ISMARA results: ONECUT2

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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ONECUT2_ONECUT3

Z-value: 0.64

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Transcription factors associated with ONECUT2_ONECUT3

Gene Symbol	Gene ID	Gene Info
ONECUT2 Ensembl NCBI GeneCards UniProt	ENSG00000119547.6	ONECUT2
ONECUT3 Ensembl NCBI GeneCards UniProt	ENSG00000205922.5	ONECUT3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ONECUT2	hg38_v1_chr18_+_57435366_57435391	-0.13	6.5e-02	Click!
ONECUT3	hg38_v1_chr19_+_1753499_1753521	-0.01	8.4e-01	Click!

Activity profile of ONECUT2_ONECUT3 motif

Sorted Z-values of ONECUT2_ONECUT3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT2_ONECUT3

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr13_-_35855627 Show fit	10.09	ENST00000379893.5	DCLK1 Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr3_+_159839847 Show fit	7.15	ENST00000445224.6	SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	schwannomin interacting protein 1
chr16_+_56191476 Show fit	6.49	ENST00000262493.12	GNAO1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha o1
chr10_+_93757831 Show fit	6.35	ENST00000629035.2	LGI1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich glioma inactivated 1
chr10_+_93757857 Show fit	5.77	ENST00000478763.2 ENST00000371418.9 ENST00000630184.2 ENST00000630047.2 ENST00000637689.1	LGI1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich glioma inactivated 1
chr13_-_35855758 Show fit	5.74	ENST00000615680.4	DCLK1 Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr1_-_31919368 Show fit	5.40	ENST00000457805.6 ENST00000602725.5 ENST00000679970.1	PTP4A2 Ensembl NCBI GeneCards UniProt Show fit ENSG00000288678.1 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A2 novel protein
chr3_-_142028597 Show fit	4.82	ENST00000467667.5	TFDP2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2
chr20_+_37777262 Show fit	4.53	ENST00000373469.1	CTNNBL1 Ensembl NCBI GeneCards UniProt Show fit	catenin beta like 1
chr4_+_157220654 Show fit	4.44	ENST00000393815.6	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr1_-_31919093 Show fit	4.29	ENST00000602683.5 ENST00000470404.5	PTP4A2 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A2
chr4_+_157220691 Show fit	3.95	ENST00000509417.5 ENST00000645636.1 ENST00000296526.12 ENST00000264426.14	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr7_-_105269007 Show fit	3.93	ENST00000357311.7	SRPK2 Ensembl NCBI GeneCards UniProt Show fit	SRSF protein kinase 2
chr4_-_101347471 Show fit	3.67	ENST00000323055.10 ENST00000512215.5	PPP3CA Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr11_-_107858777 Show fit	3.66	ENST00000525815.6	SLC35F2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 member F2
chr3_-_197226351 Show fit	3.66	ENST00000656428.1	DLG1 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 1
chr4_-_101347492 Show fit	3.59	ENST00000394854.8	PPP3CA Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr12_-_56752366 Show fit	3.59	ENST00000672280.1	PRIM1 Ensembl NCBI GeneCards UniProt Show fit	DNA primase subunit 1
chr12_-_56752311 Show fit	3.58	ENST00000338193.11 ENST00000550770.1	PRIM1 Ensembl NCBI GeneCards UniProt Show fit	DNA primase subunit 1
chr16_+_56328661 Show fit	3.52	ENST00000562316.6	GNAO1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha o1
chr4_-_101347327 Show fit	3.48	ENST00000394853.8	PPP3CA Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr6_+_57090069 Show fit	3.29	ENST00000370708.8 ENST00000370702.5	ZNF451 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 451
chr12_+_6724071 Show fit	3.18	ENST00000229251.7 ENST00000539735.5 ENST00000538410.5	COPS7A Ensembl NCBI GeneCards UniProt Show fit	COP9 signalosome subunit 7A
chr12_+_32679200 Show fit	3.16	ENST00000452533.6 ENST00000414834.6	DNM1L Ensembl NCBI GeneCards UniProt Show fit	dynamin 1 like
chr12_+_32679269 Show fit	3.06	ENST00000358214.9 ENST00000553257.6 ENST00000549701.6 ENST00000266481.10 ENST00000551476.5 ENST00000550154.5 ENST00000547312.5 ENST00000381000.8 ENST00000548750.5	DNM1L Ensembl NCBI GeneCards UniProt Show fit	dynamin 1 like
chr5_-_83673544 Show fit	3.01	ENST00000503117.1 ENST00000510978.5	HAPLN1 Ensembl NCBI GeneCards UniProt Show fit	hyaluronan and proteoglycan link protein 1
chr6_+_34236865 Show fit	2.98	ENST00000674029.1 ENST00000447654.5 ENST00000347617.10 ENST00000401473.7 ENST00000311487.9	HMGA1 Ensembl NCBI GeneCards UniProt Show fit	high mobility group AT-hook 1
chr8_+_31639755 Show fit	2.96	ENST00000520407.5	NRG1 Ensembl NCBI GeneCards UniProt Show fit	neuregulin 1
chr12_+_6724008 Show fit	2.92	ENST00000626119.2 ENST00000543155.6	COPS7A Ensembl NCBI GeneCards UniProt Show fit	COP9 signalosome subunit 7A
chr7_-_100641507 Show fit	2.90	ENST00000431692.5 ENST00000223051.8	TFR2 Ensembl NCBI GeneCards UniProt Show fit	transferrin receptor 2
chr6_+_57090010 Show fit	2.84	ENST00000510483.5 ENST00000357489.7	ZNF451 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 451
chr1_-_151459471 Show fit	2.83	ENST00000271715.7	POGZ Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with ZNF domain
chr6_+_57090143 Show fit	2.73	ENST00000508603.5 ENST00000370706.9 ENST00000491832.6 ENST00000370710.10	ZNF451 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 451
chr17_-_2401038 Show fit	2.61	ENST00000174618.5 ENST00000575394.1	MNT Ensembl NCBI GeneCards UniProt Show fit	MAX network transcriptional repressor
chr18_+_32091849 Show fit	2.59	ENST00000261593.8 ENST00000578914.1	RNF138 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 138
chr4_-_101346842 Show fit	2.58	ENST00000507176.5	PPP3CA Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr11_+_112025968 Show fit	2.50	ENST00000680411.1	DLAT Ensembl NCBI GeneCards UniProt Show fit	dihydrolipoamide S-acetyltransferase
chr5_-_62403506 Show fit	2.43	ENST00000680062.1	DIMT1 Ensembl NCBI GeneCards UniProt Show fit	DIMT1 rRNA methyltransferase and ribosome maturation factor
chr1_-_151459169 Show fit	2.38	ENST00000368863.6 ENST00000409503.5 ENST00000491586.5 ENST00000533351.5	POGZ Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with ZNF domain
chr16_+_22490337 Show fit	2.38	ENST00000415833.6	NPIPB5 Ensembl NCBI GeneCards UniProt Show fit	nuclear pore complex interacting protein family member B5
chr7_-_23470469 Show fit	2.31	ENST00000258729.8	IGF2BP3 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 2 mRNA binding protein 3
chr17_-_39607876 Show fit	2.30	ENST00000302584.5	NEUROD2 Ensembl NCBI GeneCards UniProt Show fit	neuronal differentiation 2
chr8_+_32647080 Show fit	2.27	ENST00000520502.7 ENST00000523041.2 ENST00000650819.1	NRG1 Ensembl NCBI GeneCards UniProt Show fit	neuregulin 1
chrX_-_120559889 Show fit	2.26	ENST00000371323.3	CUL4B Ensembl NCBI GeneCards UniProt Show fit	cullin 4B
chr5_+_163460650 Show fit	2.22	ENST00000358715.3	HMMR Ensembl NCBI GeneCards UniProt Show fit	hyaluronan mediated motility receptor
chr14_-_20436161 Show fit	2.21	ENST00000636854.3	KLHL33 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 33
chr12_-_54259531 Show fit	2.19	ENST00000550411.5 ENST00000439541.6	CBX5 Ensembl NCBI GeneCards UniProt Show fit	chromobox 5
chr11_+_126327863 Show fit	2.16	ENST00000648516.1	DCPS Ensembl NCBI GeneCards UniProt Show fit	decapping enzyme, scavenger
chr5_+_163460623 Show fit	2.14	ENST00000393915.9 ENST00000432118.6	HMMR Ensembl NCBI GeneCards UniProt Show fit	hyaluronan mediated motility receptor
chr15_-_64381431 Show fit	2.13	ENST00000558008.3 ENST00000300035.9 ENST00000559519.5 ENST00000380258.6	PCLAF Ensembl NCBI GeneCards UniProt Show fit	PCNA clamp associated factor
chr18_+_58341038 Show fit	2.07	ENST00000679791.1	NEDD4L Ensembl NCBI GeneCards UniProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr14_+_61697622 Show fit	2.05	ENST00000539097.2	HIF1A Ensembl NCBI GeneCards UniProt Show fit	hypoxia inducible factor 1 subunit alpha
chr15_+_66386902 Show fit	2.05	ENST00000307102.10	MAP2K1 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase 1
chr14_-_22957128 Show fit	2.01	ENST00000342454.12 ENST00000555986.5 ENST00000554516.5 ENST00000347758.6 ENST00000206474.11 ENST00000555040.5	HAUS4 Ensembl NCBI GeneCards UniProt Show fit	HAUS augmin like complex subunit 4
chr16_+_7303245 Show fit	1.97	ENST00000674626.1	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr1_+_149475933 Show fit	1.93	ENST00000612881.4	NBPF19 Ensembl NCBI GeneCards UniProt Show fit	NBPF member 19
chr7_-_26200734 Show fit	1.93	ENST00000354667.8 ENST00000618183.5	HNRNPA2B1 Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein A2/B1
chr14_-_22957100 Show fit	1.85	ENST00000555367.5	HAUS4 Ensembl NCBI GeneCards UniProt Show fit	HAUS augmin like complex subunit 4
chr19_+_9087061 Show fit	1.82	ENST00000641627.1	OR1M1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 1 subfamily M member 1
chr3_-_142028617 Show fit	1.81	ENST00000477292.5 ENST00000478006.5 ENST00000495310.5 ENST00000486111.5	TFDP2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2
chr14_-_22957061 Show fit	1.78	ENST00000557591.5 ENST00000541587.6 ENST00000490506.5 ENST00000554406.1	HAUS4 Ensembl NCBI GeneCards UniProt Show fit	HAUS augmin like complex subunit 4
chr9_+_137241277 Show fit	1.78	ENST00000340384.5	TUBB4B Ensembl NCBI GeneCards UniProt Show fit	tubulin beta 4B class IVb
chr7_-_143362687 Show fit	1.76	ENST00000409578.5 ENST00000443739.7 ENST00000409346.5	FAM131B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 131 member B
chr8_+_132775340 Show fit	1.74	ENST00000622263.4 ENST00000220847.8 ENST00000395379.5 ENST00000395386.7 ENST00000485595.5 ENST00000337920.8	PHF20L1 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 20 like 1
chr10_-_125816596 Show fit	1.70	ENST00000368786.5	UROS Ensembl NCBI GeneCards UniProt Show fit	uroporphyrinogen III synthase
chr3_+_130931893 Show fit	1.70	ENST00000504612.5	ATP2C1 Ensembl NCBI GeneCards UniProt Show fit	ATPase secretory pathway Ca2+ transporting 1
chr2_-_49973939 Show fit	1.69	ENST00000630656.1	NRXN1 Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr19_+_7534242 Show fit	1.68	ENST00000545201.6	PNPLA6 Ensembl NCBI GeneCards UniProt Show fit	patatin like phospholipase domain containing 6
chr18_-_28036585 Show fit	1.65	ENST00000399380.7	CDH2 Ensembl NCBI GeneCards UniProt Show fit	cadherin 2
chr4_+_70721953 Show fit	1.60	ENST00000381006.8 ENST00000226328.8	RUFY3 Ensembl NCBI GeneCards UniProt Show fit	RUN and FYVE domain containing 3
chr8_-_18684033 Show fit	1.57	ENST00000614430.3	PSD3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing 3
chr8_-_18684093 Show fit	1.56	ENST00000428502.6	PSD3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing 3
chr3_-_120093666 Show fit	1.49	ENST00000316626.6 ENST00000650344.2 ENST00000678439.1	GSK3B Ensembl NCBI GeneCards UniProt Show fit	glycogen synthase kinase 3 beta
chr6_-_79078247 Show fit	1.48	ENST00000275034.5	PHIP Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain interacting protein
chr1_+_212035717 Show fit	1.48	ENST00000366991.5	DTL Ensembl NCBI GeneCards UniProt Show fit	denticleless E3 ubiquitin protein ligase homolog
chr9_-_41189310 Show fit	1.48	ENST00000456520.5 ENST00000377391.8 ENST00000613716.4 ENST00000617933.1	CBWD6 Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 6
chr8_+_53851786 Show fit	1.47	ENST00000297313.8 ENST00000344277.10	RGS20 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 20
chr1_+_146949314 Show fit	1.46	ENST00000617844.4 ENST00000611443.4	NBPF12 Ensembl NCBI GeneCards UniProt Show fit	NBPF member 12
chr3_+_40100007 Show fit	1.45	ENST00000539167.2	MYRIP Ensembl NCBI GeneCards UniProt Show fit	myosin VIIA and Rab interacting protein
chr3_-_187670385 Show fit	1.43	ENST00000287641.4	SST Ensembl NCBI GeneCards UniProt Show fit	somatostatin
chr5_+_161850597 Show fit	1.41	ENST00000634335.1 ENST00000635880.1	GABRA1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha1
chr11_-_10807345 Show fit	1.39	ENST00000525681.6	EIF4G2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4 gamma 2
chr6_+_158312459 Show fit	1.38	ENST00000367097.8	TULP4 Ensembl NCBI GeneCards UniProt Show fit	TUB like protein 4
chr1_+_198638968 Show fit	1.34	ENST00000348564.11 ENST00000530727.5 ENST00000442510.8 ENST00000645247.1 ENST00000367367.8 ENST00000367364.5 ENST00000413409.6	PTPRC Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type C
chr19_+_7534004 Show fit	1.31	ENST00000221249.10 ENST00000601668.5 ENST00000601001.5	PNPLA6 Ensembl NCBI GeneCards UniProt Show fit	patatin like phospholipase domain containing 6
chr2_+_165239432 Show fit	1.29	ENST00000636071.2 ENST00000636985.2	SCN2A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 2
chr22_-_35824373 Show fit	1.28	ENST00000473487.6	RBFOX2 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 2
chr10_-_119536533 Show fit	1.27	ENST00000392865.5	RGS10 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 10
chr17_+_81395469 Show fit	1.24	ENST00000584436.7	BAHCC1 Ensembl NCBI GeneCards UniProt Show fit	BAH domain and coiled-coil containing 1
chr2_-_49974083 Show fit	1.21	ENST00000636345.1	NRXN1 Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr17_+_81395449 Show fit	1.20	ENST00000675386.2	BAHCC1 Ensembl NCBI GeneCards UniProt Show fit	BAH domain and coiled-coil containing 1
chr1_+_207089233 Show fit	1.18	ENST00000243611.9 ENST00000367076.7	C4BPB Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr21_-_14546351 Show fit	1.14	ENST00000619120.4	SAMSN1 Ensembl NCBI GeneCards UniProt Show fit	SAM domain, SH3 domain and nuclear localization signals 1
chr11_-_35419098 Show fit	1.12	ENST00000606205.6 ENST00000645303.1	SLC1A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 2
chr12_+_100200779 Show fit	1.12	ENST00000188312.7 ENST00000546902.5 ENST00000552376.5 ENST00000551617.1	ACTR6 Ensembl NCBI GeneCards UniProt Show fit	actin related protein 6
chr7_-_78771265 Show fit	1.12	ENST00000630991.2 ENST00000629359.2	MAGI2 Ensembl NCBI GeneCards UniProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_-_13986439 Show fit	1.11	ENST00000443608.5 ENST00000438956.5	ETV1 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chr2_-_49974155 Show fit	1.11	ENST00000635519.1	NRXN1 Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr1_-_159714581 Show fit	1.09	ENST00000255030.9 ENST00000437342.1 ENST00000368112.5 ENST00000368111.5 ENST00000368110.1	CRP Ensembl NCBI GeneCards UniProt Show fit	C-reactive protein
chr14_-_54441325 Show fit	1.07	ENST00000556113.1 ENST00000553660.5 ENST00000216416.9 ENST00000395573.8 ENST00000557690.5	CNIH1 Ensembl NCBI GeneCards UniProt Show fit	cornichon family AMPA receptor auxiliary protein 1
chr2_-_55419565 Show fit	1.07	ENST00000647341.1 ENST00000647401.1 ENST00000336838.10 ENST00000621814.4 ENST00000644033.1 ENST00000645477.1 ENST00000647517.1	CCDC88A Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr11_-_790062 Show fit	1.06	ENST00000330106.5	CEND1 Ensembl NCBI GeneCards UniProt Show fit	cell cycle exit and neuronal differentiation 1
chr5_+_66144288 Show fit	1.05	ENST00000334121.11	SREK1 Ensembl NCBI GeneCards UniProt Show fit	splicing regulatory glutamic acid and lysine rich protein 1
chr19_+_35449584 Show fit	1.04	ENST00000246549.2	FFAR2 Ensembl NCBI GeneCards UniProt Show fit	free fatty acid receptor 2
chr5_-_9630351 Show fit	1.04	ENST00000382492.4	TAS2R1 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 1
chr3_-_79019444 Show fit	1.03	ENST00000618833.4 ENST00000436010.6 ENST00000618846.4	ROBO1 Ensembl NCBI GeneCards UniProt Show fit	roundabout guidance receptor 1
chr21_-_14546297 Show fit	1.02	ENST00000400566.6 ENST00000400564.5	SAMSN1 Ensembl NCBI GeneCards UniProt Show fit	SAM domain, SH3 domain and nuclear localization signals 1
chr5_+_139561159 Show fit	1.01	ENST00000505007.5	UBE2D2 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D2
chr11_-_35418966 Show fit	0.97	ENST00000531628.2	SLC1A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 2
chr1_+_207089283 Show fit	0.95	ENST00000391923.1	C4BPB Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr11_-_116787979 Show fit	0.91	ENST00000429220.5 ENST00000444935.5 ENST00000227322.8	ZPR1 Ensembl NCBI GeneCards UniProt Show fit	ZPR1 zinc finger
chr2_-_49974182 Show fit	0.91	ENST00000412315.5 ENST00000378262.7	NRXN1 Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr11_+_63369779 Show fit	0.88	ENST00000279178.4	SLC22A9 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22 member 9
chr7_-_51316754 Show fit	0.87	ENST00000632460.1 ENST00000441453.5 ENST00000648294.1 ENST00000265136.12 ENST00000395542.6 ENST00000395540.6	COBL Ensembl NCBI GeneCards UniProt Show fit	cordon-bleu WH2 repeat protein
chr1_+_92168915 Show fit	0.86	ENST00000637221.2	BTBD8 Ensembl NCBI GeneCards UniProt Show fit	BTB domain containing 8
chr2_-_55419276 Show fit	0.85	ENST00000646796.1	CCDC88A Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr6_+_52420992 Show fit	0.85	ENST00000636954.1 ENST00000636566.1 ENST00000638075.1	EFHC1 Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain containing 1
chr11_-_35419213 Show fit	0.83	ENST00000642171.1 ENST00000644050.1 ENST00000643134.1	SLC1A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 2
chr11_-_60855943 Show fit	0.80	ENST00000332539.5	PTGDR2 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin D2 receptor 2
chr19_+_926001 Show fit	0.78	ENST00000263620.8	ARID3A Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 3A
chr18_+_11752041 Show fit	0.73	ENST00000423027.8	GNAL Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha L
chr2_+_165239388 Show fit	0.73	ENST00000424833.5 ENST00000375437.7 ENST00000631182.3	SCN2A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 2
chr2_+_108588286 Show fit	0.72	ENST00000332345.10	LIMS1 Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 1
chr3_+_39383337 Show fit	0.70	ENST00000650617.1 ENST00000431510.1 ENST00000645630.1	SLC25A38 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 38
chr20_-_1994046 Show fit	0.70	ENST00000217305.3 ENST00000650874.1	PDYN Ensembl NCBI GeneCards UniProt Show fit	prodynorphin
chr5_+_139561308 Show fit	0.69	ENST00000398733.8	UBE2D2 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D2
chr17_+_7558296 Show fit	0.67	ENST00000438470.5 ENST00000436057.5	TNFSF13 Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 13
chr12_+_20695323 Show fit	0.63	ENST00000266509.7	SLCO1C1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 1C1
chr2_+_6877768 Show fit	0.61	ENST00000382040.4	RSAD2 Ensembl NCBI GeneCards UniProt Show fit	radical S-adenosyl methionine domain containing 2
chr14_+_19743571 Show fit	0.61	ENST00000642117.2	OR4Q3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 4 subfamily Q member 3
chr1_+_154405193 Show fit	0.59	ENST00000622330.4 ENST00000344086.8	IL6R Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 receptor
chr1_+_192636121 Show fit	0.58	ENST00000543215.5 ENST00000391995.7	RGS13 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 13
chr6_+_37433197 Show fit	0.57	ENST00000455891.5 ENST00000373451.9	CMTR1 Ensembl NCBI GeneCards UniProt Show fit	cap methyltransferase 1
chrX_+_46912276 Show fit	0.56	ENST00000424392.5 ENST00000611250.4	JADE3 Ensembl NCBI GeneCards UniProt Show fit	jade family PHD finger 3
chr1_+_207089195 Show fit	0.56	ENST00000452902.6	C4BPB Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr7_+_80602150 Show fit	0.53	ENST00000309881.11	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr16_+_56191728 Show fit	0.51	ENST00000638705.1 ENST00000262494.12	GNAO1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha o1
chr7_-_151633182 Show fit	0.51	ENST00000476632.2	PRKAG2 Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit gamma 2
chr5_+_148394712 Show fit	0.49	ENST00000513826.1	FBXO38 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 38
chr8_-_85378105 Show fit	0.48	ENST00000521846.5 ENST00000523022.6 ENST00000524324.5 ENST00000519991.5 ENST00000520663.5 ENST00000517590.5 ENST00000522579.5 ENST00000522814.5 ENST00000522662.5 ENST00000523858.5 ENST00000519129.5	CA1 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 1
chr9_+_74615582 Show fit	0.48	ENST00000396204.2	RORB Ensembl NCBI GeneCards UniProt Show fit	RAR related orphan receptor B
chrX_+_10156960 Show fit	0.48	ENST00000380833.9	CLCN4 Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel 4
chr1_-_158554405 Show fit	0.48	ENST00000641282.1 ENST00000641622.1	OR6Y1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 6 subfamily Y member 1
chr16_+_28751787 Show fit	0.48	ENST00000357796.7 ENST00000550983.1	NPIPB9 Ensembl NCBI GeneCards UniProt Show fit	nuclear pore complex interacting protein family member B9
chr11_-_124445696 Show fit	0.47	ENST00000642064.1	OR8B8 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 8 subfamily B member 8
chr8_-_107497909 Show fit	0.45	ENST00000517746.6	ANGPT1 Ensembl NCBI GeneCards UniProt Show fit	angiopoietin 1
chr7_+_120273129 Show fit	0.44	ENST00000331113.9	KCND2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily D member 2
chr12_+_55362975 Show fit	0.43	ENST00000641576.1	OR6C75 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 6 subfamily C member 75
chr9_-_74952904 Show fit	0.41	ENST00000376854.6	C9orf40 Ensembl NCBI GeneCards UniProt Show fit	chromosome 9 open reading frame 40
chrX_+_46912412 Show fit	0.40	ENST00000614628.5	JADE3 Ensembl NCBI GeneCards UniProt Show fit	jade family PHD finger 3
chr1_-_959240 Show fit	0.38	ENST00000327044.7	NOC2L Ensembl NCBI GeneCards UniProt Show fit	NOC2 like nucleolar associated transcriptional repressor
chr2_+_156473569 Show fit	0.38	ENST00000409674.5 ENST00000409125.8	GPD2 Ensembl NCBI GeneCards UniProt Show fit	glycerol-3-phosphate dehydrogenase 2
chrX_-_64976500 Show fit	0.37	ENST00000447788.6	ZC4H2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger C4H2-type containing
chr7_+_80602200 Show fit	0.36	ENST00000534394.5	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr3_-_171026709 Show fit	0.36	ENST00000314251.8	SLC2A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 2 member 2
chr16_+_25216943 Show fit	0.35	ENST00000219660.6	AQP8 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 8
chrX_-_64976435 Show fit	0.34	ENST00000374839.8	ZC4H2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger C4H2-type containing
chr17_-_41467386 Show fit	0.33	ENST00000225899.4	KRT32 Ensembl NCBI GeneCards UniProt Show fit	keratin 32
chr11_+_95066913 Show fit	0.32	ENST00000587424.3	SRSF8 Ensembl NCBI GeneCards UniProt Show fit	serine and arginine rich splicing factor 8
chr12_+_85874287 Show fit	0.31	ENST00000551529.5 ENST00000256010.7	NTS Ensembl NCBI GeneCards UniProt Show fit	neurotensin
chr4_+_186266183 Show fit	0.31	ENST00000403665.7 ENST00000492972.6 ENST00000264692.8	F11 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor XI
chr2_+_108588453 Show fit	0.31	ENST00000393310.5	LIMS1 Ensembl NCBI GeneCards UniProt Show fit	LIM zinc finger domain containing 1
chr4_+_155903688 Show fit	0.31	ENST00000536354.3	TDO2 Ensembl NCBI GeneCards UniProt Show fit	tryptophan 2,3-dioxygenase
chr12_-_7665897 Show fit	0.30	ENST00000229304.5	APOBEC1 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 1
chr1_+_159587817 Show fit	0.27	ENST00000255040.3	APCS Ensembl NCBI GeneCards UniProt Show fit	amyloid P component, serum
chr7_-_13986498 Show fit	0.25	ENST00000420159.6 ENST00000399357.7 ENST00000403527.5	ETV1 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chr2_+_170178136 Show fit	0.24	ENST00000409044.7 ENST00000408978.9	MYO3B Ensembl NCBI GeneCards UniProt Show fit	myosin IIIB
chr1_-_53220589 Show fit	0.24	ENST00000294360.5	CZIB Ensembl NCBI GeneCards UniProt Show fit	CXXC motif containing zinc binding protein
chr1_-_29230871 Show fit	0.24	ENST00000373791.7 ENST00000263702.11	MECR Ensembl NCBI GeneCards UniProt Show fit	mitochondrial trans-2-enoyl-CoA reductase
chr16_-_49856105 Show fit	0.23	ENST00000563137.7	ZNF423 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 423
chr5_-_144170607 Show fit	0.23	ENST00000448443.6 ENST00000513112.5 ENST00000519064.5 ENST00000274496.10 ENST00000522203.5	YIPF5 Ensembl NCBI GeneCards UniProt Show fit	Yip1 domain family member 5
chr7_-_5959083 Show fit	0.22	ENST00000539903.5	RSPH10B Ensembl NCBI GeneCards UniProt Show fit	radial spoke head 10 homolog B
chr12_+_4590075 Show fit	0.20	ENST00000540757.6	DYRK4 Ensembl NCBI GeneCards UniProt Show fit	dual specificity tyrosine phosphorylation regulated kinase 4
chr6_+_13013513 Show fit	0.19	ENST00000675203.1	PHACTR1 Ensembl NCBI GeneCards UniProt Show fit	phosphatase and actin regulator 1
chr1_-_110607970 Show fit	0.15	ENST00000638532.1	KCNA2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A member 2
chr6_+_29100609 Show fit	0.12	ENST00000377171.3	OR2J1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily J member 1
chr1_-_110607816 Show fit	0.11	ENST00000485317.6	KCNA2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A member 2
chr2_+_33436304 Show fit	0.09	ENST00000402538.7	RASGRP3 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 3
chr5_-_147453888 Show fit	0.08	ENST00000398514.7	DPYSL3 Ensembl NCBI GeneCards UniProt Show fit	dihydropyrimidinase like 3
chr12_+_41437680 Show fit	0.08	ENST00000649474.1 ENST00000539469.6 ENST00000298919.7	PDZRN4 Ensembl NCBI GeneCards UniProt Show fit	PDZ domain containing ring finger 4
chr10_-_96271553 Show fit	0.05	ENST00000224337.10	BLNK Ensembl NCBI GeneCards UniProt Show fit	B cell linker
chr2_+_169584385 Show fit	0.05	ENST00000462903.6 ENST00000676756.1	PPIG Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase G
chr2_-_39121000 Show fit	0.04	ENST00000402219.8	SOS1 Ensembl NCBI GeneCards UniProt Show fit	SOS Ras/Rac guanine nucleotide exchange factor 1
chr15_-_37100523 Show fit	0.03	ENST00000424352.6 ENST00000561208.6	MEIS2 Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 2
chr2_-_24328113 Show fit	0.02	ENST00000622089.4	ITSN2 Ensembl NCBI GeneCards UniProt Show fit	intersectin 2
chr3_-_194398354 Show fit	0.01	ENST00000401815.1	GP5 Ensembl NCBI GeneCards UniProt Show fit	glycoprotein V platelet
chr12_+_64452084 Show fit	0.01	ENST00000677641.1 ENST00000650790.1 ENST00000652657.1 ENST00000676912.1 ENST00000677545.1 ENST00000677632.1 ENST00000331710.10 ENST00000678180.1 ENST00000650762.1 ENST00000676930.1 ENST00000651014.1 ENST00000538890.5	TBK1 Ensembl NCBI GeneCards UniProt Show fit	TANK binding kinase 1
chrX_-_19970298 Show fit	0.01	ENST00000379687.7 ENST00000379682.8	BCLAF3 Ensembl NCBI GeneCards UniProt Show fit	BCLAF1 and THRAP3 family member 3
chr16_-_8868343 Show fit	0.00	ENST00000562843.5 ENST00000561530.5 ENST00000396593.6	CARHSP1 Ensembl NCBI GeneCards UniProt Show fit	calcium regulated heat stable protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	13.3	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
3.0	8.9	GO:2000616	negative regulation of histone H3-K9 acetylation(GO:2000616)
2.1	6.2	GO:0036466	synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
1.8	7.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
1.0	3.0	GO:0090402	oncogene-induced cell senescence(GO:0090402)
0.7	2.2	GO:0036245	cellular response to menadione(GO:0036245)
0.7	3.9	GO:0035063	nuclear speck organization(GO:0035063)
0.6	2.3	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.5	1.0	GO:0021836	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.5	1.5	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.5	2.9	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4	1.3	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.4	4.9	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.4	5.2	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.4	1.7	GO:0071418	cellular response to amine stimulus(GO:0071418)
0.4	6.1	GO:0000338	protein deneddylation(GO:0000338)
0.4	2.6	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3	1.0	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3	2.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.3	2.7	GO:0030450	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.3	1.9	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.3	5.2	GO:0051382	kinetochore assembly(GO:0051382)
0.3	2.1	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.3	0.9	GO:0001757	somite specification(GO:0001757)
0.3	1.4	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.3	1.7	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.3	14.3	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.3	1.9	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.3	2.8	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2	2.4	GO:0031507	heterochromatin assembly(GO:0031507)
0.2	3.7	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.2	0.7	GO:0036233	glycine import(GO:0036233)
0.2	1.1	GO:0021590	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.2	0.8	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.2	10.5	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.2	8.4	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2	2.9	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2	1.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.2	0.9	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.2	2.1	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2	6.6	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2	2.0	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1	0.6	GO:0002384	hepatic immune response(GO:0002384)
0.1	2.5	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	4.4	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.1	0.4	GO:0035691	macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1	0.6	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.1	0.4	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	2.3	GO:0070914	UV-damage excision repair(GO:0070914)
0.1	3.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.9	GO:0015747	urate transport(GO:0015747)
0.1	1.5	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.1	3.0	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.1	0.9	GO:0070543	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1	0.6	GO:0080009	mRNA methylation(GO:0080009)
0.1	2.4	GO:0031167	rRNA methylation(GO:0031167)
0.1	1.1	GO:0008228	opsonization(GO:0008228)
0.1	0.3	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
0.1	1.4	GO:0007638	mechanosensory behavior(GO:0007638)
0.1	0.5	GO:0035881	amacrine cell differentiation(GO:0035881)
0.1	0.4	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.1	1.5	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1	1.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.1	1.3	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	15.1	GO:0030307	positive regulation of cell growth(GO:0030307)
0.1	9.7	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	3.6	GO:0019985	translesion synthesis(GO:0019985)
0.1	4.4	GO:0016445	somatic diversification of immunoglobulins(GO:0016445)
0.1	2.2	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
0.1	0.4	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.1	1.4	GO:0071420	cellular response to histamine(GO:0071420)
0.1	0.3	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.3	GO:0016554	cytidine to uridine editing(GO:0016554) DNA cytosine deamination(GO:0070383) regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0	0.6	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	5.6	GO:0051225	spindle assembly(GO:0051225)
0.0	1.0	GO:0007635	chemosensory behavior(GO:0007635)
0.0	2.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	3.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	1.7	GO:0035666	TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0	3.6	GO:0007569	cell aging(GO:0007569)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.4	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.7	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	1.8	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.5	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.7	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.0	1.9	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.0	0.2	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.8	GO:1902400	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	1.1	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.3	GO:0006833	water transport(GO:0006833)
0.0	0.5	GO:1903959	regulation of anion transmembrane transport(GO:1903959)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	8.4	GO:0098843	postsynaptic endocytic zone(GO:0098843)
1.2	13.3	GO:0005955	calcineurin complex(GO:0005955)
1.2	7.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.6	5.6	GO:0070652	HAUS complex(GO:0070652)
0.4	3.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.4	2.5	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3	3.7	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2	4.5	GO:0000974	Prp19 complex(GO:0000974)
0.2	2.9	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.2	2.4	GO:0005677	chromatin silencing complex(GO:0005677)
0.2	3.7	GO:0043219	lateral loop(GO:0043219)
0.2	2.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.2	7.8	GO:0030673	axolemma(GO:0030673)
0.2	1.5	GO:1990909	Wnt signalosome(GO:1990909)
0.2	11.3	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	2.0	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.4	GO:0030689	Noc complex(GO:0030689)
0.1	0.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	6.1	GO:0008180	COP9 signalosome(GO:0008180)
0.1	0.9	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.1	0.9	GO:0044294	dendritic growth cone(GO:0044294)
0.1	1.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1	1.5	GO:0000145	exocyst(GO:0000145)
0.1	1.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	2.6	GO:0035861	site of double-strand break(GO:0035861)
0.1	6.2	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	8.9	GO:0016605	PML body(GO:0016605)
0.1	0.4	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	20.7	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	1.6	GO:0071437	invadopodium(GO:0071437)
0.0	1.4	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	2.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	2.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	2.1	GO:0005771	multivesicular body(GO:0005771)
0.0	1.5	GO:0015030	Cajal body(GO:0015030)
0.0	0.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	2.7	GO:0044215	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	5.1	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	2.3	GO:0043679	axon terminus(GO:0043679)
0.0	1.9	GO:0042734	presynaptic membrane(GO:0042734)
0.0	7.9	GO:0005769	early endosome(GO:0005769)
0.0	0.4	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	1.6	GO:0036064	ciliary basal body(GO:0036064)
0.0	2.9	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	1.8	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.9	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	7.6	GO:0045202	synapse(GO:0045202)
0.0	1.0	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.0	0.2	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	4.3	GO:0000790	nuclear chromatin(GO:0000790)
0.0	1.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	7.2	GO:0003896	DNA primase activity(GO:0003896)
1.5	13.3	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
1.5	8.9	GO:0061665	SUMO ligase activity(GO:0061665)
1.1	9.7	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
1.0	8.4	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
1.0	2.9	GO:0004998	transferrin receptor activity(GO:0004998)
0.8	2.4	GO:0008988	rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.7	10.5	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.6	2.5	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.4	1.7	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.3	6.2	GO:0051400	BH domain binding(GO:0051400)
0.3	5.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3	1.1	GO:0033265	choline binding(GO:0033265)
0.3	0.8	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.2	1.4	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2	3.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.2	2.2	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.2	2.9	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.2	4.9	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.2	3.7	GO:0097016	L27 domain binding(GO:0097016)
0.2	0.6	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
0.2	7.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.2	1.9	GO:0097157	pre-mRNA intronic binding(GO:0097157) N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.6	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	1.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.4	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	2.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.9	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.1	3.9	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	0.3	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	0.7	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.1	0.7	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.9	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	3.0	GO:0004622	lysophospholipase activity(GO:0004622)
0.1	1.0	GO:0033038	bitter taste receptor activity(GO:0033038)
0.1	0.4	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1	3.1	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	1.9	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.6	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.2	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	2.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	17.9	GO:0005057	receptor signaling protein activity(GO:0005057)
0.1	2.0	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	1.6	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	2.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	1.7	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	1.5	GO:0050321	protein kinase A catalytic subunit binding(GO:0034236) tau-protein kinase activity(GO:0050321)
0.1	0.5	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	1.8	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	0.4	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.3	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.5	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.5	GO:0005549	odorant binding(GO:0005549)
0.0	1.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	1.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	2.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.3	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	2.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	1.5	GO:0051018	protein kinase A binding(GO:0051018)
0.0	1.5	GO:0005158	insulin receptor binding(GO:0005158)
0.0	3.2	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	1.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.5	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.9	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.9	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0015250	water channel activity(GO:0015250)
0.0	0.7	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	2.3	GO:0003684	damaged DNA binding(GO:0003684)
0.0	2.2	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	5.7	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	1.7	GO:0005179	hormone activity(GO:0005179)
0.0	0.6	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	10.5	PID S1P S1P4 PATHWAY	S1P4 pathway
0.3	9.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.2	13.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	5.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	8.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	1.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	2.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	1.9	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	8.8	PID E2F PATHWAY	E2F transcription factor network
0.1	3.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	1.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	10.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.6	ST STAT3 PATHWAY	STAT3 Pathway
0.0	3.0	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	1.7	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	2.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.4	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	1.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.4	PID SHP2 PATHWAY	SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	7.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.3	8.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3	3.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3	10.5	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2	13.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.2	4.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	2.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	7.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	2.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	3.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	3.6	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	1.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	0.7	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.7	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	1.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	4.3	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
0.0	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	3.1	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	1.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	2.9	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	1.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	2.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	2.3	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	3.5	REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	Genes involved in Class I MHC mediated antigen processing & presentation
0.0	1.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing

Results for ONECUT2_ONECUT3

Z-value: 0.64

Motif logo

Transcription factors associated with ONECUT2_ONECUT3

Activity-expression correlation:

Activity profile of ONECUT2_ONECUT3 motif

Sorted Z-values of ONECUT2_ONECUT3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT2_ONECUT3

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: