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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXA9

Z-value: 0.75

Motif logo

Transcription factors associated with HOXA9

Gene Symbol Gene ID Gene Info
ENSG00000078399.19 HOXA9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA9hg38_v1_chr7_-_27165517_271655450.036.6e-01Click!

Activity profile of HOXA9 motif

Sorted Z-values of HOXA9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA9

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_-_13817346 20.53 ENST00000356942.9
glycoprotein M6B
chrX_-_13817027 13.95 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr3_-_195583931 10.99 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr2_+_20447065 10.55 ENST00000272233.6
ras homolog family member B
chr3_-_58627596 9.40 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr2_+_112275588 9.40 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr8_+_79611036 8.69 ENST00000220876.12
ENST00000518111.5
stathmin 2
chr2_-_223602284 7.70 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr14_+_92323154 7.05 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr3_+_41200104 6.89 ENST00000643297.1
ENST00000450969.6
catenin beta 1
chr17_-_68955332 6.29 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr12_-_91179472 6.12 ENST00000550099.5
ENST00000546391.5
decorin
chr17_-_31297231 6.07 ENST00000247271.5
oligodendrocyte myelin glycoprotein
chr9_-_92878018 6.02 ENST00000332591.6
ENST00000375495.8
ENST00000395505.6
ENST00000395506.7
zinc finger protein 484
chr13_-_30307539 5.85 ENST00000380615.8
katanin catalytic subunit A1 like 1
chr4_-_175812746 5.58 ENST00000393658.6
glycoprotein M6A
chr10_-_46046264 5.44 ENST00000581478.5
ENST00000582163.3
microseminoprotein beta
chr4_-_185810894 5.12 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chrX_+_66164340 5.01 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
hephaestin
chr18_+_74597850 4.73 ENST00000582337.5
ENST00000299687.10
zinc finger protein 407
chr3_-_197959977 4.72 ENST00000265239.11
IQ motif containing G
chr3_+_148827800 4.56 ENST00000282957.9
ENST00000468341.1
carboxypeptidase B1
chr2_-_152098810 4.53 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr5_-_112419251 4.45 ENST00000261486.6
erythrocyte membrane protein band 4.1 like 4A
chr9_-_83956677 4.35 ENST00000376344.8
chromosome 9 open reading frame 64
chr11_+_72216774 4.24 ENST00000619261.4
ENST00000454954.6
ENST00000541003.5
ENST00000539412.5
ENST00000298223.11
ENST00000536778.5
ENST00000535625.5
ENST00000321324.11
folate receptor beta
chr2_-_88128049 4.23 ENST00000393750.3
ENST00000295834.8
fatty acid binding protein 1
chr4_+_113049479 4.14 ENST00000671727.1
ENST00000671762.1
ENST00000672366.1
ENST00000672502.1
ENST00000672045.1
ENST00000672251.1
ENST00000672854.1
ankyrin 2
chr2_-_2324642 4.05 ENST00000650485.1
ENST00000649207.1
myelin transcription factor 1 like
chr17_-_8118489 4.04 ENST00000380149.6
ENST00000448843.7
arachidonate lipoxygenase 3
chr4_-_48016631 4.03 ENST00000513178.2
ENST00000514170.7
cyclic nucleotide gated channel subunit alpha 1
chr4_+_153153023 4.01 ENST00000676458.1
ENST00000675782.1
tripartite motif containing 2
chr14_-_31457495 3.99 ENST00000310850.9
D-aminoacyl-tRNA deacylase 2
chr22_+_22906342 3.95 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr11_-_5254741 3.88 ENST00000444587.1
ENST00000336906.6
ENST00000642908.1
ENST00000647543.1
hemoglobin subunit gamma 2
novel protein
chr13_+_53028806 3.79 ENST00000219022.3
olfactomedin 4
chr22_+_22822658 3.77 ENST00000620395.2
immunoglobulin lambda variable 2-8
chr6_+_125919296 3.64 ENST00000444128.2
nuclear receptor coactivator 7
chr11_+_62123991 3.51 ENST00000533896.5
ENST00000278849.4
ENST00000394818.8
inner centromere protein
chr7_+_144048948 3.48 ENST00000641693.1
olfactory receptor family 2 subfamily A member 5
chr10_+_122560639 3.45 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr4_+_113049616 3.45 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr4_+_153153105 3.38 ENST00000437508.7
tripartite motif containing 2
chr21_-_28885347 3.37 ENST00000303775.10
ENST00000351429.7
N-6 adenine-specific DNA methyltransferase 1
chr16_+_15502266 3.31 ENST00000452191.6
bMERB domain containing 1
chr2_+_32277883 3.30 ENST00000238831.9
Yip1 domain family member 4
chr2_+_89947508 3.24 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr10_+_122560679 3.24 ENST00000657942.1
deleted in malignant brain tumors 1
chr1_+_92168915 3.17 ENST00000637221.2
BTB domain containing 8
chr10_-_44978789 3.16 ENST00000448778.1
ENST00000298295.4
DEPP1 autophagy regulator
chr10_+_100462969 3.15 ENST00000343737.6
Wnt family member 8B
chr1_+_50109620 3.14 ENST00000371819.1
ELAV like RNA binding protein 4
chr10_-_69416912 3.06 ENST00000373306.5
tachykinin receptor 2
chr7_+_65873091 3.05 ENST00000648187.1
vitamin K epoxide reductase complex subunit 1 like 1
chr3_+_119579676 2.94 ENST00000357003.7
ADP-ribosylarginine hydrolase
chr4_-_68670648 2.93 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr19_+_45467988 2.92 ENST00000615753.4
ENST00000585836.5
ENST00000417353.6
ENST00000591858.5
ENST00000443841.6
ENST00000590335.1
ENST00000353609.8
FosB proto-oncogene, AP-1 transcription factor subunit
chr19_+_44141547 2.92 ENST00000426739.7
ENST00000592437.5
zinc finger protein 234
chr17_+_60677822 2.91 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr4_-_76023489 2.90 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr5_+_140834230 2.88 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr16_-_55833186 2.87 ENST00000361503.8
ENST00000422046.6
carboxylesterase 1
chr6_-_88166339 2.85 ENST00000369501.3
ENST00000551417.2
cannabinoid receptor 1
chr5_+_141392616 2.81 ENST00000398604.3
protocadherin gamma subfamily A, 8
chr10_+_122560751 2.81 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr4_-_145180496 2.71 ENST00000447906.8
OTU deubiquitinase 4
chr7_+_29122274 2.71 ENST00000582692.2
ENST00000644824.1
novel transcript, antisense to CPVL
chimerin 2
chr6_-_27807916 2.68 ENST00000377401.3
H2B clustered histone 13
chr10_-_88952763 2.68 ENST00000224784.10
actin alpha 2, smooth muscle
chr12_-_262828 2.65 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
solute carrier family 6 member 13
chr11_+_60280531 2.64 ENST00000532114.6
membrane spanning 4-domains A4A
chr16_-_20327426 2.63 ENST00000575582.5
ENST00000341642.9
ENST00000381362.8
ENST00000572347.5
ENST00000572478.5
ENST00000302555.10
glycoprotein 2
chr9_-_21351378 2.62 ENST00000380210.1
interferon alpha 6
chr16_+_72054477 2.60 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr1_+_44118813 2.60 ENST00000372299.4
Kruppel like factor 17
chr5_-_132011811 2.60 ENST00000379255.5
ENST00000430403.5
ENST00000357096.5
acyl-CoA synthetase long chain family member 6
chr12_-_48004496 2.59 ENST00000337299.7
collagen type II alpha 1 chain
chr3_+_119579577 2.54 ENST00000478927.5
ADP-ribosylarginine hydrolase
chr6_+_25754699 2.52 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr1_-_7853054 2.50 ENST00000361696.10
urotensin 2
chrX_-_64395417 2.50 ENST00000374852.4
myotubularin related protein 8
chr1_-_95072936 2.49 ENST00000370205.6
ALG14 UDP-N-acetylglucosaminyltransferase subunit
chrX_+_66164210 2.48 ENST00000343002.7
ENST00000336279.9
hephaestin
chr9_-_21368057 2.47 ENST00000449498.2
interferon alpha 13
chr5_+_141387698 2.47 ENST00000615384.1
ENST00000519479.2
protocadherin gamma subfamily B, 4
chr12_-_3873382 2.44 ENST00000228820.9
ENST00000450737.2
ENST00000447133.7
poly(ADP-ribose) polymerase family member 11
chr5_-_95081482 2.43 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
multiple C2 and transmembrane domain containing 1
chr16_-_2858154 2.42 ENST00000571228.1
ENST00000161006.8
serine protease 22
chr9_+_114611206 2.41 ENST00000374049.4
ENST00000288502.9
transmembrane protein 268
chr9_-_124507382 2.40 ENST00000373588.9
ENST00000620110.4
nuclear receptor subfamily 5 group A member 1
chr1_+_100719734 2.40 ENST00000370119.8
ENST00000294728.7
ENST00000347652.6
ENST00000370115.1
vascular cell adhesion molecule 1
chr2_+_102473219 2.35 ENST00000295269.5
solute carrier family 9 member A4
chr21_-_26843063 2.25 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr7_+_16753731 2.24 ENST00000262067.5
tetraspanin 13
chrX_-_130903224 2.22 ENST00000370935.5
ecto-NOX disulfide-thiol exchanger 2
chr2_+_67397297 2.20 ENST00000644028.1
ENST00000272342.6
ETAA1 activator of ATR kinase
chr17_+_29043124 2.19 ENST00000323372.9
pipecolic acid and sarcosine oxidase
chr9_-_21350956 2.18 ENST00000259555.5
interferon alpha 6
chr1_-_79006680 2.15 ENST00000370742.4
ENST00000656841.1
adhesion G protein-coupled receptor L4
chrX_-_130903187 2.12 ENST00000432489.5
ENST00000394363.6
ENST00000338144.8
ecto-NOX disulfide-thiol exchanger 2
chr4_+_101790717 2.11 ENST00000508653.5
ENST00000322953.9
B cell scaffold protein with ankyrin repeats 1
chr4_+_37453914 2.11 ENST00000381980.9
ENST00000508175.5
chromosome 4 open reading frame 19
chr8_-_38150943 2.09 ENST00000276449.9
steroidogenic acute regulatory protein
chr12_-_70754631 2.08 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
protein tyrosine phosphatase receptor type R
chr4_-_98657635 2.04 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
tetraspanin 5
chr2_-_208163588 2.02 ENST00000304502.5
crystallin gamma A
chr9_-_101435760 2.01 ENST00000647789.2
ENST00000616752.1
aldolase, fructose-bisphosphate B
chr3_+_159069252 2.01 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr5_+_150497772 1.99 ENST00000523767.5
N-deacetylase and N-sulfotransferase 1
chr10_-_95069489 1.98 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
cytochrome P450 family 2 subfamily C member 8
chr19_-_51028015 1.97 ENST00000319720.11
kallikrein related peptidase 11
chr15_-_30991415 1.96 ENST00000563714.5
myotubularin related protein 10
chr19_-_10309783 1.95 ENST00000403352.1
ENST00000403903.7
zinc finger GATA like protein 1
chr4_+_48016764 1.94 ENST00000295461.10
NIPA like domain containing 1
chr8_-_6978634 1.93 ENST00000382679.2
defensin alpha 1
chr3_-_52830664 1.92 ENST00000266041.9
ENST00000406595.5
ENST00000485816.5
inter-alpha-trypsin inhibitor heavy chain 4
chr3_+_184812159 1.90 ENST00000625842.3
ENST00000436792.6
ENST00000446204.6
ENST00000422105.5
VPS8 subunit of CORVET complex
chr15_+_26971149 1.90 ENST00000615808.5
gamma-aminobutyric acid type A receptor subunit gamma3
chr16_+_19067606 1.90 ENST00000321998.10
coenzyme Q7, hydroxylase
chr11_-_60184633 1.89 ENST00000529054.5
ENST00000530839.5
ENST00000426738.6
membrane spanning 4-domains A6A
chr10_+_73110375 1.89 ENST00000617744.4
ENST00000544879.5
ENST00000537969.5
ENST00000357321.9
ENST00000349051.9
nudix hydrolase 13
chr16_-_67393486 1.86 ENST00000562206.1
ENST00000393957.7
ENST00000290942.9
tubulin polymerization promoting protein family member 3
chr4_-_70666492 1.85 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr5_+_141421064 1.84 ENST00000518882.2
protocadherin gamma subfamily A, 11
chr2_-_208146150 1.83 ENST00000260988.5
crystallin gamma B
chr10_+_4963406 1.82 ENST00000380872.9
ENST00000442997.5
aldo-keto reductase family 1 member C1
chr12_-_118359105 1.81 ENST00000541186.5
ENST00000539872.5
TAO kinase 3
chr8_-_41797589 1.80 ENST00000347528.8
ENST00000289734.13
ankyrin 1
chr7_+_87152531 1.80 ENST00000432366.6
ENST00000423590.6
ENST00000394703.9
cyclin D binding myb like transcription factor 1
chr3_+_196867856 1.80 ENST00000445299.6
ENST00000323460.10
ENST00000419026.5
SUMO specific peptidase 5
chr20_-_17558811 1.78 ENST00000536626.7
ENST00000377868.6
beaded filament structural protein 1
chr2_-_218993401 1.77 ENST00000453769.1
ENST00000392096.6
ENST00000295728.7
crystallin beta A2
chr3_-_9843942 1.77 ENST00000424438.5
ENST00000433555.1
ENST00000427174.5
ENST00000418713.5
ENST00000433535.6
ENST00000383820.9
ENST00000433972.1
RNA pseudouridine synthase D3
chr8_-_18808837 1.76 ENST00000286485.12
pleckstrin and Sec7 domain containing 3
chr12_+_57460127 1.76 ENST00000532291.5
ENST00000543426.5
ENST00000546141.5
GLI family zinc finger 1
chr7_+_20330893 1.75 ENST00000222573.5
integrin subunit beta 8
chr2_-_153478753 1.75 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr17_-_41734641 1.74 ENST00000347901.9
ENST00000393939.6
ENST00000341193.9
ENST00000310778.5
huntingtin associated protein 1
chr12_-_91111460 1.73 ENST00000266718.5
lumican
chr5_-_147453888 1.72 ENST00000398514.7
dihydropyrimidinase like 3
chr14_+_22508602 1.71 ENST00000390504.1
T cell receptor alpha joining 33
chr11_+_119067774 1.71 ENST00000621676.5
ENST00000614944.4
VPS11 core subunit of CORVET and HOPS complexes
chr21_-_18403754 1.71 ENST00000284885.8
transmembrane serine protease 15
chr6_+_35342535 1.70 ENST00000360694.8
ENST00000418635.6
ENST00000448077.6
peroxisome proliferator activated receptor delta
chr3_+_121567924 1.70 ENST00000334384.5
arginine-fifty homeobox
chr12_+_18262730 1.68 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr1_+_117420597 1.66 ENST00000449370.6
mannosidase alpha class 1A member 2
chr10_+_94762673 1.64 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr2_+_89851723 1.63 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr9_+_61190003 1.63 ENST00000619167.1
SPATA31 subfamily A member 7
chr9_+_60914407 1.62 ENST00000437823.5
SPATA31 subfamily A member 5
chr6_+_32154131 1.60 ENST00000375143.6
ENST00000324816.11
ENST00000424499.1
palmitoyl-protein thioesterase 2
chr9_-_19102887 1.60 ENST00000380502.8
HAUS augmin like complex subunit 6
chr17_+_59220446 1.59 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
glycerophosphodiester phosphodiesterase domain containing 1
chr6_+_35342614 1.58 ENST00000337400.6
ENST00000311565.4
peroxisome proliferator activated receptor delta
chr9_-_15472732 1.58 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr3_-_48089203 1.58 ENST00000468075.2
ENST00000360240.10
microtubule associated protein 4
chr5_-_132011794 1.56 ENST00000650697.1
acyl-CoA synthetase long chain family member 6
chrX_+_41724174 1.55 ENST00000302548.5
G protein-coupled receptor 82
chr12_+_57459782 1.55 ENST00000228682.7
GLI family zinc finger 1
chr10_+_73110494 1.52 ENST00000372997.3
nudix hydrolase 13
chr12_-_7503744 1.52 ENST00000396620.7
ENST00000432237.3
CD163 molecule
chr14_+_104689588 1.52 ENST00000330634.11
ENST00000392634.9
ENST00000675482.1
ENST00000398337.8
inverted formin 2
chr12_+_15322529 1.50 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chr10_+_94938649 1.46 ENST00000461906.1
ENST00000260682.8
cytochrome P450 family 2 subfamily C member 9
chr2_-_165953750 1.46 ENST00000243344.8
ENST00000679799.1
ENST00000679840.1
ENST00000681606.1
ENST00000680448.1
tetratricopeptide repeat domain 21B
chr1_-_72282457 1.46 ENST00000357731.10
neuronal growth regulator 1
chr10_-_50623897 1.41 ENST00000361781.7
ENST00000429490.5
ENST00000619438.4
sphingomyelin synthase 1
chr12_-_104958268 1.40 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
solute carrier family 41 member 2
chr19_+_15944299 1.39 ENST00000641275.1
olfactory receptor family 10 subfamily H member 4
chr3_+_35679614 1.39 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
cAMP regulated phosphoprotein 21
chr16_+_16340328 1.38 ENST00000524823.6
novel member of the nuclear pore complex interacting protein NPIP gene family
chr12_+_106774630 1.38 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8 guanine nucleotide exchange factor B
chr3_+_190615308 1.33 ENST00000412080.1
interleukin 1 receptor accessory protein
chr18_+_58864866 1.29 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
zinc finger protein 532
chr6_+_32154010 1.29 ENST00000375137.6
palmitoyl-protein thioesterase 2
chr4_+_159241016 1.28 ENST00000644902.1
Rap guanine nucleotide exchange factor 2
chr10_-_60572599 1.28 ENST00000503366.5
ankyrin 3
chr4_-_163332589 1.27 ENST00000296533.3
ENST00000509586.5
ENST00000504391.5
ENST00000512819.1
neuropeptide Y receptor Y1
chr22_+_22588155 1.26 ENST00000390302.3
immunoglobulin lambda variable 2-33 (non-functional)
chr12_-_52385649 1.24 ENST00000257951.3
keratin 84
chr9_-_21228222 1.24 ENST00000413767.2
interferon alpha 17
chr16_-_89490479 1.23 ENST00000642600.1
ENST00000301030.10
ankyrin repeat domain 11
chr7_-_14841267 1.22 ENST00000406247.7
ENST00000399322.7
diacylglycerol kinase beta
chr4_-_69961007 1.22 ENST00000353151.3
casein beta
chr18_+_34978244 1.22 ENST00000436190.6
microtubule associated protein RP/EB family member 2
chr19_+_50025989 1.21 ENST00000445728.7
ENST00000270617.8
ENST00000601364.5
zinc finger protein 473
chr2_+_203867764 1.20 ENST00000648405.2
cytotoxic T-lymphocyte associated protein 4
chr3_+_120908072 1.18 ENST00000273666.10
ENST00000471454.6
ENST00000472879.5
ENST00000497029.5
ENST00000492541.5
syntaxin binding protein 5 like
chr2_+_232526153 1.17 ENST00000449596.5
ENST00000258385.8
ENST00000543200.5
cholinergic receptor nicotinic delta subunit
chr10_-_114144599 1.17 ENST00000428953.1
coiled-coil domain containing 186
chr7_-_27152561 1.16 ENST00000467897.2
ENST00000612286.5
ENST00000498652.1
novel transcript
homeobox A3
novel transcript
chr16_+_70523782 1.16 ENST00000566095.6
ENST00000577085.1
ENST00000302516.10
ENST00000567654.1
splicing factor 3b subunit 3
chr1_+_192575765 1.13 ENST00000469578.2
ENST00000367459.8
regulator of G protein signaling 1
chr9_+_470291 1.13 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr7_+_134745460 1.10 ENST00000436461.6
caldesmon 1
chr17_-_58417547 1.09 ENST00000577716.5
ring finger protein 43
chr16_-_88663065 1.09 ENST00000301012.8
ENST00000569177.5
mevalonate diphosphate decarboxylase
chr11_-_105023136 1.09 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr19_+_50025714 1.09 ENST00000598809.5
ENST00000595661.5
ENST00000391821.6
zinc finger protein 473

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
2.9 34.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.2 8.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
1.4 6.9 GO:0007403 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
1.1 3.3 GO:0060032 notochord regression(GO:0060032)
1.1 5.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.1 4.2 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
1.0 5.8 GO:0051013 microtubule severing(GO:0051013)
1.0 2.9 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.9 2.6 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.9 9.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.8 3.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.8 7.6 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.7 2.1 GO:0071373 phthalate metabolic process(GO:0018963) cellular response to luteinizing hormone stimulus(GO:0071373)
0.6 1.9 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.6 2.5 GO:0010841 negative regulation of glomerular filtration(GO:0003105) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.6 3.1 GO:0035106 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.6 2.4 GO:0007538 primary sex determination(GO:0007538)
0.6 1.7 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.6 7.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.5 2.2 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.5 2.7 GO:0090131 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.5 4.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.5 5.1 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.5 4.0 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.5 6.3 GO:0042908 xenobiotic transport(GO:0042908)
0.5 6.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.5 1.8 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.4 2.6 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.4 4.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.4 2.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.4 1.7 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.4 1.2 GO:1903487 regulation of lactation(GO:1903487)
0.4 2.4 GO:0022614 membrane to membrane docking(GO:0022614)
0.4 4.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4 2.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4 7.1 GO:0097186 amelogenesis(GO:0097186)
0.4 1.8 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.4 1.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 1.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.4 3.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.4 1.8 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.3 2.0 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 9.3 GO:0006825 copper ion transport(GO:0006825)
0.3 1.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 3.8 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.3 1.6 GO:0051012 microtubule sliding(GO:0051012)
0.3 1.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.3 4.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.3 1.8 GO:0016926 protein desumoylation(GO:0016926)
0.3 0.9 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.3 1.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 10.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 1.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 5.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.3 3.0 GO:0042373 vitamin K metabolic process(GO:0042373)
0.3 3.3 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.3 0.8 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.3 2.9 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.3 2.9 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.3 7.5 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.3 3.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.3 1.5 GO:0001692 histamine metabolic process(GO:0001692)
0.2 2.0 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 2.1 GO:0015693 magnesium ion transport(GO:0015693)
0.2 1.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.2 1.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 0.6 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.2 3.9 GO:0015671 oxygen transport(GO:0015671)
0.2 1.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 2.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.2 2.1 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.2 3.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 1.3 GO:0072602 interleukin-33-mediated signaling pathway(GO:0038172) interleukin-4 secretion(GO:0072602)
0.2 1.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 0.7 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.2 0.6 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 1.8 GO:0070307 lens fiber cell development(GO:0070307)
0.2 1.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 2.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 1.7 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 1.2 GO:0035878 nail development(GO:0035878)
0.2 1.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 0.9 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 1.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 5.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 2.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 2.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 4.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 3.0 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 1.0 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 5.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.9 GO:0051412 response to corticosterone(GO:0051412)
0.1 2.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 4.0 GO:0048665 neuron fate specification(GO:0048665)
0.1 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 5.9 GO:0006400 tRNA modification(GO:0006400)
0.1 6.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 3.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.8 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.8 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 2.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 1.8 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 6.1 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 1.0 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 1.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.9 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.2 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 4.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.6 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 1.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.7 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 2.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.5 GO:0006552 leucine catabolic process(GO:0006552)
0.0 5.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.9 GO:0048599 oocyte development(GO:0048599)
0.0 0.6 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 1.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 5.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.6 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 2.4 GO:0009988 cell-cell recognition(GO:0009988)
0.0 2.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 2.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 2.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 2.2 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 2.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.9 GO:0070206 protein trimerization(GO:0070206)
0.0 0.3 GO:0034030 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 6.5 GO:0016049 cell growth(GO:0016049)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 1.0 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0033572 transferrin transport(GO:0033572)
0.0 6.5 GO:0007276 gamete generation(GO:0007276)
0.0 2.3 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.6 GO:0042246 tissue regeneration(GO:0042246)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.9 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.9 2.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.9 3.5 GO:0000801 central element(GO:0000801)
0.8 2.4 GO:0071756 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.8 2.4 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.8 4.7 GO:0002177 manchette(GO:0002177)
0.7 2.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 1.8 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.6 10.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.5 4.2 GO:0045179 apical cortex(GO:0045179)
0.5 1.9 GO:0033263 CORVET complex(GO:0033263)
0.5 6.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.4 7.7 GO:0031045 dense core granule(GO:0031045)
0.4 1.6 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.3 3.9 GO:0005833 hemoglobin complex(GO:0005833)
0.2 4.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 5.6 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 2.1 GO:0030061 mitochondrial crista(GO:0030061)
0.2 1.6 GO:0070652 HAUS complex(GO:0070652)
0.2 4.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 1.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 1.9 GO:0097427 microtubule bundle(GO:0097427)
0.2 2.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 8.9 GO:0043034 costamere(GO:0043034)
0.1 1.7 GO:0030897 HOPS complex(GO:0030897)
0.1 1.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 7.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.8 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 6.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 16.3 GO:0030426 growth cone(GO:0030426)
0.1 10.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.3 GO:0097546 ciliary base(GO:0097546)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 4.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 25.5 GO:0045121 membrane raft(GO:0045121)
0.1 2.0 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.0 2.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 11.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 6.7 GO:0072562 blood microparticle(GO:0072562)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.2 GO:0005604 basement membrane(GO:0005604)
0.0 7.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 5.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.1 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 2.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.6 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 24.9 GO:0005615 extracellular space(GO:0005615)
0.0 2.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 54.2 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.5 GO:0035375 zymogen binding(GO:0035375)
1.4 5.5 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
1.2 7.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
1.1 4.2 GO:0061714 folic acid receptor activity(GO:0061714)
1.0 8.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.0 3.1 GO:0016497 substance K receptor activity(GO:0016497)
1.0 2.9 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.8 5.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.8 2.5 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.8 4.0 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.7 3.4 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.7 2.0 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.7 4.0 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.6 1.8 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.6 4.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.6 2.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.6 2.9 GO:0047374 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.6 6.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.5 3.0 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.5 2.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.5 1.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 1.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.4 1.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 2.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.4 1.7 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.4 1.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.4 4.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.4 6.9 GO:0070411 I-SMAD binding(GO:0070411)
0.4 1.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 5.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.4 2.6 GO:0030492 hemoglobin binding(GO:0030492)
0.4 1.9 GO:0019862 IgA binding(GO:0019862)
0.4 2.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 2.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.3 3.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 1.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 0.9 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3 1.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.3 1.6 GO:0097100 supercoiled DNA binding(GO:0097100)
0.3 2.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 7.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 2.4 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.2 0.6 GO:0005135 erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135)
0.2 5.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 1.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 1.3 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 6.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 0.7 GO:0047115 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.2 7.8 GO:0042056 chemoattractant activity(GO:0042056)
0.2 1.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 10.7 GO:0030507 spectrin binding(GO:0030507)
0.2 5.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 2.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 2.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 1.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.5 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 4.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 4.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 4.2 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 1.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 4.2 GO:0005109 frizzled binding(GO:0005109)
0.1 1.9 GO:0008252 nucleotidase activity(GO:0008252)
0.1 2.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 3.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.6 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 3.6 GO:0015485 cholesterol binding(GO:0015485)
0.1 6.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.1 0.7 GO:0005549 odorant binding(GO:0005549)
0.1 1.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 2.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1 14.6 GO:0003823 antigen binding(GO:0003823)
0.1 1.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 9.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 3.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 5.6 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.0 1.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 2.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 3.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 14.8 GO:0015631 tubulin binding(GO:0015631)
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 7.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 2.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 1.3 GO:0004497 monooxygenase activity(GO:0004497)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.1 GO:0008276 protein methyltransferase activity(GO:0008276)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 6.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 2.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 4.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 17.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 6.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 5.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 3.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 9.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 6.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 6.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 5.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 10.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 6.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 6.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 5.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 5.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 2.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 6.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.9 REACTOME DEFENSINS Genes involved in Defensins
0.1 1.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 5.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 3.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.8 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 6.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 4.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 9.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 4.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 2.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 3.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 5.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation