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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for ETV1_ERF_FEV_ELF1
Z-value: 2.04
Motif logo
Transcription factors associated with ETV1_ERF_FEV_ELF1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ETV1
|
ENSG00000006468.14 | ETV1 |
|
ERF
|
ENSG00000105722.10 | ERF |
|
FEV
|
ENSG00000163497.3 | FEV |
|
ELF1
|
ENSG00000120690.16 | ELF1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ELF1 | hg38_v1_chr13_-_41019289_41019343 | -0.71 | 2.7e-35 | Click! |
| ERF | hg38_v1_chr19_-_42255119_42255137 | 0.26 | 7.6e-05 | Click! |
| ETV1 | hg38_v1_chr7_-_13988863_13988891 | 0.21 | 2.0e-03 | Click! |
| FEV | hg38_v1_chr2_-_218985176_218985205 | -0.01 | 8.6e-01 | Click! |
Activity profile of ETV1_ERF_FEV_ELF1 motif
Sorted Z-values of ETV1_ERF_FEV_ELF1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ETV1_ERF_FEV_ELF1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 16.9 | 84.7 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 16.9 | 84.5 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 15.4 | 15.4 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
| 15.2 | 45.5 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 14.2 | 42.7 | GO:0035048 | splicing factor protein import into nucleus(GO:0035048) |
| 14.1 | 84.4 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 13.4 | 40.2 | GO:0070650 | endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650) |
| 12.8 | 38.3 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
| 11.8 | 35.3 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) |
| 10.2 | 50.8 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 10.0 | 30.1 | GO:0018283 | metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283) |
| 10.0 | 30.1 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 9.5 | 28.6 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
| 9.2 | 27.7 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 8.4 | 25.2 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 8.0 | 32.1 | GO:0021539 | subthalamus development(GO:0021539) |
| 7.8 | 62.2 | GO:0007144 | female meiosis I(GO:0007144) |
| 7.7 | 23.2 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 7.7 | 30.6 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 7.6 | 38.1 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 7.5 | 22.6 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 7.4 | 37.2 | GO:1904579 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
| 7.4 | 36.9 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 7.1 | 35.7 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 7.1 | 21.2 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 6.9 | 34.3 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 6.8 | 20.3 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 6.7 | 26.7 | GO:0046203 | spermidine catabolic process(GO:0046203) |
| 6.3 | 94.6 | GO:0000338 | protein deneddylation(GO:0000338) |
| 6.3 | 31.5 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 6.3 | 31.3 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 6.2 | 18.7 | GO:2000397 | ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 6.0 | 18.1 | GO:0043321 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 6.0 | 18.0 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 5.9 | 17.8 | GO:1904732 | regulation of electron carrier activity(GO:1904732) |
| 5.9 | 23.7 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 5.7 | 28.5 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 5.6 | 16.8 | GO:0002905 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 5.5 | 22.1 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 5.4 | 37.8 | GO:0032218 | riboflavin transport(GO:0032218) |
| 5.4 | 16.2 | GO:2000097 | chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 5.4 | 21.5 | GO:2000232 | regulation of rRNA processing(GO:2000232) |
| 5.4 | 43.0 | GO:0046061 | dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061) |
| 5.2 | 15.7 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 5.1 | 35.6 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 5.0 | 15.1 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 4.8 | 19.2 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 4.7 | 47.4 | GO:0045176 | apical protein localization(GO:0045176) |
| 4.7 | 37.8 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 4.6 | 91.5 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 4.5 | 13.6 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 4.5 | 22.6 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 4.5 | 49.7 | GO:1904896 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 4.4 | 17.8 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 4.4 | 26.5 | GO:0051030 | snRNA transport(GO:0051030) |
| 4.4 | 22.1 | GO:0090034 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
| 4.4 | 13.1 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 4.4 | 8.7 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 4.4 | 17.5 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 4.4 | 21.8 | GO:0019323 | pentose catabolic process(GO:0019323) |
| 4.3 | 73.6 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 4.3 | 12.8 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
| 4.2 | 84.2 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 4.2 | 63.1 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 4.2 | 88.1 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 4.0 | 64.8 | GO:0043248 | proteasome assembly(GO:0043248) |
| 3.9 | 35.2 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 3.9 | 296.4 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 3.9 | 11.6 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 3.9 | 34.8 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 3.9 | 11.6 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 3.8 | 22.8 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 3.8 | 30.3 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 3.8 | 30.2 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 3.7 | 11.0 | GO:2000847 | negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 3.6 | 25.3 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 3.6 | 21.7 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 3.6 | 39.6 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 3.6 | 106.7 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 3.6 | 10.7 | GO:0007174 | epidermal growth factor catabolic process(GO:0007174) |
| 3.5 | 14.2 | GO:0051182 | coenzyme transport(GO:0051182) |
| 3.4 | 10.3 | GO:0060296 | regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 3.4 | 30.7 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 3.4 | 53.9 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 3.4 | 53.6 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 3.3 | 76.3 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 3.3 | 9.9 | GO:0001188 | RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189) |
| 3.2 | 29.1 | GO:2000580 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 3.2 | 51.4 | GO:0045116 | protein neddylation(GO:0045116) |
| 3.2 | 51.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 3.2 | 47.3 | GO:0006983 | ER overload response(GO:0006983) |
| 3.1 | 15.4 | GO:2000645 | negative regulation of receptor catabolic process(GO:2000645) |
| 3.0 | 36.3 | GO:1904869 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 3.0 | 18.1 | GO:1901896 | positive regulation of calcium-transporting ATPase activity(GO:1901896) |
| 3.0 | 18.1 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 3.0 | 9.0 | GO:1902309 | regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 3.0 | 116.4 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 3.0 | 3.0 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 2.9 | 14.7 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 2.9 | 8.7 | GO:0045715 | negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
| 2.9 | 17.4 | GO:0052805 | histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805) |
| 2.9 | 2.9 | GO:0000963 | mitochondrial RNA processing(GO:0000963) |
| 2.8 | 48.0 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 2.7 | 24.7 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 2.7 | 24.7 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 2.7 | 30.1 | GO:0051665 | membrane raft localization(GO:0051665) |
| 2.7 | 24.5 | GO:0016559 | peroxisome fission(GO:0016559) |
| 2.7 | 8.1 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) |
| 2.7 | 21.5 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 2.6 | 18.5 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 2.6 | 18.5 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 2.6 | 18.3 | GO:0015677 | copper ion import(GO:0015677) |
| 2.6 | 41.8 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 2.5 | 10.2 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 2.5 | 2.5 | GO:1901355 | response to rapamycin(GO:1901355) |
| 2.5 | 17.5 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 2.5 | 9.9 | GO:0030047 | actin modification(GO:0030047) |
| 2.5 | 7.4 | GO:0060166 | olfactory pit development(GO:0060166) |
| 2.5 | 7.4 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 2.5 | 17.2 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 2.4 | 9.8 | GO:1904116 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 2.4 | 2.4 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
| 2.4 | 2.4 | GO:0046070 | dGTP metabolic process(GO:0046070) |
| 2.4 | 11.9 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 2.4 | 16.6 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 2.3 | 44.1 | GO:0075713 | establishment of integrated proviral latency(GO:0075713) |
| 2.3 | 61.9 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 2.2 | 2.2 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 2.2 | 4.5 | GO:0072244 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
| 2.2 | 4.4 | GO:1903233 | regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) |
| 2.2 | 6.6 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 2.2 | 4.4 | GO:0019249 | lactate biosynthetic process(GO:0019249) |
| 2.2 | 8.7 | GO:0002188 | translation reinitiation(GO:0002188) |
| 2.2 | 175.3 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 2.2 | 4.3 | GO:0007007 | inner mitochondrial membrane organization(GO:0007007) |
| 2.1 | 23.6 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 2.1 | 12.8 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 2.1 | 36.2 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 2.1 | 6.3 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 2.1 | 12.5 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 2.1 | 35.2 | GO:0034389 | lipid particle organization(GO:0034389) |
| 2.1 | 6.2 | GO:0017198 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 2.1 | 10.3 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 2.0 | 10.1 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 2.0 | 48.5 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 2.0 | 6.0 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 2.0 | 29.8 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 2.0 | 6.0 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 2.0 | 11.9 | GO:0006235 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 2.0 | 13.7 | GO:0036258 | multivesicular body assembly(GO:0036258) |
| 2.0 | 7.8 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
| 1.9 | 7.8 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 1.9 | 7.8 | GO:0000393 | spliceosomal conformational changes to generate catalytic conformation(GO:0000393) |
| 1.9 | 5.8 | GO:0051821 | negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) development involved in symbiotic interaction(GO:0044111) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821) |
| 1.9 | 71.3 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 1.9 | 13.5 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 1.9 | 9.5 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 1.9 | 13.3 | GO:0000012 | single strand break repair(GO:0000012) |
| 1.9 | 7.4 | GO:0072319 | synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319) |
| 1.9 | 3.7 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) |
| 1.9 | 16.7 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
| 1.8 | 5.5 | GO:1903565 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 1.8 | 3.7 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 1.8 | 16.4 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 1.8 | 7.3 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
| 1.8 | 23.6 | GO:0042407 | cristae formation(GO:0042407) |
| 1.8 | 10.9 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 1.8 | 9.0 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
| 1.8 | 17.9 | GO:0060717 | chorion development(GO:0060717) |
| 1.8 | 12.4 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 1.8 | 30.1 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 1.8 | 45.5 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
| 1.7 | 1.7 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
| 1.7 | 12.0 | GO:0006662 | glycerol ether metabolic process(GO:0006662) |
| 1.7 | 22.2 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 1.7 | 16.9 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 1.7 | 52.4 | GO:0090383 | phagosome acidification(GO:0090383) |
| 1.7 | 148.1 | GO:0006903 | vesicle targeting(GO:0006903) |
| 1.7 | 5.0 | GO:2000520 | tolerance induction dependent upon immune response(GO:0002461) regulation of immunological synapse formation(GO:2000520) negative regulation of immunological synapse formation(GO:2000521) |
| 1.7 | 58.0 | GO:0070897 | DNA-templated transcriptional preinitiation complex assembly(GO:0070897) |
| 1.7 | 5.0 | GO:0035437 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
| 1.6 | 8.2 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 1.6 | 9.8 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 1.6 | 6.5 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
| 1.6 | 17.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 1.6 | 7.8 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 1.5 | 4.6 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
| 1.5 | 16.9 | GO:0006108 | malate metabolic process(GO:0006108) |
| 1.5 | 38.3 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 1.5 | 16.8 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
| 1.5 | 4.6 | GO:0090341 | negative regulation of secretion of lysosomal enzymes(GO:0090341) |
| 1.5 | 4.5 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 1.5 | 27.2 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 1.5 | 37.7 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 1.5 | 9.0 | GO:0033504 | floor plate development(GO:0033504) |
| 1.5 | 28.4 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 1.5 | 12.0 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
| 1.5 | 5.8 | GO:0071418 | cellular response to amine stimulus(GO:0071418) |
| 1.5 | 20.4 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 1.4 | 21.7 | GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) |
| 1.4 | 15.8 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 1.4 | 17.2 | GO:0070200 | establishment of protein localization to telomere(GO:0070200) |
| 1.4 | 5.7 | GO:0009956 | radial pattern formation(GO:0009956) |
| 1.4 | 20.9 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 1.4 | 14.9 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 1.4 | 8.1 | GO:1904874 | positive regulation of telomerase RNA localization to Cajal body(GO:1904874) |
| 1.4 | 25.7 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
| 1.3 | 6.7 | GO:0035900 | response to isolation stress(GO:0035900) |
| 1.3 | 7.9 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 1.3 | 10.5 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 1.3 | 17.1 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 1.3 | 9.0 | GO:0051013 | microtubule severing(GO:0051013) |
| 1.3 | 2.6 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 1.3 | 22.9 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 1.3 | 8.9 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 1.3 | 13.9 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 1.3 | 7.6 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 1.3 | 3.8 | GO:1903937 | response to acrylamide(GO:1903937) |
| 1.2 | 3.6 | GO:0097032 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
| 1.2 | 7.2 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 1.2 | 16.9 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 1.2 | 10.8 | GO:2001169 | regulation of ATP biosynthetic process(GO:2001169) positive regulation of ATP biosynthetic process(GO:2001171) |
| 1.2 | 10.8 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 1.2 | 30.9 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 1.2 | 3.6 | GO:0072683 | T cell extravasation(GO:0072683) |
| 1.2 | 4.7 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 1.2 | 3.5 | GO:1903537 | meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 1.2 | 21.0 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 1.2 | 31.4 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 1.2 | 10.4 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 1.1 | 4.6 | GO:1900535 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 1.1 | 7.9 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 1.1 | 2.3 | GO:0021896 | forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) |
| 1.1 | 15.7 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 1.1 | 26.6 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 1.1 | 8.9 | GO:0015865 | purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868) |
| 1.1 | 7.7 | GO:0042483 | negative regulation of odontogenesis(GO:0042483) |
| 1.1 | 7.7 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 1.1 | 10.9 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 1.1 | 3.3 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 1.1 | 4.3 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 1.1 | 2.1 | GO:0043465 | fermentation(GO:0006113) regulation of fermentation(GO:0043465) |
| 1.1 | 3.2 | GO:0090261 | positive regulation of inclusion body assembly(GO:0090261) |
| 1.1 | 5.3 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 1.1 | 4.2 | GO:0035627 | ceramide transport(GO:0035627) |
| 1.0 | 31.4 | GO:0031648 | protein destabilization(GO:0031648) |
| 1.0 | 13.5 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 1.0 | 5.2 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 1.0 | 77.3 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 1.0 | 14.4 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 1.0 | 6.1 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
| 1.0 | 39.2 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 1.0 | 68.0 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 1.0 | 12.9 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 1.0 | 4.0 | GO:1900016 | negative regulation of cytokine production involved in inflammatory response(GO:1900016) |
| 1.0 | 14.9 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 1.0 | 20.7 | GO:0000154 | rRNA modification(GO:0000154) |
| 1.0 | 61.8 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 1.0 | 3.9 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 1.0 | 8.8 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 1.0 | 5.8 | GO:1901538 | DNA methylation involved in embryo development(GO:0043045) C-5 methylation of cytosine(GO:0090116) changes to DNA methylation involved in embryo development(GO:1901538) |
| 1.0 | 3.9 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 1.0 | 5.8 | GO:0098881 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 1.0 | 2.9 | GO:0015822 | ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) |
| 1.0 | 73.5 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.9 | 4.7 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.9 | 2.8 | GO:0010041 | response to iron(III) ion(GO:0010041) |
| 0.9 | 9.3 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.9 | 31.7 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.9 | 6.5 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.9 | 41.5 | GO:0043486 | histone exchange(GO:0043486) |
| 0.9 | 13.7 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.9 | 127.9 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.9 | 9.9 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.9 | 6.3 | GO:1903895 | negative regulation of IRE1-mediated unfolded protein response(GO:1903895) |
| 0.9 | 17.1 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
| 0.9 | 4.5 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.9 | 3.6 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.9 | 9.8 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.9 | 3.5 | GO:0021823 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923) |
| 0.9 | 16.8 | GO:0006144 | purine nucleobase metabolic process(GO:0006144) |
| 0.9 | 14.2 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.9 | 8.8 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.9 | 0.9 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.9 | 25.2 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
| 0.9 | 12.2 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 0.9 | 1.7 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.9 | 4.3 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.9 | 3.5 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.9 | 3.5 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.9 | 2.6 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 0.9 | 4.3 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.9 | 23.3 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.9 | 3.4 | GO:0018032 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 0.9 | 5.1 | GO:0072307 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 0.8 | 21.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.8 | 2.5 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 0.8 | 2.5 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.8 | 19.1 | GO:0022900 | electron transport chain(GO:0022900) |
| 0.8 | 9.9 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.8 | 4.1 | GO:0021553 | olfactory nerve development(GO:0021553) |
| 0.8 | 9.0 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.8 | 25.4 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.8 | 16.3 | GO:0017004 | cytochrome complex assembly(GO:0017004) |
| 0.8 | 36.6 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.8 | 3.2 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.8 | 47.3 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.8 | 1.5 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.8 | 2.3 | GO:0036079 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 0.8 | 9.8 | GO:0045008 | depyrimidination(GO:0045008) |
| 0.7 | 6.0 | GO:0001878 | response to yeast(GO:0001878) |
| 0.7 | 5.2 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.7 | 22.1 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.7 | 0.7 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 0.7 | 1.4 | GO:0070945 | neutrophil mediated killing of gram-negative bacterium(GO:0070945) |
| 0.7 | 7.9 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.7 | 1.4 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.7 | 2.1 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.7 | 51.1 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.7 | 2.8 | GO:0072093 | ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093) |
| 0.7 | 5.5 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.7 | 7.5 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.7 | 3.4 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.7 | 6.7 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.7 | 3.3 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.7 | 2.6 | GO:1904980 | regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980) |
| 0.7 | 2.0 | GO:0090027 | negative regulation of monocyte chemotaxis(GO:0090027) |
| 0.7 | 19.0 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.7 | 11.1 | GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) |
| 0.6 | 3.2 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.6 | 7.1 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.6 | 18.1 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.6 | 3.2 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) negative regulation of vasoconstriction(GO:0045906) |
| 0.6 | 1.3 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 0.6 | 7.1 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.6 | 12.8 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.6 | 3.8 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.6 | 0.6 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.6 | 1.9 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
| 0.6 | 1.9 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 0.6 | 1.9 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.6 | 11.9 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.6 | 0.6 | GO:1904908 | negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of telomeric DNA binding(GO:1904742) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908) |
| 0.6 | 7.3 | GO:0015825 | L-serine transport(GO:0015825) |
| 0.6 | 1.8 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 0.6 | 6.7 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.6 | 2.4 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.6 | 8.3 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.6 | 27.1 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
| 0.6 | 5.9 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.6 | 1.2 | GO:0031627 | telomeric loop formation(GO:0031627) |
| 0.6 | 11.7 | GO:2000674 | type B pancreatic cell apoptotic process(GO:0097050) regulation of type B pancreatic cell apoptotic process(GO:2000674) |
| 0.6 | 2.3 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.6 | 5.2 | GO:0002934 | desmosome organization(GO:0002934) |
| 0.6 | 1.1 | GO:0015747 | urate transport(GO:0015747) |
| 0.6 | 10.7 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.6 | 2.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.6 | 1.1 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.6 | 6.8 | GO:0035878 | nail development(GO:0035878) |
| 0.6 | 25.6 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.6 | 15.0 | GO:0030539 | male genitalia development(GO:0030539) |
| 0.6 | 12.8 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.6 | 2.2 | GO:0034201 | response to oleic acid(GO:0034201) |
| 0.5 | 4.4 | GO:0007070 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 0.5 | 1.6 | GO:0044854 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) |
| 0.5 | 5.4 | GO:1900227 | positive regulation of NLRP3 inflammasome complex assembly(GO:1900227) |
| 0.5 | 0.5 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 0.5 | 2.1 | GO:0046946 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.5 | 8.9 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.5 | 1.6 | GO:0034135 | regulation of toll-like receptor 2 signaling pathway(GO:0034135) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137) |
| 0.5 | 2.1 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.5 | 3.6 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.5 | 3.6 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.5 | 5.7 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.5 | 27.6 | GO:1990090 | cellular response to nerve growth factor stimulus(GO:1990090) |
| 0.5 | 1.0 | GO:0061643 | chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643) |
| 0.5 | 13.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.5 | 0.5 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 0.5 | 20.5 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.5 | 13.5 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 0.5 | 3.4 | GO:1902855 | nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.5 | 4.8 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 0.5 | 4.3 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.5 | 2.3 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 0.5 | 2.8 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.5 | 5.5 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.4 | 1.3 | GO:1903677 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.4 | 12.9 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.4 | 18.6 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) |
| 0.4 | 6.6 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.4 | 2.2 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.4 | 1.3 | GO:0061101 | neuroendocrine cell differentiation(GO:0061101) |
| 0.4 | 6.0 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.4 | 3.0 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.4 | 6.4 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.4 | 1.7 | GO:1990502 | dense core granule maturation(GO:1990502) |
| 0.4 | 2.9 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 0.4 | 1.2 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.4 | 5.3 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.4 | 4.1 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.4 | 9.0 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.4 | 2.4 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.4 | 10.9 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.4 | 7.7 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.4 | 3.2 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.4 | 3.6 | GO:0035825 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
| 0.4 | 6.0 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.4 | 10.7 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.4 | 4.4 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.4 | 3.9 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.4 | 2.0 | GO:0090037 | response to cobalamin(GO:0033590) positive regulation of protein kinase C signaling(GO:0090037) |
| 0.4 | 1.9 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.4 | 5.0 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.4 | 0.4 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
| 0.4 | 0.4 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.4 | 1.5 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.4 | 0.8 | GO:0085020 | protein K6-linked ubiquitination(GO:0085020) |
| 0.4 | 4.8 | GO:0031114 | negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114) |
| 0.4 | 1.5 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.4 | 1.5 | GO:0034444 | regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) |
| 0.4 | 5.8 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.4 | 4.6 | GO:0009452 | 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 0.4 | 2.8 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.3 | 2.4 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.3 | 2.8 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.3 | 2.4 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.3 | 4.8 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.3 | 31.4 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.3 | 2.7 | GO:0061709 | reticulophagy(GO:0061709) |
| 0.3 | 59.9 | GO:0006457 | protein folding(GO:0006457) |
| 0.3 | 1.0 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.3 | 1.3 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
| 0.3 | 3.0 | GO:0031033 | myosin filament organization(GO:0031033) |
| 0.3 | 2.9 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.3 | 1.9 | GO:0061743 | motor learning(GO:0061743) |
| 0.3 | 6.6 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.3 | 1.6 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.3 | 1.9 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.3 | 1.5 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.3 | 35.9 | GO:0030282 | bone mineralization(GO:0030282) |
| 0.3 | 2.8 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.3 | 3.3 | GO:2000795 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.3 | 3.0 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.3 | 5.3 | GO:0048490 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.3 | 7.7 | GO:0097484 | dendrite extension(GO:0097484) |
| 0.3 | 18.9 | GO:0055007 | cardiac muscle cell differentiation(GO:0055007) |
| 0.3 | 0.3 | GO:0098507 | polynucleotide 5' dephosphorylation(GO:0098507) |
| 0.3 | 1.8 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 0.3 | 6.8 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.3 | 98.1 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 0.3 | 9.0 | GO:0042733 | embryonic digit morphogenesis(GO:0042733) |
| 0.3 | 9.6 | GO:0051220 | cytoplasmic sequestering of protein(GO:0051220) |
| 0.3 | 12.1 | GO:0018196 | peptidyl-asparagine modification(GO:0018196) |
| 0.3 | 2.3 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.3 | 1.7 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.3 | 1.4 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.3 | 7.7 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.3 | 7.6 | GO:0060976 | coronary vasculature development(GO:0060976) |
| 0.3 | 7.3 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
| 0.3 | 3.3 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.3 | 1.1 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 0.3 | 1.4 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.3 | 25.3 | GO:0046546 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.3 | 3.8 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.3 | 1.1 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.3 | 0.8 | GO:0042946 | glucoside transport(GO:0042946) |
| 0.3 | 4.1 | GO:1903206 | negative regulation of hydrogen peroxide-induced cell death(GO:1903206) |
| 0.3 | 0.5 | GO:0044154 | histone H3-K14 acetylation(GO:0044154) |
| 0.3 | 0.5 | GO:0036119 | response to platelet-derived growth factor(GO:0036119) |
| 0.3 | 3.6 | GO:0044819 | mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819) |
| 0.3 | 1.8 | GO:0046618 | drug export(GO:0046618) |
| 0.3 | 2.5 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.2 | 5.0 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.2 | 7.1 | GO:0031398 | positive regulation of protein ubiquitination(GO:0031398) |
| 0.2 | 0.7 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.2 | 1.4 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.2 | 5.2 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.2 | 1.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.2 | 1.9 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.2 | 33.7 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.2 | 0.7 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.2 | 1.4 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
| 0.2 | 2.6 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.2 | 1.8 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.2 | 1.1 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.2 | 5.0 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.2 | 1.9 | GO:0090042 | tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043) |
| 0.2 | 2.1 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.2 | 1.3 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.2 | 6.6 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.2 | 1.3 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.2 | 1.1 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.2 | 2.4 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.2 | 1.0 | GO:1904304 | long-chain fatty acid import(GO:0044539) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) |
| 0.2 | 1.2 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 0.2 | 7.0 | GO:0006693 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.2 | 1.7 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.2 | 5.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.2 | 30.6 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.2 | 0.8 | GO:0009305 | protein biotinylation(GO:0009305) histone biotinylation(GO:0071110) |
| 0.2 | 11.2 | GO:0007338 | single fertilization(GO:0007338) |
| 0.2 | 0.5 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.2 | 4.7 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.2 | 0.5 | GO:1904814 | regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 0.2 | 2.4 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
| 0.2 | 0.5 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.2 | 1.7 | GO:0033363 | secretory granule organization(GO:0033363) |
| 0.2 | 3.3 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.2 | 1.5 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.2 | 3.2 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.2 | 1.1 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.2 | 5.7 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.2 | 0.9 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
| 0.2 | 0.3 | GO:0042710 | biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) |
| 0.1 | 1.0 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.1 | 0.7 | GO:0070091 | glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092) |
| 0.1 | 0.1 | GO:0072513 | regulation of secondary heart field cardioblast proliferation(GO:0003266) positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.1 | 5.7 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 1.1 | GO:0031397 | negative regulation of protein ubiquitination(GO:0031397) |
| 0.1 | 4.3 | GO:0000726 | non-recombinational repair(GO:0000726) |
| 0.1 | 0.3 | GO:1904031 | positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
| 0.1 | 7.0 | GO:0030516 | regulation of axon extension(GO:0030516) |
| 0.1 | 9.0 | GO:0007286 | spermatid development(GO:0007286) |
| 0.1 | 0.1 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 0.1 | 0.4 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 0.1 | 0.8 | GO:0019732 | antifungal humoral response(GO:0019732) |
| 0.1 | 0.9 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 1.0 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) retina vasculature development in camera-type eye(GO:0061298) |
| 0.1 | 0.9 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 1.1 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 0.1 | 0.7 | GO:0009223 | pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
| 0.1 | 1.3 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.1 | 0.6 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.1 | 0.6 | GO:0098840 | intraciliary transport(GO:0042073) protein transport along microtubule(GO:0098840) |
| 0.1 | 6.0 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 0.7 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.1 | 1.6 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 0.7 | GO:0007184 | SMAD protein import into nucleus(GO:0007184) |
| 0.1 | 0.4 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.1 | 0.4 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.1 | 0.9 | GO:0001996 | positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) |
| 0.1 | 2.9 | GO:0007040 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 0.2 | GO:0021764 | amygdala development(GO:0021764) |
| 0.1 | 0.6 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.1 | 0.3 | GO:0042320 | vestibulocochlear nerve development(GO:0021562) positive regulation of dopamine secretion(GO:0033603) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) |
| 0.1 | 0.7 | GO:0051310 | metaphase plate congression(GO:0051310) |
| 0.1 | 2.4 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.1 | 0.7 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 1.3 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.1 | 5.5 | GO:0006333 | chromatin assembly or disassembly(GO:0006333) |
| 0.1 | 4.0 | GO:0002209 | behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) |
| 0.1 | 1.7 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.1 | 2.3 | GO:0042438 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
| 0.1 | 0.2 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.1 | 1.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 0.8 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.1 | 2.7 | GO:0008542 | visual learning(GO:0008542) |
| 0.1 | 2.0 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.1 | 0.7 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.1 | 1.7 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.1 | 0.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 0.4 | GO:0016246 | RNA interference(GO:0016246) |
| 0.1 | 0.7 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) |
| 0.1 | 1.1 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.1 | 11.0 | GO:0007283 | spermatogenesis(GO:0007283) male gamete generation(GO:0048232) |
| 0.1 | 0.4 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.1 | 0.1 | GO:0051280 | negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) |
| 0.1 | 0.3 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.1 | 0.5 | GO:0045333 | cellular respiration(GO:0045333) |
| 0.1 | 0.1 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.1 | 0.5 | GO:0060080 | inhibitory postsynaptic potential(GO:0060080) |
| 0.1 | 0.4 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
| 0.1 | 1.9 | GO:0051932 | synaptic transmission, GABAergic(GO:0051932) |
| 0.1 | 1.3 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 2.1 | GO:0001938 | positive regulation of endothelial cell proliferation(GO:0001938) |
| 0.1 | 0.4 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.0 | 1.8 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 0.3 | GO:1904259 | positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.9 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 1.5 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.0 | 0.3 | GO:0042426 | choline catabolic process(GO:0042426) |
| 0.0 | 1.0 | GO:0015800 | acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813) |
| 0.0 | 0.2 | GO:0009070 | serine family amino acid biosynthetic process(GO:0009070) |
| 0.0 | 1.4 | GO:0008344 | adult locomotory behavior(GO:0008344) |
| 0.0 | 0.1 | GO:0090285 | regulation of protein glycosylation in Golgi(GO:0090283) negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.0 | 4.5 | GO:0090305 | nucleic acid phosphodiester bond hydrolysis(GO:0090305) |
| 0.0 | 1.0 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 0.5 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.0 | 0.6 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
| 0.0 | 0.4 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.7 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.0 | 0.2 | GO:0051934 | dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494) |
| 0.0 | 0.8 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.4 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.1 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.0 | 0.3 | GO:0051004 | regulation of lipoprotein lipase activity(GO:0051004) |
| 0.0 | 1.5 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.0 | 3.8 | GO:0032446 | protein modification by small protein conjugation(GO:0032446) |
| 0.0 | 0.0 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.0 | 0.4 | GO:0001935 | endothelial cell proliferation(GO:0001935) |
| 0.0 | 0.2 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.0 | 0.1 | GO:0060426 | lung vasculature development(GO:0060426) lung saccule development(GO:0060430) eyelid development in camera-type eye(GO:0061029) alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205) |
| 0.0 | 0.4 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.6 | 68.0 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 11.1 | 33.2 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 11.1 | 110.5 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 10.0 | 30.1 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 8.8 | 61.7 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 8.7 | 61.0 | GO:0016272 | prefoldin complex(GO:0016272) |
| 8.0 | 24.1 | GO:0097441 | basilar dendrite(GO:0097441) |
| 7.9 | 39.4 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 7.7 | 23.2 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 7.3 | 51.1 | GO:0032021 | NELF complex(GO:0032021) |
| 7.3 | 79.9 | GO:0070449 | elongin complex(GO:0070449) |
| 7.2 | 21.5 | GO:0030689 | Noc complex(GO:0030689) |
| 6.9 | 61.9 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 6.8 | 20.3 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 6.6 | 85.3 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 6.5 | 26.2 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 6.4 | 70.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 6.4 | 57.3 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 6.3 | 63.4 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 6.2 | 86.5 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 6.1 | 24.5 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 6.0 | 18.0 | GO:0018444 | translation release factor complex(GO:0018444) |
| 5.7 | 28.6 | GO:0070847 | core mediator complex(GO:0070847) |
| 5.6 | 28.1 | GO:0032044 | DSIF complex(GO:0032044) |
| 5.6 | 56.0 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 5.5 | 21.9 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 5.3 | 95.0 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 5.1 | 30.3 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 4.9 | 54.4 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 4.9 | 24.3 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 4.8 | 76.6 | GO:0034709 | methylosome(GO:0034709) |
| 4.8 | 23.9 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 4.8 | 23.8 | GO:0032449 | CBM complex(GO:0032449) |
| 4.8 | 19.0 | GO:0071920 | cleavage body(GO:0071920) |
| 4.6 | 13.7 | GO:0071817 | MMXD complex(GO:0071817) |
| 4.5 | 22.7 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 4.5 | 40.6 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 4.4 | 21.8 | GO:0014802 | terminal cisterna(GO:0014802) |
| 4.3 | 171.9 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 4.2 | 58.7 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 4.1 | 12.4 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 4.1 | 32.9 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 4.1 | 36.8 | GO:0032797 | SMN complex(GO:0032797) |
| 3.9 | 85.4 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 3.7 | 37.2 | GO:0043203 | axon hillock(GO:0043203) |
| 3.7 | 33.4 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 3.7 | 29.4 | GO:0097443 | sorting endosome(GO:0097443) |
| 3.6 | 67.9 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 3.6 | 39.2 | GO:0022624 | proteasome accessory complex(GO:0022624) |
| 3.6 | 10.7 | GO:0032419 | extrinsic component of lysosome membrane(GO:0032419) |
| 3.5 | 67.3 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 3.5 | 7.1 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
| 3.5 | 28.1 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 3.5 | 31.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 3.4 | 20.4 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 3.4 | 16.8 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 3.3 | 10.0 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 3.3 | 60.0 | GO:0005685 | U1 snRNP(GO:0005685) |
| 3.3 | 10.0 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 3.3 | 29.8 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 3.3 | 29.7 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 3.3 | 52.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 3.2 | 22.6 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 3.2 | 12.9 | GO:0070876 | SOSS complex(GO:0070876) |
| 3.2 | 9.5 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 3.1 | 166.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 3.0 | 39.1 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 2.9 | 11.7 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 2.9 | 23.4 | GO:0034464 | BBSome(GO:0034464) |
| 2.9 | 8.7 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 2.9 | 63.3 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 2.9 | 25.8 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 2.9 | 22.8 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 2.9 | 17.1 | GO:0061617 | MICOS complex(GO:0061617) |
| 2.7 | 27.0 | GO:0097255 | R2TP complex(GO:0097255) |
| 2.6 | 18.4 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 2.5 | 81.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 2.4 | 7.3 | GO:0034455 | t-UTP complex(GO:0034455) |
| 2.3 | 18.5 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522) |
| 2.3 | 25.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 2.2 | 6.6 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 2.2 | 24.1 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 2.2 | 15.3 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 2.2 | 50.0 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 2.1 | 25.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 2.0 | 8.1 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 2.0 | 25.9 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 2.0 | 11.9 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 2.0 | 21.8 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 2.0 | 7.9 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 2.0 | 5.9 | GO:0000243 | commitment complex(GO:0000243) |
| 2.0 | 43.0 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 1.9 | 11.5 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 1.9 | 22.8 | GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178) |
| 1.9 | 5.6 | GO:0016938 | kinesin I complex(GO:0016938) |
| 1.8 | 16.5 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 1.8 | 12.8 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 1.8 | 1.8 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 1.8 | 35.9 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 1.8 | 8.8 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 1.8 | 14.1 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 1.8 | 24.7 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 1.8 | 30.0 | GO:0005839 | proteasome core complex(GO:0005839) |
| 1.8 | 7.0 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 1.7 | 8.7 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 1.7 | 5.1 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 1.6 | 6.5 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 1.6 | 40.0 | GO:0044295 | axonal growth cone(GO:0044295) |
| 1.6 | 22.0 | GO:0030914 | STAGA complex(GO:0030914) |
| 1.6 | 36.0 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 1.6 | 12.5 | GO:0000796 | condensin complex(GO:0000796) |
| 1.6 | 43.5 | GO:0032040 | small-subunit processome(GO:0032040) |
| 1.6 | 23.3 | GO:0000812 | Swr1 complex(GO:0000812) |
| 1.5 | 13.8 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 1.5 | 4.5 | GO:0043260 | laminin-11 complex(GO:0043260) |
| 1.5 | 8.9 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 1.5 | 7.4 | GO:0005749 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 1.5 | 10.3 | GO:1990745 | EARP complex(GO:1990745) |
| 1.4 | 28.3 | GO:0033176 | proton-transporting V-type ATPase complex(GO:0033176) |
| 1.4 | 12.7 | GO:0033391 | chromatoid body(GO:0033391) |
| 1.4 | 2.8 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 1.4 | 14.0 | GO:0043186 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 1.4 | 5.6 | GO:0071986 | Ragulator complex(GO:0071986) |
| 1.4 | 8.4 | GO:0071797 | LUBAC complex(GO:0071797) |
| 1.4 | 46.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 1.4 | 10.8 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 1.3 | 10.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 1.3 | 7.9 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 1.3 | 6.6 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 1.3 | 65.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 1.3 | 20.5 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 1.3 | 3.8 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 1.3 | 7.6 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 1.3 | 64.3 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 1.2 | 3.7 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 1.2 | 7.4 | GO:0070552 | BRISC complex(GO:0070552) |
| 1.2 | 6.1 | GO:0042587 | glycogen granule(GO:0042587) |
| 1.2 | 59.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 1.2 | 4.6 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 1.2 | 5.8 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 1.1 | 29.6 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 1.1 | 15.0 | GO:0036452 | ESCRT complex(GO:0036452) |
| 1.1 | 28.8 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 1.0 | 17.7 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 1.0 | 3.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 1.0 | 9.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 1.0 | 58.3 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 1.0 | 11.6 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.9 | 3.8 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.9 | 8.5 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.9 | 9.3 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.9 | 49.7 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.9 | 41.7 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.9 | 3.5 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.9 | 1.7 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 0.8 | 26.1 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.8 | 3.3 | GO:0070695 | FHF complex(GO:0070695) |
| 0.8 | 2.5 | GO:0031211 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.8 | 8.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.8 | 12.7 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.8 | 25.0 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.8 | 3.9 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.8 | 36.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.8 | 3.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.7 | 3.7 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.7 | 2.2 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.7 | 8.0 | GO:0042555 | MCM complex(GO:0042555) |
| 0.7 | 9.3 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.7 | 14.7 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.7 | 50.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.7 | 24.9 | GO:0016592 | mediator complex(GO:0016592) |
| 0.7 | 11.6 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.7 | 201.0 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.7 | 13.5 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.7 | 31.3 | GO:0005844 | polysome(GO:0005844) |
| 0.7 | 5.9 | GO:0032009 | early phagosome(GO:0032009) |
| 0.7 | 23.0 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.6 | 3.9 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.6 | 1.9 | GO:0000805 | X chromosome(GO:0000805) cyclin E2-CDK2 complex(GO:0097135) |
| 0.6 | 8.8 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.6 | 97.8 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.6 | 6.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.6 | 1.8 | GO:0000801 | central element(GO:0000801) |
| 0.6 | 9.8 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.6 | 18.8 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.6 | 3.6 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.6 | 5.3 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.6 | 5.8 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.6 | 5.7 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.6 | 1.7 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.6 | 12.3 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.6 | 18.4 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.6 | 9.4 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.6 | 4.4 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.6 | 6.6 | GO:0090543 | Flemming body(GO:0090543) |
| 0.5 | 4.9 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.5 | 5.5 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.5 | 13.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.5 | 15.9 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.5 | 14.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.5 | 12.3 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.5 | 7.1 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.5 | 1.9 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.5 | 8.0 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.5 | 6.1 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.5 | 2.8 | GO:0033063 | DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.5 | 13.0 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.5 | 3.2 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.5 | 2.3 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.4 | 4.0 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.4 | 5.3 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.4 | 1.7 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.4 | 3.9 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.4 | 13.4 | GO:0032420 | stereocilium(GO:0032420) |
| 0.4 | 5.1 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.4 | 18.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.4 | 7.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.4 | 5.7 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.4 | 1.6 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.4 | 6.7 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.4 | 24.2 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.4 | 41.3 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.4 | 6.9 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.4 | 1.1 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 0.4 | 2.2 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.4 | 4.7 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.4 | 1.5 | GO:0060091 | kinocilium(GO:0060091) |
| 0.4 | 17.5 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.4 | 1.5 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.4 | 204.5 | GO:0044429 | mitochondrial part(GO:0044429) |
| 0.4 | 42.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.4 | 1.8 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.3 | 2.1 | GO:0031313 | extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313) |
| 0.3 | 5.5 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.3 | 6.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.3 | 4.7 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.3 | 13.1 | GO:0016235 | aggresome(GO:0016235) |
| 0.3 | 4.0 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.3 | 5.3 | GO:0005922 | connexon complex(GO:0005922) |
| 0.3 | 88.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.3 | 5.2 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.3 | 3.8 | GO:0005883 | neurofilament(GO:0005883) |
| 0.3 | 2.8 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.3 | 5.3 | GO:0000145 | exocyst(GO:0000145) |
| 0.3 | 13.1 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.3 | 3.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.3 | 1.8 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.3 | 11.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.3 | 21.2 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.3 | 11.4 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.2 | 1.5 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.2 | 5.1 | GO:0005861 | troponin complex(GO:0005861) |
| 0.2 | 4.2 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.2 | 11.5 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.2 | 29.6 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.2 | 6.0 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.2 | 0.9 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.2 | 31.1 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.2 | 30.4 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.2 | 20.5 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.2 | 0.6 | GO:0098536 | deuterosome(GO:0098536) |
| 0.2 | 3.3 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.2 | 1.2 | GO:0030684 | preribosome(GO:0030684) |
| 0.2 | 18.5 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.2 | 2.6 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.2 | 52.3 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.2 | 8.1 | GO:0005901 | caveola(GO:0005901) |
| 0.2 | 16.2 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.2 | 9.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 2.9 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.2 | 2.5 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.2 | 24.1 | GO:0030018 | Z disc(GO:0030018) |
| 0.2 | 34.6 | GO:0005874 | microtubule(GO:0005874) |
| 0.2 | 1.8 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 15.9 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.2 | 96.8 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.1 | 1.0 | GO:0032059 | bleb(GO:0032059) |
| 0.1 | 0.6 | GO:0044447 | axoneme part(GO:0044447) |
| 0.1 | 4.5 | GO:0031514 | motile cilium(GO:0031514) |
| 0.1 | 32.1 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.1 | 1.0 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 64.9 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.1 | 2.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 0.5 | GO:1990879 | CST complex(GO:1990879) |
| 0.1 | 6.3 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.1 | 3.1 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 0.7 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.1 | 1.0 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 5.9 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 4.5 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 0.6 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.1 | 0.3 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 0.1 | 0.6 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 0.3 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.1 | 2.3 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 1.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 0.2 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.1 | 9.0 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 0.6 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 0.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.9 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 0.5 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.0 | 1.4 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.3 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 0.9 | GO:0044291 | cell-cell contact zone(GO:0044291) |
| 0.0 | 0.1 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 0.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 10.6 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 0.5 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.1 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 0.4 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 1.8 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 3.8 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.0 | 0.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 21.5 | 64.5 | GO:0034416 | bisphosphoglycerate phosphatase activity(GO:0034416) |
| 14.3 | 43.0 | GO:0044714 | GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693) |
| 11.9 | 35.7 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 11.8 | 59.1 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 11.7 | 58.3 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 11.1 | 33.2 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 10.0 | 30.1 | GO:0031753 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 9.9 | 49.3 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 9.4 | 84.2 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 8.4 | 8.4 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 7.5 | 22.6 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 7.4 | 37.2 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 7.3 | 21.8 | GO:0004750 | ribulose-phosphate 3-epimerase activity(GO:0004750) |
| 7.3 | 43.6 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 6.9 | 41.5 | GO:0016807 | cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) |
| 6.7 | 60.7 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 6.6 | 39.5 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 6.4 | 19.3 | GO:0052815 | medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816) |
| 5.6 | 44.9 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 5.4 | 37.8 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 5.4 | 21.6 | GO:0004146 | dihydrofolate reductase activity(GO:0004146) |
| 5.2 | 31.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 5.1 | 40.9 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 5.1 | 35.6 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 4.9 | 14.8 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 4.6 | 27.8 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 4.6 | 22.9 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 4.5 | 13.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 4.5 | 31.3 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 4.4 | 13.3 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 4.1 | 24.5 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 4.0 | 11.9 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 3.9 | 23.4 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 3.9 | 11.6 | GO:0015137 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 3.9 | 19.3 | GO:0031544 | peptidyl-proline 3-dioxygenase activity(GO:0031544) |
| 3.8 | 30.6 | GO:0071253 | connexin binding(GO:0071253) |
| 3.6 | 18.2 | GO:0034046 | poly(G) binding(GO:0034046) |
| 3.5 | 14.1 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 3.5 | 119.6 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 3.5 | 10.5 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 3.5 | 7.0 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 3.5 | 38.3 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 3.4 | 17.2 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 3.4 | 23.8 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 3.4 | 16.9 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 3.4 | 16.8 | GO:0016657 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 3.4 | 10.1 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 3.3 | 23.3 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 3.3 | 16.7 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 3.3 | 52.3 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 3.2 | 16.2 | GO:0001016 | RNA polymerase III regulatory region DNA binding(GO:0001016) |
| 3.2 | 22.6 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 3.2 | 91.5 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 3.0 | 9.0 | GO:0055100 | adiponectin binding(GO:0055100) |
| 3.0 | 14.9 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 3.0 | 17.8 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 2.9 | 29.1 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 2.9 | 8.7 | GO:0071566 | UFM1 activating enzyme activity(GO:0071566) |
| 2.9 | 60.5 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 2.8 | 102.1 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 2.8 | 16.8 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 2.8 | 13.9 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 2.8 | 30.3 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 2.7 | 21.9 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 2.7 | 27.4 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 2.7 | 75.7 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 2.6 | 59.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 2.6 | 20.7 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 2.5 | 30.4 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 2.5 | 25.3 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 2.5 | 72.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 2.5 | 60.0 | GO:0000339 | RNA cap binding(GO:0000339) |
| 2.5 | 12.3 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 2.4 | 26.8 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 2.4 | 9.8 | GO:0000702 | oxidized base lesion DNA N-glycosylase activity(GO:0000702) |
| 2.4 | 7.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 2.4 | 4.8 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 2.4 | 7.2 | GO:0003978 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 2.4 | 33.1 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 2.3 | 11.7 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 2.3 | 2.3 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 2.3 | 18.5 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 2.3 | 6.8 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 2.3 | 47.5 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 2.3 | 36.1 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
| 2.2 | 37.5 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 2.2 | 8.7 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 2.1 | 23.6 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 2.1 | 12.8 | GO:0016748 | succinyltransferase activity(GO:0016748) |
| 2.1 | 4.2 | GO:0097001 | ceramide binding(GO:0097001) |
| 2.1 | 8.3 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 2.1 | 6.2 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 2.1 | 33.0 | GO:0070513 | death domain binding(GO:0070513) |
| 2.1 | 6.2 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 2.0 | 7.9 | GO:0035473 | lipase binding(GO:0035473) |
| 2.0 | 5.9 | GO:0035375 | zymogen binding(GO:0035375) |
| 2.0 | 25.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 1.9 | 15.3 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 1.9 | 9.5 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 1.9 | 68.3 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 1.8 | 7.4 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 1.8 | 37.6 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 1.8 | 103.0 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 1.7 | 30.9 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 1.7 | 20.4 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 1.7 | 13.5 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 1.7 | 16.6 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 1.6 | 29.6 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 1.6 | 9.8 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 1.6 | 28.8 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 1.6 | 4.7 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 1.6 | 7.9 | GO:0010340 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 1.6 | 6.3 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 1.6 | 20.3 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
| 1.6 | 7.8 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 1.6 | 4.7 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 1.5 | 6.2 | GO:0004773 | steryl-sulfatase activity(GO:0004773) |
| 1.5 | 42.2 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 1.5 | 4.5 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 1.5 | 11.9 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 1.5 | 1.5 | GO:0001034 | RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034) |
| 1.5 | 5.8 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 1.5 | 17.4 | GO:0031386 | protein tag(GO:0031386) |
| 1.4 | 17.4 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 1.4 | 7.2 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
| 1.4 | 34.2 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 1.4 | 11.3 | GO:0003696 | satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237) |
| 1.4 | 84.5 | GO:0004527 | exonuclease activity(GO:0004527) |
| 1.4 | 28.0 | GO:0043495 | protein anchor(GO:0043495) |
| 1.4 | 143.9 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 1.4 | 9.7 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 1.4 | 168.6 | GO:0008565 | protein transporter activity(GO:0008565) |
| 1.4 | 8.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 1.3 | 10.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 1.3 | 12.1 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 1.3 | 18.7 | GO:0046790 | virion binding(GO:0046790) |
| 1.3 | 17.2 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 1.3 | 68.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 1.3 | 6.6 | GO:0008469 | histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 1.3 | 1.3 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 1.3 | 37.3 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 1.3 | 18.0 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 1.3 | 9.0 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 1.3 | 52.5 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 1.3 | 5.1 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 1.2 | 3.7 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
| 1.2 | 3.7 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 1.2 | 6.1 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 1.2 | 16.8 | GO:0030515 | snoRNA binding(GO:0030515) |
| 1.2 | 9.5 | GO:0052832 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 1.2 | 18.9 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 1.2 | 3.5 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 1.2 | 4.7 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 1.2 | 11.7 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 1.2 | 55.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 1.1 | 4.6 | GO:0032810 | sterol response element binding(GO:0032810) |
| 1.1 | 13.5 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 1.1 | 16.9 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 1.1 | 5.6 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 1.0 | 7.3 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 1.0 | 61.0 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 1.0 | 6.1 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 1.0 | 3.0 | GO:0002135 | CTP binding(GO:0002135) |
| 1.0 | 12.0 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 1.0 | 2.0 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 1.0 | 5.0 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 1.0 | 7.9 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 1.0 | 9.7 | GO:0042731 | PH domain binding(GO:0042731) |
| 1.0 | 2.9 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
| 0.9 | 6.6 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.9 | 8.5 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.9 | 2.8 | GO:0016822 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.9 | 2.8 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.9 | 40.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.9 | 89.8 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.9 | 55.1 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.9 | 2.8 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.9 | 30.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.9 | 25.1 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.9 | 1.8 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 0.9 | 13.6 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.9 | 5.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.9 | 6.3 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.9 | 36.9 | GO:0043531 | ADP binding(GO:0043531) |
| 0.9 | 8.9 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.9 | 3.5 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.9 | 48.5 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.9 | 2.6 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.9 | 3.4 | GO:0004598 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.9 | 8.6 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.8 | 3.3 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.8 | 4.1 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.8 | 15.6 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.8 | 8.0 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.8 | 5.5 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.8 | 2.4 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.8 | 18.8 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.8 | 7.8 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.8 | 17.8 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.8 | 2.3 | GO:0005457 | GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080) |
| 0.8 | 3.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.8 | 2.3 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 0.8 | 6.8 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.8 | 3.8 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.8 | 15.8 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.7 | 5.2 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.7 | 18.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.7 | 26.2 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.7 | 31.9 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.7 | 10.8 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.7 | 15.4 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.7 | 70.9 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.7 | 3.5 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.7 | 4.8 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.7 | 0.7 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
| 0.7 | 2.6 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.7 | 4.6 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.6 | 13.6 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.6 | 3.9 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.6 | 5.2 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.6 | 7.6 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.6 | 3.1 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 0.6 | 8.0 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.6 | 7.3 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.6 | 15.6 | GO:0071617 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.6 | 2.9 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.6 | 8.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.6 | 29.5 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.6 | 35.8 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.6 | 12.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.6 | 4.0 | GO:0015288 | porin activity(GO:0015288) |
| 0.6 | 249.8 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.6 | 2.2 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.6 | 5.0 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
| 0.5 | 1.6 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.5 | 3.2 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.5 | 2.7 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.5 | 14.5 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.5 | 2.7 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.5 | 2.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211) |
| 0.5 | 7.9 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.5 | 5.8 | GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
| 0.5 | 1.6 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
| 0.5 | 44.3 | GO:0015405 | primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.5 | 2.6 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.5 | 2.5 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.5 | 39.1 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.5 | 14.0 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.5 | 1.0 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.5 | 7.5 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.5 | 5.3 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.5 | 1.4 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.5 | 6.1 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.5 | 3.8 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.5 | 1.9 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.5 | 8.8 | GO:0005522 | profilin binding(GO:0005522) |
| 0.5 | 5.5 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.4 | 1.8 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.4 | 3.5 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.4 | 2.2 | GO:0016453 | C-acetyltransferase activity(GO:0016453) |
| 0.4 | 2.6 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.4 | 5.5 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.4 | 3.4 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.4 | 1.7 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.4 | 28.0 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.4 | 7.2 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.4 | 7.2 | GO:0019787 | ubiquitin-like protein transferase activity(GO:0019787) |
| 0.4 | 9.0 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.4 | 19.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.4 | 1.5 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.4 | 1.5 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.4 | 5.9 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.4 | 2.6 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.4 | 5.1 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.4 | 4.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.4 | 1.5 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.4 | 2.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.4 | 1.1 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 0.3 | 0.7 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
| 0.3 | 1.0 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.3 | 3.0 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.3 | 22.2 | GO:0019003 | GDP binding(GO:0019003) |
| 0.3 | 5.6 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 0.3 | 1.3 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.3 | 1.9 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.3 | 3.5 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.3 | 2.8 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.3 | 7.8 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.3 | 9.2 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.3 | 28.7 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.3 | 27.2 | GO:0044389 | ubiquitin-like protein ligase binding(GO:0044389) |
| 0.3 | 1.4 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.3 | 13.7 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.3 | 3.1 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.3 | 6.8 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.3 | 1.4 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.3 | 3.0 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.3 | 1.9 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 0.3 | 1.9 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.3 | 2.4 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.3 | 5.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.3 | 16.4 | GO:0034212 | peptide N-acetyltransferase activity(GO:0034212) |
| 0.3 | 4.2 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.3 | 0.8 | GO:0042947 | glucoside transmembrane transporter activity(GO:0042947) |
| 0.3 | 7.2 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.3 | 4.6 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.3 | 1.8 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.3 | 6.8 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.3 | 11.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.3 | 35.0 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.3 | 44.3 | GO:0004857 | enzyme inhibitor activity(GO:0004857) |
| 0.3 | 2.3 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.2 | 2.0 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.2 | 20.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.2 | 1.0 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.2 | 2.0 | GO:0016015 | morphogen activity(GO:0016015) BMP binding(GO:0036122) |
| 0.2 | 5.5 | GO:0033612 | receptor serine/threonine kinase binding(GO:0033612) |
| 0.2 | 12.0 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
| 0.2 | 3.2 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.2 | 22.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 0.4 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.2 | 4.4 | GO:0070888 | E-box binding(GO:0070888) |
| 0.2 | 0.7 | GO:0004040 | amidase activity(GO:0004040) |
| 0.2 | 1.1 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.2 | 1.4 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.2 | 0.8 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972) |
| 0.2 | 2.2 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
| 0.2 | 0.2 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 0.8 | GO:0004080 | biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271) |
| 0.2 | 2.4 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.2 | 2.4 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.2 | 3.2 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.2 | 6.2 | GO:0033558 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
| 0.2 | 1.0 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.2 | 1.2 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.2 | 0.7 | GO:0061513 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 0.2 | 1.9 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 1.8 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.2 | 3.6 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.2 | 5.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.2 | 12.1 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.2 | 8.3 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.2 | 0.5 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.1 | 1.6 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.1 | 0.1 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 0.1 | 1.0 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 1.0 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.1 | 2.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 0.3 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.1 | 18.3 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 0.9 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.1 | 1.6 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.1 | 1.7 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 2.7 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 0.6 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.1 | 2.6 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.1 | 3.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 0.4 | GO:0002046 | opsin binding(GO:0002046) |
| 0.1 | 0.7 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.1 | 5.7 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.1 | 29.0 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 9.8 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 23.0 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 0.7 | GO:0004331 | fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) phosphofructokinase activity(GO:0008443) |
| 0.1 | 2.6 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 2.0 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.1 | 3.0 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.7 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.1 | 3.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 0.7 | GO:0019841 | retinol binding(GO:0019841) |
| 0.1 | 1.7 | GO:0043492 | ATPase activity, coupled to movement of substances(GO:0043492) |
| 0.1 | 0.4 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 1.8 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.1 | 21.7 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.1 | 1.8 | GO:0042805 | actinin binding(GO:0042805) |
| 0.1 | 7.2 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.1 | 12.9 | GO:0016887 | ATPase activity(GO:0016887) |
| 0.1 | 37.6 | GO:0008134 | transcription factor binding(GO:0008134) |
| 0.1 | 0.3 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.1 | 1.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 44.4 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.1 | 3.6 | GO:0019239 | deaminase activity(GO:0019239) |
| 0.1 | 25.0 | GO:0046873 | metal ion transmembrane transporter activity(GO:0046873) |
| 0.1 | 0.7 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.1 | 1.1 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
| 0.1 | 11.3 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.1 | 0.6 | GO:0051184 | cofactor transporter activity(GO:0051184) |
| 0.1 | 0.3 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.1 | 1.1 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 76.3 | GO:0003723 | RNA binding(GO:0003723) |
| 0.1 | 0.7 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.1 | 67.3 | GO:0042802 | identical protein binding(GO:0042802) |
| 0.1 | 4.5 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.1 | 2.8 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 0.6 | GO:0008865 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.1 | 0.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 0.1 | GO:0032090 | Pyrin domain binding(GO:0032090) |
| 0.1 | 0.1 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.1 | 1.4 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 0.5 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.0 | 0.1 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.0 | 0.7 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 0.7 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 1.5 | GO:0005319 | lipid transporter activity(GO:0005319) |
| 0.0 | 0.2 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.0 | 0.1 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.2 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 0.7 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.1 | GO:0009374 | biotin binding(GO:0009374) |
| 0.0 | 0.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.9 | 104.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 3.6 | 42.9 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 3.1 | 174.1 | PID AURORA A PATHWAY | Aurora A signaling |
| 2.4 | 72.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 2.3 | 66.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 1.4 | 39.3 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 1.4 | 30.7 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 1.3 | 75.3 | PID ATR PATHWAY | ATR signaling pathway |
| 1.2 | 65.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 1.1 | 47.4 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 1.1 | 21.1 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 1.0 | 35.8 | PID MYC PATHWAY | C-MYC pathway |
| 1.0 | 20.1 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.9 | 18.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.9 | 53.5 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.9 | 37.8 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.9 | 23.4 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.9 | 24.2 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.8 | 30.5 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.7 | 7.9 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.6 | 57.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.6 | 28.3 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.6 | 15.9 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.6 | 48.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.6 | 12.5 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.6 | 5.9 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.6 | 25.5 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.6 | 10.5 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.5 | 13.1 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.5 | 17.5 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.5 | 4.5 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.5 | 9.2 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.5 | 8.0 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.5 | 10.8 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.4 | 18.5 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.4 | 9.0 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.4 | 21.7 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.4 | 14.4 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.4 | 4.4 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.4 | 1.1 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.4 | 29.3 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.3 | 18.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.3 | 0.7 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.3 | 24.3 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.3 | 20.6 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.3 | 4.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.3 | 4.4 | PID ATM PATHWAY | ATM pathway |
| 0.3 | 2.8 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.3 | 2.7 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.3 | 11.4 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.3 | 3.1 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.3 | 14.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.2 | 3.7 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.2 | 10.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.2 | 8.3 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.2 | 2.0 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.2 | 1.0 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.2 | 3.2 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.2 | 8.2 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.2 | 3.8 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.2 | 5.0 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 2.5 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.1 | 0.8 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.1 | 5.8 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.1 | 3.7 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 25.9 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 9.8 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 1.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 2.1 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.1 | 1.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 0.9 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.1 | 0.8 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 14.5 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.7 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 7.6 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.9 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 1.0 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.9 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.5 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.2 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.0 | 0.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.0 | 84.4 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 4.2 | 271.6 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 3.9 | 96.8 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 3.4 | 89.6 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 3.4 | 151.2 | REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX | Genes involved in Formation of the HIV-1 Early Elongation Complex |
| 3.2 | 174.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 2.9 | 52.9 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 2.9 | 81.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 2.9 | 42.9 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 2.9 | 54.2 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 2.7 | 159.8 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 2.6 | 80.5 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 2.5 | 27.7 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 2.5 | 39.6 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 2.4 | 100.4 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 2.4 | 26.9 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 2.4 | 39.1 | REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA | Genes involved in Processing of Capped Intronless Pre-mRNA |
| 2.4 | 43.6 | REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
| 2.3 | 44.1 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 2.2 | 32.5 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 2.1 | 22.9 | REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX | Genes involved in CDT1 association with the CDC6:ORC:origin complex |
| 2.0 | 164.3 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 1.9 | 9.4 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 1.8 | 30.9 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 1.8 | 54.2 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 1.8 | 30.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 1.7 | 93.3 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 1.7 | 8.5 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 1.7 | 35.3 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 1.6 | 28.4 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 1.5 | 24.6 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 1.5 | 34.7 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 1.4 | 12.4 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 1.3 | 30.5 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 1.3 | 15.4 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 1.3 | 45.3 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 1.2 | 25.7 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 1.1 | 16.0 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 1.1 | 25.8 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 1.1 | 16.0 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 1.0 | 18.9 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 1.0 | 27.6 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 1.0 | 178.1 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 1.0 | 2.0 | REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 |
| 1.0 | 24.2 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.9 | 22.3 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.9 | 19.3 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.9 | 16.4 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.8 | 13.4 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.8 | 18.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.8 | 39.1 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.8 | 19.0 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.8 | 16.0 | REACTOME SIGNALING BY WNT | Genes involved in Signaling by Wnt |
| 0.7 | 6.0 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.7 | 16.0 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.7 | 6.4 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.7 | 16.1 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.7 | 41.6 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.7 | 22.6 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.7 | 12.8 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.7 | 14.5 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.6 | 7.0 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.6 | 15.7 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.6 | 4.5 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.5 | 8.7 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.5 | 22.8 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.5 | 1.1 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.5 | 1.5 | REACTOME G PROTEIN BETA GAMMA SIGNALLING | Genes involved in G-protein beta:gamma signalling |
| 0.5 | 5.7 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.5 | 5.6 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.5 | 14.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.5 | 9.8 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.4 | 16.5 | REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
| 0.4 | 26.2 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.4 | 18.4 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.4 | 4.9 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.4 | 13.0 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.4 | 31.1 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.4 | 7.4 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
| 0.4 | 3.1 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.4 | 1.5 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.3 | 2.2 | REACTOME RNA POL II PRE TRANSCRIPTION EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
| 0.3 | 8.1 | REACTOME GAP JUNCTION TRAFFICKING | Genes involved in Gap junction trafficking |
| 0.3 | 3.4 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.3 | 5.2 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 0.3 | 27.8 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.3 | 34.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.3 | 7.6 | REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | Genes involved in GRB2 events in ERBB2 signaling |
| 0.3 | 3.6 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.3 | 4.3 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.3 | 3.3 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.2 | 2.5 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.2 | 15.8 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.2 | 4.7 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.2 | 4.9 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.2 | 1.8 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.2 | 3.1 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.2 | 14.8 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.2 | 3.4 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.2 | 5.8 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.2 | 4.4 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.2 | 7.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 6.8 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.2 | 4.5 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.2 | 2.6 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.2 | 3.0 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.2 | 3.1 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.2 | 4.5 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.2 | 2.0 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.2 | 3.6 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 1.8 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 1.6 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.1 | 4.7 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 1.6 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 1.3 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.1 | 5.1 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.1 | 1.3 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.1 | 1.6 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 1.3 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 3.4 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 1.9 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 0.6 | REACTOME RNA POL III TRANSCRIPTION | Genes involved in RNA Polymerase III Transcription |
| 0.1 | 1.1 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 0.4 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 0.7 | REACTOME PURINE METABOLISM | Genes involved in Purine metabolism |
| 0.1 | 1.4 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.1 | 1.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 2.3 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 1.5 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.9 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 1.9 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 2.1 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.9 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.0 | 0.3 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 0.1 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |