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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HSF4

Z-value: 2.21

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Transcription factors associated with HSF4

Gene Symbol Gene ID Gene Info
HSF4
ENSG00000102878.18 HSF4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF4hg38_v1_chr16_+_67164730_67164768-0.685.3e-31Click!

Activity profile of HSF4 motif

Sorted Z-values of HSF4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_+_56051685 94.07 ENST00000335503.3
CCT6A
chaperonin containing TCP1 subunit 6A
chr7_+_56051756 82.29 ENST00000275603.9
CCT6A
chaperonin containing TCP1 subunit 6A
chr17_-_42016680 78.89 ENST00000674497.1
DNAJC7
DnaJ heat shock protein family (Hsp40) member C7
chr11_+_64186219 69.10 ENST00000543847.1
STIP1
stress induced phosphoprotein 1
chr9_+_33025265 60.79 ENST00000330899.5
DNAJA1
DnaJ heat shock protein family (Hsp40) member A1
chr13_-_31161927 58.69 ENST00000380405.7
HSPH1
heat shock protein family H (Hsp110) member 1
chr14_-_102087034 58.03 ENST00000216281.13
ENST00000553585.5
HSP90AA1
heat shock protein 90 alpha family class A member 1
chr11_-_123062335 55.40 ENST00000453788.6
ENST00000527387.5
HSPA8
heat shock protein family A (Hsp70) member 8
chr11_-_123062022 54.11 ENST00000532182.5
ENST00000524590.5
ENST00000528292.5
ENST00000533540.5
ENST00000534624.6
ENST00000525463.5
HSPA8
heat shock protein family A (Hsp70) member 8
chr12_+_2794961 52.75 ENST00000001008.6
FKBP4
FKBP prolyl isomerase 4
chr9_-_86100123 52.24 ENST00000388711.7
ENST00000466178.1
GOLM1
golgi membrane protein 1
chr2_+_200306048 51.23 ENST00000409988.7
ENST00000409385.5
SPATS2L
spermatogenesis associated serine rich 2 like
chr11_+_64186163 50.88 ENST00000305218.9
ENST00000538945.5
STIP1
stress induced phosphoprotein 1
chr2_+_200306519 48.87 ENST00000360760.9
SPATS2L
spermatogenesis associated serine rich 2 like
chrX_-_103688033 48.78 ENST00000434230.5
ENST00000418819.5
ENST00000360458.5
MORF4L2
mortality factor 4 like 2
chrX_-_103688090 47.20 ENST00000433176.6
MORF4L2
mortality factor 4 like 2
chr13_-_31161890 46.61 ENST00000320027.10
HSPH1
heat shock protein family H (Hsp110) member 1
chr21_-_29073565 46.59 ENST00000431234.1
ENST00000286788.9
ENST00000540844.5
CCT8
chaperonin containing TCP1 subunit 8
chr1_-_45521854 45.11 ENST00000372079.1
ENST00000319248.13
PRDX1
peroxiredoxin 1
chr2_-_61888570 43.34 ENST00000394440.8
ENST00000544079.2
CCT4
chaperonin containing TCP1 subunit 4
chr1_+_154974672 41.83 ENST00000308987.6
ENST00000368436.1
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr1_-_45521931 41.72 ENST00000447184.6
ENST00000262746.5
PRDX1
peroxiredoxin 1
chr13_-_31162341 41.49 ENST00000445273.6
ENST00000630972.2
HSPH1
heat shock protein family H (Hsp110) member 1
chr6_+_44246166 39.02 ENST00000620073.4
HSP90AB1
heat shock protein 90 alpha family class B member 1
chr9_-_83978429 38.94 ENST00000351839.7
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr9_-_86099506 37.40 ENST00000388712.7
GOLM1
golgi membrane protein 1
chr11_+_75562056 37.39 ENST00000533603.5
SERPINH1
serpin family H member 1
chr6_+_44247866 37.07 ENST00000371554.2
HSP90AB1
heat shock protein 90 alpha family class B member 1
chr11_+_75562242 37.07 ENST00000526397.5
ENST00000529643.1
ENST00000525492.5
ENST00000530284.5
ENST00000358171.8
SERPINH1
serpin family H member 1
chr1_+_154974653 36.23 ENST00000368439.5
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr2_-_69437588 36.04 ENST00000394305.5
NFU1
NFU1 iron-sulfur cluster scaffold
chr12_+_103930600 35.89 ENST00000680316.1
ENST00000679861.1
HSP90B1
heat shock protein 90 beta family member 1
chr2_+_197500398 35.28 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr1_-_244863085 35.22 ENST00000440865.2
HNRNPU
heterogeneous nuclear ribonucleoprotein U
chr11_-_83285965 35.14 ENST00000529073.5
ENST00000529611.5
CCDC90B
coiled-coil domain containing 90B
chr7_+_76303547 34.87 ENST00000429938.1
HSPB1
heat shock protein family B (small) member 1
chr12_-_110445540 34.02 ENST00000547365.1
ARPC3
actin related protein 2/3 complex subunit 3
chr4_-_17512079 33.96 ENST00000428702.6
ENST00000508623.5
ENST00000513615.5
ENST00000281243.10
QDPR
quinoid dihydropteridine reductase
chr11_+_66002754 33.92 ENST00000527348.1
BANF1
BAF nuclear assembly factor 1
chr11_-_83286328 33.10 ENST00000525503.5
CCDC90B
coiled-coil domain containing 90B
chr5_+_10250216 32.98 ENST00000515390.5
CCT5
chaperonin containing TCP1 subunit 5
chr11_+_66002225 32.97 ENST00000445560.6
ENST00000530204.1
BANF1
BAF nuclear assembly factor 1
chr12_+_103930332 32.95 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
HSP90B1
heat shock protein 90 beta family member 1
chr12_+_69585434 32.94 ENST00000299300.11
ENST00000544368.6
CCT2
chaperonin containing TCP1 subunit 2
chr9_-_33025052 32.90 ENST00000673248.1
APTX
aprataxin
chr2_-_197499826 32.82 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
HSPD1
heat shock protein family D (Hsp60) member 1
chr7_-_26200734 32.65 ENST00000354667.8
ENST00000618183.5
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr9_-_33025088 32.31 ENST00000436040.7
APTX
aprataxin
chr11_+_75562274 31.97 ENST00000532356.5
ENST00000524558.5
SERPINH1
serpin family H member 1
chr11_-_83286377 31.56 ENST00000455220.6
ENST00000529689.5
CCDC90B
coiled-coil domain containing 90B
chr7_+_76302665 31.53 ENST00000248553.7
ENST00000674638.1
ENST00000674547.1
ENST00000675226.1
ENST00000675538.1
ENST00000676231.1
ENST00000675134.1
ENST00000675906.1
ENST00000674650.1
HSPB1
heat shock protein family B (small) member 1
chr2_+_197500371 30.97 ENST00000409468.1
ENST00000233893.10
HSPE1
heat shock protein family E (Hsp10) member 1
chr2_-_197499857 30.21 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
HSPD1
heat shock protein family D (Hsp60) member 1
chrX_-_153724044 29.97 ENST00000423827.5
ENST00000458587.8
BCAP31
B cell receptor associated protein 31
chrX_-_153724343 29.94 ENST00000442093.5
ENST00000345046.12
ENST00000645377.1
ENST00000672675.1
ENST00000647529.1
ENST00000429550.5
BCAP31
B cell receptor associated protein 31
chr1_-_6393339 29.48 ENST00000608083.5
ACOT7
acyl-CoA thioesterase 7
chr5_+_10250272 29.45 ENST00000280326.9
ENST00000625723.1
CCT5
chaperonin containing TCP1 subunit 5
chr21_-_39349048 29.25 ENST00000380748.5
ENST00000380749.10
HMGN1
high mobility group nucleosome binding domain 1
chr11_+_66002475 29.24 ENST00000312175.7
ENST00000533166.5
BANF1
BAF nuclear assembly factor 1
chr1_-_6393750 29.21 ENST00000545482.5
ENST00000361521.9
ACOT7
acyl-CoA thioesterase 7
chr2_+_200306340 26.18 ENST00000451764.6
SPATS2L
spermatogenesis associated serine rich 2 like
chr22_-_40856565 25.43 ENST00000620312.4
ENST00000216218.8
ST13
ST13 Hsp70 interacting protein
chr7_-_56051544 25.27 ENST00000395471.7
PSPH
phosphoserine phosphatase
chr1_-_156338226 24.82 ENST00000496684.6
ENST00000368259.6
ENST00000472765.6
ENST00000295688.8
ENST00000533194.5
ENST00000478640.6
CCT3
chaperonin containing TCP1 subunit 3
chr1_+_26921715 24.29 ENST00000321265.10
NUDC
nuclear distribution C, dynein complex regulator
chr1_+_175000126 23.64 ENST00000406752.1
ENST00000405362.1
CACYBP
calcyclin binding protein
chr17_-_63773534 23.63 ENST00000403162.7
ENST00000582252.1
ENST00000225726.10
CCDC47
coiled-coil domain containing 47
chr4_-_158723355 23.61 ENST00000307720.4
PPID
peptidylprolyl isomerase D
chr3_+_159069252 23.08 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr16_-_8861713 22.63 ENST00000567554.5
CARHSP1
calcium regulated heat stable protein 1
chrX_+_123961304 22.62 ENST00000371160.5
ENST00000435103.5
STAG2
stromal antigen 2
chr1_-_6200831 22.55 ENST00000497965.5
RPL22
ribosomal protein L22
chr1_-_53238485 22.31 ENST00000371466.4
ENST00000371470.8
MAGOH
mago homolog, exon junction complex subunit
chr15_+_43800586 21.44 ENST00000442995.4
ENST00000458412.2
HYPK
huntingtin interacting protein K
chr11_+_20363685 21.44 ENST00000530266.5
ENST00000451739.7
ENST00000421577.6
ENST00000443524.6
ENST00000419348.6
HTATIP2
HIV-1 Tat interactive protein 2
chr13_-_30617500 21.01 ENST00000405805.5
HMGB1
high mobility group box 1
chr19_-_14518383 20.60 ENST00000254322.3
ENST00000595139.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr4_+_41256921 20.08 ENST00000284440.9
ENST00000508768.5
ENST00000512788.1
UCHL1
ubiquitin C-terminal hydrolase L1
chr15_+_96325935 19.41 ENST00000421109.6
NR2F2
nuclear receptor subfamily 2 group F member 2
chr16_-_8861799 19.02 ENST00000610831.4
ENST00000614449.4
CARHSP1
calcium regulated heat stable protein 1
chr20_+_19886506 18.91 ENST00000648440.1
RIN2
Ras and Rab interactor 2
chr3_-_185938006 18.83 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
TRA2B
transformer 2 beta homolog
chr14_-_23071617 17.41 ENST00000357481.6
ACIN1
apoptotic chromatin condensation inducer 1
chr10_-_73096850 17.03 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr9_-_6015607 16.06 ENST00000485372.1
ENST00000259569.6
ENST00000623170.1
RANBP6
RAN binding protein 6
chr14_-_23071538 15.90 ENST00000555566.1
ENST00000338631.10
ENST00000557515.5
ENST00000397341.7
ACIN1
apoptotic chromatin condensation inducer 1
chr11_-_90223059 15.59 ENST00000457199.6
ENST00000530765.5
CHORDC1
cysteine and histidine rich domain containing 1
chr11_+_86302211 15.57 ENST00000533986.5
ENST00000278483.8
HIKESHI
heat shock protein nuclear import factor hikeshi
chr11_-_90223036 15.30 ENST00000320585.11
CHORDC1
cysteine and histidine rich domain containing 1
chr16_-_8861744 15.21 ENST00000569398.5
ENST00000568968.1
CARHSP1
calcium regulated heat stable protein 1
chr11_+_10751203 15.16 ENST00000361367.7
CTR9
CTR9 homolog, Paf1/RNA polymerase II complex component
chr7_-_56051288 15.04 ENST00000419984.6
ENST00000413218.5
ENST00000275605.8
ENST00000424596.1
ENST00000421312.5
ENST00000416592.1
PSPH
phosphoserine phosphatase
chr19_-_14517425 13.86 ENST00000676577.1
ENST00000677204.1
ENST00000598235.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr20_+_4686320 13.75 ENST00000430350.2
PRNP
prion protein
chr4_+_41359599 13.25 ENST00000513024.5
LIMCH1
LIM and calponin homology domains 1
chr19_+_49851205 12.80 ENST00000601675.5
PTOV1
PTOV1 extended AT-hook containing adaptor protein
chr19_+_49851136 12.44 ENST00000391842.5
PTOV1
PTOV1 extended AT-hook containing adaptor protein
chr7_+_157336961 12.09 ENST00000429029.6
DNAJB6
DnaJ heat shock protein family (Hsp40) member B6
chr8_+_37736612 11.99 ENST00000518526.5
ENST00000523887.5
ENST00000648919.1
ENST00000519638.3
ERLIN2
ER lipid raft associated 2
chr19_+_49851173 11.83 ENST00000599732.5
PTOV1
PTOV1 extended AT-hook containing adaptor protein
chrX_-_107000185 11.62 ENST00000355610.9
MORC4
MORC family CW-type zinc finger 4
chr19_+_2269520 11.43 ENST00000602676.6
ENST00000582888.8
OAZ1
ornithine decarboxylase antizyme 1
chr12_-_48682158 11.40 ENST00000553086.5
ENST00000548304.1
ENST00000550347.5
ENST00000420613.7
ENST00000550931.5
ENST00000550870.1
KANSL2
KAT8 regulatory NSL complex subunit 2
chr1_-_25905989 11.27 ENST00000399728.5
STMN1
stathmin 1
chr2_+_200305976 10.79 ENST00000358677.9
SPATS2L
spermatogenesis associated serine rich 2 like
chr1_+_174999925 10.64 ENST00000367679.7
CACYBP
calcyclin binding protein
chr20_-_44960348 10.55 ENST00000372813.4
TOMM34
translocase of outer mitochondrial membrane 34
chr6_-_106325416 10.34 ENST00000343245.7
ATG5
autophagy related 5
chr6_+_4889992 10.32 ENST00000343762.5
CDYL
chromodomain Y like
chrX_+_123960519 10.31 ENST00000455404.5
ENST00000218089.13
STAG2
stromal antigen 2
chr3_+_130894050 10.17 ENST00000510168.6
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr12_-_124917340 10.11 ENST00000542416.1
UBC
ubiquitin C
chr5_-_140673568 9.99 ENST00000542735.2
DND1
DND microRNA-mediated repression inhibitor 1
chr14_+_71586261 9.63 ENST00000358550.6
SIPA1L1
signal induced proliferation associated 1 like 1
chr2_+_85539158 9.59 ENST00000306434.8
MAT2A
methionine adenosyltransferase 2A
chr2_+_227813834 9.49 ENST00000358813.5
ENST00000409189.7
CCL20
C-C motif chemokine ligand 20
chr12_-_122526929 9.48 ENST00000331738.12
ENST00000528279.1
ENST00000344591.8
ENST00000526560.6
RSRC2
arginine and serine rich coiled-coil 2
chr22_+_29268248 8.67 ENST00000436425.5
ENST00000447973.5
ENST00000397938.7
ENST00000406548.5
ENST00000437155.6
ENST00000415761.5
ENST00000331029.11
EWSR1
EWS RNA binding protein 1
chr1_-_120176450 8.38 ENST00000578049.4
SEC22B
SEC22 homolog B, vesicle trafficking protein
chr11_-_27700472 8.32 ENST00000418212.5
ENST00000533246.5
BDNF
brain derived neurotrophic factor
chr5_+_134371561 8.02 ENST00000265339.7
ENST00000506787.5
ENST00000507277.1
UBE2B
ubiquitin conjugating enzyme E2 B
chr3_+_130894157 7.90 ENST00000504948.5
ENST00000513801.5
ENST00000505072.5
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr18_+_59899988 7.79 ENST00000316660.7
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr3_+_130894382 7.53 ENST00000509662.5
ENST00000328560.12
ENST00000428331.6
ENST00000359644.7
ENST00000422190.6
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr7_+_157336988 7.46 ENST00000262177.9
ENST00000417758.5
ENST00000443280.5
DNAJB6
DnaJ heat shock protein family (Hsp40) member B6
chr15_+_78872809 7.44 ENST00000331268.9
MORF4L1
mortality factor 4 like 1
chr4_-_25863537 7.36 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L3
SEL1L family member 3
chr15_+_78872881 7.24 ENST00000559930.5
ENST00000426013.7
MORF4L1
mortality factor 4 like 1
chr16_-_18375069 7.22 ENST00000545114.5
NPIPA9
nuclear pore complex interacting protein family, member A9
chr6_-_41941795 7.10 ENST00000372991.9
CCND3
cyclin D3
chr11_+_20363780 6.78 ENST00000532505.1
HTATIP2
HIV-1 Tat interactive protein 2
chr19_-_46714269 6.60 ENST00000600194.5
PRKD2
protein kinase D2
chr3_+_130893959 6.42 ENST00000508532.5
ENST00000533801.6
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr5_+_74766981 6.33 ENST00000296802.9
NSA2
NSA2 ribosome biogenesis factor
chr6_-_41941507 6.32 ENST00000372987.8
CCND3
cyclin D3
chr5_+_141223332 6.31 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
PCDHB14
ENSG00000279983.1
protocadherin beta 14
novel protein
chr10_-_20897288 6.12 ENST00000377122.9
NEBL
nebulette
chr5_-_178187364 6.01 ENST00000463439.3
GMCL2
germ cell-less 2, spermatogenesis associated
chr6_-_41941728 6.00 ENST00000414200.6
CCND3
cyclin D3
chr21_+_33403466 5.76 ENST00000405436.5
IFNGR2
interferon gamma receptor 2
chr2_+_200306648 5.40 ENST00000409140.8
SPATS2L
spermatogenesis associated serine rich 2 like
chr5_+_446139 5.34 ENST00000315013.9
EXOC3
exocyst complex component 3
chr18_-_21704763 5.24 ENST00000580981.5
ENST00000289119.7
ABHD3
abhydrolase domain containing 3, phospholipase
chr17_-_64230727 5.19 ENST00000583097.5
ENST00000615733.4
TEX2
testis expressed 2
chr2_-_47906437 4.85 ENST00000403359.8
FBXO11
F-box protein 11
chr2_-_237590660 4.02 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr12_+_65169546 3.67 ENST00000308330.3
LEMD3
LEM domain containing 3
chr11_-_47848467 3.57 ENST00000378460.6
NUP160
nucleoporin 160
chr18_+_11751467 2.63 ENST00000535121.5
GNAL
G protein subunit alpha L
chr3_+_186783567 2.47 ENST00000323963.10
ENST00000440191.6
EIF4A2
eukaryotic translation initiation factor 4A2
chr19_-_46471484 2.33 ENST00000313683.15
ENST00000602246.1
PNMA8A
PNMA family member 8A
chr6_+_31715339 2.21 ENST00000375824.1
ENST00000375825.7
LY6G6D
lymphocyte antigen 6 family member G6D
chr12_+_69738853 1.92 ENST00000247833.12
ENST00000378815.10
ENST00000483530.6
RAB3IP
RAB3A interacting protein
chr22_+_32475257 1.85 ENST00000397426.5
FBXO7
F-box protein 7
chr3_-_195876635 1.77 ENST00000672669.1
ENST00000672886.1
ENST00000672098.1
ENST00000671767.1
ENST00000672548.1
TNK2
tyrosine kinase non receptor 2
chr7_+_130380339 1.64 ENST00000481342.5
ENST00000604896.5
ENST00000011292.8
CPA1
carboxypeptidase A1
chr7_+_130381092 1.41 ENST00000484324.1
CPA1
carboxypeptidase A1
chr17_+_42017020 1.39 ENST00000307641.9
NKIRAS2
NFKB inhibitor interacting Ras like 2
chr11_+_20364119 1.18 ENST00000532081.1
ENST00000531058.1
HTATIP2
HIV-1 Tat interactive protein 2
chr17_+_34319427 0.51 ENST00000394620.2
CCL8
C-C motif chemokine ligand 8
chr18_+_11751494 0.44 ENST00000269162.9
GNAL
G protein subunit alpha L
chr12_-_57111338 0.31 ENST00000538913.6
ENST00000537215.6
ENST00000300134.8
ENST00000454075.7
ENST00000640254.2
ENST00000553275.1
ENST00000553533.2
STAT6
signal transducer and activator of transcription 6
chr19_-_18538371 0.20 ENST00000596015.1
FKBP8
FKBP prolyl isomerase 8
chr12_-_56636318 0.09 ENST00000549506.5
ENST00000379441.7
ENST00000551812.5
BAZ2A
bromodomain adjacent to zinc finger domain 2A
chr1_-_24143112 0.08 ENST00000270800.2
IL22RA1
interleukin 22 receptor subunit alpha 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
27.6 386.5 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
25.4 76.1 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
23.1 207.6 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
21.9 109.5 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
21.0 63.0 GO:0002368 B cell cytokine production(GO:0002368)
16.6 66.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
15.0 59.9 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
14.7 58.7 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
14.5 58.0 GO:0043335 protein unfolding(GO:0043335)
13.3 106.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
10.3 30.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
9.7 38.9 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
8.2 138.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
6.9 96.1 GO:0015074 DNA integration(GO:0015074)
6.5 65.2 GO:0000012 single strand break repair(GO:0000012)
5.3 32.0 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
5.3 21.0 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
5.1 15.2 GO:2001168 histone H3-K79 methylation(GO:0034729) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
4.9 19.4 GO:0009956 radial pattern formation(GO:0009956)
4.7 32.7 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
4.7 32.6 GO:0010044 response to aluminum ion(GO:0010044)
4.3 68.8 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
4.1 110.7 GO:0043968 histone H2A acetylation(GO:0043968)
4.0 20.1 GO:0007412 axon target recognition(GO:0007412)
3.7 33.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
3.4 10.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
3.4 13.7 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
3.2 9.5 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
3.1 86.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
3.1 40.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
3.1 31.0 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
2.8 64.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
2.8 8.3 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
2.7 32.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
2.7 8.0 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
2.6 23.6 GO:0071492 cellular response to UV-A(GO:0071492)
2.5 35.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.4 19.6 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
2.4 9.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
2.4 23.6 GO:0006983 ER overload response(GO:0006983)
2.3 11.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
2.2 97.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
2.1 36.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
2.0 12.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.9 17.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.4 18.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.3 4.0 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.1 16.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.0 8.4 GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.9 7.8 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.8 29.3 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.7 34.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.7 3.7 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.7 6.6 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.6 11.4 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.5 5.3 GO:0051601 exocyst localization(GO:0051601)
0.5 10.0 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.5 10.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.3 4.9 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.3 22.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3 34.3 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.3 6.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.3 58.5 GO:0006997 nucleus organization(GO:0006997)
0.3 56.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 6.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 20.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 24.3 GO:0007062 sister chromatid cohesion(GO:0007062)
0.2 6.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 5.8 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 9.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 15.6 GO:0007030 Golgi organization(GO:0007030)
0.1 1.8 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.1 3.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 2.2 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 2.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 10.3 GO:0016573 histone acetylation(GO:0016573)
0.1 10.0 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 13.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 13.8 GO:0051170 nuclear import(GO:0051170)
0.0 1.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
25.4 76.1 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
20.3 386.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
13.7 109.5 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
10.1 273.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
10.0 59.9 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
7.0 63.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696)
6.1 60.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
5.7 17.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
3.8 56.9 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
3.5 110.7 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
3.3 33.3 GO:0061574 ASAP complex(GO:0061574)
3.2 9.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
2.2 35.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
2.1 52.7 GO:0044295 axonal growth cone(GO:0044295)
2.1 114.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
2.1 10.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
1.7 34.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
1.6 8.0 GO:0033503 HULC complex(GO:0033503)
1.4 86.5 GO:1904115 axon cytoplasm(GO:1904115)
1.4 15.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.1 13.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.0 22.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.8 135.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.6 71.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.5 90.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 10.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.4 19.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 5.3 GO:0000145 exocyst(GO:0000145)
0.3 76.2 GO:0000793 condensed chromosome(GO:0000793)
0.3 22.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.3 25.7 GO:0000775 chromosome, centromeric region(GO:0000775)
0.3 23.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 1.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 6.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 20.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 65.1 GO:0000790 nuclear chromatin(GO:0000790)
0.2 47.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 11.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 16.1 GO:0034399 nuclear periphery(GO:0034399)
0.1 2.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 32.0 GO:0005802 trans-Golgi network(GO:0005802)
0.1 93.3 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 86.0 GO:0005730 nucleolus(GO:0005730)
0.1 6.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.3 GO:0000785 chromatin(GO:0000785)
0.0 14.6 GO:0005635 nuclear envelope(GO:0005635)
0.0 11.9 GO:0005874 microtubule(GO:0005874)
0.0 2.2 GO:0030175 filopodium(GO:0030175)
0.0 6.3 GO:0016607 nuclear speck(GO:0016607)
0.0 4.4 GO:0045121 membrane raft(GO:0045121)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
44.1 176.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
25.4 76.1 GO:0002135 CTP binding(GO:0002135)
22.1 66.4 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
21.7 65.2 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
15.5 170.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
13.2 52.7 GO:0032767 copper-dependent protein binding(GO:0032767)
13.0 78.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
12.7 25.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
11.3 146.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
10.9 86.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
10.5 63.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
10.1 40.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
8.5 34.0 GO:0070404 NADH binding(GO:0070404)
7.0 210.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
6.5 58.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
6.4 58.0 GO:0030911 TPR domain binding(GO:0030911)
4.9 68.8 GO:0046790 virion binding(GO:0046790)
3.8 132.9 GO:0001671 ATPase activator activity(GO:0001671)
3.4 17.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
3.3 20.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
3.2 159.2 GO:0030544 Hsp70 protein binding(GO:0030544)
3.2 9.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
3.0 21.0 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
2.7 13.7 GO:1903135 cupric ion binding(GO:1903135)
2.7 32.7 GO:0097157 pre-mRNA intronic binding(GO:0097157) N6-methyladenosine-containing RNA binding(GO:1990247)
2.3 11.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
2.1 8.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
2.1 10.3 GO:0019776 Atg8 ligase activity(GO:0019776)
1.9 59.9 GO:0042288 MHC class I protein binding(GO:0042288)
1.7 5.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
1.4 5.8 GO:0004906 interferon-gamma receptor activity(GO:0004906)
1.4 11.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
1.1 32.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.0 29.0 GO:0070034 telomerase RNA binding(GO:0070034)
1.0 106.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.9 29.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.8 30.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.7 132.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.7 10.0 GO:0017091 AU-rich element binding(GO:0017091)
0.6 18.8 GO:0070717 poly-purine tract binding(GO:0070717)
0.6 19.4 GO:0001972 retinoic acid binding(GO:0001972)
0.5 56.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.5 15.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 20.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 16.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 19.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.3 4.9 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.3 2.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.3 6.1 GO:0031005 filamin binding(GO:0031005)
0.3 38.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 6.6 GO:0004697 protein kinase C activity(GO:0004697)
0.2 9.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 12.0 GO:0015485 cholesterol binding(GO:0015485)
0.2 8.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 10.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 23.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 13.7 GO:0000149 SNARE binding(GO:0000149)
0.1 3.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 20.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 3.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 3.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 4.0 GO:0019003 GDP binding(GO:0019003)
0.1 24.3 GO:0045296 cadherin binding(GO:0045296)
0.0 2.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.5 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 61.0 GO:0003723 RNA binding(GO:0003723)
0.0 9.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 84.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
2.2 65.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
2.1 58.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
1.6 66.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.3 86.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
1.1 72.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.0 68.8 PID IL6 7 PATHWAY IL6-mediated signaling events
1.0 142.7 PID CMYB PATHWAY C-MYB transcription factor network
0.9 57.2 PID PLK1 PATHWAY PLK1 signaling events
0.9 60.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.8 76.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.8 11.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.6 52.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.5 18.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.5 34.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 27.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.4 98.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 19.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.4 11.4 PID AURORA A PATHWAY Aurora A signaling
0.3 13.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 15.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 3.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 5.3 PID INSULIN PATHWAY Insulin Pathway
0.1 7.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.1 PID BARD1 PATHWAY BARD1 signaling events
0.1 4.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.8 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
12.1 386.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
8.7 96.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
4.9 68.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
4.2 76.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
2.8 58.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
2.7 109.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.6 106.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
1.5 97.5 REACTOME G1 PHASE Genes involved in G1 Phase
1.4 40.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.4 21.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.1 11.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
1.1 63.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.8 66.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.8 129.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.8 32.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.7 65.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.6 32.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.6 100.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.3 9.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 13.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 5.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 5.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 24.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 3.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 10.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 19.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 21.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 20.5 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 2.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA