Project
GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for HNF4G
Z-value: 1.16
Motif logo
Transcription factors associated with HNF4G
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HNF4G | hg38_v1_chr8_+_75539862_75539892, hg38_v1_chr8_+_75539893_75539968 | -0.29 | 1.7e-05 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HNF4G
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.1 | 40.5 | GO:0009440 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 2.3 | 38.7 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 4.0 | 36.0 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 2.6 | 34.0 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.2 | 30.7 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.7 | 24.8 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 1.1 | 21.7 | GO:0031441 | negative regulation of mRNA 3'-end processing(GO:0031441) |
| 1.0 | 20.0 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.3 | 20.0 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 3.2 | 19.2 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 129.1 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.5 | 53.7 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.6 | 45.8 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 31.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.5 | 31.3 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.2 | 31.1 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 29.9 | GO:0005730 | nucleolus(GO:0005730) |
| 0.1 | 27.1 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 1.5 | 24.0 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 2.7 | 21.8 | GO:0016012 | sarcoglycan complex(GO:0016012) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 43.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 1.0 | 43.4 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.4 | 34.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 11.3 | 34.0 | GO:0003978 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 0.2 | 30.6 | GO:0005178 | integrin binding(GO:0005178) |
| 9.6 | 28.8 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 1.5 | 24.0 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.1 | 23.9 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.0 | 20.4 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 2.2 | 20.0 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 59.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.3 | 29.6 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.2 | 17.7 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 13.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.4 | 13.6 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 12.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.2 | 11.5 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 11.1 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.2 | 10.9 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.4 | 9.7 | PID ARF 3PATHWAY | Arf1 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 45.2 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 2.4 | 43.8 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.7 | 41.0 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 1.4 | 37.9 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 36.5 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.5 | 19.8 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.5 | 19.8 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 19.8 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |
| 0.9 | 19.7 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.9 | 18.1 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |