Project
GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for KLF14_SP8
Z-value: 1.70
Motif logo
Transcription factors associated with KLF14_SP8
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF14_SP8
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_47256518 Show fit | 49.51 |
ENST00000643617.1
ENST00000221922.11 |
coiled-coil domain containing 9 |
|
| chr15_-_72118114 Show fit | 44.19 |
ENST00000356056.10
ENST00000569314.1 |
myosin IXA |
|
| chr7_-_4883683 Show fit | 43.99 |
ENST00000399583.4
|
Rap associating with DIL domain |
|
| chr6_-_33317728 Show fit | 42.18 |
ENST00000431845.3
|
zinc finger and BTB domain containing 22 |
|
| chr11_+_72080313 Show fit | 40.49 |
ENST00000307198.11
ENST00000538413.6 ENST00000642648.1 ENST00000289488.7 |
leucine rich transmembrane and O-methyltransferase domain containing leucine rich transmembrane and O-methyltransferase domain containing |
|
| chr11_+_72080595 Show fit | 39.15 |
ENST00000647530.1
ENST00000539271.6 ENST00000642510.1 |
leucine rich transmembrane and O-methyltransferase domain containing |
|
| chr16_-_46831134 Show fit | 38.14 |
ENST00000394806.6
ENST00000285697.9 |
chromosome 16 open reading frame 87 |
|
| chr10_+_102918344 Show fit | 37.89 |
ENST00000433628.2
|
cyclin and CBS domain divalent metal cation transport mediator 2 |
|
| chr15_+_72118392 Show fit | 36.78 |
ENST00000340912.6
|
SUMO peptidase family member, NEDD8 specific |
|
| chr19_-_55354703 Show fit | 35.79 |
ENST00000593184.5
ENST00000326529.9 ENST00000589467.1 |
cytochrome c oxidase subunit 6B2 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 149.2 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 1.6 | 118.2 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 5.1 | 96.8 | GO:0019614 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
| 4.3 | 73.7 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 3.5 | 59.8 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 1.5 | 53.7 | GO:0045187 | regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
| 6.6 | 53.2 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 6.0 | 42.1 | GO:1904100 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.7 | 39.3 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 1.4 | 38.2 | GO:0032011 | ARF protein signal transduction(GO:0032011) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.7 | 69.5 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 5.2 | 57.3 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 5.9 | 53.2 | GO:0090576 | RNA polymerase III transcription factor complex(GO:0090576) |
| 0.4 | 50.5 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 1.1 | 50.0 | GO:0097546 | ciliary base(GO:0097546) |
| 5.4 | 48.8 | GO:0001520 | outer dense fiber(GO:0001520) |
| 6.9 | 48.6 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 0.9 | 44.1 | GO:0016235 | aggresome(GO:0016235) |
| 4.1 | 37.1 | GO:0097427 | microtubule bundle(GO:0097427) |
| 1.1 | 36.8 | GO:0035861 | site of double-strand break(GO:0035861) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 262.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.2 | 242.0 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 10.8 | 96.8 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 4.3 | 73.7 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.8 | 68.0 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 2.0 | 64.9 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.7 | 60.7 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 13.3 | 53.2 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 5.7 | 40.2 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 7.4 | 37.0 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 67.4 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.9 | 58.4 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.4 | 41.1 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.6 | 35.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.6 | 34.7 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 1.0 | 32.5 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.2 | 31.8 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.8 | 31.6 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.5 | 31.2 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.4 | 29.4 | PID LKB1 PATHWAY | LKB1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 69.0 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 1.2 | 62.1 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 1.1 | 51.5 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 1.7 | 50.5 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.8 | 46.1 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.3 | 45.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 1.4 | 39.7 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.4 | 34.9 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 1.9 | 30.2 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.4 | 28.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |