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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for POU2F2_POU3F1

Z-value: 2.64

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
ENSG00000028277.21 POU2F2
ENSG00000185668.8 POU3F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg38_v1_chr19_-_42132391_421324550.484.7e-14Click!
POU3F1hg38_v1_chr1_-_38046785_380468020.276.0e-05Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_106117159 113.84 ENST00000390601.3
immunoglobulin heavy variable 3-11
chr14_-_106470788 105.15 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr14_-_106538331 97.59 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr2_+_90209873 93.23 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr16_+_33802683 92.90 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr2_-_89040745 92.79 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr2_-_88992903 85.33 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr2_+_90100235 79.14 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr16_+_32066065 75.00 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr2_+_90082635 73.73 ENST00000483379.1
immunoglobulin kappa variable 1D-17
chr2_+_90159840 71.55 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr14_-_106235582 70.35 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr14_-_106675544 70.28 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr14_-_106088573 65.19 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr16_+_33009175 62.38 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr14_-_106658251 61.13 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr2_+_89884740 57.45 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr1_-_149842736 56.63 ENST00000369159.2
H2A clustered histone 18
chr16_-_33845229 56.56 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr2_+_89913982 55.96 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr1_+_149851053 54.93 ENST00000607355.2
H2A clustered histone 19
chr21_-_10649835 54.07 ENST00000622028.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr2_-_89297785 51.02 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr14_-_106715166 50.42 ENST00000390633.2
immunoglobulin heavy variable 1-69
chr14_-_106593319 50.18 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr2_-_89100352 49.38 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr2_+_90154073 47.45 ENST00000611391.1
immunoglobulin kappa variable 1D-13
chr22_+_22357739 45.96 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr14_-_106811131 45.84 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr15_-_19988117 45.66 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_+_90021567 45.42 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr2_-_89268506 45.22 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr14_-_106062670 44.47 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr2_+_90069662 43.87 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_+_90038848 43.78 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr14_-_106389858 41.90 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr6_+_27147094 41.79 ENST00000377459.3
H2A clustered histone 12
chr14_-_106154113 41.29 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr22_+_22822658 38.21 ENST00000620395.2
immunoglobulin lambda variable 2-8
chr16_+_32995048 38.11 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr22_+_22734577 37.24 ENST00000390310.3
immunoglobulin lambda variable 2-18
chr2_+_90234809 37.11 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr22_+_22811737 37.10 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr1_+_149886906 35.36 ENST00000331380.4
H2A clustered histone 20
chr2_-_88979016 34.82 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr2_-_89117844 34.37 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr14_-_106269133 33.76 ENST00000390609.3
immunoglobulin heavy variable 3-23
chr14_-_106211453 33.08 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr11_-_5227063 32.47 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr22_+_22431949 32.36 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr17_+_20155989 31.73 ENST00000395530.6
ENST00000581399.6
ENST00000679819.1
sperm antigen with calponin homology and coiled-coil domains 1
chr1_-_149886652 31.58 ENST00000369155.3
H2B clustered histone 21
chr2_-_89160329 31.34 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr2_+_90172802 31.33 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr6_+_26124161 31.19 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr14_-_106025628 31.17 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr2_+_89862438 31.03 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr14_-_106165730 30.73 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr8_+_55879818 30.33 ENST00000520220.6
ENST00000519728.6
LYN proto-oncogene, Src family tyrosine kinase
chr2_-_88966767 30.28 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr22_+_22758698 30.06 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr6_+_37170133 29.75 ENST00000373509.6
Pim-1 proto-oncogene, serine/threonine kinase
chr14_-_106557465 29.22 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr14_-_106507476 29.06 ENST00000390621.3
immunoglobulin heavy variable 1-45
chr16_+_23835946 27.95 ENST00000321728.12
ENST00000643927.1
protein kinase C beta
chr2_+_113406368 27.94 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr22_+_22697789 27.89 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr4_-_70666492 27.80 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr8_-_133102477 26.72 ENST00000522119.5
ENST00000523610.5
ENST00000338087.10
ENST00000521302.5
ENST00000519558.5
ENST00000519747.5
ENST00000517648.5
Src like adaptor
chrX_-_107717054 26.37 ENST00000503515.1
ENST00000372397.6
TSC22 domain family member 3
chr17_-_49764123 25.46 ENST00000240364.7
ENST00000506156.1
family with sequence similarity 117 member A
chr16_+_33827140 25.09 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr8_-_133102874 25.00 ENST00000395352.7
Src like adaptor
chr14_-_106762576 24.80 ENST00000624687.1
immunoglobulin heavy variable 1-69D
chr14_-_106360320 24.01 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr2_-_89245596 23.87 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr14_-_106277039 23.86 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr2_-_89320146 23.77 ENST00000498574.1
immunoglobulin kappa variable 1-39
chr14_-_106335613 23.60 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr1_-_149812359 23.57 ENST00000369167.2
ENST00000545683.1
H2B clustered histone 18
chr1_+_228458095 23.47 ENST00000620438.1
H2B.U histone 1
chr22_+_22588155 23.26 ENST00000390302.3
immunoglobulin lambda variable 2-33 (non-functional)
chr2_-_88947820 22.60 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr2_+_90114838 22.45 ENST00000417279.3
immunoglobulin kappa variable 3D-15
chr7_-_100586119 21.88 ENST00000310300.11
leucine rich repeats and calponin homology domain containing 4
chr2_+_89851723 20.31 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr2_+_89936859 20.03 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr22_+_22747383 19.61 ENST00000390311.3
immunoglobulin lambda variable 3-16
chr22_+_22818994 19.49 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr15_-_19965101 19.32 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr22_+_22686724 18.64 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr6_-_27146841 18.10 ENST00000356950.2
H2B clustered histone 12
chr14_-_106875069 17.08 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr14_-_106374129 16.71 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr14_-_106130061 16.18 ENST00000390602.3
immunoglobulin heavy variable 3-13
chr1_+_156150008 14.96 ENST00000355014.6
semaphorin 4A
chrX_-_107775951 14.91 ENST00000315660.8
ENST00000372384.6
ENST00000502650.1
ENST00000506724.1
TSC22 domain family member 3
chr6_-_26216673 14.70 ENST00000541790.3
H2B clustered histone 8
chr14_-_106737547 14.44 ENST00000632209.1
immunoglobulin heavy variable 1-69-2
chrX_+_12975083 13.08 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr19_-_17405554 13.05 ENST00000252593.7
bone marrow stromal cell antigen 2
chr4_-_25863537 12.84 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr10_-_96271508 12.60 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr1_+_116754422 12.39 ENST00000369478.4
ENST00000369477.1
CD2 molecule
chr22_+_22704265 12.04 ENST00000390307.2
immunoglobulin lambda variable 3-22
chr6_-_27814757 11.88 ENST00000333151.5
H2A clustered histone 14
chr22_+_22720615 11.44 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr19_-_18281612 11.28 ENST00000252818.5
JunD proto-oncogene, AP-1 transcription factor subunit
chr1_+_207325629 11.02 ENST00000618707.2
CD55 molecule (Cromer blood group)
chr6_+_26158115 10.60 ENST00000377777.5
ENST00000289316.2
H2B clustered histone 5
chr9_+_133459965 10.46 ENST00000540581.5
ENST00000542192.5
ENST00000291722.11
ENST00000316948.9
calcium channel flower domain containing 1
chr3_-_18425295 9.98 ENST00000338745.11
ENST00000450898.1
SATB homeobox 1
chr19_+_19033575 9.90 ENST00000392335.6
ENST00000537263.5
ENST00000540707.5
ENST00000535612.6
ENST00000541725.5
ENST00000269932.10
ENST00000546344.5
ENST00000540792.5
ENST00000536098.5
ENST00000541898.5
armadillo repeat containing 6
chr12_-_7092422 9.89 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr6_+_27815010 9.83 ENST00000621112.2
H2B clustered histone 14
chrX_-_48919015 9.53 ENST00000376509.4
Pim-2 proto-oncogene, serine/threonine kinase
chr6_-_27807916 9.30 ENST00000377401.3
H2B clustered histone 13
chr4_+_40192949 9.20 ENST00000507851.5
ENST00000615577.4
ENST00000613272.4
ras homolog family member H
chr6_+_27808163 9.19 ENST00000358739.4
H2A clustered histone 13
chr17_-_19748341 9.16 ENST00000395555.7
aldehyde dehydrogenase 3 family member A1
chr21_+_38272410 8.90 ENST00000398934.5
ENST00000398930.5
potassium inwardly rectifying channel subfamily J member 15
chr22_-_23754376 8.80 ENST00000398465.3
ENST00000248948.4
V-set pre-B cell surrogate light chain 3
chr6_-_81752671 8.75 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr11_-_130002818 8.66 ENST00000358825.9
ENST00000360871.8
ENST00000528746.5
PR/SET domain 10
chr17_-_19748285 8.66 ENST00000570414.1
ENST00000225740.11
aldehyde dehydrogenase 3 family member A1
chr18_-_55321986 8.41 ENST00000570287.6
transcription factor 4
chr6_+_27865308 8.32 ENST00000613174.2
H2A clustered histone 16
chr16_+_28931942 8.22 ENST00000324662.8
ENST00000538922.8
CD19 molecule
chr17_-_19748355 8.19 ENST00000494157.6
aldehyde dehydrogenase 3 family member A1
chr16_+_56935371 8.03 ENST00000568358.1
homocysteine inducible ER protein with ubiquitin like domain 1
chr18_-_55322215 8.03 ENST00000457482.7
transcription factor 4
chr19_+_54617122 7.43 ENST00000396331.5
leukocyte immunoglobulin like receptor B1
chr12_-_7503744 7.27 ENST00000396620.7
ENST00000432237.3
CD163 molecule
chr6_-_34146080 7.09 ENST00000538487.7
ENST00000374181.8
glutamate metabotropic receptor 4
chr19_+_17747698 7.03 ENST00000594202.5
ENST00000252771.11
FCH and mu domain containing endocytic adaptor 1
chr6_-_35688907 6.98 ENST00000539068.5
ENST00000357266.9
FKBP prolyl isomerase 5
chr22_+_22409755 6.97 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr18_-_55422492 6.88 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr9_-_124771304 6.84 ENST00000416460.6
ENST00000487099.7
nuclear receptor subfamily 6 group A member 1
chr6_-_27132750 6.69 ENST00000607124.1
ENST00000339812.3
H2B clustered histone 11
chr19_+_35329161 6.64 ENST00000341773.10
ENST00000600131.5
ENST00000595780.5
ENST00000597916.5
ENST00000593867.5
ENST00000600424.5
ENST00000599811.5
ENST00000536635.6
ENST00000085219.10
ENST00000544992.6
ENST00000419549.6
CD22 molecule
chr6_+_26216928 6.58 ENST00000303910.4
H2A clustered histone 8
chr22_+_22030934 6.42 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr19_-_40285277 6.37 ENST00000579047.5
ENST00000392038.7
AKT serine/threonine kinase 2
chr6_+_27893411 6.36 ENST00000616182.2
H2B clustered histone 17
chrX_+_12975216 6.15 ENST00000380635.5
thymosin beta 4 X-linked
chr17_+_75525682 6.09 ENST00000392550.8
ENST00000167462.9
ENST00000375227.8
ENST00000578363.5
ENST00000579392.5
LLGL scribble cell polarity complex component 2
chr19_-_1021114 6.08 ENST00000333175.9
ENST00000356663.8
transmembrane protein 259
chr4_-_40515967 6.08 ENST00000381795.10
RNA binding motif protein 47
chr14_-_106005574 6.04 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr9_-_81688354 5.75 ENST00000418319.5
TLE family member 1, transcriptional corepressor
chr2_-_174598206 5.73 ENST00000392546.6
ENST00000436221.1
WAS/WASL interacting protein family member 1
chr7_+_27242796 5.71 ENST00000496902.7
even-skipped homeobox 1
chr1_+_103655760 5.57 ENST00000370083.9
amylase alpha 1A
chr11_-_2885728 5.49 ENST00000647251.1
ENST00000380725.2
ENST00000430149.3
ENST00000414822.8
ENST00000440480.8
cyclin dependent kinase inhibitor 1C
chr4_-_18021727 5.42 ENST00000675605.1
ENST00000675927.1
ENST00000674942.1
ENST00000675143.1
ENST00000382226.5
ENST00000326877.8
ENST00000635767.1
ligand dependent nuclear receptor corepressor like
chr11_-_62591500 5.35 ENST00000476907.6
ENST00000278279.7
terminal uridylyl transferase 1, U6 snRNA-specific
chr12_-_10723307 5.24 ENST00000279550.11
ENST00000228251.9
Y-box binding protein 3
chr7_-_130440848 5.24 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
centrosomal protein 41
chr1_+_66332004 5.21 ENST00000371045.9
ENST00000531025.5
ENST00000526197.5
phosphodiesterase 4B
chr7_+_16753731 5.20 ENST00000262067.5
tetraspanin 13
chr12_+_62260338 5.03 ENST00000353364.7
ENST00000549523.5
ubiquitin specific peptidase 15
chr8_+_19939246 5.00 ENST00000650287.1
lipoprotein lipase
chrX_-_130903224 4.97 ENST00000370935.5
ecto-NOX disulfide-thiol exchanger 2
chr11_-_62601818 4.93 ENST00000278823.7
metastasis associated 1 family member 2
chr19_-_49665603 4.90 ENST00000596756.5
interferon regulatory factor 3
chr17_+_40341388 4.73 ENST00000394086.7
retinoic acid receptor alpha
chr4_+_123399488 4.72 ENST00000394339.2
sprouty RTK signaling antagonist 1
chr18_-_55585773 4.70 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr2_-_218002988 4.65 ENST00000682258.1
ENST00000446903.5
tensin 1
chr10_-_96271553 4.59 ENST00000224337.10
B cell linker
chr9_+_89605004 4.56 ENST00000252506.11
ENST00000375769.1
growth arrest and DNA damage inducible gamma
chr6_-_11232658 4.48 ENST00000379433.5
ENST00000379446.10
ENST00000620854.4
neural precursor cell expressed, developmentally down-regulated 9
chr19_+_17747737 4.39 ENST00000600676.5
ENST00000600209.5
ENST00000596309.5
ENST00000598539.5
ENST00000597474.5
ENST00000593385.5
ENST00000598067.5
ENST00000593833.5
FCH and mu domain containing endocytic adaptor 1
chr11_-_62591554 4.38 ENST00000494385.1
ENST00000308436.11
terminal uridylyl transferase 1, U6 snRNA-specific
chr17_-_7929793 4.37 ENST00000303790.3
potassium voltage-gated channel subfamily A regulatory beta subunit 3
chr18_-_55423757 4.37 ENST00000675707.1
transcription factor 4
chr19_+_35371290 4.35 ENST00000597214.1
G protein-coupled receptor 42
chr17_-_75779758 4.33 ENST00000592643.5
ENST00000591890.5
ENST00000587171.1
ENST00000254810.8
ENST00000589599.5
H3.3 histone B
chr6_+_26272923 4.31 ENST00000377733.4
H2B clustered histone 10
chr19_-_40285395 4.30 ENST00000424901.5
ENST00000578123.5
AKT serine/threonine kinase 2
chr8_-_56211257 4.28 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1 zinc finger
chr12_-_7503841 4.26 ENST00000359156.8
CD163 molecule
chr12_+_62260374 4.26 ENST00000312635.10
ENST00000280377.10
ENST00000549237.5
ubiquitin specific peptidase 15
chr7_-_73624492 4.17 ENST00000414749.6
ENST00000429400.6
ENST00000434326.5
ENST00000313375.8
ENST00000354613.5
ENST00000453275.1
MLX interacting protein like
chr7_+_80646436 4.16 ENST00000419819.2
CD36 molecule
chr6_-_53148822 4.05 ENST00000259803.8
glial cells missing transcription factor 1
chrX_-_130903187 4.04 ENST00000432489.5
ENST00000394363.6
ENST00000338144.8
ecto-NOX disulfide-thiol exchanger 2
chr7_+_100586304 4.00 ENST00000241071.11
F-box protein 24
chr1_+_207496147 3.94 ENST00000400960.7
ENST00000367049.9
complement C3b/C4b receptor 1 (Knops blood group)
chrX_+_100584928 3.84 ENST00000373031.5
tenomodulin
chr5_-_67196791 3.78 ENST00000256447.5
CD180 molecule
chr4_+_93828746 3.78 ENST00000306011.6
atonal bHLH transcription factor 1
chr5_-_65481907 3.74 ENST00000381055.8
ADAM metallopeptidase with thrombospondin type 1 motif 6
chr4_-_99321362 3.72 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chrX_-_102380093 3.65 ENST00000604395.5
nuclear RNA export factor 2B
chr22_-_42614871 3.51 ENST00000252115.10
DNA polymerase delta interacting protein 3
chr10_-_114144599 3.44 ENST00000428953.1
coiled-coil domain containing 186
chr7_+_50308672 3.32 ENST00000439701.2
ENST00000438033.5
ENST00000492782.6
IKAROS family zinc finger 1
chr17_+_45135640 3.29 ENST00000586346.5
ENST00000321854.13
ENST00000398322.7
ENST00000592162.5
ENST00000376955.8
acyl-CoA binding domain containing 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
15.4 2277.5 GO:0006958 complement activation, classical pathway(GO:0006958)
11.7 58.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
10.8 32.5 GO:0030185 nitric oxide transport(GO:0030185)
5.2 41.3 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
4.4 13.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
4.2 739.4 GO:0002377 immunoglobulin production(GO:0002377)
4.0 27.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
3.6 10.7 GO:0097473 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
2.5 7.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
2.5 29.7 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
2.4 19.2 GO:2000483 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) negative regulation of interleukin-8 secretion(GO:2000483)
2.1 12.4 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
1.9 7.4 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
1.4 4.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.3 4.0 GO:0060018 astrocyte fate commitment(GO:0060018)
1.3 24.0 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
1.3 2.6 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
1.2 4.7 GO:0060010 Sertoli cell fate commitment(GO:0060010)
1.2 4.7 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.2 7.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.1 10.6 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
1.0 6.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.9 9.7 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.8 2.5 GO:0060435 bronchiole development(GO:0060435)
0.8 2.5 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.8 10.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.8 3.8 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.8 3.8 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.7 5.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.7 6.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.7 2.1 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.7 16.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.7 5.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.6 3.8 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.6 8.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.6 2.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.6 14.1 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.5 2.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.5 1.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.5 51.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.5 2.6 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.5 5.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.5 1.5 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.5 2.7 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.4 5.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 7.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4 11.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 5.8 GO:2000811 negative regulation of anoikis(GO:2000811)
0.4 1.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.4 1.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.3 3.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 2.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 4.2 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.3 2.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 4.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.3 6.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.3 5.8 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 77.4 GO:0002250 adaptive immune response(GO:0002250)
0.2 8.2 GO:0030449 regulation of complement activation(GO:0030449)
0.2 35.4 GO:0051591 response to cAMP(GO:0051591)
0.2 1.0 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.2 1.5 GO:0070995 NADPH oxidation(GO:0070995)
0.2 3.3 GO:0031033 myosin filament organization(GO:0031033)
0.2 9.6 GO:0010761 fibroblast migration(GO:0010761)
0.1 7.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 3.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 6.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 8.2 GO:0006953 acute-phase response(GO:0006953)
0.1 9.5 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.1 1.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 2.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 4.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.2 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.5 GO:0043697 forebrain anterior/posterior pattern specification(GO:0021797) dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 1.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 1.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 1.8 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 4.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 2.4 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 1.4 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 1.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.8 GO:0016180 snRNA processing(GO:0016180)
0.0 3.7 GO:0003279 cardiac septum development(GO:0003279)
0.0 5.2 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 3.6 GO:0006959 humoral immune response(GO:0006959)
0.0 3.4 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.7 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.7 GO:0032570 response to progesterone(GO:0032570)
0.0 0.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.6 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.2 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 2.0 GO:0002576 platelet degranulation(GO:0002576)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
19.7 1045.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
8.1 32.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
6.1 30.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
2.2 395.9 GO:0072562 blood microparticle(GO:0072562)
1.4 11.3 GO:0035976 AP1 complex(GO:0035976)
1.1 8.0 GO:1990037 Lewy body core(GO:1990037)
1.0 1.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.9 2.6 GO:0043293 apoptosome(GO:0043293)
0.7 19.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.6 9.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.6 949.0 GO:0005615 extracellular space(GO:0005615)
0.5 1.6 GO:0005927 muscle tendon junction(GO:0005927)
0.4 12.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 6.5 GO:0000346 transcription export complex(GO:0000346)
0.4 1.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3 13.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.3 1.5 GO:1990031 pinceau fiber(GO:1990031)
0.3 1.8 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 5.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 24.1 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 19.0 GO:0016605 PML body(GO:0016605)
0.1 29.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 4.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 25.8 GO:0032993 protein-DNA complex(GO:0032993)
0.1 7.4 GO:0001772 immunological synapse(GO:0001772)
0.1 25.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 11.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 7.9 GO:0005884 actin filament(GO:0005884)
0.1 10.7 GO:0032587 ruffle membrane(GO:0032587)
0.1 5.2 GO:0005844 polysome(GO:0005844)
0.1 374.3 GO:0005576 extracellular region(GO:0005576)
0.1 0.8 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 4.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.1 GO:0005901 caveola(GO:0005901)
0.0 2.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 4.9 GO:0005938 cell cortex(GO:0005938)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 4.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 2.2 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
17.4 1045.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
10.2 1903.6 GO:0003823 antigen binding(GO:0003823)
7.0 28.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
5.9 29.4 GO:0043208 glycosphingolipid binding(GO:0043208)
4.6 32.5 GO:0030492 hemoglobin binding(GO:0030492)
4.6 41.3 GO:0043426 MRF binding(GO:0043426)
2.9 8.6 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
2.0 32.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.9 29.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.9 9.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.9 7.4 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
1.9 5.6 GO:0004556 alpha-amylase activity(GO:0004556)
1.7 5.0 GO:0017129 triglyceride binding(GO:0017129)
1.5 32.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.4 9.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.0 17.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.0 3.0 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.8 2.5 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.8 11.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.7 2.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.7 5.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.7 2.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.7 12.6 GO:0038191 neuropilin binding(GO:0038191)
0.6 5.8 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.6 13.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 4.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.6 51.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.6 1.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.5 4.2 GO:0030274 LIM domain binding(GO:0030274)
0.5 3.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.5 8.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 13.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.4 4.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 1.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.3 1.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 7.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 5.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 9.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.3 5.7 GO:0005522 profilin binding(GO:0005522)
0.3 1.4 GO:0070097 delta-catenin binding(GO:0070097)
0.3 2.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 2.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 11.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 0.7 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2 2.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 3.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.4 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.2 7.1 GO:0008066 glutamate receptor activity(GO:0008066)
0.2 4.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 5.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.8 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 2.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 5.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.2 GO:0005537 mannose binding(GO:0005537)
0.1 4.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 1.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 2.2 GO:0005123 death receptor binding(GO:0005123)
0.1 1.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.1 6.7 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 6.1 GO:0019905 syntaxin binding(GO:0019905)
0.1 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 9.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.0 2.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 3.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 2.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877) cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 1.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 2.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 62.1 PID IL5 PATHWAY IL5-mediated signaling events
1.2 28.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 32.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.3 46.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 11.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 8.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 24.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 2.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 5.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 6.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 12.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 7.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 4.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 3.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 30.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
1.1 28.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.9 10.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.8 19.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.7 15.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.6 17.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.5 10.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.5 5.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 29.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.4 5.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 7.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 8.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 8.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 4.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 5.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 8.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.2 3.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 27.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 5.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 7.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 5.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 6.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 4.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 3.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 4.0 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport