GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
HMBOX1 Links Ensembl NCBI GeneCards UniProt	ENSG00000147421.18	HMBOX1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HMBOX1	hg38_v1_chr8_+_28890365_28890421	-0.34	3.4e-07	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr1_-_152036984 Show fit	29.27	ENST00000271638.3	S100A11 Links Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A11
chr6_+_27147094 Show fit	27.68	ENST00000377459.3	H2AC12 Links Ensembl NCBI GeneCards UniProt Show fit	H2A clustered histone 12
chr3_+_33114033 Show fit	20.26	ENST00000449224.1	CRTAP Links Ensembl NCBI GeneCards UniProt Show fit	cartilage associated protein
chrX_-_20218941 Show fit	16.18	ENST00000457145.6	RPS6KA3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr14_+_55611977 Show fit	15.96	ENST00000395309.7 ENST00000413890.6	KTN1 Links Ensembl NCBI GeneCards UniProt Show fit	kinectin 1
chr9_+_73151833 Show fit	15.87	ENST00000456643.5 ENST00000257497.11 ENST00000415424.5	ANXA1 Links Ensembl NCBI GeneCards UniProt Show fit	annexin A1
chr3_-_149377637 Show fit	14.51	ENST00000305366.8	TM4SF1 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 1
chr1_+_40988513 Show fit	14.12	ENST00000649215.1	CTPS1 Links Ensembl NCBI GeneCards UniProt Show fit	CTP synthase 1
chr14_+_34993240 Show fit	13.31	ENST00000677647.1	SRP54 Links Ensembl NCBI GeneCards UniProt Show fit	signal recognition particle 54
chr6_-_8102481 Show fit	13.08	ENST00000502429.5 ENST00000429723.6 ENST00000379715.10 ENST00000507463.1	EEF1E1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 epsilon 1
chr19_+_16067526 Show fit	12.80	ENST00000646974.2	TPM4 Links Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 4
chrX_-_10833643 Show fit	12.44	ENST00000380785.5 ENST00000380787.5	MID1 Links Ensembl NCBI GeneCards UniProt Show fit	midline 1
chr2_-_99336306 Show fit	11.82	ENST00000264255.8 ENST00000409434.5 ENST00000434323.5	TXNDC9 Links Ensembl NCBI GeneCards UniProt Show fit	thioredoxin domain containing 9
chr14_-_55191534 Show fit	11.75	ENST00000395425.6 ENST00000247191.7	DLGAP5 Links Ensembl NCBI GeneCards UniProt Show fit	DLG associated protein 5
chr18_-_36798482 Show fit	11.68	ENST00000590258.2	TPGS2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr1_-_31919093 Show fit	11.54	ENST00000602683.5 ENST00000470404.5	PTP4A2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A2
chr5_+_96743578 Show fit	11.44	ENST00000325674.11	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr1_-_224434750 Show fit	11.17	ENST00000414423.9 ENST00000678917.1 ENST00000678555.1 ENST00000678307.1	WDR26 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 26
chr6_+_138404206 Show fit	10.44	ENST00000607197.6 ENST00000367697.7	HEBP2 Links Ensembl NCBI GeneCards UniProt Show fit	heme binding protein 2
chr8_+_11809135 Show fit	10.40	ENST00000528643.5 ENST00000525777.5	FDFT1 Links Ensembl NCBI GeneCards UniProt Show fit	farnesyl-diphosphate farnesyltransferase 1
chrX_-_10620419 Show fit	10.35	ENST00000380782.6	MID1 Links Ensembl NCBI GeneCards UniProt Show fit	midline 1
chr1_-_150697128 Show fit	10.15	ENST00000427665.1 ENST00000271732.8	GOLPH3L Links Ensembl NCBI GeneCards UniProt Show fit	golgi phosphoprotein 3 like
chr15_+_79311084 Show fit	9.62	ENST00000299705.10	TMED3 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane p24 trafficking protein 3
chr1_+_236394268 Show fit	9.50	ENST00000334232.9	EDARADD Links Ensembl NCBI GeneCards UniProt Show fit	EDAR associated death domain
chr9_+_99222258 Show fit	9.36	ENST00000223641.5	SEC61B Links Ensembl NCBI GeneCards UniProt Show fit	SEC61 translocon subunit beta
chr8_+_30387064 Show fit	9.34	ENST00000523115.5 ENST00000519647.5	RBPMS Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding protein, mRNA processing factor
chr5_-_134632769 Show fit	9.23	ENST00000505758.5 ENST00000439578.5 ENST00000502286.1 ENST00000402673.7	SAR1B Links Ensembl NCBI GeneCards UniProt Show fit	secretion associated Ras related GTPase 1B
chr17_-_41982321 Show fit	9.09	ENST00000587727.6	DNAJC7 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C7
chr4_-_102868869 Show fit	9.07	ENST00000338145.7 ENST00000357194.10	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chrX_-_10620534 Show fit	8.70	ENST00000317552.9	MID1 Links Ensembl NCBI GeneCards UniProt Show fit	midline 1
chr11_-_47426419 Show fit	8.54	ENST00000298852.8 ENST00000530912.5 ENST00000619920.4	PSMC3 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, ATPase 3
chr7_+_135557904 Show fit	8.48	ENST00000285968.11	NUP205 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 205
chr6_-_27146841 Show fit	8.22	ENST00000356950.2	H2BC12 Links Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 12
chr17_-_3668557 Show fit	8.10	ENST00000225525.4	TAX1BP3 Links Ensembl NCBI GeneCards UniProt Show fit	Tax1 binding protein 3
chrX_+_71283186 Show fit	7.91	ENST00000535149.5	NONO Links Ensembl NCBI GeneCards UniProt Show fit	non-POU domain containing octamer binding
chr1_+_207770322 Show fit	7.54	ENST00000462968.2	CD46 Links Ensembl NCBI GeneCards UniProt Show fit	CD46 molecule
chrX_+_110003095 Show fit	7.29	ENST00000372073.5 ENST00000372068.7 ENST00000288381.4	TMEM164 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 164
chr17_-_3668640 Show fit	7.25	ENST00000611779.4	TAX1BP3 Links Ensembl NCBI GeneCards UniProt Show fit	Tax1 binding protein 3
chr7_+_134891566 Show fit	7.04	ENST00000424922.5 ENST00000495522.1	CALD1 Links Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr10_+_74176537 Show fit	6.90	ENST00000672394.1	ADK Links Ensembl NCBI GeneCards UniProt Show fit	adenosine kinase
chr20_-_44504850 Show fit	6.77	ENST00000411544.5	SERINC3 Links Ensembl NCBI GeneCards UniProt Show fit	serine incorporator 3
chr4_-_47463649 Show fit	6.74	ENST00000381571.6	COMMD8 Links Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 8
chr6_+_30617825 Show fit	6.48	ENST00000259873.5	MRPS18B Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S18B
chr7_+_99408958 Show fit	6.45	ENST00000222969.10	BUD31 Links Ensembl NCBI GeneCards UniProt Show fit	BUD31 homolog
chr12_+_64497968 Show fit	6.21	ENST00000676593.1 ENST00000677093.1	TBK1 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000288665.1 Links Ensembl NCBI GeneCards UniProt Show fit	TANK binding kinase 1 novel transcript
chr7_+_134891400 Show fit	5.94	ENST00000393118.6	CALD1 Links Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr7_+_101817601 Show fit	5.91	ENST00000292535.12 ENST00000546411.7 ENST00000549414.6 ENST00000550008.6 ENST00000556210.1	CUX1 Links Ensembl NCBI GeneCards UniProt Show fit	cut like homeobox 1
chr5_-_69369988 Show fit	5.86	ENST00000380818.7 ENST00000328663.8	AK6 Links Ensembl NCBI GeneCards UniProt Show fit TAF9 Links Ensembl NCBI GeneCards UniProt Show fit	adenylate kinase 6 TATA-box binding protein associated factor 9
chr20_-_50153637 Show fit	5.84	ENST00000341698.2 ENST00000371652.9 ENST00000371650.9	PEDS1-UBE2V1 Links Ensembl NCBI GeneCards UniProt Show fit PEDS1 Links Ensembl NCBI GeneCards UniProt Show fit	PEDS1-UBE2V1 readthrough plasmanylethanolamine desaturase 1
chr10_+_74176741 Show fit	5.82	ENST00000673027.1 ENST00000372734.5 ENST00000541550.6	ADK Links Ensembl NCBI GeneCards UniProt Show fit	adenosine kinase
chr10_+_123154364 Show fit	5.77	ENST00000368859.6 ENST00000368865.9	BUB3 Links Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr5_-_69369257 Show fit	5.59	ENST00000509462.5	TAF9 Links Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 9
chr3_+_36993798 Show fit	5.58	ENST00000455445.6 ENST00000539477.6 ENST00000435176.5 ENST00000429117.5 ENST00000441265.6	MLH1 Links Ensembl NCBI GeneCards UniProt Show fit	mutL homolog 1
chr17_+_3668803 Show fit	5.37	ENST00000248378.6 ENST00000397133.2	EMC6 Links Ensembl NCBI GeneCards UniProt Show fit	ER membrane protein complex subunit 6
chr7_+_95485898 Show fit	5.34	ENST00000428113.5	ASB4 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 4
chr7_+_128739292 Show fit	5.25	ENST00000535011.6 ENST00000542996.6 ENST00000249364.9 ENST00000449187.6	CALU Links Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr1_+_117060309 Show fit	4.94	ENST00000369466.9	TTF2 Links Ensembl NCBI GeneCards UniProt Show fit	transcription termination factor 2
chr11_+_10751203 Show fit	4.72	ENST00000361367.7	CTR9 Links Ensembl NCBI GeneCards UniProt Show fit	CTR9 homolog, Paf1/RNA polymerase II complex component
chr2_+_86907953 Show fit	4.38	ENST00000409776.6	RGPD1 Links Ensembl NCBI GeneCards UniProt Show fit	RANBP2 like and GRIP domain containing 1
chr10_+_35195843 Show fit	4.22	ENST00000488741.5 ENST00000474931.5 ENST00000468236.5 ENST00000344351.5 ENST00000490511.1	CREM Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr12_-_32755876 Show fit	4.03	ENST00000324868.13	YARS2 Links Ensembl NCBI GeneCards UniProt Show fit	tyrosyl-tRNA synthetase 2
chr1_-_26890237 Show fit	3.81	ENST00000431781.2 ENST00000374135.9	GPN2 Links Ensembl NCBI GeneCards UniProt Show fit	GPN-loop GTPase 2
chr5_-_78549151 Show fit	3.70	ENST00000515007.6	LHFPL2 Links Ensembl NCBI GeneCards UniProt Show fit	LHFPL tetraspan subfamily member 2
chr15_-_40038895 Show fit	3.69	ENST00000558720.5	SRP14 Links Ensembl NCBI GeneCards UniProt Show fit	signal recognition particle 14
chr10_-_32935511 Show fit	3.55	ENST00000423113.5	ITGB1 Links Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 1
chr12_+_56128217 Show fit	3.49	ENST00000267113.4 ENST00000394048.10	ESYT1 Links Ensembl NCBI GeneCards UniProt Show fit	extended synaptotagmin 1
chr11_+_57763820 Show fit	3.44	ENST00000674106.1	CTNND1 Links Ensembl NCBI GeneCards UniProt Show fit	catenin delta 1
chr7_+_101085464 Show fit	3.38	ENST00000306085.11 ENST00000412507.1	TRIM56 Links Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 56
chr15_+_78873723 Show fit	3.38	ENST00000559690.5 ENST00000559158.5	MORF4L1 Links Ensembl NCBI GeneCards UniProt Show fit	mortality factor 4 like 1
chr16_+_22297375 Show fit	3.37	ENST00000615879.4 ENST00000299853.10 ENST00000564209.5 ENST00000565358.5 ENST00000418581.6 ENST00000564883.5 ENST00000359210.8 ENST00000563024.5	POLR3E Links Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase III subunit E
chrX_+_71283577 Show fit	3.37	ENST00000420903.6 ENST00000373856.8 ENST00000678437.1 ENST00000678830.1 ENST00000677879.1 ENST00000373841.5 ENST00000276079.13 ENST00000676797.1 ENST00000678660.1 ENST00000678231.1 ENST00000677612.1 ENST00000413858.5 ENST00000450092.6	NONO Links Ensembl NCBI GeneCards UniProt Show fit	non-POU domain containing octamer binding
chr11_-_58578096 Show fit	3.37	ENST00000528954.5 ENST00000528489.1	LPXN Links Ensembl NCBI GeneCards UniProt Show fit	leupaxin
chr7_+_107580454 Show fit	3.36	ENST00000379117.6 ENST00000473124.1	BCAP29 Links Ensembl NCBI GeneCards UniProt Show fit	B cell receptor associated protein 29
chr1_+_174875505 Show fit	3.36	ENST00000486220.5	RABGAP1L Links Ensembl NCBI GeneCards UniProt Show fit	RAB GTPase activating protein 1 like
chr2_-_27409523 Show fit	3.36	ENST00000344034.5	PPM1G Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1G
chr3_-_93973933 Show fit	3.35	ENST00000650591.1	PROS1 Links Ensembl NCBI GeneCards UniProt Show fit	protein S
chr9_+_125748175 Show fit	3.33	ENST00000491787.7 ENST00000447726.6	PBX3 Links Ensembl NCBI GeneCards UniProt Show fit	PBX homeobox 3
chr14_+_67240713 Show fit	3.31	ENST00000677382.1	MPP5 Links Ensembl NCBI GeneCards UniProt Show fit	membrane palmitoylated protein 5
chr7_+_128455849 Show fit	3.27	ENST00000435296.2 ENST00000257696.5	HILPDA Links Ensembl NCBI GeneCards UniProt Show fit	hypoxia inducible lipid droplet associated
chr16_-_67247460 Show fit	3.26	ENST00000258201.9	FHOD1 Links Ensembl NCBI GeneCards UniProt Show fit	formin homology 2 domain containing 1
chr2_+_27771700 Show fit	3.19	ENST00000379666.7 ENST00000296102.8	MRPL33 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L33
chr2_+_68157877 Show fit	3.18	ENST00000263657.7	PNO1 Links Ensembl NCBI GeneCards UniProt Show fit	partner of NOB1 homolog
chr14_-_75069478 Show fit	3.08	ENST00000555463.1	ACYP1 Links Ensembl NCBI GeneCards UniProt Show fit	acylphosphatase 1
chr3_+_33114007 Show fit	3.03	ENST00000320954.11	CRTAP Links Ensembl NCBI GeneCards UniProt Show fit	cartilage associated protein
chr11_-_57427474 Show fit	2.97	ENST00000533235.5 ENST00000526621.5 ENST00000352187.5	SLC43A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 43 member 3
chr12_+_51239278 Show fit	2.88	ENST00000551313.1	DAZAP2 Links Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 2
chr2_+_161231078 Show fit	2.86	ENST00000439442.1	TANK Links Ensembl NCBI GeneCards UniProt Show fit	TRAF family member associated NFKB activator
chr20_-_2664186 Show fit	2.84	ENST00000474315.5 ENST00000380843.9 ENST00000380851.9 ENST00000613370.1	IDH3B Links Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
chr14_+_89955895 Show fit	2.79	ENST00000393452.7 ENST00000554180.5 ENST00000335725.9 ENST00000393454.6 ENST00000553617.5 ENST00000556867.1 ENST00000553527.1	TDP1 Links Ensembl NCBI GeneCards UniProt Show fit	tyrosyl-DNA phosphodiesterase 1
chr10_+_87659839 Show fit	2.77	ENST00000456849.2	PAPSS2 Links Ensembl NCBI GeneCards UniProt Show fit	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_+_108719473 Show fit	2.68	ENST00000283195.11	RANBP2 Links Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 2
chr5_-_138331770 Show fit	2.67	ENST00000415130.6 ENST00000323760.11 ENST00000503022.5	CDC25C Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 25C
chr1_-_109740304 Show fit	2.64	ENST00000540225.2	GSTM3 Links Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase mu 3
chrX_+_103628959 Show fit	2.55	ENST00000372625.8 ENST00000372624.3	TCEAL1 Links Ensembl NCBI GeneCards UniProt Show fit	transcription elongation factor A like 1
chr8_-_94436926 Show fit	2.45	ENST00000481490.3	FSBP Links Ensembl NCBI GeneCards UniProt Show fit	fibrinogen silencer binding protein
chr11_-_31806886 Show fit	2.42	ENST00000640963.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chrX_-_75156272 Show fit	2.38	ENST00000620875.5 ENST00000669573.1 ENST00000339447.8 ENST00000645829.3 ENST00000529949.5 ENST00000373394.8 ENST00000253577.9 ENST00000644766.1 ENST00000534524.5	ABCB7 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily B member 7
chr14_+_64388296 Show fit	2.36	ENST00000554739.5 ENST00000554768.6 ENST00000652179.1 ENST00000652337.1 ENST00000557370.3	MTHFD1 Links Ensembl NCBI GeneCards UniProt Show fit	methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
chr6_-_73520170 Show fit	2.36	ENST00000678508.1	EEF1A1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 alpha 1
chr17_-_10549652 Show fit	2.29	ENST00000245503.10	MYH2 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr1_-_92792396 Show fit	2.22	ENST00000370331.5 ENST00000540033.2	EVI5 Links Ensembl NCBI GeneCards UniProt Show fit	ecotropic viral integration site 5
chr4_+_56907876 Show fit	2.19	ENST00000640168.2 ENST00000309042.12	REST Links Ensembl NCBI GeneCards UniProt Show fit	RE1 silencing transcription factor
chr6_+_26199509 Show fit	2.13	ENST00000356530.5	H2BC7 Links Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 7
chr14_-_70416994 Show fit	2.13	ENST00000621525.4 ENST00000256366.6	SYNJ2BP-COX16 Links Ensembl NCBI GeneCards UniProt Show fit SYNJ2BP Links Ensembl NCBI GeneCards UniProt Show fit	SYNJ2BP-COX16 readthrough synaptojanin 2 binding protein
chr17_-_10549612 Show fit	2.12	ENST00000532183.6 ENST00000397183.6 ENST00000420805.1	MYH2 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr14_-_50532590 Show fit	2.10	ENST00000013125.9	MAP4K5 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 5
chr5_+_139293728 Show fit	2.02	ENST00000510056.5 ENST00000511249.5 ENST00000394805.8 ENST00000503811.5 ENST00000618441.5	MATR3 Links Ensembl NCBI GeneCards UniProt Show fit	matrin 3
chr8_+_55102012 Show fit	2.02	ENST00000327381.7	XKR4 Links Ensembl NCBI GeneCards UniProt Show fit	XK related 4
chr14_+_104865256 Show fit	2.00	ENST00000414716.8 ENST00000556508.5 ENST00000453495.2	CEP170B Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 170B
chr1_-_167518583 Show fit	2.00	ENST00000392122.3	CD247 Links Ensembl NCBI GeneCards UniProt Show fit	CD247 molecule
chr22_-_36776067 Show fit	1.92	ENST00000417951.6 ENST00000433985.7 ENST00000430701.5	IFT27 Links Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 27
chr1_-_110391041 Show fit	1.90	ENST00000369781.8 ENST00000437429.6 ENST00000541986.5	SLC16A4 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 4
chr4_-_109801978 Show fit	1.86	ENST00000510800.1 ENST00000512148.5 ENST00000394634.7 ENST00000394635.8 ENST00000645635.1	CFI Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000285330.1 Links Ensembl NCBI GeneCards UniProt Show fit	complement factor I novel protein
chr17_-_5486157 Show fit	1.84	ENST00000572834.5 ENST00000158771.9 ENST00000570848.5 ENST00000571971.1	DERL2 Links Ensembl NCBI GeneCards UniProt Show fit	derlin 2
chr10_-_5003850 Show fit	1.77	ENST00000421196.7 ENST00000455190.2 ENST00000380753.8	AKR1C2 Links Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1 member C2
chr12_+_53098846 Show fit	1.76	ENST00000650247.1 ENST00000549628.1	IGFBP6 Links Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 6
chr5_-_16916400 Show fit	1.76	ENST00000513882.5	MYO10 Links Ensembl NCBI GeneCards UniProt Show fit	myosin X
chr14_-_23154369 Show fit	1.69	ENST00000453702.5	SLC7A8 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 8
chr1_+_23959797 Show fit	1.67	ENST00000374468.1 ENST00000334351.8	PNRC2 Links Ensembl NCBI GeneCards UniProt Show fit	proline rich nuclear receptor coactivator 2
chr16_-_71809049 Show fit	1.66	ENST00000569748.5 ENST00000570017.1 ENST00000393512.7	AP1G1 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit gamma 1
chr1_+_116111395 Show fit	1.63	ENST00000684484.1 ENST00000369500.4	MAB21L3 Links Ensembl NCBI GeneCards UniProt Show fit	mab-21 like 3
chr11_+_65576023 Show fit	1.59	ENST00000533237.5 ENST00000309295.9 ENST00000634639.1	EHBP1L1 Links Ensembl NCBI GeneCards UniProt Show fit	EH domain binding protein 1 like 1
chr4_-_139084289 Show fit	1.58	ENST00000510408.5 ENST00000379549.7 ENST00000358635.7	ELF2 Links Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 2
chr22_-_19431692 Show fit	1.51	ENST00000340170.8 ENST00000263208.5	HIRA Links Ensembl NCBI GeneCards UniProt Show fit	histone cell cycle regulator
chr10_-_52771700 Show fit	1.47	ENST00000373968.3	MBL2 Links Ensembl NCBI GeneCards UniProt Show fit	mannose binding lectin 2
chr22_-_36776147 Show fit	1.45	ENST00000340630.9	IFT27 Links Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 27
chr4_-_158159657 Show fit	1.40	ENST00000590648.5	GASK1B Links Ensembl NCBI GeneCards UniProt Show fit	golgi associated kinase 1B
chrX_+_71533095 Show fit	1.36	ENST00000373719.8 ENST00000373701.7	OGT Links Ensembl NCBI GeneCards UniProt Show fit	O-linked N-acetylglucosamine (GlcNAc) transferase
chr2_-_55296361 Show fit	1.35	ENST00000647547.1	CCDC88A Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr17_-_58417521 Show fit	1.25	ENST00000584437.5 ENST00000407977.7	RNF43 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 43
chr9_-_120793377 Show fit	1.24	ENST00000684001.1 ENST00000684405.1 ENST00000608872.6	FBXW2 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 2
chr9_-_120793343 Show fit	1.23	ENST00000684047.1	FBXW2 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 2
chr1_-_167518521 Show fit	1.23	ENST00000362089.10	CD247 Links Ensembl NCBI GeneCards UniProt Show fit	CD247 molecule
chr3_-_121749704 Show fit	1.22	ENST00000393667.7 ENST00000340645.9 ENST00000614479.4	GOLGB1 Links Ensembl NCBI GeneCards UniProt Show fit	golgin B1
chr17_-_10549694 Show fit	1.21	ENST00000622564.4	MYH2 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr1_-_25859352 Show fit	1.20	ENST00000374298.4 ENST00000538789.5	AUNIP Links Ensembl NCBI GeneCards UniProt Show fit	aurora kinase A and ninein interacting protein
chr11_+_117327829 Show fit	1.18	ENST00000533153.5 ENST00000278935.8 ENST00000525416.5	CEP164 Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 164
chr17_-_58417547 Show fit	1.10	ENST00000577716.5	RNF43 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 43
chr2_-_213151590 Show fit	1.03	ENST00000374319.8 ENST00000457361.5 ENST00000451136.6 ENST00000434687.6	IKZF2 Links Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 2
chr14_-_50532518 Show fit	1.03	ENST00000682126.1	MAP4K5 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 5
chr14_+_22281097 Show fit	1.02	ENST00000390465.2	TRAV38-2DV8 Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 38-2/delta variable 8
chr16_-_71808803 Show fit	1.01	ENST00000563104.5 ENST00000569975.5 ENST00000565412.5 ENST00000567583.1 ENST00000299980.9	AP1G1 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit gamma 1
chr2_+_46542474 Show fit	0.93	ENST00000238738.9	RHOQ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member Q
chr4_+_73481737 Show fit	0.92	ENST00000226355.5	AFM Links Ensembl NCBI GeneCards UniProt Show fit	afamin
chr1_+_206470463 Show fit	0.87	ENST00000581977.7 ENST00000578328.6 ENST00000584998.5 ENST00000579827.6	IKBKE Links Ensembl NCBI GeneCards UniProt Show fit	inhibitor of nuclear factor kappa B kinase subunit epsilon
chr17_-_1492660 Show fit	0.84	ENST00000648651.1	MYO1C Links Ensembl NCBI GeneCards UniProt Show fit	myosin IC
chr16_-_30585497 Show fit	0.79	ENST00000567773.1 ENST00000395216.3 ENST00000470110.2	ZNF785 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 785
chr1_-_217076889 Show fit	0.74	ENST00000493748.5 ENST00000463665.5	ESRRG Links Ensembl NCBI GeneCards UniProt Show fit	estrogen related receptor gamma
chr11_-_31807617 Show fit	0.74	ENST00000639920.1 ENST00000640460.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr11_-_62805429 Show fit	0.69	ENST00000294172.7 ENST00000531131.1 ENST00000530875.5 ENST00000531709.6	NXF1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear RNA export factor 1
chr18_-_66604076 Show fit	0.63	ENST00000540086.5 ENST00000580157.2 ENST00000262150.7	CDH19 Links Ensembl NCBI GeneCards UniProt Show fit	cadherin 19
chr5_+_93583212 Show fit	0.56	ENST00000327111.8	NR2F1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group F member 1
chrX_-_21758097 Show fit	0.55	ENST00000379494.4	SMPX Links Ensembl NCBI GeneCards UniProt Show fit	small muscle protein X-linked
chr12_+_67648737 Show fit	0.53	ENST00000344096.4 ENST00000393555.3	DYRK2 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity tyrosine phosphorylation regulated kinase 2
chr1_-_197067234 Show fit	0.48	ENST00000367412.2	F13B Links Ensembl NCBI GeneCards UniProt Show fit	coagulation factor XIII B chain
chr4_+_73436198 Show fit	0.47	ENST00000395792.7	AFP Links Ensembl NCBI GeneCards UniProt Show fit	alpha fetoprotein
chr7_-_123199960 Show fit	0.44	ENST00000194130.7	SLC13A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 13 member 1
chr12_-_10810168 Show fit	0.41	ENST00000240691.4	TAS2R9 Links Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 9
chr8_+_67064316 Show fit	0.36	ENST00000675306.2 ENST00000678017.1 ENST00000262210.11 ENST00000675869.1 ENST00000677009.1 ENST00000676847.1 ENST00000676471.1 ENST00000678542.1 ENST00000677619.1 ENST00000676605.1 ENST00000678553.1 ENST00000674993.1 ENST00000678318.1 ENST00000676573.1 ENST00000676317.1 ENST00000677592.1 ENST00000679226.1 ENST00000675955.1 ENST00000676882.1 ENST00000678616.1 ENST00000678645.1 ENST00000678747.1	CSPP1 Links Ensembl NCBI GeneCards UniProt Show fit	centrosome and spindle pole associated protein 1
chr17_-_37643422 Show fit	0.35	ENST00000617633.5	DDX52 Links Ensembl NCBI GeneCards UniProt Show fit	DExD-box helicase 52
chr12_-_68225806 Show fit	0.35	ENST00000229134.5	IL26 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 26
chr3_+_52410635 Show fit	0.32	ENST00000327906.8	PHF7 Links Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 7
chr12_-_10435940 Show fit	0.27	ENST00000381901.5 ENST00000381902.7 ENST00000539033.1	KLRC2 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000255641.1 Links Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor C2 novel protein
chrX_+_136648138 Show fit	0.27	ENST00000370629.7	CD40LG Links Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr2_+_102001966 Show fit	0.26	ENST00000457817.5	IL1R2 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor type 2
chr18_-_21703688 Show fit	0.26	ENST00000584464.1 ENST00000578270.5	ABHD3 Links Ensembl NCBI GeneCards UniProt Show fit	abhydrolase domain containing 3, phospholipase
chr20_+_44582549 Show fit	0.25	ENST00000372886.6	PKIG Links Ensembl NCBI GeneCards UniProt Show fit	cAMP-dependent protein kinase inhibitor gamma
chr1_+_175067831 Show fit	0.23	ENST00000239462.9	TNN Links Ensembl NCBI GeneCards UniProt Show fit	tenascin N
chr5_+_132369691 Show fit	0.22	ENST00000245407.8	SLC22A5 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 5
chr13_+_76992412 Show fit	0.16	ENST00000636705.1	CLN5 Links Ensembl NCBI GeneCards UniProt Show fit	CLN5 intracellular trafficking protein
chr4_+_9170409 Show fit	0.09	ENST00000512047.2	FAM90A26 Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 90 member A26
chr12_+_28190420 Show fit	0.09	ENST00000539107.5 ENST00000545336.5	CCDC91 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 91
chr8_-_123737378 Show fit	0.08	ENST00000419625.6 ENST00000262219.10	ANXA13 Links Ensembl NCBI GeneCards UniProt Show fit	annexin A13
chr12_+_4649097 Show fit	0.05	ENST00000648836.1 ENST00000266544.10	ENSG00000255639.3 Links Ensembl NCBI GeneCards UniProt Show fit NDUFA9 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein NADH:ubiquinone oxidoreductase subunit A9
chr10_+_122560751 Show fit	0.04	ENST00000338354.10 ENST00000664692.1 ENST00000653442.1 ENST00000664974.1	DMBT1 Links Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr12_-_32896757 Show fit	0.03	ENST00000070846.11 ENST00000340811.9	PKP2 Links Ensembl NCBI GeneCards UniProt Show fit	plakophilin 2

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.8	23.3	GO:1901874	negative regulation of post-translational protein modification(GO:1901874)
5.3	15.9	GO:0036292	DNA rewinding(GO:0036292)
3.5	14.1	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
3.3	13.3	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
3.2	12.7	GO:0009216	adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
3.1	9.4	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
3.0	11.8	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
2.2	31.5	GO:0035372	protein localization to microtubule(GO:0035372)
2.1	6.2	GO:0044565	dendritic cell proliferation(GO:0044565)
2.0	11.8	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
1.7	10.4	GO:0008204	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
1.6	4.7	GO:0034729	histone H3-K79 methylation(GO:0034729) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
1.4	5.6	GO:0043060	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
1.3	3.8	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
1.1	11.3	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.1	3.3	GO:0035425	autocrine signaling(GO:0035425)
1.0	10.4	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.9	13.1	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.9	2.8	GO:0000103	sulfate assimilation(GO:0000103)
0.9	10.2	GO:0048194	Golgi vesicle budding(GO:0048194)
0.9	2.7	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.9	2.6	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.8	6.8	GO:0009597	detection of virus(GO:0009597)
0.8	3.3	GO:0035750	protein localization to myelin sheath abaxonal region(GO:0035750)
0.8	11.5	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.8	2.4	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.7	6.7	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
0.7	2.2	GO:2000740	amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.7	3.4	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.7	3.3	GO:0007386	compartment pattern specification(GO:0007386)
0.6	15.4	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.6	2.4	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.6	4.0	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.5	9.3	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.5	9.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.5	3.6	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
0.5	11.4	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.5	16.2	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.5	2.9	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4	2.7	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.4	8.5	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.4	3.4	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.4	2.8	GO:0006102	isocitrate metabolic process(GO:0006102)
0.4	5.6	GO:0001778	plasma membrane repair(GO:0001778)
0.4	8.5	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.3	1.8	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3	10.3	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.3	5.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.3	24.3	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.3	2.4	GO:0015886	heme transport(GO:0015886)
0.2	1.8	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2	1.3	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.2	3.4	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.2	4.0	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.2	3.3	GO:0007097	nuclear migration(GO:0007097)
0.2	9.1	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.2	1.4	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.2	3.2	GO:0003322	pancreatic A cell development(GO:0003322)
0.2	1.7	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2	3.3	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2	2.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.2	5.8	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.1	3.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	3.4	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.1	9.7	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.1	9.5	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	3.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.2	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.2	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.1	9.2	GO:0048207	vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	0.8	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	14.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	1.5	GO:0051873	complement activation, lectin pathway(GO:0001867) killing by host of symbiont cells(GO:0051873)
0.1	0.5	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1	3.2	GO:0070207	protein homotrimerization(GO:0070207)
0.1	3.4	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.1	3.4	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.1	1.5	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.1	1.6	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.1	0.6	GO:0000012	single strand break repair(GO:0000012)
0.1	5.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1	16.0	GO:0007018	microtubule-based movement(GO:0007018)
0.1	0.3	GO:0032690	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1	0.9	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	5.6	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.1	3.6	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	1.8	GO:0030705	cytoskeleton-dependent intracellular transport(GO:0030705)
0.1	0.4	GO:1902358	sulfate transmembrane transport(GO:1902358)
0.1	3.4	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.1	1.8	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.9	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	2.4	GO:0006414	translational elongation(GO:0006414)
0.0	0.5	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	1.4	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	7.0	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	3.7	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	11.8	GO:0006936	muscle contraction(GO:0006936)
0.0	3.5	GO:0006364	rRNA processing(GO:0006364)
0.0	0.3	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.9	GO:0051180	vitamin transport(GO:0051180)
0.0	0.4	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	1.2	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	1.9	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.1	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.4	GO:0032467	positive regulation of cytokinesis(GO:0032467)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	8.5	GO:0044611	nuclear pore inner ring(GO:0044611)
2.6	15.9	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
2.5	7.5	GO:0002079	inner acrosomal membrane(GO:0002079)
2.2	13.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.9	5.8	GO:0033597	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
1.9	17.0	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
1.8	9.2	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
1.8	5.4	GO:1903349	omegasome membrane(GO:1903349)
1.4	11.5	GO:0070761	pre-snoRNP complex(GO:0070761)
1.4	5.6	GO:0005715	late recombination nodule(GO:0005715)
1.3	11.3	GO:0042382	paraspeckles(GO:0042382)
1.2	3.6	GO:0034677	integrin alpha7-beta1 complex(GO:0034677)
1.1	5.6	GO:0005826	actomyosin contractile ring(GO:0005826)
0.9	12.8	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.9	2.7	GO:1990723	cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.9	13.0	GO:0030478	actin cap(GO:0030478)
0.9	8.5	GO:0031595	nuclear proteasome complex(GO:0031595)
0.6	11.8	GO:0031616	spindle pole centrosome(GO:0031616)
0.5	5.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.5	4.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4	5.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.4	4.7	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.4	31.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.4	1.8	GO:0048500	signal recognition particle(GO:0048500)
0.4	9.3	GO:0005685	U1 snRNP(GO:0005685)
0.3	3.3	GO:0032059	bleb(GO:0032059)
0.3	3.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.3	3.4	GO:0005915	zonula adherens(GO:0005915)
0.3	3.3	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.3	2.5	GO:0035686	sperm fibrous sheath(GO:0035686)
0.2	6.5	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2	2.4	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2	19.4	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.2	28.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.2	3.5	GO:0044232	organelle membrane contact site(GO:0044232)
0.2	3.4	GO:0016580	Sin3 complex(GO:0016580)
0.2	0.8	GO:0045160	myosin I complex(GO:0045160)
0.2	2.8	GO:0097225	sperm midpiece(GO:0097225)
0.1	1.8	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	3.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.6	GO:0005927	muscle tendon junction(GO:0005927)
0.1	39.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	1.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.1	3.2	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	1.8	GO:0032433	filopodium tip(GO:0032433)
0.1	14.5	GO:0001650	fibrillar center(GO:0001650)
0.1	4.9	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	9.3	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	3.4	GO:0002102	podosome(GO:0002102)
0.1	11.8	GO:0030496	midbody(GO:0030496)
0.1	2.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	3.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	3.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.7	GO:0000346	transcription export complex(GO:0000346)
0.0	1.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	1.5	GO:0005581	collagen trimer(GO:0005581)
0.0	0.9	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	2.0	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	1.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	1.3	GO:0005814	centriole(GO:0005814)
0.0	3.8	GO:0005819	spindle(GO:0005819)
0.0	1.4	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.0	12.5	GO:0005768	endosome(GO:0005768)
0.0	11.4	GO:0005789	endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	14.1	GO:0003883	CTP synthase activity(GO:0003883)
3.2	12.7	GO:0004001	adenosine kinase activity(GO:0004001)
3.2	15.9	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
2.8	17.0	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
2.0	11.8	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
1.9	9.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
1.7	10.4	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
1.3	9.4	GO:0048408	epidermal growth factor binding(GO:0048408)
1.3	11.5	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
1.2	29.3	GO:0044548	S100 protein binding(GO:0044548)
1.1	11.4	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.9	8.5	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.9	2.8	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.7	2.8	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.7	5.9	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.6	2.4	GO:0004488	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.6	6.8	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.5	3.1	GO:0003998	acylphosphatase activity(GO:0003998)
0.5	2.9	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.5	5.6	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.5	10.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5	1.4	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4	3.6	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4	16.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.4	9.9	GO:0005523	tropomyosin binding(GO:0005523)
0.4	1.8	GO:0018636	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.3	18.6	GO:0019894	kinesin binding(GO:0019894)
0.3	0.9	GO:0032427	GBD domain binding(GO:0032427)
0.3	0.9	GO:0008431	vitamin E binding(GO:0008431)
0.3	2.4	GO:0015232	heme transporter activity(GO:0015232)
0.3	14.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.3	0.9	GO:0008384	IkappaB kinase activity(GO:0008384)
0.3	8.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.3	4.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.3	9.1	GO:0001671	ATPase activator activity(GO:0001671)
0.2	31.1	GO:0051219	phosphoprotein binding(GO:0051219)
0.2	7.5	GO:0001848	complement binding(GO:0001848)
0.2	1.8	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.2	5.6	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.2	6.3	GO:0000146	microfilament motor activity(GO:0000146)
0.2	4.0	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.2	8.1	GO:0050699	WW domain binding(GO:0050699)
0.2	3.4	GO:0001056	RNA polymerase III activity(GO:0001056)
0.2	1.8	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.2	3.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	4.7	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.1	2.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	14.6	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	2.7	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	1.4	GO:0019534	toxin transporter activity(GO:0019534)
0.1	2.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	8.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	2.8	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	0.3	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1	10.9	GO:0008013	beta-catenin binding(GO:0008013)
0.1	5.1	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	1.3	GO:0043422	protein kinase B binding(GO:0043422)
0.1	1.6	GO:0005537	mannose binding(GO:0005537)
0.1	2.4	GO:0005109	frizzled binding(GO:0005109)
0.1	0.2	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	0.6	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	15.1	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.1	0.2	GO:0005174	CD40 receptor binding(GO:0005174)
0.1	3.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.4	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1	0.3	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.1	0.3	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1	4.9	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	3.3	GO:0043621	protein self-association(GO:0043621)
0.0	9.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	1.5	GO:0031491	nucleosome binding(GO:0031491)
0.0	3.2	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.0	4.6	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.4	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	1.9	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.7	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	1.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	3.3	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	2.3	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	4.0	GO:0061630	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	18.8	GO:0032403	protein complex binding(GO:0032403)
0.0	5.6	GO:0005096	GTPase activator activity(GO:0005096)
0.0	3.2	GO:0003924	GTPase activity(GO:0003924)
0.0	0.5	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	11.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.4	15.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.4	16.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2	11.5	PID MYC PATHWAY	C-MYC pathway
0.2	11.8	PID AURORA A PATHWAY	Aurora A signaling
0.2	9.1	PID BARD1 PATHWAY	BARD1 signaling events
0.1	2.7	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	5.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	3.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	17.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	4.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	3.8	PID ATR PATHWAY	ATR signaling pathway
0.1	3.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	27.3	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	2.2	PID AURORA B PATHWAY	Aurora B signaling
0.0	1.8	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.9	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	3.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	1.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	5.6	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	3.2	PID CDC42 PATHWAY	CDC42 signaling events
0.0	4.2	PID P73PATHWAY	p73 transcription factor network
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.5	PID P53 REGULATION PATHWAY	p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	13.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.5	12.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.5	25.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.4	9.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	23.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.4	16.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.3	7.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3	11.2	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.3	7.7	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	2.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.3	9.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3	10.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.3	4.0	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.2	3.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	17.9	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.2	2.7	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2	5.8	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2	5.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	5.6	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.2	3.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.2	2.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.2	3.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	2.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	1.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	2.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	3.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	2.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	17.0	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	0.7	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	3.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	3.4	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.1	1.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	0.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	14.9	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	5.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	2.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	1.8	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	4.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	1.2	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport