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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PAX7_NOBOX

Z-value: 0.90

Motif logo

Transcription factors associated with PAX7_NOBOX

Gene Symbol Gene ID Gene Info
ENSG00000009709.12 PAX7
ENSG00000106410.15 NOBOX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX7hg38_v1_chr1_+_18631513_186315290.485.8e-14Click!

Activity profile of PAX7_NOBOX motif

Sorted Z-values of PAX7_NOBOX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX7_NOBOX

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_91153149 25.52 ENST00000550758.1
decorin
chr17_+_1771688 20.20 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr19_+_49513353 17.55 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr10_-_97445850 13.64 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
exosome component 1
chr11_+_95789965 12.96 ENST00000537677.5
centrosomal protein 57
chr2_+_90209873 12.89 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr9_-_95317671 12.87 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FA complementation group C
chr18_+_31591869 12.79 ENST00000237014.8
transthyretin
chr2_+_68734861 12.27 ENST00000467265.5
Rho GTPase activating protein 25
chr2_+_68734773 11.29 ENST00000409202.8
Rho GTPase activating protein 25
chr7_+_100539188 10.75 ENST00000300176.9
ArfGAP with FG repeats 2
chr6_-_31158073 10.23 ENST00000507751.5
ENST00000448162.6
ENST00000502557.5
ENST00000503420.5
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.5
ENST00000396263.6
ENST00000508683.5
ENST00000428174.1
ENST00000448141.6
ENST00000507829.5
ENST00000455279.6
ENST00000376266.9
coiled-coil alpha-helical rod protein 1
chr14_-_52069039 10.14 ENST00000216286.10
nidogen 2
chr5_+_177426701 9.71 ENST00000507633.5
ENST00000393576.7
ENST00000355958.9
ENST00000528793.5
ENST00000512684.1
G protein-coupled receptor kinase 6
chr12_+_26195313 9.61 ENST00000422622.3
sarcospan
chr2_+_89884740 9.20 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr1_-_92486916 9.01 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr14_-_52069228 8.97 ENST00000617139.4
nidogen 2
chr2_+_90038848 8.77 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr5_+_177426667 8.58 ENST00000355472.10
G protein-coupled receptor kinase 6
chr1_+_100351698 8.52 ENST00000644676.1
cell division cycle 14A
chr1_+_110873135 8.45 ENST00000271324.6
CD53 molecule
chrX_+_43656289 8.26 ENST00000338702.4
monoamine oxidase A
chr5_-_95961830 8.20 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr5_+_40909490 8.16 ENST00000313164.10
complement C7
chr8_-_39838201 8.07 ENST00000347580.8
ENST00000379853.6
ENST00000265708.9
ENST00000521880.5
ADAM metallopeptidase domain 2
chr14_-_74493291 7.98 ENST00000238633.6
ENST00000555619.6
ENST00000434013.6
NPC intracellular cholesterol transporter 2
chr5_+_67004618 7.97 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr14_-_74493275 7.97 ENST00000541064.5
NPC intracellular cholesterol transporter 2
chr14_-_74084393 7.85 ENST00000350259.8
ENST00000553458.6
aldehyde dehydrogenase 6 family member A1
chr11_+_57597563 7.78 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr14_-_74493322 7.57 ENST00000553490.5
ENST00000557510.5
NPC intracellular cholesterol transporter 2
chrX_+_10158448 7.24 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chrX_+_136205982 7.23 ENST00000628568.1
four and a half LIM domains 1
chr11_-_59615673 7.07 ENST00000263847.6
oxysterol binding protein
chr16_-_66550005 7.06 ENST00000527284.6
thymidine kinase 2
chr11_+_76445001 7.03 ENST00000533988.5
ENST00000524490.5
ENST00000334736.7
ENST00000533972.5
EMSY transcriptional repressor, BRCA2 interacting
chr1_+_12019460 7.01 ENST00000235332.6
migration and invasion inhibitory protein
chr14_+_74084947 6.98 ENST00000674221.1
ENST00000554938.2
lin-52 DREAM MuvB core complex component
chr6_+_26402237 6.91 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr14_-_24609660 6.78 ENST00000557220.6
ENST00000216338.9
ENST00000382548.4
granzyme H
chr6_-_32128191 6.57 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
activating transcription factor 6 beta
chr16_-_66550091 6.37 ENST00000564917.5
ENST00000677420.1
thymidine kinase 2
chr4_-_46909235 6.36 ENST00000505102.1
ENST00000355591.8
cytochrome c oxidase subunit 7B2
chr3_-_105869035 6.34 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr22_-_21735776 6.30 ENST00000339468.8
yippee like 1
chr1_+_1324790 6.23 ENST00000343938.9
ceramide-1-phosphate transfer protein
chr22_-_21735744 6.18 ENST00000403503.1
yippee like 1
chr1_-_150765785 6.09 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr2_+_87338511 5.91 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr16_+_72063226 5.88 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
haptoglobin-related protein
chr3_+_46370854 5.85 ENST00000292303.4
C-C motif chemokine receptor 5
chr16_+_3443645 5.82 ENST00000572757.5
ENST00000573593.5
ENST00000570372.5
ENST00000407558.9
ENST00000424546.6
ENST00000575733.5
ENST00000649205.1
ENST00000574950.5
ENST00000573580.5
ENST00000572169.6
ENST00000649360.1
N-alpha-acetyltransferase 60, NatF catalytic subunit
chr7_+_100586304 5.76 ENST00000241071.11
F-box protein 24
chr19_-_19192122 5.71 ENST00000444486.7
ENST00000514819.7
ENST00000585679.1
ENST00000462790.8
myocyte enhancer factor 2B
BORCS8-MEF2B readthrough
BLOC-1 related complex subunit 8
chr4_-_145180496 5.58 ENST00000447906.8
OTU deubiquitinase 4
chr12_-_9999176 5.54 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr4_-_46909206 5.37 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr3_-_105868964 5.08 ENST00000394030.8
Cbl proto-oncogene B
chr1_-_183590876 5.08 ENST00000367536.5
neutrophil cytosolic factor 2
chr2_+_90234809 5.07 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr4_-_56681588 5.05 ENST00000554144.5
ENST00000381260.7
HOP homeobox
chr18_-_14132423 5.04 ENST00000589498.5
ENST00000590202.3
zinc finger protein 519
chr1_+_43650118 4.97 ENST00000372396.4
lysine demethylase 4A
chr14_-_103715433 4.96 ENST00000554913.5
ENST00000555055.6
ENST00000554974.5
ENST00000553361.5
ENST00000555964.5
ENST00000556682.5
ENST00000553332.5
ENST00000352127.11
X-ray repair cross complementing 3
chr4_-_39032343 4.93 ENST00000381938.4
transmembrane protein 156
chr16_-_66550142 4.92 ENST00000417693.8
ENST00000299697.12
ENST00000451102.7
thymidine kinase 2
chr19_-_40413364 4.91 ENST00000291825.11
ENST00000324001.8
periaxin
chr4_+_94974984 4.91 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr10_-_17129786 4.87 ENST00000377833.10
cubilin
chr16_-_66549839 4.77 ENST00000527800.6
ENST00000677555.1
ENST00000563369.6
thymidine kinase 2
chr10_-_28282086 4.73 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr2_+_90172802 4.72 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr4_-_56681288 4.70 ENST00000556376.6
ENST00000420433.6
HOP homeobox
chr1_-_91906280 4.70 ENST00000370399.6
transforming growth factor beta receptor 3
chr2_-_162152404 4.65 ENST00000375497.3
glucagon
chr2_+_90069662 4.63 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_-_88979016 4.61 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr19_-_53254841 4.59 ENST00000601828.5
ENST00000599012.5
ENST00000598513.6
ENST00000598806.5
zinc finger protein 677
chr4_+_73409340 4.59 ENST00000511370.1
albumin
chr1_-_1324630 4.57 ENST00000434694.6
ENST00000421495.6
ENST00000419704.5
ENST00000530031.5
ENST00000435064.6
ENST00000526332.5
ENST00000498476.6
ENST00000429572.5
ENST00000450926.6
ENST00000527719.5
ENST00000534345.5
ENST00000411962.5
ENST00000540437.5
ENST00000545578.5
ENST00000620829.4
ENST00000618806.4
integrator complex subunit 11
chr12_-_9869345 4.56 ENST00000228438.3
C-type lectin domain family 2 member B
chr19_+_49513154 4.51 ENST00000426395.7
ENST00000600273.5
ENST00000599988.5
Fc fragment of IgG receptor and transporter
chr9_-_21368962 4.46 ENST00000610660.1
interferon alpha 13
chr16_-_55833085 4.42 ENST00000360526.8
carboxylesterase 1
chr11_-_108222594 4.42 ENST00000278612.9
nuclear protein, coactivator of histone transcription
chr3_-_161105224 4.41 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chrX_+_37780049 4.38 ENST00000378588.5
cytochrome b-245 beta chain
chr6_+_26402289 4.37 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr15_+_58138368 4.36 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr16_-_66550112 4.36 ENST00000544898.6
ENST00000620035.5
ENST00000545043.6
thymidine kinase 2
chr10_-_97687191 4.35 ENST00000370626.4
arginine vasopressin induced 1
chr6_+_26440472 4.34 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr6_-_52840843 4.32 ENST00000370989.6
glutathione S-transferase alpha 5
chr22_+_41381923 4.31 ENST00000266304.9
TEF transcription factor, PAR bZIP family member
chr8_-_30812867 4.31 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr1_+_157993273 4.29 ENST00000360089.8
ENST00000368173.7
kirre like nephrin family adhesion molecule 1
chr16_-_28623560 4.29 ENST00000350842.8
sulfotransferase family 1A member 1
chr6_-_166627244 4.15 ENST00000265678.9
ribosomal protein S6 kinase A2
chr17_-_81860478 4.13 ENST00000681693.1
ENST00000680226.1
ENST00000679439.1
ENST00000576390.6
ENST00000570907.6
ENST00000680191.1
ENST00000681020.1
ENST00000571617.2
ENST00000415593.6
ENST00000331483.9
ENST00000680914.1
ENST00000680593.1
ENST00000439918.7
ENST00000574914.2
ENST00000681161.1
ENST00000680884.1
prolyl 4-hydroxylase subunit beta
chr5_+_131170936 4.10 ENST00000510516.5
ENST00000379380.9
ENST00000507584.1
LYR motif containing 7
chrX_+_139530730 3.76 ENST00000218099.7
coagulation factor IX
chr11_-_117877463 3.72 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr3_+_47282930 3.72 ENST00000232766.6
ENST00000437353.5
kelch like family member 18
chr4_+_155666718 3.72 ENST00000621234.4
ENST00000511108.5
guanylate cyclase 1 soluble subunit alpha 1
chr14_-_24242600 3.66 ENST00000646753.1
ENST00000558566.1
ENST00000267415.12
ENST00000559019.1
ENST00000399423.8
ENST00000626689.2
TERF1 interacting nuclear factor 2
chr8_-_39838250 3.65 ENST00000622267.1
ADAM metallopeptidase domain 2
chrX_-_17861236 3.64 ENST00000331511.5
ENST00000415486.7
ENST00000451717.6
ENST00000545871.1
retinoic acid induced 2
chr16_+_31259922 3.57 ENST00000648685.1
ENST00000544665.9
integrin subunit alpha M
chrX_-_119943732 3.50 ENST00000371410.5
NFKB activating protein
chr12_+_26195543 3.48 ENST00000242729.7
sarcospan
chr7_-_100586119 3.48 ENST00000310300.11
leucine rich repeats and calponin homology domain containing 4
chr8_+_9555900 3.48 ENST00000310430.11
ENST00000520408.5
ENST00000522110.1
tankyrase
chr19_+_4007714 3.48 ENST00000262971.3
protein inhibitor of activated STAT 4
chr1_-_161021096 3.47 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr6_-_119149124 3.46 ENST00000368475.8
family with sequence similarity 184 member A
chr3_+_129528632 3.44 ENST00000296271.4
rhodopsin
chr1_-_48472166 3.44 ENST00000371847.8
ENST00000396199.7
spermatogenesis associated 6
chr1_-_13285154 3.39 ENST00000357367.6
ENST00000614831.1
PRAME family member 8
chr12_-_114403898 3.38 ENST00000526441.1
T-box transcription factor 5
chr7_-_36724543 3.36 ENST00000612871.4
acyloxyacyl hydrolase
chr1_+_12773738 3.34 ENST00000357726.5
PRAME family member 12
chr6_-_26271815 3.32 ENST00000614378.1
H3 clustered histone 8
chr15_-_77420135 3.29 ENST00000560626.6
pseudopodium enriched atypical kinase 1
chr5_+_142770367 3.27 ENST00000645722.2
ENST00000274498.9
Rho GTPase activating protein 26
chr17_-_44968263 3.25 ENST00000253407.4
complement C1q like 1
chr6_+_160702238 3.23 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chrX_-_154097731 3.22 ENST00000628176.2
methyl-CpG binding protein 2
chr12_+_112125531 3.22 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr12_-_21910853 3.22 ENST00000544039.5
ATP binding cassette subfamily C member 9
chr19_+_49487510 3.20 ENST00000679106.1
ENST00000621674.4
ENST00000391857.9
ENST00000678510.1
ENST00000467825.2
ribosomal protein L13a
chr7_+_116222804 3.19 ENST00000393481.6
testin LIM domain protein
chr22_-_38794111 3.18 ENST00000406622.5
ENST00000216068.9
ENST00000406199.3
Sad1 and UNC84 domain containing 2
dynein axonemal light chain 4
chr14_+_103715767 3.13 ENST00000311141.7
zinc finger FYVE-type containing 21
chr9_-_101430861 3.13 ENST00000649902.1
aldolase, fructose-bisphosphate B
chr14_-_106593319 3.11 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr7_+_93906557 3.11 ENST00000248572.10
ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
G protein subunit gamma transducin 1
chr19_+_36605292 3.06 ENST00000460670.5
ENST00000292928.7
ENST00000439428.5
zinc finger protein 382
chr19_-_12722547 3.05 ENST00000592287.5
transportin 2
chr4_+_87832917 3.00 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr1_-_48400826 2.99 ENST00000371841.1
spermatogenesis associated 6
chrX_+_68693629 2.98 ENST00000374597.3
StAR related lipid transfer domain containing 8
chr15_-_77420087 2.96 ENST00000564328.5
ENST00000682557.1
ENST00000558305.5
pseudopodium enriched atypical kinase 1
chr15_+_81296913 2.95 ENST00000394652.6
interleukin 16
chr14_+_73950489 2.95 ENST00000554320.1
coenzyme Q6, monooxygenase
chr12_-_25195074 2.95 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
cilia and flagella associated protein 94
chr11_+_5689780 2.94 ENST00000379965.8
ENST00000454828.5
tripartite motif containing 22
chr2_-_27663817 2.93 ENST00000404798.6
SPT7 like, STAGA complex subunit gamma
chr18_+_616672 2.92 ENST00000338387.11
clusterin like 1
chr12_+_101594849 2.92 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr2_-_88947820 2.91 ENST00000496168.1
immunoglobulin kappa variable 1-5
chrX_+_154304923 2.91 ENST00000426989.5
ENST00000426203.5
ENST00000369912.2
transketolase like 1
chr11_-_62754141 2.91 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
zinc finger and BTB domain containing 3
chr19_+_35748549 2.91 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr2_-_88861258 2.87 ENST00000390240.2
immunoglobulin kappa joining 3
chr3_-_161105070 2.80 ENST00000651430.1
ENST00000650695.1
ENST00000651689.1
ENST00000651916.1
ENST00000488170.5
ENST00000652377.1
ENST00000652669.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_174700413 2.77 ENST00000529145.6
ENST00000325589.9
RAB GTPase activating protein 1 like
chr13_-_19181773 2.76 ENST00000618094.1
ENST00000400113.8
tubulin alpha 3c
chr1_+_207053229 2.76 ENST00000367080.8
ENST00000367079.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr20_-_52105644 2.75 ENST00000371523.8
ZFP64 zinc finger protein
chr14_+_103715724 2.73 ENST00000216602.10
zinc finger FYVE-type containing 21
chr3_-_161105399 2.68 ENST00000652593.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr6_+_63635792 2.66 ENST00000262043.8
ENST00000506783.5
ENST00000481385.6
ENST00000515594.5
ENST00000494284.6
PHD finger protein 3
chr3_-_167474026 2.64 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr1_+_27392612 2.64 ENST00000374024.4
G protein-coupled receptor 3
chr4_+_118888829 2.64 ENST00000448416.6
ENST00000307142.9
ENST00000429713.7
synaptopodin 2
chr1_+_171185293 2.64 ENST00000209929.10
flavin containing dimethylaniline monoxygenase 2
chrX_+_1591590 2.62 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr19_-_14848922 2.59 ENST00000641129.1
olfactory receptor family 7 subfamily A member 10
chr2_+_90220727 2.58 ENST00000471857.2
immunoglobulin kappa variable 1D-8
chr3_+_184186023 2.57 ENST00000429586.6
ENST00000292808.5
ATP binding cassette subfamily F member 3
chr20_+_45416551 2.57 ENST00000639292.1
phosphatidylinositol glycan anchor biosynthesis class T
chr1_+_151766655 2.54 ENST00000400999.7
ornithine decarboxylase antizyme 3
chr1_+_12857086 2.53 ENST00000240189.2
PRAME family member 2
chr14_+_32329341 2.52 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr10_+_46375619 2.52 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr5_-_22853320 2.51 ENST00000504376.6
ENST00000382254.6
cadherin 12
chr14_+_32329256 2.51 ENST00000280979.9
A-kinase anchoring protein 6
chr1_-_13116854 2.49 ENST00000621994.3
heterogeneous nuclear ribonucleoprotein C like 2
chr2_+_102337148 2.48 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chrX_+_83861126 2.44 ENST00000621735.4
ENST00000329312.5
cylicin 1
chr16_+_3283443 2.44 ENST00000572748.1
ENST00000219069.6
ENST00000573578.1
ENST00000574253.1
zinc finger protein 263
chr6_+_110180418 2.44 ENST00000368930.5
ENST00000307731.2
cell division cycle 40
chr19_+_57633161 2.43 ENST00000541801.5
ENST00000347302.7
ENST00000240731.5
ENST00000254182.11
ENST00000391703.3
zinc finger protein 211
chr17_+_75456618 2.42 ENST00000314256.12
ENST00000582186.5
ENST00000582455.5
ENST00000581252.5
ENST00000579208.5
transmembrane protein 94
chr5_+_55102635 2.38 ENST00000274306.7
granzyme A
chr2_-_240557957 2.38 ENST00000373318.6
ENST00000406958.5
ENST00000272972.7
ENST00000401804.5
ENST00000361678.8
ENST00000391987.5
ENST00000405523.7
ankyrin repeat and MYND domain containing 1
chr17_+_82458174 2.37 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
nuclear prelamin A recognition factor
chr9_-_96778053 2.35 ENST00000375231.5
ENST00000223428.9
zinc finger protein 510
chr9_-_92878018 2.35 ENST00000332591.6
ENST00000375495.8
ENST00000395505.6
ENST00000395506.7
zinc finger protein 484
chr10_+_46375645 2.33 ENST00000622769.4
annexin A8 like 1
chr9_+_34652167 2.31 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr8_+_104223320 2.31 ENST00000339750.3
regulating synaptic membrane exocytosis 2
chr10_+_92691813 2.29 ENST00000472590.6
hematopoietically expressed homeobox
chr1_-_12947580 2.25 ENST00000376189.5
PRAME family member 6
chr4_-_48080172 2.25 ENST00000507351.1
TXK tyrosine kinase
chrX_-_154097668 2.25 ENST00000407218.5
ENST00000303391.11
ENST00000453960.7
methyl-CpG binding protein 2
chr6_+_160121859 2.25 ENST00000324965.8
ENST00000457470.6
solute carrier family 22 member 1
chr10_-_99620401 2.25 ENST00000370495.6
solute carrier family 25 member 28
chr12_+_8123609 2.19 ENST00000229332.12
C-type lectin domain family 4 member A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 22.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
4.7 23.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
4.6 27.5 GO:0046092 deoxycytidine metabolic process(GO:0046092)
3.0 9.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.9 20.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
2.6 7.8 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
2.6 7.8 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.0 6.1 GO:0034769 basement membrane disassembly(GO:0034769)
2.0 25.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.8 5.5 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
1.7 5.0 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.6 8.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
1.6 6.2 GO:0035627 ceramide transport(GO:0035627)
1.5 4.6 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.5 4.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.3 5.0 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
1.2 4.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
1.2 3.5 GO:1904742 protein auto-ADP-ribosylation(GO:0070213) regulation of telomeric DNA binding(GO:1904742)
1.1 4.4 GO:1904823 pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
1.1 3.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.0 6.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
1.0 2.9 GO:0061011 hepatic duct development(GO:0061011)
0.9 3.7 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.9 11.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.8 2.5 GO:0015847 putrescine transport(GO:0015847)
0.8 5.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.8 5.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.8 11.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.8 3.2 GO:0099558 maintenance of synapse structure(GO:0099558)
0.8 4.7 GO:0071896 protein localization to adherens junction(GO:0071896)
0.7 2.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.7 3.0 GO:1904383 response to sodium phosphate(GO:1904383)
0.7 2.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.6 1.3 GO:0009822 alkaloid catabolic process(GO:0009822)
0.6 1.9 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.6 3.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.6 4.4 GO:0048241 epinephrine transport(GO:0048241)
0.6 5.0 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.6 1.8 GO:1904432 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.6 9.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.6 2.9 GO:0006772 thiamine metabolic process(GO:0006772)
0.6 19.1 GO:0071711 basement membrane organization(GO:0071711)
0.6 1.7 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.6 2.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.6 1.7 GO:1903487 regulation of lactation(GO:1903487)
0.6 11.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.5 1.6 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.5 8.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.5 1.6 GO:0002668 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.5 3.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 2.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.5 1.5 GO:0070055 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.5 3.5 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.5 2.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.5 14.3 GO:0072643 interferon-gamma secretion(GO:0072643)
0.5 6.6 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.5 2.3 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.5 10.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.5 2.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.5 4.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) positive regulation of viral entry into host cell(GO:0046598)
0.5 4.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.4 4.0 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.4 9.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.4 3.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.4 0.8 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.4 1.2 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.4 8.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 4.4 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.4 2.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.4 1.2 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.4 0.4 GO:0048769 sarcomerogenesis(GO:0048769)
0.4 0.7 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
0.3 2.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 13.3 GO:0019430 removal of superoxide radicals(GO:0019430)
0.3 13.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 60.4 GO:0002377 immunoglobulin production(GO:0002377)
0.3 2.6 GO:0070995 NADPH oxidation(GO:0070995)
0.3 2.0 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 7.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.3 0.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.3 2.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 3.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 7.1 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.3 4.6 GO:0016180 snRNA processing(GO:0016180)
0.3 0.3 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.3 8.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.3 1.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.3 1.7 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.3 3.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 3.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.3 0.8 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.3 4.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 1.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.3 2.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.3 0.8 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.2 1.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.7 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 1.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 6.4 GO:0044458 motile cilium assembly(GO:0044458)
0.2 1.4 GO:0050955 thermoception(GO:0050955)
0.2 0.9 GO:0045658 negative regulation of interleukin-6 biosynthetic process(GO:0045409) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 6.7 GO:0036314 response to sterol(GO:0036314)
0.2 0.9 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 1.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903) regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.2 2.5 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 2.8 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.2 3.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 2.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.2 6.8 GO:0019835 cytolysis(GO:0019835)
0.2 3.5 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 1.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 2.8 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 2.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 6.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.2 1.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 5.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 0.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 5.1 GO:0045730 respiratory burst(GO:0045730)
0.2 0.5 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.2 3.5 GO:0050892 intestinal absorption(GO:0050892)
0.2 3.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.8 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 2.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.6 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 1.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 1.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.7 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 4.4 GO:0030220 platelet formation(GO:0030220)
0.1 1.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 11.8 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.9 GO:0009642 response to light intensity(GO:0009642)
0.1 3.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.7 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 3.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.8 GO:0048840 otolith development(GO:0048840)
0.1 2.2 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.9 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 4.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.6 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 3.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 10.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 3.5 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.1 5.8 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 0.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 1.1 GO:0006552 leucine catabolic process(GO:0006552)
0.1 2.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.5 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 3.2 GO:0010107 potassium ion import(GO:0010107)
0.1 1.6 GO:0030728 ovulation(GO:0030728)
0.1 1.0 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 0.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 5.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 33.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.6 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.4 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.1 1.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 6.7 GO:0030449 regulation of complement activation(GO:0030449)
0.1 4.3 GO:0002456 T cell mediated immunity(GO:0002456)
0.1 1.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 3.3 GO:0070206 protein trimerization(GO:0070206)
0.1 6.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 4.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.2 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 1.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 1.2 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 2.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.6 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 6.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 2.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 2.0 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 4.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 4.9 GO:0007272 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0 0.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 2.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 1.0 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 2.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.6 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 4.7 GO:0002250 adaptive immune response(GO:0002250)
0.0 1.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 3.3 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 1.6 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.6 GO:0007416 synapse assembly(GO:0007416)
0.0 1.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.9 GO:0030324 lung development(GO:0030324)
0.0 1.5 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.6 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
2.1 6.4 GO:0097224 sperm connecting piece(GO:0097224)
2.0 25.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.4 4.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
1.4 8.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.2 8.5 GO:0060091 kinocilium(GO:0060091)
1.1 11.9 GO:0043203 axon hillock(GO:0043203)
1.0 13.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.0 8.2 GO:0005579 membrane attack complex(GO:0005579)
1.0 11.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.9 2.7 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.9 6.1 GO:0036021 endolysosome lumen(GO:0036021)
0.8 5.0 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.8 2.4 GO:0043159 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.8 4.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.7 11.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.7 3.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.7 2.8 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.7 10.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.7 8.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.6 2.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.6 5.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.6 4.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.5 3.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.5 3.7 GO:0070187 telosome(GO:0070187)
0.5 1.4 GO:0005588 collagen type V trimer(GO:0005588)
0.4 16.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.4 4.6 GO:0032039 integrator complex(GO:0032039)
0.4 1.6 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.4 5.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.4 1.8 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.4 3.2 GO:0097452 GAIT complex(GO:0097452)
0.3 3.7 GO:0005638 lamin filament(GO:0005638)
0.3 8.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.3 3.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 1.8 GO:1990635 proximal dendrite(GO:1990635)
0.3 3.8 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 3.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 7.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 5.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 4.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.6 GO:1990130 Iml1 complex(GO:1990130)
0.2 3.4 GO:0030914 STAGA complex(GO:0030914)
0.2 2.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.2 3.5 GO:0000242 pericentriolar material(GO:0000242)
0.2 22.0 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.7 GO:0042825 TAP complex(GO:0042825)
0.1 2.5 GO:0033270 paranode region of axon(GO:0033270)
0.1 14.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 2.9 GO:0032982 myosin filament(GO:0032982)
0.1 1.9 GO:0036038 MKS complex(GO:0036038)
0.1 11.2 GO:0005604 basement membrane(GO:0005604)
0.1 3.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 3.1 GO:0034451 centriolar satellite(GO:0034451)
0.1 6.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 8.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 14.5 GO:0032993 protein-DNA complex(GO:0032993)
0.1 4.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 3.3 GO:0001772 immunological synapse(GO:0001772)
0.1 1.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.2 GO:0036019 endolysosome(GO:0036019)
0.1 11.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 83.5 GO:0005615 extracellular space(GO:0005615)
0.1 8.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 6.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 1.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 8.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 2.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 9.6 GO:0005774 vacuolar membrane(GO:0005774)
0.0 1.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 3.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 15.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 2.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 20.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.9 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 22.1 GO:0019770 IgG receptor activity(GO:0019770)
3.9 27.5 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
3.0 18.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
2.0 9.9 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
1.6 6.2 GO:0097001 ceramide binding(GO:0097001)
1.5 4.4 GO:0015265 urea channel activity(GO:0015265)
1.3 8.0 GO:0008142 oxysterol binding(GO:0008142)
1.1 3.4 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
1.1 4.4 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.0 3.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
1.0 5.9 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.9 4.4 GO:0047374 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.9 12.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.8 2.5 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.8 5.9 GO:0030492 hemoglobin binding(GO:0030492)
0.8 2.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.8 4.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.8 8.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.8 3.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.7 3.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 2.9 GO:0004802 transketolase activity(GO:0004802)
0.7 4.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.7 5.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.7 2.8 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.7 2.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.7 2.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.6 6.4 GO:0032027 myosin light chain binding(GO:0032027)
0.6 2.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.6 1.9 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.6 5.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.6 1.9 GO:1902271 D3 vitamins binding(GO:1902271)
0.6 5.5 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.6 1.8 GO:0070052 collagen V binding(GO:0070052)
0.6 3.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.6 6.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 1.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.5 4.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.5 2.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.4 5.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.4 7.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.4 1.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.4 5.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 49.8 GO:0005518 collagen binding(GO:0005518)
0.4 11.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 3.2 GO:1990405 protein antigen binding(GO:1990405)
0.4 1.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.4 8.2 GO:0043495 protein anchor(GO:0043495)
0.4 2.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 23.5 GO:0015485 cholesterol binding(GO:0015485)
0.4 3.6 GO:0001851 complement component C3b binding(GO:0001851)
0.4 5.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 4.9 GO:0031419 cobalamin binding(GO:0031419)
0.3 7.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.3 6.6 GO:0035497 cAMP response element binding(GO:0035497)
0.3 12.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 33.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 5.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 4.6 GO:0015643 toxic substance binding(GO:0015643)
0.3 13.6 GO:0004532 exoribonuclease activity(GO:0004532)
0.3 0.9 GO:0005502 11-cis retinal binding(GO:0005502)
0.3 3.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 0.8 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.2 0.7 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 0.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.7 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.2 5.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.9 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.2 2.3 GO:0004064 arylesterase activity(GO:0004064)
0.2 0.9 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 1.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 45.4 GO:0003823 antigen binding(GO:0003823)
0.2 12.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 2.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 1.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 3.3 GO:0070330 aromatase activity(GO:0070330)
0.2 3.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 2.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 1.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 3.7 GO:0005521 lamin binding(GO:0005521)
0.2 14.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 0.7 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 2.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.7 GO:0019864 IgG binding(GO:0019864)
0.1 1.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.6 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 1.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 10.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.8 GO:0031489 myosin V binding(GO:0031489)
0.1 0.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 3.0 GO:0071949 FAD binding(GO:0071949)
0.1 1.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 37.0 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 20.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 4.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 1.8 GO:0070402 NADPH binding(GO:0070402)
0.1 0.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.6 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 3.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 3.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 6.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 10.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.6 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 4.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 3.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 12.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 4.7 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 3.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 4.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 2.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 11.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 1.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 9.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 1.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 1.3 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 7.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 2.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 2.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 12.2 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 23.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 21.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 16.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.3 8.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 16.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 60.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 12.7 PID CD40 PATHWAY CD40/CD40L signaling
0.2 4.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 7.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 9.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 8.4 PID BMP PATHWAY BMP receptor signaling
0.1 8.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 2.5 PID ARF 3PATHWAY Arf1 pathway
0.1 1.0 PID IL27 PATHWAY IL27-mediated signaling events
0.1 15.6 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 1.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 3.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 4.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 9.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 4.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.3 PID MYC PATHWAY C-MYC pathway
0.1 2.4 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 10.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 7.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 3.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 13.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.9 25.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.6 6.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 9.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.5 11.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.5 11.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.5 3.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.4 6.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 9.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 8.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.3 4.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 3.4 REACTOME OPSINS Genes involved in Opsins
0.3 2.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 7.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3 12.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 3.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 2.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 11.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 3.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 9.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 9.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 3.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 7.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 4.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 1.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 5.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 6.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 29.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 8.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 2.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 3.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 4.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 3.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 6.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 2.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 2.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 5.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 22.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 2.0 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 2.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX Genes involved in Signaling by TGF-beta Receptor Complex
0.0 1.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.5 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA