ISMARA results: GUAAACA

Project

GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation

Downloads

Results for GUAAACA

Z-value: 0.92

Motif logo

miRNA associated with seed GUAAACA

Name	miRBASE accession
hsa-miR-30a-5p miRBase	MIMAT0000087
hsa-miR-30b-5p miRBase	MIMAT0000420
hsa-miR-30c-5p miRBase	MIMAT0000244
hsa-miR-30d-5p miRBase	MIMAT0000245
hsa-miR-30e-5p miRBase	MIMAT0000692

Activity profile of GUAAACA motif

Sorted Z-values of GUAAACA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAAACA

View svg image
View png image

Top targets:

Search:

Show entries

Promoter	Score	Transcript	Gene	Gene Info
chr19_+_18097763 Show fit	13.04	ENST00000262811.10	MAST3 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase 3
chr17_-_76240478 Show fit	10.20	ENST00000269391.11	RNF157 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 157
chr8_+_24914942 Show fit	9.72	ENST00000433454.3	NEFM Ensembl NCBI GeneCards UniProt Show fit	neurofilament medium
chr5_+_176365455 Show fit	8.32	ENST00000310389.6	ARL10 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 10
chr3_+_196744 Show fit	7.74	ENST00000256509.7 ENST00000397491.6	CHL1 Ensembl NCBI GeneCards UniProt Show fit	cell adhesion molecule L1 like
chrX_-_136767322 Show fit	7.61	ENST00000370620.5	ARHGEF6 Ensembl NCBI GeneCards UniProt Show fit	Rac/Cdc42 guanine nucleotide exchange factor 6
chr4_+_157220691 Show fit	7.39	ENST00000509417.5 ENST00000645636.1 ENST00000296526.12 ENST00000264426.14	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr18_+_56651335 Show fit	7.37	ENST00000589935.1 ENST00000254442.8 ENST00000357574.7	WDR7 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 7
chr3_-_18425295 Show fit	7.37	ENST00000338745.11 ENST00000450898.1	SATB1 Ensembl NCBI GeneCards UniProt Show fit	SATB homeobox 1
chr18_+_26226417 Show fit	7.20	ENST00000269142.10	TAF4B Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 4b

Showing 1 to 10 of 200 entries

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	17.8	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0	13.0	GO:0051260	protein homooligomerization(GO:0051260)
0.3	12.1	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.6	10.1	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	10.0	GO:0043547	positive regulation of GTPase activity(GO:0043547)
2.4	9.7	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.2	7.7	GO:0035640	exploration behavior(GO:0035640)
0.5	7.6	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.5	7.4	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2	7.4	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)

Showing 1 to 10 of 285 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	69.7	GO:0016021	integral component of membrane(GO:0016021)
0.1	11.0	GO:0008021	synaptic vesicle(GO:0008021)
0.4	10.7	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.4	10.6	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.7	9.8	GO:0097418	neurofibrillary tangle(GO:0097418)
0.2	8.4	GO:1902711	GABA-A receptor complex(GO:1902711)
0.1	8.4	GO:0008023	transcription elongation factor complex(GO:0008023)
0.6	8.2	GO:0030897	HOPS complex(GO:0030897)
0.1	8.2	GO:0042734	presynaptic membrane(GO:0042734)
0.2	8.1	GO:0048786	presynaptic active zone(GO:0048786)

Showing 1 to 10 of 128 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	23.6	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.3	10.7	GO:0017091	AU-rich element binding(GO:0017091)
0.6	10.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.2	9.7	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.1	9.4	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4	8.4	GO:0050811	GABA receptor binding(GO:0050811)
0.0	8.2	GO:0008017	microtubule binding(GO:0008017)
1.3	8.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
1.1	7.7	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.9	7.4	GO:0004971	AMPA glutamate receptor activity(GO:0004971)

Showing 1 to 10 of 194 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	10.7	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	10.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.4	10.5	PID S1P S1P4 PATHWAY	S1P4 pathway
0.2	9.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	8.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	6.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	5.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.2	4.9	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	4.9	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	4.9	PID CASPASE PATHWAY	Caspase cascade in apoptosis

Showing 1 to 10 of 50 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	12.9	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.4	12.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	10.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.2	8.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.3	7.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	7.1	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	6.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.2	6.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	6.1	REACTOME GPCR DOWNSTREAM SIGNALING	Genes involved in GPCR downstream signaling
0.3	5.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex

Showing 1 to 10 of 80 entries

Results for GUAAACA

Z-value: 0.92

Motif logo

miRNA associated with seed GUAAACA

Activity profile of GUAAACA motif

Sorted Z-values of GUAAACA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAAACA

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: