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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for HOXC8
Z-value: 1.38
Motif logo
Transcription factors associated with HOXC8
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXC8
|
ENSG00000037965.6 | HOXC8 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXC8 | hg38_v1_chr12_+_54008961_54009005 | -0.58 | 1.2e-20 | Click! |
Activity profile of HOXC8 motif
Sorted Z-values of HOXC8 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC8
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.8 | 51.2 | GO:0002188 | translation reinitiation(GO:0002188) |
| 6.0 | 30.2 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 5.9 | 23.5 | GO:0006238 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 5.9 | 17.6 | GO:0006714 | sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224) |
| 4.9 | 43.9 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 4.6 | 13.8 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 4.3 | 17.4 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 4.2 | 12.7 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 4.2 | 8.4 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 4.2 | 12.5 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 3.9 | 11.6 | GO:0036111 | very long-chain fatty-acyl-CoA metabolic process(GO:0036111) |
| 3.9 | 23.2 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 3.8 | 11.5 | GO:0009106 | lipoate metabolic process(GO:0009106) |
| 3.8 | 7.6 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 3.8 | 18.9 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 3.7 | 15.0 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
| 3.6 | 50.4 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 3.5 | 10.5 | GO:1904387 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 3.5 | 45.3 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 3.4 | 27.4 | GO:0014038 | regulation of Schwann cell differentiation(GO:0014038) |
| 3.3 | 23.1 | GO:0045653 | histone H4-R3 methylation(GO:0043985) negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 3.3 | 9.9 | GO:1902594 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 3.2 | 9.6 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 3.1 | 9.4 | GO:1900195 | spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195) |
| 3.1 | 21.6 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 2.9 | 8.8 | GO:0006679 | glucosylceramide biosynthetic process(GO:0006679) |
| 2.9 | 23.2 | GO:0007144 | female meiosis I(GO:0007144) |
| 2.9 | 25.7 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 2.8 | 11.2 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 2.8 | 5.6 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 2.7 | 13.6 | GO:0033383 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 2.7 | 13.5 | GO:1902904 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 2.6 | 10.5 | GO:1904977 | lymphatic endothelial cell migration(GO:1904977) |
| 2.6 | 13.1 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
| 2.6 | 7.7 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 2.5 | 27.4 | GO:1903943 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 2.5 | 9.9 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 2.5 | 9.8 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 2.4 | 7.2 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 2.4 | 9.6 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 2.3 | 13.9 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 2.3 | 6.9 | GO:0043974 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) |
| 2.3 | 11.5 | GO:0051792 | medium-chain fatty acid biosynthetic process(GO:0051792) |
| 2.3 | 9.1 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 2.2 | 6.7 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 2.2 | 8.7 | GO:0072185 | metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 2.2 | 8.7 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 2.1 | 8.6 | GO:1902775 | mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 2.1 | 8.4 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 2.1 | 6.2 | GO:0072019 | proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) |
| 2.1 | 10.3 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 2.0 | 8.2 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 2.0 | 8.1 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 2.0 | 6.1 | GO:1902568 | positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
| 2.0 | 6.0 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 1.9 | 7.7 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 1.9 | 5.6 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 1.8 | 12.9 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 1.8 | 10.9 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 1.8 | 5.3 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 1.7 | 15.5 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 1.7 | 5.1 | GO:0031455 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 1.6 | 11.2 | GO:1901977 | negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002) |
| 1.6 | 11.2 | GO:0009249 | protein lipoylation(GO:0009249) |
| 1.6 | 8.0 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 1.6 | 14.3 | GO:0006265 | DNA topological change(GO:0006265) |
| 1.6 | 11.1 | GO:0097680 | cellular hyperosmotic salinity response(GO:0071475) double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 1.6 | 4.8 | GO:1903015 | regulation of exo-alpha-sialidase activity(GO:1903015) |
| 1.6 | 20.5 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 1.6 | 61.3 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 1.6 | 6.3 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 1.5 | 6.2 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 1.5 | 78.2 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 1.5 | 4.6 | GO:0034473 | U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) |
| 1.5 | 7.6 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 1.5 | 15.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 1.5 | 7.5 | GO:1903027 | regulation of opsonization(GO:1903027) |
| 1.5 | 12.0 | GO:0072733 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 1.5 | 5.9 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 1.4 | 8.7 | GO:0070101 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101) |
| 1.4 | 7.0 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 1.4 | 9.8 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 1.4 | 7.0 | GO:0060613 | fat pad development(GO:0060613) |
| 1.4 | 4.2 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 1.4 | 6.9 | GO:0001971 | negative regulation of activation of membrane attack complex(GO:0001971) |
| 1.4 | 4.1 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 1.4 | 4.1 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 1.4 | 8.2 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 1.3 | 5.3 | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process(GO:2001247) |
| 1.3 | 7.9 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 1.3 | 9.2 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 1.3 | 7.8 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 1.3 | 19.4 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 1.3 | 30.8 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 1.2 | 7.5 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 1.2 | 5.0 | GO:0009753 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 1.2 | 3.7 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 1.2 | 7.4 | GO:1904016 | response to Thyroglobulin triiodothyronine(GO:1904016) |
| 1.2 | 3.7 | GO:0097212 | cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822) |
| 1.2 | 8.5 | GO:0032328 | alanine transport(GO:0032328) |
| 1.2 | 6.0 | GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 1.2 | 2.4 | GO:1903753 | negative regulation of p38MAPK cascade(GO:1903753) |
| 1.2 | 4.7 | GO:0030961 | peptidyl-arginine hydroxylation(GO:0030961) |
| 1.2 | 5.9 | GO:0040030 | regulation of molecular function, epigenetic(GO:0040030) |
| 1.1 | 4.5 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 1.1 | 15.7 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 1.1 | 2.2 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 1.1 | 5.6 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 1.1 | 5.6 | GO:1902896 | terminal web assembly(GO:1902896) |
| 1.1 | 6.6 | GO:0061205 | alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205) |
| 1.1 | 7.6 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 1.1 | 7.5 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 1.1 | 13.7 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 1.0 | 5.2 | GO:0042374 | phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662) |
| 1.0 | 5.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 1.0 | 4.0 | GO:0035927 | RNA import into mitochondrion(GO:0035927) |
| 1.0 | 6.0 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 1.0 | 2.0 | GO:0014740 | negative regulation of muscle hyperplasia(GO:0014740) |
| 1.0 | 9.9 | GO:0097647 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 1.0 | 5.9 | GO:1901896 | positive regulation of calcium-transporting ATPase activity(GO:1901896) |
| 1.0 | 12.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 1.0 | 31.2 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 1.0 | 5.7 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.9 | 5.7 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.9 | 11.1 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 0.9 | 7.3 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.9 | 19.9 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.9 | 2.7 | GO:1904907 | regulation of maintenance of sister chromatid cohesion(GO:0034091) negative regulation of maintenance of sister chromatid cohesion(GO:0034092) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908) |
| 0.9 | 4.5 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.9 | 11.6 | GO:0042407 | cristae formation(GO:0042407) |
| 0.9 | 9.8 | GO:0051775 | response to redox state(GO:0051775) |
| 0.9 | 12.4 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.9 | 2.6 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.9 | 5.3 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.9 | 2.6 | GO:0002305 | gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305) |
| 0.9 | 3.5 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 0.9 | 4.3 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.9 | 60.7 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.8 | 3.4 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 0.8 | 1.7 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.8 | 5.0 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.8 | 7.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.8 | 14.0 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.8 | 10.6 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.8 | 11.4 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.8 | 12.1 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) |
| 0.8 | 3.2 | GO:0042450 | arginine biosynthetic process via ornithine(GO:0042450) |
| 0.8 | 5.6 | GO:0060242 | contact inhibition(GO:0060242) |
| 0.8 | 15.1 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.8 | 2.4 | GO:1901388 | regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389) |
| 0.8 | 14.8 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.8 | 2.3 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 0.8 | 3.1 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) |
| 0.8 | 7.7 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.8 | 3.8 | GO:0032532 | regulation of microvillus length(GO:0032532) |
| 0.8 | 2.3 | GO:1990426 | homologous recombination-dependent replication fork processing(GO:1990426) |
| 0.8 | 80.4 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
| 0.8 | 6.0 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.7 | 6.7 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 0.7 | 3.7 | GO:0097240 | telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.7 | 9.5 | GO:2000774 | positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774) |
| 0.7 | 7.9 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.7 | 5.7 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) |
| 0.7 | 2.2 | GO:0043321 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.7 | 2.8 | GO:0006408 | snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833) snRNA transport(GO:0051030) |
| 0.7 | 4.9 | GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) |
| 0.7 | 7.6 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.7 | 5.5 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.7 | 2.0 | GO:0035048 | splicing factor protein import into nucleus(GO:0035048) |
| 0.7 | 2.7 | GO:1903803 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 0.7 | 2.0 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 0.7 | 9.2 | GO:0035581 | sequestering of extracellular ligand from receptor(GO:0035581) |
| 0.6 | 7.1 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.6 | 6.4 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.6 | 1.3 | GO:0035511 | oxidative DNA demethylation(GO:0035511) |
| 0.6 | 17.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.6 | 3.8 | GO:1990668 | vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668) |
| 0.6 | 2.5 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.6 | 77.1 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.6 | 6.1 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.6 | 13.4 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.6 | 9.1 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.6 | 3.6 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 0.6 | 8.4 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.6 | 3.6 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.6 | 8.2 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.6 | 0.6 | GO:1900127 | positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 0.6 | 6.3 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 0.6 | 6.3 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 0.6 | 13.6 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
| 0.6 | 4.0 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.6 | 2.2 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 0.6 | 2.8 | GO:0070383 | DNA cytosine deamination(GO:0070383) |
| 0.6 | 3.3 | GO:0006196 | AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086) |
| 0.5 | 10.9 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.5 | 1.6 | GO:0090135 | actin filament branching(GO:0090135) |
| 0.5 | 1.6 | GO:0071934 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 0.5 | 4.3 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
| 0.5 | 11.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.5 | 2.7 | GO:0001315 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 0.5 | 22.3 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 0.5 | 7.4 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.5 | 2.1 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 0.5 | 3.1 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.5 | 6.2 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.5 | 3.6 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
| 0.5 | 3.1 | GO:0032916 | negative regulation of cardiac muscle adaptation(GO:0010616) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243) |
| 0.5 | 18.9 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.5 | 1.5 | GO:0019836 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 0.5 | 3.0 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.5 | 2.0 | GO:0070460 | thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612) |
| 0.5 | 9.0 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.5 | 1.5 | GO:1901355 | response to rapamycin(GO:1901355) |
| 0.5 | 15.9 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.5 | 1.4 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.5 | 9.6 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 0.5 | 1.4 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.5 | 2.8 | GO:1904688 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.5 | 18.3 | GO:0014904 | myotube cell development(GO:0014904) |
| 0.5 | 4.7 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.5 | 11.6 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 0.5 | 4.2 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.5 | 8.4 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.5 | 9.2 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.5 | 5.1 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.5 | 5.0 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.5 | 2.7 | GO:0001302 | replicative cell aging(GO:0001302) |
| 0.4 | 25.1 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.4 | 0.9 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
| 0.4 | 4.3 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.4 | 6.3 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.4 | 3.0 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 0.4 | 1.3 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 0.4 | 7.5 | GO:2000484 | positive regulation of interleukin-8 secretion(GO:2000484) |
| 0.4 | 2.1 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.4 | 20.6 | GO:0032873 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
| 0.4 | 10.4 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.4 | 1.2 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.4 | 5.2 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.4 | 4.3 | GO:0030656 | regulation of vitamin metabolic process(GO:0030656) |
| 0.4 | 2.7 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 0.4 | 7.5 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.4 | 1.5 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.4 | 3.3 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.4 | 2.2 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.4 | 22.6 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.4 | 5.1 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.4 | 1.4 | GO:0018032 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 0.4 | 2.5 | GO:0072599 | protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599) |
| 0.4 | 1.8 | GO:0032071 | regulation of endodeoxyribonuclease activity(GO:0032071) |
| 0.4 | 3.2 | GO:0046070 | dGTP metabolic process(GO:0046070) |
| 0.3 | 5.2 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.3 | 2.1 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.3 | 4.1 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.3 | 4.1 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.3 | 2.4 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 0.3 | 2.7 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.3 | 6.2 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.3 | 7.8 | GO:2000637 | positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637) |
| 0.3 | 7.0 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.3 | 2.9 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.3 | 2.6 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.3 | 3.5 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
| 0.3 | 3.1 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 0.3 | 0.6 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 0.3 | 1.2 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.3 | 2.1 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.3 | 5.9 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.3 | 0.9 | GO:1903717 | carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718) |
| 0.3 | 10.9 | GO:0006414 | translational elongation(GO:0006414) |
| 0.3 | 9.3 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.3 | 0.8 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 0.3 | 0.8 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.3 | 3.1 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.3 | 3.0 | GO:1900378 | positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378) |
| 0.3 | 1.4 | GO:0046532 | regulation of photoreceptor cell differentiation(GO:0046532) |
| 0.3 | 12.6 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.3 | 3.8 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.3 | 1.9 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.3 | 2.7 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
| 0.3 | 0.3 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.3 | 1.6 | GO:0042996 | regulation of Golgi to plasma membrane protein transport(GO:0042996) |
| 0.3 | 4.0 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.3 | 2.1 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.3 | 2.3 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.3 | 1.8 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.3 | 4.5 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.2 | 9.4 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.2 | 11.6 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.2 | 6.3 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.2 | 2.6 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
| 0.2 | 2.1 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.2 | 3.7 | GO:0035898 | parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
| 0.2 | 1.4 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.2 | 7.9 | GO:0060964 | regulation of posttranscriptional gene silencing(GO:0060147) regulation of gene silencing by miRNA(GO:0060964) regulation of gene silencing by RNA(GO:0060966) |
| 0.2 | 6.9 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.2 | 2.2 | GO:0060287 | epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) |
| 0.2 | 0.9 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.2 | 4.7 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.2 | 6.4 | GO:0034142 | toll-like receptor 4 signaling pathway(GO:0034142) |
| 0.2 | 0.9 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.2 | 7.2 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.2 | 2.0 | GO:1904996 | positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
| 0.2 | 3.2 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 0.2 | 1.9 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.2 | 0.8 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) dorsal/ventral axon guidance(GO:0033563) |
| 0.2 | 7.4 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.2 | 1.0 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.2 | 4.3 | GO:0009070 | serine family amino acid biosynthetic process(GO:0009070) |
| 0.2 | 2.0 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.2 | 2.5 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.2 | 5.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.2 | 5.4 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.2 | 8.3 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.2 | 0.4 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.2 | 2.8 | GO:0010566 | regulation of ketone biosynthetic process(GO:0010566) |
| 0.2 | 3.4 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.2 | 3.5 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.2 | 0.5 | GO:1903565 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 0.2 | 1.4 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.2 | 2.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.2 | 0.7 | GO:0039650 | modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148) |
| 0.2 | 1.0 | GO:0052805 | histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805) |
| 0.2 | 3.8 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.2 | 0.2 | GO:1904640 | response to methionine(GO:1904640) |
| 0.2 | 1.3 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.2 | 1.3 | GO:0071313 | cellular response to caffeine(GO:0071313) |
| 0.2 | 1.4 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.2 | 0.3 | GO:0060352 | cell adhesion molecule production(GO:0060352) |
| 0.2 | 1.2 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.1 | 12.4 | GO:0051289 | protein homotetramerization(GO:0051289) |
| 0.1 | 12.3 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.1 | 0.3 | GO:0046087 | cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) |
| 0.1 | 14.7 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.1 | 4.8 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 2.7 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
| 0.1 | 2.0 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.1 | 17.6 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.1 | 9.6 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.1 | 0.8 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.1 | 1.7 | GO:0031440 | regulation of mRNA 3'-end processing(GO:0031440) |
| 0.1 | 0.7 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 1.2 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.1 | 3.2 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.1 | 12.9 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
| 0.1 | 5.4 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.1 | 6.0 | GO:0031529 | ruffle organization(GO:0031529) |
| 0.1 | 0.9 | GO:0032099 | negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099) |
| 0.1 | 7.7 | GO:0070671 | interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349) |
| 0.1 | 0.6 | GO:0015692 | lead ion transport(GO:0015692) |
| 0.1 | 1.2 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.1 | 1.3 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.1 | 1.4 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.1 | 0.5 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 5.6 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.1 | 1.1 | GO:0033014 | porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014) |
| 0.1 | 13.5 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.1 | 0.8 | GO:0015871 | choline transport(GO:0015871) |
| 0.1 | 3.6 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.1 | 2.0 | GO:0002260 | lymphocyte homeostasis(GO:0002260) |
| 0.1 | 2.1 | GO:1902603 | carnitine transmembrane transport(GO:1902603) |
| 0.1 | 0.7 | GO:1905123 | regulation of glucosylceramidase activity(GO:1905123) |
| 0.1 | 4.4 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.1 | 5.4 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.1 | 3.5 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.1 | 2.1 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
| 0.1 | 1.9 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.1 | 1.3 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.1 | 3.8 | GO:0008347 | glial cell migration(GO:0008347) |
| 0.1 | 2.8 | GO:0021795 | cerebral cortex cell migration(GO:0021795) |
| 0.1 | 18.7 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.1 | 0.8 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 0.1 | 1.0 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 0.1 | 0.7 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.1 | 1.5 | GO:0060512 | prostate gland morphogenesis(GO:0060512) |
| 0.1 | 1.9 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.1 | 2.3 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.1 | 0.2 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 0.1 | 0.7 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 2.7 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 0.1 | 0.8 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.1 | 2.9 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 1.6 | GO:0030728 | ovulation(GO:0030728) |
| 0.1 | 4.0 | GO:0051452 | intracellular pH reduction(GO:0051452) |
| 0.1 | 5.3 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
| 0.1 | 1.0 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.1 | 0.6 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.1 | 1.0 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.1 | 0.8 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.1 | 0.8 | GO:0044065 | regulation of respiratory system process(GO:0044065) |
| 0.1 | 1.7 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.1 | 1.1 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.1 | 2.7 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.1 | 1.4 | GO:1901687 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.1 | 6.3 | GO:1901796 | regulation of signal transduction by p53 class mediator(GO:1901796) |
| 0.1 | 1.0 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.1 | 0.4 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.1 | 0.9 | GO:0042761 | fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 0.1 | 3.7 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.1 | 0.7 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
| 0.0 | 0.9 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 3.2 | GO:0021987 | cerebral cortex development(GO:0021987) |
| 0.0 | 0.4 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.0 | 2.0 | GO:0048477 | oogenesis(GO:0048477) |
| 0.0 | 4.3 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 15.0 | GO:0006397 | mRNA processing(GO:0006397) |
| 0.0 | 1.8 | GO:0001707 | mesoderm formation(GO:0001707) |
| 0.0 | 2.2 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 0.2 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 1.1 | GO:0045652 | regulation of megakaryocyte differentiation(GO:0045652) |
| 0.0 | 0.7 | GO:0045143 | homologous chromosome segregation(GO:0045143) |
| 0.0 | 2.3 | GO:0051149 | positive regulation of muscle cell differentiation(GO:0051149) |
| 0.0 | 0.3 | GO:0002475 | antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.0 | 0.4 | GO:0006293 | nucleotide-excision repair, preincision complex stabilization(GO:0006293) |
| 0.0 | 0.2 | GO:0045617 | positive regulation of keratinocyte proliferation(GO:0010838) negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.0 | 0.4 | GO:0001946 | lymphangiogenesis(GO:0001946) |
| 0.0 | 0.1 | GO:0070989 | oxidative demethylation(GO:0070989) |
| 0.0 | 1.2 | GO:0032481 | positive regulation of type I interferon production(GO:0032481) |
| 0.0 | 0.1 | GO:0038043 | interleukin-5-mediated signaling pathway(GO:0038043) |
| 0.0 | 0.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 1.0 | GO:0071158 | positive regulation of cell cycle arrest(GO:0071158) |
| 0.0 | 0.5 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.0 | 0.8 | GO:0050766 | positive regulation of phagocytosis(GO:0050766) |
| 0.0 | 0.4 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.2 | GO:0036315 | cellular response to sterol(GO:0036315) |
| 0.0 | 2.3 | GO:0038095 | Fc-epsilon receptor signaling pathway(GO:0038095) |
| 0.0 | 0.4 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
| 0.0 | 0.3 | GO:0071711 | basement membrane organization(GO:0071711) |
| 0.0 | 0.6 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.5 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.0 | 0.9 | GO:0043647 | inositol phosphate metabolic process(GO:0043647) |
| 0.0 | 0.3 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.0 | 0.0 | GO:0060842 | blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842) |
| 0.0 | 0.5 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 0.1 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.0 | 0.3 | GO:0016574 | histone ubiquitination(GO:0016574) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.2 | 43.0 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 6.5 | 26.1 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 4.8 | 33.5 | GO:0005683 | U7 snRNP(GO:0005683) |
| 4.5 | 22.6 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 4.4 | 17.7 | GO:0071986 | Ragulator complex(GO:0071986) |
| 4.1 | 45.3 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 3.9 | 50.4 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 3.8 | 11.5 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 3.7 | 11.2 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 3.7 | 33.0 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 3.5 | 21.3 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 3.5 | 10.5 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 3.4 | 27.0 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 3.1 | 21.6 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 3.1 | 9.2 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 3.0 | 21.1 | GO:0000243 | commitment complex(GO:0000243) |
| 2.8 | 11.4 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 2.7 | 8.2 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 2.6 | 10.5 | GO:1990423 | RZZ complex(GO:1990423) |
| 2.6 | 33.9 | GO:0005688 | U6 snRNP(GO:0005688) |
| 2.6 | 10.3 | GO:0035363 | histone locus body(GO:0035363) |
| 2.6 | 23.1 | GO:0034709 | methylosome(GO:0034709) |
| 2.5 | 17.5 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 2.4 | 24.3 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 2.4 | 28.5 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 2.3 | 47.6 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 2.2 | 11.1 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 2.2 | 6.7 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 2.2 | 8.7 | GO:0071920 | cleavage body(GO:0071920) |
| 2.1 | 18.9 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 2.0 | 9.9 | GO:0005749 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 1.9 | 11.6 | GO:0061617 | MICOS complex(GO:0061617) |
| 1.9 | 5.6 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 1.9 | 13.1 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 1.9 | 7.5 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 1.9 | 5.6 | GO:0044393 | microspike(GO:0044393) |
| 1.7 | 13.5 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 1.6 | 4.9 | GO:0034455 | t-UTP complex(GO:0034455) |
| 1.6 | 9.5 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 1.6 | 113.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 1.5 | 39.4 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 1.5 | 6.0 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 1.5 | 5.9 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 1.4 | 16.4 | GO:0071203 | WASH complex(GO:0071203) |
| 1.4 | 23.2 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 1.4 | 5.4 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 1.3 | 28.1 | GO:0097342 | ripoptosome(GO:0097342) |
| 1.3 | 5.3 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 1.3 | 5.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 1.3 | 25.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 1.3 | 6.3 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 1.2 | 9.8 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 1.2 | 15.7 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 1.2 | 6.0 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 1.1 | 5.6 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 1.1 | 11.1 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 1.1 | 8.9 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 1.1 | 12.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 1.1 | 9.8 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 1.1 | 8.7 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 1.1 | 12.9 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 1.1 | 9.6 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 1.1 | 7.4 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 1.1 | 8.5 | GO:0008274 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 1.0 | 9.4 | GO:0032133 | chromosome passenger complex(GO:0032133) meiotic spindle(GO:0072687) |
| 1.0 | 6.2 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 1.0 | 5.2 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 1.0 | 9.2 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 1.0 | 5.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 1.0 | 12.8 | GO:0042555 | MCM complex(GO:0042555) |
| 1.0 | 18.2 | GO:0043219 | lateral loop(GO:0043219) |
| 1.0 | 12.4 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.9 | 11.0 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.9 | 14.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.9 | 5.3 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.8 | 5.1 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.8 | 8.4 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.8 | 9.2 | GO:0032039 | integrator complex(GO:0032039) |
| 0.8 | 28.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.8 | 3.2 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.8 | 3.2 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.8 | 2.4 | GO:1990913 | sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917) |
| 0.8 | 2.3 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.8 | 10.9 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.8 | 1.6 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.8 | 2.3 | GO:0033593 | BRCA2-MAGE-D1 complex(GO:0033593) |
| 0.8 | 6.8 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.7 | 2.9 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.7 | 2.8 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 0.7 | 4.9 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.7 | 3.4 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.7 | 1.3 | GO:0055087 | Ski complex(GO:0055087) |
| 0.7 | 17.7 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.6 | 33.1 | GO:0097525 | spliceosomal snRNP complex(GO:0097525) |
| 0.6 | 8.2 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.6 | 5.0 | GO:0070522 | nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522) |
| 0.6 | 4.3 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 0.6 | 5.4 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.6 | 5.9 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.6 | 2.3 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.6 | 2.8 | GO:0045293 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.6 | 58.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.6 | 17.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.6 | 6.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.5 | 27.5 | GO:0005844 | polysome(GO:0005844) |
| 0.5 | 5.9 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.5 | 2.1 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.5 | 4.7 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.5 | 5.7 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.5 | 45.6 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.5 | 4.0 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.5 | 18.9 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.5 | 12.5 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.5 | 6.2 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.5 | 2.4 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.5 | 2.8 | GO:0030681 | multimeric ribonuclease P complex(GO:0030681) |
| 0.5 | 18.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.4 | 1.3 | GO:0033167 | ARC complex(GO:0033167) |
| 0.4 | 9.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.4 | 7.5 | GO:0008091 | spectrin(GO:0008091) |
| 0.4 | 3.1 | GO:0030891 | VCB complex(GO:0030891) |
| 0.4 | 7.4 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.4 | 8.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.4 | 6.7 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.4 | 3.1 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 0.4 | 7.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.4 | 7.9 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.4 | 3.7 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.4 | 4.6 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.3 | 1.7 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.3 | 3.1 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.3 | 7.0 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.3 | 8.9 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.3 | 2.5 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.3 | 18.6 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.3 | 5.2 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.3 | 2.7 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.3 | 40.6 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.3 | 0.9 | GO:0031085 | BLOC-3 complex(GO:0031085) |
| 0.3 | 2.5 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.3 | 4.2 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.3 | 3.0 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.3 | 6.5 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.3 | 3.7 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.3 | 33.7 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.3 | 3.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.2 | 14.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.2 | 1.2 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.2 | 12.2 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.2 | 9.3 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.2 | 1.6 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.2 | 12.3 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.2 | 9.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.2 | 3.9 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.2 | 1.5 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.2 | 11.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.2 | 19.5 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.2 | 8.3 | GO:0016592 | mediator complex(GO:0016592) |
| 0.2 | 18.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.2 | 20.0 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.2 | 14.1 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.2 | 6.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.2 | 7.6 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.2 | 1.1 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.2 | 2.7 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.2 | 7.8 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.2 | 9.3 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.2 | 40.2 | GO:0005819 | spindle(GO:0005819) |
| 0.2 | 7.0 | GO:0002102 | podosome(GO:0002102) |
| 0.2 | 2.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.2 | 19.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.2 | 0.8 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 0.2 | 8.1 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.2 | 9.7 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 2.1 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 14.8 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.1 | 3.9 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 3.8 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 0.8 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.1 | 0.4 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 5.2 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.1 | 7.6 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 2.5 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.6 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 2.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 45.6 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 3.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 7.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 2.1 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 0.2 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.1 | 1.7 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.1 | 5.6 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 0.8 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.1 | 1.0 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 2.9 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 1.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 2.0 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 8.8 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 5.4 | GO:0005776 | autophagosome(GO:0005776) |
| 0.1 | 0.9 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.1 | 2.4 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 3.1 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.1 | 4.3 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 0.4 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 0.2 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 0.5 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 4.1 | GO:0044853 | plasma membrane raft(GO:0044853) |
| 0.0 | 1.2 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.1 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.0 | 0.4 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 4.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 5.2 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 1.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 0.2 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 7.8 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 6.9 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 4.0 | GO:0000785 | chromatin(GO:0000785) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.9 | 17.6 | GO:0045550 | geranylgeranyl reductase activity(GO:0045550) |
| 5.2 | 15.6 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 5.1 | 15.2 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 4.9 | 19.6 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 4.8 | 14.3 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 4.3 | 12.9 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 4.2 | 12.7 | GO:0000035 | acyl binding(GO:0000035) |
| 3.9 | 23.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 3.9 | 11.6 | GO:0033989 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594) |
| 3.9 | 23.1 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 3.7 | 15.0 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 3.5 | 21.1 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 3.5 | 10.5 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 2.8 | 8.4 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 2.7 | 13.6 | GO:0004161 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 2.7 | 8.1 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 2.7 | 24.3 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 2.7 | 18.9 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 2.6 | 18.4 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 2.6 | 13.1 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 2.5 | 9.9 | GO:0051538 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 2.2 | 8.7 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 2.1 | 6.3 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 2.1 | 8.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 2.1 | 6.3 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 2.0 | 14.1 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 2.0 | 6.0 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 2.0 | 5.9 | GO:0043035 | chromatin insulator sequence binding(GO:0043035) |
| 1.9 | 5.6 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 1.9 | 16.7 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 1.8 | 5.5 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
| 1.8 | 7.3 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 1.8 | 7.2 | GO:0003990 | acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265) |
| 1.8 | 5.4 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 1.8 | 17.9 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 1.8 | 12.4 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 1.8 | 12.4 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 1.7 | 8.7 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 1.7 | 8.7 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 1.7 | 7.0 | GO:0032551 | pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 1.7 | 10.1 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 1.7 | 13.2 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 1.6 | 9.8 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 1.6 | 31.0 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 1.5 | 6.2 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 1.5 | 46.2 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 1.5 | 6.1 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 1.5 | 13.5 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 1.5 | 9.0 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 1.5 | 7.4 | GO:0016936 | galactoside binding(GO:0016936) |
| 1.5 | 34.1 | GO:0035173 | histone kinase activity(GO:0035173) |
| 1.5 | 28.2 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 1.5 | 4.4 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 1.5 | 11.7 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 1.5 | 11.7 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 1.4 | 11.5 | GO:0034603 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 1.4 | 10.1 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 1.4 | 2.8 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 1.4 | 2.8 | GO:0008969 | phosphohistidine phosphatase activity(GO:0008969) |
| 1.4 | 12.3 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 1.3 | 4.0 | GO:0047115 | phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115) |
| 1.3 | 6.7 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 1.3 | 4.0 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 1.3 | 50.0 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 1.3 | 23.2 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 1.3 | 3.8 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 1.3 | 37.9 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 1.2 | 46.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 1.2 | 6.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 1.2 | 3.6 | GO:0052852 | (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854) |
| 1.2 | 9.6 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 1.2 | 3.5 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 1.2 | 14.0 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 1.1 | 10.0 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 1.1 | 3.2 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 1.1 | 3.2 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 1.1 | 4.3 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 1.1 | 3.2 | GO:0004056 | argininosuccinate lyase activity(GO:0004056) |
| 1.1 | 12.8 | GO:0015266 | protein channel activity(GO:0015266) |
| 1.1 | 3.2 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 1.1 | 9.5 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 1.0 | 4.2 | GO:0047676 | arachidonate-CoA ligase activity(GO:0047676) |
| 1.0 | 32.0 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 1.0 | 5.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 1.0 | 15.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 1.0 | 5.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 1.0 | 5.0 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 1.0 | 4.9 | GO:0047280 | nicotinamide phosphoribosyltransferase activity(GO:0047280) |
| 1.0 | 1.0 | GO:0047023 | androsterone dehydrogenase activity(GO:0047023) |
| 1.0 | 5.7 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.9 | 10.4 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.9 | 6.6 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.9 | 2.8 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
| 0.9 | 7.5 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.9 | 63.3 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.9 | 11.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.9 | 2.7 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.9 | 2.7 | GO:0004608 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.9 | 12.4 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
| 0.8 | 178.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.8 | 4.2 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.8 | 9.8 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.8 | 16.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.8 | 11.0 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.8 | 3.1 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.8 | 4.7 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.8 | 20.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.8 | 3.9 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.8 | 3.0 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.8 | 3.8 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.7 | 17.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.7 | 1.5 | GO:0034040 | lipid-transporting ATPase activity(GO:0034040) |
| 0.7 | 4.4 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.7 | 7.2 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 0.7 | 8.3 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 0.7 | 24.0 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.7 | 22.8 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.7 | 67.7 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.7 | 5.9 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.7 | 7.9 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.7 | 3.9 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.6 | 21.2 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.6 | 6.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.6 | 5.0 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.6 | 3.1 | GO:0004447 | iodide peroxidase activity(GO:0004447) |
| 0.6 | 4.7 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.6 | 11.7 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.6 | 7.5 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.6 | 15.5 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.6 | 16.1 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.6 | 2.2 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.6 | 2.8 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 0.5 | 9.8 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.5 | 1.6 | GO:0015403 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.5 | 67.1 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.5 | 4.2 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.5 | 2.1 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.5 | 3.1 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.5 | 2.5 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.5 | 7.6 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.5 | 9.8 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.5 | 12.6 | GO:0001848 | complement binding(GO:0001848) |
| 0.5 | 1.9 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.5 | 1.9 | GO:0046573 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 0.5 | 6.6 | GO:0050542 | icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
| 0.5 | 8.5 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.4 | 4.9 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.4 | 7.9 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.4 | 9.5 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 0.4 | 1.7 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.4 | 6.4 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.4 | 1.2 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.4 | 4.3 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.4 | 3.1 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 0.4 | 2.6 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.4 | 0.4 | GO:0016508 | long-chain-enoyl-CoA hydratase activity(GO:0016508) |
| 0.4 | 1.4 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.4 | 2.5 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.3 | 6.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.3 | 19.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.3 | 7.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.3 | 4.7 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.3 | 2.7 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.3 | 4.4 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.3 | 2.7 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.3 | 9.6 | GO:0005521 | lamin binding(GO:0005521) |
| 0.3 | 2.7 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.3 | 2.7 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.3 | 2.6 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.3 | 2.0 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.3 | 2.9 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.3 | 1.3 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.3 | 8.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.3 | 9.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.3 | 12.8 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.3 | 0.3 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.3 | 29.1 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.3 | 0.9 | GO:0080023 | 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023) |
| 0.3 | 6.9 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.3 | 2.1 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.3 | 4.8 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.3 | 0.9 | GO:0052871 | tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 0.3 | 4.3 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.3 | 116.0 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.3 | 7.1 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.3 | 0.8 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.3 | 3.7 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.3 | 0.8 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.3 | 1.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.3 | 2.7 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.3 | 1.3 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 0.3 | 0.8 | GO:0032181 | double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide insertion or deletion binding(GO:0032139) dinucleotide repeat insertion binding(GO:0032181) |
| 0.3 | 1.8 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.3 | 2.0 | GO:0004996 | thyroid-stimulating hormone receptor activity(GO:0004996) |
| 0.2 | 3.7 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.2 | 4.6 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.2 | 1.4 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.2 | 1.9 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.2 | 3.6 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.2 | 3.3 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.2 | 1.2 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.2 | 2.1 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.2 | 3.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.2 | 6.6 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.2 | 2.1 | GO:0016004 | phospholipase activator activity(GO:0016004) |
| 0.2 | 4.2 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.2 | 5.1 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.2 | 1.9 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.2 | 3.0 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.2 | 6.6 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.2 | 1.3 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.2 | 27.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.2 | 3.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.2 | 18.5 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.2 | 2.4 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.2 | 2.4 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.2 | 3.5 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.2 | 6.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.2 | 0.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.2 | 3.7 | GO:0051430 | mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.2 | 9.9 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 2.1 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 8.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 2.6 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 22.2 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 2.8 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 1.9 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 7.1 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.1 | 5.4 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.1 | 0.4 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.1 | 0.8 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.1 | 1.5 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 0.6 | GO:0015087 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.1 | 71.5 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.1 | 0.8 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 2.0 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.1 | 1.7 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 1.0 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 0.1 | 0.3 | GO:0015226 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
| 0.1 | 0.6 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.1 | 22.7 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.1 | 5.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 9.1 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 0.9 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.1 | 1.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 3.5 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.1 | 2.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 1.6 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
| 0.1 | 0.5 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.1 | 15.8 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.1 | 2.5 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 0.1 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.1 | 0.3 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.1 | 1.1 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 0.7 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 1.2 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.1 | 0.6 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 5.3 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.1 | 0.9 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 0.2 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 1.1 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.1 | 1.0 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.1 | 2.5 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
| 0.1 | 2.8 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 0.7 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 2.9 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 2.8 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.1 | 0.2 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.1 | 1.4 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 0.2 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.1 | 2.8 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.1 | 0.5 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.0 | 0.8 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 2.1 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.2 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.0 | 0.7 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 1.8 | GO:0042379 | chemokine receptor binding(GO:0042379) |
| 0.0 | 0.9 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.3 | GO:0030882 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
| 0.0 | 0.4 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 1.3 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.0 | 1.0 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.0 | 0.1 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.0 | 1.3 | GO:0050136 | NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.1 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
| 0.0 | 0.8 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.0 | 0.6 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.1 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.4 | GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 1.3 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.4 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.0 | 1.5 | GO:0019838 | growth factor binding(GO:0019838) |
| 0.0 | 0.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.4 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 49.3 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 1.2 | 45.3 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.9 | 17.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.9 | 28.1 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.9 | 52.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.8 | 47.9 | PID ATR PATHWAY | ATR signaling pathway |
| 0.6 | 7.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.6 | 36.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.5 | 17.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.5 | 26.0 | PID MYC PATHWAY | C-MYC pathway |
| 0.5 | 8.7 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.5 | 11.7 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.5 | 19.4 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.4 | 7.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.4 | 4.5 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.4 | 12.1 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.4 | 16.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.4 | 15.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.3 | 10.6 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.3 | 1.2 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.3 | 8.2 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.3 | 54.5 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.3 | 5.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.3 | 9.4 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.3 | 1.3 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.3 | 17.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.3 | 12.7 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.3 | 18.6 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.2 | 17.9 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.2 | 12.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.2 | 22.7 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.2 | 2.2 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.2 | 1.5 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.2 | 2.1 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.2 | 4.2 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.2 | 2.7 | PID FOXO PATHWAY | FoxO family signaling |
| 0.2 | 9.4 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.2 | 2.0 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.2 | 9.9 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.2 | 10.2 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.2 | 3.5 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.2 | 13.5 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.2 | 8.0 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.1 | 10.4 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 2.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 5.4 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 2.7 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 5.1 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 6.0 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 2.0 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.1 | 1.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 5.6 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 3.1 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 2.4 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.1 | 0.8 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.1 | 1.4 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.0 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 2.6 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 2.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.8 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 2.2 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.9 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 1.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.5 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.4 | PID TNF PATHWAY | TNF receptor signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 32.8 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 2.4 | 36.3 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 2.3 | 67.8 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 1.9 | 44.6 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 1.7 | 53.3 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 1.6 | 30.1 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 1.3 | 45.6 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 1.3 | 97.3 | REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | Genes involved in Assembly of the pre-replicative complex |
| 1.3 | 15.8 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 1.3 | 72.2 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 1.2 | 18.3 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 1.2 | 35.7 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 1.2 | 18.9 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 1.1 | 28.1 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 1.1 | 24.6 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 1.1 | 23.2 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 1.0 | 61.9 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 1.0 | 74.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.9 | 11.3 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.9 | 75.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.9 | 28.1 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.9 | 13.7 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.9 | 6.0 | REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
| 0.8 | 11.6 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.8 | 15.4 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.7 | 20.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.7 | 16.2 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 0.6 | 12.9 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.6 | 11.6 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.6 | 65.1 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.6 | 20.5 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.6 | 18.9 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.6 | 8.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.6 | 47.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.6 | 13.5 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.5 | 18.6 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.5 | 5.7 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.5 | 23.4 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.5 | 6.3 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.5 | 8.8 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.5 | 50.9 | REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
| 0.5 | 8.2 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.4 | 11.2 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.4 | 11.6 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.4 | 7.3 | REACTOME DEADENYLATION DEPENDENT MRNA DECAY | Genes involved in Deadenylation-dependent mRNA decay |
| 0.4 | 7.5 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.4 | 13.3 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.4 | 3.7 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.4 | 8.0 | REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| 0.4 | 6.3 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.4 | 11.7 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.4 | 15.6 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.4 | 8.9 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.4 | 5.6 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.4 | 12.0 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.3 | 12.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.3 | 4.3 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.3 | 8.1 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.3 | 6.4 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.3 | 10.8 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.3 | 7.6 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.3 | 5.0 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.3 | 28.2 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.3 | 4.7 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.3 | 4.4 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.3 | 7.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.3 | 5.5 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.3 | 5.9 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.2 | 4.9 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.2 | 6.8 | REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | Genes involved in Glucagon signaling in metabolic regulation |
| 0.2 | 7.9 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.2 | 6.2 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.2 | 2.7 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.2 | 5.1 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.2 | 9.7 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.2 | 5.1 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.2 | 8.8 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.2 | 3.5 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.2 | 5.7 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.2 | 9.5 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.2 | 5.6 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.2 | 4.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 3.5 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.2 | 9.4 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.2 | 5.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.2 | 1.3 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.2 | 2.3 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.2 | 1.3 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 3.2 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 0.1 | 1.7 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.1 | 3.4 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 1.2 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 0.9 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 4.8 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 5.2 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 8.5 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 2.8 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.1 | 3.1 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 1.8 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 0.8 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.1 | 0.7 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 2.4 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 0.8 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.1 | 5.9 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 1.9 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.1 | 1.3 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 4.8 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 8.6 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.9 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 0.6 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 1.5 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 0.5 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.4 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.3 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 0.4 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.2 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 1.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 1.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |