Project
GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for FIGLA
Z-value: 1.10
Motif logo
Transcription factors associated with FIGLA
Network of associatons between targets according to the STRING database.
First level regulatory network of FIGLA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 53.6 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 5.7 | 51.4 | GO:0031536 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536) |
| 0.7 | 48.4 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 1.1 | 46.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 5.2 | 31.3 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 0.2 | 31.3 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
| 0.2 | 25.2 | GO:0031424 | keratinization(GO:0031424) |
| 1.7 | 22.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 3.7 | 18.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.4 | 18.4 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 64.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 61.9 | GO:0005615 | extracellular space(GO:0005615) |
| 3.9 | 31.3 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.1 | 29.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 28.9 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 28.3 | GO:0005815 | microtubule organizing center(GO:0005815) |
| 0.0 | 24.8 | GO:0005730 | nucleolus(GO:0005730) |
| 0.3 | 24.1 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 1.7 | 22.1 | GO:0042555 | MCM complex(GO:0042555) |
| 0.5 | 21.8 | GO:0045095 | keratin filament(GO:0045095) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 84.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 7.7 | 53.6 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.1 | 36.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 28.2 | GO:0005525 | GTP binding(GO:0005525) |
| 0.4 | 22.7 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.4 | 22.1 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.7 | 20.0 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.3 | 19.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 4.6 | 18.5 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 17.3 | GO:0005179 | hormone activity(GO:0005179) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 72.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.7 | 34.4 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.4 | 28.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.4 | 16.9 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.3 | 14.9 | PID ATR PATHWAY | ATR signaling pathway |
| 0.2 | 13.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.2 | 11.9 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.3 | 10.6 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.2 | 9.5 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.1 | 8.1 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 77.3 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.9 | 36.7 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.3 | 22.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 1.5 | 22.1 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 1.0 | 19.9 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.3 | 19.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 1.2 | 18.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.4 | 16.9 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 16.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 15.1 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |