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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXA13

Z-value: 0.73

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Transcription factors associated with HOXA13

Gene Symbol Gene ID Gene Info
ENSG00000106031.9 HOXA13

Activity profile of HOXA13 motif

Sorted Z-values of HOXA13 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA13

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_121435595 14.96 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr3_-_195583931 14.34 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr2_+_188974364 13.00 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr5_-_151686908 10.54 ENST00000231061.9
secreted protein acidic and cysteine rich
chr3_-_123620571 9.50 ENST00000583087.5
myosin light chain kinase
chr5_-_79991237 9.40 ENST00000512560.5
ENST00000509852.6
ENST00000512528.3
ENST00000617335.4
metaxin 3
chr3_-_123620496 8.69 ENST00000578202.1
myosin light chain kinase
chr12_-_12338674 8.40 ENST00000545735.1
MANSC domain containing 1
chr12_-_91153149 8.12 ENST00000550758.1
decorin
chr8_-_126557691 7.38 ENST00000652209.1
LRAT domain containing 2
chr10_+_104269163 7.27 ENST00000338595.7
glutathione S-transferase omega 2
chr2_-_86105839 7.13 ENST00000263857.11
RNA polymerase I subunit A
chr19_+_16888991 6.85 ENST00000248076.4
F2R like thrombin or trypsin receptor 3
chr6_+_150721073 6.33 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr6_-_11807045 6.28 ENST00000379415.6
androgen dependent TFPI regulating protein
chr3_+_101827982 6.27 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr12_+_12725897 5.96 ENST00000326765.10
apolipoprotein L domain containing 1
chr4_+_105710809 5.87 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
glutathione S-transferase C-terminal domain containing
chr18_-_55587335 5.84 ENST00000638154.3
transcription factor 4
chr8_+_132866948 5.83 ENST00000220616.9
thyroglobulin
chr11_-_22829793 5.76 ENST00000354193.5
small VCP interacting protein
chr12_-_70788914 5.64 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr9_-_86947496 5.30 ENST00000298743.9
growth arrest specific 1
chr18_-_55588535 5.27 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
transcription factor 4
chr5_-_19988179 5.20 ENST00000502796.5
ENST00000382275.6
ENST00000511273.1
cadherin 18
chr5_-_138875290 5.05 ENST00000521094.2
ENST00000274711.7
leucine rich repeat transmembrane neuronal 2
chr1_+_50109817 5.05 ENST00000652353.1
ENST00000371821.6
ENST00000652274.1
ELAV like RNA binding protein 4
chr13_-_35855758 4.94 ENST00000615680.4
doublecortin like kinase 1
chr5_+_36608146 4.81 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr9_+_706841 4.55 ENST00000382293.7
KN motif and ankyrin repeat domains 1
chr20_-_54070520 4.46 ENST00000371435.6
ENST00000395961.7
brain enriched myelin associated protein 1
chr4_+_20251896 4.34 ENST00000504154.6
slit guidance ligand 2
chr1_+_50109620 4.14 ENST00000371819.1
ELAV like RNA binding protein 4
chr19_-_9107475 4.14 ENST00000641081.1
olfactory receptor family 7 subfamily G member 2
chr10_-_77637789 4.12 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr17_-_41865403 4.11 ENST00000319121.4
kelch like family member 11
chr5_+_141350081 4.10 ENST00000523390.2
ENST00000611598.1
protocadherin gamma subfamily B, 1
chr13_-_35855627 4.08 ENST00000379893.5
doublecortin like kinase 1
chr10_-_77637902 3.98 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr10_-_67838173 3.95 ENST00000225171.7
DnaJ heat shock protein family (Hsp40) member C12
chr12_+_26121984 3.95 ENST00000538142.5
sarcospan
chr3_+_4493442 3.89 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
inositol 1,4,5-trisphosphate receptor type 1
chr1_+_15236509 3.86 ENST00000683790.1
forkhead associated phosphopeptide binding domain 1
chr18_-_5544250 3.80 ENST00000540638.6
ENST00000342933.7
erythrocyte membrane protein band 4.1 like 3
chr16_-_21278282 3.76 ENST00000572914.2
crystallin mu
chr3_+_155083889 3.75 ENST00000680282.1
membrane metalloendopeptidase
chr11_-_114595750 3.71 ENST00000424261.6
neurexophilin and PC-esterase domain family member 4
chr3_+_155083523 3.70 ENST00000680057.1
membrane metalloendopeptidase
chr1_+_50109788 3.69 ENST00000651258.1
ELAV like RNA binding protein 4
chr11_-_114595777 3.65 ENST00000375478.4
neurexophilin and PC-esterase domain family member 4
chr18_-_55588184 3.61 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr11_+_62123991 3.60 ENST00000533896.5
ENST00000278849.4
ENST00000394818.8
inner centromere protein
chr1_+_50105666 3.59 ENST00000651347.1
ELAV like RNA binding protein 4
chr14_+_100019375 3.52 ENST00000544450.6
Enah/Vasp-like
chr6_+_131573219 3.50 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr14_-_91947654 3.47 ENST00000342058.9
fibulin 5
chr3_+_4493340 3.38 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
inositol 1,4,5-trisphosphate receptor type 1
chr12_+_119667859 3.37 ENST00000541640.5
protein kinase AMP-activated non-catalytic subunit beta 1
chr3_-_161105399 3.36 ENST00000652593.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_42463221 3.35 ENST00000654683.1
ENST00000667205.1
ENST00000655164.1
ENST00000657597.1
ENST00000667947.1
ENST00000668663.1
ENST00000660083.1
ENST00000655845.1
ENST00000671281.1
ENST00000664805.1
ENST00000654604.1
ENST00000655447.1
ENST00000661864.1
ENST00000665176.1
ENST00000670982.1
ENST00000668036.1
coiled-coil domain containing 30
chr3_-_161105224 3.34 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr5_+_174045673 3.32 ENST00000303177.8
ENST00000519867.5
neuronal vesicle trafficking associated 2
chr19_-_1592794 3.30 ENST00000156825.5
methyl-CpG binding domain protein 3
chr6_+_147508645 3.28 ENST00000367474.2
sterile alpha motif domain containing 5
chr16_+_81314922 3.27 ENST00000648994.2
gigaxonin
chr1_+_43300971 3.25 ENST00000372476.8
ENST00000538015.1
tyrosine kinase with immunoglobulin like and EGF like domains 1
chr5_-_118988504 3.18 ENST00000515439.7
ENST00000510708.6
DTW domain containing 2
chr4_+_94757921 3.17 ENST00000515059.6
bone morphogenetic protein receptor type 1B
chr19_+_16719841 3.16 ENST00000524140.7
NACHT and WD repeat domain containing 1
chr2_+_33436304 3.16 ENST00000402538.7
RAS guanyl releasing protein 3
chr8_-_85378105 3.10 ENST00000521846.5
ENST00000523022.6
ENST00000524324.5
ENST00000519991.5
ENST00000520663.5
ENST00000517590.5
ENST00000522579.5
ENST00000522814.5
ENST00000522662.5
ENST00000523858.5
ENST00000519129.5
carbonic anhydrase 1
chr1_+_13583762 3.05 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chr19_-_1592829 3.04 ENST00000434436.8
methyl-CpG binding domain protein 3
chr2_-_166128004 3.02 ENST00000303395.9
ENST00000674923.1
ENST00000637988.1
ENST00000635776.1
sodium voltage-gated channel alpha subunit 1
chr19_+_16720004 2.98 ENST00000673803.1
ENST00000549814.5
NACHT and WD repeat domain containing 1
chr3_-_161105070 2.94 ENST00000651430.1
ENST00000650695.1
ENST00000651689.1
ENST00000651916.1
ENST00000488170.5
ENST00000652377.1
ENST00000652669.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_-_25430147 2.83 ENST00000349320.7
Rh blood group CcEe antigens
chr8_-_33567118 2.83 ENST00000256257.2
ring finger protein 122
chr4_-_1208825 2.82 ENST00000511679.5
ENST00000617421.4
spondin 2
chr3_-_99850976 2.79 ENST00000487087.5
filamin A interacting protein 1 like
chrX_+_49922559 2.75 ENST00000376091.8
chloride voltage-gated channel 5
chr19_-_18522051 2.75 ENST00000262809.9
elongation factor for RNA polymerase II
chr3_-_114758940 2.70 ENST00000464560.5
zinc finger and BTB domain containing 20
chr6_+_109095481 2.67 ENST00000521522.5
ENST00000524064.5
ENST00000522608.5
ENST00000517392.6
ENST00000521503.5
ENST00000519407.5
ENST00000519095.5
ENST00000368968.6
ENST00000522490.5
ENST00000523209.5
ENST00000368970.6
ENST00000520883.5
ENST00000523787.5
centrosomal protein 57 like 1
chr12_-_52680398 2.66 ENST00000252244.3
keratin 1
chr19_-_40404270 2.65 ENST00000673881.1
periaxin
chr6_+_72366730 2.63 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr11_+_101914997 2.59 ENST00000263468.13
centrosomal protein 126
chr1_+_50106265 2.58 ENST00000357083.8
ELAV like RNA binding protein 4
chr3_+_98147479 2.57 ENST00000641380.1
olfactory receptor family 5 subfamily H member 14
chr19_+_19211949 2.56 ENST00000252575.11
neurocan
chr1_+_173824626 2.55 ENST00000648960.1
ENST00000648807.1
ENST00000649067.1
ENST00000649689.2
aspartyl-tRNA synthetase 2, mitochondrial
chr1_+_173824694 2.48 ENST00000647645.1
aspartyl-tRNA synthetase 2, mitochondrial
chr8_-_94262308 2.46 ENST00000297596.3
ENST00000396194.6
GTP binding protein overexpressed in skeletal muscle
chr7_+_87934143 2.46 ENST00000398204.8
ADAM metallopeptidase domain 22
chr10_-_49762335 2.43 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr15_-_58279245 2.38 ENST00000558231.5
aldehyde dehydrogenase 1 family member A2
chr2_-_151971750 2.38 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chr6_+_44342639 2.36 ENST00000674044.1
ENST00000515220.5
ENST00000323108.12
spermatogenesis associated serine rich 1
chr8_-_9150648 2.34 ENST00000310455.4
protein phosphatase 1 regulatory subunit 3B
chr2_-_2324642 2.33 ENST00000650485.1
ENST00000649207.1
myelin transcription factor 1 like
chr5_+_68288346 2.32 ENST00000320694.12
phosphoinositide-3-kinase regulatory subunit 1
chr10_-_59753444 2.31 ENST00000594536.5
ENST00000414264.6
myoregulin
chr2_-_127220293 2.25 ENST00000664447.2
ENST00000409327.2
cytochrome P450 family 27 subfamily C member 1
chr11_+_123902167 2.24 ENST00000641687.1
olfactory receptor family 8 subfamily D member 4
chrX_-_38327496 2.17 ENST00000642395.2
ENST00000645032.1
ENST00000644238.1
ENST00000642558.1
ENST00000339363.7
ENST00000644337.1
ENST00000647261.1
retinitis pigmentosa GTPase regulator
chr1_-_31373067 2.16 ENST00000373713.7
fatty acid binding protein 3
chr10_-_49762276 2.09 ENST00000374103.9
oxoglutarate dehydrogenase L
chr14_+_96256194 2.09 ENST00000216629.11
ENST00000553356.1
bradykinin receptor B1
chr8_-_132481057 2.09 ENST00000388996.10
potassium voltage-gated channel subfamily Q member 3
chr1_+_13585453 2.04 ENST00000487038.5
ENST00000475043.5
podoplanin
chr1_-_16437416 2.02 ENST00000375577.5
ENST00000335496.5
spermatogenesis associated 21
chr17_+_4932248 1.98 ENST00000329125.6
glycoprotein Ib platelet subunit alpha
chr19_-_47484176 1.92 ENST00000595554.1
ENST00000338134.8
ENST00000600271.5
kaptin, actin binding protein
chr1_-_207051202 1.90 ENST00000315927.9
YOD1 deubiquitinase
chr17_-_41397600 1.88 ENST00000251645.3
keratin 31
chrX_-_48411910 1.81 ENST00000619890.1
ENST00000595235.6
SSX family member 4B
chr1_+_78303865 1.78 ENST00000370758.5
prostaglandin F receptor
chr1_-_216805367 1.76 ENST00000360012.7
estrogen related receptor gamma
chr9_-_95507416 1.70 ENST00000429896.6
patched 1
chr14_-_102240597 1.68 ENST00000523231.5
ENST00000524370.5
ENST00000517966.5
MOK protein kinase
chr17_-_41382298 1.67 ENST00000394001.3
keratin 34
chr1_-_111427731 1.67 ENST00000369732.4
oviductal glycoprotein 1
chr16_-_66730216 1.67 ENST00000569320.5
dynein cytoplasmic 1 light intermediate chain 2
chr5_-_161546671 1.66 ENST00000517547.5
gamma-aminobutyric acid type A receptor subunit beta2
chr12_+_120725796 1.66 ENST00000242592.9
ENST00000411593.2
acyl-CoA dehydrogenase short chain
chr22_-_38181772 1.62 ENST00000430886.5
ENST00000667521.1
ENST00000663895.1
ENST00000402064.5
ENST00000332509.8
ENST00000664587.1
phospholipase A2 group VI
chr4_+_89901979 1.62 ENST00000508372.1
multimerin 1
chr20_+_21125981 1.60 ENST00000619574.4
kizuna centrosomal protein
chr5_+_102808057 1.60 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr19_-_6279921 1.59 ENST00000252674.9
MLLT1 super elongation complex subunit
chr22_+_39520553 1.58 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
activating transcription factor 4
chr20_+_21125999 1.56 ENST00000620891.4
kizuna centrosomal protein
chr22_+_18150162 1.56 ENST00000215794.8
ubiquitin specific peptidase 18
chr20_+_21126037 1.53 ENST00000611685.4
ENST00000616848.4
kizuna centrosomal protein
chr22_-_38181707 1.48 ENST00000668949.1
ENST00000335539.7
phospholipase A2 group VI
chr11_+_62270150 1.47 ENST00000525380.1
ENST00000227918.3
secretoglobin family 2A member 2
chr15_-_99249523 1.44 ENST00000560235.1
ENST00000394132.7
ENST00000560860.5
ENST00000558078.5
ENST00000560772.5
tetratricopeptide repeat domain 23
chr17_-_41350824 1.43 ENST00000007735.4
keratin 33A
chr11_-_10568571 1.42 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr1_-_46176482 1.39 ENST00000540385.2
ENST00000506599.2
P3R3URF-PIK3R3 readthrough
PIK3R3 upstream reading frame
chr8_+_84705920 1.39 ENST00000523850.5
ENST00000521376.1
RALY RNA binding protein like
chr1_+_100352451 1.39 ENST00000361544.11
ENST00000370124.8
ENST00000336454.5
cell division cycle 14A
chr3_+_129440196 1.38 ENST00000507564.5
ENST00000348417.7
ENST00000504021.5
ENST00000349441.6
intraflagellar transport 122
chr4_-_169612571 1.37 ENST00000507142.6
ENST00000510533.5
ENST00000439128.6
ENST00000511633.5
ENST00000512193.5
NIMA related kinase 1
chr1_+_84144260 1.35 ENST00000370685.7
protein kinase cAMP-activated catalytic subunit beta
chr17_-_58692032 1.31 ENST00000349033.10
ENST00000389934.7
testis expressed 14, intercellular bridge forming factor
chr4_+_70028452 1.29 ENST00000530128.5
ENST00000381057.3
ENST00000673563.1
histatin 3
chr11_-_5154757 1.28 ENST00000380367.3
olfactory receptor family 52 subfamily A member 1
chr9_-_21228222 1.26 ENST00000413767.2
interferon alpha 17
chr11_+_7088991 1.23 ENST00000306904.7
RBMX like 2
chr4_-_89057156 1.23 ENST00000511976.5
ENST00000509094.5
ENST00000264344.10
ENST00000515600.1
family with sequence similarity 13 member A
chr2_+_203867764 1.22 ENST00000648405.2
cytotoxic T-lymphocyte associated protein 4
chr19_+_852295 1.22 ENST00000263621.2
elastase, neutrophil expressed
chr3_+_46577778 1.16 ENST00000296145.6
teratocarcinoma-derived growth factor 1
chr11_+_61248122 1.15 ENST00000451616.6
pepsinogen A5
chrX_+_50067576 1.14 ENST00000376108.7
chloride voltage-gated channel 5
chr15_-_55588937 1.13 ENST00000302000.10
pygopus family PHD finger 1
chr11_-_10568650 1.13 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr4_+_155903688 1.12 ENST00000536354.3
tryptophan 2,3-dioxygenase
chr5_+_162067990 1.12 ENST00000641017.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr4_-_17512079 1.10 ENST00000428702.6
ENST00000508623.5
ENST00000513615.5
ENST00000281243.10
quinoid dihydropteridine reductase
chr11_+_61228377 1.09 ENST00000537932.5
pepsinogen A4
chr19_+_35282520 1.08 ENST00000222304.5
hepcidin antimicrobial peptide
chr21_+_38272250 1.05 ENST00000398932.5
potassium inwardly rectifying channel subfamily J member 15
chr3_-_197949869 1.04 ENST00000452735.1
ENST00000453254.5
ENST00000455191.5
IQ motif containing G
chr2_-_178072751 1.04 ENST00000286063.11
phosphodiesterase 11A
chr21_+_38272291 1.03 ENST00000438657.5
potassium inwardly rectifying channel subfamily J member 15
chr4_-_119322128 1.03 ENST00000274024.4
fatty acid binding protein 2
chr1_-_66801276 1.03 ENST00000304526.3
insulin like 5
chr5_-_161546970 1.01 ENST00000675303.1
gamma-aminobutyric acid type A receptor subunit beta2
chr13_-_36370171 1.00 ENST00000355182.8
spartin
chr17_+_59155726 0.97 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr12_-_4538440 0.97 ENST00000261250.8
ENST00000541014.5
ENST00000545746.5
ENST00000542080.5
chromosome 12 open reading frame 4
chr5_-_161546708 0.95 ENST00000393959.6
gamma-aminobutyric acid type A receptor subunit beta2
chr15_-_41544243 0.93 ENST00000567866.5
ENST00000304330.9
ENST00000561603.5
ENST00000566863.1
RNA polymerase II associated protein 1
chr6_+_148747016 0.88 ENST00000367463.5
uronyl 2-sulfotransferase
chr17_-_58692021 0.86 ENST00000240361.12
testis expressed 14, intercellular bridge forming factor
chr12_-_52434363 0.86 ENST00000252245.6
keratin 75
chr3_-_52830664 0.85 ENST00000266041.9
ENST00000406595.5
ENST00000485816.5
inter-alpha-trypsin inhibitor heavy chain 4
chr20_+_38962299 0.85 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr5_-_22853320 0.84 ENST00000504376.6
ENST00000382254.6
cadherin 12
chrX_-_63785149 0.81 ENST00000671741.2
ENST00000625116.3
ENST00000624355.1
Cdc42 guanine nucleotide exchange factor 9
chr7_-_27130182 0.79 ENST00000511914.1
homeobox A4
chr1_+_78045956 0.78 ENST00000370759.4
GIPC PDZ domain containing family member 2
chr3_+_190615308 0.74 ENST00000412080.1
interleukin 1 receptor accessory protein
chr1_+_84181630 0.74 ENST00000610457.1
protein kinase cAMP-activated catalytic subunit beta
chr2_+_33134579 0.73 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr5_-_79512794 0.73 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
homer scaffold protein 1
chr14_+_24070837 0.72 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
copine 6
chr11_-_102798148 0.72 ENST00000315274.7
matrix metallopeptidase 1
chr3_-_122793772 0.71 ENST00000306103.3
HSPB1 associated protein 1
chr3_-_116444983 0.70 ENST00000333617.8
limbic system associated membrane protein
chr21_+_38272410 0.69 ENST00000398934.5
ENST00000398930.5
potassium inwardly rectifying channel subfamily J member 15
chrX_+_101623121 0.68 ENST00000491568.6
ENST00000479298.5
ENST00000471229.7
armadillo repeat containing X-linked 3
chr2_+_33134620 0.68 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr1_-_173207322 0.68 ENST00000281834.4
TNF superfamily member 4
chr7_+_138076453 0.66 ENST00000242375.8
ENST00000411726.6
aldo-keto reductase family 1 member D1
chr13_-_36370111 0.64 ENST00000650221.1
spartin
chr4_-_81214960 0.62 ENST00000395578.3
ENST00000628926.1
protein kinase cGMP-dependent 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 31.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
4.8 14.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
3.4 13.5 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.8 7.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
1.7 5.1 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
1.7 5.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.4 4.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
1.4 5.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.1 4.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.1 7.9 GO:0033591 response to L-ascorbic acid(GO:0033591)
1.1 5.6 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.9 3.5 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.9 7.8 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.9 6.8 GO:0060155 platelet dense granule organization(GO:0060155)
0.8 5.8 GO:0015705 iodide transport(GO:0015705)
0.8 7.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.8 2.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.8 7.3 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.8 1.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.8 3.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.7 6.0 GO:0042118 endothelial cell activation(GO:0042118)
0.6 1.9 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.6 8.2 GO:0034465 response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.6 8.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.6 2.3 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.6 1.7 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.5 2.7 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.5 4.8 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5 2.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.5 1.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.5 3.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.4 1.7 GO:0010157 response to chlorate(GO:0010157)
0.4 3.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.4 9.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.4 1.6 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.4 6.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.4 1.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.4 2.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.4 5.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.4 3.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 2.1 GO:0097338 response to clozapine(GO:0097338)
0.3 2.2 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.3 4.6 GO:0042574 retinal metabolic process(GO:0042574)
0.3 3.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 3.8 GO:0006554 lysine catabolic process(GO:0006554) thyroid hormone transport(GO:0070327)
0.3 2.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.2 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.2 3.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 1.8 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.2 0.7 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 3.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 0.6 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.2 1.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 9.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 5.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 1.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 0.6 GO:0035565 regulation of pronephros size(GO:0035565)
0.2 1.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.2 2.7 GO:0035878 nail development(GO:0035878)
0.2 0.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 2.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 4.7 GO:0071420 cellular response to histamine(GO:0071420)
0.2 2.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 2.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 1.1 GO:0010044 response to aluminum ion(GO:0010044)
0.1 1.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 2.3 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 1.0 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 2.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 0.5 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 3.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 4.1 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 0.3 GO:0052314 serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314)
0.1 1.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.7 GO:0072564 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 2.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.5 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 2.8 GO:0015695 organic cation transport(GO:0015695)
0.1 1.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 1.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 2.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 7.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 2.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 3.2 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 0.5 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 0.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 3.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 2.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.7 GO:0051642 centrosome localization(GO:0051642)
0.0 1.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 2.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 2.2 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.2 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 7.9 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 1.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 1.6 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 2.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 3.7 GO:0070268 cornification(GO:0070268)
0.0 13.9 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 0.5 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 1.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 4.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.0 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 6.1 GO:0000819 sister chromatid segregation(GO:0000819)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.7 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 1.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 4.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 13.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.9 3.6 GO:0000801 central element(GO:0000801)
0.8 13.5 GO:0005922 connexon complex(GO:0005922)
0.7 5.8 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.7 7.8 GO:0005955 calcineurin complex(GO:0005955)
0.7 2.7 GO:0035363 histone locus body(GO:0035363)
0.6 4.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.6 8.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 2.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.6 1.7 GO:0030312 external encapsulating structure(GO:0030312)
0.5 1.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.5 5.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 10.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.4 3.5 GO:0071953 elastic fiber(GO:0071953)
0.3 1.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.3 18.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 3.8 GO:0033270 paranode region of axon(GO:0033270)
0.2 3.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 3.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 2.3 GO:0042587 glycogen granule(GO:0042587)
0.2 5.1 GO:0043194 axon initial segment(GO:0043194)
0.2 1.4 GO:0060091 kinocilium(GO:0060091)
0.2 1.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.2 2.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.2 3.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 7.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 6.4 GO:0097546 ciliary base(GO:0097546)
0.2 6.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.0 GO:0002177 manchette(GO:0002177)
0.2 3.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 1.1 GO:0045179 apical cortex(GO:0045179)
0.1 4.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 3.9 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 4.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 14.1 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 8.2 GO:0005901 caveola(GO:0005901)
0.1 2.5 GO:0051233 spindle midzone(GO:0051233)
0.1 3.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.8 GO:0045095 keratin filament(GO:0045095)
0.1 1.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.9 GO:0032420 stereocilium(GO:0032420)
0.0 2.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.5 GO:0016528 sarcoplasm(GO:0016528)
0.0 6.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 7.0 GO:0044306 neuron projection terminus(GO:0044306)
0.0 8.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.9 GO:0005882 intermediate filament(GO:0005882)
0.0 5.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 1.6 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 10.1 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 3.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 5.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 3.5 GO:0030027 lamellipodium(GO:0030027)
0.0 5.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 2.5 GO:0030424 axon(GO:0030424)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 18.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.3 13.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
1.9 9.6 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
1.5 8.8 GO:0015057 thrombin receptor activity(GO:0015057)
1.5 7.3 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
1.0 13.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.0 7.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.9 3.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.9 8.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.9 4.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.7 2.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.7 4.3 GO:0043237 laminin-1 binding(GO:0043237)
0.7 2.2 GO:0070538 oleic acid binding(GO:0070538)
0.7 14.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 1.9 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.6 1.8 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.5 4.8 GO:0005549 odorant binding(GO:0005549)
0.4 1.7 GO:0097108 hedgehog family protein binding(GO:0097108)
0.4 1.6 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.4 1.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.4 3.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3 14.5 GO:0017091 AU-rich element binding(GO:0017091)
0.3 3.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.3 4.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 5.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 3.1 GO:0004064 arylesterase activity(GO:0004064)
0.3 6.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 3.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 1.4 GO:0050436 microfibril binding(GO:0050436)
0.3 1.1 GO:0070404 NADH binding(GO:0070404)
0.3 1.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 3.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 3.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 2.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 14.3 GO:0015485 cholesterol binding(GO:0015485)
0.2 2.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 3.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 0.7 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.2 5.0 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.2 17.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 3.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 4.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 5.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 3.5 GO:0005522 profilin binding(GO:0005522)
0.2 2.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.7 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.2 3.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 4.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 1.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 3.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 10.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 2.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 2.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 2.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 2.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 5.8 GO:0043621 protein self-association(GO:0043621)
0.1 7.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.6 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 3.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 6.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 3.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 4.5 GO:0005179 hormone activity(GO:0005179)
0.0 1.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 3.5 GO:0005178 integrin binding(GO:0005178)
0.0 2.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 3.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0019956 chemokine binding(GO:0019956)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 2.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 1.2 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 3.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 25.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.4 28.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.3 7.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 13.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 14.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 23.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.6 PID AURORA B PATHWAY Aurora B signaling
0.1 3.1 PID RAS PATHWAY Regulation of Ras family activation
0.1 6.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 2.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.1 PID IL3 PATHWAY IL3-mediated signaling events
0.1 3.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.9 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 3.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 4.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.4 10.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 5.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 12.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 6.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 7.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 15.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 14.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 3.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 3.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 4.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 6.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 5.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 3.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 3.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 2.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 11.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.7 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 3.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 5.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 4.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.6 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 2.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.6 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 3.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.9 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 3.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions