ISMARA results: NR6A1

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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR6A1

Z-value: 0.98

Motif logo

Transcription factors associated with NR6A1

Gene Symbol	Gene ID	Gene Info
NR6A1 Ensembl NCBI GeneCards UniProt	ENSG00000148200.17	NR6A1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NR6A1	hg38_v1_chr9_-_124771304_124771337	0.51	8.0e-16	Click!

Activity profile of NR6A1 motif

Sorted Z-values of NR6A1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr14_-_106507476 Show fit	19.87	ENST00000390621.3	IGHV1-45 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-45
chr14_-_105626066 Show fit	18.76	ENST00000641978.1 ENST00000390543.3	IGHG4 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant gamma 4 (G4m marker)
chr14_-_105771405 Show fit	17.29	ENST00000641136.1 ENST00000390551.6	IGHG3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant gamma 3 (G3m marker)
chr21_-_10649835 Show fit	12.97	ENST00000622028.1	IGHV1OR21-1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr19_-_6720641 Show fit	12.77	ENST00000245907.11	C3 Ensembl NCBI GeneCards UniProt Show fit	complement C3
chr14_-_106185387 Show fit	12.43	ENST00000390605.2	IGHV1-18 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-18
chr12_-_91180365 Show fit	12.04	ENST00000547937.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr14_-_106715166 Show fit	10.58	ENST00000390633.2	IGHV1-69 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69
chr14_-_106762576 Show fit	10.39	ENST00000624687.1	IGHV1-69D Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69D
chr14_-_106737547 Show fit	10.13	ENST00000632209.1	IGHV1-69-2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69-2
chr22_+_22887780 Show fit	8.84	ENST00000532223.2 ENST00000526893.6 ENST00000531372.1	IGLL5 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda like polypeptide 5
chr15_-_21718245 Show fit	8.35	ENST00000630556.1	ENSG00000281179.1 Ensembl NCBI GeneCards UniProt Show fit	novel gene identicle to IGHV1OR15-1
chr14_-_106277039 Show fit	7.79	ENST00000390610.2	IGHV1-24 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-24
chr17_-_40937445 Show fit	7.74	ENST00000436344.7 ENST00000485751.1	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23
chr7_-_150341615 Show fit	7.63	ENST00000223271.8 ENST00000466675.5 ENST00000482669.1 ENST00000467793.5	RARRES2 Ensembl NCBI GeneCards UniProt Show fit	retinoic acid receptor responder 2
chr22_+_22720615 Show fit	6.87	ENST00000390309.2	IGLV3-19 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-19
chr19_-_11559145 Show fit	6.86	ENST00000589171.5 ENST00000590700.5 ENST00000586683.5 ENST00000593077.1 ENST00000252445.7	ELOF1 Ensembl NCBI GeneCards UniProt Show fit	elongation factor 1 homolog
chr17_-_40937641 Show fit	6.76	ENST00000209718.8	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23
chr5_-_41213505 Show fit	6.76	ENST00000337836.10 ENST00000433294.1	C6 Ensembl NCBI GeneCards UniProt Show fit	complement C6
chr19_+_41877267 Show fit	6.73	ENST00000221972.8 ENST00000597454.1 ENST00000444740.2	CD79A Ensembl NCBI GeneCards UniProt Show fit	CD79a molecule
chr16_-_75464364 Show fit	5.95	ENST00000569540.5 ENST00000566594.1	TMEM170A Ensembl NCBI GeneCards UniProt Show fit ENSG00000261717.5 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 170A novel TMEM170A-CFDP1 readthrough protein
chr19_+_3933059 Show fit	5.94	ENST00000616156.4 ENST00000168977.6 ENST00000599576.5	NMRK2 Ensembl NCBI GeneCards UniProt Show fit	nicotinamide riboside kinase 2
chr8_+_102551583 Show fit	5.88	ENST00000285402.4	ODF1 Ensembl NCBI GeneCards UniProt Show fit	outer dense fiber of sperm tails 1
chr14_-_95714088 Show fit	5.85	ENST00000556450.5	TCL1A Ensembl NCBI GeneCards UniProt Show fit	TCL1 family AKT coactivator A
chr6_+_31652414 Show fit	5.80	ENST00000375918.6 ENST00000375920.8	APOM Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein M
chr5_-_139389905 Show fit	5.76	ENST00000302125.9	MZB1 Ensembl NCBI GeneCards UniProt Show fit	marginal zone B and B1 cell specific protein
chr9_+_128455180 Show fit	5.72	ENST00000497812.6 ENST00000393533.6	ODF2 Ensembl NCBI GeneCards UniProt Show fit	outer dense fiber of sperm tails 2
chr14_-_46651753 Show fit	5.66	ENST00000298283.5	RPL10L Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L10 like
chr16_-_75464655 Show fit	5.59	ENST00000569276.1 ENST00000357613.8 ENST00000561878.2 ENST00000566980.1 ENST00000567194.5	TMEM170A Ensembl NCBI GeneCards UniProt Show fit ENSG00000261717.5 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 170A novel TMEM170A-CFDP1 readthrough protein
chr8_-_27614681 Show fit	5.58	ENST00000519472.5 ENST00000523589.5 ENST00000522413.5 ENST00000523396.1 ENST00000316403.15	CLU Ensembl NCBI GeneCards UniProt Show fit	clusterin
chr14_-_95714146 Show fit	5.55	ENST00000554012.5	TCL1A Ensembl NCBI GeneCards UniProt Show fit	TCL1 family AKT coactivator A
chr14_-_95714114 Show fit	5.41	ENST00000402399.6 ENST00000555202.1	TCL1A Ensembl NCBI GeneCards UniProt Show fit	TCL1 family AKT coactivator A
chr8_-_144475808 Show fit	5.25	ENST00000377317.5	FOXH1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box H1
chr3_-_115071333 Show fit	5.22	ENST00000462705.5	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr19_+_3933581 Show fit	5.17	ENST00000593949.1	NMRK2 Ensembl NCBI GeneCards UniProt Show fit	nicotinamide riboside kinase 2
chr21_+_42219123 Show fit	5.12	ENST00000398449.8	ABCG1 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily G member 1
chr5_-_131635030 Show fit	5.06	ENST00000308008.10 ENST00000296859.10 ENST00000627212.2 ENST00000507093.5 ENST00000509018.6 ENST00000510071.5	RAPGEF6 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 6
chr20_+_45174894 Show fit	4.83	ENST00000243924.4	PI3 Ensembl NCBI GeneCards UniProt Show fit	peptidase inhibitor 3
chr17_+_47733228 Show fit	4.61	ENST00000177694.2	TBX21 Ensembl NCBI GeneCards UniProt Show fit	T-box transcription factor 21
chr13_+_23180960 Show fit	4.59	ENST00000218867.4	SGCG Ensembl NCBI GeneCards UniProt Show fit	sarcoglycan gamma
chr19_+_49496424 Show fit	4.56	ENST00000596873.1 ENST00000594493.1 ENST00000270625.7 ENST00000599561.1	RPS11 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S11
chr2_-_60553618 Show fit	4.35	ENST00000643716.1 ENST00000359629.10 ENST00000642384.2 ENST00000335712.11	BCL11A Ensembl NCBI GeneCards UniProt Show fit	BAF chromatin remodeling complex subunit BCL11A
chr1_-_206921867 Show fit	4.35	ENST00000628511.2 ENST00000367091.8	FCMR Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgM receptor
chr1_+_151766655 Show fit	4.30	ENST00000400999.7	OAZ3 Ensembl NCBI GeneCards UniProt Show fit	ornithine decarboxylase antizyme 3
chr19_-_344786 Show fit	4.25	ENST00000264819.7	MIER2 Ensembl NCBI GeneCards UniProt Show fit	MIER family member 2
chr19_-_22010930 Show fit	4.19	ENST00000601773.5 ENST00000397126.9 ENST00000609966.5 ENST00000601993.1 ENST00000599916.5	ZNF208 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 208
chr6_+_31946086 Show fit	4.14	ENST00000425368.7	CFB Ensembl NCBI GeneCards UniProt Show fit	complement factor B
chr2_-_25341886 Show fit	4.07	ENST00000321117.10	DNMT3A Ensembl NCBI GeneCards UniProt Show fit	DNA methyltransferase 3 alpha
chr12_+_10929229 Show fit	4.07	ENST00000381847.7 ENST00000396400.4	PRH2 Ensembl NCBI GeneCards UniProt Show fit	proline rich protein HaeIII subfamily 2
chr17_-_39152571 Show fit	4.06	ENST00000415163.5 ENST00000441877.5 ENST00000444911.6	PLXDC1 Ensembl NCBI GeneCards UniProt Show fit	plexin domain containing 1
chr1_+_225810057 Show fit	4.05	ENST00000272167.10 ENST00000448202.5	EPHX1 Ensembl NCBI GeneCards UniProt Show fit	epoxide hydrolase 1
chr17_+_50426210 Show fit	4.04	ENST00000506582.5 ENST00000504392.5 ENST00000300441.9 ENST00000427954.6	ACSF2 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase family member 2
chr1_-_20508095 Show fit	3.93	ENST00000264198.5	MUL1 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial E3 ubiquitin protein ligase 1
chr7_+_72879349 Show fit	3.86	ENST00000395270.5	POM121 Ensembl NCBI GeneCards UniProt Show fit	POM121 transmembrane nucleoporin
chr11_+_113314569 Show fit	3.86	ENST00000429951.5 ENST00000442859.5 ENST00000531164.5 ENST00000529850.5 ENST00000529221.6 ENST00000525965.5	TTC12 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 12
chr1_+_1324790 Show fit	3.81	ENST00000343938.9	CPTP Ensembl NCBI GeneCards UniProt Show fit	ceramide-1-phosphate transfer protein
chr9_+_121207774 Show fit	3.77	ENST00000373823.7	GSN Ensembl NCBI GeneCards UniProt Show fit	gelsolin
chr5_-_75052546 Show fit	3.76	ENST00000652361.2	GCNT4 Ensembl NCBI GeneCards UniProt Show fit	glucosaminyl (N-acetyl) transferase 4
chr22_+_22594528 Show fit	3.66	ENST00000390303.3	IGLV3-32 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-32 (non-functional)
chr7_+_156949704 Show fit	3.62	ENST00000275820.4	NOM1 Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein with MIF4G domain 1
chr1_+_119414931 Show fit	3.60	ENST00000543831.5 ENST00000433745.5 ENST00000369416.4	HSD3B2 Ensembl NCBI GeneCards UniProt Show fit	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr9_+_131009141 Show fit	3.53	ENST00000361069.9	LAMC3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit gamma 3
chr1_+_78045956 Show fit	3.52	ENST00000370759.4	GIPC2 Ensembl NCBI GeneCards UniProt Show fit	GIPC PDZ domain containing family member 2
chr14_-_75981986 Show fit	3.52	ENST00000238682.8	TGFB3 Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta 3
chr1_-_23177683 Show fit	3.51	ENST00000302291.8	LUZP1 Ensembl NCBI GeneCards UniProt Show fit	leucine zipper protein 1
chr17_+_7627963 Show fit	3.49	ENST00000575729.5 ENST00000340624.9	SHBG Ensembl NCBI GeneCards UniProt Show fit	sex hormone binding globulin
chr14_-_99272184 Show fit	3.41	ENST00000357195.8	BCL11B Ensembl NCBI GeneCards UniProt Show fit	BAF chromatin remodeling complex subunit BCL11B
chr6_-_168093012 Show fit	3.40	ENST00000646385.1	FRMD1 Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 1
chr14_-_106005574 Show fit	3.40	ENST00000390595.3	IGHV1-3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-3
chr19_+_49487510 Show fit	3.38	ENST00000679106.1 ENST00000621674.4 ENST00000391857.9 ENST00000678510.1 ENST00000467825.2	RPL13A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L13a
chr7_+_150824603 Show fit	3.33	ENST00000493429.5	AOC1 Ensembl NCBI GeneCards UniProt Show fit	amine oxidase copper containing 1
chr17_+_50426242 Show fit	3.33	ENST00000502667.5	ACSF2 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase family member 2
chr3_-_49120887 Show fit	3.31	ENST00000453664.5 ENST00000398888.6	USP19 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 19
chr1_+_156369202 Show fit	3.31	ENST00000537040.6	RHBG Ensembl NCBI GeneCards UniProt Show fit	Rh family B glycoprotein
chr19_-_9621195 Show fit	3.28	ENST00000424629.5 ENST00000326044.9 ENST00000435550.5 ENST00000302851.8 ENST00000444611.5 ENST00000421525.5	ZNF561 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 561
chr12_-_12338674 Show fit	3.24	ENST00000545735.1	MANSC1 Ensembl NCBI GeneCards UniProt Show fit	MANSC domain containing 1
chr9_-_21351378 Show fit	3.24	ENST00000380210.1	IFNA6 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 6
chr7_+_100602344 Show fit	3.20	ENST00000223061.6	PCOLCE Ensembl NCBI GeneCards UniProt Show fit	procollagen C-endopeptidase enhancer
chr1_-_153544997 Show fit	3.19	ENST00000368715.5	S100A4 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A4
chr11_-_18248662 Show fit	3.14	ENST00000256733.9	SAA2 Ensembl NCBI GeneCards UniProt Show fit	serum amyloid A2
chr8_-_27611325 Show fit	3.10	ENST00000523500.5	CLU Ensembl NCBI GeneCards UniProt Show fit	clusterin
chr11_-_6440980 Show fit	3.08	ENST00000265983.8 ENST00000615166.1	HPX Ensembl NCBI GeneCards UniProt Show fit	hemopexin
chr12_+_2812638 Show fit	3.05	ENST00000228799.7	ITFG2 Ensembl NCBI GeneCards UniProt Show fit	integrin alpha FG-GAP repeat containing 2
chr1_-_207051202 Show fit	3.04	ENST00000315927.9	YOD1 Ensembl NCBI GeneCards UniProt Show fit	YOD1 deubiquitinase
chr6_+_106086316 Show fit	3.02	ENST00000369091.6 ENST00000369096.9	PRDM1 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 1
chr2_-_162074050 Show fit	3.00	ENST00000676768.1	DPP4 Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl peptidase 4
chr3_+_37243333 Show fit	2.98	ENST00000431105.1	GOLGA4 Ensembl NCBI GeneCards UniProt Show fit	golgin A4
chr1_+_45913647 Show fit	2.98	ENST00000674079.1	MAST2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase 2
chr7_-_101200912 Show fit	2.95	ENST00000440203.6 ENST00000379423.3 ENST00000223114.9	MOGAT3 Ensembl NCBI GeneCards UniProt Show fit	monoacylglycerol O-acyltransferase 3
chr17_-_2711736 Show fit	2.93	ENST00000651024.2 ENST00000576885.5 ENST00000574426.7	CLUH Ensembl NCBI GeneCards UniProt Show fit	clustered mitochondria homolog
chr6_+_128883114 Show fit	2.91	ENST00000421865.3 ENST00000618192.4 ENST00000617695.4	LAMA2 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 2
chr1_-_158686700 Show fit	2.91	ENST00000643759.2	SPTA1 Ensembl NCBI GeneCards UniProt Show fit	spectrin alpha, erythrocytic 1
chr11_+_113314811 Show fit	2.87	ENST00000393020.5	TTC12 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 12
chr8_-_27611424 Show fit	2.87	ENST00000405140.7	CLU Ensembl NCBI GeneCards UniProt Show fit	clusterin
chr1_+_162069674 Show fit	2.85	ENST00000361897.10	NOS1AP Ensembl NCBI GeneCards UniProt Show fit	nitric oxide synthase 1 adaptor protein
chr11_-_64744811 Show fit	2.82	ENST00000377497.7 ENST00000377487.5 ENST00000430645.1	RASGRP2 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 2
chr4_+_39182497 Show fit	2.81	ENST00000509560.5 ENST00000512112.5 ENST00000399820.8 ENST00000506503.1	WDR19 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 19
chrX_-_6535118 Show fit	2.80	ENST00000381089.7 ENST00000612369.4 ENST00000398729.1	VCX3A Ensembl NCBI GeneCards UniProt Show fit	variable charge X-linked 3A
chr1_-_160647037 Show fit	2.76	ENST00000302035.11	SLAMF1 Ensembl NCBI GeneCards UniProt Show fit	signaling lymphocytic activation molecule family member 1
chr3_-_194351290 Show fit	2.75	ENST00000429275.1 ENST00000323830.4	CPN2 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase N subunit 2
chr3_+_122184233 Show fit	2.72	ENST00000638421.1 ENST00000498619.4	CASR Ensembl NCBI GeneCards UniProt Show fit	calcium sensing receptor
chr16_-_3400963 Show fit	2.70	ENST00000571906.1 ENST00000573830.1 ENST00000439568.2 ENST00000396852.9 ENST00000422427.6 ENST00000304926.7 ENST00000618425.4 ENST00000396846.8	ZSCAN32 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and SCAN domain containing 32
chr7_+_94907584 Show fit	2.68	ENST00000433360.6 ENST00000340694.8 ENST00000424654.5	PPP1R9A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 9A
chr6_+_28141830 Show fit	2.68	ENST00000330236.7	ZKSCAN8 Ensembl NCBI GeneCards UniProt Show fit	zinc finger with KRAB and SCAN domains 8
chr15_+_100879822 Show fit	2.68	ENST00000329841.10 ENST00000557963.1 ENST00000346623.6	ALDH1A3 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family member A3
chr10_-_68332914 Show fit	2.67	ENST00000358769.7 ENST00000495025.2	PBLD Ensembl NCBI GeneCards UniProt Show fit	phenazine biosynthesis like protein domain containing
chr16_+_31117656 Show fit	2.64	ENST00000219797.9 ENST00000448516.6	KAT8 Ensembl NCBI GeneCards UniProt Show fit	lysine acetyltransferase 8
chr1_-_160647287 Show fit	2.61	ENST00000235739.6	SLAMF1 Ensembl NCBI GeneCards UniProt Show fit	signaling lymphocytic activation molecule family member 1
chrX_+_22032301 Show fit	2.60	ENST00000379374.5	PHEX Ensembl NCBI GeneCards UniProt Show fit	phosphate regulating endopeptidase homolog X-linked
chr1_-_202710428 Show fit	2.60	ENST00000367268.5	SYT2 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin 2
chrX_+_8464830 Show fit	2.60	ENST00000453306.4 ENST00000381032.6 ENST00000444481.3	VCX3B Ensembl NCBI GeneCards UniProt Show fit	variable charge X-linked 3B
chr2_+_68774782 Show fit	2.58	ENST00000409030.7 ENST00000409220.5	ARHGAP25 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 25
chr1_+_19596960 Show fit	2.55	ENST00000617872.4 ENST00000322753.7 ENST00000602662.1	MICOS10 Ensembl NCBI GeneCards UniProt Show fit NBL1 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial contact site and cristae organizing system subunit 10 NBL1, DAN family BMP antagonist
chr1_-_48400826 Show fit	2.53	ENST00000371841.1	SPATA6 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 6
chr9_-_127916978 Show fit	2.51	ENST00000361444.3 ENST00000335791.10	ST6GALNAC4 Ensembl NCBI GeneCards UniProt Show fit	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr1_-_161132659 Show fit	2.51	ENST00000368006.8 ENST00000490843.6 ENST00000545495.5	DEDD Ensembl NCBI GeneCards UniProt Show fit	death effector domain containing
chr22_-_42144549 Show fit	2.50	ENST00000614967.4 ENST00000612115.1	CYP2D7 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)
chr5_-_113294895 Show fit	2.49	ENST00000514701.5 ENST00000302475.8	MCC Ensembl NCBI GeneCards UniProt Show fit	MCC regulator of WNT signaling pathway
chr15_+_40765620 Show fit	2.49	ENST00000558467.1	GCHFR Ensembl NCBI GeneCards UniProt Show fit	GTP cyclohydrolase I feedback regulator
chr3_+_72996786 Show fit	2.48	ENST00000356692.10 ENST00000488810.5	PPP4R2 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 4 regulatory subunit 2
chr6_-_52909666 Show fit	2.45	ENST00000370968.5 ENST00000211122.4	GSTA3 Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase alpha 3
chr2_+_218710821 Show fit	2.45	ENST00000392102.6 ENST00000457313.5 ENST00000415717.5	TTLL4 Ensembl NCBI GeneCards UniProt Show fit	tubulin tyrosine ligase like 4
chr1_-_154956086 Show fit	2.45	ENST00000368463.8 ENST00000368460.7 ENST00000368465.5	PBXIP1 Ensembl NCBI GeneCards UniProt Show fit	PBX homeobox interacting protein 1
chrX_-_119693150 Show fit	2.44	ENST00000394610.7	SEPTIN6 Ensembl NCBI GeneCards UniProt Show fit	septin 6
chr21_+_42219111 Show fit	2.42	ENST00000450121.5 ENST00000361802.6	ABCG1 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily G member 1
chr1_+_110873135 Show fit	2.42	ENST00000271324.6	CD53 Ensembl NCBI GeneCards UniProt Show fit	CD53 molecule
chr1_+_162069768 Show fit	2.40	ENST00000530878.5	NOS1AP Ensembl NCBI GeneCards UniProt Show fit	nitric oxide synthase 1 adaptor protein
chr3_-_49120785 Show fit	2.39	ENST00000417901.5 ENST00000306026.5 ENST00000434032.6	USP19 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 19
chr10_+_122112957 Show fit	2.35	ENST00000369001.5	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr12_+_18242955 Show fit	2.33	ENST00000676171.1	PIK3C2G Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr7_+_142598016 Show fit	2.31	ENST00000620773.1	TRBV16 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 16
chr16_+_30748241 Show fit	2.29	ENST00000565924.5 ENST00000424889.7	PHKG2 Ensembl NCBI GeneCards UniProt Show fit	phosphorylase kinase catalytic subunit gamma 2
chr7_+_102363874 Show fit	2.29	ENST00000496391.5	PRKRIP1 Ensembl NCBI GeneCards UniProt Show fit	PRKR interacting protein 1
chr11_-_18248632 Show fit	2.28	ENST00000524555.3 ENST00000528349.5 ENST00000526900.1 ENST00000529528.5 ENST00000414546.6	SAA2-SAA4 Ensembl NCBI GeneCards UniProt Show fit SAA2 Ensembl NCBI GeneCards UniProt Show fit	SAA2-SAA4 readthrough serum amyloid A2
chr16_+_3401184 Show fit	2.28	ENST00000268655.5 ENST00000575752.5 ENST00000571936.5 ENST00000344823.9	ZNF174 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 174
chr3_-_139389604 Show fit	2.25	ENST00000515006.5 ENST00000510181.6 ENST00000333188.10 ENST00000513274.5 ENST00000514508.2 ENST00000503326.6 ENST00000507777.6 ENST00000512242.6 ENST00000512153.5 ENST00000512309.2	COPB2 Ensembl NCBI GeneCards UniProt Show fit	COPI coat complex subunit beta 2
chr11_+_62242232 Show fit	2.22	ENST00000244926.4	SCGB1D2 Ensembl NCBI GeneCards UniProt Show fit	secretoglobin family 1D member 2
chr11_+_66546896 Show fit	2.22	ENST00000513398.2	ACTN3 Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 3
chr2_+_33476640 Show fit	2.19	ENST00000425210.5 ENST00000444784.5 ENST00000423159.5 ENST00000403687.8	RASGRP3 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 3
chr6_-_31652678 Show fit	2.17	ENST00000437771.5 ENST00000362049.10 ENST00000439687.6 ENST00000211379.9 ENST00000375964.11 ENST00000676571.1 ENST00000676615.1	BAG6 Ensembl NCBI GeneCards UniProt Show fit	BAG cochaperone 6
chr16_-_3256587 Show fit	2.17	ENST00000536379.5 ENST00000541159.5 ENST00000339854.8 ENST00000219596.6	MEFV Ensembl NCBI GeneCards UniProt Show fit	MEFV innate immuity regulator, pyrin
chr2_+_233760265 Show fit	2.14	ENST00000305208.10 ENST00000360418.4	UGT1A1 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A1
chr11_-_1762403 Show fit	2.04	ENST00000367196.4	CTSD Ensembl NCBI GeneCards UniProt Show fit	cathepsin D
chr2_-_128318860 Show fit	2.02	ENST00000259241.7	HS6ST1 Ensembl NCBI GeneCards UniProt Show fit	heparan sulfate 6-O-sulfotransferase 1
chr6_+_32038382 Show fit	2.01	ENST00000478281.5 ENST00000471671.4 ENST00000435122.3 ENST00000644719.2	CYP21A2 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 21 subfamily A member 2
chr4_+_127781815 Show fit	2.00	ENST00000508776.5	HSPA4L Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family A (Hsp70) member 4 like
chr1_-_161132577 Show fit	1.98	ENST00000464113.1	DEDD Ensembl NCBI GeneCards UniProt Show fit	death effector domain containing
chr16_+_30748378 Show fit	1.89	ENST00000563588.6 ENST00000328273.11	PHKG2 Ensembl NCBI GeneCards UniProt Show fit	phosphorylase kinase catalytic subunit gamma 2
chr12_-_7109176 Show fit	1.87	ENST00000545280.5 ENST00000543933.5 ENST00000545337.1 ENST00000266542.9 ENST00000544702.5	C1RL Ensembl NCBI GeneCards UniProt Show fit	complement C1r subcomponent like
chr10_+_112375196 Show fit	1.86	ENST00000393081.6	ACSL5 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long chain family member 5
chr22_+_39994926 Show fit	1.86	ENST00000333407.11	FAM83F Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 83 member F
chr2_+_69013337 Show fit	1.86	ENST00000463335.2	ANTXR1 Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr6_-_31652358 Show fit	1.82	ENST00000456622.5 ENST00000435080.5 ENST00000375976.8 ENST00000441054.5	BAG6 Ensembl NCBI GeneCards UniProt Show fit	BAG cochaperone 6
chr4_+_673518 Show fit	1.82	ENST00000506838.5	MYL5 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 5
chr7_+_99828010 Show fit	1.80	ENST00000631161.2 ENST00000354829.7 ENST00000342499.8 ENST00000417625.5 ENST00000415413.5 ENST00000444905.5 ENST00000222382.5 ENST00000312017.9	CYP3A43 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 3 subfamily A member 43
chr3_+_185328886 Show fit	1.79	ENST00000428617.1 ENST00000443863.5	MAP3K13 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 13
chr10_+_87659839 Show fit	1.78	ENST00000456849.2	PAPSS2 Ensembl NCBI GeneCards UniProt Show fit	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr16_-_21159441 Show fit	1.78	ENST00000261383.3	DNAH3 Ensembl NCBI GeneCards UniProt Show fit	dynein axonemal heavy chain 3
chr1_-_161238163 Show fit	1.77	ENST00000367982.8	NR1I3 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group I member 3
chrX_+_47370578 Show fit	1.75	ENST00000377073.4	ZNF157 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 157
chr16_+_31074390 Show fit	1.74	ENST00000300850.5 ENST00000564189.1 ENST00000428260.1	ZNF646 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 646
chr17_+_50634845 Show fit	1.71	ENST00000427699.5 ENST00000285238.13	ABCC3 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily C member 3
chr9_-_14314067 Show fit	1.69	ENST00000397575.7	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr20_-_36773720 Show fit	1.68	ENST00000373740.7 ENST00000426836.5 ENST00000448110.6 ENST00000373750.9 ENST00000438549.5 ENST00000447406.1 ENST00000373734.8	DSN1 Ensembl NCBI GeneCards UniProt Show fit	DSN1 component of MIS12 kinetochore complex
chr1_+_212565334 Show fit	1.67	ENST00000366981.8 ENST00000366987.6	ATF3 Ensembl NCBI GeneCards UniProt Show fit	activating transcription factor 3
chr7_-_27152561 Show fit	1.66	ENST00000467897.2 ENST00000612286.5 ENST00000498652.1	ENSG00000273433.1 Ensembl NCBI GeneCards UniProt Show fit HOXA3 Ensembl NCBI GeneCards UniProt Show fit ENSG00000272801.1 Ensembl NCBI GeneCards UniProt Show fit	novel transcript homeobox A3 novel transcript
chr9_-_21350956 Show fit	1.66	ENST00000259555.5	IFNA6 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha 6
chr19_-_15934521 Show fit	1.62	ENST00000402119.9	CYP4F11 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 4 subfamily F member 11
chr2_+_218710931 Show fit	1.61	ENST00000442769.5 ENST00000424644.1	TTLL4 Ensembl NCBI GeneCards UniProt Show fit	tubulin tyrosine ligase like 4
chr7_-_137846860 Show fit	1.60	ENST00000288490.9 ENST00000614521.2 ENST00000424189.6 ENST00000446122.5	DGKI Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase iota
chr19_-_43186527 Show fit	1.60	ENST00000366175.7 ENST00000342951.11	PSG5 Ensembl NCBI GeneCards UniProt Show fit	pregnancy specific beta-1-glycoprotein 5
chr9_-_14313843 Show fit	1.59	ENST00000636063.1 ENST00000380921.3 ENST00000622520.1 ENST00000380959.7	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr19_-_10335773 Show fit	1.59	ENST00000592439.1	ICAM3 Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr1_-_203229660 Show fit	1.58	ENST00000255427.7 ENST00000367229.6	CHIT1 Ensembl NCBI GeneCards UniProt Show fit	chitinase 1
chr2_-_60553558 Show fit	1.58	ENST00000642439.1 ENST00000356842.9	BCL11A Ensembl NCBI GeneCards UniProt Show fit	BAF chromatin remodeling complex subunit BCL11A
chr16_-_48610150 Show fit	1.58	ENST00000262384.4	N4BP1 Ensembl NCBI GeneCards UniProt Show fit	NEDD4 binding protein 1
chr12_-_53200443 Show fit	1.58	ENST00000550743.6	ITGB7 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 7
chr6_-_25874212 Show fit	1.58	ENST00000361703.10 ENST00000397060.8	SLC17A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 member 3
chr3_+_171843337 Show fit	1.58	ENST00000334567.9 ENST00000619900.4 ENST00000450693.1	TMEM212 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 212
chr2_+_69013414 Show fit	1.57	ENST00000681816.1 ENST00000482235.2	ANTXR1 Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr10_+_68721207 Show fit	1.57	ENST00000538031.5 ENST00000543719.5 ENST00000539539.5 ENST00000265872.11 ENST00000543225.5 ENST00000536012.5 ENST00000494903.2	CCAR1 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle and apoptosis regulator 1
chr1_-_161238085 Show fit	1.54	ENST00000512372.5 ENST00000437437.6 ENST00000412844.6 ENST00000428574.6 ENST00000442691.6 ENST00000505005.5 ENST00000508740.5 ENST00000367981.7 ENST00000502985.5 ENST00000504010.5 ENST00000508387.5 ENST00000511676.5 ENST00000511748.5 ENST00000511944.5 ENST00000515621.5 ENST00000367984.8 ENST00000367985.7	NR1I3 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group I member 3
chr14_+_88563088 Show fit	1.54	ENST00000393514.9	ZC3H14 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 14
chr12_+_9827472 Show fit	1.54	ENST00000617793.4 ENST00000617889.5 ENST00000354855.7 ENST00000279545.7	KLRF1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin like receptor F1
chr19_-_14518383 Show fit	1.54	ENST00000254322.3 ENST00000595139.2	DNAJB1 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B1
chrX_-_139642889 Show fit	1.52	ENST00000370576.9	MCF2 Ensembl NCBI GeneCards UniProt Show fit	MCF.2 cell line derived transforming sequence
chr17_-_2711633 Show fit	1.52	ENST00000435359.5	CLUH Ensembl NCBI GeneCards UniProt Show fit	clustered mitochondria homolog
chr11_-_64744102 Show fit	1.50	ENST00000431822.5 ENST00000394432.8 ENST00000377486.7	RASGRP2 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 2
chr4_-_185810894 Show fit	1.49	ENST00000448662.6 ENST00000439049.5 ENST00000420158.5 ENST00000319471.13	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr20_-_31722533 Show fit	1.48	ENST00000677194.1 ENST00000434194.2 ENST00000376062.6	BCL2L1 Ensembl NCBI GeneCards UniProt Show fit	BCL2 like 1
chr1_-_161238196 Show fit	1.48	ENST00000367983.9 ENST00000506209.5 ENST00000367980.6 ENST00000628566.2	NR1I3 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group I member 3
chr11_-_112086727 Show fit	1.48	ENST00000504148.3 ENST00000541231.1	TIMM8B Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 8 homolog B
chr17_+_50165990 Show fit	1.47	ENST00000262018.8 ENST00000344627.10 ENST00000682109.1 ENST00000504073.2	SGCA Ensembl NCBI GeneCards UniProt Show fit	sarcoglycan alpha
chr7_+_143288215 Show fit	1.46	ENST00000619992.4 ENST00000310447.10	CASP2 Ensembl NCBI GeneCards UniProt Show fit	caspase 2
chr1_-_147773341 Show fit	1.46	ENST00000430508.1 ENST00000621517.1	GJA5 Ensembl NCBI GeneCards UniProt Show fit	gap junction protein alpha 5
chr11_-_74009077 Show fit	1.45	ENST00000314032.9 ENST00000426995.2	UCP3 Ensembl NCBI GeneCards UniProt Show fit	uncoupling protein 3
chr19_-_10569022 Show fit	1.42	ENST00000335766.2	CDKN2D Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 2D
chrX_-_8171267 Show fit	1.41	ENST00000317103.5	VCX2 Ensembl NCBI GeneCards UniProt Show fit	variable charge X-linked 2
chr7_-_6009072 Show fit	1.39	ENST00000642456.1 ENST00000642292.1 ENST00000441476.6	PMS2 Ensembl NCBI GeneCards UniProt Show fit	PMS1 homolog 2, mismatch repair system component
chr2_+_69013170 Show fit	1.39	ENST00000303714.9	ANTXR1 Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.9	19.5	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
2.5	7.6	GO:0061760	antifungal innate immune response(GO:0061760)
2.5	7.5	GO:0009720	detection of hormone stimulus(GO:0009720)
2.3	11.5	GO:1902847	regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.9	5.8	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
1.8	5.4	GO:0035744	T-helper 1 cell cytokine production(GO:0035744)
1.5	5.9	GO:1904800	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
1.5	5.8	GO:0034444	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
1.4	107.8	GO:0006910	phagocytosis, recognition(GO:0006910)
1.4	4.3	GO:0015847	putrescine transport(GO:0015847)
1.3	6.7	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
1.3	4.0	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
1.3	5.3	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
1.3	5.2	GO:1903116	positive regulation of actin filament-based movement(GO:1903116) positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
1.2	3.5	GO:1905073	uterine wall breakdown(GO:0042704) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.1	3.4	GO:0097534	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
1.1	16.8	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
1.1	3.3	GO:0070634	transepithelial ammonium transport(GO:0070634)
1.0	3.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
1.0	3.0	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
1.0	3.0	GO:1990654	regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
1.0	3.8	GO:0035627	ceramide transport(GO:0035627)
0.9	12.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.9	2.7	GO:1904049	negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.9	2.7	GO:0060166	olfactory pit development(GO:0060166)
0.9	2.7	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.9	3.5	GO:1990418	response to sodium phosphate(GO:1904383) response to insulin-like growth factor stimulus(GO:1990418)
0.8	3.9	GO:1904925	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.8	3.1	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.8	3.8	GO:0044856	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.7	2.2	GO:0043465	fermentation(GO:0006113) regulation of fermentation(GO:0043465) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.7	2.9	GO:0042361	menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.7	2.2	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.7	4.2	GO:0045819	positive regulation of glycogen catabolic process(GO:0045819)
0.7	4.1	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.6	2.6	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
0.6	5.0	GO:0002118	aggressive behavior(GO:0002118)
0.6	11.5	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.6	1.8	GO:0000103	sulfate assimilation(GO:0000103)
0.6	4.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.6	2.8	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.6	1.7	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5	2.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.5	1.5	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.5	1.5	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.5	3.3	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.4	1.8	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.4	3.0	GO:0036343	psychomotor behavior(GO:0036343)
0.4	1.7	GO:0015722	canalicular bile acid transport(GO:0015722)
0.4	1.7	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.4	4.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.4	4.5	GO:2000795	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4	11.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.4	1.6	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.4	5.5	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.3	4.4	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.3	3.4	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.3	1.0	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.3	5.6	GO:0008212	mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.3	1.3	GO:0035962	response to interleukin-13(GO:0035962)
0.3	1.2	GO:0021569	rhombomere 3 development(GO:0021569)
0.3	2.9	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.3	4.6	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.3	2.6	GO:0048102	autophagic cell death(GO:0048102)
0.3	0.8	GO:0042631	cellular response to water deprivation(GO:0042631)
0.3	0.8	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
0.3	3.5	GO:0001842	neural fold formation(GO:0001842)
0.2	3.0	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.2	1.5	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.2	1.2	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2	1.5	GO:0001554	luteolysis(GO:0001554)
0.2	2.6	GO:0035585	calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.2	1.7	GO:0045144	meiotic sister chromatid segregation(GO:0045144)
0.2	5.7	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.2	1.6	GO:0044245	polysaccharide digestion(GO:0044245)
0.2	1.6	GO:0015747	hexose phosphate transport(GO:0015712) urate transport(GO:0015747) glucose-6-phosphate transport(GO:0015760)
0.2	19.3	GO:0006958	complement activation, classical pathway(GO:0006958)
0.2	4.8	GO:0007620	copulation(GO:0007620)
0.2	1.2	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2	1.4	GO:0033591	response to L-ascorbic acid(GO:0033591) positive regulation of transmission of nerve impulse(GO:0051971)
0.2	0.8	GO:0002331	pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.2	0.6	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.2	0.9	GO:0034334	adherens junction maintenance(GO:0034334)
0.2	0.6	GO:0002339	B cell selection(GO:0002339)
0.2	2.5	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.2	1.1	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.2	0.8	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.2	1.0	GO:0071321	cellular response to cGMP(GO:0071321)
0.2	2.7	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.2	1.6	GO:0046959	habituation(GO:0046959)
0.2	1.1	GO:0019532	oxalate transport(GO:0019532)
0.2	0.5	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.2	5.1	GO:0030033	microvillus assembly(GO:0030033)
0.1	3.0	GO:0006071	glycerol metabolic process(GO:0006071)
0.1	3.6	GO:0048820	hair follicle maturation(GO:0048820)
0.1	0.5	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
0.1	5.7	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.1	1.5	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1	2.6	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	1.8	GO:0036159	inner dynein arm assembly(GO:0036159)
0.1	2.7	GO:0005513	detection of calcium ion(GO:0005513)
0.1	0.7	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.4	GO:0072233	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1	3.5	GO:0014002	astrocyte development(GO:0014002)
0.1	1.6	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1	2.4	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.1	12.7	GO:0070268	cornification(GO:0070268)
0.1	1.0	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	5.2	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	0.9	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.1	2.0	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.1	4.7	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1	6.7	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.5	GO:0036100	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1	0.6	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.1	0.3	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1	1.4	GO:1990845	adaptive thermogenesis(GO:1990845)
0.1	2.5	GO:0097503	sialylation(GO:0097503)
0.1	0.9	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	1.3	GO:0043691	reverse cholesterol transport(GO:0043691)
0.1	0.8	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.1	1.4	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	2.9	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.1	1.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.1	0.3	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	1.1	GO:0051023	regulation of immunoglobulin secretion(GO:0051023)
0.1	9.2	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1	2.6	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	3.5	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.1	0.9	GO:0035082	axoneme assembly(GO:0035082)
0.1	4.9	GO:0006968	cellular defense response(GO:0006968)
0.1	1.0	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	1.3	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	2.3	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1	1.2	GO:0036315	cellular response to sterol(GO:0036315)
0.1	0.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	1.1	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.1	0.4	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	2.4	GO:0050999	regulation of nitric-oxide synthase activity(GO:0050999)
0.0	5.0	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	6.3	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	4.1	GO:0021510	spinal cord development(GO:0021510)
0.0	0.4	GO:0070475	rRNA base methylation(GO:0070475)
0.0	1.0	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	5.7	GO:0007286	spermatid development(GO:0007286)
0.0	0.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	4.3	GO:0016575	histone deacetylation(GO:0016575)
0.0	1.2	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.6	GO:0032754	positive regulation of interleukin-5 production(GO:0032754)
0.0	2.5	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	3.7	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.9	GO:0097237	cellular response to toxic substance(GO:0097237)
0.0	2.5	GO:0050918	positive chemotaxis(GO:0050918)
0.0	0.2	GO:0030656	regulation of vitamin metabolic process(GO:0030656)
0.0	4.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	12.9	GO:0007283	spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0	0.9	GO:0030449	regulation of complement activation(GO:0030449)
0.0	2.3	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	1.6	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0	0.7	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	2.9	GO:0021987	cerebral cortex development(GO:0021987)
0.0	3.2	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.0	0.7	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.9	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.0	0.4	GO:0015671	oxygen transport(GO:0015671)
0.0	1.2	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.2	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.2	GO:0003334	keratinocyte development(GO:0003334)
0.0	1.2	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	0.1	GO:0089712	L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0	0.7	GO:0016266	O-glycan processing(GO:0016266)
0.0	1.0	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.9	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	1.0	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	1.1	GO:0060041	retina development in camera-type eye(GO:0060041)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	108.9	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
1.5	5.8	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
1.3	6.7	GO:0019814	immunoglobulin complex(GO:0019814)
1.3	4.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.3	11.6	GO:0001520	outer dense fiber(GO:0001520)
1.1	5.3	GO:0032444	activin responsive factor complex(GO:0032444)
1.0	5.2	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.9	12.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.9	11.5	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.8	6.8	GO:0005579	membrane attack complex(GO:0005579)
0.8	2.5	GO:0097224	sperm connecting piece(GO:0097224)
0.8	2.5	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.8	6.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.6	1.7	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.6	1.7	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.5	7.9	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.5	2.9	GO:0032437	cuticular plate(GO:0032437)
0.4	3.6	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4	2.6	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.4	2.8	GO:0030991	intraciliary transport particle A(GO:0030991)
0.4	1.6	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.4	2.7	GO:0044326	dendritic spine neck(GO:0044326)
0.4	7.6	GO:0031089	platelet dense granule lumen(GO:0031089)
0.4	3.4	GO:0097452	GAIT complex(GO:0097452)
0.4	2.6	GO:0042584	chromaffin granule membrane(GO:0042584)
0.3	2.6	GO:0072487	MSL complex(GO:0072487)
0.3	3.0	GO:0046581	intercellular canaliculus(GO:0046581)
0.3	4.7	GO:0044613	nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.3	2.8	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.3	1.4	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.3	3.8	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.3	4.1	GO:0001741	XY body(GO:0001741)
0.3	3.8	GO:0030478	actin cap(GO:0030478)
0.2	5.4	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.2	4.7	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.2	4.5	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	6.7	GO:0031527	filopodium membrane(GO:0031527)
0.2	2.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.2	26.7	GO:0072562	blood microparticle(GO:0072562)
0.2	2.0	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.2	1.0	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2	1.6	GO:0032389	MutLalpha complex(GO:0032389)
0.1	1.8	GO:0005858	axonemal dynein complex(GO:0005858)
0.1	2.6	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	3.9	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.1	1.8	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	3.8	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	1.1	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.1	4.8	GO:0001533	cornified envelope(GO:0001533)
0.1	12.7	GO:0005882	intermediate filament(GO:0005882)
0.1	0.3	GO:0005960	glycine cleavage complex(GO:0005960)
0.1	1.5	GO:0005922	connexon complex(GO:0005922)
0.1	1.0	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	4.2	GO:0005844	polysome(GO:0005844)
0.1	6.9	GO:0035580	specific granule lumen(GO:0035580)
0.1	2.2	GO:0031143	pseudopodium(GO:0031143)
0.1	2.9	GO:0005605	basal lamina(GO:0005605)
0.1	4.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	1.1	GO:0097225	sperm midpiece(GO:0097225)
0.1	1.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.9	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	3.5	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.8	GO:0031045	dense core granule(GO:0031045)
0.0	1.8	GO:0005859	muscle myosin complex(GO:0005859)
0.0	6.9	GO:0055037	recycling endosome(GO:0055037)
0.0	3.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	5.4	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	3.5	GO:0005604	basement membrane(GO:0005604)
0.0	0.5	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	1.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	1.6	GO:0031526	brush border membrane(GO:0031526)
0.0	2.6	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	4.3	GO:0032587	ruffle membrane(GO:0032587)
0.0	1.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	2.0	GO:0001726	ruffle(GO:0001726)
0.0	4.6	GO:0030139	endocytic vesicle(GO:0030139)
0.0	23.6	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.6	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.5	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	1.3	GO:0043195	terminal bouton(GO:0043195)
0.0	0.9	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	1.1	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.4	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	1.5	GO:0030018	Z disc(GO:0030018)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	11.1	GO:0061769	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.9	7.5	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
1.8	108.9	GO:0034987	immunoglobulin receptor binding(GO:0034987)
1.4	4.3	GO:0015489	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
1.3	3.8	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.0	3.0	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
1.0	3.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
1.0	3.8	GO:0097001	ceramide binding(GO:0097001)
0.9	3.6	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.8	2.5	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.8	5.0	GO:0004882	androgen receptor activity(GO:0004882)
0.8	4.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.7	3.5	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.7	4.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.7	4.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.6	14.8	GO:0051787	misfolded protein binding(GO:0051787)
0.6	7.4	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.6	3.5	GO:0005497	androgen binding(GO:0005497)
0.5	1.5	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.5	16.8	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.4	1.8	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.4	4.8	GO:0030280	structural constituent of epidermis(GO:0030280)
0.4	1.6	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.4	3.1	GO:0015232	heme transporter activity(GO:0015232)
0.4	5.7	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.4	1.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.4	1.1	GO:0005174	CD40 receptor binding(GO:0005174)
0.4	1.4	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.3	2.6	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.3	1.3	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.3	3.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.3	1.2	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3	0.9	GO:0097259	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.3	2.6	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.3	2.6	GO:0016015	morphogen activity(GO:0016015)
0.3	0.8	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.3	2.8	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.3	3.8	GO:0045159	myosin II binding(GO:0045159)
0.3	2.5	GO:0032027	myosin light chain binding(GO:0032027)
0.2	0.7	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.2	2.7	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.2	5.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.2	2.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2	7.6	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.2	1.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.2	1.7	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.2	1.5	GO:0008172	S-methyltransferase activity(GO:0008172)
0.2	2.6	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2	1.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.2	4.3	GO:0070330	aromatase activity(GO:0070330)
0.2	1.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2	5.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.2	0.5	GO:0005042	netrin receptor activity(GO:0005042)
0.2	1.1	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2	5.3	GO:0070410	co-SMAD binding(GO:0070410)
0.2	19.6	GO:0005518	collagen binding(GO:0005518)
0.2	1.2	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.2	3.9	GO:0019789	SUMO transferase activity(GO:0019789)
0.2	5.4	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.2	4.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	1.6	GO:0032138	single base insertion or deletion binding(GO:0032138)
0.2	2.0	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.2	5.4	GO:0042056	chemoattractant activity(GO:0042056)
0.2	2.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2	3.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.7	GO:0004905	type I interferon receptor activity(GO:0004905)
0.1	1.6	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1	37.2	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	0.8	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.8	GO:0001849	complement component C1q binding(GO:0001849)
0.1	1.5	GO:0051434	BH3 domain binding(GO:0051434)
0.1	1.5	GO:0032393	MHC class I receptor activity(GO:0032393)
0.1	0.6	GO:0051400	BH domain binding(GO:0051400)
0.1	1.6	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	3.3	GO:0030506	ankyrin binding(GO:0030506)
0.1	2.4	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.1	2.8	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	1.8	GO:0045503	dynein light chain binding(GO:0045503)
0.1	2.7	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.3	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	2.7	GO:0001671	ATPase activator activity(GO:0001671)
0.1	1.9	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	1.1	GO:0030957	Tat protein binding(GO:0030957)
0.1	3.0	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	6.1	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	4.3	GO:0004407	histone deacetylase activity(GO:0004407)
0.1	2.5	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	1.8	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	1.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	2.1	GO:0001972	retinoic acid binding(GO:0001972)
0.1	6.8	GO:0001618	virus receptor activity(GO:0001618)
0.1	4.6	GO:0019843	rRNA binding(GO:0019843)
0.1	3.0	GO:0004177	aminopeptidase activity(GO:0004177)
0.1	1.0	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.5	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	1.7	GO:0071837	HMG box domain binding(GO:0071837)
0.0	1.2	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.9	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.2	GO:0015235	cobalamin transporter activity(GO:0015235)
0.0	0.8	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	1.0	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.3	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	1.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	7.8	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	7.6	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.9	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	2.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.4	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.5	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.3	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	12.8	GO:0005198	structural molecule activity(GO:0005198)
0.0	0.6	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	2.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	3.0	GO:0019902	phosphatase binding(GO:0019902)
0.0	1.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.8	GO:0017022	myosin binding(GO:0017022)
0.0	0.4	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	1.0	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	1.4	GO:0005178	integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	12.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.3	4.8	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.2	12.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.2	6.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.2	5.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	21.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.2	4.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.2	2.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	6.5	PID RAS PATHWAY	Regulation of Ras family activation
0.1	3.8	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	3.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	6.7	PID BCR 5PATHWAY	BCR signaling pathway
0.1	11.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	2.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	3.5	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	5.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	3.5	PID ALK1 PATHWAY	ALK1 signaling events
0.1	5.7	PID PLK1 PATHWAY	PLK1 signaling events
0.1	2.3	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	2.8	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	5.0	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.1	6.9	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	0.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	5.0	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	1.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	2.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	2.0	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.8	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	1.5	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	2.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	3.4	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.4	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	1.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	4.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	3.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	2.7	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.5	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	16.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.4	12.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	7.5	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.3	6.8	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.3	3.6	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.2	2.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.2	2.5	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2	5.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	2.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	7.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	6.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.8	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.7	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	4.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	3.7	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	4.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	5.2	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.1	1.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	3.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	3.9	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	1.7	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	1.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	2.6	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.1	11.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	3.0	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.5	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	2.2	REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	Genes involved in Signaling by the B Cell Receptor (BCR)
0.1	2.9	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	1.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	6.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	5.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	1.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	4.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	2.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.6	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	4.3	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1	1.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	2.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.7	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	2.1	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	3.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	8.5	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	2.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.4	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis

Results for NR6A1

Z-value: 0.98

Motif logo

Transcription factors associated with NR6A1

Activity-expression correlation:

Activity profile of NR6A1 motif

Sorted Z-values of NR6A1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: