ISMARA results: HNF1A

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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HNF1A_HNF1B

Z-value: 2.08

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Transcription factors associated with HNF1A_HNF1B

Gene Symbol	Gene ID	Gene Info
HNF1A Ensembl NCBI GeneCards UniProt	ENSG00000135100.19	HNF1A
HNF1B Ensembl NCBI GeneCards UniProt	ENSG00000275410.6	HNF1B

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HNF1A	hg38_v1_chr12_+_120978686_120978749	0.52	9.9e-17	Click!
HNF1B	hg38_v1_chr17_-_37745018_37745069	0.41	3.8e-10	Click!

Activity profile of HNF1A_HNF1B motif

Sorted Z-values of HNF1A_HNF1B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF1A_HNF1B

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr17_-_66229380 Show fit	61.70	ENST00000205948.11	APOH Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein H
chr4_-_71784046 Show fit	60.20	ENST00000513476.5 ENST00000273951.13	GC Ensembl NCBI GeneCards UniProt Show fit	GC vitamin D binding protein
chr4_+_73436198 Show fit	50.59	ENST00000395792.7	AFP Ensembl NCBI GeneCards UniProt Show fit	alpha fetoprotein
chr4_+_73436244 Show fit	50.18	ENST00000226359.2	AFP Ensembl NCBI GeneCards UniProt Show fit	alpha fetoprotein
chr6_+_160702238 Show fit	41.49	ENST00000366924.6 ENST00000308192.14 ENST00000418964.1	PLG Ensembl NCBI GeneCards UniProt Show fit	plasminogen
chr4_+_154563003 Show fit	39.31	ENST00000302068.9 ENST00000509493.1	FGB Ensembl NCBI GeneCards UniProt Show fit	fibrinogen beta chain
chr19_-_35812838 Show fit	36.87	ENST00000653904.2	PRODH2 Ensembl NCBI GeneCards UniProt Show fit	proline dehydrogenase 2
chr14_-_94388589 Show fit	35.71	ENST00000402629.1 ENST00000556091.1 ENST00000393087.9 ENST00000554720.1	SERPINA1 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 1
chr4_-_154590735 Show fit	34.86	ENST00000403106.8 ENST00000622532.1 ENST00000651975.1	FGA Ensembl NCBI GeneCards UniProt Show fit	fibrinogen alpha chain
chr4_+_73404255 Show fit	33.24	ENST00000621628.4 ENST00000621085.4 ENST00000415165.6 ENST00000295897.9 ENST00000503124.5 ENST00000509063.5 ENST00000401494.7	ALB Ensembl NCBI GeneCards UniProt Show fit	albumin
chr2_+_233760265 Show fit	32.96	ENST00000305208.10 ENST00000360418.4	UGT1A1 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A1
chr2_+_233692881 Show fit	32.06	ENST00000305139.11	UGT1A6 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A6
chr4_+_73481737 Show fit	31.88	ENST00000226355.5	AFM Ensembl NCBI GeneCards UniProt Show fit	afamin
chr9_-_121050264 Show fit	28.47	ENST00000223642.3	C5 Ensembl NCBI GeneCards UniProt Show fit	complement C5
chr15_+_58431985 Show fit	28.13	ENST00000433326.2 ENST00000299022.10	LIPC Ensembl NCBI GeneCards UniProt Show fit	lipase C, hepatic type
chr7_-_50565381 Show fit	27.92	ENST00000444124.7	DDC Ensembl NCBI GeneCards UniProt Show fit	dopa decarboxylase
chr16_-_20576277 Show fit	27.41	ENST00000566384.5 ENST00000565232.5 ENST00000567001.5 ENST00000565322.5 ENST00000569344.5 ENST00000329697.10 ENST00000568882.1	ACSM2B Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 2B
chr1_+_207104226 Show fit	22.40	ENST00000367070.8	C4BPA Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein alpha
chr19_+_49513353 Show fit	22.03	ENST00000596975.5	FCGRT Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG receptor and transporter
chr6_-_160664270 Show fit	20.74	ENST00000316300.10	LPA Ensembl NCBI GeneCards UniProt Show fit	lipoprotein(a)
chr7_+_45888360 Show fit	20.70	ENST00000457280.5	IGFBP1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 1
chr16_+_20451461 Show fit	20.55	ENST00000574251.5 ENST00000573854.6	ACSM2A Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 2A
chr8_-_17895487 Show fit	20.46	ENST00000427924.5 ENST00000381841.4	FGL1 Ensembl NCBI GeneCards UniProt Show fit	fibrinogen like 1
chr2_-_88128049 Show fit	20.17	ENST00000393750.3 ENST00000295834.8	FABP1 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 1
chr16_+_20451596 Show fit	19.93	ENST00000575690.5 ENST00000571894.1	ACSM2A Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 2A
chr16_+_20451563 Show fit	19.55	ENST00000417235.6 ENST00000219054.10	ACSM2A Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 2A
chr14_-_94293071 Show fit	19.47	ENST00000554723.5	SERPINA10 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 10
chr14_-_94293024 Show fit	19.44	ENST00000393096.5	SERPINA10 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 10
chr2_+_233729042 Show fit	19.38	ENST00000482026.6	UGT1A3 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A3
chr19_+_49513154 Show fit	18.48	ENST00000426395.7 ENST00000600273.5 ENST00000599988.5	FCGRT Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG receptor and transporter
chr7_+_45888479 Show fit	18.24	ENST00000275525.8 ENST00000468955.1	IGFBP1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 1
chr10_+_113553039 Show fit	17.88	ENST00000351270.4	HABP2 Ensembl NCBI GeneCards UniProt Show fit	hyaluronan binding protein 2
chr5_+_177086867 Show fit	17.71	ENST00000503708.5 ENST00000393648.6 ENST00000514472.1 ENST00000502906.5 ENST00000292408.9 ENST00000510911.5	FGFR4 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor receptor 4
chr14_-_94293260 Show fit	17.70	ENST00000261994.9	SERPINA10 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 10
chr6_+_31655888 Show fit	17.55	ENST00000375916.4	APOM Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein M
chr2_+_87748087 Show fit	17.20	ENST00000359481.9	PLGLB2 Ensembl NCBI GeneCards UniProt Show fit	plasminogen like B2
chr3_+_186666003 Show fit	16.73	ENST00000232003.5	HRG Ensembl NCBI GeneCards UniProt Show fit	histidine rich glycoprotein
chr4_+_3441960 Show fit	16.06	ENST00000382774.8 ENST00000511533.1	HGFAC Ensembl NCBI GeneCards UniProt Show fit	HGF activator
chr14_+_94561435 Show fit	15.69	ENST00000557004.6 ENST00000555095.5 ENST00000298841.5 ENST00000554220.5 ENST00000553780.5	SERPINA4 Ensembl NCBI GeneCards UniProt Show fit SERPINA5 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 4 serpin family A member 5
chr14_-_57493827 Show fit	15.47	ENST00000526336.1 ENST00000216445.8	CCDC198 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 198
chr6_-_25930611 Show fit	15.03	ENST00000360488.7	SLC17A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 member 2
chr19_+_11239602 Show fit	14.95	ENST00000252453.12	ANGPTL8 Ensembl NCBI GeneCards UniProt Show fit	angiopoietin like 8
chr14_+_20688756 Show fit	14.83	ENST00000397990.5 ENST00000555597.1	ANG Ensembl NCBI GeneCards UniProt Show fit RNASE4 Ensembl NCBI GeneCards UniProt Show fit	angiogenin ribonuclease A family member 4
chr17_+_42900791 Show fit	14.70	ENST00000592383.5 ENST00000253801.7 ENST00000585489.1	G6PC1 Ensembl NCBI GeneCards UniProt Show fit	glucose-6-phosphatase catalytic subunit 1
chr6_-_25930678 Show fit	14.24	ENST00000377850.8	SLC17A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 member 2
chr11_+_64555684 Show fit	14.08	ENST00000377585.7	SLC22A11 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 11
chr17_+_1742836 Show fit	13.85	ENST00000324015.7 ENST00000450523.6 ENST00000453723.5 ENST00000453066.6 ENST00000382061.5	SERPINF2 Ensembl NCBI GeneCards UniProt Show fit	serpin family F member 2
chr20_+_43558968 Show fit	13.31	ENST00000647834.1 ENST00000373100.7 ENST00000648083.1 ENST00000648530.1	SGK2 Ensembl NCBI GeneCards UniProt Show fit	serum/glucocorticoid regulated kinase 2
chr2_-_87021844 Show fit	13.26	ENST00000355705.4 ENST00000409310.6	PLGLB1 Ensembl NCBI GeneCards UniProt Show fit	plasminogen like B1
chr10_+_133527355 Show fit	13.20	ENST00000252945.8 ENST00000421586.5 ENST00000418356.1	CYP2E1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 2 subfamily E member 1
chr11_-_117824734 Show fit	13.10	ENST00000292079.7	FXYD2 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 2
chr12_-_91180365 Show fit	13.10	ENST00000547937.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr7_-_44541318 Show fit	13.07	ENST00000381160.8	NPC1L1 Ensembl NCBI GeneCards UniProt Show fit	NPC1 like intracellular cholesterol transporter 1
chr2_+_233617626 Show fit	12.83	ENST00000373450.5	UGT1A8 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A8
chr12_-_91153149 Show fit	12.60	ENST00000550758.1	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr4_-_99290975 Show fit	12.57	ENST00000209668.3	ADH1A Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 1A (class I), alpha polypeptide
chr11_+_46719193 Show fit	12.05	ENST00000311907.10 ENST00000530231.5 ENST00000442468.1	F2 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor II, thrombin
chr11_+_114296347 Show fit	11.78	ENST00000299964.4	NNMT Ensembl NCBI GeneCards UniProt Show fit	nicotinamide N-methyltransferase
chr11_+_64555924 Show fit	11.55	ENST00000301891.9	SLC22A11 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 11
chr6_-_52763473 Show fit	11.54	ENST00000493422.3	GSTA2 Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase alpha 2
chr1_+_17580474 Show fit	11.51	ENST00000375415.5	ARHGEF10L Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 10 like
chrX_-_106038721 Show fit	11.49	ENST00000372563.2	SERPINA7 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 7
chr7_-_44541262 Show fit	11.30	ENST00000289547.8 ENST00000546276.5 ENST00000423141.1	NPC1L1 Ensembl NCBI GeneCards UniProt Show fit	NPC1 like intracellular cholesterol transporter 1
chr1_+_103750406 Show fit	11.26	ENST00000370079.3	AMY1C Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 1C
chr4_-_99352754 Show fit	10.68	ENST00000639454.1	ADH1B Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 1B (class I), beta polypeptide
chr2_+_233718734 Show fit	10.49	ENST00000373409.8	UGT1A4 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A4
chr20_+_44355692 Show fit	10.12	ENST00000316673.8 ENST00000609795.5 ENST00000457232.5 ENST00000609262.5	HNF4A Ensembl NCBI GeneCards UniProt Show fit	hepatocyte nuclear factor 4 alpha
chr16_+_20764036 Show fit	10.07	ENST00000440284.6	ACSM3 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 3
chr16_-_66918839 Show fit	10.01	ENST00000565235.2 ENST00000568632.5 ENST00000565796.5	CDH16 Ensembl NCBI GeneCards UniProt Show fit	cadherin 16
chr22_-_30574572 Show fit	10.01	ENST00000402369.5	GAL3ST1 Ensembl NCBI GeneCards UniProt Show fit	galactose-3-O-sulfotransferase 1
chr16_-_66918876 Show fit	9.94	ENST00000570262.5 ENST00000299752.9 ENST00000394055.7	CDH16 Ensembl NCBI GeneCards UniProt Show fit	cadherin 16
chr8_-_69833338 Show fit	9.92	ENST00000524945.5	SLCO5A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 5A1
chr21_-_46155567 Show fit	9.89	ENST00000291670.9 ENST00000397748.5 ENST00000397743.1 ENST00000397746.8	FTCD Ensembl NCBI GeneCards UniProt Show fit	formimidoyltransferase cyclodeaminase
chr10_+_99782628 Show fit	8.56	ENST00000648689.1 ENST00000647814.1	ABCC2 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily C member 2
chr16_+_20763990 Show fit	8.33	ENST00000289416.10	ACSM3 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 3
chr20_-_7940444 Show fit	8.25	ENST00000378789.4	HAO1 Ensembl NCBI GeneCards UniProt Show fit	hydroxyacid oxidase 1
chr4_+_99574812 Show fit	8.09	ENST00000422897.6 ENST00000265517.10	MTTP Ensembl NCBI GeneCards UniProt Show fit	microsomal triglyceride transfer protein
chr10_-_50885619 Show fit	8.04	ENST00000373997.8	A1CF Ensembl NCBI GeneCards UniProt Show fit	APOBEC1 complementation factor
chr10_-_50885656 Show fit	7.91	ENST00000374001.6 ENST00000395489.6 ENST00000282641.6 ENST00000395495.5 ENST00000373995.7 ENST00000414883.1	A1CF Ensembl NCBI GeneCards UniProt Show fit	APOBEC1 complementation factor
chr2_+_233712905 Show fit	7.78	ENST00000373414.4	UGT1A5 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A5
chr6_+_25754699 Show fit	7.55	ENST00000439485.6 ENST00000377905.9	SLC17A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 member 4
chr17_-_352784 Show fit	7.47	ENST00000577079.5 ENST00000331302.12 ENST00000618002.4 ENST00000536489.6	RPH3AL Ensembl NCBI GeneCards UniProt Show fit	rabphilin 3A like (without C2 domains)
chr2_-_227379297 Show fit	7.44	ENST00000304568.4	TM4SF20 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 20
chr8_-_94208548 Show fit	7.33	ENST00000027335.8 ENST00000441892.6 ENST00000521491.1	CDH17 Ensembl NCBI GeneCards UniProt Show fit	cadherin 17
chr1_+_119368773 Show fit	7.17	ENST00000457318.5 ENST00000622548.4 ENST00000325945.4	HAO2 Ensembl NCBI GeneCards UniProt Show fit	hydroxyacid oxidase 2
chr6_+_131250375 Show fit	6.95	ENST00000474850.2	AKAP7 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 7
chr4_-_68670648 Show fit	6.92	ENST00000338206.6	UGT2B15 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B15
chr4_-_99352730 Show fit	6.75	ENST00000510055.5 ENST00000515683.6 ENST00000511397.3	ADH1C Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 1C (class I), gamma polypeptide
chr5_+_176549323 Show fit	6.70	ENST00000261944.9	CDHR2 Ensembl NCBI GeneCards UniProt Show fit	cadherin related family member 2
chr17_+_28473278 Show fit	6.65	ENST00000444914.7	SLC13A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 13 member 2
chr7_+_141995872 Show fit	6.65	ENST00000497673.5 ENST00000620571.1 ENST00000475668.6	MGAM Ensembl NCBI GeneCards UniProt Show fit	maltase-glucoamylase
chr4_-_1173168 Show fit	6.61	ENST00000514490.5 ENST00000431380.5 ENST00000503765.5	SPON2 Ensembl NCBI GeneCards UniProt Show fit	spondin 2
chr12_-_102480638 Show fit	6.38	ENST00000392904.5	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr1_-_19815270 Show fit	6.22	ENST00000375121.4	RNF186 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 186
chr1_+_62597510 Show fit	6.09	ENST00000371129.4	ANGPTL3 Ensembl NCBI GeneCards UniProt Show fit	angiopoietin like 3
chr4_-_109801978 Show fit	5.92	ENST00000510800.1 ENST00000512148.5 ENST00000394634.7 ENST00000394635.8 ENST00000645635.1	CFI Ensembl NCBI GeneCards UniProt Show fit ENSG00000285330.1 Ensembl NCBI GeneCards UniProt Show fit	complement factor I novel protein
chr21_+_38256698 Show fit	5.90	ENST00000613499.4 ENST00000612702.4 ENST00000398925.5 ENST00000398928.5 ENST00000328656.8 ENST00000443341.5	KCNJ15 Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 15
chr6_-_25874212 Show fit	5.86	ENST00000361703.10 ENST00000397060.8	SLC17A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 member 3
chr7_+_141995826 Show fit	5.81	ENST00000549489.6	MGAM Ensembl NCBI GeneCards UniProt Show fit	maltase-glucoamylase
chr15_+_48206286 Show fit	5.78	ENST00000396577.7 ENST00000380993.8	SLC12A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 1
chr9_-_91950201 Show fit	5.72	ENST00000375708.4	ROR2 Ensembl NCBI GeneCards UniProt Show fit	receptor tyrosine kinase like orphan receptor 2
chr1_+_56854764 Show fit	5.71	ENST00000361249.4	C8A Ensembl NCBI GeneCards UniProt Show fit	complement C8 alpha chain
chr20_+_44401397 Show fit	5.68	ENST00000682427.1 ENST00000681977.1 ENST00000684136.1 ENST00000684046.1 ENST00000684476.1 ENST00000619550.5 ENST00000682169.1	HNF4A Ensembl NCBI GeneCards UniProt Show fit	hepatocyte nuclear factor 4 alpha
chrX_-_15601077 Show fit	5.67	ENST00000680121.1	ACE2 Ensembl NCBI GeneCards UniProt Show fit	angiotensin I converting enzyme 2
chr13_+_33016415 Show fit	5.45	ENST00000380099.4	KL Ensembl NCBI GeneCards UniProt Show fit	klotho
chr12_-_102480604 Show fit	5.32	ENST00000392905.7	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr17_+_28473635 Show fit	5.30	ENST00000314669.10 ENST00000545060.2	SLC13A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 13 member 2
chr2_-_162074394 Show fit	5.29	ENST00000676810.1	DPP4 Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl peptidase 4
chr12_+_100473916 Show fit	5.28	ENST00000549996.5	NR1H4 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group H member 4
chr12_-_102480552 Show fit	5.26	ENST00000337514.11 ENST00000307046.8	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr12_+_100503352 Show fit	5.19	ENST00000551379.5 ENST00000188403.7	NR1H4 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group H member 4
chr19_+_1205761 Show fit	5.15	ENST00000326873.12 ENST00000586243.5	STK11 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 11
chr6_+_167291329 Show fit	5.00	ENST00000366829.2	UNC93A Ensembl NCBI GeneCards UniProt Show fit	unc-93 homolog A
chr19_+_41797147 Show fit	4.99	ENST00000596544.1	CEACAM3 Ensembl NCBI GeneCards UniProt Show fit	CEA cell adhesion molecule 3
chr21_+_38256984 Show fit	4.85	ENST00000398938.7	KCNJ15 Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 15
chr14_+_64704380 Show fit	4.84	ENST00000247226.13 ENST00000394691.7	PLEKHG3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology and RhoGEF domain containing G3
chr2_-_162074182 Show fit	4.71	ENST00000360534.8	DPP4 Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl peptidase 4
chr16_+_89630263 Show fit	4.66	ENST00000261615.5	DPEP1 Ensembl NCBI GeneCards UniProt Show fit	dipeptidase 1
chrX_-_15600953 Show fit	4.66	ENST00000679212.1 ENST00000679278.1 ENST00000678046.1 ENST00000252519.8	ACE2 Ensembl NCBI GeneCards UniProt Show fit	angiotensin I converting enzyme 2
chr2_-_162074050 Show fit	4.62	ENST00000676768.1	DPP4 Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl peptidase 4
chr8_-_86743626 Show fit	4.56	ENST00000320005.6	CNGB3 Ensembl NCBI GeneCards UniProt Show fit	cyclic nucleotide gated channel subunit beta 3
chr7_-_27180230 Show fit	4.55	ENST00000396344.4	HOXA10 Ensembl NCBI GeneCards UniProt Show fit	homeobox A10
chr12_+_100473951 Show fit	4.35	ENST00000648861.1 ENST00000546380.1	NR1H4 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group H member 4
chr14_-_64942720 Show fit	4.27	ENST00000557049.1 ENST00000389614.6	GPX2 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 2
chr3_-_138174879 Show fit	4.24	ENST00000260803.9	DBR1 Ensembl NCBI GeneCards UniProt Show fit	debranching RNA lariats 1
chr6_-_116060859 Show fit	4.17	ENST00000606080.2	FRK Ensembl NCBI GeneCards UniProt Show fit	fyn related Src family tyrosine kinase
chr22_+_44702186 Show fit	4.14	ENST00000336985.11 ENST00000403696.5 ENST00000457960.5 ENST00000361473.9	PRR5 Ensembl NCBI GeneCards UniProt Show fit PRR5-ARHGAP8 Ensembl NCBI GeneCards UniProt Show fit	proline rich 5 PRR5-ARHGAP8 readthrough
chr4_+_186266183 Show fit	4.11	ENST00000403665.7 ENST00000492972.6 ENST00000264692.8	F11 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor XI
chr2_+_27496830 Show fit	4.09	ENST00000264717.7	GCKR Ensembl NCBI GeneCards UniProt Show fit	glucokinase regulator
chr6_+_31739948 Show fit	4.05	ENST00000375755.8 ENST00000425703.5 ENST00000375750.9 ENST00000375703.7 ENST00000375740.7	MSH5 Ensembl NCBI GeneCards UniProt Show fit	mutS homolog 5
chr12_+_21131187 Show fit	3.96	ENST00000256958.3	SLCO1B1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 1B1
chr14_-_64942783 Show fit	3.92	ENST00000612794.1	GPX2 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 2
chr14_+_39233908 Show fit	3.91	ENST00000280082.4	MIA2 Ensembl NCBI GeneCards UniProt Show fit	MIA SH3 domain ER export factor 2
chr8_+_22053543 Show fit	3.86	ENST00000519850.5 ENST00000381470.7	DMTN Ensembl NCBI GeneCards UniProt Show fit	dematin actin binding protein
chrX_+_16650155 Show fit	3.84	ENST00000380200.3	S100G Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein G
chr1_+_103617427 Show fit	3.83	ENST00000423678.2 ENST00000414303.7	AMY2A Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 2A
chr17_+_70075317 Show fit	3.75	ENST00000589377.1	KCNJ16 Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 16
chr7_-_150323489 Show fit	3.75	ENST00000683684.1 ENST00000478393.5	ACTR3C Ensembl NCBI GeneCards UniProt Show fit	actin related protein 3C
chr12_-_110920568 Show fit	3.71	ENST00000548438.1 ENST00000228841.15	MYL2 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 2
chr8_-_123737378 Show fit	3.60	ENST00000419625.6 ENST00000262219.10	ANXA13 Ensembl NCBI GeneCards UniProt Show fit	annexin A13
chr12_-_18090141 Show fit	3.60	ENST00000536890.1	RERGL Ensembl NCBI GeneCards UniProt Show fit	RERG like
chr22_-_21982748 Show fit	3.57	ENST00000398793.6 ENST00000437929.5 ENST00000456075.5 ENST00000434517.1 ENST00000424393.5 ENST00000357179.10 ENST00000449704.5 ENST00000437103.1	TOP3B Ensembl NCBI GeneCards UniProt Show fit	DNA topoisomerase III beta
chr6_+_125749623 Show fit	3.50	ENST00000368364.4	HEY2 Ensembl NCBI GeneCards UniProt Show fit	hes related family bHLH transcription factor with YRPW motif 2
chr19_+_41796616 Show fit	3.43	ENST00000344550.4	CEACAM3 Ensembl NCBI GeneCards UniProt Show fit	CEA cell adhesion molecule 3
chr13_-_103066411 Show fit	3.43	ENST00000245312.5	SLC10A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 10 member 2
chr22_+_30607072 Show fit	3.41	ENST00000450638.5	TCN2 Ensembl NCBI GeneCards UniProt Show fit	transcobalamin 2
chr12_+_100473708 Show fit	3.41	ENST00000548884.5 ENST00000392986.8	NR1H4 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group H member 4
chr19_+_41796580 Show fit	3.40	ENST00000357396.8 ENST00000630848.2	CEACAM3 Ensembl NCBI GeneCards UniProt Show fit	CEA cell adhesion molecule 3
chr6_-_29045175 Show fit	3.37	ENST00000377175.2	OR2W1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily W member 1
chr10_-_70888546 Show fit	3.31	ENST00000299299.4	PCBD1 Ensembl NCBI GeneCards UniProt Show fit	pterin-4 alpha-carbinolamine dehydratase 1
chr22_+_30607145 Show fit	3.24	ENST00000405742.7	TCN2 Ensembl NCBI GeneCards UniProt Show fit	transcobalamin 2
chr13_+_95433593 Show fit	3.23	ENST00000376873.7	CLDN10 Ensembl NCBI GeneCards UniProt Show fit	claudin 10
chr22_+_30607167 Show fit	3.21	ENST00000215838.8	TCN2 Ensembl NCBI GeneCards UniProt Show fit	transcobalamin 2
chr17_+_70075215 Show fit	3.20	ENST00000283936.5 ENST00000615244.4 ENST00000392671.6	KCNJ16 Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 16
chr2_-_74328166 Show fit	3.18	ENST00000358683.8	SLC4A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 member 5
chr15_+_58138368 Show fit	3.16	ENST00000219919.9 ENST00000536493.1	AQP9 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr9_+_100099233 Show fit	3.08	ENST00000262457.7 ENST00000262456.6 ENST00000374921.3	INVS Ensembl NCBI GeneCards UniProt Show fit	inversin
chr7_+_130486171 Show fit	2.97	ENST00000341441.9 ENST00000416162.7	MEST Ensembl NCBI GeneCards UniProt Show fit	mesoderm specific transcript
chr1_-_207032749 Show fit	2.88	ENST00000359470.6 ENST00000461135.2	C1orf116 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 116
chr12_-_18090185 Show fit	2.73	ENST00000229002.6 ENST00000538724.6	RERGL Ensembl NCBI GeneCards UniProt Show fit	RERG like
chr4_-_69653223 Show fit	2.72	ENST00000286604.8 ENST00000505512.1 ENST00000514019.1	UGT2A1 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member A1 complex locus
chr7_+_130486324 Show fit	2.69	ENST00000427521.6 ENST00000378576.9	MEST Ensembl NCBI GeneCards UniProt Show fit	mesoderm specific transcript
chr12_+_18242955 Show fit	2.65	ENST00000676171.1	PIK3C2G Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr6_+_167291309 Show fit	2.64	ENST00000230256.8	UNC93A Ensembl NCBI GeneCards UniProt Show fit	unc-93 homolog A
chr5_+_132369691 Show fit	2.60	ENST00000245407.8	SLC22A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 5
chr1_+_207088825 Show fit	2.56	ENST00000367078.8	C4BPB Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr14_+_24120956 Show fit	2.53	ENST00000558325.2	ENSG00000259371.2 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr1_+_207089283 Show fit	2.50	ENST00000391923.1	C4BPB Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr6_-_117425905 Show fit	2.49	ENST00000368507.8	ROS1 Ensembl NCBI GeneCards UniProt Show fit	ROS proto-oncogene 1, receptor tyrosine kinase
chr6_+_106086316 Show fit	2.49	ENST00000369091.6 ENST00000369096.9	PRDM1 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 1
chr6_-_117425855 Show fit	2.38	ENST00000368508.7	ROS1 Ensembl NCBI GeneCards UniProt Show fit	ROS proto-oncogene 1, receptor tyrosine kinase
chr16_-_87936529 Show fit	2.36	ENST00000649794.3 ENST00000649158.1 ENST00000648177.1	CA5A Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 5A
chr19_-_41627051 Show fit	2.25	ENST00000221954.6 ENST00000600925.1	CEACAM4 Ensembl NCBI GeneCards UniProt Show fit	CEA cell adhesion molecule 4
chr4_+_119135825 Show fit	2.19	ENST00000307128.6	MYOZ2 Ensembl NCBI GeneCards UniProt Show fit	myozenin 2
chr4_+_168092530 Show fit	2.09	ENST00000359299.8	ANXA10 Ensembl NCBI GeneCards UniProt Show fit	annexin A10
chr12_+_25052732 Show fit	2.08	ENST00000547044.5	IRAG2 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr6_+_167122742 Show fit	1.97	ENST00000341935.9 ENST00000349984.6	CCR6 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine receptor 6
chr7_-_123199960 Show fit	1.89	ENST00000194130.7	SLC13A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 13 member 1
chr1_+_207089233 Show fit	1.87	ENST00000243611.9 ENST00000367076.7	C4BPB Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr15_-_55408018 Show fit	1.84	ENST00000569205.5	CCPG1 Ensembl NCBI GeneCards UniProt Show fit	cell cycle progression 1
chr12_-_8540873 Show fit	1.77	ENST00000545274.5 ENST00000446457.6 ENST00000299663.8	CLEC4E Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 4 member E
chr11_+_560956 Show fit	1.68	ENST00000397582.7 ENST00000397583.8	RASSF7 Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 7
chr3_+_38265802 Show fit	1.65	ENST00000311856.9	SLC22A13 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 13
chr12_+_20810698 Show fit	1.58	ENST00000540853.5 ENST00000381545.8	SLCO1B3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 1B3
chr10_-_37857582 Show fit	1.47	ENST00000395867.8 ENST00000611278.4	ZNF248 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 248
chr5_-_35195236 Show fit	1.35	ENST00000509839.5	PRLR Ensembl NCBI GeneCards UniProt Show fit	prolactin receptor
chr15_+_85380565 Show fit	1.34	ENST00000559362.5 ENST00000394518.7	AKAP13 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 13
chrX_+_1591590 Show fit	1.31	ENST00000313871.9 ENST00000381261.8	AKAP17A Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 17A
chr8_-_107498041 Show fit	1.25	ENST00000297450.7	ANGPT1 Ensembl NCBI GeneCards UniProt Show fit	angiopoietin 1
chr4_-_993430 Show fit	1.24	ENST00000361661.6 ENST00000622731.4	SLC26A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 1
chr22_+_32043253 Show fit	1.20	ENST00000266088.9	SLC5A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 5 member 1
chr20_+_44401222 Show fit	1.12	ENST00000316099.9	HNF4A Ensembl NCBI GeneCards UniProt Show fit	hepatocyte nuclear factor 4 alpha
chr1_-_197067234 Show fit	1.09	ENST00000367412.2	F13B Ensembl NCBI GeneCards UniProt Show fit	coagulation factor XIII B chain
chr7_-_115968302 Show fit	1.05	ENST00000457268.5	TFEC Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chr10_-_99930893 Show fit	1.05	ENST00000636706.1	DNMBP Ensembl NCBI GeneCards UniProt Show fit	dynamin binding protein
chr11_-_83682385 Show fit	1.04	ENST00000426717.6	DLG2 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 2
chr8_-_107497909 Show fit	0.98	ENST00000517746.6	ANGPT1 Ensembl NCBI GeneCards UniProt Show fit	angiopoietin 1
chr3_-_192727500 Show fit	0.97	ENST00000430714.5 ENST00000418610.1 ENST00000445105.7 ENST00000684728.1 ENST00000448795.5 ENST00000683935.1 ENST00000684282.1 ENST00000683451.1	FGF12 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor 12
chr1_-_113887574 Show fit	0.92	ENST00000393316.8	BCL2L15 Ensembl NCBI GeneCards UniProt Show fit	BCL2 like 15
chr11_-_83682414 Show fit	0.91	ENST00000404783.7	DLG2 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.6	145.8	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
13.5	40.5	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
12.3	36.9	GO:0010133	proline catabolic process to glutamate(GO:0010133)
11.1	33.2	GO:0019836	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
9.6	115.5	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
9.4	56.6	GO:0008218	bioluminescence(GO:0008218)
9.3	27.9	GO:0042427	serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314)
7.3	80.8	GO:0043152	induction of bacterial agglutination(GO:0043152)
7.1	28.5	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
6.0	60.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
5.6	100.8	GO:0001542	ovulation from ovarian follicle(GO:0001542)
4.6	18.2	GO:0090293	nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
4.4	13.2	GO:0016999	antibiotic metabolic process(GO:0016999)
4.4	17.5	GO:0034444	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
4.1	33.1	GO:0015747	urate transport(GO:0015747)
4.0	8.1	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
3.7	29.3	GO:0045959	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
3.5	17.7	GO:1903412	response to bile acid(GO:1903412)
3.4	10.3	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
3.4	17.0	GO:1904073	regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
3.3	9.9	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
3.1	15.7	GO:0061107	seminal vesicle development(GO:0061107)
3.1	12.5	GO:0000023	maltose metabolic process(GO:0000023)
2.7	8.2	GO:0009441	glycolate metabolic process(GO:0009441)
2.7	16.0	GO:0016554	cytidine to uridine editing(GO:0016554)
2.6	13.2	GO:0010193	response to ozone(GO:0010193)
2.6	23.4	GO:0055091	phospholipid homeostasis(GO:0055091)
2.5	30.0	GO:0006069	ethanol oxidation(GO:0006069)
2.5	14.8	GO:0006651	diacylglycerol biosynthetic process(GO:0006651) activation of phospholipase A2 activity(GO:0032431)
2.4	7.3	GO:0002314	germinal center B cell differentiation(GO:0002314)
2.2	6.7	GO:0090675	intermicrovillar adhesion(GO:0090675)
2.1	25.7	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
2.1	48.9	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
2.1	14.6	GO:0036343	psychomotor behavior(GO:0036343)
2.0	59.2	GO:0042359	vitamin D metabolic process(GO:0042359)
1.8	20.2	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
1.8	36.8	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
1.4	5.7	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.4	4.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
1.4	24.4	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
1.3	15.5	GO:0070327	thyroid hormone transport(GO:0070327)
1.2	4.9	GO:0010966	regulation of phosphate transport(GO:0010966)
1.2	38.9	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
1.2	3.5	GO:2000722	regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722)
1.2	15.0	GO:0050746	regulation of lipoprotein metabolic process(GO:0050746)
1.1	10.0	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.1	3.2	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
1.1	3.2	GO:0015722	canalicular bile acid transport(GO:0015722)
1.0	3.9	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.9	9.5	GO:0052695	cellular glucuronidation(GO:0052695)
0.9	4.5	GO:0044245	polysaccharide digestion(GO:0044245)
0.9	13.1	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.9	5.2	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.8	2.5	GO:1990654	regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.8	9.9	GO:0006824	cobalt ion transport(GO:0006824)
0.7	2.2	GO:0035691	macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.7	11.8	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.7	4.1	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.7	2.0	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.6	3.9	GO:1901731	positive regulation of platelet aggregation(GO:1901731)
0.6	31.9	GO:0051180	vitamin transport(GO:0051180)
0.5	11.5	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.5	2.6	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.5	3.6	GO:1902358	sulfate transmembrane transport(GO:1902358)
0.5	34.7	GO:0006953	acute-phase response(GO:0006953)
0.5	4.1	GO:0051026	chiasma assembly(GO:0051026)
0.4	3.3	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.4	14.9	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4	11.5	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.4	15.4	GO:0010107	potassium ion import(GO:0010107)
0.4	5.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.3	3.7	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.3	45.8	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.3	1.3	GO:0038161	prolactin signaling pathway(GO:0038161)
0.3	1.3	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3	4.1	GO:0038203	TORC2 signaling(GO:0038203)
0.3	3.6	GO:0006265	DNA topological change(GO:0006265)
0.2	3.4	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.2	1.8	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2	4.6	GO:0060065	uterus development(GO:0060065)
0.2	1.2	GO:0001951	intestinal D-glucose absorption(GO:0001951)
0.2	6.9	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.2	1.0	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.1	0.4	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1	3.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	9.8	GO:0006835	dicarboxylic acid transport(GO:0006835)
0.1	8.2	GO:1990748	cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1	17.4	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.1	2.6	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1	7.2	GO:0009062	fatty acid catabolic process(GO:0009062)
0.1	5.6	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.1	0.4	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.1	1.9	GO:0097120	receptor localization to synapse(GO:0097120)
0.1	4.2	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	5.8	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	2.4	GO:0015701	bicarbonate transport(GO:0015701)
0.0	5.9	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	4.2	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	1.7	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	3.5	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	5.2	GO:0007498	mesoderm development(GO:0007498)
0.0	1.8	GO:0002292	T cell differentiation involved in immune response(GO:0002292)
0.0	0.3	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	2.2	GO:0030239	myofibril assembly(GO:0030239)
0.0	11.1	GO:0006979	response to oxidative stress(GO:0006979)
0.0	11.8	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	7.4	GO:0045861	negative regulation of proteolysis(GO:0045861)
0.0	3.1	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.0	108.5	GO:0005577	fibrinogen complex(GO:0005577)
6.9	41.5	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
5.2	15.7	GO:0036027	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
4.4	17.5	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
4.3	34.2	GO:0005579	membrane attack complex(GO:0005579)
4.0	16.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
3.2	61.7	GO:0031089	platelet dense granule lumen(GO:0031089)
2.5	20.2	GO:0045179	apical cortex(GO:0045179)
2.5	14.8	GO:0032311	angiogenin-PRI complex(GO:0032311)
2.3	23.2	GO:0046581	intercellular canaliculus(GO:0046581)
2.2	33.0	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
2.1	17.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
2.0	25.7	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.2	9.9	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.1	6.7	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.0	5.2	GO:0036398	TCR signalosome(GO:0036398)
0.9	313.6	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.7	13.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.7	131.2	GO:0072562	blood microparticle(GO:0072562)
0.5	18.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.5	34.0	GO:0031526	brush border membrane(GO:0031526)
0.4	20.7	GO:0034358	plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.3	4.7	GO:0031528	microvillus membrane(GO:0031528)
0.3	15.4	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2	3.7	GO:0097512	cardiac myofibril(GO:0097512)
0.2	2.0	GO:0097524	sperm plasma membrane(GO:0097524)
0.2	4.1	GO:0031932	TORC2 complex(GO:0031932)
0.2	4.1	GO:0032300	mismatch repair complex(GO:0032300)
0.2	3.5	GO:0016580	Sin3 complex(GO:0016580)
0.2	90.9	GO:0005759	mitochondrial matrix(GO:0005759)
0.2	3.9	GO:0031095	spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095)
0.1	27.9	GO:0008021	synaptic vesicle(GO:0008021)
0.1	56.8	GO:0016324	apical plasma membrane(GO:0016324)
0.1	7.3	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	11.8	GO:0035579	specific granule membrane(GO:0035579)
0.1	25.2	GO:0030133	transport vesicle(GO:0030133)
0.1	37.2	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.1	2.0	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	3.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1	9.9	GO:0043202	lysosomal lumen(GO:0043202)
0.1	13.2	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1	1.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	6.9	GO:0044215	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	8.9	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1	59.4	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.1	4.2	GO:0035580	specific granule lumen(GO:0035580)
0.1	4.6	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	2.2	GO:0005902	microvillus(GO:0005902)
0.0	6.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	52.8	GO:0005615	extracellular space(GO:0005615)
0.0	1.3	GO:0031904	endosome lumen(GO:0031904)
0.0	3.2	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	40.6	GO:0005887	integral component of plasma membrane(GO:0005887)
0.0	4.9	GO:0009986	cell surface(GO:0009986)
0.0	2.2	GO:0030018	Z disc(GO:0030018)
0.0	0.9	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	1.0	GO:0005795	Golgi stack(GO:0005795)
0.0	1.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
20.1	60.2	GO:1902271	D3 vitamins binding(GO:1902271)
15.4	61.7	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
10.6	31.9	GO:0008431	vitamin E binding(GO:0008431)
10.6	105.8	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
10.1	40.5	GO:0019770	IgG receptor activity(GO:0019770)
5.2	41.5	GO:1990405	protein antigen binding(GO:1990405)
5.1	15.4	GO:0052853	(S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
4.6	18.2	GO:0038181	bile acid receptor activity(GO:0038181) chenodeoxycholic acid binding(GO:1902122)
4.2	12.5	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
4.0	11.9	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
3.7	30.0	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
3.5	38.9	GO:0031995	insulin-like growth factor II binding(GO:0031995)
3.5	31.5	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
3.4	130.3	GO:0001972	retinoic acid binding(GO:0001972)
3.1	36.8	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
3.0	14.8	GO:0004522	ribonuclease A activity(GO:0004522)
2.9	20.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
2.3	9.3	GO:0005499	vitamin D binding(GO:0005499)
2.2	33.2	GO:0015643	toxic substance binding(GO:0015643)
2.1	10.3	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
2.0	9.9	GO:0016841	ammonia-lyase activity(GO:0016841)
1.9	5.8	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
1.9	48.9	GO:0034185	apolipoprotein binding(GO:0034185)
1.6	4.7	GO:0070573	metallodipeptidase activity(GO:0070573)
1.5	17.7	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
1.5	7.3	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
1.3	134.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
1.3	3.8	GO:0004556	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
1.3	36.9	GO:0071949	FAD binding(GO:0071949)
1.3	10.0	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
1.2	3.6	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
1.1	3.2	GO:0015265	urea channel activity(GO:0015265)
1.0	4.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
1.0	13.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
1.0	12.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.9	24.4	GO:0031489	myosin V binding(GO:0031489)
0.9	17.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.9	2.6	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.9	3.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.8	7.5	GO:0030274	LIM domain binding(GO:0030274)
0.8	3.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.8	5.7	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.8	4.6	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.8	9.9	GO:0031419	cobalamin binding(GO:0031419)
0.7	13.2	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.7	17.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.7	8.6	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.6	13.3	GO:0017081	chloride channel regulator activity(GO:0017081)
0.6	14.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.6	28.5	GO:0008009	chemokine activity(GO:0008009)
0.5	10.3	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.5	27.9	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.4	3.6	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.4	2.2	GO:0051373	FATZ binding(GO:0051373)
0.3	11.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.3	39.3	GO:0051087	chaperone binding(GO:0051087)
0.3	1.3	GO:0004925	prolactin receptor activity(GO:0004925)
0.3	20.3	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.3	25.7	GO:0050840	extracellular matrix binding(GO:0050840)
0.3	17.5	GO:0016209	antioxidant activity(GO:0016209)
0.3	2.6	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3	8.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	0.7	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.2	6.6	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.2	6.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.2	6.9	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.2	5.2	GO:0030275	LRR domain binding(GO:0030275)
0.2	4.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.2	3.7	GO:0032036	myosin heavy chain binding(GO:0032036)
0.2	4.7	GO:0001848	complement binding(GO:0001848)
0.2	3.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.2	18.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2	4.1	GO:0030983	mismatched DNA binding(GO:0030983)
0.2	40.3	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	4.2	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.2	20.2	GO:0005179	hormone activity(GO:0005179)
0.1	0.4	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	2.0	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	2.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	16.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	8.1	GO:0005548	phospholipid transporter activity(GO:0005548)
0.1	5.7	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	11.8	GO:0008170	N-methyltransferase activity(GO:0008170)
0.1	2.5	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	3.9	GO:0030507	spectrin binding(GO:0030507)
0.1	15.7	GO:0030674	protein binding, bridging(GO:0030674)
0.1	4.9	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1	4.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	1.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	3.5	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	4.6	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.1	GO:0004991	parathyroid hormone receptor activity(GO:0004991)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	202.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
2.0	115.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.7	190.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5	25.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.4	10.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.3	18.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.3	20.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	3.7	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	17.0	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.2	6.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	4.6	PID CONE PATHWAY	Visual signal transduction: Cones
0.2	5.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.2	12.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	4.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	6.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	8.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	19.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	6.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.1	5.2	PID LKB1 PATHWAY	LKB1 signaling events
0.1	4.1	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	2.6	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	5.1	PID FGF PATHWAY	FGF signaling pathway
0.0	7.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	1.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	8.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	1.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.9	87.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
4.7	118.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
3.4	80.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
3.0	30.0	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
2.6	42.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
2.4	28.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
1.7	60.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
1.6	36.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
1.6	68.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
1.6	28.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
1.4	27.9	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
1.3	20.7	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
1.0	17.7	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
1.0	25.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.9	14.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.7	13.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.7	50.7	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.6	17.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.5	17.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4	14.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3	49.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	4.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.2	3.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.2	13.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	8.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.2	10.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.2	3.9	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.2	5.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.2	2.0	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	2.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	2.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	20.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	4.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	2.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	4.1	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	3.2	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	19.3	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.1	16.0	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.1	10.6	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	3.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	3.4	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	5.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.4	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds

Results for HNF1A_HNF1B

Z-value: 2.08

Motif logo

Transcription factors associated with HNF1A_HNF1B

Activity-expression correlation:

Activity profile of HNF1A_HNF1B motif

Sorted Z-values of HNF1A_HNF1B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF1A_HNF1B

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: