ISMARA results: IKZF2

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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for IKZF2

Z-value: 0.68

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Transcription factors associated with IKZF2

Gene Symbol	Gene ID	Gene Info
IKZF2 Ensembl NCBI GeneCards UniProt	ENSG00000030419.17	IKZF2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
IKZF2	hg38_v1_chr2_-_213151590_213151619	0.08	2.2e-01	Click!

Activity profile of IKZF2 motif

Sorted Z-values of IKZF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr12_-_91179517 Show fit	13.32	ENST00000551354.1	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr2_+_188974364 Show fit	11.94	ENST00000304636.9 ENST00000317840.9	COL3A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type III alpha 1 chain
chr12_-_91179472 Show fit	11.24	ENST00000550099.5 ENST00000546391.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr7_+_94394886 Show fit	11.03	ENST00000297268.11 ENST00000620463.1	COL1A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type I alpha 2 chain
chr12_-_91179355 Show fit	10.22	ENST00000550563.5 ENST00000546370.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr1_-_56579555 Show fit	7.00	ENST00000371250.4	PLPP3 Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase 3
chr5_-_42811884 Show fit	6.56	ENST00000514985.6 ENST00000511224.5 ENST00000507920.5 ENST00000510965.1	SELENOP Ensembl NCBI GeneCards UniProt Show fit	selenoprotein P
chr5_-_151686908 Show fit	5.36	ENST00000231061.9	SPARC Ensembl NCBI GeneCards UniProt Show fit	secreted protein acidic and cysteine rich
chr18_-_55403682 Show fit	4.67	ENST00000564228.5 ENST00000630828.2	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr2_+_189857393 Show fit	4.30	ENST00000452382.1	PMS1 Ensembl NCBI GeneCards UniProt Show fit	PMS1 homolog 1, mismatch repair system component
chr8_+_79611727 Show fit	4.04	ENST00000518491.1	STMN2 Ensembl NCBI GeneCards UniProt Show fit	stathmin 2
chr4_+_157220654 Show fit	3.88	ENST00000393815.6	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr9_-_90642855 Show fit	3.82	ENST00000637905.1	DIRAS2 Ensembl NCBI GeneCards UniProt Show fit	DIRAS family GTPase 2
chr1_-_203182805 Show fit	3.69	ENST00000404436.2	CHI3L1 Ensembl NCBI GeneCards UniProt Show fit	chitinase 3 like 1
chr4_+_157220691 Show fit	3.64	ENST00000509417.5 ENST00000645636.1 ENST00000296526.12 ENST00000264426.14	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr2_+_17753852 Show fit	3.56	ENST00000317402.11	GEN1 Ensembl NCBI GeneCards UniProt Show fit	GEN1 Holliday junction 5' flap endonuclease
chr2_+_17754116 Show fit	3.33	ENST00000381254.7 ENST00000524465.5 ENST00000532257.1	GEN1 Ensembl NCBI GeneCards UniProt Show fit	GEN1 Holliday junction 5' flap endonuclease
chr8_+_79611036 Show fit	3.28	ENST00000220876.12 ENST00000518111.5	STMN2 Ensembl NCBI GeneCards UniProt Show fit	stathmin 2
chr10_-_78029487 Show fit	3.25	ENST00000372371.8	POLR3A Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase III subunit A
chr11_+_126283059 Show fit	3.25	ENST00000392679.6 ENST00000392678.7 ENST00000392680.6	TIRAP Ensembl NCBI GeneCards UniProt Show fit	TIR domain containing adaptor protein
chrX_+_103776831 Show fit	3.24	ENST00000621218.5 ENST00000619236.1	PLP1 Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 1
chrX_+_103776493 Show fit	3.22	ENST00000433491.5 ENST00000612423.4 ENST00000443502.5	PLP1 Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 1
chr1_+_100719734 Show fit	3.16	ENST00000370119.8 ENST00000294728.7 ENST00000347652.6 ENST00000370115.1	VCAM1 Ensembl NCBI GeneCards UniProt Show fit	vascular cell adhesion molecule 1
chr13_-_37598750 Show fit	3.12	ENST00000379743.8 ENST00000379742.4 ENST00000379749.8 ENST00000379747.9 ENST00000541179.5 ENST00000541481.5	POSTN Ensembl NCBI GeneCards UniProt Show fit	periostin
chr5_-_16508858 Show fit	3.01	ENST00000684456.1	RETREG1 Ensembl NCBI GeneCards UniProt Show fit	reticulophagy regulator 1
chr2_-_135531172 Show fit	2.98	ENST00000264159.11	ZRANB3 Ensembl NCBI GeneCards UniProt Show fit	zinc finger RANBP2-type containing 3
chr11_-_56292254 Show fit	2.93	ENST00000641600.1	OR8H1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 8 subfamily H member 1
chr6_+_31670167 Show fit	2.91	ENST00000375864.4	LY6G5B Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 6 family member G5B
chr4_+_168832005 Show fit	2.91	ENST00000393726.7 ENST00000507735.6	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr4_+_26320782 Show fit	2.90	ENST00000514807.5 ENST00000348160.9	RBPJ Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr4_+_123399488 Show fit	2.90	ENST00000394339.2	SPRY1 Ensembl NCBI GeneCards UniProt Show fit	sprouty RTK signaling antagonist 1
chr5_-_16508951 Show fit	2.89	ENST00000682628.1	RETREG1 Ensembl NCBI GeneCards UniProt Show fit	reticulophagy regulator 1
chr14_-_35121950 Show fit	2.88	ENST00000554361.5 ENST00000261475.10	PPP2R3C Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit B''gamma
chr1_+_152878312 Show fit	2.84	ENST00000368765.4	SMCP Ensembl NCBI GeneCards UniProt Show fit	sperm mitochondria associated cysteine rich protein
chrX_+_136148440 Show fit	2.80	ENST00000627383.2 ENST00000630084.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr3_+_10026409 Show fit	2.78	ENST00000287647.7 ENST00000676013.1 ENST00000675286.1 ENST00000419585.5	FANCD2 Ensembl NCBI GeneCards UniProt Show fit	FA complementation group D2
chr5_-_16508812 Show fit	2.73	ENST00000683414.1	RETREG1 Ensembl NCBI GeneCards UniProt Show fit	reticulophagy regulator 1
chr4_+_26320563 Show fit	2.71	ENST00000361572.10	RBPJ Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chrX_+_55452119 Show fit	2.65	ENST00000342972.3	MAGEH1 Ensembl NCBI GeneCards UniProt Show fit	MAGE family member H1
chr6_+_142147162 Show fit	2.65	ENST00000452973.6 ENST00000620996.4 ENST00000367621.1 ENST00000367630.9	VTA1 Ensembl NCBI GeneCards UniProt Show fit	vesicle trafficking 1
chr5_-_16508990 Show fit	2.52	ENST00000399793.6	RETREG1 Ensembl NCBI GeneCards UniProt Show fit	reticulophagy regulator 1
chr2_-_135530561 Show fit	2.51	ENST00000536680.5 ENST00000401392.5	ZRANB3 Ensembl NCBI GeneCards UniProt Show fit	zinc finger RANBP2-type containing 3
chr2_-_175005357 Show fit	2.46	ENST00000409156.7 ENST00000444573.2 ENST00000409900.9	CHN1 Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr5_-_16508788 Show fit	2.45	ENST00000682142.1	RETREG1 Ensembl NCBI GeneCards UniProt Show fit	reticulophagy regulator 1
chr2_-_189179754 Show fit	2.37	ENST00000374866.9 ENST00000618828.1	COL5A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type V alpha 2 chain
chr13_+_57631735 Show fit	2.33	ENST00000377918.8	PCDH17 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 17
chr15_-_88256139 Show fit	2.31	ENST00000626019.2	NTRK3 Ensembl NCBI GeneCards UniProt Show fit	neurotrophic receptor tyrosine kinase 3
chr3_-_16605416 Show fit	2.23	ENST00000399444.7	DAZL Ensembl NCBI GeneCards UniProt Show fit	deleted in azoospermia like
chr14_-_44961889 Show fit	2.22	ENST00000579157.1 ENST00000396128.9 ENST00000556500.1	KLHL28 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 28
chr3_-_18424533 Show fit	2.21	ENST00000417717.6	SATB1 Ensembl NCBI GeneCards UniProt Show fit	SATB homeobox 1
chr18_-_24272179 Show fit	2.20	ENST00000399443.7	OSBPL1A Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein like 1A
chr3_-_18438767 Show fit	2.15	ENST00000454909.6	SATB1 Ensembl NCBI GeneCards UniProt Show fit	SATB homeobox 1
chr1_+_168179030 Show fit	2.14	ENST00000367830.3	TIPRL Ensembl NCBI GeneCards UniProt Show fit	TOR signaling pathway regulator
chr3_+_196744 Show fit	2.08	ENST00000256509.7 ENST00000397491.6	CHL1 Ensembl NCBI GeneCards UniProt Show fit	cell adhesion molecule L1 like
chr6_-_131063233 Show fit	2.07	ENST00000392427.7 ENST00000337057.8 ENST00000525271.5 ENST00000527411.5	EPB41L2 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr2_-_101151253 Show fit	2.07	ENST00000376840.8 ENST00000409318.2	TBC1D8 Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 8
chr4_-_152382522 Show fit	2.05	ENST00000296555.11	FBXW7 Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 7
chr9_+_121299793 Show fit	2.05	ENST00000373818.8	GSN Ensembl NCBI GeneCards UniProt Show fit	gelsolin
chr15_-_23447234 Show fit	2.03	ENST00000312015.6 ENST00000345070.5 ENST00000567107.6	GOLGA6L2 Ensembl NCBI GeneCards UniProt Show fit	golgin A6 family like 2
chr6_-_128520358 Show fit	2.03	ENST00000368215.7 ENST00000532331.5 ENST00000368213.9 ENST00000368207.7 ENST00000525459.1 ENST00000368226.9 ENST00000368210.7	PTPRK Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type K
chr20_+_45881218 Show fit	2.01	ENST00000372523.1	ZSWIM1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger SWIM-type containing 1
chr7_+_138797952 Show fit	2.01	ENST00000397602.7 ENST00000442682.7 ENST00000458494.1 ENST00000413208.1	TMEM213 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 213
chr4_-_86357722 Show fit	1.99	ENST00000641341.1 ENST00000642038.1 ENST00000641116.1 ENST00000641767.1 ENST00000639242.1 ENST00000638313.1	MAPK10 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 10
chr2_+_17539964 Show fit	1.98	ENST00000457525.5	VSNL1 Ensembl NCBI GeneCards UniProt Show fit	visinin like 1
chrX_+_136169833 Show fit	1.92	ENST00000628032.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr15_-_89815332 Show fit	1.91	ENST00000559874.2	ANPEP Ensembl NCBI GeneCards UniProt Show fit	alanyl aminopeptidase, membrane
chr10_+_119818699 Show fit	1.91	ENST00000650409.1	INPP5F Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-5-phosphatase F
chr6_-_131063272 Show fit	1.90	ENST00000445890.6 ENST00000368128.6 ENST00000628542.2	EPB41L2 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr2_+_48568981 Show fit	1.87	ENST00000394754.5	STON1-GTF2A1L Ensembl NCBI GeneCards UniProt Show fit	STON1-GTF2A1L readthrough
chr10_-_110919146 Show fit	1.86	ENST00000652396.1 ENST00000423273.5 ENST00000436562.1 ENST00000651952.1 ENST00000448814.7 ENST00000652400.1 ENST00000447005.5 ENST00000454061.5	BBIP1 Ensembl NCBI GeneCards UniProt Show fit	BBSome interacting protein 1
chr18_-_55422492 Show fit	1.83	ENST00000561992.5 ENST00000630712.2	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chrX_+_136169624 Show fit	1.80	ENST00000394153.6	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr2_+_27078598 Show fit	1.80	ENST00000380320.9	EMILIN1 Ensembl NCBI GeneCards UniProt Show fit	elastin microfibril interfacer 1
chr9_+_2159672 Show fit	1.80	ENST00000634343.1	SMARCA2 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_110918934 Show fit	1.77	ENST00000605742.5	BBIP1 Ensembl NCBI GeneCards UniProt Show fit	BBSome interacting protein 1
chr14_+_28766755 Show fit	1.74	ENST00000313071.7	FOXG1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box G1
chr5_-_134371004 Show fit	1.72	ENST00000521755.1 ENST00000523054.5 ENST00000518409.1	CDKL3 Ensembl NCBI GeneCards UniProt Show fit ENSG00000273345.5 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase like 3 novel transcript
chr6_+_147508645 Show fit	1.72	ENST00000367474.2	SAMD5 Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 5
chr4_+_176065827 Show fit	1.67	ENST00000508596.6	WDR17 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 17
chr10_+_110919595 Show fit	1.66	ENST00000369452.9	SHOC2 Ensembl NCBI GeneCards UniProt Show fit	SHOC2 leucine rich repeat scaffold protein
chr1_+_50105666 Show fit	1.66	ENST00000651347.1	ELAVL4 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 4
chr6_-_131063207 Show fit	1.61	ENST00000530481.5	EPB41L2 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr1_+_103745323 Show fit	1.59	ENST00000684141.1	AMY1C Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 1C
chr15_-_88256158 Show fit	1.58	ENST00000317501.7 ENST00000629765.2 ENST00000557856.5 ENST00000558676.5	NTRK3 Ensembl NCBI GeneCards UniProt Show fit	neurotrophic receptor tyrosine kinase 3
chr8_-_132625378 Show fit	1.56	ENST00000522789.5	LRRC6 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 6
chr15_-_88256717 Show fit	1.56	ENST00000355254.6 ENST00000360948.6 ENST00000357724.6 ENST00000540489.6 ENST00000394480.6	NTRK3 Ensembl NCBI GeneCards UniProt Show fit	neurotrophic receptor tyrosine kinase 3
chr1_+_159009886 Show fit	1.54	ENST00000340979.10 ENST00000368131.8 ENST00000295809.12 ENST00000368132.7	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr14_+_44962177 Show fit	1.52	ENST00000361462.7 ENST00000361577.7	TOGARAM1 Ensembl NCBI GeneCards UniProt Show fit	TOG array regulator of axonemal microtubules 1
chr18_-_55321640 Show fit	1.51	ENST00000637169.2	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr2_-_159798043 Show fit	1.49	ENST00000664982.1 ENST00000259053.6	ENSG00000287091.1 Ensembl NCBI GeneCards UniProt Show fit CD302 Ensembl NCBI GeneCards UniProt Show fit	novel transcript, sense intronic to CD302and LY75-CD302 CD302 molecule
chr11_-_72674394 Show fit	1.46	ENST00000418754.6 ENST00000334456.10 ENST00000542969.2	PDE2A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr19_+_48270079 Show fit	1.46	ENST00000595607.6	ZNF114 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 114
chr10_-_37858037 Show fit	1.45	ENST00000395873.7 ENST00000357328.8 ENST00000395874.2	ZNF248 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 248
chr7_-_135510074 Show fit	1.45	ENST00000428680.6 ENST00000423368.6 ENST00000451834.5 ENST00000361528.8 ENST00000541284.5 ENST00000315544.6	CNOT4 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 4
chrX_+_136169664 Show fit	1.42	ENST00000456445.5	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr1_+_103655760 Show fit	1.41	ENST00000370083.9	AMY1A Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 1A
chr8_-_18684033 Show fit	1.40	ENST00000614430.3	PSD3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing 3
chr1_+_159010002 Show fit	1.38	ENST00000359709.7	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr4_-_89057156 Show fit	1.38	ENST00000511976.5 ENST00000509094.5 ENST00000264344.10 ENST00000515600.1	FAM13A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 13 member A
chr7_+_74027770 Show fit	1.37	ENST00000445912.5 ENST00000621115.4	ELN Ensembl NCBI GeneCards UniProt Show fit	elastin
chr2_-_118847638 Show fit	1.35	ENST00000295206.7	EN1 Ensembl NCBI GeneCards UniProt Show fit	engrailed homeobox 1
chr1_+_40161355 Show fit	1.35	ENST00000372771.5	RLF Ensembl NCBI GeneCards UniProt Show fit	RLF zinc finger
chr6_+_122789049 Show fit	1.34	ENST00000539041.5	SMPDL3A Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase acid like 3A
chr3_+_12351493 Show fit	1.34	ENST00000683699.1	PPARG Ensembl NCBI GeneCards UniProt Show fit	peroxisome proliferator activated receptor gamma
chrX_+_136169891 Show fit	1.33	ENST00000449474.5	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr5_-_109409938 Show fit	1.32	ENST00000361189.7	PJA2 Ensembl NCBI GeneCards UniProt Show fit	praja ring finger ubiquitin ligase 2
chr1_+_103571077 Show fit	1.32	ENST00000610648.1	AMY2B Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 2B
chrX_+_81202066 Show fit	1.30	ENST00000373212.6	SH3BGRL Ensembl NCBI GeneCards UniProt Show fit	SH3 domain binding glutamate rich protein like
chr2_-_127675065 Show fit	1.29	ENST00000545738.6 ENST00000409808.6	LIMS2 Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 2
chr3_-_138174879 Show fit	1.29	ENST00000260803.9	DBR1 Ensembl NCBI GeneCards UniProt Show fit	debranching RNA lariats 1
chr4_-_152352800 Show fit	1.29	ENST00000393956.9	FBXW7 Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 7
chr3_-_183555696 Show fit	1.29	ENST00000341319.8	KLHL6 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 6
chr17_+_7884783 Show fit	1.28	ENST00000380358.9	CHD3 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 3
chr12_-_55688891 Show fit	1.28	ENST00000557555.2	ITGA7 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 7
chr5_+_32710630 Show fit	1.26	ENST00000326958.5	NPR3 Ensembl NCBI GeneCards UniProt Show fit	natriuretic peptide receptor 3
chr1_-_48400826 Show fit	1.23	ENST00000371841.1	SPATA6 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 6
chr5_-_147831663 Show fit	1.22	ENST00000296695.10	SPINK1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor Kazal type 1
chr6_+_43182165 Show fit	1.19	ENST00000372647.6 ENST00000252050.9	CUL9 Ensembl NCBI GeneCards UniProt Show fit	cullin 9
chr6_+_122789197 Show fit	1.18	ENST00000368440.5	SMPDL3A Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase acid like 3A
chrX_-_15601077 Show fit	1.18	ENST00000680121.1	ACE2 Ensembl NCBI GeneCards UniProt Show fit	angiotensin I converting enzyme 2
chr7_+_93921720 Show fit	1.16	ENST00000248564.6	GNG11 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit gamma 11
chr7_+_74028066 Show fit	1.16	ENST00000431562.5 ENST00000320492.11 ENST00000438906.5	ELN Ensembl NCBI GeneCards UniProt Show fit	elastin
chrX_-_133985449 Show fit	1.15	ENST00000631057.2	GPC3 Ensembl NCBI GeneCards UniProt Show fit	glypican 3
chr12_-_104050112 Show fit	1.15	ENST00000547583.1 ENST00000546851.1 ENST00000360814.9	GLT8D2 Ensembl NCBI GeneCards UniProt Show fit	glycosyltransferase 8 domain containing 2
chr9_+_2159850 Show fit	1.15	ENST00000416751.2	SMARCA2 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_26195313 Show fit	1.14	ENST00000422622.3	SSPN Ensembl NCBI GeneCards UniProt Show fit	sarcospan
chr4_-_73620391 Show fit	1.14	ENST00000395777.6 ENST00000307439.10	RASSF6 Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 6
chr8_+_96584920 Show fit	1.13	ENST00000521590.5	SDC2 Ensembl NCBI GeneCards UniProt Show fit	syndecan 2
chr6_+_31615215 Show fit	1.13	ENST00000337917.11 ENST00000376059.8	AIF1 Ensembl NCBI GeneCards UniProt Show fit	allograft inflammatory factor 1
chr3_-_183099508 Show fit	1.13	ENST00000476176.5	MCCC1 Ensembl NCBI GeneCards UniProt Show fit	methylcrotonoyl-CoA carboxylase 1
chr18_-_55422306 Show fit	1.12	ENST00000566777.5 ENST00000626584.2	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr10_+_117543567 Show fit	1.12	ENST00000616794.1	EMX2 Ensembl NCBI GeneCards UniProt Show fit	empty spiracles homeobox 2
chr17_+_79022908 Show fit	1.11	ENST00000354124.7 ENST00000580454.5	C1QTNF1 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 1
chr12_-_8540873 Show fit	1.11	ENST00000545274.5 ENST00000446457.6 ENST00000299663.8	CLEC4E Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 4 member E
chr21_-_26967057 Show fit	1.08	ENST00000284987.6	ADAMTS5 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 5
chr20_-_52191697 Show fit	1.08	ENST00000361387.6	ZFP64 Ensembl NCBI GeneCards UniProt Show fit	ZFP64 zinc finger protein
chr8_+_39913881 Show fit	1.07	ENST00000518237.6	IDO1 Ensembl NCBI GeneCards UniProt Show fit	indoleamine 2,3-dioxygenase 1
chrX_+_21855987 Show fit	1.07	ENST00000429584.3	YY2 Ensembl NCBI GeneCards UniProt Show fit	YY2 transcription factor
chr2_+_209580024 Show fit	1.06	ENST00000392194.5	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr10_+_103277129 Show fit	1.04	ENST00000369849.9	INA Ensembl NCBI GeneCards UniProt Show fit	internexin neuronal intermediate filament protein alpha
chr7_+_74028127 Show fit	1.04	ENST00000438880.5 ENST00000414324.5 ENST00000380562.8 ENST00000380575.8 ENST00000380584.8 ENST00000458204.5 ENST00000357036.9 ENST00000417091.5 ENST00000429192.5 ENST00000252034.12 ENST00000442310.5 ENST00000380553.8 ENST00000380576.9 ENST00000428787.5 ENST00000320399.10	ELN Ensembl NCBI GeneCards UniProt Show fit	elastin
chr15_-_58014097 Show fit	1.04	ENST00000559517.5	ALDH1A2 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family member A2
chr12_+_62466791 Show fit	1.01	ENST00000641654.1 ENST00000546600.5 ENST00000393630.8 ENST00000552738.5 ENST00000393629.6 ENST00000552115.5	MON2 Ensembl NCBI GeneCards UniProt Show fit	MON2 homolog, regulator of endosome-to-Golgi trafficking
chrX_+_101550537 Show fit	1.01	ENST00000372829.8	ARMCX1 Ensembl NCBI GeneCards UniProt Show fit	armadillo repeat containing X-linked 1
chr3_-_49120887 Show fit	1.01	ENST00000453664.5 ENST00000398888.6	USP19 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 19
chr8_+_39584577 Show fit	1.01	ENST00000379866.5 ENST00000520772.5	ADAM18 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 18
chr8_-_18684093 Show fit	1.00	ENST00000428502.6	PSD3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing 3
chr6_+_29587455 Show fit	1.00	ENST00000383640.4	OR2H2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily H member 2
chr8_+_39584562 Show fit	0.99	ENST00000265707.10	ADAM18 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 18
chr14_-_64503775 Show fit	0.99	ENST00000608382.6	ZBTB25 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 25
chr6_+_68635273 Show fit	0.98	ENST00000370598.6	ADGRB3 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor B3
chr19_+_43716070 Show fit	0.97	ENST00000244314.6	IRGC Ensembl NCBI GeneCards UniProt Show fit	immunity related GTPase cinema
chr2_-_127675459 Show fit	0.96	ENST00000355119.9	LIMS2 Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 2
chr1_-_169630115 Show fit	0.92	ENST00000263686.11 ENST00000367788.6	SELP Ensembl NCBI GeneCards UniProt Show fit	selectin P
chr4_-_73620629 Show fit	0.92	ENST00000342081.7	RASSF6 Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 6
chr10_-_96271508 Show fit	0.91	ENST00000427367.6 ENST00000413476.6 ENST00000371176.6	BLNK Ensembl NCBI GeneCards UniProt Show fit	B cell linker
chr19_+_43716095 Show fit	0.90	ENST00000596627.1	IRGC Ensembl NCBI GeneCards UniProt Show fit	immunity related GTPase cinema
chr11_-_108222594 Show fit	0.90	ENST00000278612.9	NPAT Ensembl NCBI GeneCards UniProt Show fit	nuclear protein, coactivator of histone transcription
chr5_-_147831627 Show fit	0.89	ENST00000510027.2	SPINK1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor Kazal type 1
chr14_-_106658251 Show fit	0.88	ENST00000454421.2	IGHV3-64 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64
chr1_+_99646025 Show fit	0.87	ENST00000263174.9 ENST00000605497.5 ENST00000615664.1	PALMD Ensembl NCBI GeneCards UniProt Show fit	palmdelphin
chr3_+_1092654 Show fit	0.86	ENST00000350110.2	CNTN6 Ensembl NCBI GeneCards UniProt Show fit	contactin 6
chr22_-_45212431 Show fit	0.86	ENST00000496226.1 ENST00000251993.11	KIAA0930 Ensembl NCBI GeneCards UniProt Show fit	KIAA0930
chr16_-_21278282 Show fit	0.85	ENST00000572914.2	CRYM Ensembl NCBI GeneCards UniProt Show fit	crystallin mu
chr2_+_209579399 Show fit	0.83	ENST00000360351.8	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr9_-_90642791 Show fit	0.82	ENST00000375765.5 ENST00000636786.1	DIRAS2 Ensembl NCBI GeneCards UniProt Show fit	DIRAS family GTPase 2
chr16_+_81238682 Show fit	0.82	ENST00000258168.7 ENST00000564552.1	BCO1 Ensembl NCBI GeneCards UniProt Show fit	beta-carotene oxygenase 1
chr6_-_142147122 Show fit	0.81	ENST00000258042.2	NMBR Ensembl NCBI GeneCards UniProt Show fit	neuromedin B receptor
chr4_-_48012934 Show fit	0.80	ENST00000420489.7 ENST00000504722.6	CNGA1 Ensembl NCBI GeneCards UniProt Show fit	cyclic nucleotide gated channel subunit alpha 1
chr5_+_162067990 Show fit	0.80	ENST00000641017.1	GABRG2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2
chr19_-_57559833 Show fit	0.80	ENST00000457177.5	ZNF550 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 550
chr5_+_132658165 Show fit	0.79	ENST00000617259.2 ENST00000304506.7	IL13 Ensembl NCBI GeneCards UniProt Show fit	interleukin 13
chrX_-_43882411 Show fit	0.79	ENST00000378069.5	MAOB Ensembl NCBI GeneCards UniProt Show fit	monoamine oxidase B
chr4_+_26320975 Show fit	0.78	ENST00000509158.6 ENST00000681856.1 ENST00000680140.1 ENST00000355476.8 ENST00000680511.1	RBPJ Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr5_-_161546671 Show fit	0.76	ENST00000517547.5	GABRB2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit beta2
chr14_-_23010122 Show fit	0.76	ENST00000397377.5 ENST00000397379.7 ENST00000341470.8 ENST00000555998.5 ENST00000299088.11 ENST00000397376.6 ENST00000553675.5 ENST00000553931.5 ENST00000555575.5 ENST00000553958.5 ENST00000555098.5 ENST00000556419.5 ENST00000553606.5 ENST00000554179.5 ENST00000397382.8	C14orf93 Ensembl NCBI GeneCards UniProt Show fit	chromosome 14 open reading frame 93
chr2_+_33436304 Show fit	0.76	ENST00000402538.7	RASGRP3 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 3
chr1_-_15524344 Show fit	0.75	ENST00000348549.9 ENST00000546424.5	CASP9 Ensembl NCBI GeneCards UniProt Show fit	caspase 9
chr14_+_88594430 Show fit	0.75	ENST00000406216.7 ENST00000557737.1	ZC3H14 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 14
chrX_-_31266925 Show fit	0.74	ENST00000680557.1 ENST00000378680.6 ENST00000378723.7 ENST00000680768.2 ENST00000681870.1 ENST00000680355.1 ENST00000682322.1 ENST00000682600.1 ENST00000680162.2 ENST00000681153.1 ENST00000681334.1	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr9_-_21368057 Show fit	0.74	ENST00000449498.2	IFNA13 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 13
chr19_-_43026448 Show fit	0.73	ENST00000598133.1 ENST00000403486.5 ENST00000320078.12 ENST00000306322.7	PSG11 Ensembl NCBI GeneCards UniProt Show fit	pregnancy specific beta-1-glycoprotein 11
chr2_+_209579429 Show fit	0.73	ENST00000361559.8	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr13_+_19958708 Show fit	0.72	ENST00000382874.6 ENST00000610343.5	ZMYM2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger MYM-type containing 2
chr10_+_30434021 Show fit	0.71	ENST00000542547.5	MAP3K8 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr10_-_99235783 Show fit	0.71	ENST00000370546.5 ENST00000614306.1	HPSE2 Ensembl NCBI GeneCards UniProt Show fit	heparanase 2 (inactive)
chr8_+_30387064 Show fit	0.71	ENST00000523115.5 ENST00000519647.5	RBPMS Ensembl NCBI GeneCards UniProt Show fit	RNA binding protein, mRNA processing factor
chr13_+_19958760 Show fit	0.71	ENST00000382871.3	ZMYM2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger MYM-type containing 2
chr2_-_55334529 Show fit	0.70	ENST00000645860.1 ENST00000642563.1 ENST00000647396.1	CCDC88A Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr14_+_88594406 Show fit	0.69	ENST00000555900.5	ZC3H14 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 14
chr20_+_38805686 Show fit	0.68	ENST00000299824.6 ENST00000373331.2	PPP1R16B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 16B
chrX_-_15600953 Show fit	0.68	ENST00000679212.1 ENST00000679278.1 ENST00000678046.1 ENST00000252519.8	ACE2 Ensembl NCBI GeneCards UniProt Show fit	angiotensin I converting enzyme 2
chrX_-_33211540 Show fit	0.67	ENST00000357033.9	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chrX_-_136780925 Show fit	0.67	ENST00000250617.7	ARHGEF6 Ensembl NCBI GeneCards UniProt Show fit	Rac/Cdc42 guanine nucleotide exchange factor 6
chr1_+_15476099 Show fit	0.67	ENST00000375910.8	CELA2B Ensembl NCBI GeneCards UniProt Show fit	chymotrypsin like elastase 2B
chr9_-_91423819 Show fit	0.66	ENST00000297689.4	NFIL3 Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, interleukin 3 regulated
chr2_+_209579598 Show fit	0.66	ENST00000445941.5 ENST00000673860.1	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr11_+_11841953 Show fit	0.66	ENST00000527733.7 ENST00000399455.2	USP47 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 47
chr14_-_106117159 Show fit	0.65	ENST00000390601.3	IGHV3-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-11
chr9_-_89178810 Show fit	0.65	ENST00000375835.9	SHC3 Ensembl NCBI GeneCards UniProt Show fit	SHC adaptor protein 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	34.8	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
2.3	6.9	GO:0071139	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
2.0	11.9	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
1.8	7.3	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
1.8	5.5	GO:0036292	DNA rewinding(GO:0036292)
1.8	5.4	GO:0048687	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
1.7	13.6	GO:0061709	reticulophagy(GO:0061709)
0.9	6.4	GO:0060844	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.9	5.4	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.8	3.3	GO:2000639	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.8	6.6	GO:0001887	selenium compound metabolic process(GO:0001887)
0.8	11.0	GO:0043589	skin morphogenesis(GO:0043589)
0.7	2.9	GO:0060940	epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.7	6.4	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.5	3.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.5	6.1	GO:0008354	germ cell migration(GO:0008354)
0.5	1.9	GO:0031161	phosphatidylinositol catabolic process(GO:0031161)
0.5	2.8	GO:0007341	penetration of zona pellucida(GO:0007341)
0.5	2.4	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.5	2.3	GO:0061743	motor learning(GO:0061743)
0.4	2.0	GO:1903906	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.4	3.6	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.4	2.3	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.4	1.5	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.4	1.1	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.4	2.1	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.3	3.7	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3	2.5	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
0.3	1.9	GO:0002005	angiotensin catabolic process in blood(GO:0002005) angiotensin-mediated drinking behavior(GO:0003051)
0.3	6.5	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.3	4.5	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3	2.3	GO:2000229	pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.3	1.2	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.3	5.7	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3	2.8	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.3	1.1	GO:0036269	swimming behavior(GO:0036269)
0.2	2.2	GO:0007135	meiosis II(GO:0007135)
0.2	0.7	GO:0070844	misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.2	2.5	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.2	0.7	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2	1.1	GO:0014738	regulation of muscle hyperplasia(GO:0014738)
0.2	1.1	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2	2.6	GO:1904903	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.2	0.6	GO:0072233	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.2	0.6	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2	1.1	GO:0008218	bioluminescence(GO:0008218)
0.2	0.5	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2	7.5	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2	2.9	GO:0003334	keratinocyte development(GO:0003334)
0.2	1.6	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.6	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1	2.2	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.1	2.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	1.9	GO:0006776	vitamin A metabolic process(GO:0006776)
0.1	2.1	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.1	0.5	GO:0030035	microspike assembly(GO:0030035)
0.1	0.4	GO:0015798	myo-inositol transport(GO:0015798)
0.1	3.4	GO:0071420	cellular response to histamine(GO:0071420)
0.1	0.5	GO:0042369	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369) response to sodium phosphate(GO:1904383)
0.1	1.6	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	1.4	GO:0006552	leucine catabolic process(GO:0006552)
0.1	1.7	GO:0002158	osteoclast proliferation(GO:0002158)
0.1	1.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	0.7	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.1	0.8	GO:0014063	response to aluminum ion(GO:0010044) negative regulation of serotonin secretion(GO:0014063)
0.1	0.2	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.1	0.5	GO:0071895	odontoblast differentiation(GO:0071895)
0.1	8.5	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.1	1.4	GO:0015074	DNA integration(GO:0015074)
0.1	0.6	GO:0033504	floor plate development(GO:0033504)
0.1	1.0	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1	1.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	2.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	1.2	GO:0032025	response to cobalt ion(GO:0032025)
0.1	0.1	GO:0044254	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.1	0.9	GO:0033623	positive regulation of platelet activation(GO:0010572) regulation of integrin activation(GO:0033623)
0.1	4.3	GO:0006298	mismatch repair(GO:0006298)
0.1	3.2	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
0.1	1.3	GO:0002467	germinal center formation(GO:0002467)
0.1	4.8	GO:0001578	microtubule bundle formation(GO:0001578)
0.1	0.9	GO:0070327	lysine catabolic process(GO:0006554) thyroid hormone transport(GO:0070327)
0.1	1.2	GO:0044458	motile cilium assembly(GO:0044458)
0.1	2.5	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	1.4	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1	0.7	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	1.7	GO:0030517	negative regulation of axon extension(GO:0030517)
0.1	0.1	GO:0035962	response to interleukin-13(GO:0035962)
0.1	0.7	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	3.3	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.1	0.5	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.1	0.2	GO:2000176	regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0	1.8	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.6	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0	0.2	GO:0060374	positive regulation of neutrophil apoptotic process(GO:0033031) B cell chemotaxis(GO:0035754) mast cell differentiation(GO:0060374)
0.0	0.5	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	1.0	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	1.7	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.3	GO:0019255	UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.5	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	1.3	GO:0035640	exploration behavior(GO:0035640)
0.0	0.6	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.7	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.6	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.9	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.2	GO:0061316	canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.0	1.5	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	3.0	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.6	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	1.0	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	8.2	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	1.4	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.3	GO:0010737	protein kinase A signaling(GO:0010737)
0.0	0.5	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0031959	mineralocorticoid receptor signaling pathway(GO:0031959) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722)
0.0	0.1	GO:0002118	aggressive behavior(GO:0002118)
0.0	1.1	GO:0034694	response to prostaglandin(GO:0034694)
0.0	1.0	GO:0007618	mating(GO:0007618)
0.0	2.0	GO:0034113	heterotypic cell-cell adhesion(GO:0034113)
0.0	0.5	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.4	GO:2001204	regulation of osteoclast development(GO:2001204)
0.0	1.3	GO:0006026	aminoglycan catabolic process(GO:0006026) glycosaminoglycan catabolic process(GO:0006027)
0.0	2.9	GO:0007286	spermatid development(GO:0007286)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.3	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.9	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	1.2	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	1.4	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	1.4	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	0.9	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.4	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.7	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	1.2	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.2	GO:0055096	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0035691	macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.0	1.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	1.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	1.5	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.7	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.0	0.4	GO:2000772	regulation of cellular senescence(GO:2000772)
0.0	0.4	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.2	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.2	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	0.6	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	1.5	GO:0007586	digestion(GO:0007586)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	34.8	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.5	7.5	GO:0098843	postsynaptic endocytic zone(GO:0098843)
1.9	25.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.1	3.2	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.7	6.4	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5	3.3	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.5	3.6	GO:0034464	BBSome(GO:0034464)
0.4	4.3	GO:0032389	MutLalpha complex(GO:0032389)
0.4	3.3	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.4	1.2	GO:0097224	sperm connecting piece(GO:0097224)
0.4	3.6	GO:0071953	elastic fiber(GO:0071953)
0.4	1.2	GO:0043293	apoptosome(GO:0043293)
0.4	1.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.3	5.6	GO:0008091	spectrin(GO:0008091)
0.3	6.6	GO:0031089	platelet dense granule lumen(GO:0031089)
0.2	5.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.2	12.5	GO:0005801	cis-Golgi network(GO:0005801)
0.2	1.4	GO:1905202	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.2	0.5	GO:0071750	dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1	3.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	2.0	GO:0030478	actin cap(GO:0030478)
0.1	1.6	GO:0016013	syntrophin complex(GO:0016013)
0.1	0.5	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.1	0.9	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.1	1.7	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	5.0	GO:0043596	nuclear replication fork(GO:0043596)
0.1	0.3	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.1	2.9	GO:0016514	SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.1	3.5	GO:0005720	nuclear heterochromatin(GO:0005720)
0.1	1.0	GO:0098839	postsynaptic density membrane(GO:0098839)
0.1	1.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	1.4	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	3.1	GO:0032590	dendrite membrane(GO:0032590)
0.1	3.7	GO:0008305	integrin complex(GO:0008305)
0.1	1.0	GO:0043083	synaptic cleft(GO:0043083)
0.1	1.0	GO:0005883	neurofilament(GO:0005883)
0.1	3.0	GO:0002102	podosome(GO:0002102)
0.1	1.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	1.1	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.8	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.9	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	1.0	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.8	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.6	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.5	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	6.2	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0071821	FANCM-MHF complex(GO:0071821)
0.0	2.2	GO:0005844	polysome(GO:0005844)
0.0	6.8	GO:0030426	growth cone(GO:0030426)
0.0	0.5	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	2.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	3.3	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.2	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	1.1	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.4	GO:0000145	exocyst(GO:0000145)
0.0	0.6	GO:0043194	axon initial segment(GO:0043194)
0.0	0.7	GO:0005685	U1 snRNP(GO:0005685)
0.0	1.7	GO:0031256	leading edge membrane(GO:0031256)
0.0	1.5	GO:0030175	filopodium(GO:0030175)
0.0	1.8	GO:0031594	neuromuscular junction(GO:0031594)
0.0	2.2	GO:0036064	ciliary basal body(GO:0036064)
0.0	1.0	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	1.3	GO:0005581	collagen trimer(GO:0005581)
0.0	1.2	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	2.7	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.7	GO:0016235	aggresome(GO:0016235)
0.0	1.9	GO:0031461	cullin-RING ubiquitin ligase complex(GO:0031461)
0.0	3.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.4	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.6	GO:0097223	sperm part(GO:0097223)
0.0	2.5	GO:0043209	myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	23.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
1.2	7.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
1.1	3.3	GO:0035663	Toll-like receptor 4 binding(GO:0035662) Toll-like receptor 2 binding(GO:0035663)
1.0	6.9	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.9	7.5	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.9	2.7	GO:0004556	alpha-amylase activity(GO:0004556)
0.6	1.8	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.6	5.6	GO:0042731	PH domain binding(GO:0042731)
0.5	6.6	GO:0008430	selenium binding(GO:0008430)
0.5	6.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.5	5.5	GO:0036310	annealing helicase activity(GO:0036310)
0.5	5.4	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.5	41.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.5	6.4	GO:0000150	recombinase activity(GO:0000150)
0.4	9.1	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4	1.3	GO:0030305	heparanase activity(GO:0030305)
0.4	3.3	GO:0050816	phosphothreonine binding(GO:0050816)
0.4	4.0	GO:0008131	primary amine oxidase activity(GO:0008131)
0.4	1.2	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.4	1.9	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.4	1.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.3	1.7	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.3	3.7	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.3	0.9	GO:0042806	fucose binding(GO:0042806)
0.3	2.5	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.2	1.9	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2	4.9	GO:0002162	dystroglycan binding(GO:0002162)
0.2	0.9	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2	0.6	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.2	1.7	GO:0005549	odorant binding(GO:0005549)
0.2	1.4	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2	4.3	GO:0030983	mismatched DNA binding(GO:0030983)
0.2	0.7	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.2	1.6	GO:0050692	DBD domain binding(GO:0050692)
0.2	3.3	GO:0001056	RNA polymerase III activity(GO:0001056)
0.2	2.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	1.5	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1	0.7	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.1	2.0	GO:0045159	myosin II binding(GO:0045159)
0.1	0.7	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	2.9	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	1.2	GO:0032027	myosin light chain binding(GO:0032027)
0.1	1.5	GO:0030911	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.1	1.9	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	1.0	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1	2.2	GO:0008494	translation activator activity(GO:0008494)
0.1	0.5	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	0.6	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.5	GO:0019862	IgA binding(GO:0019862)
0.1	1.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	1.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	7.8	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	0.7	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.6	GO:0004111	creatine kinase activity(GO:0004111)
0.1	1.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	1.9	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	2.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.8	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1	1.4	GO:0005112	Notch binding(GO:0005112)
0.1	0.3	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1	0.6	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	2.0	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.2	GO:0055100	adiponectin binding(GO:0055100)
0.1	5.3	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	1.0	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.1	2.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	1.7	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	1.5	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.5	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.6	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	1.7	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.2	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0	0.7	GO:0043422	protein kinase B binding(GO:0043422)
0.0	1.3	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.8	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	1.1	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	1.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.3	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	2.1	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.0	0.7	GO:0008143	poly(A) binding(GO:0008143)
0.0	1.7	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	1.1	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.6	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.4	GO:0005537	mannose binding(GO:0005537)
0.0	0.6	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.8	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.4	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	1.0	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.6	GO:0071837	HMG box domain binding(GO:0071837)
0.0	2.7	GO:0008201	heparin binding(GO:0008201)
0.0	0.6	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.5	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	2.5	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.9	GO:0005518	collagen binding(GO:0005518)
0.0	1.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	2.5	GO:0044325	ion channel binding(GO:0044325)
0.0	1.1	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	44.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3	14.3	NABA COLLAGENS	Genes encoding collagen proteins
0.1	9.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	3.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	8.4	PID NOTCH PATHWAY	Notch signaling pathway
0.1	2.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	1.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	9.1	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	0.8	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	14.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	2.8	PID BARD1 PATHWAY	BARD1 signaling events
0.1	3.8	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	2.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	1.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	0.9	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	2.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	3.0	PID SHP2 PATHWAY	SHP2 signaling
0.0	2.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	4.3	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	2.1	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.9	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.8	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.8	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	3.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.2	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.5	PID FGF PATHWAY	FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	34.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.6	11.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.4	4.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.3	5.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.3	7.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	2.8	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	14.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	3.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.2	1.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	3.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	9.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	2.9	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	2.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	2.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	2.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	1.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	3.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	1.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	1.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	1.2	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	0.8	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	1.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	1.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.6	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	1.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	3.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	5.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	1.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	2.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.7	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.7	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	1.1	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	2.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism

Results for IKZF2

Z-value: 0.68

Motif logo

Transcription factors associated with IKZF2

Activity-expression correlation:

Activity profile of IKZF2 motif

Sorted Z-values of IKZF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: