Project
GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for ETS1
Z-value: 2.21
Motif logo
Transcription factors associated with ETS1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ETS1
|
ENSG00000134954.14 | ETS1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETS1 | hg38_v1_chr11_-_128522189_128522208 | 0.49 | 1.2e-14 | Click! |
Activity profile of ETS1 motif
Sorted Z-values of ETS1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ETS1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 29.1 | 87.3 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 23.4 | 70.2 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 23.2 | 69.6 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 15.1 | 45.2 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
| 14.4 | 57.6 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 13.4 | 13.4 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 12.5 | 12.5 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 12.4 | 49.7 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 11.4 | 22.8 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 11.3 | 79.2 | GO:1902915 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 11.0 | 44.1 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 10.9 | 43.7 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 10.9 | 32.7 | GO:1903595 | positive regulation of histamine secretion by mast cell(GO:1903595) |
| 10.9 | 32.6 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 10.8 | 54.1 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 10.3 | 31.0 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 9.7 | 58.1 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 9.4 | 28.1 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 9.1 | 36.6 | GO:0019860 | uracil metabolic process(GO:0019860) |
| 9.1 | 27.3 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 8.9 | 62.6 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 8.9 | 26.7 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547) |
| 8.8 | 43.9 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 8.6 | 51.6 | GO:0032079 | positive regulation of endodeoxyribonuclease activity(GO:0032079) |
| 8.2 | 41.1 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 8.1 | 24.4 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
| 8.0 | 40.1 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 8.0 | 63.8 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 7.5 | 30.0 | GO:0002357 | defense response to tumor cell(GO:0002357) |
| 7.4 | 51.5 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 6.9 | 6.9 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
| 6.9 | 27.5 | GO:0039507 | modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148) |
| 6.8 | 27.3 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 6.8 | 47.8 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 6.8 | 27.3 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 6.7 | 20.1 | GO:1903973 | negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) |
| 6.6 | 26.3 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 6.5 | 26.1 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 6.5 | 32.4 | GO:0070433 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) |
| 6.4 | 19.3 | GO:0070476 | peptidyl-glutamine methylation(GO:0018364) RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 6.4 | 102.5 | GO:0043248 | proteasome assembly(GO:0043248) |
| 6.4 | 44.5 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 6.3 | 113.9 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 6.3 | 25.1 | GO:0032072 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 6.3 | 25.0 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 6.1 | 49.0 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 6.1 | 18.4 | GO:0007174 | epidermal growth factor catabolic process(GO:0007174) |
| 6.1 | 24.5 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 6.1 | 54.7 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 5.9 | 59.1 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 5.8 | 122.8 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 5.8 | 23.3 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 5.8 | 11.6 | GO:0009826 | unidimensional cell growth(GO:0009826) |
| 5.6 | 73.4 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 5.6 | 16.8 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 5.6 | 27.8 | GO:0030242 | pexophagy(GO:0030242) |
| 5.5 | 49.9 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 5.4 | 49.0 | GO:0046070 | dGTP metabolic process(GO:0046070) |
| 5.4 | 10.9 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 5.4 | 16.2 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 5.4 | 21.4 | GO:0042247 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 5.3 | 5.3 | GO:1903094 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 5.3 | 78.9 | GO:1903297 | regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) |
| 5.1 | 35.8 | GO:0015866 | ADP transport(GO:0015866) |
| 5.1 | 5.1 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 4.9 | 78.7 | GO:0051014 | actin filament severing(GO:0051014) |
| 4.9 | 14.7 | GO:0002188 | translation reinitiation(GO:0002188) |
| 4.9 | 19.6 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
| 4.8 | 14.5 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 4.7 | 14.1 | GO:1903004 | regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006) |
| 4.7 | 14.1 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
| 4.7 | 23.5 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 4.6 | 18.6 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 4.6 | 23.1 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 4.6 | 13.7 | GO:1904732 | regulation of electron carrier activity(GO:1904732) |
| 4.6 | 36.4 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 4.5 | 31.4 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 4.4 | 61.8 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 4.3 | 13.0 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 4.3 | 17.2 | GO:0002441 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 4.3 | 25.5 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 4.2 | 16.9 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 4.2 | 12.6 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 4.1 | 37.0 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 4.1 | 28.6 | GO:0007144 | female meiosis I(GO:0007144) |
| 4.0 | 16.0 | GO:0043060 | meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 4.0 | 19.8 | GO:0034128 | detection of lipopolysaccharide(GO:0032497) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) |
| 4.0 | 15.8 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 3.9 | 11.8 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 3.9 | 15.6 | GO:0033625 | positive regulation of integrin activation(GO:0033625) |
| 3.9 | 15.4 | GO:0035261 | external genitalia morphogenesis(GO:0035261) |
| 3.8 | 15.4 | GO:0050917 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
| 3.8 | 22.9 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 3.7 | 11.2 | GO:0045799 | mRNA export from nucleus in response to heat stress(GO:0031990) positive regulation of chromatin assembly or disassembly(GO:0045799) |
| 3.7 | 15.0 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 3.7 | 81.6 | GO:0097320 | membrane tubulation(GO:0097320) |
| 3.6 | 14.6 | GO:0006235 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 3.6 | 25.3 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 3.6 | 28.8 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 3.6 | 10.8 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 3.5 | 7.1 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 3.5 | 63.1 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 3.5 | 10.5 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 3.5 | 13.8 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 3.4 | 13.7 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 3.4 | 10.1 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 3.3 | 63.4 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 3.3 | 26.1 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 3.2 | 13.0 | GO:1901873 | regulation of post-translational protein modification(GO:1901873) |
| 3.2 | 22.7 | GO:0032218 | riboflavin transport(GO:0032218) |
| 3.2 | 38.6 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
| 3.2 | 51.2 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 3.1 | 105.8 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 3.1 | 15.5 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 3.1 | 43.2 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 3.1 | 46.2 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 3.1 | 46.0 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 3.0 | 33.5 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 3.0 | 15.1 | GO:0071033 | nuclear retention of pre-mRNA at the site of transcription(GO:0071033) |
| 3.0 | 27.2 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 3.0 | 21.1 | GO:0007000 | nucleolus organization(GO:0007000) |
| 3.0 | 9.0 | GO:1901355 | response to rapamycin(GO:1901355) |
| 3.0 | 20.9 | GO:0008295 | spermine metabolic process(GO:0008215) spermidine biosynthetic process(GO:0008295) |
| 3.0 | 8.9 | GO:0043311 | positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
| 3.0 | 29.6 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 2.9 | 5.9 | GO:0035745 | T-helper 2 cell cytokine production(GO:0035745) |
| 2.9 | 8.8 | GO:0071226 | response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226) |
| 2.9 | 76.3 | GO:0097341 | inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) |
| 2.9 | 11.7 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 2.9 | 8.8 | GO:0045013 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 2.9 | 49.0 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 2.9 | 23.0 | GO:0039533 | regulation of MDA-5 signaling pathway(GO:0039533) |
| 2.8 | 22.8 | GO:0070235 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 2.8 | 8.5 | GO:0035927 | RNA import into mitochondrion(GO:0035927) |
| 2.8 | 33.8 | GO:0045651 | positive regulation of macrophage differentiation(GO:0045651) |
| 2.8 | 16.7 | GO:0097338 | response to clozapine(GO:0097338) |
| 2.8 | 8.4 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 2.8 | 44.2 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 2.7 | 32.6 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 2.7 | 10.9 | GO:2000630 | positive regulation of miRNA metabolic process(GO:2000630) |
| 2.7 | 10.8 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 2.7 | 45.7 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 2.6 | 108.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 2.6 | 116.1 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
| 2.6 | 94.6 | GO:0097421 | liver regeneration(GO:0097421) |
| 2.6 | 13.1 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 2.6 | 49.7 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 2.6 | 13.0 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 2.6 | 23.4 | GO:0048296 | isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 2.6 | 13.0 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 2.6 | 20.5 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 2.5 | 7.6 | GO:0014858 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle cell proliferation(GO:0014858) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
| 2.5 | 7.5 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 2.5 | 7.4 | GO:0060957 | endocardial cell fate commitment(GO:0060957) endocardial cushion cell differentiation(GO:0061443) endocardial cushion cell fate commitment(GO:0061445) |
| 2.5 | 7.4 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 2.5 | 31.9 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 2.4 | 7.2 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) |
| 2.4 | 37.6 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 2.3 | 4.7 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 2.3 | 20.9 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 2.3 | 32.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 2.3 | 111.3 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 2.3 | 16.1 | GO:0080009 | mRNA methylation(GO:0080009) |
| 2.3 | 6.9 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 2.3 | 6.9 | GO:0039689 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 2.2 | 11.1 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 2.2 | 6.7 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 2.2 | 4.4 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 2.2 | 87.8 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 2.1 | 17.0 | GO:0002353 | kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) |
| 2.1 | 2.1 | GO:0042223 | regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) |
| 2.1 | 65.4 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 2.1 | 6.3 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 2.1 | 6.3 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 2.0 | 8.2 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 2.0 | 44.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 2.0 | 49.6 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 2.0 | 176.3 | GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) |
| 2.0 | 63.4 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 2.0 | 7.9 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 2.0 | 11.8 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 1.9 | 38.6 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 1.9 | 240.8 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 1.9 | 5.8 | GO:1903939 | snoRNA localization(GO:0048254) negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
| 1.9 | 5.8 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 1.9 | 19.2 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 1.9 | 13.1 | GO:0051013 | microtubule severing(GO:0051013) |
| 1.9 | 7.5 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 1.8 | 16.6 | GO:0007549 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 1.8 | 42.5 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 1.8 | 14.7 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 1.8 | 18.2 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 1.8 | 3.5 | GO:0060528 | regulation of translational initiation by iron(GO:0006447) secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
| 1.8 | 15.9 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 1.8 | 61.3 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 1.7 | 24.4 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 1.7 | 62.1 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 1.7 | 8.6 | GO:1903232 | melanosome assembly(GO:1903232) |
| 1.7 | 11.9 | GO:0071569 | protein ufmylation(GO:0071569) |
| 1.7 | 8.5 | GO:0097240 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 1.7 | 13.5 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 1.7 | 10.1 | GO:0042695 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
| 1.7 | 20.2 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 1.7 | 5.0 | GO:1901895 | negative regulation of calcium-transporting ATPase activity(GO:1901895) |
| 1.6 | 11.4 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 1.6 | 11.3 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
| 1.6 | 23.9 | GO:0000338 | protein deneddylation(GO:0000338) |
| 1.6 | 48.1 | GO:0090383 | phagosome acidification(GO:0090383) |
| 1.5 | 18.5 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 1.5 | 70.4 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 1.5 | 19.8 | GO:0006983 | ER overload response(GO:0006983) |
| 1.5 | 33.4 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 1.5 | 9.0 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 1.5 | 85.8 | GO:0018279 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
| 1.5 | 18.0 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
| 1.5 | 1.5 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 1.5 | 4.5 | GO:0051182 | coenzyme transport(GO:0051182) |
| 1.5 | 40.4 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
| 1.5 | 4.5 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 1.5 | 1.5 | GO:0035711 | T-helper 1 cell activation(GO:0035711) |
| 1.4 | 36.1 | GO:0006144 | purine nucleobase metabolic process(GO:0006144) |
| 1.4 | 11.6 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 1.4 | 2.9 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
| 1.4 | 4.2 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 1.4 | 20.7 | GO:0071340 | skeletal muscle acetylcholine-gated channel clustering(GO:0071340) |
| 1.4 | 23.0 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 1.3 | 18.6 | GO:0006296 | nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) |
| 1.3 | 39.9 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 1.3 | 9.3 | GO:1903378 | positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 1.3 | 11.9 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 1.3 | 21.2 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 1.3 | 6.6 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 1.3 | 16.9 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 1.3 | 45.0 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 1.3 | 20.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 1.3 | 5.1 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 1.3 | 10.1 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 1.3 | 5.0 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 1.2 | 11.2 | GO:0009249 | protein lipoylation(GO:0009249) |
| 1.2 | 3.7 | GO:0045553 | TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556) |
| 1.2 | 3.6 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 1.2 | 4.8 | GO:0016240 | autophagosome docking(GO:0016240) |
| 1.2 | 4.8 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 1.2 | 7.1 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 1.2 | 10.6 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) positive regulation of viral entry into host cell(GO:0046598) |
| 1.2 | 2.4 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 1.2 | 11.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 1.2 | 13.8 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 1.1 | 19.5 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 1.1 | 10.3 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 1.1 | 4.5 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 1.1 | 15.9 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 1.1 | 7.9 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 1.1 | 11.2 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 1.1 | 37.9 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 1.1 | 10.0 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 1.1 | 13.2 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 1.1 | 8.8 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 1.1 | 31.7 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 1.1 | 4.4 | GO:0036229 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 1.1 | 3.3 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
| 1.1 | 5.4 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 1.1 | 6.5 | GO:0002857 | natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) |
| 1.1 | 18.1 | GO:0097345 | mitochondrial outer membrane permeabilization(GO:0097345) |
| 1.1 | 101.2 | GO:0006413 | translational initiation(GO:0006413) |
| 1.0 | 6.3 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 1.0 | 15.3 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) |
| 1.0 | 29.4 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 1.0 | 72.9 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 1.0 | 4.9 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 1.0 | 15.6 | GO:2001204 | regulation of osteoclast development(GO:2001204) |
| 1.0 | 7.8 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 1.0 | 9.7 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 1.0 | 8.7 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) establishment of protein localization to mitochondrial membrane(GO:0090151) |
| 1.0 | 7.7 | GO:0002759 | regulation of antimicrobial humoral response(GO:0002759) |
| 1.0 | 22.1 | GO:0035067 | negative regulation of histone acetylation(GO:0035067) |
| 1.0 | 21.0 | GO:0016246 | RNA interference(GO:0016246) |
| 1.0 | 19.1 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.9 | 8.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.9 | 24.7 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.9 | 5.3 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.9 | 12.4 | GO:0001783 | B cell apoptotic process(GO:0001783) |
| 0.9 | 194.3 | GO:0038093 | Fc receptor signaling pathway(GO:0038093) |
| 0.9 | 9.6 | GO:0034447 | very-low-density lipoprotein particle clearance(GO:0034447) |
| 0.9 | 18.1 | GO:0030220 | platelet formation(GO:0030220) |
| 0.9 | 2.6 | GO:0060335 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.8 | 8.4 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.8 | 32.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.8 | 6.7 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.8 | 10.8 | GO:0007143 | female meiotic division(GO:0007143) |
| 0.8 | 63.0 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.8 | 2.5 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.8 | 9.9 | GO:0002829 | negative regulation of type 2 immune response(GO:0002829) |
| 0.8 | 2.5 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.8 | 1.6 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.8 | 2.4 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
| 0.8 | 10.5 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.8 | 34.4 | GO:0002223 | innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
| 0.8 | 19.6 | GO:0050913 | sensory perception of bitter taste(GO:0050913) |
| 0.8 | 12.4 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.8 | 3.1 | GO:0033622 | integrin activation(GO:0033622) |
| 0.8 | 8.4 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.8 | 5.3 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.7 | 7.3 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.7 | 16.0 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.7 | 4.2 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.7 | 8.4 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.7 | 2.8 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.7 | 6.2 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 0.7 | 12.1 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
| 0.7 | 2.6 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 0.7 | 7.2 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.6 | 9.7 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.6 | 3.2 | GO:2000644 | regulation of receptor catabolic process(GO:2000644) |
| 0.6 | 8.3 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) |
| 0.6 | 1.9 | GO:0019087 | transformation of host cell by virus(GO:0019087) |
| 0.6 | 43.1 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.6 | 5.0 | GO:1902108 | regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108) |
| 0.6 | 12.5 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.6 | 27.0 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.6 | 41.4 | GO:0031398 | positive regulation of protein ubiquitination(GO:0031398) |
| 0.6 | 12.2 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.6 | 14.9 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.6 | 9.0 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.6 | 0.6 | GO:0001927 | exocyst assembly(GO:0001927) |
| 0.6 | 5.6 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.6 | 70.3 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.6 | 5.5 | GO:0071421 | manganese ion transmembrane transport(GO:0071421) |
| 0.5 | 14.6 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.5 | 10.7 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.5 | 12.3 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.5 | 4.8 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.5 | 11.6 | GO:0010259 | multicellular organism aging(GO:0010259) |
| 0.5 | 6.8 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.5 | 22.8 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.5 | 3.4 | GO:0002517 | T cell tolerance induction(GO:0002517) |
| 0.5 | 6.2 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.5 | 4.3 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 0.5 | 1.4 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
| 0.5 | 10.7 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
| 0.5 | 15.3 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.4 | 4.0 | GO:0032753 | positive regulation of interleukin-4 production(GO:0032753) |
| 0.4 | 1.3 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.4 | 21.1 | GO:0007566 | embryo implantation(GO:0007566) |
| 0.4 | 3.9 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.4 | 17.8 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.4 | 66.8 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.4 | 5.7 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.4 | 26.7 | GO:0048278 | vesicle docking(GO:0048278) |
| 0.4 | 2.8 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.4 | 7.7 | GO:0032480 | negative regulation of type I interferon production(GO:0032480) |
| 0.4 | 199.5 | GO:0002283 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
| 0.4 | 2.0 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 0.4 | 2.7 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.4 | 39.7 | GO:0006414 | translational elongation(GO:0006414) |
| 0.4 | 3.1 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.4 | 1.5 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.4 | 11.8 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.4 | 19.9 | GO:0042795 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.4 | 2.2 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.4 | 1.8 | GO:0046618 | drug export(GO:0046618) |
| 0.4 | 5.5 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.4 | 2.2 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.4 | 1.8 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.4 | 7.5 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.4 | 7.4 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.3 | 2.1 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.3 | 2.4 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.3 | 3.8 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.3 | 1.0 | GO:0090187 | positive regulation of pancreatic juice secretion(GO:0090187) |
| 0.3 | 79.0 | GO:0008380 | RNA splicing(GO:0008380) |
| 0.3 | 1.6 | GO:0001315 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 0.3 | 1.9 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.3 | 17.9 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.3 | 5.3 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.3 | 19.5 | GO:2000117 | negative regulation of cysteine-type endopeptidase activity(GO:2000117) |
| 0.3 | 16.7 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
| 0.3 | 17.1 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.3 | 5.5 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 0.3 | 13.3 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.3 | 5.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.2 | 10.0 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
| 0.2 | 1.0 | GO:0010310 | regulation of hydrogen peroxide metabolic process(GO:0010310) |
| 0.2 | 5.4 | GO:0050684 | regulation of mRNA processing(GO:0050684) |
| 0.2 | 4.6 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.2 | 0.7 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.2 | 9.4 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.2 | 8.9 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.2 | 1.7 | GO:0050858 | negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) |
| 0.2 | 9.2 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.2 | 0.2 | GO:0071609 | chemokine (C-C motif) ligand 5 production(GO:0071609) |
| 0.2 | 3.7 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.2 | 1.3 | GO:0003096 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
| 0.2 | 13.7 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.2 | 1.1 | GO:0018202 | peptidyl-histidine modification(GO:0018202) |
| 0.2 | 6.6 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.2 | 1.8 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.2 | 2.5 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.2 | 7.3 | GO:0090175 | Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175) |
| 0.1 | 0.1 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.1 | 4.2 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.1 | 0.8 | GO:0051665 | membrane raft localization(GO:0051665) |
| 0.1 | 1.0 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 1.0 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.1 | 0.4 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.1 | 3.3 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.1 | 0.7 | GO:0042791 | transcription initiation from RNA polymerase III promoter(GO:0006384) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.1 | 0.8 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
| 0.1 | 1.0 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
| 0.1 | 3.9 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.1 | 0.9 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.1 | 0.4 | GO:1903416 | response to glycoside(GO:1903416) |
| 0.1 | 1.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.1 | 0.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 0.4 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.7 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 0.2 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.0 | 1.1 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 1.0 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.5 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 0.2 | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
| 0.0 | 0.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.0 | 0.7 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 0.1 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 0.9 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 26.0 | 155.9 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
| 12.2 | 24.4 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 10.7 | 107.3 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 10.0 | 19.9 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 8.9 | 178.1 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 8.4 | 92.0 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 8.2 | 89.8 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 8.1 | 24.4 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 7.2 | 36.1 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 7.2 | 28.8 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 7.0 | 28.1 | GO:0071817 | MMXD complex(GO:0071817) |
| 6.8 | 27.3 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 6.8 | 20.4 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 6.8 | 54.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 6.8 | 81.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 6.8 | 74.6 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 6.5 | 116.8 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 6.3 | 56.3 | GO:0032010 | phagolysosome(GO:0032010) |
| 6.2 | 18.6 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 6.1 | 18.4 | GO:0032419 | extrinsic component of lysosome membrane(GO:0032419) |
| 6.0 | 18.1 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 5.9 | 47.4 | GO:0072487 | MSL complex(GO:0072487) |
| 5.8 | 75.9 | GO:0005688 | U6 snRNP(GO:0005688) |
| 5.7 | 45.7 | GO:0070522 | nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522) |
| 5.7 | 28.5 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 5.6 | 90.0 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 5.5 | 16.5 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 5.3 | 47.4 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 5.2 | 20.6 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 5.1 | 15.4 | GO:0032116 | SMC loading complex(GO:0032116) |
| 5.1 | 35.9 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 4.9 | 4.9 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 4.8 | 14.5 | GO:0008623 | CHRAC(GO:0008623) |
| 4.8 | 61.8 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 4.7 | 23.5 | GO:0097422 | tubular endosome(GO:0097422) |
| 4.4 | 8.8 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 4.3 | 21.7 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 4.3 | 86.1 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 4.3 | 111.7 | GO:0001891 | phagocytic cup(GO:0001891) |
| 4.3 | 55.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 4.3 | 21.4 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 4.2 | 29.1 | GO:0032021 | NELF complex(GO:0032021) |
| 4.1 | 16.3 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 4.0 | 16.0 | GO:0005715 | late recombination nodule(GO:0005715) |
| 3.9 | 35.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 3.9 | 19.4 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 3.8 | 23.1 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 3.8 | 15.3 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 3.8 | 30.5 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 3.8 | 7.5 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 3.7 | 18.6 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 3.7 | 11.1 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 3.6 | 71.9 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 3.5 | 378.6 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 3.5 | 10.6 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 3.5 | 10.5 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 3.4 | 74.2 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 3.4 | 10.1 | GO:0097441 | basilar dendrite(GO:0097441) |
| 3.3 | 30.0 | GO:0044194 | cytolytic granule(GO:0044194) |
| 3.2 | 26.0 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 3.2 | 16.2 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 3.2 | 58.1 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 3.2 | 16.1 | GO:0045293 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 3.2 | 181.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 3.2 | 12.7 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 3.1 | 15.6 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 3.1 | 15.5 | GO:0036398 | TCR signalosome(GO:0036398) |
| 2.9 | 35.3 | GO:0030008 | TRAPP complex(GO:0030008) |
| 2.8 | 28.2 | GO:0097255 | R2TP complex(GO:0097255) |
| 2.8 | 25.0 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 2.7 | 41.2 | GO:0032059 | bleb(GO:0032059) |
| 2.7 | 43.9 | GO:0033179 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 2.7 | 8.2 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 2.7 | 24.5 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 2.7 | 8.1 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 2.7 | 13.4 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 2.7 | 98.3 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 2.7 | 45.1 | GO:0032433 | filopodium tip(GO:0032433) |
| 2.6 | 28.9 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 2.6 | 52.1 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 2.6 | 23.2 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 2.6 | 10.3 | GO:0000346 | transcription export complex(GO:0000346) |
| 2.5 | 15.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 2.5 | 19.9 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 2.4 | 80.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 2.4 | 24.0 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 2.4 | 21.5 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 2.4 | 19.1 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 2.2 | 49.0 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 2.2 | 10.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 2.1 | 23.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 2.0 | 40.6 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 2.0 | 10.1 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 2.0 | 14.1 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 1.9 | 28.8 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 1.9 | 19.0 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 1.9 | 238.7 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 1.9 | 11.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 1.9 | 7.4 | GO:0048179 | activin receptor complex(GO:0048179) |
| 1.9 | 7.4 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 1.8 | 12.9 | GO:0031415 | NatA complex(GO:0031415) |
| 1.8 | 114.8 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 1.7 | 35.0 | GO:0005686 | U2 snRNP(GO:0005686) |
| 1.7 | 12.2 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 1.7 | 8.6 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 1.7 | 6.8 | GO:0070876 | SOSS complex(GO:0070876) |
| 1.7 | 5.1 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 1.7 | 23.2 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 1.6 | 23.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 1.5 | 30.8 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 1.5 | 7.7 | GO:0032044 | DSIF complex(GO:0032044) |
| 1.5 | 6.2 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 1.5 | 14.6 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 1.4 | 32.4 | GO:0030056 | hemidesmosome(GO:0030056) |
| 1.4 | 8.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 1.3 | 10.7 | GO:0034709 | methylosome(GO:0034709) |
| 1.3 | 27.5 | GO:0097342 | CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342) |
| 1.3 | 14.1 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 1.2 | 27.2 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 1.2 | 2.5 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 1.2 | 67.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 1.2 | 15.6 | GO:0042555 | MCM complex(GO:0042555) |
| 1.2 | 29.7 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 1.2 | 13.0 | GO:0030870 | Mre11 complex(GO:0030870) |
| 1.2 | 3.5 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 1.2 | 10.5 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 1.1 | 8.9 | GO:0043219 | lateral loop(GO:0043219) |
| 1.1 | 5.6 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 1.1 | 75.0 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 1.1 | 16.5 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 1.1 | 6.5 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 1.1 | 10.9 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 1.1 | 132.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 1.1 | 73.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 1.1 | 2.1 | GO:0055087 | Ski complex(GO:0055087) |
| 1.1 | 39.3 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 1.1 | 13.8 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 1.0 | 45.0 | GO:0031201 | SNARE complex(GO:0031201) |
| 1.0 | 16.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 1.0 | 30.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 1.0 | 16.1 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 1.0 | 8.6 | GO:0042382 | paraspeckles(GO:0042382) |
| 1.0 | 4.8 | GO:0044308 | axonal spine(GO:0044308) |
| 0.9 | 5.7 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.9 | 21.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.9 | 13.0 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.9 | 11.9 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.9 | 35.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.9 | 5.3 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.9 | 402.2 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.9 | 14.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.9 | 9.4 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.8 | 10.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.8 | 2.5 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.8 | 11.8 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.8 | 120.9 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.8 | 12.7 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.8 | 7.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.8 | 18.7 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.8 | 4.6 | GO:0005684 | U2-type spliceosomal complex(GO:0005684) |
| 0.8 | 13.0 | GO:0030904 | retromer complex(GO:0030904) |
| 0.8 | 6.8 | GO:0071203 | WASH complex(GO:0071203) |
| 0.7 | 4.5 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.7 | 10.3 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.7 | 8.8 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.7 | 2.2 | GO:0000818 | nuclear MIS12/MIND complex(GO:0000818) |
| 0.7 | 68.7 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.7 | 18.2 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.7 | 6.8 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.7 | 14.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.7 | 7.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.7 | 13.0 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.6 | 8.4 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.6 | 1.9 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.6 | 10.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.6 | 33.9 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.6 | 35.4 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.6 | 30.7 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.6 | 24.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.6 | 5.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.5 | 2.7 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.5 | 6.5 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.5 | 5.8 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.5 | 20.5 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.5 | 6.7 | GO:0097433 | dense body(GO:0097433) |
| 0.5 | 15.8 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.5 | 37.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.5 | 79.2 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.5 | 71.2 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.5 | 33.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.5 | 30.2 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.5 | 5.0 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.4 | 4.0 | GO:0032039 | integrator complex(GO:0032039) |
| 0.4 | 12.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.4 | 4.5 | GO:0070449 | elongin complex(GO:0070449) |
| 0.4 | 4.9 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.4 | 4.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.4 | 1.1 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.3 | 43.9 | GO:0005884 | actin filament(GO:0005884) |
| 0.3 | 15.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.3 | 7.5 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.3 | 65.4 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.3 | 9.4 | GO:0032420 | stereocilium(GO:0032420) |
| 0.3 | 23.5 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.3 | 1.6 | GO:0032009 | early phagosome(GO:0032009) |
| 0.3 | 47.4 | GO:0043197 | dendritic spine(GO:0043197) neuron spine(GO:0044309) |
| 0.3 | 14.3 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.3 | 1.8 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.3 | 2.7 | GO:0045495 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.3 | 5.4 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.3 | 1.1 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.3 | 1.4 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.3 | 0.8 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.2 | 2.5 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.2 | 1.0 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.2 | 21.5 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.2 | 6.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.2 | 1.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.2 | 2.8 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.2 | 2.2 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.2 | 3.4 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.2 | 9.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.2 | 4.2 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.2 | 2.6 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 0.9 | GO:0097450 | astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451) |
| 0.1 | 1.3 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.1 | 6.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 16.7 | GO:0000922 | spindle pole(GO:0000922) |
| 0.1 | 8.6 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.1 | 11.5 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 0.4 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.1 | 32.2 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.1 | 10.7 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 9.0 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 0.7 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.1 | 2.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 3.4 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.1 | 2.9 | GO:0005840 | ribosome(GO:0005840) |
| 0.1 | 2.2 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 0.3 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 0.2 | GO:0000145 | exocyst(GO:0000145) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 23.4 | 70.2 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 22.3 | 155.9 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 11.2 | 55.9 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 11.0 | 44.1 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 10.9 | 32.7 | GO:0044713 | GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693) |
| 10.5 | 42.0 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 10.0 | 50.2 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 9.9 | 29.7 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 9.1 | 99.8 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) |
| 9.0 | 81.3 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 9.0 | 54.1 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 8.5 | 25.6 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 8.2 | 49.0 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 7.9 | 31.4 | GO:0019976 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
| 7.5 | 29.9 | GO:0015207 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 7.2 | 36.1 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 7.2 | 28.8 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 7.0 | 56.3 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 6.8 | 27.3 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 6.8 | 54.2 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 6.4 | 44.9 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 6.3 | 25.1 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 6.0 | 59.6 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 5.8 | 23.3 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 5.8 | 17.4 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 5.7 | 34.3 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 5.7 | 45.7 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 5.6 | 90.0 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 5.6 | 16.7 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 5.3 | 94.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 4.9 | 83.8 | GO:0043495 | protein anchor(GO:0043495) |
| 4.9 | 14.7 | GO:0055100 | adiponectin binding(GO:0055100) |
| 4.8 | 14.4 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 4.6 | 92.7 | GO:0005522 | profilin binding(GO:0005522) |
| 4.6 | 18.5 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 4.6 | 13.8 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 4.6 | 27.5 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 4.5 | 9.0 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 4.5 | 49.7 | GO:0004673 | protein histidine kinase activity(GO:0004673) |
| 4.5 | 58.3 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 4.4 | 113.9 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 4.2 | 25.3 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
| 4.2 | 12.7 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 4.2 | 20.9 | GO:0038051 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 4.2 | 24.9 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 4.1 | 24.5 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 4.0 | 56.2 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 3.9 | 23.2 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 3.8 | 15.4 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 3.8 | 7.7 | GO:0051717 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) |
| 3.8 | 45.7 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 3.7 | 7.5 | GO:0032558 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 3.7 | 11.1 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 3.7 | 40.4 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 3.5 | 24.8 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 3.5 | 45.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 3.5 | 24.6 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 3.5 | 10.4 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 3.4 | 10.1 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 3.3 | 23.1 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 3.2 | 13.0 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 3.2 | 22.7 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 3.1 | 37.1 | GO:0015266 | protein channel activity(GO:0015266) |
| 3.1 | 9.2 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 3.0 | 18.3 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 3.0 | 114.2 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 3.0 | 24.0 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 2.9 | 8.6 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 2.8 | 45.2 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 2.8 | 16.9 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 2.8 | 58.7 | GO:0000339 | RNA cap binding(GO:0000339) |
| 2.7 | 54.9 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 2.7 | 127.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 2.6 | 67.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 2.6 | 15.4 | GO:0036033 | mediator complex binding(GO:0036033) |
| 2.6 | 18.0 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 2.6 | 20.5 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 2.5 | 22.8 | GO:0043426 | MRF binding(GO:0043426) |
| 2.5 | 49.6 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 2.5 | 7.4 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 2.5 | 27.0 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 2.4 | 92.8 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 2.4 | 21.5 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 2.4 | 23.9 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 2.4 | 14.1 | GO:0016748 | succinyltransferase activity(GO:0016748) |
| 2.3 | 7.0 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 2.3 | 27.8 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 2.3 | 16.2 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 2.3 | 15.9 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 2.3 | 15.9 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 2.2 | 8.9 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 2.2 | 6.7 | GO:0098918 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 2.2 | 17.5 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 2.2 | 136.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 2.2 | 10.9 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 2.1 | 6.4 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 2.1 | 10.6 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 2.1 | 31.8 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 2.1 | 12.7 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 2.1 | 6.3 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 2.1 | 90.5 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 2.0 | 26.2 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 2.0 | 64.0 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 2.0 | 5.9 | GO:0005347 | adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217) |
| 2.0 | 5.9 | GO:0004618 | copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682) |
| 2.0 | 7.8 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 1.9 | 9.7 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 1.9 | 387.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.9 | 38.6 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 1.9 | 9.6 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 1.9 | 5.6 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 1.9 | 13.1 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 1.9 | 48.1 | GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 1.8 | 14.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 1.8 | 9.0 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 1.8 | 32.4 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 1.8 | 16.1 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 1.8 | 41.0 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 1.8 | 12.4 | GO:0043274 | phospholipase binding(GO:0043274) |
| 1.8 | 15.9 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 1.7 | 6.8 | GO:0008135 | translation factor activity, RNA binding(GO:0008135) |
| 1.7 | 37.1 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 1.7 | 23.6 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 1.7 | 23.6 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 1.7 | 10.1 | GO:0089720 | caspase binding(GO:0089720) |
| 1.7 | 6.7 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 1.6 | 4.8 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 1.6 | 36.8 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 1.6 | 22.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 1.6 | 10.9 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 1.6 | 25.0 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 1.5 | 7.7 | GO:0016531 | metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531) |
| 1.5 | 9.3 | GO:0070990 | snRNP binding(GO:0070990) |
| 1.5 | 16.9 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 1.5 | 23.0 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 1.5 | 32.0 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 1.5 | 36.2 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 1.5 | 6.0 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 1.5 | 10.4 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
| 1.5 | 20.5 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 1.5 | 14.6 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 1.4 | 27.0 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 1.4 | 36.7 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 1.4 | 8.4 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 1.4 | 8.4 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 1.4 | 26.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 1.4 | 6.9 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 1.4 | 28.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 1.4 | 18.9 | GO:0031386 | protein tag(GO:0031386) |
| 1.3 | 6.7 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 1.3 | 4.0 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 1.3 | 16.0 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 1.3 | 22.5 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 1.3 | 33.0 | GO:0031489 | myosin V binding(GO:0031489) |
| 1.3 | 36.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 1.3 | 13.0 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 1.2 | 24.9 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 1.2 | 23.5 | GO:0098847 | sequence-specific single stranded DNA binding(GO:0098847) |
| 1.2 | 54.0 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 1.2 | 37.9 | GO:0030228 | lipoprotein particle receptor activity(GO:0030228) |
| 1.2 | 30.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 1.2 | 8.4 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 1.2 | 71.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 1.2 | 35.4 | GO:0008143 | poly(A) binding(GO:0008143) |
| 1.2 | 15.3 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 1.2 | 3.5 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
| 1.2 | 5.8 | GO:0016936 | galactoside binding(GO:0016936) |
| 1.1 | 17.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 1.1 | 6.7 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 1.1 | 7.6 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 1.1 | 66.6 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 1.1 | 18.3 | GO:0016502 | purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) |
| 1.1 | 36.0 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 1.1 | 4.2 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 1.1 | 10.5 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 1.0 | 19.5 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 1.0 | 11.3 | GO:0033691 | sialic acid binding(GO:0033691) |
| 1.0 | 12.5 | GO:0046790 | virion binding(GO:0046790) |
| 1.0 | 16.2 | GO:0051400 | BH domain binding(GO:0051400) |
| 1.0 | 97.9 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.9 | 8.5 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.9 | 217.2 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.9 | 11.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.9 | 13.3 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.9 | 3.5 | GO:0044323 | 9-cis retinoic acid receptor activity(GO:0004886) retinoic acid-responsive element binding(GO:0044323) vitamin D response element binding(GO:0070644) |
| 0.8 | 4.2 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 0.8 | 12.5 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.8 | 43.3 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.8 | 34.1 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.8 | 23.2 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.8 | 8.3 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.8 | 2.5 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.8 | 49.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.8 | 5.7 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.8 | 12.1 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.8 | 5.7 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.8 | 33.1 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.8 | 3.2 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.8 | 17.2 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.8 | 47.6 | GO:0019003 | GDP binding(GO:0019003) |
| 0.8 | 12.2 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.8 | 15.3 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.7 | 37.8 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.7 | 3.0 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.7 | 24.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.7 | 14.6 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.7 | 32.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.7 | 13.7 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.7 | 17.2 | GO:0022829 | wide pore channel activity(GO:0022829) |
| 0.7 | 33.9 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.7 | 1.4 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.7 | 12.4 | GO:0051430 | mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.7 | 38.0 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.7 | 4.1 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.7 | 8.5 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.7 | 6.5 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.6 | 28.3 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.6 | 18.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.6 | 1.9 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.6 | 14.0 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.6 | 5.0 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.6 | 15.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.6 | 5.5 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 0.6 | 26.4 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.6 | 9.1 | GO:0005521 | lamin binding(GO:0005521) |
| 0.6 | 2.4 | GO:0061513 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 0.6 | 5.2 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.6 | 11.9 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.6 | 10.7 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.6 | 2.2 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.6 | 12.7 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
| 0.6 | 12.1 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.5 | 2.7 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.5 | 2.1 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.5 | 4.7 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.5 | 4.1 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.5 | 19.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.5 | 16.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.5 | 1.0 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.5 | 6.9 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.5 | 5.8 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.5 | 4.8 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.5 | 2.8 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.5 | 14.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.5 | 13.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.5 | 1.8 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.5 | 2.3 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.5 | 36.5 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.4 | 12.1 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.4 | 7.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.4 | 6.2 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.4 | 2.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 0.4 | 12.2 | GO:0071949 | FAD binding(GO:0071949) |
| 0.4 | 4.8 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.4 | 0.4 | GO:0008413 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539) |
| 0.4 | 25.9 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.4 | 12.4 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.4 | 11.4 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.4 | 16.1 | GO:0042805 | actinin binding(GO:0042805) |
| 0.4 | 1.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.4 | 1.1 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.4 | 5.4 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.4 | 5.0 | GO:0010857 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857) |
| 0.4 | 1.1 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.4 | 3.9 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.4 | 1.4 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.4 | 42.5 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.3 | 48.3 | GO:0005178 | integrin binding(GO:0005178) |
| 0.3 | 3.1 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.3 | 0.7 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 0.3 | 13.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.3 | 6.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.3 | 7.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.3 | 7.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.3 | 63.6 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.3 | 20.0 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.3 | 6.5 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.3 | 36.3 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.3 | 14.6 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.3 | 16.4 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.3 | 1.2 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.3 | 26.8 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.3 | 8.0 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.3 | 1.1 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.3 | 1.4 | GO:0001164 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.3 | 7.6 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.3 | 4.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.3 | 1.0 | GO:0034191 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) apolipoprotein A-I receptor binding(GO:0034191) |
| 0.3 | 2.3 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.2 | 3.5 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.2 | 5.5 | GO:0043236 | laminin binding(GO:0043236) |
| 0.2 | 9.6 | GO:1990782 | protein tyrosine kinase binding(GO:1990782) |
| 0.2 | 1.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.2 | 2.9 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.2 | 1.6 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.2 | 6.2 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.2 | 5.9 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.2 | 1.0 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.2 | 7.4 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.2 | 3.5 | GO:0005537 | mannose binding(GO:0005537) |
| 0.2 | 0.5 | GO:0003696 | satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237) |
| 0.2 | 2.0 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.1 | 9.9 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.1 | 22.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.1 | 3.4 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.1 | 5.0 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 2.0 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.1 | 1.8 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.1 | 12.5 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.1 | 0.4 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
| 0.1 | 13.2 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.1 | 0.5 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.1 | 4.9 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.1 | 0.7 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.1 | 6.4 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 1.4 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.1 | 1.0 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 7.0 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.1 | 2.3 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 19.9 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 0.5 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.1 | 0.2 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.1 | 0.3 | GO:0047238 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) |
| 0.0 | 3.1 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.4 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 1.5 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.0 | 0.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.7 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.3 | 17.2 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 4.3 | 208.4 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 4.2 | 362.6 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 4.0 | 167.1 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 3.5 | 328.3 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 3.4 | 80.5 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 3.1 | 24.4 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 2.9 | 41.2 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 2.7 | 217.6 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 2.5 | 9.9 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 1.5 | 32.1 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 1.5 | 141.2 | PID NOTCH PATHWAY | Notch signaling pathway |
| 1.4 | 31.8 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 1.4 | 27.2 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 1.3 | 41.0 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 1.3 | 44.3 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 1.2 | 45.7 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 1.1 | 16.7 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 1.1 | 131.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 1.1 | 75.6 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 1.1 | 61.1 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 1.0 | 5.2 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 1.0 | 54.1 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 1.0 | 23.6 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 1.0 | 42.0 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 1.0 | 30.5 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 1.0 | 34.8 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.8 | 24.3 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.8 | 37.5 | PID ATR PATHWAY | ATR signaling pathway |
| 0.7 | 34.6 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.6 | 16.2 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.6 | 25.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.6 | 42.8 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.6 | 15.9 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.6 | 10.0 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.6 | 13.5 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.6 | 41.1 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.6 | 13.0 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.6 | 3.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.6 | 7.8 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.5 | 20.8 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.5 | 3.6 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.5 | 8.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.4 | 17.8 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.4 | 28.2 | PID E2F PATHWAY | E2F transcription factor network |
| 0.4 | 7.4 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.4 | 12.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.4 | 14.0 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.3 | 8.9 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.3 | 6.8 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.3 | 11.8 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.3 | 3.1 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.3 | 5.7 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.3 | 5.0 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.3 | 4.7 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.3 | 7.5 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.2 | 9.1 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.2 | 17.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.2 | 7.0 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.2 | 6.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.2 | 22.1 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.2 | 5.6 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 6.7 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 6.9 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 4.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 1.7 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 1.0 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 1.3 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 2.2 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.1 | 0.2 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 1.5 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.7 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.1 | PID ERBB4 PATHWAY | ErbB4 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.1 | 169.5 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 5.8 | 29.0 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
| 5.5 | 65.5 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 4.5 | 57.9 | REACTOME SIGNALING BY NOTCH3 | Genes involved in Signaling by NOTCH3 |
| 4.1 | 57.7 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 4.1 | 85.5 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 3.7 | 70.0 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 3.7 | 124.5 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 3.6 | 271.2 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 3.5 | 186.3 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 3.5 | 62.6 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 3.2 | 419.0 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 3.1 | 40.6 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 3.1 | 205.9 | REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
| 3.0 | 132.6 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 3.0 | 65.7 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 2.7 | 253.6 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 2.7 | 24.0 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 2.5 | 37.9 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 2.3 | 9.4 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 2.3 | 27.3 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 2.2 | 49.1 | REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
| 2.2 | 73.5 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 2.2 | 52.0 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 2.1 | 41.3 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 2.1 | 135.8 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 2.0 | 32.8 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 2.0 | 88.0 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 1.9 | 61.8 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 1.9 | 11.5 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 1.9 | 57.7 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 1.9 | 39.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 1.9 | 26.0 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 1.8 | 29.6 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 1.8 | 27.5 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 1.8 | 16.3 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 1.8 | 32.1 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 1.8 | 19.6 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 1.8 | 40.8 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 1.7 | 47.1 | REACTOME TRANSLATION | Genes involved in Translation |
| 1.7 | 29.5 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 1.7 | 15.4 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 1.7 | 34.0 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 1.7 | 111.7 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 1.6 | 61.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 1.6 | 174.0 | REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
| 1.4 | 19.9 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 1.4 | 44.7 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 1.3 | 16.2 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 1.3 | 9.2 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 1.3 | 21.9 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 1.3 | 60.1 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 1.2 | 17.3 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 1.2 | 30.8 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 1.2 | 8.4 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 1.2 | 15.6 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 1.2 | 35.4 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 1.2 | 29.1 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 1.1 | 22.6 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 1.1 | 50.5 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 1.1 | 25.3 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 1.1 | 19.7 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 1.1 | 37.4 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 1.0 | 20.9 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 1.0 | 83.4 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.9 | 7.6 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.9 | 27.1 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.9 | 3.6 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.9 | 21.8 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.9 | 5.2 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.8 | 45.9 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.8 | 19.4 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.8 | 23.1 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.8 | 16.7 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.8 | 15.3 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.7 | 11.2 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.7 | 11.9 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.7 | 110.9 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.7 | 14.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.7 | 8.8 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.7 | 25.3 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.7 | 56.6 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
| 0.6 | 15.2 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.6 | 19.4 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.6 | 6.7 | REACTOME TCR SIGNALING | Genes involved in TCR signaling |
| 0.5 | 15.3 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.5 | 10.5 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.5 | 10.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.5 | 24.6 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.4 | 32.0 | REACTOME APOPTOTIC EXECUTION PHASE | Genes involved in Apoptotic execution phase |
| 0.4 | 18.3 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.4 | 4.8 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.3 | 9.0 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.3 | 15.2 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.3 | 3.1 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.3 | 4.7 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.2 | 30.4 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.2 | 1.4 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.2 | 9.9 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.2 | 1.3 | REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 0.2 | 3.2 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.2 | 4.0 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.2 | 6.4 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.2 | 1.4 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.2 | 1.3 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.2 | 3.2 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 1.6 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 2.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 0.6 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 5.7 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 1.8 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 1.8 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 0.7 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 1.9 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 1.6 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 1.3 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.2 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.0 | 0.9 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.0 | 1.5 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.4 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.0 | 1.0 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |