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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SCRT1_SCRT2

Z-value: 1.35

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Transcription factors associated with SCRT1_SCRT2

Gene Symbol Gene ID Gene Info
ENSG00000261678.3 SCRT1
ENSG00000215397.4 SCRT2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SCRT1hg38_v1_chr8_-_144336451_144336503-0.221.1e-03Click!

Activity profile of SCRT1_SCRT2 motif

Sorted Z-values of SCRT1_SCRT2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SCRT1_SCRT2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_41256921 59.24 ENST00000284440.9
ENST00000508768.5
ENST00000512788.1
ubiquitin C-terminal hydrolase L1
chr4_+_41538143 31.28 ENST00000503057.6
ENST00000511496.5
LIM and calponin homology domains 1
chr6_+_121435595 29.25 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr15_-_29821473 29.13 ENST00000400011.6
tight junction protein 1
chr5_-_74640575 28.82 ENST00000651128.1
ectodermal-neural cortex 1
chr5_-_74640719 28.60 ENST00000302351.9
ENST00000509127.2
ectodermal-neural cortex 1
chr15_-_72231583 27.09 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
pyruvate kinase M1/2
chr15_-_72231113 23.55 ENST00000565154.6
ENST00000565184.6
ENST00000335181.10
pyruvate kinase M1/2
chr5_-_74640649 21.60 ENST00000537006.1
ectodermal-neural cortex 1
chr5_-_151686908 20.75 ENST00000231061.9
secreted protein acidic and cysteine rich
chrX_+_51893533 19.16 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr11_-_117876892 19.06 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr11_+_69641146 18.94 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr11_-_117876719 18.93 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr8_+_97869040 14.27 ENST00000254898.7
ENST00000524308.5
ENST00000522025.6
matrilin 2
chr1_+_15756659 14.03 ENST00000375771.5
filamin binding LIM protein 1
chr14_+_23306816 13.58 ENST00000678311.1
ENST00000557579.2
ENST00000250405.10
ENST00000679000.1
ENST00000557236.6
ENST00000678502.1
ENST00000553781.5
BCL2 like 2
BCL2L2-PABPN1 readthrough
chr8_-_126557691 12.53 ENST00000652209.1
LRAT domain containing 2
chr1_-_222712428 12.29 ENST00000355727.3
ENST00000340020.11
axin interactor, dorsalization associated
chr20_-_45348414 11.73 ENST00000372733.3
syndecan 4
chr11_-_117877463 11.73 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr15_-_29822028 11.49 ENST00000545208.6
tight junction protein 1
chr1_-_94927079 11.46 ENST00000370206.9
ENST00000394202.8
calponin 3
chr3_-_197183963 11.08 ENST00000653795.1
discs large MAGUK scaffold protein 1
chr19_-_46471407 10.70 ENST00000438932.2
PNMA family member 8A
chr5_+_126423176 10.67 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr5_+_126423363 10.58 ENST00000285689.8
GRAM domain containing 2B
chr19_-_46471484 10.18 ENST00000313683.15
ENST00000602246.1
PNMA family member 8A
chr5_+_126423122 10.12 ENST00000515200.5
GRAM domain containing 2B
chr9_+_122941003 9.96 ENST00000373647.9
ENST00000402311.5
RAB GTPase activating protein 1
chrX_+_52184874 9.39 ENST00000599522.7
ENST00000471932.6
MAGE family member D4
chrX_-_52069172 9.14 ENST00000486010.1
ENST00000497164.5
ENST00000360134.10
ENST00000485287.5
ENST00000335504.9
MAGE family member D4B
chr11_+_32091065 9.12 ENST00000054950.4
reticulocalbin 1
chr1_-_93847150 8.61 ENST00000370244.5
BCAR3 adaptor protein, NSP family member
chr6_-_56843638 8.45 ENST00000421834.6
ENST00000370788.6
dystonin
chr11_-_27722021 8.10 ENST00000314915.6
brain derived neurotrophic factor
chr11_-_111923722 8.08 ENST00000527950.5
crystallin alpha B
chr6_-_83193882 8.00 ENST00000506587.5
ENST00000507554.1
phosphoglucomutase 3
chr3_+_167735704 7.95 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr12_-_21657831 7.49 ENST00000450584.5
ENST00000350669.5
ENST00000673047.2
lactate dehydrogenase B
chr12_-_21657792 7.38 ENST00000396076.5
lactate dehydrogenase B
chr7_+_130486324 7.37 ENST00000427521.6
ENST00000378576.9
mesoderm specific transcript
chr7_+_130486171 7.32 ENST00000341441.9
ENST00000416162.7
mesoderm specific transcript
chr16_+_1989949 7.12 ENST00000248121.7
ENST00000618464.1
synaptogyrin 3
chrX_+_52184904 7.10 ENST00000375626.7
ENST00000467526.1
MAGE family member D4
chr2_+_188291854 6.79 ENST00000409830.6
GULP PTB domain containing engulfment adaptor 1
chr5_+_15500172 6.73 ENST00000504595.2
F-box and leucine rich repeat protein 7
chr15_+_43593054 6.68 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr6_-_10419638 6.58 ENST00000319516.8
transcription factor AP-2 alpha
chr3_-_42804451 6.51 ENST00000418900.6
ENST00000321331.12
ENST00000430190.5
ENST00000648550.1
HIG1 hypoxia inducible domain family member 1A
novel protein
chr4_-_5888400 6.42 ENST00000397890.6
collapsin response mediator protein 1
chr3_-_62875337 6.30 ENST00000357948.7
ENST00000612439.4
ENST00000383710.9
calcium dependent secretion activator
chr2_-_223602284 6.26 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr8_+_131939865 6.25 ENST00000520362.5
ENST00000519656.1
EFR3 homolog A
chr1_+_225777813 6.22 ENST00000619790.4
ENST00000626563.2
ENST00000304786.12
ENST00000650651.1
ENST00000366839.8
ENST00000651761.1
ENST00000366838.1
signal recognition particle 9
chr11_+_61816249 6.15 ENST00000257261.10
fatty acid desaturase 2
chr17_-_75154503 6.13 ENST00000409753.8
ENST00000581874.1
Jupiter microtubule associated homolog 1
chr9_+_111661588 6.09 ENST00000374293.5
G protein subunit gamma 10
chr2_+_37196475 5.91 ENST00000397064.6
ENST00000402297.6
ENST00000406711.5
ENST00000392061.6
ENST00000397226.2
CEBPZ opposite strand
chr3_+_133746385 5.64 ENST00000482271.5
ENST00000402696.9
transferrin
chr14_+_23306958 5.62 ENST00000554635.1
ENST00000557008.2
BCL2 like 2
BCL2L2-PABPN1 readthrough
chrX_-_153875847 5.46 ENST00000361699.8
ENST00000361981.7
L1 cell adhesion molecule
chr11_+_842807 5.46 ENST00000397411.6
tetraspanin 4
chr16_-_50368779 5.45 ENST00000394689.2
bromodomain containing 7
chr15_-_29822077 5.44 ENST00000677774.1
tight junction protein 1
chr4_-_139302516 5.43 ENST00000394228.5
ENST00000539387.5
NADH:ubiquinone oxidoreductase subunit C1
chr5_+_70049638 5.23 ENST00000511812.5
ENST00000626847.2
ENST00000380742.8
ENST00000380743.9
ENST00000638794.1
ENST00000628696.2
ENST00000614240.4
ENST00000380741.8
survival of motor neuron 2, centromeric
chr17_-_75154534 5.13 ENST00000356033.8
Jupiter microtubule associated homolog 1
chr3_-_79767987 5.02 ENST00000464233.6
roundabout guidance receptor 1
chr11_-_61891381 4.98 ENST00000525588.5
fatty acid desaturase 3
chr2_-_240820945 4.97 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
kinesin family member 1A
chr17_-_1229706 4.92 ENST00000574139.7
ABR activator of RhoGEF and GTPase
chr16_-_50368920 4.89 ENST00000394688.8
bromodomain containing 7
chr3_+_141426108 4.86 ENST00000441582.2
ENST00000510726.1
zinc finger and BTB domain containing 38
chr5_+_138753412 4.77 ENST00000520339.5
ENST00000627109.2
ENST00000302763.12
ENST00000518910.5
catenin alpha 1
chr19_-_58098203 4.75 ENST00000600845.1
ENST00000240727.10
ENST00000600897.5
ENST00000421612.6
ENST00000601063.1
ENST00000601144.6
zinc finger and SCAN domain containing 18
chr3_-_197183806 4.55 ENST00000671246.1
ENST00000660553.1
discs large MAGUK scaffold protein 1
chr6_-_31729785 4.50 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr7_-_122886706 4.31 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr15_+_43692886 4.29 ENST00000434505.5
ENST00000411750.5
creatine kinase, mitochondrial 1A
chr17_+_55266216 4.18 ENST00000573945.5
HLF transcription factor, PAR bZIP family member
chr20_+_58852710 4.13 ENST00000676826.2
ENST00000371100.9
GNAS complex locus
chr11_+_842824 4.13 ENST00000397396.5
ENST00000397397.7
tetraspanin 4
chr4_-_140427635 4.11 ENST00000325617.10
ENST00000414773.5
calmegin
chr14_+_67241531 4.10 ENST00000678380.1
membrane palmitoylated protein 5
chr17_-_42136431 4.07 ENST00000552162.5
ENST00000550504.5
RAB5C, member RAS oncogene family
chr11_+_842928 4.06 ENST00000397408.5
tetraspanin 4
chr4_-_52038260 3.91 ENST00000381431.10
sarcoglycan beta
chr14_+_67241278 3.89 ENST00000676464.1
membrane palmitoylated protein 5
chr15_-_82680407 3.82 ENST00000660624.1
ENST00000666894.1
adaptor related protein complex 3 subunit beta 2
chr5_-_111756245 3.81 ENST00000447165.6
neuronal regeneration related protein
chr6_-_31729478 3.78 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chr2_-_69387130 3.77 ENST00000674438.1
glutamine--fructose-6-phosphate transaminase 1
chr14_+_67241417 3.65 ENST00000556345.6
ENST00000555925.5
ENST00000261681.9
ENST00000557783.1
membrane palmitoylated protein 5
chr1_-_223845894 3.61 ENST00000391878.6
ENST00000343537.12
tumor protein p53 binding protein 2
chr12_-_13000166 3.49 ENST00000647702.1
heme binding protein 1
chr5_+_74715503 3.46 ENST00000513336.5
hexosaminidase subunit beta
chr6_-_31729260 3.41 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr19_+_29606274 3.37 ENST00000586420.5
ENST00000585603.6
ENST00000221770.7
ENST00000590688.1
POP4 homolog, ribonuclease P/MRP subunit
chr12_-_122422544 3.35 ENST00000358808.6
ENST00000361654.8
ENST00000539080.1
ENST00000537178.5
CAP-Gly domain containing linker protein 1
chr15_-_59657494 3.27 ENST00000396063.5
ENST00000396060.7
ENST00000396064.7
ENST00000484743.5
ENST00000559706.1
general transcription factor IIA subunit 2
chr3_+_87227257 3.23 ENST00000471660.5
ENST00000494980.5
ENST00000472024.3
ENST00000263780.9
ENST00000676705.1
charged multivesicular body protein 2B
chr1_-_156338226 3.21 ENST00000496684.6
ENST00000368259.6
ENST00000472765.6
ENST00000295688.8
ENST00000533194.5
ENST00000478640.6
chaperonin containing TCP1 subunit 3
chr7_-_28958321 3.12 ENST00000539664.3
TLR4 interactor with leucine rich repeats
chr6_-_31728877 3.06 ENST00000437288.5
dimethylarginine dimethylaminohydrolase 2
chr7_-_100100716 3.02 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chr15_-_59657468 2.97 ENST00000396061.5
general transcription factor IIA subunit 2
chr11_-_71448315 2.93 ENST00000525346.5
ENST00000531364.5
ENST00000529990.5
ENST00000527316.5
ENST00000355527.8
ENST00000407721.6
7-dehydrocholesterol reductase
chr16_+_25111703 2.91 ENST00000380966.8
ENST00000399069.8
leucine carboxyl methyltransferase 1
chr12_-_13000208 2.90 ENST00000014930.9
ENST00000536942.1
heme binding protein 1
chr3_-_197298558 2.82 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
discs large MAGUK scaffold protein 1
chr4_-_89836213 2.76 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr12_+_48818478 2.74 ENST00000547818.5
ENST00000301050.7
ENST00000547392.5
calcium voltage-gated channel auxiliary subunit beta 3
chr17_-_10198592 2.72 ENST00000432992.7
growth arrest specific 7
chr2_+_172735838 2.60 ENST00000397081.8
Rap guanine nucleotide exchange factor 4
chr1_+_62437015 2.59 ENST00000339950.5
ubiquitin specific peptidase 1
chr22_+_40346508 2.58 ENST00000636714.1
ENST00000216194.11
ENST00000623978.3
ENST00000636265.1
ENST00000680378.1
adenylosuccinate lyase
chr6_-_135497230 2.58 ENST00000681365.1
Abelson helper integration site 1
chr15_+_80060113 2.49 ENST00000618205.4
zinc finger AN1-type containing 6
chr1_+_108746654 2.48 ENST00000370008.4
syntaxin binding protein 3
chr17_-_44947637 2.46 ENST00000587309.5
ENST00000593135.6
kinesin family member 18B
chr11_+_6603740 2.44 ENST00000537806.5
ENST00000420936.6
ENST00000299421.9
ENST00000528995.5
ENST00000396751.6
integrin linked kinase
chr17_-_37745018 2.38 ENST00000613727.4
ENST00000614313.4
ENST00000617811.5
ENST00000621123.4
HNF1 homeobox B
chr11_+_6603708 2.31 ENST00000532063.5
integrin linked kinase
chr15_+_80059568 2.30 ENST00000613266.4
ENST00000561060.5
zinc finger AN1-type containing 6
chr4_+_164754116 2.29 ENST00000507311.1
small integral membrane protein 31
chr6_-_135498417 2.24 ENST00000681022.1
ENST00000680033.1
Abelson helper integration site 1
chr17_-_64263221 2.18 ENST00000258991.7
ENST00000583738.1
ENST00000584379.6
testis expressed 2
chr12_-_70754631 2.11 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
protein tyrosine phosphatase receptor type R
chr5_+_103259400 2.09 ENST00000510890.1
macrophage immunometabolism regulator
chr15_+_80059635 2.07 ENST00000559157.5
zinc finger AN1-type containing 6
chr9_+_71911615 2.06 ENST00000334731.7
ENST00000486911.2
chromosome 9 open reading frame 85
chr1_-_212414815 2.03 ENST00000261455.9
ENST00000535273.2
proton activated chloride channel 1
chr1_-_32817311 2.02 ENST00000373477.9
ENST00000675785.1
tyrosyl-tRNA synthetase 1
chr3_-_114624921 2.00 ENST00000393785.6
zinc finger and BTB domain containing 20
chr11_-_71448406 2.00 ENST00000682708.1
ENST00000683287.1
ENST00000683714.1
ENST00000682880.1
7-dehydrocholesterol reductase
chr14_-_102362714 2.00 ENST00000536961.6
ENST00000541568.6
ENST00000216756.11
cyclin dependent kinase 2 interacting protein
chr3_-_114624979 1.97 ENST00000676079.1
zinc finger and BTB domain containing 20
chr1_+_228082660 1.96 ENST00000540651.5
ENST00000272102.10
ADP ribosylation factor 1
chr2_+_172735912 1.89 ENST00000409036.5
Rap guanine nucleotide exchange factor 4
chr19_+_13906190 1.85 ENST00000318003.11
coiled-coil and C2 domain containing 1A
chr5_+_70925030 1.83 ENST00000503079.6
ENST00000514951.5
ENST00000380707.9
ENST00000506163.5
ENST00000625245.2
ENST00000351205.8
survival of motor neuron 1, telomeric
chr2_+_188291994 1.81 ENST00000409927.5
ENST00000409805.5
GULP PTB domain containing engulfment adaptor 1
chr11_-_86068743 1.75 ENST00000356360.9
phosphatidylinositol binding clathrin assembly protein
chr10_+_35195124 1.59 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
cAMP responsive element modulator
chr7_-_122886439 1.58 ENST00000412584.6
ENST00000449022.7
calcium dependent secretion activator 2
chr3_-_197298000 1.57 ENST00000664991.1
discs large MAGUK scaffold protein 1
chr11_-_104164361 1.53 ENST00000302251.9
platelet derived growth factor D
chr3_-_197183849 1.52 ENST00000443183.5
discs large MAGUK scaffold protein 1
chr5_+_141051374 1.50 ENST00000306549.6
protocadherin beta 1
chr12_-_57430956 1.43 ENST00000347140.7
ENST00000402412.5
R3H domain containing 2
chr14_+_102362931 1.41 ENST00000359520.12
tectonin beta-propeller repeat containing 2
chr7_+_12687625 1.39 ENST00000651779.1
ENST00000404894.1
ADP ribosylation factor like GTPase 4A
chr1_-_50960230 1.32 ENST00000396153.7
Fas associated factor 1
chr6_+_89562308 1.31 ENST00000522441.5
ankyrin repeat domain 6
chr1_+_179882275 1.28 ENST00000606911.7
ENST00000271583.7
torsin 1A interacting protein 1
chr3_-_186362223 1.27 ENST00000265022.8
diacylglycerol kinase gamma
chr2_+_222424520 1.27 ENST00000321276.8
sphingosine-1-phosphate phosphatase 2
chr1_+_109619827 1.27 ENST00000667949.2
ENST00000342115.8
ENST00000528667.7
adenosine monophosphate deaminase 2
chr12_-_70609788 1.26 ENST00000547715.1
ENST00000538708.5
ENST00000550857.5
ENST00000261266.9
protein tyrosine phosphatase receptor type B
chr10_+_26216665 1.19 ENST00000259271.7
glutamate decarboxylase 2
chr22_-_19479160 1.18 ENST00000399523.5
ENST00000421968.6
ENST00000263202.15
ENST00000447868.5
ubiquitin recognition factor in ER associated degradation 1
chr5_+_149271848 1.15 ENST00000296721.9
actin filament associated protein 1 like 1
chrX_-_31266925 1.06 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
dystrophin
chr4_+_88457110 1.02 ENST00000264350.8
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr9_+_128371343 1.02 ENST00000372850.5
ENST00000372847.1
ENST00000372853.9
ENST00000483206.2
ubiquitin related modifier 1
chrX_+_13689116 0.99 ENST00000464506.2
ENST00000243325.6
RAB9A, member RAS oncogene family
chr17_+_65137408 0.95 ENST00000443584.7
ENST00000449996.7
regulator of G protein signaling 9
chr19_-_5838758 0.92 ENST00000527106.5
fucosyltransferase 6
chr12_-_75511594 0.82 ENST00000438169.6
ENST00000229214.9
KRR1 small subunit processome component homolog
chr9_+_96450115 0.79 ENST00000375249.5
ENST00000375251.7
hyaluronan binding protein 4
chr11_-_117876612 0.72 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr11_+_59787067 0.71 ENST00000528805.1
syntaxin 3
chr15_+_84235773 0.64 ENST00000510439.7
ENST00000422563.6
golgin A6 family like 4
chr2_+_61017562 0.63 ENST00000401576.1
ENST00000295030.6
ENST00000414712.2
peroxisomal biogenesis factor 13
chr14_+_105419813 0.61 ENST00000435036.6
ENST00000331320.12
ENST00000406191.5
metastasis associated 1
chr5_+_32710630 0.59 ENST00000326958.5
natriuretic peptide receptor 3
chr6_+_70413417 0.57 ENST00000505769.5
ENST00000515323.5
family with sequence similarity 135 member A
chr16_+_2148603 0.55 ENST00000210187.11
RAB26, member RAS oncogene family
chr10_+_35195843 0.50 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr16_-_30011391 0.48 ENST00000616445.4
ENST00000564944.5
double C2 domain alpha
chr12_-_52517929 0.47 ENST00000548409.5
keratin 5
chr16_-_30010972 0.45 ENST00000565273.5
ENST00000567332.6
ENST00000350119.9
double C2 domain alpha
chr22_+_40346461 0.40 ENST00000623632.4
ENST00000625194.4
ENST00000637666.2
ENST00000680978.1
ENST00000623063.3
ENST00000679723.1
ENST00000342312.9
adenylosuccinate lyase
chr17_+_65137344 0.39 ENST00000262406.10
regulator of G protein signaling 9
chr11_+_70270671 0.37 ENST00000253925.12
ENST00000389547.7
PTPRF interacting protein alpha 1
chr19_+_38930916 0.36 ENST00000308018.9
ENST00000407800.2
ENST00000402029.3
mitochondrial ribosomal protein S12
chr6_-_49787265 0.29 ENST00000304801.6
phosphoglycerate kinase 2
chr10_-_100185993 0.25 ENST00000421367.7
ENST00000370408.2
ENST00000407654.7
ER lipid raft associated 1
chr2_-_240820205 0.24 ENST00000647731.1
ENST00000648680.1
ENST00000649306.1
ENST00000648129.1
ENST00000498729.9
ENST00000320389.12
ENST00000648364.1
ENST00000647885.1
ENST00000404283.9
ENST00000649096.1
kinesin family member 1A
chr3_-_72446623 0.22 ENST00000477973.4
RING1 and YY1 binding protein
chr17_+_70169516 0.16 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr19_+_40601342 0.15 ENST00000396819.8
latent transforming growth factor beta binding protein 4
chr12_+_101594849 0.06 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr6_+_70413462 0.04 ENST00000418814.7
ENST00000515280.5
ENST00000507085.5
ENST00000457062.6
ENST00000361499.7
family with sequence similarity 135 member A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.8 59.2 GO:0007412 axon target recognition(GO:0007412)
9.2 46.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
7.3 29.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
7.2 79.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
6.3 50.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
3.0 20.7 GO:0033591 response to L-ascorbic acid(GO:0033591)
2.9 11.6 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
2.7 19.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
2.7 8.1 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
2.1 6.4 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
2.0 11.7 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.8 7.2 GO:0039020 pronephric nephron tubule development(GO:0039020)
1.7 12.2 GO:1990504 dense core granule exocytosis(GO:1990504)
1.7 18.9 GO:0033327 Leydig cell differentiation(GO:0033327)
1.6 6.6 GO:0003409 optic cup structural organization(GO:0003409)
1.6 8.0 GO:0006041 glucosamine metabolic process(GO:0006041)
1.6 4.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.3 20.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
1.3 5.0 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
1.2 6.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
1.2 4.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
1.1 3.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
1.1 14.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.9 5.6 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.9 14.9 GO:0006089 lactate metabolic process(GO:0006089)
0.8 4.9 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.7 6.7 GO:0010265 SCF complex assembly(GO:0010265)
0.7 14.7 GO:0006527 arginine catabolic process(GO:0006527)
0.7 12.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.7 19.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.7 8.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.7 2.0 GO:1902822 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
0.6 3.5 GO:0007341 penetration of zona pellucida(GO:0007341)
0.6 47.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.5 11.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 1.5 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.5 2.5 GO:0022615 protein to membrane docking(GO:0022615)
0.5 8.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.5 2.8 GO:1903284 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.4 6.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.4 2.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.4 3.9 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.3 3.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.3 3.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.3 4.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.3 3.8 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3 8.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.3 4.3 GO:0006600 creatine metabolic process(GO:0006600)
0.3 3.2 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.3 4.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 1.0 GO:0034227 tRNA thio-modification(GO:0034227)
0.2 1.7 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 9.0 GO:0008089 anterograde axonal transport(GO:0008089)
0.2 5.1 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.2 3.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 3.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.2 10.3 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.2 2.7 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.2 6.7 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.2 4.7 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.2 14.3 GO:0008347 glial cell migration(GO:0008347)
0.2 1.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.2 2.9 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 2.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 4.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 7.1 GO:0021762 substantia nigra development(GO:0021762)
0.1 10.0 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 1.3 GO:0032264 IMP salvage(GO:0032264)
0.1 1.0 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.1 6.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 6.1 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 1.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.7 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 1.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 26.7 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 5.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 5.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 4.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 12.2 GO:0007498 mesoderm development(GO:0007498)
0.1 1.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 3.1 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 8.6 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 1.3 GO:0006670 sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.1 0.6 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.9 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 2.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 5.0 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.1 4.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 6.5 GO:0007422 peripheral nervous system development(GO:0007422)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 6.5 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 7.5 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 1.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 1.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 2.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 4.9 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 5.4 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.6 GO:0035272 exocrine system development(GO:0035272)
0.0 1.0 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 75.3 GO:0005921 gap junction(GO:0005921)
1.7 8.4 GO:0031673 H zone(GO:0031673)
1.6 19.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.4 29.5 GO:0043219 lateral loop(GO:0043219)
1.3 79.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.2 68.3 GO:1904115 axon cytoplasm(GO:1904115)
0.9 5.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.8 20.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.7 6.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.7 6.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.6 3.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.5 37.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.5 8.1 GO:0097512 cardiac myofibril(GO:0097512)
0.5 3.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 3.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 4.8 GO:0005915 zonula adherens(GO:0005915)
0.3 1.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 3.2 GO:0000815 ESCRT III complex(GO:0000815)
0.3 6.3 GO:0031045 dense core granule(GO:0031045)
0.3 18.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 4.8 GO:0036038 MKS complex(GO:0036038)
0.2 63.7 GO:0043209 myelin sheath(GO:0043209)
0.2 1.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 13.6 GO:0043034 costamere(GO:0043034)
0.2 5.5 GO:0044295 axonal growth cone(GO:0044295)
0.2 7.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 2.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 14.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.2 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1 6.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.7 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 2.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 14.3 GO:0005604 basement membrane(GO:0005604)
0.1 5.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 8.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 2.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 9.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 5.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.0 GO:0090544 BAF-type complex(GO:0090544)
0.1 4.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.7 GO:0042555 MCM complex(GO:0042555)
0.1 8.6 GO:0005875 microtubule associated complex(GO:0005875)
0.0 6.4 GO:0030496 midbody(GO:0030496)
0.0 1.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 3.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 4.9 GO:0072562 blood microparticle(GO:0072562)
0.0 8.0 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 6.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 4.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 7.4 GO:0000785 chromatin(GO:0000785)
0.0 13.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)
0.0 20.5 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 1.4 GO:0070820 tertiary granule(GO:0070820)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.7 50.6 GO:0004743 pyruvate kinase activity(GO:0004743)
9.9 59.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
4.9 29.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
2.1 14.9 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
2.1 14.7 GO:0016403 dimethylargininase activity(GO:0016403)
2.0 8.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.5 6.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.3 8.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.1 20.2 GO:0097016 L27 domain binding(GO:0097016)
1.0 6.2 GO:0005047 signal recognition particle binding(GO:0005047)
1.0 19.2 GO:0051400 BH domain binding(GO:0051400)
1.0 11.7 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.9 3.8 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.9 20.5 GO:0031005 filamin binding(GO:0031005)
0.7 48.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.6 18.9 GO:0070064 proline-rich region binding(GO:0070064)
0.6 5.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 2.9 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.6 3.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.5 4.3 GO:0004111 creatine kinase activity(GO:0004111)
0.5 11.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 2.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.4 5.6 GO:0008199 iron ion transmembrane transporter activity(GO:0005381) ferric iron binding(GO:0008199)
0.4 9.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 3.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 3.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 8.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 10.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 4.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 19.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 46.1 GO:0005516 calmodulin binding(GO:0005516)
0.2 1.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 1.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 4.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 7.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 4.1 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 6.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 6.3 GO:0042056 chemoattractant activity(GO:0042056)
0.2 4.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 0.9 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.2 102.5 GO:0003779 actin binding(GO:0003779)
0.1 1.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 8.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 5.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 18.5 GO:0005178 integrin binding(GO:0005178)
0.1 1.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 4.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 3.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 2.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 3.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 2.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 5.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 6.7 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.7 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1 1.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.0 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 5.6 GO:0019003 GDP binding(GO:0019003)
0.1 12.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 18.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 15.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 6.3 GO:0020037 heme binding(GO:0020037)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 2.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 32.8 GO:0042802 identical protein binding(GO:0042802)
0.0 14.7 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 5.7 GO:0008289 lipid binding(GO:0008289)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 90.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
1.1 62.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.7 29.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 27.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 17.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 4.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 8.6 PID ARF6 PATHWAY Arf6 signaling events
0.1 5.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 25.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.8 PID IL3 PATHWAY IL3-mediated signaling events
0.1 5.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 22.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 5.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 6.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 7.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 1.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 46.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.6 29.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
1.4 19.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.6 18.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.6 20.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.6 18.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.5 8.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.5 14.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.4 11.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.3 10.2 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.3 5.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 3.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 6.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 5.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 2.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 3.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 7.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 5.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 2.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 3.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 5.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 4.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 4.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 7.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 16.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 4.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 6.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 3.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 4.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 5.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 5.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.5 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 2.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 6.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 3.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 6.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives