GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
FOXO4 Links Ensembl NCBI GeneCards UniProt	ENSG00000184481.17	FOXO4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXO4	hg38_v1_chrX_+_71095838_71095860	0.60	6.2e-23	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr9_+_127611760 Show fit	30.57	ENST00000625363.2 ENST00000626539.3	STXBP1 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 1
chr5_-_42811884 Show fit	30.21	ENST00000514985.6 ENST00000511224.5 ENST00000507920.5 ENST00000510965.1	SELENOP Links Ensembl NCBI GeneCards UniProt Show fit	selenoprotein P
chr5_-_131796921 Show fit	29.27	ENST00000307968.11 ENST00000307954.12	FNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	folliculin interacting protein 1
chr5_-_131797030 Show fit	26.52	ENST00000615660.4	FNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	folliculin interacting protein 1
chr14_-_59630582 Show fit	26.39	ENST00000395090.5	RTN1 Links Ensembl NCBI GeneCards UniProt Show fit	reticulon 1
chr16_+_6019585 Show fit	25.58	ENST00000547372.5	RBFOX1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr1_-_182391783 Show fit	25.25	ENST00000331872.11 ENST00000339526.8	GLUL Links Ensembl NCBI GeneCards UniProt Show fit	glutamate-ammonia ligase
chr1_-_182391323 Show fit	24.31	ENST00000642379.1	GLUL Links Ensembl NCBI GeneCards UniProt Show fit	glutamate-ammonia ligase
chr2_-_71227055 Show fit	23.65	ENST00000244221.9	PAIP2B Links Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein interacting protein 2B
chr1_+_92080305 Show fit	23.17	ENST00000342818.4 ENST00000636805.2	BTBD8 Links Ensembl NCBI GeneCards UniProt Show fit	BTB domain containing 8
chr11_-_62709493 Show fit	23.08	ENST00000405837.5 ENST00000531524.5 ENST00000524862.6 ENST00000679883.1	BSCL2 Links Ensembl NCBI GeneCards UniProt Show fit	BSCL2 lipid droplet biogenesis associated, seipin
chr1_-_182391363 Show fit	22.93	ENST00000417584.6	GLUL Links Ensembl NCBI GeneCards UniProt Show fit	glutamate-ammonia ligase
chr1_-_56579555 Show fit	22.61	ENST00000371250.4	PLPP3 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase 3
chr14_-_103521342 Show fit	21.79	ENST00000553610.5	CKB Links Ensembl NCBI GeneCards UniProt Show fit	creatine kinase B
chr20_+_45406560 Show fit	20.53	ENST00000372717.5 ENST00000360981.8	DBNDD2 Links Ensembl NCBI GeneCards UniProt Show fit	dysbindin domain containing 2
chr16_+_6019016 Show fit	20.41	ENST00000550418.6	RBFOX1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr19_-_36032799 Show fit	19.98	ENST00000592017.5 ENST00000360535.9	CLIP3 Links Ensembl NCBI GeneCards UniProt Show fit	CAP-Gly domain containing linker protein 3
chr16_+_6019071 Show fit	18.70	ENST00000547605.5 ENST00000553186.5	RBFOX1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr11_+_114060204 Show fit	18.68	ENST00000683318.1	ZBTB16 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 16
chr20_+_45407207 Show fit	18.12	ENST00000372712.6	DBNDD2 Links Ensembl NCBI GeneCards UniProt Show fit	dysbindin domain containing 2
chr2_-_2326210 Show fit	18.12	ENST00000647755.1	MYT1L Links Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr14_-_21025490 Show fit	18.09	ENST00000553442.5 ENST00000555869.5 ENST00000556457.5 ENST00000397844.6 ENST00000554415.5 ENST00000556974.5 ENST00000554419.5 ENST00000298687.9 ENST00000397858.5 ENST00000360463.7 ENST00000350792.7 ENST00000397847.6	NDRG2 Links Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 2
chr19_-_12610799 Show fit	17.93	ENST00000311437.11	ZNF490 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 490
chr17_-_17972374 Show fit	16.10	ENST00000318094.14 ENST00000540946.5 ENST00000379504.8 ENST00000542206.5 ENST00000395739.8 ENST00000581396.5 ENST00000535933.5 ENST00000579586.1	TOM1L2 Links Ensembl NCBI GeneCards UniProt Show fit	target of myb1 like 2 membrane trafficking protein
chr2_+_232662733 Show fit	15.99	ENST00000410095.5 ENST00000611312.1	EFHD1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain family member D1
chr16_+_56191476 Show fit	15.66	ENST00000262493.12	GNAO1 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha o1
chr17_-_44324770 Show fit	15.39	ENST00000592857.5 ENST00000586016.5 ENST00000590194.5 ENST00000588049.5 ENST00000586633.5 ENST00000377095.10 ENST00000537904.6 ENST00000585636.5 ENST00000585523.1 ENST00000225308.12	SLC25A39 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 39
chr17_+_17972813 Show fit	14.86	ENST00000582416.5 ENST00000313838.12 ENST00000399187.6 ENST00000581264.5 ENST00000479684.2 ENST00000584166.5 ENST00000585108.5 ENST00000399182.5 ENST00000579977.1	DRC3 Links Ensembl NCBI GeneCards UniProt Show fit	dynein regulatory complex subunit 3
chr8_-_133297092 Show fit	14.66	ENST00000522890.5 ENST00000675983.1 ENST00000518176.5 ENST00000323851.13 ENST00000522476.5 ENST00000518066.5 ENST00000521544.5 ENST00000674605.1 ENST00000518480.5 ENST00000523892.5	NDRG1 Links Ensembl NCBI GeneCards UniProt Show fit	N-myc downstream regulated 1
chr6_-_152168291 Show fit	14.19	ENST00000354674.5	SYNE1 Links Ensembl NCBI GeneCards UniProt Show fit	spectrin repeat containing nuclear envelope protein 1
chr19_-_36528232 Show fit	14.04	ENST00000592282.1 ENST00000523638.6	ZNF260 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 260
chr6_-_152168349 Show fit	14.01	ENST00000539504.5	SYNE1 Links Ensembl NCBI GeneCards UniProt Show fit	spectrin repeat containing nuclear envelope protein 1
chr19_+_12610912 Show fit	13.98	ENST00000446165.2 ENST00000343325.9	ZNF791 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 791
chr12_+_79045625 Show fit	13.37	ENST00000552744.5	SYT1 Links Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin 1
chr2_-_2326378 Show fit	13.16	ENST00000647618.1	MYT1L Links Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr19_+_49877425 Show fit	13.13	ENST00000622860.4	TBC1D17 Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 17
chr3_-_28348805 Show fit	12.64	ENST00000457172.5 ENST00000479665.6	AZI2 Links Ensembl NCBI GeneCards UniProt Show fit	5-azacytidine induced 2
chr1_+_162069768 Show fit	12.17	ENST00000530878.5	NOS1AP Links Ensembl NCBI GeneCards UniProt Show fit	nitric oxide synthase 1 adaptor protein
chr5_-_65624288 Show fit	11.93	ENST00000381018.7 ENST00000274327.11 ENST00000231524.14	TRIM23 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 23
chr6_+_101398788 Show fit	11.85	ENST00000369138.5 ENST00000413795.5 ENST00000358361.7	GRIK2 Links Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor kainate type subunit 2
chr19_+_49877660 Show fit	11.61	ENST00000535102.6	TBC1D17 Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 17
chr18_-_24272179 Show fit	11.42	ENST00000399443.7	OSBPL1A Links Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein like 1A
chr2_-_36966471 Show fit	11.41	ENST00000379213.3	STRN Links Ensembl NCBI GeneCards UniProt Show fit	striatin
chr3_+_124384513 Show fit	11.03	ENST00000682540.1 ENST00000522553.6 ENST00000682695.1 ENST00000682674.1 ENST00000684382.1	KALRN Links Ensembl NCBI GeneCards UniProt Show fit	kalirin RhoGEF kinase
chr12_+_12725897 Show fit	10.85	ENST00000326765.10	APOLD1 Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein L domain containing 1
chr11_-_114595777 Show fit	10.65	ENST00000375478.4	NXPE4 Links Ensembl NCBI GeneCards UniProt Show fit	neurexophilin and PC-esterase domain family member 4
chr11_-_114595750 Show fit	10.42	ENST00000424261.6	NXPE4 Links Ensembl NCBI GeneCards UniProt Show fit	neurexophilin and PC-esterase domain family member 4
chr19_+_49877694 Show fit	10.05	ENST00000221543.10	TBC1D17 Links Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 17
chr5_-_116536458 Show fit	9.74	ENST00000510263.5	SEMA6A Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6A
chr15_-_29822418 Show fit	9.73	ENST00000614355.5 ENST00000495972.6 ENST00000346128.10	TJP1 Links Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 1
chr15_+_43692886 Show fit	9.63	ENST00000434505.5 ENST00000411750.5	CKMT1A Links Ensembl NCBI GeneCards UniProt Show fit	creatine kinase, mitochondrial 1A
chr1_+_43389889 Show fit	9.61	ENST00000562955.2 ENST00000634258.3	SZT2 Links Ensembl NCBI GeneCards UniProt Show fit	SZT2 subunit of KICSTOR complex
chr4_-_86358487 Show fit	9.54	ENST00000641066.1 ENST00000512689.6 ENST00000641803.1 ENST00000640970.1 ENST00000641983.1	MAPK10 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 10
chr1_+_150257247 Show fit	9.30	ENST00000647854.1	CA14 Links Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 14
chr18_-_55635948 Show fit	9.24	ENST00000565124.4 ENST00000398339.5	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr5_-_108367860 Show fit	9.19	ENST00000496714.2	FBXL17 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and leucine rich repeat protein 17
chr1_+_162069674 Show fit	9.09	ENST00000361897.10	NOS1AP Links Ensembl NCBI GeneCards UniProt Show fit	nitric oxide synthase 1 adaptor protein
chr11_-_56292254 Show fit	8.95	ENST00000641600.1	OR8H1 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 8 subfamily H member 1
chr17_+_79778135 Show fit	8.92	ENST00000310942.9 ENST00000269399.5	CBX2 Links Ensembl NCBI GeneCards UniProt Show fit	chromobox 2
chr21_-_31558977 Show fit	8.85	ENST00000286827.7 ENST00000541036.5	TIAM1 Links Ensembl NCBI GeneCards UniProt Show fit	TIAM Rac1 associated GEF 1
chr7_+_20615653 Show fit	8.76	ENST00000404938.7	ABCB5 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily B member 5
chr10_+_110225955 Show fit	8.72	ENST00000239007.11	MXI1 Links Ensembl NCBI GeneCards UniProt Show fit	MAX interactor 1, dimerization protein
chr21_-_31160904 Show fit	8.70	ENST00000636887.1	TIAM1 Links Ensembl NCBI GeneCards UniProt Show fit	TIAM Rac1 associated GEF 1
chr15_+_43593054 Show fit	8.60	ENST00000453782.5 ENST00000300283.10 ENST00000437924.5	CKMT1B Links Ensembl NCBI GeneCards UniProt Show fit	creatine kinase, mitochondrial 1B
chr14_+_94110728 Show fit	8.56	ENST00000616764.4 ENST00000618863.1 ENST00000611954.4 ENST00000618200.4 ENST00000621160.4 ENST00000555819.5 ENST00000620396.4 ENST00000612813.4 ENST00000620066.1	IFI27 Links Ensembl NCBI GeneCards UniProt Show fit	interferon alpha inducible protein 27
chr19_-_40226682 Show fit	8.41	ENST00000430325.7 ENST00000599263.6	CCNP Links Ensembl NCBI GeneCards UniProt Show fit	cyclin P
chr2_-_112255015 Show fit	8.31	ENST00000615791.1 ENST00000409573.7 ENST00000272570.9	ZC3H8 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 8
chr12_-_12338674 Show fit	8.22	ENST00000545735.1	MANSC1 Links Ensembl NCBI GeneCards UniProt Show fit	MANSC domain containing 1
chr7_+_134866831 Show fit	8.21	ENST00000435928.1	CALD1 Links Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr14_+_70452161 Show fit	8.11	ENST00000603540.2	ADAM21 Links Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 21
chr6_-_46921926 Show fit	8.08	ENST00000283296.12	ADGRF5 Links Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor F5
chr4_-_185775271 Show fit	8.04	ENST00000430503.5 ENST00000319454.10 ENST00000450341.5	SORBS2 Links Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr11_+_46617521 Show fit	8.02	ENST00000580238.5 ENST00000581416.5 ENST00000529655.5 ENST00000533325.5 ENST00000683050.1 ENST00000581438.5 ENST00000583249.5 ENST00000530500.5 ENST00000526508.5 ENST00000578626.5 ENST00000577256.5 ENST00000524625.5 ENST00000582547.5 ENST00000359513.8 ENST00000528494.5	ATG13 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 13
chr4_-_89836213 Show fit	7.91	ENST00000618500.4 ENST00000508895.5	SNCA Links Ensembl NCBI GeneCards UniProt Show fit	synuclein alpha
chr2_+_235494024 Show fit	7.90	ENST00000304032.13 ENST00000409457.5 ENST00000336665.9	AGAP1 Links Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr10_+_91220603 Show fit	7.86	ENST00000336126.6	PCGF5 Links Ensembl NCBI GeneCards UniProt Show fit	polycomb group ring finger 5
chr3_+_159852933 Show fit	7.57	ENST00000482804.1	SCHIP1 Links Ensembl NCBI GeneCards UniProt Show fit	schwannomin interacting protein 1
chr3_-_139539577 Show fit	7.52	ENST00000619087.4	RBP1 Links Ensembl NCBI GeneCards UniProt Show fit	retinol binding protein 1
chr2_-_165204042 Show fit	7.50	ENST00000283254.12 ENST00000453007.1	SCN3A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 3
chr8_-_42843201 Show fit	7.40	ENST00000529779.1 ENST00000345117.2 ENST00000254250.7	THAP1 Links Ensembl NCBI GeneCards UniProt Show fit	THAP domain containing 1
chr17_+_3475959 Show fit	7.38	ENST00000263080.3	ASPA Links Ensembl NCBI GeneCards UniProt Show fit	aspartoacylase
chr2_-_2331225 Show fit	7.22	ENST00000648627.1 ENST00000649663.1 ENST00000650560.1 ENST00000428368.7 ENST00000648316.1 ENST00000648665.1 ENST00000649313.1 ENST00000399161.7 ENST00000647738.2	MYT1L Links Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr6_-_167157980 Show fit	7.14	ENST00000366834.2	GPR31 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 31
chr5_-_218136 Show fit	7.10	ENST00000296824.4	CCDC127 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 127
chr3_+_138348823 Show fit	7.07	ENST00000475711.5 ENST00000464896.5	MRAS Links Ensembl NCBI GeneCards UniProt Show fit	muscle RAS oncogene homolog
chr2_+_32277883 Show fit	6.93	ENST00000238831.9	YIPF4 Links Ensembl NCBI GeneCards UniProt Show fit	Yip1 domain family member 4
chr3_+_138349209 Show fit	6.92	ENST00000474559.1	MRAS Links Ensembl NCBI GeneCards UniProt Show fit	muscle RAS oncogene homolog
chr10_-_60141004 Show fit	6.79	ENST00000355288.6	ANK3 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin 3
chr6_+_32154131 Show fit	6.78	ENST00000375143.6 ENST00000324816.11 ENST00000424499.1	PPT2 Links Ensembl NCBI GeneCards UniProt Show fit	palmitoyl-protein thioesterase 2
chr4_+_123399488 Show fit	6.74	ENST00000394339.2	SPRY1 Links Ensembl NCBI GeneCards UniProt Show fit	sprouty RTK signaling antagonist 1
chr5_-_134371004 Show fit	6.74	ENST00000521755.1 ENST00000523054.5 ENST00000518409.1	CDKL3 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000273345.5 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase like 3 novel transcript
chr2_-_165203870 Show fit	6.71	ENST00000639244.1 ENST00000409101.7 ENST00000668657.1	SCN3A Links Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 3
chr12_-_10098977 Show fit	6.70	ENST00000315330.8 ENST00000457018.6	CLEC1A Links Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 1 member A
chr19_+_41262656 Show fit	6.68	ENST00000599719.5 ENST00000601309.5	HNRNPUL1 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein U like 1
chr9_+_27109200 Show fit	6.59	ENST00000380036.10	TEK Links Ensembl NCBI GeneCards UniProt Show fit	TEK receptor tyrosine kinase
chr10_-_50885619 Show fit	6.49	ENST00000373997.8	A1CF Links Ensembl NCBI GeneCards UniProt Show fit	APOBEC1 complementation factor
chr14_-_75051426 Show fit	6.46	ENST00000556257.5 ENST00000355774.7 ENST00000557648.1 ENST00000553263.1 ENST00000380968.6	MLH3 Links Ensembl NCBI GeneCards UniProt Show fit	mutL homolog 3
chr4_+_87832917 Show fit	6.32	ENST00000395102.8 ENST00000497649.6 ENST00000540395.1 ENST00000560249.5 ENST00000511670.5 ENST00000361056.3	MEPE Links Ensembl NCBI GeneCards UniProt Show fit	matrix extracellular phosphoglycoprotein
chr4_-_185775890 Show fit	6.18	ENST00000437304.6	SORBS2 Links Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr11_-_66907891 Show fit	6.14	ENST00000393955.6	PC Links Ensembl NCBI GeneCards UniProt Show fit	pyruvate carboxylase
chr17_-_8118489 Show fit	6.13	ENST00000380149.6 ENST00000448843.7	ALOXE3 Links Ensembl NCBI GeneCards UniProt Show fit	arachidonate lipoxygenase 3
chr19_-_58150772 Show fit	6.09	ENST00000597186.5 ENST00000598312.6	ZNF329 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 329
chr8_-_71547626 Show fit	6.07	ENST00000647540.1 ENST00000644229.1	EYA1 Links Ensembl NCBI GeneCards UniProt Show fit	EYA transcriptional coactivator and phosphatase 1
chr9_+_27109135 Show fit	6.06	ENST00000519097.5 ENST00000615002.4	TEK Links Ensembl NCBI GeneCards UniProt Show fit	TEK receptor tyrosine kinase
chr7_-_712437 Show fit	6.04	ENST00000360274.8	PRKAR1B Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit beta
chr6_+_122789197 Show fit	6.01	ENST00000368440.5	SMPDL3A Links Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase acid like 3A
chr19_+_15049469 Show fit	5.99	ENST00000427043.4	CASP14 Links Ensembl NCBI GeneCards UniProt Show fit	caspase 14
chr11_+_57598184 Show fit	5.98	ENST00000677625.1 ENST00000676670.1	SERPING1 Links Ensembl NCBI GeneCards UniProt Show fit	serpin family G member 1
chr1_-_2003780 Show fit	5.89	ENST00000682832.1	CFAP74 Links Ensembl NCBI GeneCards UniProt Show fit	cilia and flagella associated protein 74
chr18_+_34493428 Show fit	5.86	ENST00000682483.1	DTNA Links Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin alpha
chr9_+_27109393 Show fit	5.83	ENST00000406359.8	TEK Links Ensembl NCBI GeneCards UniProt Show fit	TEK receptor tyrosine kinase
chr11_+_57597563 Show fit	5.81	ENST00000619430.2 ENST00000457869.1 ENST00000340687.10 ENST00000278407.9 ENST00000378323.8 ENST00000378324.6 ENST00000403558.1	SERPING1 Links Ensembl NCBI GeneCards UniProt Show fit	serpin family G member 1
chr1_+_151766655 Show fit	5.78	ENST00000400999.7	OAZ3 Links Ensembl NCBI GeneCards UniProt Show fit	ornithine decarboxylase antizyme 3
chr3_+_148730100 Show fit	5.77	ENST00000474935.5 ENST00000475347.5 ENST00000461609.1	AGTR1 Links Ensembl NCBI GeneCards UniProt Show fit	angiotensin II receptor type 1
chr10_-_50885656 Show fit	5.70	ENST00000374001.6 ENST00000395489.6 ENST00000282641.6 ENST00000395495.5 ENST00000373995.7 ENST00000414883.1	A1CF Links Ensembl NCBI GeneCards UniProt Show fit	APOBEC1 complementation factor
chr16_-_4273014 Show fit	5.68	ENST00000204517.11	TFAP4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor AP-4
chr2_+_174395721 Show fit	5.63	ENST00000272732.11 ENST00000458563.5 ENST00000409673.7 ENST00000435964.1 ENST00000424069.5 ENST00000427038.5	SCRN3 Links Ensembl NCBI GeneCards UniProt Show fit	secernin 3
chr2_+_65056382 Show fit	5.54	ENST00000377990.7 ENST00000537589.1 ENST00000260569.4	CEP68 Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 68
chr15_-_55365231 Show fit	5.54	ENST00000568543.1	CCPG1 Links Ensembl NCBI GeneCards UniProt Show fit	cell cycle progression 1
chr2_+_227616998 Show fit	5.44	ENST00000641801.1	SCYGR4 Links Ensembl NCBI GeneCards UniProt Show fit	small cysteine and glycine repeat containing 4
chr10_-_60572599 Show fit	5.34	ENST00000503366.5	ANK3 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin 3
chr6_+_32154010 Show fit	5.32	ENST00000375137.6	PPT2 Links Ensembl NCBI GeneCards UniProt Show fit	palmitoyl-protein thioesterase 2
chr19_+_1205761 Show fit	5.30	ENST00000326873.12 ENST00000586243.5	STK11 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 11
chr11_+_112961247 Show fit	5.25	ENST00000621518.4 ENST00000618266.4 ENST00000615112.4 ENST00000615285.4 ENST00000619839.4 ENST00000401611.6 ENST00000621128.4	NCAM1 Links Ensembl NCBI GeneCards UniProt Show fit	neural cell adhesion molecule 1
chr9_-_15472732 Show fit	5.20	ENST00000481862.1	PSIP1 Links Ensembl NCBI GeneCards UniProt Show fit	PC4 and SFRS1 interacting protein 1
chr5_-_10307821 Show fit	5.20	ENST00000296658.4	CMBL Links Ensembl NCBI GeneCards UniProt Show fit	carboxymethylenebutenolidase homolog
chr16_+_1680337 Show fit	5.17	ENST00000566691.5 ENST00000382710.8	JPT2 Links Ensembl NCBI GeneCards UniProt Show fit	Jupiter microtubule associated homolog 2
chr10_+_80413817 Show fit	5.11	ENST00000372187.9	PRXL2A Links Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin like 2A
chr3_-_186109067 Show fit	5.09	ENST00000306376.10	ETV5 Links Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 5
chr10_+_122163590 Show fit	5.08	ENST00000368999.5	TACC2 Links Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr1_+_110210272 Show fit	5.04	ENST00000438661.3	KCNC4 Links Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily C member 4
chr13_-_98977975 Show fit	4.99	ENST00000376460.5	DOCK9 Links Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 9
chr7_+_106865263 Show fit	4.87	ENST00000440650.6 ENST00000496166.6 ENST00000473541.5	PIK3CG Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr15_-_58279245 Show fit	4.87	ENST00000558231.5	ALDH1A2 Links Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family member A2
chr18_+_34493386 Show fit	4.85	ENST00000679936.1	DTNA Links Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin alpha
chr4_+_95051671 Show fit	4.70	ENST00000440890.7	BMPR1B Links Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein receptor type 1B
chr2_-_182866627 Show fit	4.69	ENST00000295113.5	FRZB Links Ensembl NCBI GeneCards UniProt Show fit	frizzled related protein
chr11_-_94493798 Show fit	4.67	ENST00000538923.1 ENST00000540013.5 ENST00000407439.7 ENST00000323929.8 ENST00000393241.8	MRE11 Links Ensembl NCBI GeneCards UniProt Show fit	MRE11 homolog, double strand break repair nuclease
chr3_-_45884685 Show fit	4.63	ENST00000684620.1	LZTFL1 Links Ensembl NCBI GeneCards UniProt Show fit	leucine zipper transcription factor like 1
chr13_-_98978022 Show fit	4.59	ENST00000682017.1 ENST00000442173.5 ENST00000627024.2	DOCK9 Links Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 9
chr11_+_77821105 Show fit	4.43	ENST00000532481.5	AAMDC Links Ensembl NCBI GeneCards UniProt Show fit	adipogenesis associated Mth938 domain containing
chr4_-_89835617 Show fit	4.40	ENST00000611107.1 ENST00000345009.8 ENST00000505199.5 ENST00000502987.5	SNCA Links Ensembl NCBI GeneCards UniProt Show fit	synuclein alpha
chr8_-_42768781 Show fit	4.33	ENST00000276410.7	CHRNA6 Links Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor nicotinic alpha 6 subunit
chr5_-_131796965 Show fit	4.32	ENST00000514667.1 ENST00000511848.1 ENST00000510461.6	ENSG00000273217.1 Links Ensembl NCBI GeneCards UniProt Show fit FNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein folliculin interacting protein 1
chr5_+_80407994 Show fit	4.28	ENST00000338008.9 ENST00000510158.5	ZFYVE16 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger FYVE-type containing 16
chr17_-_42745025 Show fit	4.24	ENST00000592492.5 ENST00000585893.5 ENST00000593214.5 ENST00000590078.5 ENST00000428826.7 ENST00000586382.5 ENST00000415827.6 ENST00000592743.5 ENST00000586089.5	EZH1 Links Ensembl NCBI GeneCards UniProt Show fit	enhancer of zeste 1 polycomb repressive complex 2 subunit
chr18_+_62715526 Show fit	4.23	ENST00000262719.10	PHLPP1 Links Ensembl NCBI GeneCards UniProt Show fit	PH domain and leucine rich repeat protein phosphatase 1
chr1_-_153541765 Show fit	4.22	ENST00000368718.5	S100A5 Links Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A5
chr7_-_13988863 Show fit	4.22	ENST00000405358.8	ETV1 Links Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chr1_-_56966006 Show fit	4.19	ENST00000371237.9	C8B Links Ensembl NCBI GeneCards UniProt Show fit	complement C8 beta chain
chr5_+_80408031 Show fit	4.15	ENST00000505560.5 ENST00000509562.2	ZFYVE16 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger FYVE-type containing 16
chr4_-_152411734 Show fit	3.99	ENST00000603841.1	FBXW7 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 7
chr2_+_156436345 Show fit	3.96	ENST00000438166.7	GPD2 Links Ensembl NCBI GeneCards UniProt Show fit	glycerol-3-phosphate dehydrogenase 2
chr7_-_95596507 Show fit	3.88	ENST00000005178.6	PDK4 Links Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehydrogenase kinase 4
chr4_-_69961007 Show fit	3.84	ENST00000353151.3	CSN2 Links Ensembl NCBI GeneCards UniProt Show fit	casein beta
chr14_-_99272184 Show fit	3.78	ENST00000357195.8	BCL11B Links Ensembl NCBI GeneCards UniProt Show fit	BAF chromatin remodeling complex subunit BCL11B
chr14_-_70809494 Show fit	3.77	ENST00000381250.8 ENST00000554752.7 ENST00000555993.6	MAP3K9 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 9
chr3_-_46566276 Show fit	3.77	ENST00000395905.8	LRRC2 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 2
chr20_-_46364385 Show fit	3.71	ENST00000243896.6 ENST00000543605.5 ENST00000372230.10 ENST00000317734.12	SLC35C2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 member C2
chr2_+_172556039 Show fit	3.70	ENST00000410055.5 ENST00000282077.8	PDK1 Links Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehydrogenase kinase 1
chr13_+_97434154 Show fit	3.68	ENST00000245304.5	RAP2A Links Ensembl NCBI GeneCards UniProt Show fit	RAP2A, member of RAS oncogene family
chr3_+_108296489 Show fit	3.68	ENST00000619531.4	HHLA2 Links Ensembl NCBI GeneCards UniProt Show fit	HERV-H LTR-associating 2
chr1_+_96722628 Show fit	3.61	ENST00000675401.1	PTBP2 Links Ensembl NCBI GeneCards UniProt Show fit	polypyrimidine tract binding protein 2
chr10_+_97640686 Show fit	3.60	ENST00000370631.3	PI4K2A Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol 4-kinase type 2 alpha
chr17_+_74431338 Show fit	3.60	ENST00000342648.9 ENST00000652232.1 ENST00000481232.2	GPRC5C Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor class C group 5 member C
chr5_-_126595185 Show fit	3.59	ENST00000510111.6 ENST00000635851.1 ENST00000637964.1 ENST00000413020.6 ENST00000637782.1 ENST00000409134.8 ENST00000637272.1 ENST00000636879.1 ENST00000636743.1 ENST00000636886.1 ENST00000509270.2	ALDH7A1 Links Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 7 family member A1
chr1_-_168137430 Show fit	3.50	ENST00000546300.5 ENST00000271357.9 ENST00000367835.1 ENST00000537209.5	GPR161 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 161
chr2_-_36966503 Show fit	3.48	ENST00000263918.9	STRN Links Ensembl NCBI GeneCards UniProt Show fit	striatin
chr8_-_42768602 Show fit	3.45	ENST00000534622.5	CHRNA6 Links Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor nicotinic alpha 6 subunit
chr7_-_38349972 Show fit	3.39	ENST00000390344.2	TRGV5 Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor gamma variable 5
chr10_+_122163672 Show fit	3.33	ENST00000369004.7 ENST00000260733.7	TACC2 Links Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr12_-_70637405 Show fit	3.29	ENST00000548122.2 ENST00000551525.5 ENST00000550358.5 ENST00000334414.11	PTPRB Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type B
chr11_-_5269933 Show fit	3.29	ENST00000396895.3	HBE1 Links Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit epsilon 1
chr7_+_135148041 Show fit	3.21	ENST00000275767.3	TMEM140 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 140
chr7_+_106865474 Show fit	3.18	ENST00000359195.3	PIK3CG Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr8_-_40897814 Show fit	3.11	ENST00000297737.11 ENST00000315769.11	ZMAT4 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger matrin-type 4
chr17_-_69141878 Show fit	3.09	ENST00000590645.1 ENST00000284425.7	ABCA6 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 6
chr18_-_55402187 Show fit	3.09	ENST00000630268.2 ENST00000570177.6	TCF4 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr7_+_99828010 Show fit	2.96	ENST00000631161.2 ENST00000354829.7 ENST00000342499.8 ENST00000417625.5 ENST00000415413.5 ENST00000444905.5 ENST00000222382.5 ENST00000312017.9	CYP3A43 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 3 subfamily A member 43
chr10_+_122163426 Show fit	2.88	ENST00000360561.7	TACC2 Links Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr9_+_706841 Show fit	2.88	ENST00000382293.7	KANK1 Links Ensembl NCBI GeneCards UniProt Show fit	KN motif and ankyrin repeat domains 1
chr8_-_53843228 Show fit	2.83	ENST00000359530.7	ATP6V1H Links Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting V1 subunit H
chr6_-_117425855 Show fit	2.81	ENST00000368508.7	ROS1 Links Ensembl NCBI GeneCards UniProt Show fit	ROS proto-oncogene 1, receptor tyrosine kinase
chr15_-_30991415 Show fit	2.76	ENST00000563714.5	MTMR10 Links Ensembl NCBI GeneCards UniProt Show fit	myotubularin related protein 10
chrX_-_149595314 Show fit	2.74	ENST00000598963.3	HSFX2 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock transcription factor family, X-linked 2
chr16_+_28846674 Show fit	2.74	ENST00000322610.12	SH2B1 Links Ensembl NCBI GeneCards UniProt Show fit	SH2B adaptor protein 1
chr4_-_108166715 Show fit	2.69	ENST00000510624.5	LEF1 Links Ensembl NCBI GeneCards UniProt Show fit	lymphoid enhancer binding factor 1
chr9_+_5510492 Show fit	2.67	ENST00000397747.5	PDCD1LG2 Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 1 ligand 2
chr1_-_227318125 Show fit	2.66	ENST00000366764.7	CDC42BPA Links Ensembl NCBI GeneCards UniProt Show fit	CDC42 binding protein kinase alpha
chr8_+_119067239 Show fit	2.64	ENST00000332843.3	COLEC10 Links Ensembl NCBI GeneCards UniProt Show fit	collectin subfamily member 10
chr1_+_160796157 Show fit	2.64	ENST00000263285.11 ENST00000368039.2	LY9 Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 9
chr10_+_110207587 Show fit	2.62	ENST00000332674.9 ENST00000453116.5	MXI1 Links Ensembl NCBI GeneCards UniProt Show fit	MAX interactor 1, dimerization protein
chr10_-_1200360 Show fit	2.59	ENST00000381310.7 ENST00000381305.1	ADARB2 Links Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase RNA specific B2 (inactive)
chr11_-_123741614 Show fit	2.57	ENST00000526252.5 ENST00000530393.6 ENST00000533463.5 ENST00000336139.8 ENST00000529691.1 ENST00000528306.5	ZNF202 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 202
chr1_-_56966133 Show fit	2.54	ENST00000535057.5 ENST00000543257.5	C8B Links Ensembl NCBI GeneCards UniProt Show fit	complement C8 beta chain
chr8_-_86743626 Show fit	2.54	ENST00000320005.6	CNGB3 Links Ensembl NCBI GeneCards UniProt Show fit	cyclic nucleotide gated channel subunit beta 3
chr20_-_44521989 Show fit	2.53	ENST00000342374.5 ENST00000255175.5	SERINC3 Links Ensembl NCBI GeneCards UniProt Show fit	serine incorporator 3
chr12_-_102478539 Show fit	2.53	ENST00000424202.6	IGF1 Links Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr14_-_92106535 Show fit	2.53	ENST00000526872.3 ENST00000532032.5 ENST00000506466.5 ENST00000554592.5 ENST00000555381.5 ENST00000553491.5 ENST00000556220.5 ENST00000557311.6 ENST00000617719.4 ENST00000554672.6 ENST00000644486.2 ENST00000502250.5 ENST00000503767.5	ATXN3 Links Ensembl NCBI GeneCards UniProt Show fit	ataxin 3
chr16_+_77199408 Show fit	2.51	ENST00000378644.5	SYCE1L Links Ensembl NCBI GeneCards UniProt Show fit	synaptonemal complex central element protein 1 like

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.1	72.5	GO:0006542	glutamine biosynthetic process(GO:0006542)
12.0	60.1	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
7.7	31.0	GO:1903294	regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
5.3	21.3	GO:1903116	positive regulation of actin filament-based movement(GO:1903116) positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
5.0	20.0	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
4.5	13.4	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
4.4	17.5	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
4.2	12.6	GO:0044565	dendritic cell proliferation(GO:0044565)
3.9	11.8	GO:0001868	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
3.8	30.2	GO:0001887	selenium compound metabolic process(GO:0001887)
3.6	21.8	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
3.4	23.8	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
3.0	12.1	GO:0072658	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.8	28.2	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
2.5	7.4	GO:0006533	aspartate catabolic process(GO:0006533)
2.1	12.3	GO:0051945	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
2.0	12.2	GO:0016554	cytidine to uridine editing(GO:0016554)
1.9	9.7	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
1.9	5.8	GO:0015847	putrescine transport(GO:0015847)
1.9	22.6	GO:0008354	germ cell migration(GO:0008354)
1.8	14.5	GO:0048014	Tie signaling pathway(GO:0048014)
1.8	5.3	GO:0097534	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
1.7	6.7	GO:0060940	epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.7	8.3	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.5	4.6	GO:1903567	negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
1.5	6.1	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.4	5.8	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
1.4	10.8	GO:0042118	endothelial cell activation(GO:0042118)
1.4	14.9	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
1.3	8.0	GO:0032252	negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
1.3	14.7	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
1.3	23.1	GO:0034389	lipid particle organization(GO:0034389)
1.3	3.8	GO:1903487	regulation of lactation(GO:1903487)
1.2	11.0	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
1.2	3.6	GO:0031455	glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
1.2	5.8	GO:0006127	glycerophosphate shuttle(GO:0006127)
1.1	12.1	GO:0098734	macromolecule depalmitoylation(GO:0098734)
1.1	18.1	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.0	4.0	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
1.0	4.0	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.9	12.4	GO:0006776	vitamin A metabolic process(GO:0006776)
0.9	33.4	GO:0048665	neuron fate specification(GO:0048665)
0.8	11.8	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.8	64.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.8	4.7	GO:0010966	regulation of phosphate transport(GO:0010966)
0.8	4.7	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
0.8	6.1	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.8	2.3	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.7	9.6	GO:0006600	creatine metabolic process(GO:0006600)
0.7	3.7	GO:0071895	odontoblast differentiation(GO:0071895)
0.7	8.1	GO:0043129	surfactant homeostasis(GO:0043129) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.7	18.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.7	2.9	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.7	8.8	GO:0042908	xenobiotic transport(GO:0042908)
0.7	4.7	GO:0001550	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.7	2.0	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.7	5.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.6	9.5	GO:0007258	JUN phosphorylation(GO:0007258)
0.6	1.8	GO:0033082	regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.6	9.0	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.6	1.7	GO:0046603	negative regulation of mitotic centrosome separation(GO:0046603)
0.6	5.5	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5	6.0	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.5	4.2	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.5	9.7	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.5	2.5	GO:1904075	regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.5	1.4	GO:0072709	cellular response to sorbitol(GO:0072709)
0.5	3.8	GO:0007256	activation of JNKK activity(GO:0007256)
0.5	3.7	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.4	5.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.4	4.2	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.4	14.2	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.4	15.4	GO:0006783	heme biosynthetic process(GO:0006783)
0.4	3.7	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.4	17.6	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.4	6.0	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.4	34.8	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.3	11.3	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.3	15.7	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.3	2.3	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.3	2.5	GO:0009597	detection of virus(GO:0009597)
0.3	5.7	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.3	1.6	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.3	0.9	GO:1902617	response to fluoride(GO:1902617)
0.3	6.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.3	2.7	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.3	16.1	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.3	4.7	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.3	3.9	GO:0050812	regulation of acyl-CoA biosynthetic process(GO:0050812)
0.2	6.5	GO:0098780	response to mitochondrial depolarisation(GO:0098780)
0.2	11.4	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.2	12.7	GO:0019228	neuronal action potential(GO:0019228)
0.2	3.5	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2	0.7	GO:0071486	response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.2	8.4	GO:0006622	protein targeting to lysosome(GO:0006622)
0.2	2.6	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.2	8.5	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.2	0.6	GO:0097114	NMDA glutamate receptor clustering(GO:0097114)
0.2	1.8	GO:1904424	regulation of GTP binding(GO:1904424)
0.2	1.2	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
0.2	4.2	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2	14.9	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.2	8.6	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.2	4.2	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.2	3.3	GO:0015671	oxygen transport(GO:0015671)
0.2	9.3	GO:0015701	bicarbonate transport(GO:0015701)
0.2	5.9	GO:0035082	axoneme assembly(GO:0035082)
0.1	5.2	GO:0030517	negative regulation of axon extension(GO:0030517)
0.1	0.4	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.1	3.6	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.1	7.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	3.7	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.1	0.3	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1	1.8	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.1	0.9	GO:0006828	manganese ion transport(GO:0006828)
0.1	0.8	GO:0018344	protein geranylgeranylation(GO:0018344)
0.1	2.8	GO:0007035	vacuolar acidification(GO:0007035) energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) phagosome acidification(GO:0090383)
0.1	9.0	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1	11.3	GO:0021987	cerebral cortex development(GO:0021987)
0.1	5.0	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.1	0.6	GO:0060044	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1	0.4	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
0.1	1.9	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.1	9.3	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1	0.7	GO:1903944	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	15.8	GO:0006469	negative regulation of protein kinase activity(GO:0006469)
0.1	1.0	GO:1901663	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	2.4	GO:0046850	regulation of bone remodeling(GO:0046850)
0.1	0.8	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.1	0.4	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.9	GO:0097264	self proteolysis(GO:0097264)
0.0	11.8	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	1.6	GO:0035456	response to interferon-beta(GO:0035456)
0.0	5.3	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	4.3	GO:0001935	endothelial cell proliferation(GO:0001935)
0.0	2.1	GO:0007632	visual behavior(GO:0007632)
0.0	0.2	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0	0.8	GO:0007635	chemosensory behavior(GO:0007635)
0.0	1.1	GO:0042438	melanin biosynthetic process(GO:0042438)
0.0	3.1	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	1.7	GO:0016486	peptide hormone processing(GO:0016486)
0.0	3.6	GO:0070268	cornification(GO:0070268)
0.0	0.7	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0	0.7	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.6	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	1.2	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.0	0.2	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.3	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	2.4	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	1.1	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	4.5	GO:0009615	response to virus(GO:0009615)
0.0	0.9	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	2.5	GO:0007601	visual perception(GO:0007601)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.1	30.6	GO:0048787	presynaptic active zone membrane(GO:0048787)
4.3	21.3	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
3.0	12.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
2.7	8.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
2.7	13.4	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
2.6	72.5	GO:0097386	glial cell projection(GO:0097386)
2.2	28.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
2.1	8.3	GO:0035363	histone locus body(GO:0035363)
1.8	5.3	GO:0036398	TCR signalosome(GO:0036398)
1.5	30.2	GO:0031089	platelet dense granule lumen(GO:0031089)
1.4	9.6	GO:1990130	Iml1 complex(GO:1990130)
1.3	8.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
1.3	6.5	GO:0005712	chiasma(GO:0005712)
1.0	5.8	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.8	6.7	GO:0005579	membrane attack complex(GO:0005579)
0.7	3.6	GO:0035838	growing cell tip(GO:0035838)
0.7	2.8	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.7	17.5	GO:0044295	axonal growth cone(GO:0044295)
0.7	12.1	GO:0043194	axon initial segment(GO:0043194)
0.6	3.7	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.6	14.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.6	4.0	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.6	8.9	GO:0035102	PRC1 complex(GO:0035102)
0.5	8.2	GO:0030478	actin cap(GO:0030478)
0.5	38.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.5	38.6	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4	12.3	GO:0005640	nuclear outer membrane(GO:0005640)
0.4	4.7	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.4	15.5	GO:0009925	basal plasma membrane(GO:0009925)
0.4	32.9	GO:0005776	autophagosome(GO:0005776)
0.3	9.7	GO:0005921	gap junction(GO:0005921)
0.3	11.8	GO:0032839	dendrite cytoplasm(GO:0032839)
0.3	22.9	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3	6.0	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.3	7.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.3	3.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3	43.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.2	2.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	5.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.2	1.9	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2	11.9	GO:0031519	PcG protein complex(GO:0031519)
0.2	15.7	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	4.0	GO:0042405	nuclear inclusion body(GO:0042405)
0.2	48.2	GO:0005802	trans-Golgi network(GO:0005802)
0.2	3.3	GO:0005833	hemoglobin complex(GO:0005833)
0.2	3.7	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.2	0.8	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2	2.3	GO:0030870	Mre11 complex(GO:0030870)
0.2	24.4	GO:0017053	transcriptional repressor complex(GO:0017053)
0.2	2.4	GO:0042589	zymogen granule membrane(GO:0042589)
0.1	1.5	GO:0016013	syntrophin complex(GO:0016013)
0.1	21.7	GO:0030426	growth cone(GO:0030426)
0.1	18.4	GO:0032993	protein-DNA complex(GO:0032993)
0.1	16.3	GO:0005923	bicellular tight junction(GO:0005923)
0.1	3.7	GO:0005801	cis-Golgi network(GO:0005801)
0.1	14.5	GO:0030018	Z disc(GO:0030018)
0.1	1.8	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.1	13.1	GO:0043209	myelin sheath(GO:0043209)
0.1	2.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	9.8	GO:0042383	sarcolemma(GO:0042383)
0.1	2.5	GO:0000795	synaptonemal complex(GO:0000795)
0.1	4.4	GO:0055037	recycling endosome(GO:0055037)
0.1	7.3	GO:0031901	early endosome membrane(GO:0031901)
0.1	0.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	8.9	GO:0043202	lysosomal lumen(GO:0043202)
0.0	3.3	GO:0035579	specific granule membrane(GO:0035579)
0.0	0.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	5.0	GO:0043679	axon terminus(GO:0043679)
0.0	1.9	GO:0045095	keratin filament(GO:0045095)
0.0	19.2	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	7.4	GO:0001650	fibrillar center(GO:0001650)
0.0	8.6	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.7	GO:0097342	ripoptosome(GO:0097342)
0.0	1.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	2.6	GO:0005581	collagen trimer(GO:0005581)
0.0	1.7	GO:0005871	kinesin complex(GO:0005871)
0.0	1.1	GO:0016592	mediator complex(GO:0016592)
0.0	6.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	2.2	GO:0005875	microtubule associated complex(GO:0005875)
0.0	1.6	GO:0005796	Golgi lumen(GO:0005796)
0.0	6.0	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	3.3	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.1	GO:0034657	GID complex(GO:0034657)
0.0	4.1	GO:0030424	axon(GO:0030424)
0.0	3.1	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	5.6	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	4.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	17.4	GO:0005887	integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.1	72.5	GO:0016211	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
15.0	60.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
5.0	20.0	GO:0097001	ceramide binding(GO:0097001)
3.9	31.4	GO:0004111	creatine kinase activity(GO:0004111)
3.8	22.6	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
2.7	13.4	GO:0030348	syntaxin-3 binding(GO:0030348)
2.5	30.2	GO:0008430	selenium binding(GO:0008430)
2.1	12.3	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
1.9	5.8	GO:0015489	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
1.9	5.8	GO:0001596	angiotensin type I receptor activity(GO:0001596)
1.8	8.8	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
1.6	6.3	GO:1990430	extracellular matrix protein binding(GO:1990430)
1.6	18.7	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.5	30.6	GO:0043274	phospholipase binding(GO:0043274)
1.4	5.8	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
1.3	11.8	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
1.3	7.6	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.2	7.4	GO:0004046	aminoacylase activity(GO:0004046)
1.2	6.1	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
1.2	36.8	GO:0005521	lamin binding(GO:0005521)
1.2	3.6	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
1.1	23.7	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
1.1	12.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.0	15.7	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.9	3.8	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.9	28.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.9	8.7	GO:0005549	odorant binding(GO:0005549)
0.8	8.3	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.8	6.5	GO:0019237	centromeric DNA binding(GO:0019237)
0.8	18.6	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.8	12.4	GO:0016918	retinal binding(GO:0016918)
0.8	21.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.7	9.5	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.7	6.0	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.6	6.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.6	12.3	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5	9.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.5	6.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.5	14.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.5	4.0	GO:0050816	phosphothreonine binding(GO:0050816)
0.5	3.3	GO:0030492	hemoglobin binding(GO:0030492)
0.4	14.2	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4	2.5	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.4	5.2	GO:0097100	supercoiled DNA binding(GO:0097100)
0.4	14.7	GO:0043015	gamma-tubulin binding(GO:0043015)
0.4	4.7	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.4	14.0	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.4	2.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.3	6.7	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3	8.2	GO:0005523	tropomyosin binding(GO:0005523)
0.3	1.2	GO:0042015	interleukin-20 binding(GO:0042015)
0.3	4.0	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.3	7.8	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.3	51.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3	5.6	GO:0016805	dipeptidase activity(GO:0016805)
0.2	16.1	GO:0030276	clathrin binding(GO:0030276)
0.2	5.3	GO:0030275	LRR domain binding(GO:0030275)
0.2	1.7	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2	2.5	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2	12.1	GO:0030507	spectrin binding(GO:0030507)
0.2	69.9	GO:0008022	protein C-terminus binding(GO:0008022)
0.2	4.7	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.2	8.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2	17.4	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.2	2.1	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.2	2.6	GO:0004000	adenosine deaminase activity(GO:0004000)
0.2	2.4	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.9	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.4	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.1	5.7	GO:0070888	E-box binding(GO:0070888)
0.1	3.0	GO:0070330	aromatase activity(GO:0070330)
0.1	2.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.7	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	2.6	GO:0005537	mannose binding(GO:0005537)
0.1	2.8	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	8.9	GO:0035064	methylated histone binding(GO:0035064)
0.1	12.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	18.9	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	12.2	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	3.3	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	8.7	GO:0030165	PDZ domain binding(GO:0030165)
0.1	2.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	4.4	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.1	3.6	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	8.1	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1	0.8	GO:0033038	bitter taste receptor activity(GO:0033038)
0.1	11.3	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.1	1.4	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	0.6	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	3.8	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1	4.2	GO:0005507	copper ion binding(GO:0005507)
0.1	2.5	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	1.0	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	5.3	GO:0001618	virus receptor activity(GO:0001618)
0.0	3.1	GO:0019003	GDP binding(GO:0019003)
0.0	22.7	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	9.5	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	1.8	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	3.5	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	1.5	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	1.0	GO:0043531	ADP binding(GO:0043531)
0.0	2.8	GO:0005179	hormone activity(GO:0005179)
0.0	2.7	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.7	GO:0005123	death receptor binding(GO:0005123)
0.0	3.2	GO:0005516	calmodulin binding(GO:0005516)
0.0	1.1	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	28.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.7	15.7	PID S1P S1P4 PATHWAY	S1P4 pathway
0.5	3.6	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.3	20.9	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.3	12.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.2	9.7	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.2	8.0	PID EPHA FWDPATHWAY	EPHA forward signaling
0.2	7.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.2	8.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.2	8.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.2	9.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	1.4	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.1	10.0	PID SHP2 PATHWAY	SHP2 signaling
0.1	3.3	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	4.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	10.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	5.8	PID ARF6 PATHWAY	Arf6 signaling events
0.1	8.0	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	14.7	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	6.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	5.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	6.4	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	3.8	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	8.8	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	5.3	PID FGF PATHWAY	FGF signaling pathway
0.1	17.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	5.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	0.4	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	1.6	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	10.4	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	0.9	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	2.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	2.7	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	2.2	PID LKB1 PATHWAY	LKB1 signaling events
0.0	9.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	2.1	PID CDC42 PATHWAY	CDC42 signaling events
0.0	3.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	72.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
2.0	43.9	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.3	8.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.6	9.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.6	28.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.5	11.8	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.5	5.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.4	7.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4	12.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.4	4.9	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	28.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.4	9.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.4	15.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4	9.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.4	7.8	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.4	9.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	11.8	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.3	2.4	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.3	12.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.3	11.9	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.2	6.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.2	9.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	9.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	13.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	6.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.2	6.0	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.2	6.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.2	3.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	8.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.6	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	5.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	2.8	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1	11.4	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	2.7	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	9.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.1	10.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	8.8	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.8	REACTOME OPSINS	Genes involved in Opsins
0.1	3.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	2.2	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	3.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	23.5	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.1	2.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	2.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	3.0	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	10.0	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	7.1	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling