GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
FOXC1 Links Ensembl NCBI GeneCards UniProt	ENSG00000054598.9	FOXC1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXC1	hg38_v1_chr6_+_1609890_1609932	0.11	9.1e-02	Click!

View svg image
View png image

Promoter	Score	Transcript	Gene	Gene Info
chr17_-_39607876 Show fit	25.79	ENST00000302584.5	NEUROD2 Links Ensembl NCBI GeneCards UniProt Show fit	neuronal differentiation 2
chr4_-_101346842 Show fit	20.22	ENST00000507176.5	PPP3CA Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr13_-_35855627 Show fit	14.19	ENST00000379893.5	DCLK1 Links Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr2_-_2326210 Show fit	12.71	ENST00000647755.1	MYT1L Links Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr16_+_7303245 Show fit	12.47	ENST00000674626.1	RBFOX1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr19_-_36032799 Show fit	11.37	ENST00000592017.5 ENST00000360535.9	CLIP3 Links Ensembl NCBI GeneCards UniProt Show fit	CAP-Gly domain containing linker protein 3
chr2_-_2326378 Show fit	10.67	ENST00000647618.1	MYT1L Links Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr16_+_6019585 Show fit	10.58	ENST00000547372.5	RBFOX1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr4_-_101347327 Show fit	10.52	ENST00000394853.8	PPP3CA Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr1_+_204870831 Show fit	9.76	ENST00000404076.5 ENST00000539706.6	NFASC Links Ensembl NCBI GeneCards UniProt Show fit	neurofascin
chr4_-_101347492 Show fit	9.71	ENST00000394854.8	PPP3CA Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr13_-_35855758 Show fit	9.39	ENST00000615680.4	DCLK1 Links Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr4_-_101347471 Show fit	9.22	ENST00000323055.10 ENST00000512215.5	PPP3CA Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr2_+_165239432 Show fit	9.18	ENST00000636071.2 ENST00000636985.2	SCN2A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 2
chr10_+_93758063 Show fit	8.91	ENST00000627699.1 ENST00000371413.4	LGI1 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich glioma inactivated 1
chr16_+_6019016 Show fit	8.29	ENST00000550418.6	RBFOX1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr2_+_172860038 Show fit	8.13	ENST00000538974.5 ENST00000540783.5	RAPGEF4 Links Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 4
chr2_-_71227055 Show fit	8.09	ENST00000244221.9	PAIP2B Links Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein interacting protein 2B
chr12_+_10212867 Show fit	8.03	ENST00000545047.5 ENST00000266458.10 ENST00000629504.1 ENST00000543602.5 ENST00000545887.1	GABARAPL1 Links Ensembl NCBI GeneCards UniProt Show fit	GABA type A receptor associated protein like 1
chr10_+_93757831 Show fit	7.98	ENST00000629035.2	LGI1 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich glioma inactivated 1
chr11_-_6419051 Show fit	7.79	ENST00000299402.10 ENST00000532020.2 ENST00000609360.6 ENST00000389906.6	APBB1 Links Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein binding family B member 1
chr16_+_6019071 Show fit	7.77	ENST00000547605.5 ENST00000553186.5	RBFOX1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr4_-_152382522 Show fit	7.53	ENST00000296555.11	FBXW7 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 7
chr11_-_6419394 Show fit	7.34	ENST00000311051.7	APBB1 Links Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein binding family B member 1
chr5_-_24644968 Show fit	7.05	ENST00000264463.8	CDH10 Links Ensembl NCBI GeneCards UniProt Show fit	cadherin 10
chr2_+_165239388 Show fit	6.95	ENST00000424833.5 ENST00000375437.7 ENST00000631182.3	SCN2A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 2
chr10_+_93757857 Show fit	6.87	ENST00000478763.2 ENST00000371418.9 ENST00000630184.2 ENST00000630047.2 ENST00000637689.1	LGI1 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich glioma inactivated 1
chr2_+_172821575 Show fit	6.87	ENST00000397087.7	RAPGEF4 Links Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 4
chr7_+_86643902 Show fit	6.70	ENST00000361669.7	GRM3 Links Ensembl NCBI GeneCards UniProt Show fit	glutamate metabotropic receptor 3
chr6_-_152168349 Show fit	6.68	ENST00000539504.5	SYNE1 Links Ensembl NCBI GeneCards UniProt Show fit	spectrin repeat containing nuclear envelope protein 1
chr6_-_152168291 Show fit	6.67	ENST00000354674.5	SYNE1 Links Ensembl NCBI GeneCards UniProt Show fit	spectrin repeat containing nuclear envelope protein 1
chr10_-_67838173 Show fit	6.62	ENST00000225171.7	DNAJC12 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C12
chr2_-_223602284 Show fit	6.33	ENST00000421386.1 ENST00000305409.3 ENST00000433889.1	SCG2 Links Ensembl NCBI GeneCards UniProt Show fit	secretogranin II
chr18_-_55635948 Show fit	6.15	ENST00000565124.4 ENST00000398339.5	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr3_-_127736329 Show fit	6.13	ENST00000398101.7	MGLL Links Ensembl NCBI GeneCards UniProt Show fit	monoglyceride lipase
chr5_-_146922515 Show fit	5.98	ENST00000508545.6	PPP2R2B Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit Bbeta
chr6_-_56851888 Show fit	5.93	ENST00000312431.10 ENST00000520645.5	DST Links Ensembl NCBI GeneCards UniProt Show fit	dystonin
chr13_+_32031706 Show fit	5.92	ENST00000542859.6	FRY Links Ensembl NCBI GeneCards UniProt Show fit	FRY microtubule binding protein
chr11_-_790062 Show fit	5.55	ENST00000330106.5	CEND1 Links Ensembl NCBI GeneCards UniProt Show fit	cell cycle exit and neuronal differentiation 1
chr5_-_131796921 Show fit	5.52	ENST00000307968.11 ENST00000307954.12	FNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	folliculin interacting protein 1
chr4_+_70721953 Show fit	5.38	ENST00000381006.8 ENST00000226328.8	RUFY3 Links Ensembl NCBI GeneCards UniProt Show fit	RUN and FYVE domain containing 3
chr17_+_43211835 Show fit	5.28	ENST00000588693.5 ENST00000588659.5 ENST00000541594.5 ENST00000536052.5 ENST00000612339.4	TMEM106A Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 106A
chr10_-_121596117 Show fit	5.21	ENST00000351936.11	FGFR2 Links Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor receptor 2
chr16_+_56191476 Show fit	5.16	ENST00000262493.12	GNAO1 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha o1
chr18_+_31591869 Show fit	4.96	ENST00000237014.8	TTR Links Ensembl NCBI GeneCards UniProt Show fit	transthyretin
chr3_-_195583931 Show fit	4.94	ENST00000343267.8 ENST00000421243.5 ENST00000453131.1	APOD Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein D
chr5_-_131797030 Show fit	4.85	ENST00000615660.4	FNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	folliculin interacting protein 1
chr2_+_172928165 Show fit	4.83	ENST00000535187.5	RAPGEF4 Links Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 4
chr1_+_50105666 Show fit	4.65	ENST00000651347.1	ELAVL4 Links Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 4
chr19_+_708903 Show fit	4.57	ENST00000338448.10 ENST00000264560.11	PALM Links Ensembl NCBI GeneCards UniProt Show fit	paralemmin
chr5_-_116536458 Show fit	4.48	ENST00000510263.5	SEMA6A Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6A
chr11_+_112961247 Show fit	4.42	ENST00000621518.4 ENST00000618266.4 ENST00000615112.4 ENST00000615285.4 ENST00000619839.4 ENST00000401611.6 ENST00000621128.4	NCAM1 Links Ensembl NCBI GeneCards UniProt Show fit	neural cell adhesion molecule 1
chr5_-_111756245 Show fit	4.14	ENST00000447165.6	NREP Links Ensembl NCBI GeneCards UniProt Show fit	neuronal regeneration related protein
chr3_-_114624193 Show fit	4.11	ENST00000481632.5	ZBTB20 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr2_-_72147819 Show fit	4.10	ENST00000001146.7 ENST00000546307.5 ENST00000474509.1	CYP26B1 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 26 subfamily B member 1
chr4_-_98657635 Show fit	4.04	ENST00000515287.5 ENST00000511651.5 ENST00000505184.5	TSPAN5 Links Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 5
chr6_+_101398788 Show fit	4.02	ENST00000369138.5 ENST00000413795.5 ENST00000358361.7	GRIK2 Links Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor kainate type subunit 2
chr7_-_13988863 Show fit	4.00	ENST00000405358.8	ETV1 Links Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chr1_-_160523204 Show fit	3.85	ENST00000368055.1 ENST00000368057.8 ENST00000368059.7	SLAMF6 Links Ensembl NCBI GeneCards UniProt Show fit	SLAM family member 6
chr1_+_174877430 Show fit	3.71	ENST00000392064.6	RABGAP1L Links Ensembl NCBI GeneCards UniProt Show fit	RAB GTPase activating protein 1 like
chr8_-_133297092 Show fit	3.62	ENST00000522890.5 ENST00000675983.1 ENST00000518176.5 ENST00000323851.13 ENST00000522476.5 ENST00000518066.5 ENST00000521544.5 ENST00000674605.1 ENST00000518480.5 ENST00000523892.5	NDRG1 Links Ensembl NCBI GeneCards UniProt Show fit	N-myc downstream regulated 1
chr4_+_85475131 Show fit	3.49	ENST00000395184.6	ARHGAP24 Links Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 24
chr11_+_93746433 Show fit	3.47	ENST00000526335.1	C11orf54 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 54
chr15_-_29822418 Show fit	3.43	ENST00000614355.5 ENST00000495972.6 ENST00000346128.10	TJP1 Links Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 1
chr13_+_35476740 Show fit	3.40	ENST00000537702.5	NBEA Links Ensembl NCBI GeneCards UniProt Show fit	neurobeachin
chr1_+_226223618 Show fit	3.35	ENST00000542034.5 ENST00000366810.6	MIXL1 Links Ensembl NCBI GeneCards UniProt Show fit	Mix paired-like homeobox
chr5_+_162067458 Show fit	3.22	ENST00000639975.1 ENST00000639111.2 ENST00000639683.1	GABRG2 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chr18_-_55403682 Show fit	3.20	ENST00000564228.5 ENST00000630828.2	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr13_+_31945826 Show fit	3.20	ENST00000647500.1	FRY Links Ensembl NCBI GeneCards UniProt Show fit	FRY microtubule binding protein
chr12_-_98644733 Show fit	3.13	ENST00000299157.5 ENST00000393042.3	IKBIP Links Ensembl NCBI GeneCards UniProt Show fit	IKBKB interacting protein
chr2_+_209653171 Show fit	3.09	ENST00000447185.5	MAP2 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr11_+_114059755 Show fit	3.08	ENST00000684295.1	ZBTB16 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 16
chr10_+_80413817 Show fit	3.03	ENST00000372187.9	PRXL2A Links Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin like 2A
chr5_+_162068031 Show fit	3.01	ENST00000356592.8	GABRG2 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chr1_-_151459471 Show fit	2.96	ENST00000271715.7	POGZ Links Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with ZNF domain
chr15_+_75347030 Show fit	2.88	ENST00000566313.5 ENST00000355059.9 ENST00000568059.1 ENST00000568881.1	NEIL1 Links Ensembl NCBI GeneCards UniProt Show fit	nei like DNA glycosylase 1
chr5_+_162067500 Show fit	2.87	ENST00000639384.1 ENST00000640985.1 ENST00000638772.1	GABRG2 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chr18_+_62715526 Show fit	2.64	ENST00000262719.10	PHLPP1 Links Ensembl NCBI GeneCards UniProt Show fit	PH domain and leucine rich repeat protein phosphatase 1
chr2_-_112255015 Show fit	2.64	ENST00000615791.1 ENST00000409573.7 ENST00000272570.9	ZC3H8 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 8
chr11_+_114060204 Show fit	2.61	ENST00000683318.1	ZBTB16 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 16
chr15_-_55365231 Show fit	2.58	ENST00000568543.1	CCPG1 Links Ensembl NCBI GeneCards UniProt Show fit	cell cycle progression 1
chr11_+_73308237 Show fit	2.54	ENST00000263674.4	ARHGEF17 Links Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 17
chr3_+_40309678 Show fit	2.50	ENST00000232905.4	EIF1B Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1B
chr10_+_91162958 Show fit	2.49	ENST00000614189.4	PCGF5 Links Ensembl NCBI GeneCards UniProt Show fit	polycomb group ring finger 5
chr18_+_34493428 Show fit	2.37	ENST00000682483.1	DTNA Links Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin alpha
chr5_+_162067764 Show fit	2.33	ENST00000639213.2 ENST00000414552.6	GABRG2 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chrX_+_54920796 Show fit	2.25	ENST00000442098.5 ENST00000430420.5 ENST00000453081.5 ENST00000319167.12 ENST00000622017.4 ENST00000375022.8 ENST00000399736.5 ENST00000440072.5 ENST00000173898.12 ENST00000431115.5 ENST00000440759.5 ENST00000375041.6	TRO Links Ensembl NCBI GeneCards UniProt Show fit	trophinin
chr19_+_3880647 Show fit	2.23	ENST00000450849.7	ATCAY Links Ensembl NCBI GeneCards UniProt Show fit	ATCAY kinesin light chain interacting caytaxin
chr10_+_110225955 Show fit	2.14	ENST00000239007.11	MXI1 Links Ensembl NCBI GeneCards UniProt Show fit	MAX interactor 1, dimerization protein
chr4_+_20251896 Show fit	2.03	ENST00000504154.6	SLIT2 Links Ensembl NCBI GeneCards UniProt Show fit	slit guidance ligand 2
chr18_+_34493386 Show fit	2.02	ENST00000679936.1	DTNA Links Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin alpha
chr10_+_52314272 Show fit	2.01	ENST00000373970.4	DKK1 Links Ensembl NCBI GeneCards UniProt Show fit	dickkopf WNT signaling pathway inhibitor 1
chr7_-_95434951 Show fit	2.01	ENST00000478801.5 ENST00000469926.5 ENST00000493290.5 ENST00000222572.8 ENST00000633531.1 ENST00000490778.5 ENST00000433091.6	PON2 Links Ensembl NCBI GeneCards UniProt Show fit	paraoxonase 2
chr15_+_75347610 Show fit	2.01	ENST00000564784.5 ENST00000569035.5	NEIL1 Links Ensembl NCBI GeneCards UniProt Show fit	nei like DNA glycosylase 1
chr5_+_162067858 Show fit	1.99	ENST00000361925.9	GABRG2 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chr7_-_95435329 Show fit	1.99	ENST00000633192.1	PON2 Links Ensembl NCBI GeneCards UniProt Show fit	paraoxonase 2
chr2_+_219178266 Show fit	1.98	ENST00000430297.7	RETREG2 Links Ensembl NCBI GeneCards UniProt Show fit	reticulophagy regulator family member 2
chr12_-_121669646 Show fit	1.97	ENST00000355329.7	MORN3 Links Ensembl NCBI GeneCards UniProt Show fit	MORN repeat containing 3
chr11_+_27055215 Show fit	1.93	ENST00000525090.1	BBOX1 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-butyrobetaine hydroxylase 1
chr2_-_8837589 Show fit	1.91	ENST00000319688.5 ENST00000489024.5 ENST00000256707.8 ENST00000473731.5	KIDINS220 Links Ensembl NCBI GeneCards UniProt Show fit	kinase D interacting substrate 220
chr2_+_27663441 Show fit	1.85	ENST00000326019.10 ENST00000613058.4	SLC4A1AP Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 member 1 adaptor protein
chr3_+_46407251 Show fit	1.82	ENST00000399036.4	CCRL2 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine receptor like 2
chr11_+_46617521 Show fit	1.79	ENST00000580238.5 ENST00000581416.5 ENST00000529655.5 ENST00000533325.5 ENST00000683050.1 ENST00000581438.5 ENST00000583249.5 ENST00000530500.5 ENST00000526508.5 ENST00000578626.5 ENST00000577256.5 ENST00000524625.5 ENST00000582547.5 ENST00000359513.8 ENST00000528494.5	ATG13 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 13
chr20_+_45881218 Show fit	1.79	ENST00000372523.1	ZSWIM1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger SWIM-type containing 1
chr2_-_27663817 Show fit	1.78	ENST00000404798.6	SUPT7L Links Ensembl NCBI GeneCards UniProt Show fit	SPT7 like, STAGA complex subunit gamma
chr8_-_19682576 Show fit	1.71	ENST00000332246.10	CSGALNACT1 Links Ensembl NCBI GeneCards UniProt Show fit	chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr6_+_138773747 Show fit	1.65	ENST00000617445.5	CCDC28A Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 28A
chr7_-_139777774 Show fit	1.63	ENST00000428878.6	HIPK2 Links Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 2
chr1_+_220528112 Show fit	1.63	ENST00000366917.6 ENST00000402574.5 ENST00000611084.4 ENST00000366918.8	MARK1 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule affinity regulating kinase 1
chrX_-_139708190 Show fit	1.60	ENST00000414978.5 ENST00000519895.5	MCF2 Links Ensembl NCBI GeneCards UniProt Show fit	MCF.2 cell line derived transforming sequence
chr2_-_27663594 Show fit	1.60	ENST00000337768.10 ENST00000405491.5 ENST00000464789.2 ENST00000406540.5	SUPT7L Links Ensembl NCBI GeneCards UniProt Show fit	SPT7 like, STAGA complex subunit gamma
chr2_+_27663880 Show fit	1.59	ENST00000618046.4 ENST00000613517.4	SLC4A1AP Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 member 1 adaptor protein
chr18_-_28177016 Show fit	1.55	ENST00000430882.6	CDH2 Links Ensembl NCBI GeneCards UniProt Show fit	cadherin 2
chr15_-_58279245 Show fit	1.54	ENST00000558231.5	ALDH1A2 Links Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family member A2
chr4_-_185775271 Show fit	1.54	ENST00000430503.5 ENST00000319454.10 ENST00000450341.5	SORBS2 Links Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr6_+_32154131 Show fit	1.54	ENST00000375143.6 ENST00000324816.11 ENST00000424499.1	PPT2 Links Ensembl NCBI GeneCards UniProt Show fit	palmitoyl-protein thioesterase 2
chr20_-_18467023 Show fit	1.54	ENST00000262547.9	DZANK1 Links Ensembl NCBI GeneCards UniProt Show fit	double zinc ribbon and ankyrin repeat domains 1
chr12_+_55019967 Show fit	1.52	ENST00000242994.4	NEUROD4 Links Ensembl NCBI GeneCards UniProt Show fit	neuronal differentiation 4
chr3_+_46407558 Show fit	1.52	ENST00000357392.4 ENST00000400880.3 ENST00000433848.1	CCRL2 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine receptor like 2
chr22_-_38302990 Show fit	1.52	ENST00000612795.2 ENST00000451964.5	CSNK1E Links Ensembl NCBI GeneCards UniProt Show fit	casein kinase 1 epsilon
chr6_-_99994173 Show fit	1.50	ENST00000281806.7 ENST00000369212.2	MCHR2 Links Ensembl NCBI GeneCards UniProt Show fit	melanin concentrating hormone receptor 2
chr1_-_151459169 Show fit	1.49	ENST00000368863.6 ENST00000409503.5 ENST00000491586.5 ENST00000533351.5	POGZ Links Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with ZNF domain
chr12_+_851415 Show fit	1.43	ENST00000675631.1	WNK1 Links Ensembl NCBI GeneCards UniProt Show fit	WNK lysine deficient protein kinase 1
chr8_+_119067239 Show fit	1.43	ENST00000332843.3	COLEC10 Links Ensembl NCBI GeneCards UniProt Show fit	collectin subfamily member 10
chrX_-_6535118 Show fit	1.40	ENST00000381089.7 ENST00000612369.4 ENST00000398729.1	VCX3A Links Ensembl NCBI GeneCards UniProt Show fit	variable charge X-linked 3A
chr10_+_112950757 Show fit	1.38	ENST00000629706.2 ENST00000346198.5	TCF7L2 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr16_+_31117656 Show fit	1.36	ENST00000219797.9 ENST00000448516.6	KAT8 Links Ensembl NCBI GeneCards UniProt Show fit	lysine acetyltransferase 8
chr3_-_187745460 Show fit	1.30	ENST00000406870.7	BCL6 Links Ensembl NCBI GeneCards UniProt Show fit	BCL6 transcription repressor
chr4_-_73620391 Show fit	1.29	ENST00000395777.6 ENST00000307439.10	RASSF6 Links Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 6
chr1_+_25338294 Show fit	1.28	ENST00000374358.5	TMEM50A Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 50A
chr3_-_114759115 Show fit	1.21	ENST00000471418.5	ZBTB20 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr8_-_140921188 Show fit	1.19	ENST00000517887.5	PTK2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2
chr4_-_73620629 Show fit	1.18	ENST00000342081.7	RASSF6 Links Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 6
chr6_+_32154010 Show fit	1.14	ENST00000375137.6	PPT2 Links Ensembl NCBI GeneCards UniProt Show fit	palmitoyl-protein thioesterase 2
chr3_-_48440022 Show fit	1.09	ENST00000447018.5 ENST00000442740.1 ENST00000412398.6 ENST00000395694.7	CCDC51 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 51
chr19_-_42427379 Show fit	1.01	ENST00000244289.9	LIPE Links Ensembl NCBI GeneCards UniProt Show fit	lipase E, hormone sensitive type
chr15_-_74366178 Show fit	1.00	ENST00000450547.1 ENST00000358632.8	CYP11A1 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 11 subfamily A member 1
chr10_+_69801874 Show fit	0.98	ENST00000357811.8	COL13A1 Links Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr17_-_29176752 Show fit	0.95	ENST00000533112.5	MYO18A Links Ensembl NCBI GeneCards UniProt Show fit	myosin XVIIIA
chr10_-_95441015 Show fit	0.95	ENST00000371241.5 ENST00000354106.7 ENST00000371239.5 ENST00000361941.7 ENST00000277982.9 ENST00000371245.7	SORBS1 Links Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 1
chr3_-_114758940 Show fit	0.94	ENST00000464560.5	ZBTB20 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr5_-_146878595 Show fit	0.87	ENST00000394409.7	PPP2R2B Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit Bbeta
chrX_-_108736556 Show fit	0.83	ENST00000372129.4	IRS4 Links Ensembl NCBI GeneCards UniProt Show fit	insulin receptor substrate 4
chr8_-_71362054 Show fit	0.82	ENST00000340726.8	EYA1 Links Ensembl NCBI GeneCards UniProt Show fit	EYA transcriptional coactivator and phosphatase 1
chr17_-_50468871 Show fit	0.81	ENST00000508540.6 ENST00000258969.4	CHAD Links Ensembl NCBI GeneCards UniProt Show fit	chondroadherin
chrX_+_71215156 Show fit	0.80	ENST00000374029.2 ENST00000675209.1 ENST00000647424.1 ENST00000675368.1 ENST00000675609.1 ENST00000646835.1 ENST00000447581.2	GJB1 Links Ensembl NCBI GeneCards UniProt Show fit	gap junction protein beta 1
chr2_+_44275473 Show fit	0.79	ENST00000260649.11	SLC3A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 3 member 1
chr2_+_113127588 Show fit	0.78	ENST00000409930.4	IL1RN Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor antagonist
chr19_-_40413364 Show fit	0.76	ENST00000291825.11 ENST00000324001.8	PRX Links Ensembl NCBI GeneCards UniProt Show fit	periaxin
chrX_-_8171267 Show fit	0.76	ENST00000317103.5	VCX2 Links Ensembl NCBI GeneCards UniProt Show fit	variable charge X-linked 2
chr6_+_10528326 Show fit	0.74	ENST00000379597.7	GCNT2 Links Ensembl NCBI GeneCards UniProt Show fit	glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr11_-_78341876 Show fit	0.73	ENST00000340149.6	GAB2 Links Ensembl NCBI GeneCards UniProt Show fit	GRB2 associated binding protein 2
chr6_-_110815408 Show fit	0.72	ENST00000368911.8	CDK19 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 19
chr4_-_163613505 Show fit	0.72	ENST00000339875.9	MARCHF1 Links Ensembl NCBI GeneCards UniProt Show fit	membrane associated ring-CH-type finger 1
chr14_+_36657560 Show fit	0.70	ENST00000402703.6	PAX9 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 9
chr2_-_219178103 Show fit	0.70	ENST00000409789.5	CNPPD1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin Pas1/PHO80 domain containing 1
chr2_-_144516154 Show fit	0.70	ENST00000637304.1	ZEB2 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger E-box binding homeobox 2
chr3_+_178419123 Show fit	0.70	ENST00000614557.1 ENST00000455307.5 ENST00000436432.1	ENSG00000275163.1 Links Ensembl NCBI GeneCards UniProt Show fit LINC01014 Links Ensembl NCBI GeneCards UniProt Show fit	potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript) long intergenic non-protein coding RNA 1014
chr11_-_108593738 Show fit	0.67	ENST00000525344.5 ENST00000265843.9	EXPH5 Links Ensembl NCBI GeneCards UniProt Show fit	exophilin 5
chr20_+_38317627 Show fit	0.65	ENST00000417318.3	BPI Links Ensembl NCBI GeneCards UniProt Show fit	bactericidal permeability increasing protein
chr12_-_10098977 Show fit	0.62	ENST00000315330.8 ENST00000457018.6	CLEC1A Links Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 1 member A
chr8_-_92095215 Show fit	0.61	ENST00000360348.6 ENST00000520428.5 ENST00000518992.5 ENST00000520556.5 ENST00000518317.5 ENST00000521319.5 ENST00000521375.5 ENST00000518449.5 ENST00000613886.4	RUNX1T1 Links Ensembl NCBI GeneCards UniProt Show fit	RUNX1 partner transcriptional co-repressor 1
chr2_-_144516397 Show fit	0.53	ENST00000638128.1	ZEB2 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger E-box binding homeobox 2
chr7_-_13989658 Show fit	0.53	ENST00000430479.6 ENST00000433547.1 ENST00000405192.6	ETV1 Links Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chrX_+_22032301 Show fit	0.50	ENST00000379374.5	PHEX Links Ensembl NCBI GeneCards UniProt Show fit	phosphate regulating endopeptidase homolog X-linked
chr10_-_116273606 Show fit	0.47	ENST00000682743.1	GFRA1 Links Ensembl NCBI GeneCards UniProt Show fit	GDNF family receptor alpha 1
chr2_-_207165923 Show fit	0.42	ENST00000309446.11	KLF7 Links Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 7
chr21_-_32813695 Show fit	0.41	ENST00000479548.2 ENST00000490358.5	C21orf62 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 21 open reading frame 62
chr11_+_10456186 Show fit	0.39	ENST00000528723.5	AMPD3 Links Ensembl NCBI GeneCards UniProt Show fit	adenosine monophosphate deaminase 3
chr6_-_53061740 Show fit	0.38	ENST00000350082.10 ENST00000356971.3 ENST00000676107.1	CILK1 Links Ensembl NCBI GeneCards UniProt Show fit	ciliogenesis associated kinase 1
chr1_-_169734064 Show fit	0.36	ENST00000333360.12	SELE Links Ensembl NCBI GeneCards UniProt Show fit	selectin E
chr5_-_128339191 Show fit	0.36	ENST00000507835.5	FBN2 Links Ensembl NCBI GeneCards UniProt Show fit	fibrillin 2
chr6_-_32224060 Show fit	0.34	ENST00000375023.3	NOTCH4 Links Ensembl NCBI GeneCards UniProt Show fit	notch receptor 4
chr5_+_160009113 Show fit	0.32	ENST00000522793.5 ENST00000682719.1 ENST00000684137.1 ENST00000683219.1 ENST00000684018.1 ENST00000231238.10 ENST00000682131.1	TTC1 Links Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 1
chr12_+_59596010 Show fit	0.29	ENST00000547379.6 ENST00000552432.5	SLC16A7 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 7
chr5_+_143812161 Show fit	0.27	ENST00000289448.4	HMHB1 Links Ensembl NCBI GeneCards UniProt Show fit	histocompatibility minor HB-1
chr5_+_160187367 Show fit	0.27	ENST00000393980.8	FABP6 Links Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 6
chr17_-_27793716 Show fit	0.27	ENST00000646938.1	NOS2 Links Ensembl NCBI GeneCards UniProt Show fit	nitric oxide synthase 2
chr13_+_27251569 Show fit	0.25	ENST00000272274.8 ENST00000319826.8 ENST00000326092.8	RPL21 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L21
chr16_-_53703883 Show fit	0.24	ENST00000262135.9 ENST00000564374.5 ENST00000566096.5	RPGRIP1L Links Ensembl NCBI GeneCards UniProt Show fit	RPGRIP1 like
chr22_-_46263338 Show fit	0.23	ENST00000253255.7	PKDREJ Links Ensembl NCBI GeneCards UniProt Show fit	polycystin family receptor for egg jelly
chr6_+_20534441 Show fit	0.22	ENST00000274695.8 ENST00000613575.4	CDKAL1 Links Ensembl NCBI GeneCards UniProt Show fit	CDK5 regulatory subunit associated protein 1 like 1
chr2_-_206159410 Show fit	0.19	ENST00000457011.5 ENST00000440274.5 ENST00000432169.5 ENST00000233190.11	NDUFS1 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S1
chr19_-_4831689 Show fit	0.19	ENST00000248244.6	TICAM1 Links Ensembl NCBI GeneCards UniProt Show fit	toll like receptor adaptor molecule 1
chr5_-_56233287 Show fit	0.18	ENST00000513241.2 ENST00000341048.9	ANKRD55 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 55
chr11_-_46593948 Show fit	0.18	ENST00000533727.5 ENST00000534300.5 ENST00000683756.1 ENST00000528950.1 ENST00000526606.1	AMBRA1 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy and beclin 1 regulator 1
chr8_-_71361860 Show fit	0.17	ENST00000303824.11 ENST00000645451.1	EYA1 Links Ensembl NCBI GeneCards UniProt Show fit	EYA transcriptional coactivator and phosphatase 1
chr19_-_51751854 Show fit	0.16	ENST00000304748.5 ENST00000595042.5	FPR1 Links Ensembl NCBI GeneCards UniProt Show fit	formyl peptide receptor 1
chr15_+_67125707 Show fit	0.15	ENST00000540846.6	SMAD3 Links Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 3
chr19_-_5286163 Show fit	0.15	ENST00000592099.5 ENST00000588012.5 ENST00000262963.10 ENST00000587303.5 ENST00000590509.5	PTPRS Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type S
chr16_-_53703810 Show fit	0.14	ENST00000569716.1 ENST00000562588.5 ENST00000621565.5 ENST00000562230.5 ENST00000563746.5 ENST00000568653.7 ENST00000647211.2	RPGRIP1L Links Ensembl NCBI GeneCards UniProt Show fit	RPGRIP1 like
chr18_-_54959391 Show fit	0.13	ENST00000591504.6	CCDC68 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 68
chr14_-_92106535 Show fit	0.13	ENST00000526872.3 ENST00000532032.5 ENST00000506466.5 ENST00000554592.5 ENST00000555381.5 ENST00000553491.5 ENST00000556220.5 ENST00000557311.6 ENST00000617719.4 ENST00000554672.6 ENST00000644486.2 ENST00000502250.5 ENST00000503767.5	ATXN3 Links Ensembl NCBI GeneCards UniProt Show fit	ataxin 3
chr3_-_119559529 Show fit	0.12	ENST00000478182.5	CD80 Links Ensembl NCBI GeneCards UniProt Show fit	CD80 molecule
chr3_+_189631373 Show fit	0.12	ENST00000264731.8 ENST00000418709.6 ENST00000320472.9 ENST00000392460.7 ENST00000440651.6	TP63 Links Ensembl NCBI GeneCards UniProt Show fit	tumor protein p63
chr10_-_116272266 Show fit	0.10	ENST00000682489.1 ENST00000369236.5	GFRA1 Links Ensembl NCBI GeneCards UniProt Show fit	GDNF family receptor alpha 1
chr2_-_160200289 Show fit	0.10	ENST00000409872.1	ITGB6 Links Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 6

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
12.4	49.7	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
6.4	25.8	GO:2000297	negative regulation of synapse maturation(GO:2000297)
5.0	15.1	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
2.8	11.4	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
2.3	9.1	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
1.9	9.5	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
1.9	7.5	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.6	4.9	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.4	4.1	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.3	13.4	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.2	16.1	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
1.1	5.6	GO:0021699	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
1.1	9.8	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.9	5.7	GO:0051138	positive regulation of NK T cell differentiation(GO:0051138)
0.9	5.2	GO:0035602	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.7	3.4	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.7	6.1	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.7	2.0	GO:0071676	negative regulation of mononuclear cell migration(GO:0071676)
0.7	2.0	GO:0009996	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996)
0.7	3.3	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.7	5.9	GO:0008090	retrograde axonal transport(GO:0008090)
0.6	1.7	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.6	2.2	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763)
0.5	21.2	GO:0048665	neuron fate specification(GO:0048665)
0.5	8.0	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.5	2.6	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.5	6.3	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.5	24.8	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.5	39.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.5	13.4	GO:0071420	cellular response to histamine(GO:0071420)
0.4	4.9	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.4	6.7	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4	5.0	GO:0070327	thyroid hormone transport(GO:0070327)
0.4	1.9	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.4	1.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.4	1.4	GO:0023016	signal transduction by trans-phosphorylation(GO:0023016)
0.3	3.6	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.3	8.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.3	1.0	GO:1903028	positive regulation of opsonization(GO:1903028)
0.3	4.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3	2.6	GO:0002870	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.3	2.6	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3	6.9	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.3	0.8	GO:1900154	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.3	4.5	GO:0051382	kinetochore assembly(GO:0051382)
0.3	1.5	GO:0035881	amacrine cell differentiation(GO:0035881)
0.2	2.7	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.2	3.9	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.2	4.5	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.2	19.1	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.2	4.5	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2	1.9	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.2	1.6	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.2	1.6	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2	1.5	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2	3.4	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.2	1.0	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.1	1.2	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.1	5.4	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	4.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.5	GO:1990418	response to sodium phosphate(GO:1904383) response to insulin-like growth factor stimulus(GO:1990418)
0.1	0.7	GO:0036438	maintenance of lens transparency(GO:0036438)
0.1	5.2	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1	0.8	GO:0015811	L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.1	0.8	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1	21.9	GO:0050806	positive regulation of synaptic transmission(GO:0050806)
0.1	4.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	4.0	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	2.0	GO:0098780	response to mitochondrial depolarisation(GO:0098780)
0.1	0.8	GO:0015868	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1	0.9	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.1	3.0	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	1.4	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	0.9	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	3.1	GO:0010165	response to X-ray(GO:0010165)
0.1	0.7	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	3.1	GO:0021954	central nervous system neuron development(GO:0021954)
0.0	1.5	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.7	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0034163	negative regulation of interferon-alpha production(GO:0032687) regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0	1.0	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	7.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.3	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.0	0.1	GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0	0.7	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	1.0	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.3	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	3.1	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.4	GO:0060346	bone trabecula formation(GO:0060346)
0.0	2.5	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.3	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	1.0	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	4.4	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.4	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.2	GO:0032916	negative regulation of cardiac muscle adaptation(GO:0010616) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0	0.4	GO:0050901	leukocyte migration involved in inflammatory response(GO:0002523) leukocyte tethering or rolling(GO:0050901)
0.0	0.3	GO:0032310	positive regulation of guanylate cyclase activity(GO:0031284) prostaglandin secretion(GO:0032310)
0.0	1.5	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.6	GO:0042481	regulation of odontogenesis(GO:0042481)
0.0	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	1.6	GO:0030010	establishment of cell polarity(GO:0030010)
0.0	3.9	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.5	49.7	GO:0005955	calcineurin complex(GO:0005955)
2.0	9.8	GO:0097454	Schwann cell microvillus(GO:0097454)
1.7	15.1	GO:1990761	growth cone lamellipodium(GO:1990761)
1.2	5.9	GO:0031673	H zone(GO:0031673)
1.1	7.5	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.0	13.4	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.9	16.1	GO:0033270	paranode region of axon(GO:0033270)
0.7	2.6	GO:0035363	histone locus body(GO:0035363)
0.6	26.0	GO:0032590	dendrite membrane(GO:0032590)
0.4	3.1	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.3	1.0	GO:0005899	insulin receptor complex(GO:0005899)
0.3	6.3	GO:0031045	dense core granule(GO:0031045)
0.3	1.8	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.2	3.4	GO:0030914	STAGA complex(GO:0030914)
0.2	15.0	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	6.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.2	1.4	GO:0072487	MSL complex(GO:0072487)
0.2	5.4	GO:0071437	invadopodium(GO:0071437)
0.2	40.0	GO:0005802	trans-Golgi network(GO:0005802)
0.1	4.0	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	4.0	GO:0005921	gap junction(GO:0005921)
0.1	0.4	GO:0005879	axonemal microtubule(GO:0005879)
0.1	31.6	GO:0060076	excitatory synapse(GO:0060076)
0.1	5.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	6.6	GO:0016605	PML body(GO:0016605)
0.1	9.1	GO:0030427	site of polarized growth(GO:0030427)
0.0	1.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	5.6	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	1.1	GO:0005657	replication fork(GO:0005657)
0.0	2.5	GO:0031519	PcG protein complex(GO:0031519)
0.0	5.4	GO:0032993	protein-DNA complex(GO:0032993)
0.0	22.5	GO:0045202	synapse(GO:0045202)
0.0	4.1	GO:0030425	dendrite(GO:0030425)
0.0	4.5	GO:0030424	axon(GO:0030424)
0.0	3.7	GO:0005769	early endosome(GO:0005769)
0.0	2.0	GO:0031901	early endosome membrane(GO:0031901)
0.0	1.4	GO:0005901	caveola(GO:0005901)
0.0	0.2	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	1.9	GO:0005770	late endosome(GO:0005770)
0.0	1.2	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	8.8	GO:0005694	chromosome(GO:0005694)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.5	49.7	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
2.8	11.4	GO:0097001	ceramide binding(GO:0097001)
2.4	9.5	GO:0042030	ATPase inhibitor activity(GO:0042030)
2.2	6.7	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
1.0	4.0	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.9	7.5	GO:0050816	phosphothreonine binding(GO:0050816)
0.8	13.4	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.7	9.8	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.6	1.9	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6	15.1	GO:0048156	tau protein binding(GO:0048156)
0.5	16.1	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.5	5.7	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5	32.3	GO:0070888	E-box binding(GO:0070888)
0.4	4.0	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.4	13.4	GO:0005521	lamin binding(GO:0005521)
0.4	5.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.4	8.0	GO:0030957	Tat protein binding(GO:0030957)
0.4	6.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.4	8.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.4	19.3	GO:0030552	cAMP binding(GO:0030552)
0.3	1.7	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3	2.0	GO:0043237	laminin-1 binding(GO:0043237)
0.3	1.0	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.3	5.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.3	2.6	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3	0.8	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.2	2.7	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	5.9	GO:0051010	microtubule plus-end binding(GO:0051010)
0.2	7.8	GO:0042056	chemoattractant activity(GO:0042056)
0.2	4.9	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.2	1.1	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	2.0	GO:0039706	co-receptor binding(GO:0039706)
0.2	1.4	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2	3.1	GO:0002162	dystroglycan binding(GO:0002162)
0.2	47.2	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1	1.9	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	1.5	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.4	GO:0031862	prostanoid receptor binding(GO:0031862)
0.1	1.0	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1	22.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	1.4	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	0.8	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.1	3.6	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	0.7	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.3	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	1.6	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	23.1	GO:0005057	receptor signaling protein activity(GO:0005057)
0.1	4.4	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	4.9	GO:0015485	cholesterol binding(GO:0015485)
0.1	3.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	1.6	GO:0070300	phosphatidic acid binding(GO:0070300)
0.1	1.2	GO:0008432	JUN kinase binding(GO:0008432)
0.1	6.9	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.1	1.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	2.3	GO:0050699	WW domain binding(GO:0050699)
0.1	0.8	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.4	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.1	1.2	GO:0019208	phosphatase regulator activity(GO:0019208)
0.1	1.9	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	2.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.4	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0005124	N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.0	4.6	GO:0001618	virus receptor activity(GO:0001618)
0.0	4.1	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	0.7	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.7	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.3	GO:0032052	bile acid binding(GO:0032052)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	49.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.2	10.9	PID MYC PATHWAY	C-MYC pathway
0.2	5.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	15.1	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	4.5	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	1.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	3.4	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	16.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	5.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	4.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	6.4	PID FGF PATHWAY	FGF signaling pathway
0.1	3.1	PID LKB1 PATHWAY	LKB1 signaling events
0.1	6.8	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	1.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	2.3	PID ATR PATHWAY	ATR signaling pathway
0.0	4.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.8	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	3.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	5.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.7	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	1.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.8	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.3	PID IL23 PATHWAY	IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	49.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.7	19.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.4	16.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.4	13.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.3	6.7	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	11.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.2	2.6	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	5.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.2	3.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	8.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	4.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	7.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	4.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	9.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	4.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	5.2	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	5.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	1.9	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.1	2.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	4.4	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	1.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	4.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	1.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.0	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	1.5	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	1.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	2.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.6	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type