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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for GGCAAGA
Z-value: 0.34
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miRNA associated with seed GGCAAGA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-31-5p
|
MIMAT0000089 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GGCAAGA
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_42144823 Show fit | 3.82 |
ENST00000398675.8
|
glucoside xylosyltransferase 1 |
|
| chr1_-_40665654 Show fit | 3.27 |
ENST00000372684.8
|
regulating synaptic membrane exocytosis 3 |
|
| chr5_+_31639104 Show fit | 3.13 |
ENST00000438447.2
|
PDZ domain containing 2 |
|
| chr2_-_9003657 Show fit | 3.08 |
ENST00000462696.1
ENST00000305997.8 |
membrane bound O-acyltransferase domain containing 2 |
|
| chr17_-_28951285 Show fit | 2.95 |
ENST00000577226.5
|
PHD finger protein 12 |
|
| chr17_-_1628808 Show fit | 2.92 |
ENST00000301335.10
|
solute carrier family 43 member 2 |
|
| chr3_-_133895867 Show fit | 2.91 |
ENST00000285208.9
|
RAB6B, member RAS oncogene family |
|
| chr16_+_58249910 Show fit | 2.62 |
ENST00000219299.8
ENST00000443128.6 ENST00000616795.1 |
coiled-coil domain containing 113 |
|
| chr3_-_185498964 Show fit | 2.42 |
ENST00000296254.3
|
transmembrane protein 41A |
|
| chr7_-_35695120 Show fit | 2.41 |
ENST00000311350.8
ENST00000396081.5 |
HERPUD family member 2 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.5 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.1 | 4.5 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 3.8 | GO:1902475 | L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.1 | 3.1 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.0 | 3.1 | GO:0060271 | cilium morphogenesis(GO:0060271) |
| 0.1 | 2.9 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.2 | 2.3 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.1 | 2.2 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.1 | 2.1 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.7 | 2.0 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.8 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 3.0 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 2.9 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 2.6 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 2.5 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 2.4 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.2 | 2.2 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.0 | 2.1 | GO:0031461 | cullin-RING ubiquitin ligase complex(GO:0031461) |
| 0.3 | 2.0 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.1 | 2.0 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.8 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.0 | 3.2 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.3 | 3.1 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.2 | 3.0 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.1 | 2.9 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.0 | 2.5 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.2 | 2.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 2.2 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 2.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 2.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.7 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 2.5 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 2.2 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.5 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 1.4 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.3 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 1.2 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 1.1 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 1.0 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 1.0 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.1 | 2.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 2.7 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 2.1 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 2.0 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 2.0 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 1.8 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 1.7 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 1.4 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 1.4 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |