2.7 | 8.1 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 2.7 | 40.2 | GO:0006296 | nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) |
| 2.7 | 53.5 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 2.7 | 8.0 | GO:0035915 | pore formation in membrane of other organism(GO:0035915) |
| 2.6 | 15.8 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 2.6 | 34.2 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 2.6 | 28.9 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 2.6 | 23.6 | GO:0002934 | desmosome organization(GO:0002934) |
| 2.6 | 7.8 | GO:0019087 | transformation of host cell by virus(GO:0019087) |
| 2.6 | 18.3 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 2.6 | 7.8 | GO:0071500 | cellular response to nitrosative stress(GO:0071500) |
| 2.6 | 57.2 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 2.6 | 20.8 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 2.6 | 5.2 | GO:0098902 | regulation of membrane depolarization during action potential(GO:0098902) |
| 2.6 | 2.6 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 2.6 | 132.0 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 2.6 | 18.1 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 2.6 | 20.6 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 2.6 | 71.6 | GO:0072663 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 2.5 | 35.5 | GO:0071340 | skeletal muscle acetylcholine-gated channel clustering(GO:0071340) |
| 2.5 | 22.7 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 2.5 | 7.6 | GO:0021764 | amygdala development(GO:0021764) |
| 2.5 | 2.5 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 2.5 | 7.5 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 2.5 | 7.5 | GO:0071314 | cellular response to cocaine(GO:0071314) |
| 2.4 | 21.9 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 2.4 | 14.6 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 2.4 | 12.1 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 2.4 | 46.0 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 2.4 | 4.8 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 2.4 | 19.3 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 2.4 | 42.5 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 2.4 | 11.8 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 2.3 | 18.8 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 2.3 | 14.1 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 2.3 | 21.1 | GO:0071806 | protein transmembrane transport(GO:0071806) |
| 2.3 | 25.7 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 2.3 | 23.1 | GO:0051601 | exocyst localization(GO:0051601) |
| 2.3 | 18.3 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
| 2.3 | 6.8 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 2.3 | 15.8 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 2.2 | 6.7 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 2.2 | 53.0 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 2.2 | 22.1 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
| 2.2 | 15.4 | GO:0006116 | NADH oxidation(GO:0006116) |
| 2.2 | 6.6 | GO:0052501 | induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) |
| 2.2 | 6.6 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 2.2 | 17.5 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 2.2 | 6.5 | GO:0019285 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 2.2 | 34.8 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 2.1 | 36.4 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 2.1 | 19.3 | GO:0007619 | courtship behavior(GO:0007619) |
| 2.1 | 4.3 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 2.1 | 25.6 | GO:0070672 | response to interleukin-15(GO:0070672) |
| 2.1 | 6.4 | GO:0002572 | pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 2.1 | 10.7 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 2.1 | 14.8 | GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) |
| 2.1 | 14.8 | GO:0071352 | interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352) |
| 2.1 | 41.9 | GO:0006491 | N-glycan processing(GO:0006491) |
| 2.1 | 12.6 | GO:2000630 | positive regulation of miRNA metabolic process(GO:2000630) |
| 2.1 | 16.7 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 2.1 | 18.7 | GO:0015886 | heme transport(GO:0015886) |
| 2.1 | 10.3 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 2.0 | 18.4 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 2.0 | 8.1 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 2.0 | 6.1 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 2.0 | 22.3 | GO:2000347 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) positive regulation of hepatocyte proliferation(GO:2000347) |
| 2.0 | 4.0 | GO:0046349 | amino sugar biosynthetic process(GO:0046349) |
| 2.0 | 56.2 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 2.0 | 21.9 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
| 2.0 | 8.0 | GO:0030047 | actin modification(GO:0030047) |
| 2.0 | 7.9 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 2.0 | 7.9 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 2.0 | 5.9 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 1.9 | 25.3 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 1.9 | 1.9 | GO:0032252 | secretory granule localization(GO:0032252) |
| 1.9 | 19.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 1.9 | 3.9 | GO:1904398 | positive regulation of neuromuscular junction development(GO:1904398) |
| 1.9 | 23.0 | GO:0014870 | response to muscle inactivity(GO:0014870) |
| 1.9 | 9.6 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 1.9 | 15.3 | GO:1903543 | regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543) |
| 1.9 | 34.3 | GO:0097502 | mannosylation(GO:0097502) |
| 1.9 | 11.4 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 1.9 | 22.8 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
| 1.9 | 7.6 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 1.9 | 5.6 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 1.9 | 37.6 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 1.9 | 7.5 | GO:0000212 | meiotic spindle organization(GO:0000212) |
| 1.9 | 7.5 | GO:0033606 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
| 1.9 | 3.7 | GO:0050711 | negative regulation of interleukin-1 secretion(GO:0050711) negative regulation of interleukin-1 beta secretion(GO:0050713) |
| 1.8 | 9.2 | GO:0005997 | xylulose metabolic process(GO:0005997) |
| 1.8 | 9.2 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 1.8 | 12.9 | GO:0030473 | nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) |
| 1.8 | 36.7 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 1.8 | 76.8 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 1.8 | 16.4 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
| 1.8 | 7.3 | GO:0036229 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 1.8 | 5.4 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 1.8 | 5.4 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
| 1.8 | 7.1 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 1.8 | 24.8 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 1.8 | 23.0 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 1.8 | 3.5 | GO:0060296 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 1.8 | 8.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 1.8 | 8.8 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 1.8 | 73.7 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
| 1.8 | 3.5 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 1.7 | 29.7 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
| 1.7 | 17.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 1.7 | 15.7 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 1.7 | 52.2 | GO:0090383 | phagosome acidification(GO:0090383) |
| 1.7 | 43.3 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 1.7 | 8.7 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
| 1.7 | 26.0 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 1.7 | 5.2 | GO:0015822 | ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) |
| 1.7 | 5.1 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 1.7 | 18.7 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 1.7 | 25.4 | GO:0009226 | nucleotide-sugar biosynthetic process(GO:0009226) |
| 1.7 | 13.5 | GO:0035745 | T-helper 2 cell cytokine production(GO:0035745) |
| 1.7 | 116.4 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 1.7 | 23.6 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 1.7 | 3.4 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 1.7 | 5.0 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 1.7 | 21.6 | GO:0051642 | centrosome localization(GO:0051642) |
| 1.7 | 8.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 1.7 | 52.8 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 1.6 | 33.0 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 1.6 | 6.6 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 1.6 | 13.2 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 1.6 | 4.9 | GO:2001270 | regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 1.6 | 4.9 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 1.6 | 4.9 | GO:0009048 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 1.6 | 6.4 | GO:0090382 | phagosome maturation(GO:0090382) |
| 1.6 | 3.2 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
| 1.6 | 6.2 | GO:0070221 | sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) |
| 1.6 | 62.4 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 1.5 | 18.5 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 1.5 | 6.2 | GO:0046946 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 1.5 | 59.8 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 1.5 | 7.6 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 1.5 | 7.5 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 1.5 | 12.0 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 1.5 | 10.5 | GO:0044854 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) |
| 1.5 | 31.4 | GO:0006465 | signal peptide processing(GO:0006465) |
| 1.5 | 3.0 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 1.5 | 8.9 | GO:1990182 | exosomal secretion(GO:1990182) |
| 1.5 | 2.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 1.5 | 10.3 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 1.5 | 2.9 | GO:2000523 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 1.5 | 2.9 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 1.5 | 7.3 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 1.5 | 4.4 | GO:0030961 | peptidyl-arginine hydroxylation(GO:0030961) |
| 1.4 | 34.7 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 1.4 | 2.9 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 1.4 | 4.2 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 1.4 | 15.5 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 1.4 | 1.4 | GO:0060368 | regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) |
| 1.4 | 1.4 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 1.4 | 2.8 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 1.4 | 22.2 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 1.4 | 1.4 | GO:0043366 | beta selection(GO:0043366) |
| 1.4 | 6.8 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 1.3 | 6.7 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 1.3 | 17.4 | GO:0048569 | post-embryonic organ development(GO:0048569) |
| 1.3 | 2.7 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 1.3 | 7.9 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 1.3 | 11.9 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 1.3 | 23.7 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 1.3 | 10.5 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 1.3 | 3.9 | GO:0043320 | natural killer cell degranulation(GO:0043320) regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 1.3 | 17.0 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 1.3 | 5.2 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 1.3 | 11.6 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 1.3 | 14.2 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 1.3 | 7.5 | GO:0007296 | vitellogenesis(GO:0007296) |
| 1.3 | 5.0 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 1.2 | 6.0 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 1.2 | 8.4 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 1.2 | 15.6 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 1.2 | 7.2 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 1.2 | 55.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 1.2 | 15.2 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 1.2 | 13.9 | GO:1903539 | neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) protein localization to postsynaptic membrane(GO:1903539) establishment of protein localization to postsynaptic membrane(GO:1903540) |
| 1.2 | 1.2 | GO:0051944 | positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) |
| 1.2 | 1.2 | GO:1903625 | negative regulation of DNA catabolic process(GO:1903625) |
| 1.1 | 52.9 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 1.1 | 4.6 | GO:0032910 | transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) |
| 1.1 | 17.0 | GO:0019184 | nonribosomal peptide biosynthetic process(GO:0019184) |
| 1.1 | 2.3 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 1.1 | 3.4 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 1.1 | 3.3 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 1.1 | 4.4 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 1.1 | 42.6 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 1.1 | 2.2 | GO:0016128 | phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129) |
| 1.1 | 5.4 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 1.1 | 27.8 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 1.1 | 8.5 | GO:0034629 | cellular protein complex localization(GO:0034629) |
| 1.1 | 3.2 | GO:0036079 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 1.1 | 4.2 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 1.0 | 9.4 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 1.0 | 14.6 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 1.0 | 6.3 | GO:0090085 | regulation of protein deubiquitination(GO:0090085) |
| 1.0 | 4.1 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 1.0 | 6.2 | GO:0009249 | protein lipoylation(GO:0009249) |
| 1.0 | 5.2 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 1.0 | 3.1 | GO:0034553 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
| 1.0 | 10.2 | GO:0031639 | plasminogen activation(GO:0031639) |
| 1.0 | 4.1 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 1.0 | 11.3 | GO:0051665 | membrane raft localization(GO:0051665) |
| 1.0 | 1.0 | GO:0032070 | regulation of deoxyribonuclease activity(GO:0032070) |
| 1.0 | 19.4 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
| 1.0 | 6.9 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 1.0 | 4.0 | GO:1904977 | lymphatic endothelial cell migration(GO:1904977) |
| 1.0 | 3.9 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 1.0 | 8.7 | GO:0048311 | mitochondrion distribution(GO:0048311) |
| 1.0 | 6.7 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 1.0 | 1.9 | GO:0060406 | regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) |
| 0.9 | 2.8 | GO:0031550 | positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550) |
| 0.9 | 3.7 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 0.9 | 9.3 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.9 | 6.5 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.9 | 1.9 | GO:0045852 | pH elevation(GO:0045852) intracellular pH elevation(GO:0051454) |
| 0.9 | 6.5 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.9 | 36.9 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.9 | 0.9 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.9 | 3.7 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 0.9 | 2.7 | GO:0060957 | endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445) positive regulation of determination of dorsal identity(GO:2000017) |
| 0.9 | 2.7 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 0.9 | 4.5 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.9 | 2.7 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.9 | 17.1 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.9 | 2.7 | GO:0051444 | negative regulation of ubiquitin-protein transferase activity(GO:0051444) |
| 0.9 | 4.5 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.9 | 4.5 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 0.9 | 4.4 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.9 | 1.8 | GO:0061009 | common bile duct development(GO:0061009) |
| 0.9 | 8.8 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.9 | 4.3 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.9 | 2.6 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.9 | 3.4 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.8 | 3.3 | GO:0009440 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 0.8 | 11.6 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.8 | 4.1 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.8 | 9.0 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.8 | 4.9 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.8 | 52.4 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.8 | 19.6 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.8 | 3.2 | GO:0050916 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
| 0.8 | 0.8 | GO:0071609 | chemokine (C-C motif) ligand 5 production(GO:0071609) |
| 0.8 | 78.7 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.8 | 9.6 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.8 | 9.5 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.8 | 2.4 | GO:0048069 | eye pigmentation(GO:0048069) |
| 0.8 | 5.4 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.8 | 3.9 | GO:0070383 | DNA cytosine deamination(GO:0070383) |
| 0.8 | 6.9 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.8 | 4.6 | GO:0032462 | regulation of protein homooligomerization(GO:0032462) |
| 0.8 | 13.0 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.8 | 4.6 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
| 0.8 | 16.8 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.8 | 9.1 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.8 | 2.3 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.8 | 24.0 | GO:0042438 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
| 0.7 | 0.7 | GO:0048769 | sarcomerogenesis(GO:0048769) |
| 0.7 | 1.5 | GO:0070384 | Harderian gland development(GO:0070384) |
| 0.7 | 2.2 | GO:0097021 | lymphocyte migration into lymphoid organs(GO:0097021) |
| 0.7 | 5.0 | GO:0030421 | defecation(GO:0030421) |
| 0.7 | 7.2 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.7 | 3.5 | GO:0043247 | telomere maintenance in response to DNA damage(GO:0043247) |
| 0.7 | 0.7 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
| 0.7 | 1.4 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.7 | 2.8 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.7 | 9.0 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.7 | 0.7 | GO:0043307 | eosinophil activation(GO:0043307) |
| 0.7 | 5.5 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
| 0.7 | 1.4 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.7 | 4.1 | GO:0006548 | histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805) |
| 0.7 | 7.4 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
| 0.7 | 2.0 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 0.7 | 8.0 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.7 | 8.6 | GO:0048853 | forebrain morphogenesis(GO:0048853) |
| 0.6 | 3.9 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.6 | 8.4 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.6 | 3.2 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.6 | 1.9 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.6 | 23.9 | GO:0051289 | protein homotetramerization(GO:0051289) |
| 0.6 | 15.3 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
| 0.6 | 20.4 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.6 | 1.3 | GO:0061643 | chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643) |
| 0.6 | 1.9 | GO:0035739 | CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
| 0.6 | 3.8 | GO:0044362 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) modification by host of symbiont molecular function(GO:0052428) |
| 0.6 | 1.2 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.6 | 5.0 | GO:0005984 | disaccharide metabolic process(GO:0005984) |
| 0.6 | 1.2 | GO:0040031 | snRNA modification(GO:0040031) |
| 0.6 | 3.1 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.6 | 3.7 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.6 | 4.2 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
| 0.6 | 1.2 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 0.6 | 0.6 | GO:0061740 | protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) protein targeting to vacuole involved in autophagy(GO:0071211) |
| 0.6 | 4.2 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 0.6 | 1.8 | GO:0045554 | TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556) |
| 0.6 | 3.0 | GO:0006574 | valine catabolic process(GO:0006574) |
| 0.6 | 8.8 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.6 | 4.7 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.6 | 0.6 | GO:0060947 | cardiac vascular smooth muscle cell differentiation(GO:0060947) |
| 0.6 | 1.1 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.6 | 1.1 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.6 | 6.6 | GO:0071455 | cellular response to hyperoxia(GO:0071455) |
| 0.5 | 1.6 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.5 | 13.7 | GO:0030042 | actin filament depolymerization(GO:0030042) |
| 0.5 | 2.6 | GO:1990869 | response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) |
| 0.5 | 1.6 | GO:0070257 | regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257) |
| 0.5 | 4.1 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
| 0.5 | 2.5 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 0.5 | 17.9 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.5 | 2.4 | GO:0003070 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 0.5 | 1.9 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.5 | 6.2 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.5 | 3.3 | GO:0034724 | DNA replication-independent nucleosome organization(GO:0034724) |
| 0.5 | 8.9 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.5 | 1.4 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 0.5 | 13.2 | GO:0010259 | multicellular organism aging(GO:0010259) |
| 0.4 | 1.8 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.4 | 1.8 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.4 | 2.6 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.4 | 0.4 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
| 0.4 | 2.6 | GO:0015827 | tryptophan transport(GO:0015827) leucine import(GO:0060356) |
| 0.4 | 6.6 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.4 | 3.0 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.4 | 2.2 | GO:0048385 | regulation of retinoic acid receptor signaling pathway(GO:0048385) |
| 0.4 | 4.7 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.4 | 1.7 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.4 | 6.8 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.4 | 2.9 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.4 | 2.1 | GO:0015691 | cadmium ion transport(GO:0015691) lead ion transport(GO:0015692) cadmium ion transmembrane transport(GO:0070574) |
| 0.4 | 1.6 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.4 | 2.0 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.4 | 3.9 | GO:0032801 | receptor catabolic process(GO:0032801) |
| 0.4 | 2.8 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.4 | 0.4 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 0.4 | 1.9 | GO:1902659 | regulation of glucose mediated signaling pathway(GO:1902659) |
| 0.4 | 1.5 | GO:0042421 | norepinephrine biosynthetic process(GO:0042421) |
| 0.4 | 2.3 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.4 | 1.5 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
| 0.4 | 2.9 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.4 | 1.4 | GO:1903659 | regulation of complement-dependent cytotoxicity(GO:1903659) |
| 0.4 | 3.6 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.4 | 17.7 | GO:0048278 | vesicle docking(GO:0048278) |
| 0.4 | 0.7 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 0.4 | 1.1 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.4 | 3.5 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.3 | 2.1 | GO:1900426 | positive regulation of defense response to bacterium(GO:1900426) |
| 0.3 | 1.3 | GO:0071316 | cellular response to nicotine(GO:0071316) |
| 0.3 | 2.3 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.3 | 1.7 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.3 | 6.7 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
| 0.3 | 1.6 | GO:1990791 | dorsal root ganglion development(GO:1990791) |
| 0.3 | 1.9 | GO:1905123 | regulation of glucosylceramidase activity(GO:1905123) |
| 0.3 | 50.4 | GO:0006457 | protein folding(GO:0006457) |
| 0.3 | 1.6 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.3 | 16.4 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.3 | 7.7 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.3 | 1.9 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.3 | 1.8 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.3 | 11.8 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.3 | 3.2 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.3 | 3.5 | GO:0060561 | apoptotic process involved in morphogenesis(GO:0060561) |
| 0.3 | 1.4 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
| 0.3 | 0.9 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.3 | 4.6 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.3 | 0.6 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.3 | 1.1 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.3 | 1.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.3 | 3.0 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.3 | 1.6 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.3 | 1.4 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.3 | 1.3 | GO:0071502 | cellular response to temperature stimulus(GO:0071502) |
| 0.3 | 4.8 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.3 | 0.8 | GO:0046532 | regulation of photoreceptor cell differentiation(GO:0046532) |
| 0.3 | 2.0 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
| 0.3 | 1.5 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.3 | 0.8 | GO:0090656 | t-circle formation(GO:0090656) |
| 0.2 | 1.2 | GO:0071493 | cellular response to UV-B(GO:0071493) |
| 0.2 | 3.7 | GO:0001782 | B cell homeostasis(GO:0001782) |
| 0.2 | 2.9 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.2 | 11.9 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.2 | 2.4 | GO:0006787 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.2 | 1.7 | GO:0002260 | lymphocyte homeostasis(GO:0002260) |
| 0.2 | 2.6 | GO:0031958 | corticosteroid receptor signaling pathway(GO:0031958) |
| 0.2 | 1.2 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
| 0.2 | 0.9 | GO:1902715 | positive regulation of interferon-gamma secretion(GO:1902715) |
| 0.2 | 1.8 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.2 | 0.5 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.2 | 5.4 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.2 | 0.9 | GO:1903173 | phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173) |
| 0.2 | 1.1 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.2 | 2.2 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.2 | 6.6 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.2 | 0.6 | GO:0070857 | regulation of bile acid biosynthetic process(GO:0070857) |
| 0.2 | 1.9 | GO:1902170 | cellular response to reactive nitrogen species(GO:1902170) |
| 0.2 | 1.4 | GO:2000172 | regulation of branching morphogenesis of a nerve(GO:2000172) |
| 0.2 | 1.4 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.2 | 0.2 | GO:0060374 | mast cell differentiation(GO:0060374) |
| 0.2 | 5.2 | GO:0031100 | organ regeneration(GO:0031100) |
| 0.2 | 4.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.2 | 0.8 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.2 | 3.2 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.2 | 1.1 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.2 | 0.4 | GO:2000196 | positive regulation of female gonad development(GO:2000196) |
| 0.2 | 3.1 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.2 | 17.7 | GO:0046034 | ATP metabolic process(GO:0046034) |
| 0.2 | 0.9 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
| 0.2 | 0.5 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
| 0.2 | 4.3 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.2 | 5.9 | GO:0015893 | drug transport(GO:0015893) |
| 0.2 | 0.2 | GO:0060278 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.2 | 0.8 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.2 | 1.4 | GO:0048007 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.2 | 0.2 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 0.1 | 0.9 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 0.1 | GO:2001274 | negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
| 0.1 | 1.6 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
| 0.1 | 3.8 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.1 | 0.3 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 0.1 | 4.3 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.1 | 3.3 | GO:0007628 | adult walking behavior(GO:0007628) |
| 0.1 | 0.6 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 0.1 | 2.5 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.1 | 1.5 | GO:0014904 | myotube cell development(GO:0014904) |
| 0.1 | 0.8 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 0.8 | GO:0002154 | thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) |
| 0.1 | 3.5 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.1 | 0.5 | GO:0043305 | negative regulation of mast cell degranulation(GO:0043305) |
| 0.1 | 1.4 | GO:0006513 | protein monoubiquitination(GO:0006513) |
| 0.1 | 0.4 | GO:0042635 | positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798) |
| 0.1 | 1.2 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
| 0.1 | 1.4 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.1 | 1.2 | GO:0061298 | retina vasculature development in camera-type eye(GO:0061298) |
| 0.1 | 0.7 | GO:0032329 | serine transport(GO:0032329) |
| 0.1 | 1.5 | GO:0045086 | positive regulation of interleukin-2 biosynthetic process(GO:0045086) |
| 0.1 | 1.6 | GO:0006739 | NADP metabolic process(GO:0006739) |
| 0.1 | 0.8 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.5 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.1 | 0.3 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.1 | 0.4 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 0.1 | 0.3 | GO:0019321 | pentose metabolic process(GO:0019321) |
| 0.1 | 7.5 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.1 | 0.7 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.1 | 0.7 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.1 | 0.1 | GO:1904479 | negative regulation of intestinal absorption(GO:1904479) |
| 0.1 | 0.2 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.1 | 2.9 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.1 | 0.9 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.1 | 0.1 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.1 | 0.4 | GO:0016553 | base conversion or substitution editing(GO:0016553) |
| 0.1 | 0.1 | GO:1990637 | response to prolactin(GO:1990637) |
| 0.1 | 0.8 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) |
| 0.1 | 0.4 | GO:0015755 | response to fructose(GO:0009750) fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.1 | 0.1 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.1 | 0.2 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.1 | 0.2 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
| 0.0 | 0.3 | GO:0002717 | positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
| 0.0 | 0.1 | GO:1901376 | mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376) |
| 0.0 | 0.2 | GO:0003360 | brainstem development(GO:0003360) |
| 0.0 | 0.3 | GO:1901534 | positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534) |
| 0.0 | 0.2 | GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949) |
| 0.0 | 0.3 | GO:1901889 | negative regulation of cell junction assembly(GO:1901889) |
| 0.0 | 0.5 | GO:2001244 | positive regulation of intrinsic apoptotic signaling pathway(GO:2001244) |
| 0.0 | 0.8 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.3 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.3 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.0 | 0.1 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
| 0.0 | 0.2 | GO:0048747 | muscle fiber development(GO:0048747) |
| 0.0 | 0.4 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
| 0.0 | 0.0 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
| 0.0 | 0.1 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.0 | 0.2 | GO:0031290 | retinal ganglion cell axon guidance(GO:0031290) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 58.4 | 584.0 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 56.7 | 170.0 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 55.5 | 277.7 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 48.8 | 341.5 | GO:0005683 | U7 snRNP(GO:0005683) |
| 41.7 | 41.7 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 39.4 | 157.7 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 32.6 | 163.0 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 31.8 | 318.0 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 30.8 | 369.0 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 30.4 | 182.4 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 29.8 | 89.4 | GO:0018444 | translation release factor complex(GO:0018444) |
| 29.6 | 177.5 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 29.3 | 146.7 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 29.0 | 202.7 | GO:0032021 | NELF complex(GO:0032021) |
| 27.4 | 355.6 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 25.7 | 102.9 | GO:0071920 | cleavage body(GO:0071920) |
| 25.1 | 50.2 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 24.9 | 174.2 | GO:0090661 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 23.4 | 70.3 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 22.7 | 113.6 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 21.3 | 213.0 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 21.2 | 275.6 | GO:0005688 | U6 snRNP(GO:0005688) |
| 20.8 | 166.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 20.6 | 82.3 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 20.4 | 81.7 | GO:0071986 | Ragulator complex(GO:0071986) |
| 20.3 | 671.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 20.3 | 223.4 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 19.5 | 175.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 19.2 | 268.7 | GO:0005686 | U2 snRNP(GO:0005686) |
| 19.2 | 172.5 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 18.8 | 263.6 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 18.7 | 18.7 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 18.6 | 55.9 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 18.5 | 314.5 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 18.3 | 109.9 | GO:0034709 | methylosome(GO:0034709) |
| 17.9 | 35.7 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 17.7 | 141.3 | GO:0000796 | condensin complex(GO:0000796) |
| 17.6 | 105.9 | GO:0061617 | MICOS complex(GO:0061617) |
| 17.5 | 104.8 | GO:0071797 | LUBAC complex(GO:0071797) |
| 17.3 | 104.1 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 17.3 | 138.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 17.2 | 51.5 | GO:0071817 | MMXD complex(GO:0071817) |
| 17.1 | 153.8 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 17.0 | 271.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 16.5 | 164.6 | GO:0097255 | R2TP complex(GO:0097255) |
| 16.3 | 48.9 | GO:0097441 | basilar dendrite(GO:0097441) |
| 15.8 | 79.0 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 15.6 | 312.2 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 15.2 | 167.6 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 15.1 | 60.4 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 15.1 | 75.4 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 14.8 | 133.3 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 14.2 | 184.8 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 14.1 | 127.1 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 14.1 | 98.5 | GO:0016272 | prefoldin complex(GO:0016272) |
| 13.8 | 165.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 13.4 | 376.4 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 13.3 | 106.5 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 13.3 | 39.8 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 13.2 | 516.6 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 13.2 | 317.0 | GO:0030686 | 90S preribosome(GO:0030686) |
| 13.1 | 223.1 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 13.0 | 233.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 12.5 | 49.9 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 12.2 | 48.7 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 11.9 | 35.8 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
| 11.9 | 35.6 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 11.7 | 93.8 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 11.6 | 11.6 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 11.6 | 81.1 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 11.5 | 57.3 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 11.4 | 34.3 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 11.3 | 33.9 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 11.0 | 187.7 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 11.0 | 55.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 10.8 | 107.8 | GO:0070552 | BRISC complex(GO:0070552) |
| 10.7 | 75.1 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 10.6 | 74.1 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 10.5 | 31.4 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
| 10.1 | 40.5 | GO:0070876 | SOSS complex(GO:0070876) |
| 10.0 | 30.0 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 10.0 | 10.0 | GO:0031261 | GINS complex(GO:0000811) DNA replication preinitiation complex(GO:0031261) |
| 9.9 | 149.0 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 9.8 | 49.0 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 9.7 | 448.1 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 9.7 | 979.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 9.6 | 57.6 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 9.5 | 19.1 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 9.5 | 161.8 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 9.3 | 46.7 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 9.3 | 46.5 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 9.2 | 129.5 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 9.2 | 27.7 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 9.2 | 18.4 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 9.2 | 128.3 | GO:0032040 | small-subunit processome(GO:0032040) |
| 9.0 | 72.3 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 8.8 | 106.2 | GO:0042555 | MCM complex(GO:0042555) |
| 8.8 | 26.3 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 8.7 | 104.6 | GO:0071203 | WASH complex(GO:0071203) |
| 8.7 | 78.3 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 8.7 | 26.0 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 8.7 | 34.7 | GO:1990423 | RZZ complex(GO:1990423) |
| 8.6 | 111.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 8.3 | 91.3 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 8.2 | 49.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 8.2 | 41.2 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 8.2 | 57.4 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 8.2 | 90.1 | GO:0070449 | elongin complex(GO:0070449) |
| 8.2 | 16.3 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 8.1 | 40.7 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 8.1 | 89.4 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 8.1 | 97.1 | GO:0030008 | TRAPP complex(GO:0030008) |
| 8.0 | 32.1 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 7.9 | 222.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 7.9 | 31.7 | GO:0022624 | proteasome accessory complex(GO:0022624) |
| 7.8 | 23.5 | GO:1990298 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 7.7 | 7.7 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 7.6 | 68.0 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 7.4 | 37.1 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 7.4 | 14.8 | GO:0035061 | interchromatin granule(GO:0035061) |
| 7.0 | 352.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 7.0 | 76.7 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 6.9 | 20.8 | GO:0032419 | extrinsic component of lysosome membrane(GO:0032419) |
| 6.9 | 397.7 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 6.7 | 147.3 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 6.7 | 33.3 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 6.5 | 91.2 | GO:0005685 | U1 snRNP(GO:0005685) |
| 6.5 | 58.5 | GO:0042382 | paraspeckles(GO:0042382) |
| 6.5 | 32.4 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 6.5 | 19.4 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 6.4 | 25.8 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 6.3 | 31.4 | GO:0045273 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 6.3 | 94.0 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 6.2 | 18.7 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 6.2 | 24.8 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 6.2 | 12.3 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 6.1 | 55.1 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 6.1 | 24.4 | GO:0031211 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 6.0 | 6.0 | GO:0000346 | transcription export complex(GO:0000346) |
| 5.7 | 45.7 | GO:0000322 | storage vacuole(GO:0000322) |
| 5.6 | 28.2 | GO:0005839 | proteasome core complex(GO:0005839) |
| 5.5 | 55.5 | GO:0043203 | axon hillock(GO:0043203) |
| 5.5 | 22.2 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 5.5 | 38.4 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 5.5 | 10.9 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 5.5 | 16.4 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 5.4 | 59.8 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 5.4 | 10.8 | GO:0071010 | prespliceosome(GO:0071010) |
| 5.3 | 21.2 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
| 5.3 | 333.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 5.3 | 15.8 | GO:0034271 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 5.2 | 114.6 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 5.2 | 134.2 | GO:0036452 | ESCRT complex(GO:0036452) |
| 5.1 | 15.4 | GO:0000805 | X chromosome(GO:0000805) |
| 5.1 | 45.8 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 5.0 | 35.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 5.0 | 44.6 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 4.9 | 58.8 | GO:0090543 | Flemming body(GO:0090543) |
| 4.8 | 9.6 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 4.7 | 14.2 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 4.6 | 106.9 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 4.6 | 69.0 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 4.6 | 18.3 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 4.5 | 9.1 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 4.5 | 22.4 | GO:0032044 | DSIF complex(GO:0032044) |
| 4.5 | 44.9 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 4.4 | 65.8 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 4.4 | 43.6 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 4.3 | 21.6 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 4.3 | 21.4 | GO:0000124 | SAGA complex(GO:0000124) |
| 4.2 | 17.0 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 4.2 | 29.6 | GO:0044391 | ribosomal subunit(GO:0044391) |
| 4.2 | 21.0 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 4.2 | 71.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 4.2 | 29.4 | GO:0030677 | ribonuclease P complex(GO:0030677) |
| 4.2 | 62.7 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 4.1 | 61.0 | GO:0000812 | Swr1 complex(GO:0000812) INO80-type complex(GO:0097346) |
| 4.1 | 73.2 | GO:0032433 | filopodium tip(GO:0032433) |
| 4.0 | 56.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 4.0 | 24.0 | GO:0030891 | VCB complex(GO:0030891) |
| 3.9 | 35.4 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 3.9 | 19.5 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 3.8 | 19.2 | GO:0089701 | U2AF(GO:0089701) |
| 3.8 | 38.3 | GO:0032039 | integrator complex(GO:0032039) |
| 3.8 | 18.8 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 3.8 | 90.2 | GO:0005657 | replication fork(GO:0005657) |
| 3.7 | 332.3 | GO:0005643 | nuclear pore(GO:0005643) |
| 3.7 | 165.8 | GO:0090544 | BAF-type complex(GO:0090544) |
| 3.6 | 14.5 | GO:0001939 | female pronucleus(GO:0001939) |
| 3.6 | 188.8 | GO:0005840 | ribosome(GO:0005840) |
| 3.5 | 42.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 3.5 | 578.6 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 3.4 | 186.3 | GO:0005871 | kinesin complex(GO:0005871) |
| 3.4 | 16.9 | GO:0008274 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 3.4 | 37.1 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 3.4 | 23.6 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 3.3 | 36.8 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 3.3 | 16.7 | GO:0097422 | tubular endosome(GO:0097422) |
| 3.3 | 39.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 3.2 | 12.9 | GO:0016589 | NURF complex(GO:0016589) |
| 3.2 | 44.9 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 3.1 | 12.6 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 3.1 | 6.1 | GO:0032059 | bleb(GO:0032059) |
| 3.0 | 54.9 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 3.0 | 21.2 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 3.0 | 21.0 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 3.0 | 9.0 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 3.0 | 8.9 | GO:0097409 | glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038) |
| 3.0 | 14.8 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 3.0 | 5.9 | GO:0097443 | sorting endosome(GO:0097443) |
| 2.9 | 5.9 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 2.9 | 64.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 2.8 | 212.6 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 2.8 | 2.8 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 2.8 | 231.4 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 2.7 | 56.5 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 2.7 | 16.1 | GO:0020016 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 2.7 | 16.1 | GO:0005642 | annulate lamellae(GO:0005642) |
| 2.7 | 132.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 2.6 | 58.1 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 2.6 | 5.1 | GO:0071439 | clathrin complex(GO:0071439) |
| 2.5 | 33.1 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 2.5 | 25.1 | GO:1902555 | endoribonuclease complex(GO:1902555) |
| 2.5 | 29.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 2.4 | 14.6 | GO:0034518 | RNA cap binding complex(GO:0034518) |
| 2.4 | 24.2 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 2.4 | 9.5 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 2.4 | 2.4 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 2.4 | 16.5 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 2.3 | 16.4 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 2.3 | 111.2 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 2.3 | 11.6 | GO:0031332 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 2.3 | 9.1 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 2.3 | 6.8 | GO:0033167 | ARC complex(GO:0033167) |
| 2.3 | 275.5 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 2.2 | 74.1 | GO:0016469 | proton-transporting two-sector ATPase complex(GO:0016469) |
| 2.2 | 26.5 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 2.2 | 309.3 | GO:0000793 | condensed chromosome(GO:0000793) |
| 2.2 | 4.4 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 2.2 | 6.6 | GO:0097452 | GAIT complex(GO:0097452) |
| 2.1 | 10.4 | GO:0031523 | Myb complex(GO:0031523) |
| 1.9 | 7.7 | GO:0044307 | dendritic branch(GO:0044307) |
| 1.9 | 17.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 1.9 | 15.3 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 1.8 | 369.0 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 1.8 | 5.4 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 1.7 | 130.2 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 1.7 | 6.8 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 1.7 | 1.7 | GO:0005955 | calcineurin complex(GO:0005955) |
| 1.7 | 24.9 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 1.7 | 76.1 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 1.6 | 19.2 | GO:0035861 | site of double-strand break(GO:0035861) |
| 1.6 | 12.6 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 1.6 | 31.4 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 1.5 | 146.7 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 1.5 | 53.4 | GO:0016235 | aggresome(GO:0016235) |
| 1.5 | 143.5 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 1.5 | 7.4 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 1.5 | 11.8 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
| 1.5 | 59.6 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 1.4 | 24.6 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 1.4 | 4.3 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 1.4 | 12.7 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 1.4 | 2.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 1.4 | 31.9 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 1.3 | 48.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 1.3 | 5.3 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 1.3 | 12.9 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 1.3 | 15.4 | GO:0016580 | Sin3 complex(GO:0016580) |
| 1.3 | 6.4 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 1.3 | 10.2 | GO:1905202 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 1.3 | 30.4 | GO:0000502 | proteasome complex(GO:0000502) |
| 1.2 | 52.9 | GO:0001772 | immunological synapse(GO:0001772) |
| 1.2 | 56.5 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 1.2 | 16.5 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 1.2 | 3.5 | GO:0001652 | granular component(GO:0001652) |
| 1.2 | 86.9 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 1.1 | 1.1 | GO:0097342 | ripoptosome(GO:0097342) |
| 1.1 | 135.4 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 1.1 | 17.0 | GO:0031932 | TORC2 complex(GO:0031932) TOR complex(GO:0038201) |
| 1.1 | 13.5 | GO:0030904 | retromer complex(GO:0030904) |
| 1.1 | 4.4 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 1.1 | 5.4 | GO:0032432 | actin filament bundle(GO:0032432) |
| 1.1 | 23.4 | GO:0030120 | vesicle coat(GO:0030120) |
| 1.1 | 3.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 1.0 | 10.5 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 1.0 | 6.3 | GO:0044754 | autolysosome(GO:0044754) |
| 1.0 | 35.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 1.0 | 10.2 | GO:0044292 | dendrite terminus(GO:0044292) |
| 1.0 | 13.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 1.0 | 3.0 | GO:0032592 | integral component of mitochondrial membrane(GO:0032592) |
| 1.0 | 18.1 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 1.0 | 4.0 | GO:0002945 | cyclin K-CDK13 complex(GO:0002945) |
| 1.0 | 7.9 | GO:0070852 | cell body fiber(GO:0070852) |
| 1.0 | 2.9 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.9 | 26.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.9 | 103.3 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.9 | 2.7 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.9 | 29.4 | GO:0045095 | keratin filament(GO:0045095) |
| 0.9 | 15.6 | GO:0042827 | platelet dense granule(GO:0042827) |
| 0.9 | 18.0 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.8 | 7.5 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.8 | 5.8 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.8 | 1038.2 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.8 | 6.4 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.7 | 4.5 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.7 | 1.5 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.7 | 2.8 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.7 | 7.8 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.6 | 5.2 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.6 | 3.2 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.6 | 1.2 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.6 | 28.8 | GO:0005776 | autophagosome(GO:0005776) |
| 0.6 | 19.7 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.6 | 3.0 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.6 | 8.1 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.6 | 5.2 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.6 | 6.2 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.5 | 3.2 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.5 | 1.6 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.5 | 0.5 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.5 | 12.5 | GO:0032994 | protein-lipid complex(GO:0032994) |
| 0.5 | 11.6 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.5 | 1.9 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.5 | 4.2 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.5 | 8.3 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.5 | 17.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.4 | 2.6 | GO:0060171 | stereocilium membrane(GO:0060171) |
| 0.4 | 1.3 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 0.4 | 1.6 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.4 | 3.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.4 | 4.8 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.4 | 140.9 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.4 | 45.9 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.3 | 2.1 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.3 | 12.7 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.3 | 1.3 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.3 | 6.9 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.3 | 1.1 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.3 | 10.8 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.3 | 21.5 | GO:0005903 | brush border(GO:0005903) |
| 0.2 | 7.8 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.2 | 8.0 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.2 | 1.4 | GO:0070554 | synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.2 | 503.9 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.2 | 3.4 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.2 | 1.6 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.2 | 4.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 7.8 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.2 | 9.9 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.2 | 3.2 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.2 | 0.5 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.1 | 1.7 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.1 | 0.1 | GO:0070522 | ERCC4-ERCC1 complex(GO:0070522) |
| 0.1 | 1.5 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 0.9 | GO:0030057 | desmosome(GO:0030057) |
| 0.1 | 1.9 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 0.7 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 35.5 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 0.4 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 0.2 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.1 | 0.2 | GO:0005600 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.1 | 0.2 | GO:0051286 | cell tip(GO:0051286) |
| 0.1 | 0.6 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 0.1 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.0 | 0.4 | GO:0000145 | exocyst(GO:0000145) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 56.7 | 170.0 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 52.0 | 156.0 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 41.6 | 124.7 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 39.9 | 119.7 | GO:0047693 | GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693) |
| 38.6 | 308.7 | GO:0070990 | snRNP binding(GO:0070990) |
| 31.1 | 93.2 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 30.7 | 92.0 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 29.5 | 88.4 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 29.3 | 146.7 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 28.9 | 86.7 | GO:0070259 | tyrosyl-DNA phosphodiesterase activity(GO:0070259) |
| 28.7 | 258.4 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 27.0 | 81.1 | GO:0034416 | bisphosphoglycerate phosphatase activity(GO:0034416) |
| 25.8 | 77.4 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
| 25.7 | 179.7 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 24.9 | 174.2 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 24.5 | 97.8 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 24.4 | 195.4 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 23.4 | 164.0 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 23.2 | 115.9 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 22.7 | 113.5 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 22.3 | 624.1 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 22.0 | 66.0 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 21.7 | 130.0 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 21.4 | 128.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 21.3 | 170.4 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 21.3 | 63.8 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 20.8 | 83.3 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 20.8 | 166.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 20.6 | 82.5 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 20.3 | 182.8 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 20.3 | 101.3 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 20.2 | 222.5 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 19.4 | 97.0 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 19.1 | 114.7 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 18.4 | 55.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 18.3 | 109.9 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 17.9 | 125.1 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 17.6 | 70.3 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 17.5 | 52.6 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 17.2 | 103.1 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 17.0 | 153.2 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 17.0 | 271.3 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 16.7 | 133.3 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 16.6 | 49.7 | GO:0004638 | phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639) |
| 16.1 | 176.6 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) |
| 15.7 | 187.8 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 15.5 | 31.0 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 15.3 | 45.9 | GO:0047315 | kynurenine-glyoxylate transaminase activity(GO:0047315) |
| 15.1 | 60.4 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 14.9 | 104.3 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 13.8 | 207.1 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 13.7 | 136.7 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 13.5 | 53.9 | GO:0070363 | mitochondrial light strand promoter sense binding(GO:0070363) |
| 13.2 | 39.7 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 12.8 | 243.6 | GO:0043495 | protein anchor(GO:0043495) |
| 12.7 | 38.1 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 12.6 | 37.9 | GO:0080023 | 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023) |
| 12.5 | 263.1 | GO:0000339 | RNA cap binding(GO:0000339) |
| 12.3 | 73.7 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 12.2 | 48.7 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 12.1 | 738.3 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 12.1 | 36.3 | GO:0055100 | adiponectin binding(GO:0055100) |
| 11.9 | 59.5 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 11.8 | 35.3 | GO:0015137 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 11.7 | 35.1 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 11.4 | 182.9 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 11.4 | 34.1 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
| 11.3 | 22.6 | GO:0000035 | acyl binding(GO:0000035) |
| 11.3 | 67.5 | GO:0008732 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 11.0 | 66.2 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 10.5 | 52.6 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 10.4 | 72.8 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 10.3 | 123.9 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 10.2 | 20.4 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 9.9 | 39.7 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 9.9 | 29.6 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 9.8 | 29.5 | GO:0031753 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 9.8 | 127.5 | GO:0030515 | snoRNA binding(GO:0030515) |
| 9.8 | 58.7 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 9.8 | 48.8 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 9.7 | 58.2 | GO:0016748 | succinyltransferase activity(GO:0016748) |
| 9.6 | 28.9 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 9.6 | 38.4 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 9.5 | 362.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 9.5 | 199.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 9.4 | 1945.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 9.3 | 74.7 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 9.3 | 27.8 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 9.2 | 9.2 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 9.2 | 27.6 | GO:0031403 | lithium ion binding(GO:0031403) |
| 9.2 | 36.8 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 9.2 | 64.2 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 9.2 | 55.0 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 9.1 | 45.7 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 9.0 | 35.9 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 9.0 | 71.7 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 8.9 | 26.6 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 8.8 | 166.3 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 8.7 | 69.9 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 8.7 | 244.4 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 8.7 | 43.6 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 8.7 | 26.1 | GO:0042947 | glucoside transmembrane transporter activity(GO:0042947) |
| 8.5 | 25.4 | GO:0008670 | 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) |
| 8.4 | 33.7 | GO:0008312 | 7S RNA binding(GO:0008312) |
| 8.4 | 25.1 | GO:0071566 | UFM1 activating enzyme activity(GO:0071566) |
| 8.4 | 50.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 8.3 | 175.2 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 8.3 | 16.7 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
| 7.8 | 39.2 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 7.8 | 148.8 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 7.7 | 23.1 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 7.7 | 277.3 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 7.6 | 38.1 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 7.6 | 60.8 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 7.5 | 15.1 | GO:0070336 | flap-structured DNA binding(GO:0070336) |
| 7.5 | 37.6 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 7.5 | 15.0 | GO:0034046 | poly(G) binding(GO:0034046) |
| 7.5 | 29.9 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 7.4 | 134.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 7.4 | 37.2 | GO:0004161 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 7.4 | 22.2 | GO:0035731 | S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731) |
| 7.3 | 95.5 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 7.3 | 36.4 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 7.2 | 239.1 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 7.2 | 158.6 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 7.2 | 337.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 7.1 | 35.7 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 7.0 | 308.5 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 6.9 | 20.8 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 6.9 | 20.6 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 6.8 | 20.3 | GO:0003978 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 6.7 | 26.9 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 6.7 | 60.4 | GO:0089720 | caspase binding(GO:0089720) |
| 6.7 | 93.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 6.6 | 59.6 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 6.6 | 26.5 | GO:0047676 | arachidonate-CoA ligase activity(GO:0047676) |
| 6.6 | 13.2 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 6.5 | 51.9 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 6.5 | 51.9 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 6.4 | 96.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 6.4 | 19.2 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 6.3 | 18.9 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 6.3 | 12.6 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 6.3 | 18.8 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 6.2 | 131.2 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 6.1 | 6.1 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 6.1 | 157.9 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 6.0 | 18.1 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 5.9 | 47.6 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 5.9 | 5.9 | GO:0032404 | mismatch repair complex binding(GO:0032404) |
| 5.8 | 145.8 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 5.8 | 34.9 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 5.8 | 17.4 | GO:0003896 | DNA primase activity(GO:0003896) |
| 5.8 | 28.9 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 5.8 | 34.6 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 5.8 | 23.1 | GO:0004146 | dihydrofolate reductase activity(GO:0004146) |
| 5.7 | 142.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 5.7 | 22.7 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 5.6 | 16.9 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 5.6 | 22.5 | GO:0008469 | histone-arginine N-methyltransferase activity(GO:0008469) |
| 5.6 | 22.4 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 5.6 | 16.8 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 5.5 | 16.6 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 5.5 | 22.0 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 5.4 | 16.3 | GO:0000104 | succinate dehydrogenase activity(GO:0000104) |
| 5.4 | 53.8 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
| 5.3 | 21.4 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 5.2 | 20.9 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 5.2 | 10.4 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) |
| 5.2 | 15.6 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 5.2 | 41.4 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 5.2 | 15.5 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 5.1 | 5.1 | GO:0004549 | tRNA-specific ribonuclease activity(GO:0004549) |
| 5.1 | 20.5 | GO:0004360 | glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) |
| 5.1 | 5.1 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) |
| 5.0 | 5.0 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 5.0 | 35.3 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 5.0 | 15.1 | GO:0033989 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594) |
| 5.0 | 10.0 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 5.0 | 139.7 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 4.9 | 59.2 | GO:0031386 | protein tag(GO:0031386) |
| 4.9 | 560.8 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 4.9 | 34.0 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 4.8 | 19.4 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 4.8 | 28.6 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 4.8 | 38.0 | GO:0015288 | porin activity(GO:0015288) |
| 4.8 | 128.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 4.7 | 18.6 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 4.6 | 46.0 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 4.6 | 27.6 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 4.6 | 4.6 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 4.6 | 18.3 | GO:0048256 | flap endonuclease activity(GO:0048256) |
| 4.5 | 36.2 | GO:0050733 | RS domain binding(GO:0050733) |
| 4.5 | 18.0 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 4.5 | 220.0 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 4.5 | 17.8 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 4.5 | 26.7 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 4.4 | 13.3 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 4.4 | 4.4 | GO:0032551 | pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 4.4 | 8.8 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 4.4 | 21.9 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 4.4 | 26.2 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 4.3 | 8.7 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 4.3 | 26.1 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 4.3 | 17.3 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 4.3 | 30.3 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 4.3 | 68.9 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 4.3 | 17.2 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 4.3 | 98.6 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 4.2 | 17.0 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 4.1 | 20.3 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 4.1 | 174.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 4.1 | 12.2 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 4.0 | 113.2 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 4.0 | 36.3 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 4.0 | 20.0 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 4.0 | 27.9 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 3.9 | 7.9 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 3.9 | 15.8 | GO:0102345 | 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345) |
| 3.9 | 35.4 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 3.9 | 78.5 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 3.9 | 15.5 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 3.9 | 30.9 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 3.8 | 80.1 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 3.8 | 18.9 | GO:0031544 | peptidyl-proline 3-dioxygenase activity(GO:0031544) |
| 3.8 | 207.1 | GO:0008186 | RNA-dependent ATPase activity(GO:0008186) |
| 3.7 | 37.4 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 3.7 | 418.3 | GO:0008565 | protein transporter activity(GO:0008565) |
| 3.7 | 22.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 3.7 | 118.1 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 3.7 | 14.7 | GO:0032557 | pyrimidine ribonucleotide binding(GO:0032557) |
| 3.6 | 273.1 | GO:0019003 | GDP binding(GO:0019003) |
| 3.6 | 32.7 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 3.6 | 53.7 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 3.6 | 10.7 | GO:0002046 | opsin binding(GO:0002046) |
| 3.5 | 14.0 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 3.5 | 69.9 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 3.5 | 10.4 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 3.5 | 83.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 3.4 | 17.1 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 3.4 | 43.9 | GO:0031489 | myosin V binding(GO:0031489) |
| 3.4 | 10.1 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 3.3 | 10.0 | GO:0000252 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012) |
| 3.3 | 3.3 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 3.3 | 167.0 | GO:0031491 | nucleosome binding(GO:0031491) |
| 3.3 | 6.5 | GO:0016212 | kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) |
| 3.2 | 16.1 | GO:0004905 | type I interferon receptor activity(GO:0004905) |
| 3.2 | 9.6 | GO:0001034 | RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034) |
| 3.2 | 15.9 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 3.2 | 9.5 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 3.1 | 12.3 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 3.0 | 9.0 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 3.0 | 20.9 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 3.0 | 38.8 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 3.0 | 17.9 | GO:0051996 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 2.9 | 8.7 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 2.9 | 14.3 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
| 2.9 | 5.7 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 2.8 | 150.7 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 2.8 | 17.0 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
| 2.8 | 133.3 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 2.8 | 25.4 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 2.8 | 11.2 | GO:0043515 | kinetochore binding(GO:0043515) |
| 2.8 | 8.3 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 2.8 | 25.0 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 2.8 | 72.1 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 2.8 | 16.5 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 2.7 | 13.7 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 2.7 | 38.5 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 2.7 | 13.6 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 2.7 | 45.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 2.6 | 7.9 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
| 2.6 | 7.8 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 2.6 | 28.7 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 2.6 | 5.2 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 2.6 | 165.2 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 2.6 | 10.3 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 2.6 | 38.3 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 2.5 | 12.7 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 2.5 | 32.9 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
| 2.5 | 5.0 | GO:0000182 | rDNA binding(GO:0000182) |
| 2.5 | 20.1 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 2.5 | 12.6 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 2.5 | 15.1 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 2.5 | 7.5 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 2.5 | 9.9 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 2.5 | 64.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 2.5 | 17.4 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 2.4 | 17.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 2.4 | 4.9 | GO:0016418 | S-acetyltransferase activity(GO:0016418) |
| 2.4 | 16.9 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 2.4 | 7.2 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
| 2.4 | 32.9 | GO:0048156 | tau protein binding(GO:0048156) |
| 2.3 | 18.7 | GO:0015232 | heme transporter activity(GO:0015232) |
| 2.3 | 16.3 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 2.3 | 11.3 | GO:0036033 | mediator complex binding(GO:0036033) |
| 2.2 | 6.7 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 2.2 | 115.5 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 2.2 | 6.6 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
| 2.2 | 19.8 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 2.2 | 6.6 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 2.2 | 28.5 | GO:0043531 | ADP binding(GO:0043531) |
| 2.2 | 17.5 | GO:0071253 | connexin binding(GO:0071253) |
| 2.2 | 15.3 | GO:0004470 | malic enzyme activity(GO:0004470) |
| 2.2 | 67.4 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 2.1 | 4.3 | GO:0048039 | ubiquinone binding(GO:0048039) |
| 2.1 | 8.5 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 2.1 | 6.4 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
| 2.1 | 21.3 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 2.1 | 4.2 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 2.1 | 10.6 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 2.1 | 8.5 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 2.1 | 133.1 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 2.1 | 8.4 | GO:0015315 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 2.1 | 10.4 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 2.1 | 10.4 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 2.1 | 6.2 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
| 2.0 | 14.2 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 2.0 | 2.0 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 2.0 | 270.4 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 2.0 | 15.9 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 2.0 | 15.9 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 2.0 | 33.7 | GO:0051400 | BH domain binding(GO:0051400) |
| 2.0 | 7.9 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 2.0 | 13.8 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 2.0 | 13.7 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 1.9 | 42.4 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 1.9 | 21.1 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 1.9 | 53.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 1.9 | 20.8 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 1.9 | 17.0 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 1.9 | 9.3 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 1.8 | 5.5 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 1.8 | 12.9 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 1.8 | 12.7 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 1.8 | 63.4 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 1.8 | 7.2 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 1.8 | 326.8 | GO:0051015 | actin filament binding(GO:0051015) |
| 1.8 | 33.8 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 1.8 | 5.3 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 1.8 | 88.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 1.8 | 5.3 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 1.8 | 14.1 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 1.7 | 5.2 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
| 1.7 | 5.1 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 1.7 | 5.0 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 1.7 | 6.6 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 1.6 | 24.7 | GO:0070628 | proteasome binding(GO:0070628) |
| 1.6 | 78.5 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 1.6 | 27.7 | GO:0031404 | chloride ion binding(GO:0031404) |
| 1.6 | 32.5 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 1.6 | 3.2 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 1.6 | 14.5 | GO:0001614 | purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) |
| 1.6 | 9.7 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 1.6 | 4.8 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 1.6 | 20.8 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 1.6 | 580.9 | GO:0045296 | cadherin binding(GO:0045296) |
| 1.6 | 1.6 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 1.5 | 6.2 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 1.5 | 74.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 1.5 | 7.5 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 1.5 | 8.9 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 1.5 | 1.5 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 1.5 | 29.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 1.5 | 4.4 | GO:0052839 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 1.5 | 54.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 1.4 | 25.8 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 1.4 | 35.6 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 1.4 | 49.9 | GO:0005123 | death receptor binding(GO:0005123) |
| 1.4 | 52.4 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 1.4 | 1.4 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 1.4 | 14.1 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 1.3 | 28.0 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 1.3 | 6.6 | GO:1990254 | keratin filament binding(GO:1990254) |
| 1.3 | 9.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 1.3 | 15.7 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 1.3 | 1507.9 | GO:0003723 | RNA binding(GO:0003723) |
| 1.3 | 12.9 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 1.3 | 2.6 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 1.3 | 10.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 1.3 | 10.2 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 1.3 | 8.9 | GO:0045545 | syndecan binding(GO:0045545) |
| 1.3 | 7.6 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 1.2 | 7.4 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 1.2 | 6.1 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 1.2 | 18.0 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 1.2 | 5.9 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 1.2 | 10.6 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
| 1.2 | 12.9 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 1.2 | 10.4 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 1.2 | 9.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 1.1 | 14.9 | GO:0019213 | deacetylase activity(GO:0019213) |
| 1.1 | 10.3 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 1.1 | 3.2 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 1.1 | 3.2 | GO:0036080 | GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080) |
| 1.1 | 7.4 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 1.1 | 4.2 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 1.1 | 3.2 | GO:0035173 | histone kinase activity(GO:0035173) |
| 1.1 | 5.3 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 1.0 | 3.1 | GO:0043035 | chromatin insulator sequence binding(GO:0043035) |
| 1.0 | 14.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 1.0 | 5.1 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 1.0 | 12.2 | GO:0070402 | NADPH binding(GO:0070402) |
| 1.0 | 3.0 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 1.0 | 18.8 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 1.0 | 1.9 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 1.0 | 1.9 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 0.9 | 5.6 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.9 | 2.8 | GO:0016823 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.9 | 2.8 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.9 | 2.8 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.9 | 1.9 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.9 | 1.9 | GO:0046979 | TAP2 binding(GO:0046979) |
| 0.9 | 3.7 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.9 | 30.9 | GO:0003774 | motor activity(GO:0003774) |
| 0.9 | 3.6 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.9 | 4.5 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.9 | 6.2 | GO:0005497 | androgen binding(GO:0005497) |
| 0.9 | 10.7 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.9 | 7.9 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 0.9 | 0.9 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 0.9 | 4.3 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.9 | 4.3 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.9 | 2.6 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 0.9 | 6.9 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.9 | 2.6 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.8 | 7.6 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.8 | 28.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.8 | 2.5 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 0.8 | 7.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.8 | 12.3 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.8 | 12.2 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.8 | 4.6 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.8 | 5.3 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.8 | 1.5 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 0.8 | 2.3 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.7 | 3.7 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.7 | 2.9 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.7 | 14.4 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.7 | 2.8 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.7 | 4.2 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.7 | 7.0 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.7 | 2.8 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.7 | 5.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.7 | 3.4 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.7 | 3.4 | GO:0052655 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.7 | 2.0 | GO:0004772 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 0.7 | 6.5 | GO:0043295 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.6 | 3.2 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.6 | 4.4 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 0.6 | 3.1 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.6 | 2.4 | GO:0047685 | amine sulfotransferase activity(GO:0047685) |
| 0.6 | 2.4 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.6 | 1.7 | GO:0050421 | oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
| 0.5 | 10.4 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.5 | 6.5 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.5 | 8.6 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.5 | 11.8 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.5 | 1.6 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.5 | 1.5 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.5 | 2.5 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.5 | 2.0 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.5 | 104.0 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.5 | 1.9 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.5 | 4.3 | GO:0004396 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.5 | 2.8 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.4 | 4.0 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.4 | 3.1 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.4 | 3.5 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.4 | 3.0 | GO:0016840 | carbon-nitrogen lyase activity(GO:0016840) |
| 0.4 | 1.3 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.4 | 0.4 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.4 | 18.3 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.4 | 4.7 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.4 | 2.9 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.4 | 0.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.4 | 1.2 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.4 | 19.2 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.4 | 2.7 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.4 | 1.1 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.4 | 6.0 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.4 | 1.5 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.4 | 6.6 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.4 | 0.4 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.4 | 7.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.4 | 2.9 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.4 | 1.8 | GO:0017161 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 0.3 | 23.6 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.3 | 41.0 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.3 | 1.0 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.3 | 1.6 | GO:0042979 | ornithine decarboxylase regulator activity(GO:0042979) |
| 0.3 | 1.9 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.3 | 6.7 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.3 | 4.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857) |
| 0.3 | 2.7 | GO:0055103 | ligase regulator activity(GO:0055103) |
| 0.3 | 0.9 | GO:0046577 | long-chain-alcohol oxidase activity(GO:0046577) |
| 0.3 | 6.0 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.3 | 6.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.3 | 1.4 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.3 | 1.9 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.3 | 6.6 | GO:0043236 | laminin binding(GO:0043236) |
| 0.3 | 1.1 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
| 0.3 | 4.7 | GO:0046961 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.3 | 0.8 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.2 | 1.2 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.2 | 2.6 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.2 | 1.4 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.2 | 0.7 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
| 0.2 | 3.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.2 | 19.3 | GO:0042393 | histone binding(GO:0042393) |
| 0.2 | 1.6 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.2 | 1.4 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.2 | 0.4 | GO:0004104 | cholinesterase activity(GO:0004104) |
| 0.2 | 5.4 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.2 | 0.8 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.2 | 1.1 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.2 | 0.6 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.2 | 1.4 | GO:0030884 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
| 0.2 | 0.5 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.2 | 1.4 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.2 | 0.9 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 0.9 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 2.2 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.1 | 1.0 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.1 | 17.5 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 1.5 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.1 | 0.4 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.1 | 3.0 | GO:0042805 | actinin binding(GO:0042805) |
| 0.1 | 1.5 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.1 | 3.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.1 | 3.2 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 0.4 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 1.4 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.1 | 0.3 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.1 | 0.8 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 0.3 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.1 | 0.3 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
| 0.1 | 0.8 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.1 | 1.8 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.1 | 2.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 1.0 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.1 | 0.4 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.1 | 3.3 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.1 | 0.2 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.1 | 0.3 | GO:0031779 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
| 0.1 | 0.4 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.0 | 1.0 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.4 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 0.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.1 | GO:0015556 | C4-dicarboxylate transmembrane transporter activity(GO:0015556) |
| 0.0 | 0.3 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 0.4 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.1 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.8 | 19.7 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 7.4 | 453.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 7.2 | 455.8 | PID ATR PATHWAY | ATR signaling pathway |
| 7.1 | 78.0 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 6.1 | 301.3 | PID PLK1 PATHWAY | PLK1 signaling events |
| 5.7 | 166.2 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 5.7 | 160.0 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 5.7 | 176.1 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 4.8 | 624.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 4.3 | 166.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 4.1 | 49.7 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 4.1 | 143.2 | PID BARD1 PATHWAY | BARD1 signaling events |
| 3.9 | 86.5 | PID ARF 3PATHWAY | Arf1 pathway |
| 3.7 | 185.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 3.5 | 70.5 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 3.4 | 94.6 | PID AURORA A PATHWAY | Aurora A signaling |
| 3.3 | 136.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 3.3 | 65.9 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 3.2 | 44.4 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 3.2 | 69.5 | PID ATM PATHWAY | ATM pathway |
| 2.6 | 174.4 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 2.6 | 80.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 2.5 | 116.1 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 2.4 | 155.7 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 2.3 | 9.1 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 2.3 | 68.0 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 2.2 | 60.9 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 2.1 | 10.6 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 2.1 | 77.8 | PID ALK1 PATHWAY | ALK1 signaling events |
| 2.0 | 51.1 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 2.0 | 26.2 | PID FOXO PATHWAY | FoxO family signaling |
| 1.9 | 71.3 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 1.9 | 15.3 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 1.9 | 45.3 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 1.7 | 133.3 | PID E2F PATHWAY | E2F transcription factor network |
| 1.6 | 40.6 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 1.6 | 102.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 1.4 | 71.1 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 1.3 | 8.1 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 1.3 | 30.4 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 1.3 | 74.3 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 1.2 | 74.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 1.2 | 46.4 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 1.1 | 22.5 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 1.1 | 53.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 1.1 | 31.1 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 1.1 | 44.5 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 1.1 | 55.0 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.9 | 21.2 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.9 | 21.0 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.9 | 34.8 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.9 | 94.9 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.8 | 54.2 | PID P73PATHWAY | p73 transcription factor network |
| 0.8 | 0.8 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.8 | 8.5 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.8 | 48.1 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.8 | 3.8 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.7 | 3.5 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.6 | 8.7 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.6 | 2.5 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.6 | 12.2 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.5 | 8.1 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.5 | 15.8 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.5 | 25.2 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.4 | 2.2 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.4 | 17.4 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.4 | 3.3 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.4 | 12.0 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.4 | 8.5 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.3 | 6.8 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.3 | 2.0 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.3 | 7.7 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.3 | 3.9 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.3 | 4.0 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.2 | 1.8 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.2 | 4.3 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.2 | 0.6 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.2 | 3.7 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 2.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 1.4 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.1 | 1.6 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 1.2 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.1 | 3.9 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.1 | 0.3 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.1 | 1.3 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.8 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 2.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.2 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 0.3 | PID IL1 PATHWAY | IL1-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 27.4 | 410.8 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 22.6 | 249.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 21.0 | 1446.7 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 19.2 | 441.4 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 18.9 | 341.0 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 16.4 | 82.1 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 15.8 | 63.1 | REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS | Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins |
| 14.6 | 43.9 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 14.2 | 1050.1 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 13.8 | 442.4 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 13.6 | 163.2 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 13.5 | 661.6 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 13.3 | 199.2 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 12.9 | 399.5 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 12.2 | 403.1 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 12.1 | 24.3 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 11.5 | 172.0 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 11.0 | 55.1 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 10.9 | 175.0 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 10.9 | 108.9 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 10.5 | 1366.3 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 9.7 | 271.5 | REACTOME KINESINS | Genes involved in Kinesins |
| 9.6 | 202.3 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 9.4 | 160.6 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 8.8 | 211.2 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 8.5 | 85.3 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 8.4 | 150.9 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 8.2 | 140.2 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 8.1 | 89.6 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 8.1 | 691.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 7.6 | 249.6 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 7.5 | 7.5 | REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
| 7.3 | 123.6 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 7.2 | 180.2 | REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX | Genes involved in Formation of RNA Pol II elongation complex |
| 7.0 | 408.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 7.0 | 805.4 | REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
| 6.5 | 116.4 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 6.3 | 100.7 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 6.3 | 106.8 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 5.9 | 81.9 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 5.8 | 35.1 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 5.7 | 79.9 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 5.7 | 51.3 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 5.6 | 78.8 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 5.4 | 141.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 5.3 | 21.2 | REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 |
| 5.1 | 10.1 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 5.0 | 84.2 | REACTOME GLOBAL GENOMIC NER GG NER | Genes involved in Global Genomic NER (GG-NER) |
| 4.9 | 225.1 | REACTOME TRANSLATION | Genes involved in Translation |
| 4.7 | 56.0 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 4.5 | 131.2 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 4.4 | 106.7 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 4.3 | 90.5 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 4.3 | 77.6 | REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
| 4.1 | 4.1 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 4.1 | 119.1 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 3.9 | 239.2 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 3.7 | 63.2 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 3.6 | 112.0 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 3.4 | 30.4 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 3.1 | 472.3 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 2.8 | 92.0 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 2.7 | 140.2 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 2.7 | 75.4 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 2.6 | 79.5 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 2.6 | 98.5 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 2.5 | 35.3 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 2.5 | 52.9 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 2.4 | 48.7 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 2.4 | 16.8 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 2.3 | 16.1 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 2.3 | 54.9 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 2.3 | 24.8 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 2.2 | 44.9 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 2.2 | 33.3 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 2.1 | 80.8 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 2.1 | 143.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 2.1 | 39.0 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 2.0 | 55.1 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 2.0 | 46.9 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 2.0 | 40.6 | REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| 2.0 | 83.2 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 1.8 | 52.2 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 1.8 | 53.4 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 1.7 | 6.9 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 1.7 | 38.7 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 1.6 | 29.5 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 1.6 | 24.5 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 1.6 | 12.7 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 1.6 | 55.0 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 1.6 | 31.4 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 1.5 | 18.5 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 1.5 | 12.2 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 1.5 | 22.4 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 1.5 | 20.3 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 1.4 | 41.0 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 1.4 | 25.8 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 1.3 | 26.4 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 1.3 | 44.8 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 1.3 | 23.1 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 1.3 | 9.0 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 1.2 | 8.7 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 1.2 | 44.6 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 1.2 | 17.6 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 1.1 | 13.7 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 1.1 | 27.4 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 1.1 | 7.5 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 1.1 | 110.7 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 1.0 | 4.0 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.9 | 7.5 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.9 | 3.7 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.9 | 44.6 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.9 | 3.6 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.9 | 80.0 | REACTOME APOPTOTIC EXECUTION PHASE | Genes involved in Apoptotic execution phase |
| 0.8 | 20.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.8 | 6.9 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.8 | 30.5 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.7 | 39.7 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.7 | 14.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.7 | 40.7 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.7 | 19.1 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.7 | 19.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.7 | 17.1 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.6 | 2.6 | REACTOME SIGNALING BY NOTCH3 | Genes involved in Signaling by NOTCH3 |
| 0.6 | 3.9 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.6 | 1.9 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.6 | 1.8 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 0.6 | 3.0 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.6 | 1.1 | REACTOME NUCLEOTIDE EXCISION REPAIR | Genes involved in Nucleotide Excision Repair |
| 0.5 | 7.7 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.5 | 15.2 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.5 | 4.1 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.5 | 15.8 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.5 | 12.4 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.5 | 2.4 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.5 | 12.5 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.5 | 5.5 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.5 | 2.3 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.4 | 4.8 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.4 | 18.5 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 0.4 | 1.1 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.3 | 1.3 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.3 | 6.7 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.3 | 3.8 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.3 | 6.4 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.3 | 7.9 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.2 | 16.5 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.2 | 3.6 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.2 | 1.7 | REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.2 | 5.9 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.2 | 1.0 | REACTOME CD28 CO STIMULATION | Genes involved in CD28 co-stimulation |
| 0.2 | 2.9 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.2 | 27.0 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |
| 0.2 | 1.8 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 4.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 15.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 5.1 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.1 | 0.9 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.1 | 0.7 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.1 | 1.6 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.1 | 1.7 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.1 | 0.1 | REACTOME BASE EXCISION REPAIR | Genes involved in Base Excision Repair |
| 0.1 | 0.3 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.1 | 1.1 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.5 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | Genes involved in Synthesis of bile acids and bile salts |
| 0.0 | 0.1 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.0 | 0.3 | REACTOME SIGNALING BY FGFR1 MUTANTS | Genes involved in Signaling by FGFR1 mutants |