GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
HMX1 Links Ensembl NCBI GeneCards UniProt	ENSG00000215612.8	HMX1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HMX1	hg38_v1_chr4_-_8871817_8871857	-0.70	4.0e-33	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr3_-_49029378 Show fit	39.23	ENST00000442157.2 ENST00000326739.9 ENST00000677010.1 ENST00000678724.1 ENST00000429182.6	IMPDH2 Links Ensembl NCBI GeneCards UniProt Show fit	inosine monophosphate dehydrogenase 2
chr22_+_20116099 Show fit	25.98	ENST00000430524.6	RANBP1 Links Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 1
chrX_+_49171889 Show fit	21.37	ENST00000376327.6	PLP2 Links Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 2
chr12_-_6967962 Show fit	20.17	ENST00000545555.2	PHB2 Links Ensembl NCBI GeneCards UniProt Show fit	prohibitin 2
chr1_-_25906457 Show fit	18.62	ENST00000426559.6	STMN1 Links Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr1_-_153977260 Show fit	17.65	ENST00000428469.1	JTB Links Ensembl NCBI GeneCards UniProt Show fit	jumping translocation breakpoint
chrX_-_154019800 Show fit	16.89	ENST00000444230.5 ENST00000393687.6 ENST00000429936.6 ENST00000369974.6 ENST00000369980.8	IRAK1 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor associated kinase 1
chr1_-_183635659 Show fit	16.61	ENST00000367534.5 ENST00000294742.6	ARPC5 Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2/3 complex subunit 5
chr13_+_75549734 Show fit	16.59	ENST00000563635.5 ENST00000377595.8	ENSG00000261553.5 Links Ensembl NCBI GeneCards UniProt Show fit UCHL3 Links Ensembl NCBI GeneCards UniProt Show fit	novel transcript ubiquitin C-terminal hydrolase L3
chr13_+_75549477 Show fit	16.08	ENST00000618773.4	UCHL3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin C-terminal hydrolase L3
chr1_-_183635776 Show fit	16.06	ENST00000359856.11	ARPC5 Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2/3 complex subunit 5
chr22_-_38700655 Show fit	15.34	ENST00000216039.9	JOSD1 Links Ensembl NCBI GeneCards UniProt Show fit	Josephin domain containing 1
chr18_-_36798482 Show fit	15.04	ENST00000590258.2	TPGS2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr1_+_155308748 Show fit	14.93	ENST00000611010.4 ENST00000447866.5 ENST00000368356.9 ENST00000467076.5 ENST00000491013.5 ENST00000356657.10	FDPS Links Ensembl NCBI GeneCards UniProt Show fit	farnesyl diphosphate synthase
chr13_+_37000774 Show fit	14.79	ENST00000389704.4	EXOSC8 Links Ensembl NCBI GeneCards UniProt Show fit	exosome component 8
chr19_+_41262480 Show fit	14.79	ENST00000352456.7 ENST00000595018.5 ENST00000597725.5	HNRNPUL1 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein U like 1
chr3_+_152268920 Show fit	14.18	ENST00000495875.6 ENST00000324210.10 ENST00000493459.5	MBNL1 Links Ensembl NCBI GeneCards UniProt Show fit	muscleblind like splicing regulator 1
chr1_+_155308930 Show fit	13.89	ENST00000465559.5 ENST00000612683.1	FDPS Links Ensembl NCBI GeneCards UniProt Show fit	farnesyl diphosphate synthase
chr8_+_38996766 Show fit	13.45	ENST00000676765.1	ADAM9 Links Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 9
chr1_-_53940100 Show fit	12.88	ENST00000371376.1	HSPB11 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chr16_+_85611401 Show fit	12.68	ENST00000405402.6	GSE1 Links Ensembl NCBI GeneCards UniProt Show fit	Gse1 coiled-coil protein
chr8_+_38996899 Show fit	12.59	ENST00000677582.1 ENST00000676643.1 ENST00000676936.1 ENST00000677004.1 ENST00000487273.7 ENST00000481513.5	ADAM9 Links Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 9
chr22_-_38700920 Show fit	12.51	ENST00000456626.1 ENST00000412832.1 ENST00000683374.1	JOSD1 Links Ensembl NCBI GeneCards UniProt Show fit	Josephin domain containing 1
chr11_+_106077638 Show fit	12.33	ENST00000278618.9	AASDHPPT Links Ensembl NCBI GeneCards UniProt Show fit	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr18_+_158513 Show fit	12.16	ENST00000400266.7 ENST00000580410.5 ENST00000261601.8 ENST00000383589.6	USP14 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 14
chr22_-_37244237 Show fit	11.72	ENST00000401529.3 ENST00000249071.11	RAC2 Links Ensembl NCBI GeneCards UniProt Show fit	Rac family small GTPase 2
chr2_-_27323006 Show fit	11.62	ENST00000402310.5 ENST00000405983.5 ENST00000403262.6	MPV17 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial inner membrane protein MPV17
chr14_+_23306958 Show fit	11.36	ENST00000554635.1 ENST00000557008.2	BCL2L2 Links Ensembl NCBI GeneCards UniProt Show fit BCL2L2-PABPN1 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2 like 2 BCL2L2-PABPN1 readthrough
chr15_+_65869974 Show fit	11.32	ENST00000567671.1	RAB11A Links Ensembl NCBI GeneCards UniProt Show fit	RAB11A, member RAS oncogene family
chr3_+_49674344 Show fit	11.23	ENST00000296456.10 ENST00000442186.5 ENST00000438011.5 ENST00000457042.1	APEH Links Ensembl NCBI GeneCards UniProt Show fit	acylaminoacyl-peptide hydrolase
chr6_-_8102046 Show fit	11.15	ENST00000488226.2	EEF1E1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 epsilon 1
chr4_-_1248976 Show fit	10.92	ENST00000514210.5 ENST00000382952.8 ENST00000290921.10	CTBP1 Links Ensembl NCBI GeneCards UniProt Show fit	C-terminal binding protein 1
chr21_-_43107553 Show fit	10.91	ENST00000380276.6 ENST00000291552.9	U2AF1 Links Ensembl NCBI GeneCards UniProt Show fit	U2 small nuclear RNA auxiliary factor 1
chr6_+_163414701 Show fit	10.89	ENST00000361752.8	QKI Links Ensembl NCBI GeneCards UniProt Show fit	QKI, KH domain containing RNA binding
chr4_+_83035159 Show fit	10.48	ENST00000509317.5 ENST00000264389.7 ENST00000503682.5 ENST00000511653.1	COPS4 Links Ensembl NCBI GeneCards UniProt Show fit	COP9 signalosome subunit 4
chr8_-_66613208 Show fit	10.45	ENST00000522677.8	MYBL1 Links Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene like 1
chrX_-_154490614 Show fit	10.38	ENST00000369649.8 ENST00000393586.1 ENST00000651600.1	SLC10A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 10 member 3
chrX_-_154490650 Show fit	10.36	ENST00000393587.4 ENST00000453912.1 ENST00000263512.5	SLC10A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 10 member 3
chrX_+_70290077 Show fit	10.28	ENST00000374403.4	KIF4A Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 4A
chr1_+_154974672 Show fit	10.21	ENST00000308987.6 ENST00000368436.1	CKS1B Links Ensembl NCBI GeneCards UniProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr17_-_7393404 Show fit	9.98	ENST00000575434.4	PLSCR3 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 3
chr2_-_130181542 Show fit	9.95	ENST00000441135.1 ENST00000680679.1 ENST00000680401.1 ENST00000351288.10 ENST00000680298.1 ENST00000431183.6	SMPD4 Links Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase 4
chr14_+_58200106 Show fit	9.75	ENST00000254286.9	ACTR10 Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 10
chr3_-_52278620 Show fit	9.74	ENST00000296490.8	WDR82 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 82
chr7_+_832488 Show fit	9.69	ENST00000405266.5 ENST00000403868.5 ENST00000425407.6	SUN1 Links Ensembl NCBI GeneCards UniProt Show fit	Sad1 and UNC84 domain containing 1
chr1_-_25906411 Show fit	9.52	ENST00000455785.7	STMN1 Links Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chrX_-_20266834 Show fit	9.42	ENST00000379565.9	RPS6KA3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr1_+_154974653 Show fit	9.37	ENST00000368439.5	CKS1B Links Ensembl NCBI GeneCards UniProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr7_+_832470 Show fit	9.31	ENST00000401592.6	SUN1 Links Ensembl NCBI GeneCards UniProt Show fit	Sad1 and UNC84 domain containing 1
chr1_+_39081410 Show fit	9.21	ENST00000602421.5 ENST00000361689.7	MACF1 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule actin crosslinking factor 1
chr22_+_37953666 Show fit	9.18	ENST00000460648.5 ENST00000407936.5 ENST00000488684.5 ENST00000492213.5 ENST00000442738.7 ENST00000606538.5 ENST00000405557.5 ENST00000470701.1	POLR2F Links Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II, I and III subunit F
chr7_+_44200960 Show fit	9.15	ENST00000496112.5 ENST00000678359.1 ENST00000223369.3 ENST00000677090.1	YKT6 Links Ensembl NCBI GeneCards UniProt Show fit	YKT6 v-SNARE homolog
chr2_+_130181662 Show fit	9.10	ENST00000425361.5 ENST00000457492.5	MZT2B Links Ensembl NCBI GeneCards UniProt Show fit	mitotic spindle organizing protein 2B
chr11_-_62839564 Show fit	9.03	ENST00000311713.11 ENST00000278856.9	WDR74 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 74
chrX_-_20266995 Show fit	8.99	ENST00000644893.1 ENST00000642835.1 ENST00000646610.1	RPS6KA3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr5_-_81751103 Show fit	8.66	ENST00000514493.5 ENST00000320672.8 ENST00000615665.4	SSBP2 Links Ensembl NCBI GeneCards UniProt Show fit	single stranded DNA binding protein 2
chr19_-_12957198 Show fit	8.64	ENST00000316939.3	GADD45GIP1 Links Ensembl NCBI GeneCards UniProt Show fit	GADD45G interacting protein 1
chr11_-_65540610 Show fit	8.62	ENST00000532661.5	LTBP3 Links Ensembl NCBI GeneCards UniProt Show fit	latent transforming growth factor beta binding protein 3
chr2_-_69387188 Show fit	8.62	ENST00000674507.1 ENST00000357308.9	GFPT1 Links Ensembl NCBI GeneCards UniProt Show fit	glutamine--fructose-6-phosphate transaminase 1
chr1_-_114716729 Show fit	8.57	ENST00000369535.5	NRAS Links Ensembl NCBI GeneCards UniProt Show fit	NRAS proto-oncogene, GTPase
chr11_-_33722403 Show fit	8.56	ENST00000534312.5	ENSG00000284969.1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr1_+_109621088 Show fit	8.50	ENST00000369840.7 ENST00000358729.9 ENST00000476688.3	AMPD2 Links Ensembl NCBI GeneCards UniProt Show fit	adenosine monophosphate deaminase 2
chr1_-_197775435 Show fit	8.46	ENST00000620048.6	DENND1B Links Ensembl NCBI GeneCards UniProt Show fit	DENN domain containing 1B
chr20_+_58888779 Show fit	8.38	ENST00000488546.6 ENST00000667293.2 ENST00000481039.6 ENST00000467321.6	GNAS Links Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr12_-_48924919 Show fit	8.30	ENST00000444214.6	FKBP11 Links Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 11
chr11_+_69641146 Show fit	8.30	ENST00000227507.3 ENST00000536559.1	CCND1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin D1
chrX_-_20266606 Show fit	8.25	ENST00000643085.1 ENST00000645270.1 ENST00000644368.1	RPS6KA3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr12_+_15882373 Show fit	8.23	ENST00000419869.7 ENST00000025399.10	STRAP Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase receptor associated protein
chr19_+_54105923 Show fit	7.93	ENST00000420296.1	NDUFA3 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit A3
chr2_-_27322564 Show fit	7.77	ENST00000233545.6	MPV17 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial inner membrane protein MPV17
chr1_+_53014926 Show fit	7.69	ENST00000430330.6 ENST00000408941.7 ENST00000478274.6 ENST00000484100.5 ENST00000435345.6 ENST00000488965.1	SCP2 Links Ensembl NCBI GeneCards UniProt Show fit	sterol carrier protein 2
chr18_-_36129305 Show fit	7.68	ENST00000269187.10 ENST00000590986.5 ENST00000440549.6	SLC39A6 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 6
chr6_-_31582415 Show fit	7.41	ENST00000429299.3 ENST00000446745.2	LTB Links Ensembl NCBI GeneCards UniProt Show fit	lymphotoxin beta
chr22_-_37244417 Show fit	7.37	ENST00000405484.5 ENST00000441619.5 ENST00000406508.5	RAC2 Links Ensembl NCBI GeneCards UniProt Show fit	Rac family small GTPase 2
chr9_-_125189721 Show fit	7.33	ENST00000456642.1 ENST00000373547.9 ENST00000415905.5 ENST00000451402.5	PPP6C Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 6 catalytic subunit
chr14_-_21437235 Show fit	7.26	ENST00000430710.8 ENST00000646340.1 ENST00000646063.1	CHD8 Links Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 8
chr5_+_10353668 Show fit	7.25	ENST00000274140.10 ENST00000449913.6 ENST00000503788.5	MARCHF6 Links Ensembl NCBI GeneCards UniProt Show fit	membrane associated ring-CH-type finger 6
chr20_+_58889143 Show fit	7.23	ENST00000470512.6 ENST00000464788.6 ENST00000469431.6 ENST00000478585.6 ENST00000604005.6	GNAS Links Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr14_-_21437265 Show fit	7.16	ENST00000553622.5 ENST00000642518.1 ENST00000557364.6 ENST00000643469.1	CHD8 Links Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 8
chr1_+_193121950 Show fit	7.12	ENST00000367435.5	CDC73 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 73
chrX_-_154371210 Show fit	7.09	ENST00000369856.8 ENST00000422373.6 ENST00000360319.9	FLNA Links Ensembl NCBI GeneCards UniProt Show fit	filamin A
chr13_+_114235044 Show fit	6.94	ENST00000252457.9 ENST00000375308.5	CDC16 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 16
chr1_+_109620578 Show fit	6.93	ENST00000531203.6 ENST00000256578.8	AMPD2 Links Ensembl NCBI GeneCards UniProt Show fit	adenosine monophosphate deaminase 2
chr20_+_32358979 Show fit	6.84	ENST00000646985.1 ENST00000497249.6	ASXL1 Links Ensembl NCBI GeneCards UniProt Show fit	ASXL transcriptional regulator 1
chr5_-_81751022 Show fit	6.77	ENST00000509013.2 ENST00000505980.5 ENST00000509053.5	SSBP2 Links Ensembl NCBI GeneCards UniProt Show fit	single stranded DNA binding protein 2
chr16_+_28985043 Show fit	6.71	ENST00000395456.7 ENST00000564277.5 ENST00000630764.2 ENST00000354453.7	LAT Links Ensembl NCBI GeneCards UniProt Show fit	linker for activation of T cells
chr2_-_27323072 Show fit	6.67	ENST00000428910.5 ENST00000402722.5 ENST00000380044.6 ENST00000399052.8 ENST00000405076.5	MPV17 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial inner membrane protein MPV17
chr20_+_58889100 Show fit	6.63	ENST00000477931.5 ENST00000485673.6	GNAS Links Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr8_+_86514416 Show fit	6.61	ENST00000517490.6 ENST00000621783.4 ENST00000620393.4 ENST00000621526.4 ENST00000621245.4 ENST00000523469.5 ENST00000522240.1	CPNE3 Links Ensembl NCBI GeneCards UniProt Show fit	copine 3
chr19_-_10587219 Show fit	6.51	ENST00000591240.5 ENST00000589684.5 ENST00000591676.1 ENST00000250244.11 ENST00000590923.5	AP1M2 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit mu 2
chr5_+_96663010 Show fit	6.51	ENST00000506811.5 ENST00000514055.5 ENST00000508608.6	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr17_-_49677976 Show fit	6.40	ENST00000665825.1 ENST00000508805.5 ENST00000515508.6 ENST00000451526.6 ENST00000507970.5	SPOP Links Ensembl NCBI GeneCards UniProt Show fit	speckle type BTB/POZ protein
chr1_-_50960230 Show fit	6.33	ENST00000396153.7	FAF1 Links Ensembl NCBI GeneCards UniProt Show fit	Fas associated factor 1
chr1_+_193122151 Show fit	6.31	ENST00000635846.1	CDC73 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 73
chr1_-_25905989 Show fit	6.31	ENST00000399728.5	STMN1 Links Ensembl NCBI GeneCards UniProt Show fit	stathmin 1
chr5_+_96662969 Show fit	6.29	ENST00000514845.5 ENST00000675663.1	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr1_-_206921987 Show fit	6.20	ENST00000530505.1 ENST00000442471.4	FCMR Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgM receptor
chr12_+_53295506 Show fit	6.15	ENST00000549759.2 ENST00000628881.2 ENST00000351500.7 ENST00000550846.5 ENST00000334478.9 ENST00000547130.6 ENST00000552742.6	PFDN5 Links Ensembl NCBI GeneCards UniProt Show fit	prefoldin subunit 5
chr16_-_20741792 Show fit	6.14	ENST00000396083.7	THUMPD1 Links Ensembl NCBI GeneCards UniProt Show fit	THUMP domain containing 1
chr17_+_68512878 Show fit	5.96	ENST00000585981.5 ENST00000589480.5 ENST00000585815.5	PRKAR1A Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit alpha
chr11_-_33722710 Show fit	5.96	ENST00000415002.7 ENST00000437761.6 ENST00000445143.6	CD59 Links Ensembl NCBI GeneCards UniProt Show fit	CD59 molecule (CD59 blood group)
chr5_-_37371061 Show fit	5.83	ENST00000513532.1 ENST00000231498.8	NUP155 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 155
chr20_-_21514046 Show fit	5.82	ENST00000377142.5	NKX2-2 Links Ensembl NCBI GeneCards UniProt Show fit	NK2 homeobox 2
chr3_-_108222383 Show fit	5.79	ENST00000264538.4	IFT57 Links Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 57
chr12_-_79690957 Show fit	5.76	ENST00000328827.9	PAWR Links Ensembl NCBI GeneCards UniProt Show fit	pro-apoptotic WT1 regulator
chr12_+_69739370 Show fit	5.73	ENST00000550536.5 ENST00000362025.9	RAB3IP Links Ensembl NCBI GeneCards UniProt Show fit	RAB3A interacting protein
chr1_+_42682954 Show fit	5.68	ENST00000436427.1	YBX1 Links Ensembl NCBI GeneCards UniProt Show fit	Y-box binding protein 1
chr12_+_6951345 Show fit	5.60	ENST00000318974.14 ENST00000541698.5 ENST00000542462.1	PTPN6 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr10_-_97498378 Show fit	5.55	ENST00000327238.14 ENST00000437002.5 ENST00000438925.7 ENST00000422685.5	MMS19 Links Ensembl NCBI GeneCards UniProt Show fit	MMS19 homolog, cytosolic iron-sulfur assembly component
chr17_-_42979993 Show fit	5.54	ENST00000409103.5 ENST00000360221.8 ENST00000454303.1 ENST00000591916.7 ENST00000451885.3	PTGES3L-AARSD1 Links Ensembl NCBI GeneCards UniProt Show fit PTGES3L Links Ensembl NCBI GeneCards UniProt Show fit	PTGES3L-AARSD1 readthrough prostaglandin E synthase 3 like
chr1_-_206921867 Show fit	5.36	ENST00000628511.2 ENST00000367091.8	FCMR Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgM receptor
chr7_+_6374491 Show fit	5.34	ENST00000348035.9 ENST00000356142.4	RAC1 Links Ensembl NCBI GeneCards UniProt Show fit	Rac family small GTPase 1
chr22_-_19431692 Show fit	5.32	ENST00000340170.8 ENST00000263208.5	HIRA Links Ensembl NCBI GeneCards UniProt Show fit	histone cell cycle regulator
chr1_-_27914513 Show fit	5.24	ENST00000313433.11 ENST00000373912.8 ENST00000444045.1	RPA2 Links Ensembl NCBI GeneCards UniProt Show fit	replication protein A2
chr20_-_63969890 Show fit	5.23	ENST00000369888.6	ZNF512B Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 512B
chr2_+_30231524 Show fit	5.20	ENST00000395323.9 ENST00000406087.5 ENST00000404397.5	LBH Links Ensembl NCBI GeneCards UniProt Show fit	LBH regulator of WNT signaling pathway
chr22_-_38872206 Show fit	5.14	ENST00000407418.8 ENST00000216083.6	CBX6 Links Ensembl NCBI GeneCards UniProt Show fit	chromobox 6
chr17_-_49678074 Show fit	5.12	ENST00000505581.5 ENST00000504102.6 ENST00000514121.6 ENST00000393328.6 ENST00000509079.6 ENST00000347630.6	SPOP Links Ensembl NCBI GeneCards UniProt Show fit	speckle type BTB/POZ protein
chr11_+_66052331 Show fit	5.05	ENST00000528302.5 ENST00000322535.11 ENST00000524627.5 ENST00000533595.5 ENST00000530322.5	SF3B2 Links Ensembl NCBI GeneCards UniProt Show fit	splicing factor 3b subunit 2
chr1_+_235327344 Show fit	4.99	ENST00000488594.5	GGPS1 Links Ensembl NCBI GeneCards UniProt Show fit	geranylgeranyl diphosphate synthase 1
chr17_+_68512379 Show fit	4.92	ENST00000392711.5 ENST00000585427.5 ENST00000589228.6 ENST00000536854.6 ENST00000588702.5 ENST00000589309.5	PRKAR1A Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit alpha
chr16_-_1773113 Show fit	4.86	ENST00000397375.7 ENST00000177742.7	MRPS34 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S34
chr14_+_30874541 Show fit	4.85	ENST00000396618.9 ENST00000644874.2 ENST00000555117.2 ENST00000475087.5	COCH Links Ensembl NCBI GeneCards UniProt Show fit	cochlin
chr12_+_4321197 Show fit	4.84	ENST00000179259.6	TIGAR Links Ensembl NCBI GeneCards UniProt Show fit	TP53 induced glycolysis regulatory phosphatase
chr12_+_6951271 Show fit	4.79	ENST00000456013.5	PTPN6 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr3_+_58008350 Show fit	4.78	ENST00000490882.5 ENST00000358537.7 ENST00000429972.6 ENST00000682871.1 ENST00000295956.9	FLNB Links Ensembl NCBI GeneCards UniProt Show fit	filamin B
chr19_+_40807112 Show fit	4.77	ENST00000595621.1 ENST00000595051.1	EGLN2 Links Ensembl NCBI GeneCards UniProt Show fit	egl-9 family hypoxia inducible factor 2
chr9_+_19049385 Show fit	4.77	ENST00000380527.3	RRAGA Links Ensembl NCBI GeneCards UniProt Show fit	Ras related GTP binding A
chr14_+_23306816 Show fit	4.69	ENST00000678311.1 ENST00000557579.2 ENST00000250405.10 ENST00000679000.1 ENST00000557236.6 ENST00000678502.1 ENST00000553781.5	BCL2L2 Links Ensembl NCBI GeneCards UniProt Show fit BCL2L2-PABPN1 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2 like 2 BCL2L2-PABPN1 readthrough
chr17_-_81918134 Show fit	4.37	ENST00000328666.11	SIRT7 Links Ensembl NCBI GeneCards UniProt Show fit	sirtuin 7
chr10_-_80205520 Show fit	4.29	ENST00000422982.8	ANXA11 Links Ensembl NCBI GeneCards UniProt Show fit	annexin A11
chr16_+_28985251 Show fit	4.17	ENST00000360872.9 ENST00000566177.5	LAT Links Ensembl NCBI GeneCards UniProt Show fit	linker for activation of T cells
chr14_+_30874745 Show fit	4.13	ENST00000556908.5 ENST00000555881.5 ENST00000460581.6 ENST00000643575.1	COCH Links Ensembl NCBI GeneCards UniProt Show fit	cochlin
chr3_-_11720690 Show fit	4.11	ENST00000426568.5	VGLL4 Links Ensembl NCBI GeneCards UniProt Show fit	vestigial like family member 4
chr4_-_151015713 Show fit	4.09	ENST00000357115.9	LRBA Links Ensembl NCBI GeneCards UniProt Show fit	LPS responsive beige-like anchor protein
chr22_-_28800042 Show fit	4.08	ENST00000405219.7	XBP1 Links Ensembl NCBI GeneCards UniProt Show fit	X-box binding protein 1
chr6_+_85450033 Show fit	4.06	ENST00000257770.8 ENST00000369646.7	NT5E Links Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase ecto
chr2_-_219571241 Show fit	3.97	ENST00000373876.5 ENST00000603926.5 ENST00000373873.8 ENST00000289656.3	OBSL1 Links Ensembl NCBI GeneCards UniProt Show fit	obscurin like cytoskeletal adaptor 1
chr17_-_8630749 Show fit	3.91	ENST00000379980.8 ENST00000269243.8	MYH10 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 10
chr22_+_41092585 Show fit	3.85	ENST00000263253.9	EP300 Links Ensembl NCBI GeneCards UniProt Show fit	E1A binding protein p300
chrX_+_47585212 Show fit	3.83	ENST00000445623.1	TIMP1 Links Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 1
chr17_-_64020566 Show fit	3.79	ENST00000578313.5 ENST00000584084.1 ENST00000579687.5 ENST00000578379.5 ENST00000578892.5 ENST00000579788.6 ENST00000412356.5 ENST00000418105.5	ICAM2 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 2
chr4_-_151015263 Show fit	3.75	ENST00000510413.5 ENST00000507224.5 ENST00000651943.2	LRBA Links Ensembl NCBI GeneCards UniProt Show fit	LPS responsive beige-like anchor protein
chr1_-_27914717 Show fit	3.72	ENST00000373909.7	RPA2 Links Ensembl NCBI GeneCards UniProt Show fit	replication protein A2
chr16_+_29461386 Show fit	3.70	ENST00000565290.5	SULT1A4 Links Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1A member 4
chr9_-_133149334 Show fit	3.69	ENST00000393160.7	RALGDS Links Ensembl NCBI GeneCards UniProt Show fit	ral guanine nucleotide dissociation stimulator
chr2_-_24360299 Show fit	3.69	ENST00000361999.7	ITSN2 Links Ensembl NCBI GeneCards UniProt Show fit	intersectin 2
chr17_-_8630713 Show fit	3.65	ENST00000411957.1 ENST00000360416.8	MYH10 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 10
chr17_-_64020544 Show fit	3.60	ENST00000583366.5	ICAM2 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 2
chr5_-_81751085 Show fit	3.57	ENST00000515395.5	SSBP2 Links Ensembl NCBI GeneCards UniProt Show fit	single stranded DNA binding protein 2
chr1_-_32702736 Show fit	3.53	ENST00000373484.4 ENST00000409190.8	SYNC Links Ensembl NCBI GeneCards UniProt Show fit	syncoilin, intermediate filament protein
chr17_-_44220963 Show fit	3.51	ENST00000343638.9	UBTF Links Ensembl NCBI GeneCards UniProt Show fit	upstream binding transcription factor
chr1_-_32336224 Show fit	3.39	ENST00000329421.8	MARCKSL1 Links Ensembl NCBI GeneCards UniProt Show fit	MARCKS like 1
chr11_-_417304 Show fit	3.39	ENST00000397632.7	SIGIRR Links Ensembl NCBI GeneCards UniProt Show fit	single Ig and TIR domain containing
chr9_-_26892732 Show fit	3.38	ENST00000333916.8 ENST00000520187.1	CAAP1 Links Ensembl NCBI GeneCards UniProt Show fit	caspase activity and apoptosis inhibitor 1
chr20_+_48921701 Show fit	3.38	ENST00000371917.5	ARFGEF2 Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor guanine nucleotide exchange factor 2
chrX_+_136497586 Show fit	3.31	ENST00000218364.5	HTATSF1 Links Ensembl NCBI GeneCards UniProt Show fit	HIV-1 Tat specific factor 1
chr3_-_11720728 Show fit	3.26	ENST00000445411.5 ENST00000273038.7	VGLL4 Links Ensembl NCBI GeneCards UniProt Show fit	vestigial like family member 4
chr16_-_73048104 Show fit	3.21	ENST00000268489.10	ZFHX3 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger homeobox 3
chr19_-_14206168 Show fit	3.21	ENST00000361434.7 ENST00000340736.10	ADGRL1 Links Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor L1
chr17_-_44220831 Show fit	3.19	ENST00000527034.5	UBTF Links Ensembl NCBI GeneCards UniProt Show fit	upstream binding transcription factor
chr13_+_114235066 Show fit	3.12	ENST00000252458.6	CDC16 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 16
chr12_+_69738853 Show fit	3.12	ENST00000247833.12 ENST00000378815.10 ENST00000483530.6	RAB3IP Links Ensembl NCBI GeneCards UniProt Show fit	RAB3A interacting protein
chr14_-_105168753 Show fit	3.11	ENST00000331782.8 ENST00000347004.2	JAG2 Links Ensembl NCBI GeneCards UniProt Show fit	jagged canonical Notch ligand 2
chr19_+_1407517 Show fit	3.06	ENST00000336761.10 ENST00000233078.9 ENST00000592522.5	DAZAP1 Links Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 1
chr11_+_43680686 Show fit	3.00	ENST00000531185.5 ENST00000278353.10	HSD17B12 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxysteroid 17-beta dehydrogenase 12
chr16_+_30201057 Show fit	2.97	ENST00000569485.5	SULT1A3 Links Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1A member 3
chr11_+_849816 Show fit	2.95	ENST00000527644.1	TSPAN4 Links Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 4
chr22_+_46674593 Show fit	2.89	ENST00000408031.1	GRAMD4 Links Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 4
chr12_+_100473916 Show fit	2.89	ENST00000549996.5	NR1H4 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group H member 4
chr7_+_30969533 Show fit	2.88	ENST00000409904.7 ENST00000409316.5	GHRHR Links Ensembl NCBI GeneCards UniProt Show fit	growth hormone releasing hormone receptor
chr1_+_109619827 Show fit	2.85	ENST00000667949.2 ENST00000342115.8 ENST00000528667.7	AMPD2 Links Ensembl NCBI GeneCards UniProt Show fit	adenosine monophosphate deaminase 2
chr17_+_82031643 Show fit	2.69	ENST00000306897.9	RAC3 Links Ensembl NCBI GeneCards UniProt Show fit	Rac family small GTPase 3
chr14_+_22543179 Show fit	2.66	ENST00000390534.1	TRAJ3 Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 3
chrX_+_37685773 Show fit	2.65	ENST00000378616.5	XK Links Ensembl NCBI GeneCards UniProt Show fit	X-linked Kx blood group
chr9_+_137188646 Show fit	2.62	ENST00000322310.10	SSNA1 Links Ensembl NCBI GeneCards UniProt Show fit	SS nuclear autoantigen 1
chr17_-_56961014 Show fit	2.56	ENST00000240316.5	COIL Links Ensembl NCBI GeneCards UniProt Show fit	coilin
chr4_-_177442427 Show fit	2.55	ENST00000264595.7	AGA Links Ensembl NCBI GeneCards UniProt Show fit	aspartylglucosaminidase
chr3_+_46979659 Show fit	2.52	ENST00000450053.8	NBEAL2 Links Ensembl NCBI GeneCards UniProt Show fit	neurobeachin like 2
chr6_-_56851888 Show fit	2.51	ENST00000312431.10 ENST00000520645.5	DST Links Ensembl NCBI GeneCards UniProt Show fit	dystonin
chr9_+_137188697 Show fit	2.36	ENST00000464553.2	SSNA1 Links Ensembl NCBI GeneCards UniProt Show fit	SS nuclear autoantigen 1
chr10_+_134465 Show fit	2.34	ENST00000439456.5 ENST00000397962.8 ENST00000309776.8 ENST00000397959.7	ZMYND11 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger MYND-type containing 11
chr5_-_173235194 Show fit	2.25	ENST00000329198.5 ENST00000521848.1	NKX2-5 Links Ensembl NCBI GeneCards UniProt Show fit	NK2 homeobox 5
chr7_-_16804987 Show fit	2.22	ENST00000401412.5 ENST00000419304.7	AGR2 Links Ensembl NCBI GeneCards UniProt Show fit	anterior gradient 2, protein disulphide isomerase family member
chr12_+_100473708 Show fit	2.20	ENST00000548884.5 ENST00000392986.8	NR1H4 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group H member 4
chr2_-_174597795 Show fit	2.19	ENST00000679041.1	WIPF1 Links Ensembl NCBI GeneCards UniProt Show fit	WAS/WASL interacting protein family member 1
chr19_+_1407653 Show fit	2.12	ENST00000587079.5	DAZAP1 Links Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 1
chr9_-_120793343 Show fit	2.11	ENST00000684047.1	FBXW2 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 2
chr16_+_12901591 Show fit	2.10	ENST00000558583.3	SHISA9 Links Ensembl NCBI GeneCards UniProt Show fit	shisa family member 9
chr2_-_69387130 Show fit	2.09	ENST00000674438.1	GFPT1 Links Ensembl NCBI GeneCards UniProt Show fit	glutamine--fructose-6-phosphate transaminase 1
chr11_-_417385 Show fit	2.07	ENST00000332725.7	SIGIRR Links Ensembl NCBI GeneCards UniProt Show fit	single Ig and TIR domain containing
chrX_+_46912276 Show fit	2.03	ENST00000424392.5 ENST00000611250.4	JADE3 Links Ensembl NCBI GeneCards UniProt Show fit	jade family PHD finger 3
chr4_-_144019287 Show fit	2.02	ENST00000638448.1 ENST00000513128.5 ENST00000506516.6 ENST00000429670.3 ENST00000502664.6	GYPB Links Ensembl NCBI GeneCards UniProt Show fit	glycophorin B (MNS blood group)
chr3_-_126056786 Show fit	1.98	ENST00000383598.6	SLC41A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 41 member 3
chrX_-_154516183 Show fit	1.97	ENST00000442929.1 ENST00000426266.5 ENST00000447601.7 ENST00000359889.9 ENST00000369641.7 ENST00000322269.10 ENST00000419205.5	FAM3A Links Ensembl NCBI GeneCards UniProt Show fit	FAM3 metabolism regulating signaling molecule A
chr1_-_61725121 Show fit	1.96	ENST00000371177.2 ENST00000606498.5	TM2D1 Links Ensembl NCBI GeneCards UniProt Show fit	TM2 domain containing 1
chr9_-_120793377 Show fit	1.94	ENST00000684001.1 ENST00000684405.1 ENST00000608872.6	FBXW2 Links Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 2
chr4_-_108166750 Show fit	1.92	ENST00000515500.5	LEF1 Links Ensembl NCBI GeneCards UniProt Show fit	lymphoid enhancer binding factor 1
chr19_+_40799501 Show fit	1.89	ENST00000406058.6 ENST00000593726.5	EGLN2 Links Ensembl NCBI GeneCards UniProt Show fit	egl-9 family hypoxia inducible factor 2
chr20_-_38033424 Show fit	1.84	ENST00000373447.8 ENST00000373448.6	TTI1 Links Ensembl NCBI GeneCards UniProt Show fit	TELO2 interacting protein 1

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.7	26.0	GO:0034238	macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
7.8	39.2	GO:0006177	GMP biosynthetic process(GO:0006177)
6.8	33.8	GO:0033383	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
4.9	14.8	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
4.5	13.4	GO:0034402	recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
4.1	12.3	GO:0009085	lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
3.8	19.0	GO:0070197	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
3.2	26.0	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
3.0	12.2	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
2.9	8.6	GO:1902462	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
2.9	34.4	GO:0070495	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
2.8	11.3	GO:0010796	regulation of multivesicular body size(GO:0010796)
2.7	10.9	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
2.5	7.6	GO:0021592	fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
2.5	32.7	GO:0021769	orbitofrontal cortex development(GO:0021769)
2.4	7.1	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
2.3	11.5	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
2.3	16.1	GO:0060011	Sertoli cell proliferation(GO:0060011)
2.2	20.2	GO:0060762	positive regulation of exit from mitosis(GO:0031536) negative regulation of mammary gland epithelial cell proliferation(GO:0033600) thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
2.1	10.4	GO:0033277	abortive mitotic cell cycle(GO:0033277)
2.0	4.1	GO:0006196	AMP catabolic process(GO:0006196)
1.9	5.8	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.8	18.3	GO:0032264	IMP salvage(GO:0032264)
1.8	5.3	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
1.7	26.1	GO:0032836	glomerular basement membrane development(GO:0032836)
1.7	19.1	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
1.7	6.8	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
1.6	4.8	GO:0043465	fermentation(GO:0006113) regulation of fermentation(GO:0043465)
1.5	6.0	GO:0001080	nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
1.5	23.6	GO:2000828	parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
1.5	4.4	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
1.4	14.4	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
1.4	4.1	GO:0035470	positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
1.3	7.7	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.2	8.6	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
1.2	6.0	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
1.1	7.4	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
1.0	5.2	GO:2000035	positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
1.0	3.1	GO:0061760	antifungal innate immune response(GO:0061760)
1.0	14.4	GO:2000774	positive regulation of cellular senescence(GO:2000774)
1.0	5.0	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
1.0	4.9	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) N-terminal peptidyl-lysine acetylation(GO:0018076)
1.0	9.7	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
1.0	2.9	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.9	8.4	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.9	16.9	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.9	5.5	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.9	10.0	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.9	20.9	GO:0060972	left/right pattern formation(GO:0060972)
0.9	7.7	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.8	26.7	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.8	10.9	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.8	8.3	GO:0033327	Leydig cell differentiation(GO:0033327)
0.7	8.5	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.7	10.5	GO:0000338	protein deneddylation(GO:0000338)
0.7	5.6	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.6	3.2	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.6	10.3	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.6	3.8	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.6	10.7	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.6	3.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.6	1.7	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.6	12.8	GO:2000674	regulation of type B pancreatic cell apoptotic process(GO:2000674) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.6	10.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.5	3.0	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.5	5.8	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.5	8.2	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.4	2.2	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.4	15.7	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.4	6.7	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.4	5.7	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.4	2.7	GO:0010961	cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
0.4	6.3	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.4	1.8	GO:0071287	peptidyl-aspartic acid modification(GO:0018197) cellular response to manganese ion(GO:0071287)
0.4	5.7	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3	9.0	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569) regulation of DNA damage checkpoint(GO:2000001)
0.3	4.4	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.3	3.1	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.3	3.7	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.3	5.3	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.3	11.5	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.3	1.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.3	1.0	GO:0018032	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.3	9.2	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.3	4.8	GO:0003334	keratinocyte development(GO:0003334)
0.3	1.0	GO:0043335	protein unfolding(GO:0043335)
0.2	1.2	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2	14.1	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.2	2.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.2	7.5	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.2	2.5	GO:0008090	retrograde axonal transport(GO:0008090)
0.2	10.9	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.2	4.3	GO:0032506	cytokinetic process(GO:0032506)
0.2	23.5	GO:0006903	vesicle targeting(GO:0006903)
0.2	5.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2	7.8	GO:0000154	rRNA modification(GO:0000154)
0.2	1.0	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.2	3.0	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	3.0	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.2	0.7	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.2	10.9	GO:1903146	regulation of mitophagy(GO:1903146)
0.2	8.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	49.6	GO:0016579	protein deubiquitination(GO:0016579)
0.1	2.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	3.7	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.9	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1	7.9	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	8.8	GO:0002279	mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.1	11.6	GO:0006968	cellular defense response(GO:0006968)
0.1	1.7	GO:0002517	T cell tolerance induction(GO:0002517)
0.1	1.1	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1	3.2	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.1	9.0	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.1	1.7	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.1	3.7	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1	0.9	GO:0000012	single strand break repair(GO:0000012)
0.1	5.0	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.1	7.4	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1	1.0	GO:0015868	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1	3.5	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	2.5	GO:0030220	platelet formation(GO:0030220)
0.1	9.4	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1	12.3	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.1	1.4	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.1	4.9	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.1	5.5	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.5	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.5	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
0.1	0.5	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.1	0.8	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	6.2	GO:0045089	positive regulation of innate immune response(GO:0045089)
0.0	0.5	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.5	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	1.0	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.8	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	12.8	GO:0009615	response to virus(GO:0009615)
0.0	1.0	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.6	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.4	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	1.4	GO:0097202	activation of cysteine-type endopeptidase activity(GO:0097202)
0.0	0.2	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0	1.7	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.3	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.5	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.1	GO:0050930	induction of positive chemotaxis(GO:0050930)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.6	16.9	GO:0045323	interleukin-1 receptor complex(GO:0045323)
3.0	9.1	GO:0097441	basilar dendrite(GO:0097441)
2.3	6.8	GO:0035517	PR-DUB complex(GO:0035517)
2.3	11.3	GO:0098837	postsynaptic recycling endosome(GO:0098837)
2.2	10.9	GO:0089701	U2AF(GO:0089701)
1.9	5.8	GO:0044611	nuclear pore inner ring(GO:0044611)
1.9	11.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.6	32.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
1.5	7.6	GO:0097513	myosin II filament(GO:0097513)
1.5	19.0	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.4	7.1	GO:0031523	Myb complex(GO:0031523)
1.4	5.6	GO:0071817	MMXD complex(GO:0071817)
1.3	16.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
1.2	13.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
1.1	9.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.1	14.8	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
1.1	4.4	GO:1990393	3M complex(GO:1990393)
1.0	32.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.9	10.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.9	9.7	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.9	6.1	GO:0016272	prefoldin complex(GO:0016272)
0.8	4.9	GO:0005879	axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.8	18.7	GO:0030992	intraciliary transport particle B(GO:0030992)
0.8	4.8	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.7	9.7	GO:0005869	dynactin complex(GO:0005869)
0.7	8.2	GO:0032797	SMN complex(GO:0032797)
0.6	9.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.6	31.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.5	10.9	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.5	5.7	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.5	2.5	GO:0031673	H zone(GO:0031673)
0.5	9.0	GO:0005662	DNA replication factor A complex(GO:0005662)
0.4	9.0	GO:0005686	U2 snRNP(GO:0005686)
0.4	1.8	GO:0031166	integral component of vacuolar membrane(GO:0031166)
0.4	39.2	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.4	7.4	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4	11.5	GO:0005680	anaphase-promoting complex(GO:0005680)
0.4	14.4	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4	33.7	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.4	19.5	GO:0008180	COP9 signalosome(GO:0008180)
0.4	6.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3	1.6	GO:0070761	pre-snoRNP complex(GO:0070761)
0.3	21.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.3	9.0	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.3	3.1	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.2	19.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.2	1.8	GO:0031931	TORC1 complex(GO:0031931)
0.2	17.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	6.0	GO:0005719	nuclear euchromatin(GO:0005719)
0.2	33.3	GO:0016363	nuclear matrix(GO:0016363)
0.1	6.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	7.1	GO:0030131	clathrin adaptor complex(GO:0030131)
0.1	12.2	GO:0000502	proteasome complex(GO:0000502)
0.1	7.9	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	6.2	GO:0070821	tertiary granule membrane(GO:0070821)
0.1	8.6	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1	6.8	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	0.2	GO:0070435	Shc-EGFR complex(GO:0070435)
0.1	20.9	GO:0030496	midbody(GO:0030496)
0.1	0.4	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1	1.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	2.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	7.9	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.1	6.6	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	1.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	6.6	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.1	0.9	GO:0033270	paranode region of axon(GO:0033270)
0.1	11.2	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1	8.5	GO:0005903	brush border(GO:0005903)
0.1	1.0	GO:0005922	connexon complex(GO:0005922)
0.1	10.5	GO:0044452	nucleolar part(GO:0044452)
0.0	10.3	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.5	GO:0061574	ASAP complex(GO:0061574)
0.0	0.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	3.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	18.5	GO:0005874	microtubule(GO:0005874)
0.0	1.0	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.5	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	3.5	GO:0005882	intermediate filament(GO:0005882)
0.0	2.6	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	9.8	GO:0005635	nuclear envelope(GO:0005635)
0.0	2.6	GO:0016605	PML body(GO:0016605)
0.0	4.9	GO:0005840	ribosome(GO:0005840)
0.0	0.5	GO:0031941	filamentous actin(GO:0031941)
0.0	2.3	GO:0032993	protein-DNA complex(GO:0032993)
0.0	10.8	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.4	GO:1902711	GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.8	39.2	GO:0003938	IMP dehydrogenase activity(GO:0003938)
6.8	33.8	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
5.2	20.7	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
4.8	43.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
4.7	14.2	GO:0001069	regulatory region RNA binding(GO:0001069)
3.3	19.6	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
3.0	12.2	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
2.8	16.9	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
2.7	10.9	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
2.7	10.7	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
2.6	7.7	GO:0070538	oleic acid binding(GO:0070538)
2.0	18.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.6	4.8	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
1.6	10.9	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.5	6.0	GO:1902122	chenodeoxycholic acid binding(GO:1902122)
1.5	4.4	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
1.4	7.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
1.3	12.8	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.2	8.4	GO:0019826	oxygen sensor activity(GO:0019826)
1.1	10.0	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
1.0	26.7	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
1.0	23.6	GO:0051430	mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.0	6.7	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
1.0	10.5	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.9	19.0	GO:0043495	protein anchor(GO:0043495)
0.8	16.1	GO:0051400	BH domain binding(GO:0051400)
0.8	4.9	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.8	3.2	GO:0016524	latrotoxin receptor activity(GO:0016524)
0.8	5.3	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.8	3.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.7	3.0	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.7	17.5	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.7	2.9	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.6	10.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.6	26.0	GO:0043236	laminin binding(GO:0043236)
0.6	9.0	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.6	11.9	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.6	10.5	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.6	9.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.5	10.9	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.5	21.4	GO:0019956	chemokine binding(GO:0019956)
0.5	6.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.5	22.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.5	11.2	GO:0008242	omega peptidase activity(GO:0008242)
0.5	9.1	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4	13.4	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.4	10.3	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4	20.6	GO:0030331	estrogen receptor binding(GO:0030331)
0.4	9.6	GO:0031489	myosin V binding(GO:0031489)
0.4	7.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.4	14.8	GO:0017091	AU-rich element binding(GO:0017091)
0.4	1.8	GO:1903135	cupric ion binding(GO:1903135)
0.4	27.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3	7.6	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.3	8.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3	4.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.3	0.9	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3	4.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.3	5.2	GO:0035613	RNA stem-loop binding(GO:0035613)
0.3	8.3	GO:0070064	proline-rich region binding(GO:0070064)
0.3	8.5	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3	3.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.3	1.0	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2	5.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.2	4.9	GO:0050811	GABA receptor binding(GO:0050811)
0.2	12.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2	5.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	1.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2	1.6	GO:1990226	histone methyltransferase binding(GO:1990226)
0.2	6.0	GO:0001848	complement binding(GO:0001848)
0.2	3.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	6.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.2	7.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	0.4	GO:0004577	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.1	7.9	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	1.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	32.4	GO:0051015	actin filament binding(GO:0051015)
0.1	4.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	15.6	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	1.0	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	5.5	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	17.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	7.1	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	29.5	GO:0003924	GTPase activity(GO:0003924)
0.1	5.3	GO:0031491	nucleosome binding(GO:0031491)
0.1	7.3	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	8.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	1.7	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1	1.0	GO:0005243	gap junction channel activity(GO:0005243)
0.1	3.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	5.4	GO:0005518	collagen binding(GO:0005518)
0.0	2.3	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	15.6	GO:0015631	tubulin binding(GO:0015631)
0.0	1.0	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	2.6	GO:0043621	protein self-association(GO:0043621)
0.0	1.7	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	4.5	GO:0017124	SH3 domain binding(GO:0017124)
0.0	3.2	GO:0001046	core promoter sequence-specific DNA binding(GO:0001046)
0.0	1.0	GO:0005158	insulin receptor binding(GO:0005158)
0.0	4.9	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	1.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	2.1	GO:0030165	PDZ domain binding(GO:0030165)
0.0	4.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.5	GO:0070888	E-box binding(GO:0070888)
0.0	0.4	GO:0004890	GABA-A receptor activity(GO:0004890)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	42.7	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.8	8.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.8	32.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.6	11.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.6	28.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.5	16.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.4	34.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.4	8.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3	24.5	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.2	10.9	PID ATM PATHWAY	ATM pathway
0.2	17.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.2	9.0	PID ATR PATHWAY	ATR signaling pathway
0.2	21.1	PID E2F PATHWAY	E2F transcription factor network
0.2	19.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.2	10.9	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.2	11.5	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.2	7.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	8.2	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	6.7	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.1	10.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	5.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	12.1	PID P73PATHWAY	p73 transcription factor network
0.1	1.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	2.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	11.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	6.5	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	10.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	19.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	6.3	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.1	3.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	1.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	2.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	4.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	2.8	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	3.2	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.7	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	39.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.9	16.9	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
1.2	11.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
1.2	14.8	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.9	8.6	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.8	33.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.8	6.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.8	12.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.8	36.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.7	10.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.7	29.0	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.7	23.6	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.6	9.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.6	14.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.5	22.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.5	11.5	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.4	13.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.4	9.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.4	6.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4	7.7	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.4	7.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.4	3.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3	10.9	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.3	4.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3	4.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.3	6.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	8.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3	14.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.3	11.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.3	31.8	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.2	9.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	25.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.2	8.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	6.1	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2	9.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.2	3.7	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	2.9	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.1	5.8	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.7	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	3.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	3.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	7.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	1.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	7.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	4.8	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	1.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	5.0	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	1.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.1	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	2.8	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.9	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	1.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein