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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOXD3_FOXI1_FOXF1

Z-value: 1.01

Motif logo

Transcription factors associated with FOXD3_FOXI1_FOXF1

Gene Symbol Gene ID Gene Info
ENSG00000187140.6 FOXD3
ENSG00000168269.10 FOXI1
ENSG00000103241.7 FOXF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXI1hg38_v1_chr5_+_170105892_1701059130.212.0e-03Click!
FOXF1hg38_v1_chr16_+_86510507_865105390.186.8e-03Click!
FOXD3hg38_v1_chr1_+_63322558_633225830.063.6e-01Click!

Activity profile of FOXD3_FOXI1_FOXF1 motif

Sorted Z-values of FOXD3_FOXI1_FOXF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD3_FOXI1_FOXF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_111910888 24.69 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr11_-_111910790 23.57 ENST00000533280.6
crystallin alpha B
chr2_+_172860038 19.41 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr11_-_111910830 19.26 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr3_-_195583931 17.70 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr1_+_50105666 16.66 ENST00000651347.1
ELAV like RNA binding protein 4
chr5_+_174045673 15.98 ENST00000303177.8
ENST00000519867.5
neuronal vesicle trafficking associated 2
chr4_-_152382522 15.79 ENST00000296555.11
F-box and WD repeat domain containing 7
chr5_-_88883701 14.31 ENST00000636998.1
myocyte enhancer factor 2C
chr4_+_70721953 14.20 ENST00000381006.8
ENST00000226328.8
RUN and FYVE domain containing 3
chr1_-_56579555 13.77 ENST00000371250.4
phospholipid phosphatase 3
chr16_+_7303245 13.50 ENST00000674626.1
RNA binding fox-1 homolog 1
chr5_-_146922515 12.73 ENST00000508545.6
protein phosphatase 2 regulatory subunit Bbeta
chr12_+_10212867 12.64 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr11_+_114059755 12.40 ENST00000684295.1
zinc finger and BTB domain containing 16
chr7_+_86643902 12.29 ENST00000361669.7
glutamate metabotropic receptor 3
chr4_-_87529359 12.03 ENST00000458304.2
ENST00000282470.11
SPARC like 1
chr16_+_6019585 11.97 ENST00000547372.5
RNA binding fox-1 homolog 1
chr4_-_87529092 11.78 ENST00000503414.5
SPARC like 1
chr16_+_56191476 11.49 ENST00000262493.12
G protein subunit alpha o1
chr3_-_58587033 11.37 ENST00000447756.2
family with sequence similarity 107 member A
chr13_+_32031706 10.42 ENST00000542859.6
FRY microtubule binding protein
chr10_+_10798570 10.31 ENST00000638035.1
ENST00000636488.1
CUGBP Elav-like family member 2
chr5_-_176630364 10.21 ENST00000310112.7
synuclein beta
chr5_-_176629943 10.06 ENST00000510387.5
ENST00000506696.1
synuclein beta
chr12_+_79045625 9.77 ENST00000552744.5
synaptotagmin 1
chr5_-_88883420 9.25 ENST00000437473.6
myocyte enhancer factor 2C
chr3_+_35679614 9.24 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
cAMP regulated phosphoprotein 21
chr2_-_174846405 8.75 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr10_+_93758063 8.68 ENST00000627699.1
ENST00000371413.4
leucine rich glioma inactivated 1
chr8_-_119638780 8.32 ENST00000522826.5
ENST00000520066.5
ENST00000259486.10
ENST00000075322.11
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr17_-_39607876 8.32 ENST00000302584.5
neuronal differentiation 2
chr18_-_55403682 7.90 ENST00000564228.5
ENST00000630828.2
transcription factor 4
chr1_+_204870831 7.83 ENST00000404076.5
ENST00000539706.6
neurofascin
chr5_-_24644968 7.80 ENST00000264463.8
cadherin 10
chr2_-_144516154 7.70 ENST00000637304.1
zinc finger E-box binding homeobox 2
chr2_+_165239432 7.64 ENST00000636071.2
ENST00000636985.2
sodium voltage-gated channel alpha subunit 2
chr14_+_22829879 7.62 ENST00000355151.9
ENST00000397496.7
ENST00000555345.5
ENST00000432849.7
ENST00000553711.5
ENST00000556465.5
ENST00000397505.2
ENST00000557221.1
ENST00000556840.5
ENST00000555536.1
mitochondrial ribosomal protein L52
chr16_+_6019016 7.48 ENST00000550418.6
RNA binding fox-1 homolog 1
chr10_+_93757831 7.35 ENST00000629035.2
leucine rich glioma inactivated 1
chr2_-_144516397 7.32 ENST00000638128.1
zinc finger E-box binding homeobox 2
chr11_+_114060204 7.13 ENST00000683318.1
zinc finger and BTB domain containing 16
chr3_-_127736329 6.90 ENST00000398101.7
monoglyceride lipase
chrX_-_13817346 6.90 ENST00000356942.9
glycoprotein M6B
chr2_+_165294031 6.87 ENST00000283256.10
sodium voltage-gated channel alpha subunit 2
chr2_+_172928165 6.84 ENST00000535187.5
Rap guanine nucleotide exchange factor 4
chr16_+_6019071 6.78 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr3_+_159273235 6.59 ENST00000638749.1
IQCJ-SCHIP1 readthrough
chr3_+_39467672 6.56 ENST00000436143.6
ENST00000441980.6
ENST00000682069.1
ENST00000311042.10
myelin associated oligodendrocyte basic protein
chr2_+_165239388 6.40 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
sodium voltage-gated channel alpha subunit 2
chr3_+_39467598 6.28 ENST00000428261.5
ENST00000420739.5
ENST00000415443.5
ENST00000447324.5
ENST00000383754.7
myelin associated oligodendrocyte basic protein
chr7_-_37448845 6.18 ENST00000310758.9
engulfment and cell motility 1
chr5_-_142686079 6.17 ENST00000337706.7
fibroblast growth factor 1
chr10_+_93757857 6.14 ENST00000478763.2
ENST00000371418.9
ENST00000630184.2
ENST00000630047.2
ENST00000637689.1
leucine rich glioma inactivated 1
chr12_+_101594849 6.08 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr10_-_121596117 6.03 ENST00000351936.11
fibroblast growth factor receptor 2
chr2_-_144517663 5.76 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr17_-_31314066 5.66 ENST00000577894.1
ecotropic viral integration site 2B
chr7_+_121873152 5.62 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
protein tyrosine phosphatase receptor type Z1
chr6_-_152168291 5.60 ENST00000354674.5
spectrin repeat containing nuclear envelope protein 1
chr11_+_13962676 5.56 ENST00000576479.4
spondin 1
chr6_-_152168349 5.55 ENST00000539504.5
spectrin repeat containing nuclear envelope protein 1
chr4_-_98657635 5.51 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
tetraspanin 5
chr8_+_78516329 5.40 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr19_-_40413364 5.32 ENST00000291825.11
ENST00000324001.8
periaxin
chr8_+_24914942 5.31 ENST00000433454.3
neurofilament medium
chr12_+_50925007 5.28 ENST00000332160.5
methyltransferase like 7A
chr4_-_101347492 5.25 ENST00000394854.8
protein phosphatase 3 catalytic subunit alpha
chr11_+_93746433 5.20 ENST00000526335.1
chromosome 11 open reading frame 54
chr4_-_101347327 5.18 ENST00000394853.8
protein phosphatase 3 catalytic subunit alpha
chr2_-_174847015 5.14 ENST00000650938.1
chimerin 1
chr12_-_21334858 4.97 ENST00000445053.1
ENST00000458504.5
ENST00000422327.5
ENST00000683939.1
solute carrier organic anion transporter family member 1A2
chr1_-_9751540 4.95 ENST00000435891.5
calsyntenin 1
chrX_-_13817027 4.89 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr13_+_31945826 4.88 ENST00000647500.1
FRY microtubule binding protein
chr13_-_35855758 4.88 ENST00000615680.4
doublecortin like kinase 1
chr4_-_175812746 4.82 ENST00000393658.6
glycoprotein M6A
chr3_+_159069252 4.71 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr12_-_98644733 4.71 ENST00000299157.5
ENST00000393042.3
IKBKB interacting protein
chr7_+_121873317 4.68 ENST00000651863.1
ENST00000652298.1
ENST00000449182.1
protein tyrosine phosphatase receptor type Z1
chr14_-_21023954 4.68 ENST00000554094.5
NDRG family member 2
chr8_+_84183262 4.68 ENST00000522455.5
ENST00000521695.5
ENST00000521268.6
RALY RNA binding protein like
chr2_+_172821575 4.67 ENST00000397087.7
Rap guanine nucleotide exchange factor 4
chr19_+_3880647 4.67 ENST00000450849.7
ATCAY kinesin light chain interacting caytaxin
chr8_-_19013649 4.58 ENST00000440756.4
pleckstrin and Sec7 domain containing 3
chr3_-_16482850 4.58 ENST00000432519.5
raftlin, lipid raft linker 1
chr4_-_101347471 4.56 ENST00000323055.10
ENST00000512215.5
protein phosphatase 3 catalytic subunit alpha
chr11_+_108665122 4.52 ENST00000526794.1
DEAD-box helicase 10
chr4_+_153257339 4.50 ENST00000676374.1
ENST00000676196.1
ENST00000674935.1
ENST00000674769.1
ENST00000674896.1
ENST00000676191.1
ENST00000675312.1
ENST00000675456.1
ENST00000674847.1
ENST00000675977.1
ENST00000676264.1
ENST00000674726.1
ENST00000676252.1
ENST00000674730.1
ENST00000675738.1
ENST00000482578.3
tripartite motif containing 2
chr3_-_114624193 4.47 ENST00000481632.5
zinc finger and BTB domain containing 20
chr9_-_119369416 4.45 ENST00000373964.2
ENST00000265922.8
BMP/retinoic acid inducible neural specific 1
chr4_+_74308463 4.38 ENST00000413830.6
epithelial mitogen
chr11_+_65890627 4.33 ENST00000312579.4
coiled-coil domain containing 85B
chr14_-_21024092 4.24 ENST00000554398.5
NDRG family member 2
chr5_-_172771187 4.23 ENST00000239223.4
dual specificity phosphatase 1
chr2_-_112255015 4.15 ENST00000615791.1
ENST00000409573.7
ENST00000272570.9
zinc finger CCCH-type containing 8
chrM_+_4467 4.15 ENST00000361453.3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr14_-_21025000 4.12 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr11_-_78341876 4.09 ENST00000340149.6
GRB2 associated binding protein 2
chr19_+_57240610 3.97 ENST00000414468.3
zinc finger protein 805
chr6_+_101398788 3.96 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
glutamate ionotropic receptor kainate type subunit 2
chr7_+_121873478 3.84 ENST00000651320.1
protein tyrosine phosphatase receptor type Z1
chr7_+_121873089 3.79 ENST00000651065.1
protein tyrosine phosphatase receptor type Z1
chr1_-_152360004 3.78 ENST00000388718.5
filaggrin family member 2
chr1_-_167553799 3.74 ENST00000466652.2
cellular repressor of E1A stimulated genes 1
chr12_-_26125023 3.74 ENST00000242728.5
basic helix-loop-helix family member e41
chr1_+_50106265 3.71 ENST00000357083.8
ELAV like RNA binding protein 4
chr17_-_31314040 3.71 ENST00000330927.5
ecotropic viral integration site 2B
chr2_-_2324323 3.71 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr2_+_80305105 3.71 ENST00000541047.5
catenin alpha 2
chr4_+_164754116 3.66 ENST00000507311.1
small integral membrane protein 31
chr1_-_23913353 3.60 ENST00000374472.5
cannabinoid receptor 2
chr1_-_226739271 3.58 ENST00000429204.6
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr11_-_107712049 3.57 ENST00000305991.3
sarcolipin
chr1_-_27626229 3.56 ENST00000399173.5
FGR proto-oncogene, Src family tyrosine kinase
chr21_-_32612806 3.52 ENST00000673807.1
CFAP298-TCP10L readthrough
chr18_-_5540515 3.51 ENST00000544123.5
ENST00000585142.5
erythrocyte membrane protein band 4.1 like 3
chr2_-_2324642 3.49 ENST00000650485.1
ENST00000649207.1
myelin transcription factor 1 like
chr11_-_5234475 3.40 ENST00000292901.7
ENST00000650601.1
ENST00000417377.1
hemoglobin subunit delta
chr4_+_20251896 3.39 ENST00000504154.6
slit guidance ligand 2
chr18_-_55585773 3.34 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr14_+_90397019 3.32 ENST00000447653.8
ENST00000356978.9
ENST00000626705.2
calmodulin 1
chr12_+_12725897 3.32 ENST00000326765.10
apolipoprotein L domain containing 1
chr7_-_88220025 3.32 ENST00000419179.5
ENST00000265729.7
sorcin
chr17_-_75855204 3.32 ENST00000589642.5
ENST00000593002.1
ENST00000590221.5
ENST00000587374.5
ENST00000585462.5
ENST00000254806.8
ENST00000433525.6
ENST00000626827.2
WW domain binding protein 2
chr14_-_21025490 3.32 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr1_+_226223618 3.30 ENST00000542034.5
ENST00000366810.6
Mix paired-like homeobox
chr12_+_77830886 3.28 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr4_+_153204410 3.24 ENST00000675838.1
ENST00000674967.1
ENST00000632856.2
ENST00000441616.6
ENST00000433687.2
ENST00000494872.6
ENST00000460908.2
ENST00000675780.1
ENST00000674976.1
ENST00000338700.10
ENST00000675293.1
ENST00000676172.1
ENST00000675673.1
ENST00000675492.1
ENST00000675425.1
ENST00000675384.1
ENST00000675063.1
ENST00000675340.1
ENST00000675835.1
ENST00000675054.1
ENST00000675710.1
ENST00000502281.3
novel protein
tripartite motif containing 2
chr5_-_42811884 3.23 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr15_+_78438279 3.23 ENST00000560440.5
iron responsive element binding protein 2
chr3_+_119597874 3.20 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
phospholipase A1 member A
chr3_-_187745460 3.19 ENST00000406870.7
BCL6 transcription repressor
chr7_+_152074292 3.16 ENST00000434507.5
polypeptide N-acetylgalactosaminyltransferase 11
chr18_-_55510753 3.12 ENST00000543082.5
transcription factor 4
chr1_-_170074568 3.12 ENST00000367767.5
ENST00000361580.7
ENST00000538366.5
kinesin associated protein 3
chr12_-_91182784 3.06 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chrX_+_108045050 3.04 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr17_-_68955332 3.03 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr11_+_27055215 3.01 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr11_+_63536801 3.00 ENST00000255688.8
ENST00000439013.6
phospholipase A and acyltransferase 4
chr5_+_162068031 3.00 ENST00000356592.8
gamma-aminobutyric acid type A receptor subunit gamma2
chr3_+_124384513 2.97 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
kalirin RhoGEF kinase
chr4_-_89838289 2.96 ENST00000336904.7
synuclein alpha
chr14_+_91114026 2.96 ENST00000521081.5
ENST00000520328.5
ENST00000524232.5
ENST00000522170.5
ENST00000256324.15
ENST00000519950.5
ENST00000523879.5
ENST00000521077.6
ENST00000518665.6
D-glutamate cyclase
chr5_+_131170936 2.96 ENST00000510516.5
ENST00000379380.9
ENST00000507584.1
LYR motif containing 7
chr18_+_34976928 2.94 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr19_+_45467988 2.92 ENST00000615753.4
ENST00000585836.5
ENST00000417353.6
ENST00000591858.5
ENST00000443841.6
ENST00000590335.1
ENST00000353609.8
FosB proto-oncogene, AP-1 transcription factor subunit
chr11_-_790062 2.89 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr3_-_138174879 2.87 ENST00000260803.9
debranching RNA lariats 1
chr5_+_93583212 2.86 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr1_-_177164673 2.85 ENST00000424564.2
ENST00000361833.7
astrotactin 1
chr1_-_173669835 2.83 ENST00000333279.3
ankyrin repeat domain 45
chr3_+_45026296 2.82 ENST00000296130.5
C-type lectin domain family 3 member B
chrX_+_108044967 2.81 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr2_-_71227055 2.77 ENST00000244221.9
poly(A) binding protein interacting protein 2B
chr4_-_86360071 2.73 ENST00000641677.1
ENST00000639234.1
ENST00000641553.1
ENST00000641826.1
ENST00000641537.1
ENST00000395169.9
ENST00000641408.1
ENST00000638225.1
ENST00000641052.1
mitogen-activated protein kinase 10
chr5_-_128339191 2.72 ENST00000507835.5
fibrillin 2
chr4_-_89835617 2.72 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr14_+_91114431 2.70 ENST00000428926.6
ENST00000517362.5
D-glutamate cyclase
chr19_-_54115626 2.66 ENST00000391759.6
TCF3 fusion partner
chr1_+_207104226 2.66 ENST00000367070.8
complement component 4 binding protein alpha
chr1_+_2073986 2.65 ENST00000461106.6
protein kinase C zeta
chr18_-_55586092 2.65 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chrX_-_108736556 2.64 ENST00000372129.4
insulin receptor substrate 4
chr15_-_55365231 2.62 ENST00000568543.1
cell cycle progression 1
chr8_+_27774530 2.57 ENST00000305188.13
establishment of sister chromatid cohesion N-acetyltransferase 2
chr14_-_44961889 2.57 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
kelch like family member 28
chr2_-_2331225 2.55 ENST00000648627.1
ENST00000649663.1
ENST00000650560.1
ENST00000428368.7
ENST00000648316.1
ENST00000648665.1
ENST00000649313.1
ENST00000399161.7
ENST00000647738.2
myelin transcription factor 1 like
chr11_-_62832033 2.54 ENST00000377897.8
ENST00000394690.5
ENST00000294179.8
syntaxin 5
chr3_+_171843337 2.53 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr14_+_91114364 2.52 ENST00000518868.5
D-glutamate cyclase
chr5_-_131796921 2.50 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr14_+_91114388 2.50 ENST00000519019.5
ENST00000523816.5
ENST00000517518.5
D-glutamate cyclase
chr10_-_60389833 2.50 ENST00000280772.7
ankyrin 3
chr8_+_84183534 2.49 ENST00000518566.5
RALY RNA binding protein like
chr4_+_85475131 2.49 ENST00000395184.6
Rho GTPase activating protein 24
chr10_+_117543567 2.47 ENST00000616794.1
empty spiracles homeobox 2
chr11_-_49208372 2.47 ENST00000533034.1
folate hydrolase 1
chr2_+_235494024 2.47 ENST00000304032.13
ENST00000409457.5
ENST00000336665.9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr11_+_112961247 2.46 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
neural cell adhesion molecule 1
chr7_+_139829242 2.45 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
thromboxane A synthase 1
chrX_-_9034127 2.45 ENST00000327220.10
family with sequence similarity 9 member B
chr10_+_110207587 2.43 ENST00000332674.9
ENST00000453116.5
MAX interactor 1, dimerization protein
chr11_-_46617170 2.41 ENST00000326737.3
harbinger transposase derived 1
chr9_+_75890664 2.41 ENST00000376767.7
ENST00000674117.1
ENST00000376752.8
proprotein convertase subtilisin/kexin type 5
chr1_+_220528333 2.39 ENST00000677505.1
microtubule affinity regulating kinase 1
chr18_-_55422492 2.39 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr14_+_91114667 2.38 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
D-glutamate cyclase
chr6_-_46954922 2.36 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr6_-_13487593 2.36 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr5_+_162067858 2.34 ENST00000361925.9
gamma-aminobutyric acid type A receptor subunit gamma2
chr5_-_138875290 2.32 ENST00000521094.2
ENST00000274711.7
leucine rich repeat transmembrane neuronal 2
chr12_+_55019967 2.31 ENST00000242994.4
neuronal differentiation 4
chr5_-_142698004 2.30 ENST00000407758.5
ENST00000441680.6
ENST00000419524.6
ENST00000621536.4
fibroblast growth factor 1
chr4_+_153222402 2.30 ENST00000676335.1
ENST00000675146.1
tripartite motif containing 2
chr19_+_8418386 2.29 ENST00000602117.1
membrane associated ring-CH-type finger 2
chr12_-_55712402 2.28 ENST00000452168.6
integrin subunit alpha 7
chr18_-_63158208 2.27 ENST00000678301.1
BCL2 apoptosis regulator
chr4_-_86453075 2.25 ENST00000641384.1
ENST00000642009.1
ENST00000641274.1
ENST00000641629.1
ENST00000641718.1
ENST00000641782.1
ENST00000511328.5
ENST00000503911.5
ENST00000641862.1
ENST00000640445.1
ENST00000641675.1
ENST00000361569.8
ENST00000639989.2
ENST00000641120.1
ENST00000642023.1
ENST00000641902.1
ENST00000641016.1
ENST00000509464.7
ENST00000638946.2
ENST00000395160.9
ENST00000512017.7
ENST00000639972.2
mitogen-activated protein kinase 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 17.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
4.4 17.6 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
4.3 17.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
3.9 66.7 GO:0007021 tubulin complex assembly(GO:0007021)
3.8 15.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
3.3 9.8 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
3.3 19.5 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
3.1 24.8 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
3.0 24.0 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
2.1 8.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.6 19.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.6 20.9 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
1.3 5.3 GO:0033693 neurofilament bundle assembly(GO:0033693)
1.3 11.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.2 8.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
1.2 3.6 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
1.2 4.7 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
1.2 5.8 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
1.1 13.8 GO:0008354 germ cell migration(GO:0008354)
1.1 3.4 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
1.1 11.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.1 12.7 GO:0038171 cannabinoid signaling pathway(GO:0038171)
1.0 3.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.0 16.5 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
1.0 16.4 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.0 6.0 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
1.0 3.8 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.9 12.8 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.8 12.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.8 4.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.8 4.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.8 12.8 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.7 2.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.7 2.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.7 2.8 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.7 2.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.7 1.3 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.7 2.0 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.7 3.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.6 3.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.6 0.6 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.6 2.5 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.6 3.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.6 1.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.6 1.8 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.6 1.8 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.6 2.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.6 4.6 GO:0061709 reticulophagy(GO:0061709)
0.6 2.9 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.6 4.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 7.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.6 8.3 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.6 5.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.6 3.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.5 1.6 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.5 3.8 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.5 4.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.5 1.6 GO:0072425 cellular response to nitrosative stress(GO:0071500) signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.5 2.7 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
0.5 2.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.5 2.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5 1.0 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.5 3.6 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.5 2.5 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.5 38.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.5 4.4 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5 3.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 1.4 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.5 12.5 GO:0071420 cellular response to histamine(GO:0071420)
0.5 1.4 GO:0045425 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.4 1.3 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.4 6.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.4 1.7 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.4 1.7 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.4 1.2 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.4 3.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.4 3.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 3.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.4 5.2 GO:1902548 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.4 1.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.4 0.8 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.4 1.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4 2.6 GO:0042118 endothelial cell activation(GO:0042118)
0.4 7.6 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.4 1.4 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.4 1.1 GO:1903487 regulation of lactation(GO:1903487)
0.4 1.1 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.4 2.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 10.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 3.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 1.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.3 3.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.3 7.4 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.3 4.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 1.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 5.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 5.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 3.6 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.3 3.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.3 15.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.3 1.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 3.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 1.3 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 2.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280) Golgi disassembly(GO:0090166)
0.3 29.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.3 0.9 GO:0090135 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) actin filament branching(GO:0090135)
0.3 5.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 11.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.3 0.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.3 0.6 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.3 3.3 GO:0042908 xenobiotic transport(GO:0042908)
0.3 1.2 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 12.2 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.3 2.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 2.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.3 10.2 GO:0048665 neuron fate specification(GO:0048665)
0.3 14.6 GO:0042417 dopamine metabolic process(GO:0042417)
0.3 7.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 1.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.3 1.1 GO:0072007 mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.3 0.8 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 1.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.3 2.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 0.8 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 1.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 1.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 1.9 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.2 0.9 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.2 1.4 GO:0038016 insulin receptor internalization(GO:0038016)
0.2 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 1.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 2.4 GO:0043129 surfactant homeostasis(GO:0043129)
0.2 1.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.2 4.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.8 GO:0034627 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.2 1.9 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.2 0.6 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 0.6 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2 1.5 GO:0003096 renal sodium ion transport(GO:0003096)
0.2 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 1.2 GO:0044211 CTP salvage(GO:0044211)
0.2 0.8 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.2 0.6 GO:1990637 response to prolactin(GO:1990637)
0.2 0.8 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 0.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 0.8 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.2 0.8 GO:0042713 sperm ejaculation(GO:0042713)
0.2 8.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 3.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 0.4 GO:2000722 regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722)
0.2 3.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 0.6 GO:0033168 regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040) conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404)
0.2 2.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.2 1.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 1.8 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.2 0.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.2 0.5 GO:1990910 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.2 2.7 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.2 3.4 GO:0015671 oxygen transport(GO:0015671)
0.2 2.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 1.4 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.2 3.7 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2 1.2 GO:0048241 epinephrine transport(GO:0048241)
0.2 0.5 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.2 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.5 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.2 0.8 GO:1901374 acetate ester transport(GO:1901374)
0.2 0.5 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.2 3.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 0.7 GO:0010193 response to ozone(GO:0010193)
0.2 2.8 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.2 1.8 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.8 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.2 1.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.2 1.8 GO:0007379 segment specification(GO:0007379)
0.2 0.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 6.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.2 4.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 1.4 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.2 4.7 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.2 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 1.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 4.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 2.0 GO:1990440 ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 1.8 GO:0060346 bone trabecula formation(GO:0060346)
0.1 1.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 1.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.6 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.7 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 1.6 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 23.8 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.1 0.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 1.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.1 GO:2000143 negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1 2.1 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.1 1.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.3 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.8 GO:0048820 hair follicle maturation(GO:0048820)
0.1 1.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 3.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 1.6 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 1.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.4 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 4.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 2.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.7 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.9 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 1.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.3 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.8 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.9 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 1.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 2.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.1 0.3 GO:0009597 detection of virus(GO:0009597)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 1.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.7 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.8 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.7 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.1 0.5 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.5 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 1.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 3.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.1 GO:0038001 paracrine signaling(GO:0038001)
0.1 0.9 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.4 GO:0060290 transdifferentiation(GO:0060290)
0.1 1.9 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.1 0.6 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.1 0.3 GO:0001554 luteolysis(GO:0001554)
0.1 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 1.5 GO:0035855 megakaryocyte development(GO:0035855)
0.1 7.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.3 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 1.1 GO:0014029 neural crest formation(GO:0014029)
0.1 0.3 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 1.4 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.6 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.1 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.6 GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078)
0.1 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.1 1.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 2.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 1.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 1.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.2 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 2.2 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.6 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.7 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1 0.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 2.4 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.7 GO:1901740 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) positive regulation of hepatocyte proliferation(GO:2000347)
0.1 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.4 GO:0071625 vocalization behavior(GO:0071625)
0.1 1.4 GO:0030325 adrenal gland development(GO:0030325)
0.1 0.3 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.3 GO:0030903 notochord development(GO:0030903)
0.1 2.2 GO:1901998 toxin transport(GO:1901998)
0.1 0.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.8 GO:0008038 neuron recognition(GO:0008038)
0.1 1.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.0 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.4 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.3 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 3.2 GO:0006826 iron ion transport(GO:0006826)
0.1 14.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.6 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 3.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.4 GO:0007635 chemosensory behavior(GO:0007635)
0.1 2.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 1.4 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.1 7.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.3 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.1 0.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 1.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.3 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.3 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 1.1 GO:0090314 positive regulation of protein targeting to membrane(GO:0090314)
0.0 0.1 GO:0051036 regulation of endosome size(GO:0051036)
0.0 0.3 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0060872 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.2 GO:1900229 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 1.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 1.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 2.2 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 2.2 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.5 GO:0032570 response to progesterone(GO:0032570)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 2.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.4 GO:0072540 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 cell lineage commitment(GO:0072540)
0.0 1.2 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:1901748 glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.8 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.4 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.2 GO:1901538 DNA methylation involved in embryo development(GO:0043045) C-5 methylation of cytosine(GO:0090116) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 1.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0072248 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.8 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.0 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0032747 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.9 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.7 GO:0042026 protein refolding(GO:0042026)
0.0 1.8 GO:0051899 membrane depolarization(GO:0051899)
0.0 0.4 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0048535 lymph node development(GO:0048535)
0.0 0.5 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.3 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.0 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 67.5 GO:0097512 cardiac myofibril(GO:0097512)
3.6 17.9 GO:0072534 perineuronal net(GO:0072534)
2.5 17.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.0 9.8 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.7 19.0 GO:0005955 calcineurin complex(GO:0005955)
1.6 32.3 GO:0033270 paranode region of axon(GO:0033270)
1.0 3.1 GO:0016939 kinesin II complex(GO:0016939)
1.0 4.2 GO:0035363 histone locus body(GO:0035363)
0.9 11.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6 25.9 GO:0032590 dendrite membrane(GO:0032590)
0.5 2.7 GO:0001652 granular component(GO:0001652)
0.5 6.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 3.3 GO:0042584 chromaffin granule membrane(GO:0042584) dendritic spine neck(GO:0044326)
0.5 3.3 GO:0019867 outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.4 1.7 GO:0070695 FHF complex(GO:0070695)
0.4 1.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.4 5.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.4 13.2 GO:0071437 invadopodium(GO:0071437)
0.4 4.4 GO:0016013 syntrophin complex(GO:0016013)
0.4 1.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.0 GO:0031251 PAN complex(GO:0031251)
0.3 1.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 5.3 GO:0005883 neurofilament(GO:0005883)
0.3 2.7 GO:0045179 apical cortex(GO:0045179)
0.3 1.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 11.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 1.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.3 3.3 GO:0097486 multivesicular body lumen(GO:0097486)
0.3 0.8 GO:1990075 periciliary membrane compartment(GO:1990075)
0.3 1.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.3 6.9 GO:0032982 myosin filament(GO:0032982)
0.2 2.0 GO:0070852 cell body fiber(GO:0070852)
0.2 3.4 GO:0005833 hemoglobin complex(GO:0005833)
0.2 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.7 GO:0036398 TCR signalosome(GO:0036398)
0.2 1.5 GO:0036157 outer dynein arm(GO:0036157)
0.2 1.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 4.3 GO:0043194 axon initial segment(GO:0043194)
0.2 3.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 7.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 4.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 0.6 GO:0033167 ARC complex(GO:0033167)
0.2 1.6 GO:0031209 SCAR complex(GO:0031209)
0.2 2.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 4.5 GO:0044295 axonal growth cone(GO:0044295)
0.2 2.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 5.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 31.2 GO:0030427 site of polarized growth(GO:0030427)
0.2 1.3 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 1.3 GO:0034464 BBSome(GO:0034464)
0.2 11.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 0.5 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 0.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 6.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 0.9 GO:0000322 storage vacuole(GO:0000322)
0.2 2.4 GO:0000800 lateral element(GO:0000800)
0.2 2.6 GO:0010369 chromocenter(GO:0010369)
0.1 2.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.4 GO:0071439 clathrin complex(GO:0071439)
0.1 0.6 GO:0097165 nuclear stress granule(GO:0097165)
0.1 2.7 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 0.8 GO:0030897 HOPS complex(GO:0030897)
0.1 1.8 GO:0030673 axolemma(GO:0030673)
0.1 2.8 GO:0002080 acrosomal membrane(GO:0002080)
0.1 32.6 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.7 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.1 13.2 GO:0016605 PML body(GO:0016605)
0.1 11.7 GO:0016234 inclusion body(GO:0016234)
0.1 0.5 GO:0036128 CatSper complex(GO:0036128)
0.1 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.4 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 0.6 GO:0032437 cuticular plate(GO:0032437)
0.1 29.0 GO:0060076 excitatory synapse(GO:0060076)
0.1 4.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 4.3 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.1 GO:0005771 multivesicular body(GO:0005771)
0.1 1.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.8 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 15.7 GO:0030425 dendrite(GO:0030425)
0.1 1.6 GO:0032300 mismatch repair complex(GO:0032300)
0.1 15.4 GO:0032993 protein-DNA complex(GO:0032993)
0.1 3.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.2 GO:0030315 T-tubule(GO:0030315)
0.1 2.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 25.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 2.5 GO:0031201 SNARE complex(GO:0031201)
0.1 5.7 GO:0005811 lipid particle(GO:0005811)
0.1 0.2 GO:0001940 male pronucleus(GO:0001940)
0.1 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 5.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 35.7 GO:0045202 synapse(GO:0045202)
0.0 0.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 2.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 2.8 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.6 GO:0001772 immunological synapse(GO:0001772)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 2.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 2.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 5.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.0 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227) intrinsic component of organelle membrane(GO:0031300)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 69.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.7 GO:0016324 apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
2.3 13.8 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
2.3 67.7 GO:0005212 structural constituent of eye lens(GO:0005212)
2.2 17.6 GO:0050816 phosphothreonine binding(GO:0050816)
2.1 8.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
2.0 17.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
2.0 9.8 GO:0030348 syntaxin-3 binding(GO:0030348)
1.8 27.7 GO:1903136 cuprous ion binding(GO:1903136)
1.5 4.6 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.5 25.8 GO:0003680 AT DNA binding(GO:0003680)
1.5 18.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.5 16.0 GO:0032051 clathrin light chain binding(GO:0032051)
1.4 4.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.4 5.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.3 3.8 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
1.2 25.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.2 3.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.1 3.2 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
1.1 3.2 GO:0030350 iron-responsive element binding(GO:0030350)
1.1 12.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.7 11.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.7 24.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.7 11.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.7 3.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.6 10.9 GO:0031432 titin binding(GO:0031432)
0.6 1.9 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.6 13.2 GO:0050811 GABA receptor binding(GO:0050811)
0.6 2.5 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.6 28.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.6 9.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.6 5.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.6 18.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.6 3.4 GO:0043237 laminin-1 binding(GO:0043237)
0.6 2.8 GO:0004447 iodide peroxidase activity(GO:0004447)
0.6 7.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.6 2.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.5 4.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 22.3 GO:0017091 AU-rich element binding(GO:0017091)
0.5 2.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.5 8.5 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.5 1.6 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.5 2.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.5 3.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.5 1.5 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.5 6.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.5 5.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.5 4.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.5 24.8 GO:0030552 cAMP binding(GO:0030552)
0.4 2.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.4 1.3 GO:0070052 collagen V binding(GO:0070052)
0.4 2.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 3.7 GO:0043426 MRF binding(GO:0043426)
0.4 1.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.4 2.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.4 2.0 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.4 11.2 GO:0005521 lamin binding(GO:0005521)
0.4 2.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.4 1.6 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 2.7 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.4 5.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.4 2.6 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.4 2.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 0.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.4 2.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 27.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 3.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.3 1.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.3 1.3 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 3.8 GO:0008430 selenium binding(GO:0008430)
0.3 0.9 GO:0032427 GBD domain binding(GO:0032427)
0.3 3.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 1.8 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.3 1.2 GO:0019770 IgG receptor activity(GO:0019770)
0.3 1.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.3 0.8 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.3 2.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.3 3.0 GO:0051434 BH3 domain binding(GO:0051434)
0.2 1.0 GO:0004771 sterol esterase activity(GO:0004771)
0.2 5.2 GO:0002162 dystroglycan binding(GO:0002162)
0.2 8.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 3.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 0.9 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 13.7 GO:0015485 cholesterol binding(GO:0015485)
0.2 1.4 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 3.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 0.8 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.2 2.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 1.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 6.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 2.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 2.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 2.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 1.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.8 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 1.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 1.8 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.2 0.9 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.2 2.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 1.2 GO:0004849 uridine kinase activity(GO:0004849)
0.2 3.7 GO:0043274 phospholipase binding(GO:0043274)
0.2 1.9 GO:0042577 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.2 2.0 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 8.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 0.6 GO:0050693 LBD domain binding(GO:0050693)
0.2 0.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 2.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 1.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.8 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.2 0.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 1.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.4 GO:0005549 odorant binding(GO:0005549)
0.1 8.2 GO:0019894 kinesin binding(GO:0019894)
0.1 2.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.8 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.1 1.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 4.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 2.0 GO:1900750 oligopeptide binding(GO:1900750)
0.1 0.8 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.0 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 2.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 4.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 2.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 3.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.6 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 1.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 3.4 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 8.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 37.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 3.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 4.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.1 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.6 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 0.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.1 GO:0019864 IgG binding(GO:0019864)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 2.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.6 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 9.7 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.4 GO:0005113 patched binding(GO:0005113)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 4.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.3 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 1.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 6.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.8 GO:0045159 myosin II binding(GO:0045159)
0.1 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 2.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.2 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 6.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 1.0 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 5.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.6 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.0 GO:0000146 microfilament motor activity(GO:0000146)
0.0 4.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.0 0.3 GO:1990239 steroid hormone binding(GO:1990239)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0032934 sterol binding(GO:0032934)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 12.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.4 26.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.3 25.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 19.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 3.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 15.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 12.9 PID MYC PATHWAY C-MYC pathway
0.2 1.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 45.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 9.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 13.8 PID FGF PATHWAY FGF signaling pathway
0.2 9.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 14.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 5.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 11.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 7.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.5 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 3.1 PID ATR PATHWAY ATR signaling pathway
0.1 3.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.0 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 31.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.7 1.5 REACTOME TRIF MEDIATED TLR3 SIGNALING Genes involved in TRIF mediated TLR3 signaling
0.7 49.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.7 13.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 14.5 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.6 24.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 10.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 9.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 16.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 9.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 12.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 12.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 3.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 10.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 5.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 6.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 5.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 3.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 10.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 3.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.9 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 6.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 0.7 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1 2.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 1.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 5.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 4.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 16.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.9 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.1 0.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 5.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 6.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 3.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 3.2 REACTOME SIGNALING BY FGFR MUTANTS Genes involved in Signaling by FGFR mutants
0.1 1.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 5.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME SHC MEDIATED CASCADE Genes involved in SHC-mediated cascade
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 3.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism