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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ONECUT1

Z-value: 0.76

Motif logo

Transcription factors associated with ONECUT1

Gene Symbol Gene ID Gene Info
ENSG00000169856.9 ONECUT1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ONECUT1hg38_v1_chr15_-_52790324_527903520.412.2e-10Click!

Activity profile of ONECUT1 motif

Sorted Z-values of ONECUT1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_57597563 16.52 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr12_-_9115907 15.68 ENST00000318602.12
alpha-2-macroglobulin
chr17_-_28370283 15.27 ENST00000226218.9
vitronectin
chr10_-_51699559 12.81 ENST00000331173.6
cleavage stimulation factor subunit 2 tau variant
chr9_-_114078293 12.69 ENST00000265132.8
alpha-1-microglobulin/bikunin precursor
chr13_-_46105009 11.06 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
carboxypeptidase B2
chr3_+_52777580 10.65 ENST00000273283.7
inter-alpha-trypsin inhibitor heavy chain 1
chr3_+_186666003 7.98 ENST00000232003.5
histidine rich glycoprotein
chr8_-_27611325 7.86 ENST00000523500.5
clusterin
chr2_+_234050732 7.49 ENST00000425558.1
secreted phosphoprotein 2
chr19_+_44946043 7.41 ENST00000252490.7
ENST00000591597.5
apolipoprotein C2
chr2_+_234050679 7.26 ENST00000373368.5
ENST00000168148.8
secreted phosphoprotein 2
chr12_+_56752449 7.00 ENST00000554643.5
ENST00000556650.5
ENST00000554150.5
ENST00000554155.1
hydroxysteroid 17-beta dehydrogenase 6
chr19_+_37507129 6.94 ENST00000586138.5
ENST00000588578.5
ENST00000587986.5
zinc finger protein 793
chr16_+_27203480 6.87 ENST00000286096.9
lysine demethylase 8
chr17_-_66229380 6.68 ENST00000205948.11
apolipoprotein H
chr1_+_159587817 6.64 ENST00000255040.3
amyloid P component, serum
chr1_+_25272492 6.30 ENST00000454452.6
Rh blood group D antigen
chr12_+_69348372 5.62 ENST00000261267.7
ENST00000549690.1
ENST00000548839.1
lysozyme
chr19_+_44946009 5.37 ENST00000592257.5
apolipoprotein C2
chr1_+_25272439 5.35 ENST00000648012.1
Rh blood group D antigen
chr17_+_42900791 5.25 ENST00000592383.5
ENST00000253801.7
ENST00000585489.1
glucose-6-phosphatase catalytic subunit 1
chr1_-_25420792 5.20 ENST00000346452.8
ENST00000340849.8
ENST00000349438.8
ENST00000413854.5
ENST00000294413.13
Rh blood group CcEe antigens
chr12_-_11269696 5.15 ENST00000381842.7
proline rich protein BstNI subfamily 3
chr12_-_11269805 4.95 ENST00000538488.2
proline rich protein BstNI subfamily 3
chr18_+_74597850 4.87 ENST00000582337.5
ENST00000299687.10
zinc finger protein 407
chr4_-_74099187 4.85 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr1_+_56854764 4.66 ENST00000361249.4
complement C8 alpha chain
chr1_+_77779618 4.49 ENST00000370791.7
ENST00000443751.3
ENST00000645756.1
ENST00000643390.1
ENST00000642959.1
mitoguardin 1
chr9_-_135961310 4.22 ENST00000371756.4
UBA domain containing 1
chr12_+_21526287 4.04 ENST00000256969.7
spexin hormone
chr10_+_96304392 4.03 ENST00000630152.1
DNA nucleotidylexotransferase
chr3_+_101827982 3.79 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr8_+_119873710 3.78 ENST00000523492.5
ENST00000286234.6
DEP domain containing MTOR interacting protein
chr10_+_113553039 3.76 ENST00000351270.4
hyaluronan binding protein 2
chr10_+_49637400 3.75 ENST00000640822.1
choline O-acetyltransferase
chrX_+_71215156 3.54 ENST00000374029.2
ENST00000675209.1
ENST00000647424.1
ENST00000675368.1
ENST00000675609.1
ENST00000646835.1
ENST00000447581.2
gap junction protein beta 1
chr10_+_96304425 3.44 ENST00000371174.5
DNA nucleotidylexotransferase
chr3_-_171026709 3.35 ENST00000314251.8
solute carrier family 2 member 2
chr1_-_52404387 3.33 ENST00000371566.1
ENST00000371568.8
origin recognition complex subunit 1
chr1_+_25272527 3.17 ENST00000342055.9
ENST00000357542.8
ENST00000417538.6
ENST00000423810.6
ENST00000568195.5
Rh blood group D antigen
chr14_-_26597430 3.15 ENST00000344429.9
ENST00000574031.1
ENST00000465357.6
ENST00000547619.5
NOVA alternative splicing regulator 1
chr1_-_202710428 3.13 ENST00000367268.5
synaptotagmin 2
chr11_-_19201976 3.05 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
cysteine and glycine rich protein 3
chr14_-_26598025 3.04 ENST00000539517.7
NOVA alternative splicing regulator 1
chrX_-_132489954 3.02 ENST00000370844.5
muscleblind like splicing regulator 3
chr15_-_85794902 3.00 ENST00000337975.6
kelch like family member 25
chr1_+_25272502 2.99 ENST00000328664.9
Rh blood group D antigen
chr11_-_72674394 2.90 ENST00000418754.6
ENST00000334456.10
ENST00000542969.2
phosphodiesterase 2A
chr19_-_48740573 2.87 ENST00000222145.9
Ras interacting protein 1
chr10_-_92243246 2.80 ENST00000412050.8
ENST00000614585.4
cytoplasmic polyadenylation element binding protein 3
chr9_-_75088140 2.77 ENST00000361092.9
ENST00000376811.5
nicotinamide riboside kinase 1
chr13_+_29428709 2.77 ENST00000542829.1
microtubule associated scaffold protein 2
chr9_-_75088198 2.73 ENST00000376808.8
nicotinamide riboside kinase 1
chr7_-_152676130 2.71 ENST00000359321.2
X-ray repair cross complementing 2
chr17_-_4704040 2.70 ENST00000570571.5
ENST00000575101.1
ENST00000574876.5
ENST00000572293.7
proline, glutamate and leucine rich protein 1
chr1_+_25272479 2.66 ENST00000622561.4
Rh blood group D antigen
chr2_+_233691607 2.60 ENST00000373424.5
ENST00000441351.1
UDP glucuronosyltransferase family 1 member A6
chr7_+_101815983 2.54 ENST00000292538.9
ENST00000622516.6
ENST00000393824.7
ENST00000547394.6
ENST00000360264.7
ENST00000425244.6
cut like homeobox 1
chr7_+_55019032 2.53 ENST00000342916.7
ENST00000454757.6
ENST00000420316.6
epidermal growth factor receptor
chr17_-_17591658 2.52 ENST00000435340.6
ENST00000255389.10
ENST00000395781.6
phosphatidylethanolamine N-methyltransferase
chr11_-_30016945 2.47 ENST00000328224.7
potassium voltage-gated channel subfamily A member 4
chr12_+_111034136 2.46 ENST00000261726.11
cut like homeobox 2
chr4_+_158210479 2.43 ENST00000504569.5
ENST00000509278.5
ENST00000514558.5
ENST00000503200.5
ENST00000296529.11
transmembrane protein 144
chr15_-_99249523 2.40 ENST00000560235.1
ENST00000394132.7
ENST00000560860.5
ENST00000558078.5
ENST00000560772.5
tetratricopeptide repeat domain 23
chr17_-_17582417 2.40 ENST00000395783.5
phosphatidylethanolamine N-methyltransferase
chr19_+_37506931 2.36 ENST00000627814.3
ENST00000587143.5
zinc finger protein 793
chr5_-_177409535 2.34 ENST00000253496.4
coagulation factor XII
chr6_+_72366730 2.32 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr1_+_207089195 2.28 ENST00000452902.6
complement component 4 binding protein beta
chr11_+_119067774 2.27 ENST00000621676.5
ENST00000614944.4
VPS11 core subunit of CORVET and HOPS complexes
chr4_-_74038681 2.26 ENST00000296026.4
C-X-C motif chemokine ligand 3
chr7_-_122144231 2.24 ENST00000679511.1
ENST00000417368.7
ENST00000473553.5
aminoadipate-semialdehyde synthase
chr1_+_196888014 2.19 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr21_+_25734948 2.14 ENST00000400075.4
GA binding protein transcription factor subunit alpha
chr18_-_27990256 2.13 ENST00000675173.1
cadherin 2
chr5_-_116574802 2.12 ENST00000343348.11
semaphorin 6A
chr22_+_50738198 2.12 ENST00000216139.10
ENST00000529621.1
acrosin
chr15_+_45129933 2.11 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
dual oxidase 1
chr2_+_44941695 2.08 ENST00000260653.5
SIX homeobox 3
chr12_+_8843236 2.07 ENST00000541459.5
alpha-2-macroglobulin like 1
chr19_-_23687163 2.05 ENST00000601010.5
ENST00000601935.5
ENST00000600313.5
ENST00000596211.5
ENST00000359788.9
ENST00000599168.1
zinc finger protein 675
chr20_+_54475647 2.01 ENST00000395939.5
docking protein 5
chr7_+_99828010 2.01 ENST00000631161.2
ENST00000354829.7
ENST00000342499.8
ENST00000417625.5
ENST00000415413.5
ENST00000444905.5
ENST00000222382.5
ENST00000312017.9
cytochrome P450 family 3 subfamily A member 43
chr11_+_61228377 2.00 ENST00000537932.5
pepsinogen A4
chr10_-_49269 2.00 ENST00000562809.1
ENST00000568866.5
ENST00000561967.1
ENST00000568584.6
tubulin beta 8 class VIII
chr20_+_54475584 1.98 ENST00000262593.10
docking protein 5
chr7_-_42152396 1.96 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI family zinc finger 3
chr1_-_158554405 1.96 ENST00000641282.1
ENST00000641622.1
olfactory receptor family 6 subfamily Y member 1
chr17_+_41712325 1.94 ENST00000329402.4
gastrin
chr7_-_42152444 1.93 ENST00000479210.1
GLI family zinc finger 3
chr22_-_37109409 1.92 ENST00000406725.6
transmembrane serine protease 6
chr3_-_161105224 1.91 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr7_+_55019010 1.90 ENST00000344576.7
ENST00000275493.7
ENST00000455089.5
epidermal growth factor receptor
chr11_-_19202004 1.90 ENST00000648719.1
cysteine and glycine rich protein 3
chr1_-_151831768 1.89 ENST00000318247.7
RAR related orphan receptor C
chr19_+_46297032 1.88 ENST00000377670.9
hypoxia inducible factor 3 subunit alpha
chr11_+_131370478 1.78 ENST00000374791.7
ENST00000683400.1
ENST00000436745.5
neurotrimin
chr5_+_141421064 1.77 ENST00000518882.2
protocadherin gamma subfamily A, 11
chr5_+_141421020 1.76 ENST00000622044.1
ENST00000398587.7
protocadherin gamma subfamily A, 11
chr1_+_212565334 1.75 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr2_+_70900546 1.72 ENST00000234392.3
ventral anterior homeobox 2
chr1_+_207089283 1.69 ENST00000391923.1
complement component 4 binding protein beta
chr3_-_99850976 1.69 ENST00000487087.5
filamin A interacting protein 1 like
chr2_+_90038848 1.66 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr19_+_45093140 1.65 ENST00000544069.2
ENST00000221462.9
protein phosphatase 1 regulatory subunit 37
chr3_+_120908072 1.60 ENST00000273666.10
ENST00000471454.6
ENST00000472879.5
ENST00000497029.5
ENST00000492541.5
syntaxin binding protein 5 like
chr1_+_207089233 1.57 ENST00000243611.9
ENST00000367076.7
complement component 4 binding protein beta
chr9_+_127803208 1.56 ENST00000373225.7
ENST00000431857.5
folylpolyglutamate synthase
chr16_-_3372666 1.55 ENST00000399974.5
MT-RNR2 like 4
chr14_-_35404650 1.54 ENST00000553342.1
ENST00000557140.5
ENST00000216797.10
NFKB inhibitor alpha
chr12_+_70366277 1.44 ENST00000258111.5
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr2_-_217842154 1.44 ENST00000446688.5
tensin 1
chr1_+_156619406 1.44 ENST00000255039.6
ENST00000456112.1
hyaluronan and proteoglycan link protein 2
chr1_+_152878312 1.40 ENST00000368765.4
sperm mitochondria associated cysteine rich protein
chr8_-_24956604 1.39 ENST00000610854.2
neurofilament light
chr2_+_89947508 1.36 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr3_+_119782094 1.35 ENST00000393716.8
nuclear receptor subfamily 1 group I member 2
chr3_+_181711915 1.31 ENST00000325404.3
SRY-box transcription factor 2
chr20_-_22585451 1.31 ENST00000377115.4
forkhead box A2
chr19_+_5681000 1.31 ENST00000581893.5
ENST00000411793.6
ENST00000301382.8
ENST00000581773.5
ENST00000339423.7
ENST00000423665.6
ENST00000583928.5
ENST00000342970.6
ENST00000422535.6
ENST00000581521.5
hydroxysteroid 11-beta dehydrogenase 1 like
chr12_+_101594849 1.28 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr22_-_37109703 1.28 ENST00000406856.7
ENST00000676104.1
transmembrane serine protease 6
chrX_-_72572794 1.28 ENST00000421523.6
ENST00000648036.1
ENST00000373559.8
ENST00000648139.1
ENST00000650636.1
ENST00000648962.1
ENST00000373560.7
ENST00000373568.7
ENST00000373573.9
ENST00000647654.1
ENST00000647859.1
ENST00000415409.6
ENST00000648298.1
ENST00000649752.1
ENST00000373571.6
ENST00000647980.1
ENST00000650126.1
ENST00000373554.6
ENST00000648870.1
ENST00000373556.8
ENST00000647886.1
ENST00000648452.1
ENST00000647594.1
ENST00000373583.6
ENST00000648922.1
histone deacetylase 8
novel protein
chr21_-_42396043 1.25 ENST00000433957.7
ENST00000644384.2
ENST00000652415.1
ENST00000398397.3
transmembrane serine protease 3
chr7_-_116030735 1.24 ENST00000393485.5
transcription factor EC
chr3_+_108589667 1.19 ENST00000361582.8
ENST00000486815.5
DAZ interacting zinc finger protein 3
chr1_-_110607970 1.18 ENST00000638532.1
potassium voltage-gated channel subfamily A member 2
chrX_+_10156960 1.18 ENST00000380833.9
chloride voltage-gated channel 4
chr7_+_95772506 1.18 ENST00000537881.5
ENST00000447467.6
ENST00000524053.5
ENST00000324972.10
ENST00000630942.2
ENST00000437599.5
ENST00000359388.8
ENST00000413338.5
dynein cytoplasmic 1 intermediate chain 1
chr3_+_11137093 1.17 ENST00000438284.2
histamine receptor H1
chr15_-_64046322 1.17 ENST00000457488.5
ENST00000612884.4
death associated protein kinase 2
chr4_+_125314918 1.12 ENST00000674496.2
ENST00000394329.9
FAT atypical cadherin 4
chr18_-_49557 1.07 ENST00000308911.8
tubulin beta 8B
chrX_+_123184260 1.06 ENST00000620443.2
ENST00000622768.5
ENST00000611689.4
glutamate ionotropic receptor AMPA type subunit 3
chr18_+_52340179 1.05 ENST00000442544.7
DCC netrin 1 receptor
chr7_+_129368123 1.04 ENST00000460109.5
ENST00000474594.5
adenosylhomocysteinase like 2
chr20_+_59940362 1.02 ENST00000360816.8
family with sequence similarity 217 member B
chr17_-_27893339 1.02 ENST00000460380.6
ENST00000379102.8
ENST00000508862.5
ENST00000582441.1
LYR motif containing 9
novel protein
chr7_+_98106852 1.02 ENST00000297293.6
lemur tyrosine kinase 2
chr10_-_60572599 1.01 ENST00000503366.5
ankyrin 3
chr11_-_35418966 0.97 ENST00000531628.2
solute carrier family 1 member 2
chr12_-_21334858 0.92 ENST00000445053.1
ENST00000458504.5
ENST00000422327.5
ENST00000683939.1
solute carrier organic anion transporter family member 1A2
chr5_+_140786136 0.87 ENST00000378133.4
ENST00000504120.4
protocadherin alpha 1
chr22_-_31750120 0.83 ENST00000327423.11
ENST00000412743.1
proline rich 14 like
chr13_+_29428603 0.82 ENST00000380808.6
microtubule associated scaffold protein 2
chr4_-_174522315 0.80 ENST00000514584.5
15-hydroxyprostaglandin dehydrogenase
chr19_-_58573555 0.80 ENST00000599369.5
myeloid zinc finger 1
chrX_+_110520312 0.79 ENST00000602699.1
teratocarcinoma-derived growth factor 1 pseudogene 3
chr7_-_116030750 0.79 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr7_+_143288215 0.79 ENST00000619992.4
ENST00000310447.10
caspase 2
chr6_+_27957241 0.77 ENST00000244623.1
olfactory receptor family 2 subfamily B member 6
chr20_+_44355692 0.76 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr14_+_23953729 0.73 ENST00000558263.5
ENST00000543741.6
ENST00000313250.10
ENST00000397075.7
ENST00000397074.7
ENST00000559632.5
ENST00000558581.5
dehydrogenase/reductase 4
chr13_-_36346319 0.72 ENST00000438666.7
spartin
chr4_+_77157189 0.72 ENST00000316355.10
ENST00000502280.5
cyclin G2
chr1_+_21570303 0.69 ENST00000374830.2
alkaline phosphatase, biomineralization associated
chr1_+_17249088 0.69 ENST00000375460.3
peptidyl arginine deiminase 3
chr20_+_21705651 0.68 ENST00000398485.6
ENST00000613128.5
paired box 1
chr1_+_52404591 0.66 ENST00000257181.10
pre-mRNA processing factor 38A
chr2_-_172102893 0.61 ENST00000234198.9
ENST00000466293.2
distal-less homeobox 2
chr4_+_109912877 0.61 ENST00000265171.10
ENST00000509793.5
ENST00000652245.1
epidermal growth factor
chr8_+_32646838 0.61 ENST00000651333.1
ENST00000652592.1
neuregulin 1
chr10_-_125816596 0.61 ENST00000368786.5
uroporphyrinogen III synthase
chr14_-_106211453 0.60 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr5_-_20575850 0.60 ENST00000507958.5
cadherin 18
chr19_+_2785481 0.55 ENST00000307741.11
ENST00000585338.1
thimet oligopeptidase 1
chr17_+_81395449 0.55 ENST00000675386.2
BAH domain and coiled-coil containing 1
chr5_-_22853320 0.53 ENST00000504376.6
ENST00000382254.6
cadherin 12
chr8_-_23854796 0.53 ENST00000290271.7
stanniocalcin 1
chr13_-_52011337 0.52 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATPase copper transporting beta
chr9_-_98708856 0.49 ENST00000259455.4
gamma-aminobutyric acid type B receptor subunit 2
chr1_-_94121105 0.48 ENST00000649773.1
ENST00000370225.4
ATP binding cassette subfamily A member 4
chr8_+_127409026 0.48 ENST00000465342.4
POU class 5 homeobox 1B
chr12_-_109996216 0.48 ENST00000551209.5
ENST00000550186.5
GIT ArfGAP 2
chr22_+_23856703 0.48 ENST00000345044.10
solute carrier family 2 member 11
chr14_+_22543179 0.47 ENST00000390534.1
T cell receptor alpha joining 3
chr6_+_32439866 0.45 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr12_-_109996291 0.45 ENST00000320063.10
ENST00000457474.6
ENST00000547815.5
ENST00000361006.9
ENST00000355312.8
ENST00000354574.8
ENST00000553118.5
GIT ArfGAP 2
chr2_-_85561513 0.43 ENST00000430215.7
gamma-glutamyl carboxylase
chr10_-_48524236 0.39 ENST00000374170.5
Rho GTPase activating protein 22
chr17_+_81395469 0.39 ENST00000584436.7
BAH domain and coiled-coil containing 1
chr13_-_113364141 0.38 ENST00000620217.4
ENST00000375430.8
growth hormone regulated TBC protein 1
chr12_+_15322529 0.37 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chr16_-_20691256 0.34 ENST00000307493.8
acyl-CoA synthetase medium chain family member 1
chr2_+_33436304 0.33 ENST00000402538.7
RAS guanyl releasing protein 3
chr6_-_132734692 0.32 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr20_+_23491090 0.32 ENST00000449810.5
ENST00000246012.2
cystatin 8
chr19_-_45370384 0.28 ENST00000485403.6
ENST00000586856.1
ENST00000586131.6
ENST00000391945.10
ENST00000684407.1
ENST00000391944.8
ERCC excision repair 2, TFIIH core complex helicase subunit
chr7_+_101815904 0.28 ENST00000437600.9
ENST00000645010.1
ENST00000646649.1
cut like homeobox 1
chr4_-_110641920 0.25 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
paired like homeodomain 2
chr1_-_115841116 0.23 ENST00000320238.3
nescient helix-loop-helix 2
chr19_-_4535221 0.23 ENST00000381848.7
ENST00000586133.1
perilipin 5
chr12_+_15322480 0.22 ENST00000674188.1
ENST00000281171.9
ENST00000543886.6
protein tyrosine phosphatase receptor type O
chr6_-_138218491 0.20 ENST00000527246.3
prostate and breast cancer overexpressed 1
chr8_-_107498041 0.19 ENST00000297450.7
angiopoietin 1
chr6_-_161274042 0.19 ENST00000320285.9
1-acylglycerol-3-phosphate O-acyltransferase 4
chr6_-_161274010 0.17 ENST00000366911.9
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chr4_-_82562240 0.14 ENST00000515780.6
transmembrane protein 150C
chrX_-_109482075 0.11 ENST00000218006.3
guanylate cyclase 2F, retinal

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 32.2 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.8 11.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.6 12.8 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
2.2 6.6 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
2.0 8.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
1.7 15.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.6 7.9 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.4 1.4 GO:0046618 drug export(GO:0046618)
1.3 3.9 GO:0022018 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
1.2 7.0 GO:0006710 androgen catabolic process(GO:0006710)
1.2 12.8 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
1.1 5.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.1 3.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
1.1 6.7 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
1.1 4.4 GO:0033594 response to hydroxyisoflavone(GO:0033594)
1.0 5.0 GO:0035995 detection of muscle stretch(GO:0035995)
1.0 12.7 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.9 2.8 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.9 2.7 GO:1902866 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.8 2.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.8 25.7 GO:0015695 organic cation transport(GO:0015695)
0.7 2.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.7 2.9 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.7 5.5 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.7 4.0 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.6 4.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.6 3.5 GO:0007341 penetration of zona pellucida(GO:0007341)
0.6 1.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5 6.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.5 1.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.5 1.4 GO:1903937 response to acrylamide(GO:1903937)
0.5 2.7 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.4 1.3 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 1.3 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 2.0 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.4 1.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4 3.5 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.3 2.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.3 4.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.3 1.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 1.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.3 2.6 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 4.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 2.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 1.0 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 8.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.2 2.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 0.7 GO:0071529 cementum mineralization(GO:0071529)
0.2 2.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.7 GO:0061056 sclerotome development(GO:0061056)
0.2 1.5 GO:0070417 cellular response to cold(GO:0070417) nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2 0.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 3.2 GO:0097264 self proteolysis(GO:0097264)
0.2 10.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 10.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 2.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.2 0.5 GO:0060003 copper ion export(GO:0060003)
0.2 0.7 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 7.5 GO:0033198 response to ATP(GO:0033198)
0.2 1.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.2 14.7 GO:0046849 bone remodeling(GO:0046849)
0.2 0.6 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.4 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 1.2 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 5.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 4.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.8 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 1.2 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.2 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 1.2 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.1 1.7 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.1 2.5 GO:0007614 short-term memory(GO:0007614)
0.1 2.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 3.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.9 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.1 2.8 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 3.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.2 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1 3.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 2.9 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 1.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.8 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.8 GO:0097070 ductus arteriosus closure(GO:0097070)
0.1 1.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.9 GO:0032094 response to food(GO:0032094)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 2.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 1.0 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 1.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 3.9 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.4 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 2.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 4.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.4 GO:0010761 fibroblast migration(GO:0010761)
0.0 1.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.0 GO:0033572 transferrin transport(GO:0033572)
0.0 1.2 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.7 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 1.6 GO:0001570 vasculogenesis(GO:0001570)
0.0 3.7 GO:0007626 locomotory behavior(GO:0007626)
0.0 1.9 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.8 12.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.1 4.4 GO:0070435 Shc-EGFR complex(GO:0070435)
1.1 21.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.9 12.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.7 7.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.7 2.1 GO:0043159 acrosomal matrix(GO:0043159)
0.6 4.7 GO:0005579 membrane attack complex(GO:0005579)
0.6 1.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.5 2.7 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.4 40.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 1.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 3.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 3.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.2 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 4.0 GO:0031045 dense core granule(GO:0031045)
0.2 2.0 GO:0072687 meiotic spindle(GO:0072687)
0.2 3.5 GO:0005922 connexon complex(GO:0005922)
0.2 2.3 GO:0030897 HOPS complex(GO:0030897)
0.2 2.0 GO:0097486 multivesicular body lumen(GO:0097486)
0.2 2.8 GO:0097440 apical dendrite(GO:0097440)
0.2 2.1 GO:0005916 fascia adherens(GO:0005916)
0.2 7.5 GO:0000791 euchromatin(GO:0000791)
0.1 0.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 1.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 0.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 2.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 3.9 GO:0016592 mediator complex(GO:0016592)
0.1 1.2 GO:0033010 paranodal junction(GO:0033010)
0.1 15.0 GO:0072562 blood microparticle(GO:0072562)
0.1 5.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.1 4.9 GO:0031526 brush border membrane(GO:0031526)
0.1 5.5 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 3.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0032982 myosin filament(GO:0032982)
0.0 5.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.0 GO:0043194 axon initial segment(GO:0043194)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 5.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 4.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.7 GO:0098793 presynapse(GO:0098793)
0.0 2.2 GO:0055037 recycling endosome(GO:0055037)
0.0 2.8 GO:0030018 Z disc(GO:0030018)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.1 GO:0005795 Golgi stack(GO:0005795)
0.0 1.2 GO:0005776 autophagosome(GO:0005776)
0.0 25.0 GO:0005615 extracellular space(GO:0005615)
0.0 29.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.7 GO:0019959 interleukin-8 binding(GO:0019959)
4.9 19.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.5 12.7 GO:0019862 IgA binding(GO:0019862)
1.6 4.9 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.4 5.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.1 3.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
1.1 4.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.0 15.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.9 3.7 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.9 5.6 GO:0003796 lysozyme activity(GO:0003796)
0.8 5.0 GO:0001849 complement component C1q binding(GO:0001849)
0.7 25.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.7 2.1 GO:0042806 amidase activity(GO:0004040) fucose binding(GO:0042806)
0.6 7.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.5 6.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 7.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.5 5.0 GO:0031433 telethonin binding(GO:0031433)
0.4 10.2 GO:0051787 misfolded protein binding(GO:0051787)
0.4 1.9 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.4 11.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 37.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 1.1 GO:0005042 netrin receptor activity(GO:0005042)
0.3 3.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.3 1.9 GO:0008142 oxysterol binding(GO:0008142)
0.3 2.9 GO:0030911 TPR domain binding(GO:0030911)
0.2 7.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 0.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 3.5 GO:0005243 gap junction channel activity(GO:0005243)
0.2 0.8 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 4.7 GO:0001848 complement binding(GO:0001848)
0.2 2.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 0.5 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.2 0.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 1.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 2.7 GO:0000150 recombinase activity(GO:0000150)
0.2 0.5 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2 0.6 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 2.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.2 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 2.5 GO:0030955 potassium ion binding(GO:0030955)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 13.5 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 2.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 4.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.0 GO:0070330 aromatase activity(GO:0070330)
0.1 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.4 GO:0043274 phospholipase binding(GO:0043274)
0.1 4.0 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.3 GO:0031432 titin binding(GO:0031432)
0.1 2.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.6 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 2.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 3.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 2.9 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 0.2 GO:0035473 lipase binding(GO:0035473)
0.1 1.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.3 GO:0035198 miRNA binding(GO:0035198)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 12.6 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 9.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 3.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 2.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 3.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.2 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 2.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 15.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 7.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 70.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 4.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 4.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 5.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 5.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 34.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.6 12.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 8.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 12.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 3.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 5.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 3.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 3.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 4.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 3.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 3.1 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 2.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 15.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 14.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 7.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 4.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 3.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 0.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 2.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE