ISMARA results: SMAD1

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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SMAD1

Z-value: 3.16

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Transcription factors associated with SMAD1

Gene Symbol	Gene ID	Gene Info
SMAD1 Ensembl NCBI GeneCards UniProt	ENSG00000170365.10	SMAD1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SMAD1	hg38_v1_chr4_+_145481845_145481871, hg38_v1_chr4_+_145482761_145482820	-0.52	1.3e-16	Click!

Activity profile of SMAD1 motif

Sorted Z-values of SMAD1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD1

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr14_-_105771405 Show fit	147.99	ENST00000641136.1 ENST00000390551.6	IGHG3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_105644790 Show fit	124.35	ENST00000641095.1 ENST00000390545.3	IGHG2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant gamma 2 (G2m marker)
chr14_-_105626066 Show fit	112.60	ENST00000641978.1 ENST00000390543.3	IGHG4 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant gamma 4 (G4m marker)
chr6_+_33080445 Show fit	89.61	ENST00000428835.5	HLA-DPB1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP beta 1
chr22_+_22895368 Show fit	85.51	ENST00000390321.2	IGLC1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 1
chr6_+_33075952 Show fit	83.33	ENST00000418931.7	HLA-DPB1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP beta 1
chr19_+_49335396 Show fit	80.83	ENST00000598095.5 ENST00000426897.6 ENST00000323906.9 ENST00000535669.6 ENST00000597602.1 ENST00000595660.1	CD37 Ensembl NCBI GeneCards UniProt Show fit	CD37 molecule
chr22_+_22899481 Show fit	77.44	ENST00000390322.2	IGLJ2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda joining 2
chr14_-_105743032 Show fit	72.21	ENST00000390548.6 ENST00000390549.6 ENST00000390542.6	IGHG1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_107775951 Show fit	71.76	ENST00000315660.8 ENST00000372384.6 ENST00000502650.1 ENST00000506724.1	TSC22D3 Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 3
chr22_+_22904850 Show fit	62.61	ENST00000390324.2	IGLJ3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda joining 3
chr2_-_89160329 Show fit	58.64	ENST00000390256.2	IGKV6-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6-21 (non-functional)
chr2_-_88992903 Show fit	55.90	ENST00000495489.1	IGKV1-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-8
chrX_-_107775740 Show fit	54.24	ENST00000372383.9	TSC22D3 Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 3
chr2_+_90038848 Show fit	49.00	ENST00000390270.2	IGKV3D-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-20
chr6_-_33080710 Show fit	48.57	ENST00000419277.5	HLA-DPA1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP alpha 1
chr9_+_136980211 Show fit	48.16	ENST00000444903.2	PTGDS Ensembl NCBI GeneCards UniProt Show fit	prostaglandin D2 synthase
chr4_-_1208825 Show fit	45.62	ENST00000511679.5 ENST00000617421.4	SPON2 Ensembl NCBI GeneCards UniProt Show fit	spondin 2
chr14_-_106507476 Show fit	40.26	ENST00000390621.3	IGHV1-45 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-45
chr14_-_105708627 Show fit	40.22	ENST00000641837.1 ENST00000390547.3	IGHA1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant alpha 1
chr6_+_31615984 Show fit	39.35	ENST00000376049.4	AIF1 Ensembl NCBI GeneCards UniProt Show fit	allograft inflammatory factor 1
chr11_+_1870252 Show fit	38.37	ENST00000612798.4	LSP1 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte specific protein 1
chr4_-_1172575 Show fit	37.59	ENST00000290902.10	SPON2 Ensembl NCBI GeneCards UniProt Show fit	spondin 2
chr6_-_31272069 Show fit	37.52	ENST00000415537.1 ENST00000376228.9 ENST00000383329.7	HLA-C Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, C
chr21_-_44910630 Show fit	37.51	ENST00000320216.10 ENST00000397852.5	ITGB2 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 2
chr19_+_1067493 Show fit	36.53	ENST00000586866.5	ARHGAP45 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 45
chr6_-_31582415 Show fit	35.82	ENST00000429299.3 ENST00000446745.2	LTB Ensembl NCBI GeneCards UniProt Show fit	lymphotoxin beta
chr22_+_22697789 Show fit	35.37	ENST00000390306.2	IGLV2-23 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-23
chr22_-_19525369 Show fit	34.98	ENST00000403084.1 ENST00000413119.2	CLDN5 Ensembl NCBI GeneCards UniProt Show fit	claudin 5
chr4_-_1173168 Show fit	34.61	ENST00000514490.5 ENST00000431380.5 ENST00000503765.5	SPON2 Ensembl NCBI GeneCards UniProt Show fit	spondin 2
chr6_+_31615215 Show fit	34.23	ENST00000337917.11 ENST00000376059.8	AIF1 Ensembl NCBI GeneCards UniProt Show fit	allograft inflammatory factor 1
chr11_+_1870150 Show fit	34.14	ENST00000429923.5 ENST00000418975.1 ENST00000406638.6	LSP1 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte specific protein 1
chr16_+_30472733 Show fit	34.11	ENST00000356798.11 ENST00000433423.2	ITGAL Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha L
chr18_-_50287816 Show fit	33.37	ENST00000589548.6 ENST00000673786.1	CXXC1 Ensembl NCBI GeneCards UniProt Show fit	CXXC finger protein 1
chr2_+_90069662 Show fit	33.00	ENST00000390271.2	IGKV6D-41 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6D-41 (non-functional)
chr2_-_89040745 Show fit	32.75	ENST00000480492.1	IGKV1-12 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-12
chr6_+_32637419 Show fit	32.51	ENST00000374949.2	HLA-DQA1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ alpha 1
chr4_-_56656507 Show fit	32.39	ENST00000381255.7 ENST00000317745.11 ENST00000555760.6 ENST00000556614.6	HOPX Ensembl NCBI GeneCards UniProt Show fit	HOP homeobox
chr16_+_172869 Show fit	31.83	ENST00000251595.11 ENST00000397806.1 ENST00000484216.1	HBA2 Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit alpha 2
chr1_-_30757767 Show fit	31.74	ENST00000294507.4	LAPTM5 Ensembl NCBI GeneCards UniProt Show fit	lysosomal protein transmembrane 5
chr13_+_30735523 Show fit	31.71	ENST00000380490.5	ALOX5AP Ensembl NCBI GeneCards UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr12_-_14951106 Show fit	31.49	ENST00000541644.5 ENST00000545895.5	ARHGDIB Ensembl NCBI GeneCards UniProt Show fit	Rho GDP dissociation inhibitor beta
chr19_+_1067144 Show fit	31.42	ENST00000313093.7	ARHGAP45 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 45
chr12_-_108633864 Show fit	30.89	ENST00000550948.2	SELPLG Ensembl NCBI GeneCards UniProt Show fit	selectin P ligand
chr9_+_136977496 Show fit	30.71	ENST00000371625.8 ENST00000457950.5	PTGDS Ensembl NCBI GeneCards UniProt Show fit	prostaglandin D2 synthase
chr11_+_121590388 Show fit	30.43	ENST00000527934.1	SORL1 Ensembl NCBI GeneCards UniProt Show fit	sortilin related receptor 1
chr22_+_22887780 Show fit	29.94	ENST00000532223.2 ENST00000526893.6 ENST00000531372.1	IGLL5 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda like polypeptide 5
chr21_-_44920855 Show fit	29.66	ENST00000397854.7	ITGB2 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 2
chr19_+_45469841 Show fit	29.66	ENST00000592811.5 ENST00000586615.5	FOSB Ensembl NCBI GeneCards UniProt Show fit	FosB proto-oncogene, AP-1 transcription factor subunit
chr6_+_29942523 Show fit	29.24	ENST00000376809.10 ENST00000376802.2 ENST00000638375.1	HLA-A Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, A
chr6_+_31587268 Show fit	28.28	ENST00000396101.7 ENST00000490742.5	LST1 Ensembl NCBI GeneCards UniProt Show fit	leukocyte specific transcript 1
chr19_+_1077394 Show fit	27.97	ENST00000590577.2	ARHGAP45 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 45
chr14_-_105856183 Show fit	27.74	ENST00000637539.2 ENST00000390559.6	IGHM Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant mu
chr2_+_89862438 Show fit	27.11	ENST00000448155.2	IGKV1D-39 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-39
chr7_+_74209386 Show fit	27.11	ENST00000344995.9	LAT2 Ensembl NCBI GeneCards UniProt Show fit	linker for activation of T cells family member 2
chr2_-_89143133 Show fit	26.98	ENST00000492167.1	IGKV3-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-20
chr17_+_39927724 Show fit	26.86	ENST00000377924.6 ENST00000578802.1 ENST00000578478.1 ENST00000582263.1	LRRC3C Ensembl NCBI GeneCards UniProt Show fit ENSG00000264968.1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 3C novel transcript
chr11_+_2302119 Show fit	26.67	ENST00000381121.7	TSPAN32 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 32
chr12_+_6946468 Show fit	26.10	ENST00000543115.5 ENST00000399448.5	PTPN6 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr13_+_30713477 Show fit	25.56	ENST00000617770.4	ALOX5AP Ensembl NCBI GeneCards UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr11_-_2301859 Show fit	25.17	ENST00000456145.2 ENST00000381153.8	C11orf21 Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 21
chr2_+_89851723 Show fit	24.99	ENST00000429992.2	IGKV2D-40 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-40
chr14_-_105940235 Show fit	24.93	ENST00000390593.2	IGHV6-1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 6-1
chr1_+_27879638 Show fit	24.92	ENST00000456990.1	THEMIS2 Ensembl NCBI GeneCards UniProt Show fit	thymocyte selection associated family member 2
chr2_-_88979016 Show fit	24.62	ENST00000390247.2	IGKV3-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_238138661 Show fit	24.46	ENST00000409223.2	KLHL30 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 30
chr18_-_50287570 Show fit	24.35	ENST00000586837.1 ENST00000412036.6 ENST00000589940.5 ENST00000587396.1 ENST00000591474.5 ENST00000285106.11	CXXC1 Ensembl NCBI GeneCards UniProt Show fit	CXXC finger protein 1
chr2_+_68365274 Show fit	24.31	ENST00000234313.8	PLEK Ensembl NCBI GeneCards UniProt Show fit	pleckstrin
chr22_+_22734577 Show fit	23.93	ENST00000390310.3	IGLV2-18 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-18
chr2_-_89100352 Show fit	23.78	ENST00000479981.1	IGKV1-16 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-16
chr19_+_41877267 Show fit	23.65	ENST00000221972.8 ENST00000597454.1 ENST00000444740.2	CD79A Ensembl NCBI GeneCards UniProt Show fit	CD79a molecule
chr1_+_161215242 Show fit	23.49	ENST00000367992.7 ENST00000289902.2	FCER1G Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgE receptor Ig
chr11_-_5234475 Show fit	23.44	ENST00000292901.7 ENST00000650601.1 ENST00000417377.1	HBD Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit delta
chr22_+_22431949 Show fit	23.14	ENST00000390301.3	IGLV1-36 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-36
chr2_-_136118142 Show fit	23.00	ENST00000241393.4	CXCR4 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine receptor 4
chr17_-_64390852 Show fit	22.85	ENST00000563924.6	PECAM1 Ensembl NCBI GeneCards UniProt Show fit	platelet and endothelial cell adhesion molecule 1
chr17_-_82317589 Show fit	22.81	ENST00000312648.8	CD7 Ensembl NCBI GeneCards UniProt Show fit	CD7 molecule
chr6_+_32741382 Show fit	22.74	ENST00000374940.4	HLA-DQA2 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ alpha 2
chr22_+_22822658 Show fit	22.36	ENST00000620395.2	IGLV2-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-8
chr6_-_25042003 Show fit	22.36	ENST00000510784.8	RIPOR2 Ensembl NCBI GeneCards UniProt Show fit	RHO family interacting cell polarization regulator 2
chr14_-_94390650 Show fit	22.33	ENST00000449399.7 ENST00000404814.8	SERPINA1 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 1
chr17_-_82317523 Show fit	22.32	ENST00000583376.1 ENST00000578509.1 ENST00000584284.5 ENST00000582480.1	CD7 Ensembl NCBI GeneCards UniProt Show fit	CD7 molecule
chr16_+_3065297 Show fit	22.13	ENST00000325568.9	IL32 Ensembl NCBI GeneCards UniProt Show fit	interleukin 32
chr1_+_152663378 Show fit	22.00	ENST00000368784.2	LCE2D Ensembl NCBI GeneCards UniProt Show fit	late cornified envelope 2D
chr16_+_3065311 Show fit	21.76	ENST00000534507.5 ENST00000613483.4 ENST00000531965.5 ENST00000396887.7	IL32 Ensembl NCBI GeneCards UniProt Show fit	interleukin 32
chr2_-_89010515 Show fit	21.74	ENST00000493819.1	IGKV1-9 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr19_+_39406831 Show fit	21.66	ENST00000597629.3 ENST00000594442.2 ENST00000594045.2	ZFP36 Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein
chr14_-_95714088 Show fit	21.62	ENST00000556450.5	TCL1A Ensembl NCBI GeneCards UniProt Show fit	TCL1 family AKT coactivator A
chr11_+_314010 Show fit	21.56	ENST00000680699.1 ENST00000681938.1 ENST00000679380.1 ENST00000680938.1 ENST00000408968.4 ENST00000681180.1 ENST00000681426.1 ENST00000680696.1	IFITM1 Ensembl NCBI GeneCards UniProt Show fit	interferon induced transmembrane protein 1
chr6_-_24877262 Show fit	21.43	ENST00000378023.8 ENST00000540914.5	RIPOR2 Ensembl NCBI GeneCards UniProt Show fit	RHO family interacting cell polarization regulator 2
chr4_-_56656448 Show fit	21.42	ENST00000553379.6	HOPX Ensembl NCBI GeneCards UniProt Show fit	HOP homeobox
chr10_+_45374204 Show fit	21.20	ENST00000374391.7	ALOX5 Ensembl NCBI GeneCards UniProt Show fit	arachidonate 5-lipoxygenase
chr22_+_22758698 Show fit	21.15	ENST00000390312.2	IGLV2-14 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-14
chr6_-_31357171 Show fit	21.11	ENST00000412585.7 ENST00000434333.1	HLA-B Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, B
chr6_+_30489501 Show fit	21.07	ENST00000376630.5	HLA-E Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, E
chr2_+_90159840 Show fit	21.03	ENST00000377032.5	IGKV1D-12 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-12
chr2_+_87338511 Show fit	21.02	ENST00000421835.2	IGKV3OR2-268 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr11_+_2301987 Show fit	20.91	ENST00000612299.4 ENST00000182290.9	TSPAN32 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 32
chr3_-_41961989 Show fit	20.83	ENST00000420927.5 ENST00000301831.9 ENST00000414606.1	ULK4 Ensembl NCBI GeneCards UniProt Show fit	unc-51 like kinase 4
chr2_+_90172802 Show fit	20.76	ENST00000390277.3	IGKV3D-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-11
chr7_+_74209989 Show fit	20.75	ENST00000361082.7 ENST00000275635.11 ENST00000460943.6 ENST00000470709.1	LAT2 Ensembl NCBI GeneCards UniProt Show fit	linker for activation of T cells family member 2
chr14_-_95714146 Show fit	20.60	ENST00000554012.5	TCL1A Ensembl NCBI GeneCards UniProt Show fit	TCL1 family AKT coactivator A
chr14_-_95714114 Show fit	20.57	ENST00000402399.6 ENST00000555202.1	TCL1A Ensembl NCBI GeneCards UniProt Show fit	TCL1 family AKT coactivator A
chr22_-_37149900 Show fit	20.48	ENST00000216223.10	IL2RB Ensembl NCBI GeneCards UniProt Show fit	interleukin 2 receptor subunit beta
chr3_-_121660892 Show fit	20.37	ENST00000428394.6 ENST00000314583.8	HCLS1 Ensembl NCBI GeneCards UniProt Show fit	hematopoietic cell-specific Lyn substrate 1
chr1_-_161631152 Show fit	20.29	ENST00000421702.3 ENST00000650385.1	FCGR3B Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG receptor IIIb
chr20_-_23086316 Show fit	20.26	ENST00000246006.5	CD93 Ensembl NCBI GeneCards UniProt Show fit	CD93 molecule
chr11_+_1868673 Show fit	20.22	ENST00000405957.6	LSP1 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte specific protein 1
chr14_-_106658251 Show fit	20.22	ENST00000454421.2	IGHV3-64 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64
chr2_+_90234809 Show fit	20.02	ENST00000443397.5	IGKV3D-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-7
chr19_+_44914588 Show fit	20.00	ENST00000592535.6	APOC1 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein C1
chr1_+_153357846 Show fit	19.94	ENST00000368738.4	S100A9 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A9
chr2_-_86790825 Show fit	19.81	ENST00000409781.1 ENST00000352580.7	CD8A Ensembl NCBI GeneCards UniProt Show fit	CD8a molecule
chr6_+_32637396 Show fit	19.81	ENST00000395363.5 ENST00000496318.5 ENST00000343139.11	HLA-DQA1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ alpha 1
chr16_+_30472700 Show fit	19.75	ENST00000358164.9	ITGAL Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha L
chr14_-_94390667 Show fit	19.74	ENST00000557492.5 ENST00000355814.8 ENST00000437397.5 ENST00000448921.5 ENST00000393088.8	SERPINA1 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 1
chr22_+_36863091 Show fit	19.73	ENST00000650698.1	NCF4 Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 4
chr1_+_32274111 Show fit	19.59	ENST00000619559.4 ENST00000461712.6 ENST00000373562.7 ENST00000477031.6 ENST00000373557.6 ENST00000333070.4	LCK Ensembl NCBI GeneCards UniProt Show fit	LCK proto-oncogene, Src family tyrosine kinase
chr1_-_202159977 Show fit	19.42	ENST00000367279.8	PTPN7 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 7
chr14_-_106185387 Show fit	19.41	ENST00000390605.2	IGHV1-18 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-18
chr19_-_54280498 Show fit	19.38	ENST00000391746.5	LILRB2 Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin like receptor B2
chr10_+_38010617 Show fit	19.29	ENST00000307441.13 ENST00000374618.7 ENST00000628825.2 ENST00000458705.6 ENST00000432900.7 ENST00000469037.2	ZNF33A Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 33A
chr6_-_73452124 Show fit	19.19	ENST00000680833.1	CGAS Ensembl NCBI GeneCards UniProt Show fit	cyclic GMP-AMP synthase
chr14_+_22547495 Show fit	19.07	ENST00000611116.2	TRAC Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha constant
chr5_-_150113344 Show fit	18.97	ENST00000286301.7 ENST00000511344.1	CSF1R Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1 receptor
chr19_+_1067272 Show fit	18.84	ENST00000590214.5	ARHGAP45 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 45
chr11_-_5227063 Show fit	18.80	ENST00000335295.4 ENST00000485743.1 ENST00000647020.1	HBB Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit beta
chr2_-_89320146 Show fit	18.71	ENST00000498574.1	IGKV1-39 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-39
chr11_+_308408 Show fit	18.66	ENST00000399815.2	ENSG00000288681.1 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr11_+_2400488 Show fit	18.56	ENST00000380996.9 ENST00000380992.5 ENST00000333256.11 ENST00000437110.5 ENST00000435795.5	TSSC4 Ensembl NCBI GeneCards UniProt Show fit	tumor suppressing subtransferable candidate 4
chr2_-_86790900 Show fit	18.50	ENST00000283635.8	CD8A Ensembl NCBI GeneCards UniProt Show fit	CD8a molecule
chr14_-_106715166 Show fit	18.49	ENST00000390633.2	IGHV1-69 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69
chr1_+_12019460 Show fit	18.46	ENST00000235332.6	MIIP Ensembl NCBI GeneCards UniProt Show fit	migration and invasion inhibitory protein
chr6_-_166956561 Show fit	18.44	ENST00000366855.10	RNASET2 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease T2
chr19_-_35740535 Show fit	18.42	ENST00000591748.1	IGFLR1 Ensembl NCBI GeneCards UniProt Show fit	IGF like family receptor 1
chr19_+_47309853 Show fit	18.42	ENST00000355085.4	C5AR1 Ensembl NCBI GeneCards UniProt Show fit	complement C5a receptor 1
chr16_+_3065348 Show fit	18.36	ENST00000529699.5 ENST00000526464.6 ENST00000440815.7 ENST00000529550.5	IL32 Ensembl NCBI GeneCards UniProt Show fit	interleukin 32
chr6_+_31586835 Show fit	18.09	ENST00000211921.11	LST1 Ensembl NCBI GeneCards UniProt Show fit	leukocyte specific transcript 1
chr22_+_22327298 Show fit	18.09	ENST00000390291.2	IGLV1-50 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-50 (non-functional)
chr14_-_94390614 Show fit	18.07	ENST00000553327.5 ENST00000556955.5 ENST00000557118.5 ENST00000440909.5	SERPINA1 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 1
chr12_+_6789508 Show fit	18.04	ENST00000011653.9 ENST00000541982.5 ENST00000539492.1	CD4 Ensembl NCBI GeneCards UniProt Show fit	CD4 molecule
chr19_-_3801791 Show fit	18.04	ENST00000590849.1 ENST00000395045.6	MATK Ensembl NCBI GeneCards UniProt Show fit	megakaryocyte-associated tyrosine kinase
chr7_-_150800320 Show fit	17.96	ENST00000492607.5 ENST00000326442.10 ENST00000450753.2	TMEM176B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 176B
chr5_-_170297746 Show fit	17.71	ENST00000046794.10	LCP2 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte cytosolic protein 2
chr11_-_61917490 Show fit	17.53	ENST00000394836.7	RAB3IL1 Ensembl NCBI GeneCards UniProt Show fit	RAB3A interacting protein like 1
chr14_-_106422175 Show fit	17.53	ENST00000390619.2	IGHV4-39 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-39
chr9_+_136979042 Show fit	17.49	ENST00000446677.2	PTGDS Ensembl NCBI GeneCards UniProt Show fit	prostaglandin D2 synthase
chr22_+_22792485 Show fit	17.37	ENST00000390314.2	IGLV2-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-11
chr19_+_18173804 Show fit	17.36	ENST00000407280.4	IFI30 Ensembl NCBI GeneCards UniProt Show fit	IFI30 lysosomal thiol reductase
chr14_-_106737547 Show fit	17.28	ENST00000632209.1	IGHV1-69-2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69-2
chr15_+_81299416 Show fit	17.27	ENST00000558332.3	IL16 Ensembl NCBI GeneCards UniProt Show fit	interleukin 16
chr12_+_6951345 Show fit	17.23	ENST00000318974.14 ENST00000541698.5 ENST00000542462.1	PTPN6 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr1_-_169711603 Show fit	17.16	ENST00000236147.6 ENST00000650983.1	SELL Ensembl NCBI GeneCards UniProt Show fit	selectin L
chr19_-_51372640 Show fit	17.11	ENST00000600427.5 ENST00000221978.10	NKG7 Ensembl NCBI GeneCards UniProt Show fit	natural killer cell granule protein 7
chr15_+_81296913 Show fit	17.10	ENST00000394652.6	IL16 Ensembl NCBI GeneCards UniProt Show fit	interleukin 16
chr16_-_66552460 Show fit	17.07	ENST00000678015.1 ENST00000569718.6 ENST00000678314.1 ENST00000562484.2	TK2 Ensembl NCBI GeneCards UniProt Show fit	thymidine kinase 2
chr16_+_1240698 Show fit	17.01	ENST00000561736.2 ENST00000338844.8 ENST00000461509.6	TPSAB1 Ensembl NCBI GeneCards UniProt Show fit	tryptase alpha/beta 1
chr12_+_120725796 Show fit	16.88	ENST00000242592.9 ENST00000411593.2	ACADS Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA dehydrogenase short chain
chr10_+_80408503 Show fit	16.74	ENST00000606162.6	PRXL2A Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin like 2A
chr15_-_78944985 Show fit	16.57	ENST00000615999.5 ENST00000677789.1 ENST00000676880.1 ENST00000677936.1 ENST00000220166.10 ENST00000677810.1 ENST00000678644.1 ENST00000677534.1 ENST00000677316.1	CTSH Ensembl NCBI GeneCards UniProt Show fit	cathepsin H
chr15_-_21742799 Show fit	16.52	ENST00000622410.2	ENSG00000278263.2 Ensembl NCBI GeneCards UniProt Show fit	novel protein, identical to IGHV4-4
chr3_+_88059231 Show fit	16.49	ENST00000636215.2	ZNF654 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 654
chr3_-_50338226 Show fit	16.46	ENST00000395126.7	RASSF1 Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 1
chr10_+_11165475 Show fit	16.43	ENST00000609692.5 ENST00000354897.3	CELF2 Ensembl NCBI GeneCards UniProt Show fit	CUGBP Elav-like family member 2
chr19_-_51372269 Show fit	16.43	ENST00000593572.5 ENST00000595157.1	NKG7 Ensembl NCBI GeneCards UniProt Show fit	natural killer cell granule protein 7
chr15_+_88638947 Show fit	16.37	ENST00000559876.2	ISG20 Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chrX_+_71366290 Show fit	16.31	ENST00000683782.1 ENST00000423759.6	TAF1 Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 1
chrX_-_107777038 Show fit	16.30	ENST00000480691.2 ENST00000506081.5 ENST00000514426.1	TSC22D3 Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 3
chr18_+_79679775 Show fit	16.29	ENST00000613122.5 ENST00000075430.11	CTDP1 Ensembl NCBI GeneCards UniProt Show fit	CTD phosphatase subunit 1
chr22_+_22922594 Show fit	16.26	ENST00000390331.3	IGLC7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 7
chr10_+_45374167 Show fit	16.07	ENST00000542434.5	ALOX5 Ensembl NCBI GeneCards UniProt Show fit	arachidonate 5-lipoxygenase
chr11_+_121576760 Show fit	15.96	ENST00000532694.5 ENST00000534286.5	SORL1 Ensembl NCBI GeneCards UniProt Show fit	sortilin related receptor 1
chr5_-_42825884 Show fit	15.95	ENST00000506577.5	SELENOP Ensembl NCBI GeneCards UniProt Show fit	selenoprotein P
chr2_+_68774782 Show fit	15.92	ENST00000409030.7 ENST00000409220.5	ARHGAP25 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 25
chr13_+_41457543 Show fit	15.89	ENST00000379359.4	RGCC Ensembl NCBI GeneCards UniProt Show fit	regulator of cell cycle
chr14_-_106025628 Show fit	15.88	ENST00000631943.1	IGHV7-4-1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 7-4-1
chr14_-_106277039 Show fit	15.87	ENST00000390610.2	IGHV1-24 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-24
chr2_-_89213917 Show fit	15.78	ENST00000498435.1	IGKV1-27 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-27
chr2_+_90082635 Show fit	15.77	ENST00000483379.1	IGKV1D-17 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-17
chr1_-_27635176 Show fit	15.75	ENST00000374005.8	FGR Ensembl NCBI GeneCards UniProt Show fit	FGR proto-oncogene, Src family tyrosine kinase
chr9_-_134917872 Show fit	15.74	ENST00000616356.4 ENST00000371806.4	FCN1 Ensembl NCBI GeneCards UniProt Show fit	ficolin 1
chr1_+_192575765 Show fit	15.72	ENST00000469578.2 ENST00000367459.8	RGS1 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 1
chr19_+_8413270 Show fit	15.70	ENST00000381035.8 ENST00000595142.5 ENST00000601724.5 ENST00000601283.5 ENST00000215555.7 ENST00000595213.1	MARCHF2 Ensembl NCBI GeneCards UniProt Show fit	membrane associated ring-CH-type finger 2
chr19_-_35908247 Show fit	15.70	ENST00000585901.6 ENST00000544690.6 ENST00000424586.7 ENST00000262629.9 ENST00000589517.1	TYROBP Ensembl NCBI GeneCards UniProt Show fit	transmembrane immune signaling adaptor TYROBP
chr1_+_152675295 Show fit	15.64	ENST00000368783.1	LCE2C Ensembl NCBI GeneCards UniProt Show fit	late cornified envelope 2C
chrX_+_47078330 Show fit	15.60	ENST00000457380.5	RGN Ensembl NCBI GeneCards UniProt Show fit	regucalcin
chr6_-_166956537 Show fit	15.60	ENST00000508775.6	RNASET2 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease T2
chr15_-_19988117 Show fit	15.57	ENST00000558565.2	IGHV3OR15-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr17_-_17972374 Show fit	15.50	ENST00000318094.14 ENST00000540946.5 ENST00000379504.8 ENST00000542206.5 ENST00000395739.8 ENST00000581396.5 ENST00000535933.5 ENST00000579586.1	TOM1L2 Ensembl NCBI GeneCards UniProt Show fit	target of myb1 like 2 membrane trafficking protein
chr5_+_55102635 Show fit	15.49	ENST00000274306.7	GZMA Ensembl NCBI GeneCards UniProt Show fit	granzyme A
chr12_-_3873346 Show fit	15.47	ENST00000427057.6	PARP11 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 11
chr11_-_67437670 Show fit	15.42	ENST00000326294.4	PTPRCAP Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type C associated protein
chr9_-_94639473 Show fit	15.41	ENST00000375326.9	FBP1 Ensembl NCBI GeneCards UniProt Show fit	fructose-bisphosphatase 1
chr16_+_33802683 Show fit	15.37	ENST00000570121.2	IGHV3OR16-12 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr16_+_3065380 Show fit	15.36	ENST00000551122.5 ENST00000548807.5 ENST00000528163.6	IL32 Ensembl NCBI GeneCards UniProt Show fit	interleukin 32
chr10_-_133276836 Show fit	15.32	ENST00000415217.7	ADAM8 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 8
chr15_-_21718245 Show fit	15.29	ENST00000630556.1	ENSG00000281179.1 Ensembl NCBI GeneCards UniProt Show fit	novel gene identicle to IGHV1OR15-1
chr19_-_54364863 Show fit	15.23	ENST00000348231.8	LAIR1 Ensembl NCBI GeneCards UniProt Show fit	leukocyte associated immunoglobulin like receptor 1
chr14_-_105588322 Show fit	15.20	ENST00000497872.4 ENST00000390539.2	IGHA2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant alpha 2 (A2m marker)
chrX_-_153926220 Show fit	15.06	ENST00000370016.5	ARHGAP4 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.6	149.0	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
15.5	46.4	GO:1902948	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
13.7	137.3	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
13.7	68.5	GO:0014738	regulation of muscle hyperplasia(GO:0014738)
13.7	1027.8	GO:0006910	phagocytosis, recognition(GO:0006910)
12.8	64.1	GO:1903904	negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
12.2	36.7	GO:0002892	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
11.8	129.8	GO:0043152	induction of bacterial agglutination(GO:0043152)
11.7	58.7	GO:0033277	abortive mitotic cell cycle(GO:0033277)
10.8	43.4	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
10.6	42.4	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
10.5	31.5	GO:0071461	cellular response to redox state(GO:0071461)
10.3	10.3	GO:1901074	regulation of engulfment of apoptotic cell(GO:1901074)
10.1	30.3	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
10.1	80.5	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
10.0	39.9	GO:0045659	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
9.8	39.3	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
9.4	37.6	GO:0050902	leukocyte adhesive activation(GO:0050902)
9.3	46.3	GO:0072535	tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307)
9.2	27.5	GO:0030185	nitric oxide transport(GO:0030185)
9.0	36.2	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
9.0	9.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
8.9	26.7	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
8.9	8.9	GO:1903004	regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
8.9	26.6	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
8.6	25.8	GO:0001869	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
8.4	67.4	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
8.3	24.8	GO:2000417	negative regulation of eosinophil migration(GO:2000417)
8.1	32.4	GO:0036369	transcription factor catabolic process(GO:0036369)
8.1	32.3	GO:1903631	regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
7.9	71.1	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
7.6	22.9	GO:0038178	complement component C5a signaling pathway(GO:0038178)
7.6	30.2	GO:0005986	sucrose biosynthetic process(GO:0005986)
7.4	29.6	GO:1905224	clathrin-coated pit assembly(GO:1905224)
7.4	22.1	GO:2000564	CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
7.2	136.6	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
7.1	21.4	GO:0033364	mast cell secretory granule organization(GO:0033364)
6.8	6.8	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
6.8	6.8	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
6.8	635.3	GO:0006958	complement activation, classical pathway(GO:0006958)
6.7	20.2	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
6.5	13.0	GO:0032661	regulation of interleukin-18 production(GO:0032661)
6.5	25.9	GO:0002357	defense response to tumor cell(GO:0002357)
6.5	45.2	GO:0070560	protein secretion by platelet(GO:0070560)
6.4	6.4	GO:0002442	serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
6.2	24.8	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
6.2	24.7	GO:0050712	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
6.1	12.3	GO:1905237	response to cyclosporin A(GO:1905237)
6.1	61.0	GO:2001300	lipoxin metabolic process(GO:2001300)
6.1	6.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
5.9	17.8	GO:0038156	interleukin-3-mediated signaling pathway(GO:0038156)
5.8	11.5	GO:0001812	regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
5.7	22.8	GO:0072011	diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
5.6	39.2	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
5.5	16.6	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
5.5	16.4	GO:2000754	regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
5.4	16.2	GO:0002818	intracellular defense response(GO:0002818)
5.4	16.2	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
5.3	37.3	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
5.3	15.9	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
5.2	20.8	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
5.2	5.2	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
5.2	31.0	GO:0036102	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
5.1	106.7	GO:0019371	cyclooxygenase pathway(GO:0019371)
5.0	5.0	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
4.9	4.9	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
4.9	4.9	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
4.9	4.9	GO:0010872	regulation of cholesterol esterification(GO:0010872)
4.9	14.6	GO:0070844	misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
4.8	24.1	GO:0044855	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
4.5	17.9	GO:0050757	thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
4.4	22.0	GO:0044027	hypermethylation of CpG island(GO:0044027)
4.4	13.2	GO:0061011	hepatic duct development(GO:0061011)
4.4	13.2	GO:0051673	pore formation in membrane of other organism(GO:0035915) membrane disruption in other organism(GO:0051673)
4.3	17.3	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
4.3	4.3	GO:0060290	transdifferentiation(GO:0060290)
4.3	12.8	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
4.2	12.7	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
4.2	12.6	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
4.2	8.4	GO:0006258	UDP-glucose catabolic process(GO:0006258)
4.2	12.5	GO:1904884	telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
4.2	4.2	GO:0070662	mast cell proliferation(GO:0070662)
4.1	8.2	GO:0071464	cellular response to hydrostatic pressure(GO:0071464)
4.1	4.1	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763)
4.1	4.1	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
4.1	16.3	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
4.0	24.3	GO:0046092	deoxycytidine metabolic process(GO:0046092)
4.0	60.4	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
4.0	15.9	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
3.9	15.7	GO:0019082	viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
3.9	11.8	GO:0006982	response to lipid hydroperoxide(GO:0006982)
3.9	3.9	GO:0006498	N-terminal protein lipidation(GO:0006498)
3.8	11.5	GO:0001983	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
3.8	23.0	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
3.8	15.2	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
3.8	15.2	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
3.8	7.6	GO:0002767	immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
3.8	3.8	GO:0032058	positive regulation of translation in response to stress(GO:0032056) positive regulation of translational initiation in response to stress(GO:0032058)
3.8	3.8	GO:0036245	cellular response to menadione(GO:0036245)
3.7	22.4	GO:0038016	insulin receptor internalization(GO:0038016)
3.7	14.9	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
3.7	11.1	GO:0030573	bile acid catabolic process(GO:0030573)
3.7	22.0	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
3.6	10.9	GO:0006683	galactosylceramide catabolic process(GO:0006683)
3.6	47.2	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
3.6	79.3	GO:0001829	trophectodermal cell differentiation(GO:0001829)
3.6	10.7	GO:1902528	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
3.5	14.2	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
3.5	3.5	GO:0032423	regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
3.5	21.1	GO:0019732	antifungal humoral response(GO:0019732)
3.5	20.9	GO:0061737	leukotriene signaling pathway(GO:0061737)
3.5	13.8	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
3.4	10.3	GO:0071529	cementum mineralization(GO:0071529)
3.4	34.4	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
3.4	17.1	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
3.3	6.7	GO:0002314	germinal center B cell differentiation(GO:0002314)
3.3	10.0	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
3.3	10.0	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
3.3	13.3	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
3.3	9.9	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
3.3	6.6	GO:0075071	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
3.3	9.9	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
3.3	13.1	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
3.3	3.3	GO:1902567	negative regulation of eosinophil activation(GO:1902567)
3.3	32.8	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
3.3	3.3	GO:2000410	regulation of thymocyte migration(GO:2000410)
3.3	9.8	GO:0010046	response to mycotoxin(GO:0010046)
3.3	6.5	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
3.2	19.5	GO:0015680	intracellular copper ion transport(GO:0015680)
3.2	376.7	GO:0031295	T cell costimulation(GO:0031295)
3.2	25.3	GO:0015705	iodide transport(GO:0015705)
3.2	31.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
3.2	25.2	GO:0001887	selenium compound metabolic process(GO:0001887)
3.1	6.3	GO:0071421	manganese ion transmembrane transport(GO:0071421)
3.1	9.4	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
3.1	6.2	GO:1903236	regulation of leukocyte tethering or rolling(GO:1903236)
3.1	12.4	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
3.1	3.1	GO:0071910	determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
3.1	24.7	GO:0070995	NADPH oxidation(GO:0070995)
3.1	3.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
3.1	9.2	GO:0034769	basement membrane disassembly(GO:0034769)
3.0	3.0	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
3.0	3.0	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
3.0	9.0	GO:0009720	detection of hormone stimulus(GO:0009720) detection of endogenous stimulus(GO:0009726)
3.0	9.0	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
3.0	18.0	GO:1903936	cellular response to sodium arsenite(GO:1903936)
3.0	8.9	GO:0061289	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
3.0	3.0	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
3.0	53.4	GO:0015671	oxygen transport(GO:0015671)
2.9	5.9	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
2.9	29.1	GO:0006116	NADH oxidation(GO:0006116)
2.9	14.4	GO:0032494	response to peptidoglycan(GO:0032494)
2.9	20.2	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
2.9	2.9	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
2.9	20.0	GO:0015811	L-cystine transport(GO:0015811)
2.8	14.2	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
2.8	8.5	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
2.8	2.8	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
2.8	5.6	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
2.8	16.6	GO:0043366	beta selection(GO:0043366)
2.8	19.4	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
2.8	2.8	GO:0097476	spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
2.7	2.7	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
2.7	8.2	GO:0032954	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
2.7	10.9	GO:1902283	negative regulation of primary amine oxidase activity(GO:1902283)
2.7	19.0	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
2.7	8.1	GO:1902310	positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.7	8.1	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
2.7	10.7	GO:0035900	response to isolation stress(GO:0035900)
2.7	8.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
2.6	13.2	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
2.6	5.3	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
2.6	76.3	GO:0045730	respiratory burst(GO:0045730)
2.6	13.1	GO:1904674	positive regulation of somatic stem cell population maintenance(GO:1904674)
2.6	18.2	GO:0045007	depurination(GO:0045007)
2.6	20.8	GO:0098543	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
2.6	7.8	GO:0060366	subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
2.6	2.6	GO:0007060	male meiosis chromosome segregation(GO:0007060)
2.6	5.2	GO:0003218	cardiac left ventricle formation(GO:0003218)
2.6	7.7	GO:1901097	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of autophagosome maturation(GO:1901097)
2.5	17.6	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
2.5	7.5	GO:0009609	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) positive regulation of fibril organization(GO:1902905)
2.5	12.4	GO:0032074	negative regulation of nuclease activity(GO:0032074)
2.5	5.0	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
2.5	138.4	GO:0050853	B cell receptor signaling pathway(GO:0050853)
2.5	12.3	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
2.4	4.9	GO:0071104	response to interleukin-9(GO:0071104)
2.4	9.5	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
2.4	33.2	GO:2001204	regulation of osteoclast development(GO:2001204)
2.4	21.3	GO:0045217	cell-cell junction maintenance(GO:0045217)
2.4	7.1	GO:0002384	hepatic immune response(GO:0002384)
2.4	4.7	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
2.3	16.4	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
2.3	7.0	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
2.3	32.8	GO:0043117	positive regulation of vascular permeability(GO:0043117)
2.3	11.7	GO:1901563	response to camptothecin(GO:1901563)
2.3	14.0	GO:1905065	positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
2.3	2.3	GO:0007183	SMAD protein complex assembly(GO:0007183)
2.3	4.7	GO:0061582	intestinal epithelial cell migration(GO:0061582)
2.3	4.7	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.3	9.3	GO:0009227	UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
2.3	9.3	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
2.3	2.3	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
2.3	9.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
2.3	4.6	GO:0070842	aggresome assembly(GO:0070842)
2.3	27.7	GO:0048251	elastic fiber assembly(GO:0048251)
2.3	2.3	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
2.3	13.8	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
2.3	4.6	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
2.3	6.9	GO:0018094	protein polyglycylation(GO:0018094)
2.3	4.6	GO:0060374	mast cell differentiation(GO:0060374)
2.3	6.9	GO:0036090	cleavage furrow ingression(GO:0036090)
2.3	20.6	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
2.3	11.3	GO:0045023	G0 to G1 transition(GO:0045023)
2.3	4.5	GO:0036269	swimming behavior(GO:0036269)
2.2	15.7	GO:0034587	piRNA metabolic process(GO:0034587)
2.2	6.7	GO:0003406	retinal pigment epithelium development(GO:0003406)
2.2	9.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
2.2	49.0	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
2.2	6.7	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
2.2	8.9	GO:0071918	urea transmembrane transport(GO:0071918)
2.2	13.3	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
2.2	4.4	GO:0015840	urea transport(GO:0015840)
2.2	10.9	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
2.2	2.2	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
2.2	47.8	GO:0050930	induction of positive chemotaxis(GO:0050930)
2.2	19.6	GO:0002227	innate immune response in mucosa(GO:0002227)
2.2	6.5	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
2.2	15.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
2.2	6.5	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
2.1	17.1	GO:0006013	mannose metabolic process(GO:0006013)
2.1	6.4	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
2.1	21.3	GO:0018377	protein myristoylation(GO:0018377)
2.1	4.2	GO:1904529	regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
2.1	14.8	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
2.1	10.5	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
2.1	2.1	GO:2000399	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
2.1	14.5	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
2.0	8.1	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
2.0	6.1	GO:0097032	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
2.0	26.3	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
2.0	4.0	GO:0043974	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
2.0	2.0	GO:0072209	metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
2.0	9.9	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
2.0	19.8	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
2.0	5.9	GO:1903027	regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
1.9	5.8	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
1.9	13.5	GO:1903912	negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
1.9	5.7	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.9	3.8	GO:1903413	cellular response to bile acid(GO:1903413)
1.9	32.5	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
1.9	34.0	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
1.9	1.9	GO:1902410	mitotic cytokinetic process(GO:1902410)
1.9	20.8	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.9	5.6	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
1.9	31.6	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
1.8	5.5	GO:0043379	memory T cell differentiation(GO:0043379)
1.8	9.2	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
1.8	5.5	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
1.8	29.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
1.8	5.5	GO:0042631	cellular response to water deprivation(GO:0042631)
1.8	3.6	GO:0071907	determination of digestive tract left/right asymmetry(GO:0071907)
1.8	112.5	GO:0006968	cellular defense response(GO:0006968)
1.8	1.8	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
1.8	7.2	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.8	7.2	GO:0009822	alkaloid catabolic process(GO:0009822)
1.8	257.4	GO:0002377	immunoglobulin production(GO:0002377)
1.8	5.4	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
1.8	7.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
1.8	1.8	GO:1904779	regulation of protein localization to centrosome(GO:1904779)
1.8	1.8	GO:0046110	purine nucleobase catabolic process(GO:0006145) xanthine metabolic process(GO:0046110)
1.8	3.5	GO:0045819	positive regulation of glycogen catabolic process(GO:0045819)
1.8	8.8	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.8	8.8	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
1.8	7.0	GO:0043335	protein unfolding(GO:0043335)
1.7	7.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
1.7	5.2	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
1.7	5.2	GO:0070269	pyroptosis(GO:0070269)
1.7	3.4	GO:0048852	hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
1.7	20.6	GO:0006824	cobalt ion transport(GO:0006824)
1.7	6.9	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
1.7	6.9	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
1.7	12.0	GO:0018095	protein polyglutamylation(GO:0018095)
1.7	20.5	GO:0042738	exogenous drug catabolic process(GO:0042738)
1.7	15.3	GO:0002315	marginal zone B cell differentiation(GO:0002315)
1.7	13.6	GO:0072719	cellular response to cisplatin(GO:0072719)
1.7	1.7	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
1.7	11.9	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
1.7	6.6	GO:2000297	negative regulation of synapse maturation(GO:2000297)
1.6	6.6	GO:1903182	regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
1.6	14.8	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
1.6	8.2	GO:0044245	polysaccharide digestion(GO:0044245)
1.6	22.9	GO:0032495	response to muramyl dipeptide(GO:0032495)
1.6	1.6	GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
1.6	3.3	GO:2000583	regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
1.6	9.8	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
1.6	3.3	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
1.6	3.2	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
1.6	6.4	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.6	8.0	GO:1900121	negative regulation of receptor binding(GO:1900121)
1.6	8.0	GO:0072708	response to sorbitol(GO:0072708)
1.6	38.4	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
1.6	11.2	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
1.6	6.4	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
1.6	8.0	GO:0030259	lipid glycosylation(GO:0030259)
1.6	14.3	GO:0001661	conditioned taste aversion(GO:0001661)
1.6	4.7	GO:0016256	N-glycan processing to lysosome(GO:0016256)
1.6	22.1	GO:1990845	adaptive thermogenesis(GO:1990845)
1.6	6.3	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.6	10.9	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
1.6	4.7	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
1.6	3.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
1.6	9.4	GO:0007000	nucleolus organization(GO:0007000)
1.6	1.6	GO:0010840	regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
1.6	7.8	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
1.5	3.1	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684)
1.5	1.5	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
1.5	6.2	GO:1905229	cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
1.5	3.1	GO:1905075	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.5	9.2	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.5	6.1	GO:0030910	optic placode formation(GO:0001743) olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.5	12.2	GO:0001554	luteolysis(GO:0001554)
1.5	7.6	GO:0030242	pexophagy(GO:0030242)
1.5	4.6	GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
1.5	6.0	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
1.5	3.0	GO:0002215	defense response to nematode(GO:0002215)
1.5	1.5	GO:0042137	sequestering of neurotransmitter(GO:0042137)
1.5	3.0	GO:0061056	sclerotome development(GO:0061056)
1.5	4.4	GO:0033700	phospholipid efflux(GO:0033700)
1.5	4.4	GO:1905063	myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) regulation of vascular smooth muscle cell differentiation(GO:1905063) negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
1.5	4.4	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
1.5	11.7	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
1.5	4.4	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
1.5	4.4	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.5	14.6	GO:0007320	insemination(GO:0007320)
1.4	8.7	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
1.4	10.1	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.4	4.3	GO:0046968	peptide antigen transport(GO:0046968)
1.4	8.6	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
1.4	1.4	GO:0035634	response to stilbenoid(GO:0035634)
1.4	7.1	GO:2000318	positive regulation of T-helper 17 type immune response(GO:2000318)
1.4	11.3	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
1.4	7.1	GO:2000870	oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
1.4	5.6	GO:0032306	regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
1.4	2.8	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
1.4	9.8	GO:0061370	testosterone biosynthetic process(GO:0061370)
1.4	2.8	GO:0051464	positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
1.4	22.3	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
1.4	9.7	GO:0045910	negative regulation of DNA recombination(GO:0045910)
1.4	5.6	GO:0010430	fatty acid omega-oxidation(GO:0010430)
1.4	19.5	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.4	4.2	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
1.4	13.9	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.4	6.9	GO:0006041	glucosamine metabolic process(GO:0006041)
1.4	4.1	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
1.4	55.0	GO:0018149	peptide cross-linking(GO:0018149)
1.4	6.9	GO:1901526	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.4	2.7	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.3	2.7	GO:0042133	neurotransmitter metabolic process(GO:0042133)
1.3	18.9	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
1.3	5.4	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
1.3	5.4	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
1.3	1.3	GO:0007521	muscle cell fate determination(GO:0007521)
1.3	5.3	GO:0051037	regulation of transcription involved in meiotic cell cycle(GO:0051037)
1.3	2.7	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
1.3	13.3	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.3	6.6	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
1.3	7.9	GO:0072672	neutrophil extravasation(GO:0072672)
1.3	4.0	GO:1904640	response to methionine(GO:1904640)
1.3	2.6	GO:0021558	trochlear nerve development(GO:0021558)
1.3	69.9	GO:0006953	acute-phase response(GO:0006953)
1.3	2.6	GO:1900191	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
1.3	2.6	GO:0006288	base-excision repair, DNA ligation(GO:0006288)
1.3	6.6	GO:0031022	nuclear migration along microfilament(GO:0031022)
1.3	3.9	GO:0030327	prenylated protein catabolic process(GO:0030327)
1.3	20.8	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
1.3	13.0	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
1.3	9.1	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
1.3	9.1	GO:0002074	extraocular skeletal muscle development(GO:0002074)
1.3	3.9	GO:1904017	cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.3	6.4	GO:0071557	histone H3-K27 demethylation(GO:0071557)
1.3	2.6	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
1.3	6.4	GO:0031860	telomeric 3' overhang formation(GO:0031860)
1.3	5.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
1.3	2.6	GO:1901079	positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899)
1.3	6.4	GO:0048102	autophagic cell death(GO:0048102)
1.3	5.1	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
1.3	1.3	GO:0035963	cellular response to interleukin-13(GO:0035963)
1.3	7.6	GO:0060481	lobar bronchus epithelium development(GO:0060481)
1.3	3.8	GO:1903465	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.3	3.8	GO:0018343	protein farnesylation(GO:0018343)
1.3	3.8	GO:2000252	negative regulation of feeding behavior(GO:2000252)
1.3	7.5	GO:0033088	immature T cell proliferation in thymus(GO:0033080) regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.3	5.0	GO:0006477	protein sulfation(GO:0006477)
1.2	2.5	GO:0042414	epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
1.2	2.5	GO:0002879	positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
1.2	4.9	GO:0009305	protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
1.2	7.4	GO:0035617	stress granule disassembly(GO:0035617)
1.2	4.9	GO:0015942	formate metabolic process(GO:0015942)
1.2	20.9	GO:0097186	amelogenesis(GO:0097186)
1.2	3.7	GO:0046603	negative regulation of mitotic centrosome separation(GO:0046603)
1.2	8.5	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.2	4.9	GO:0050957	equilibrioception(GO:0050957)
1.2	16.9	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
1.2	30.2	GO:0006706	steroid catabolic process(GO:0006706)
1.2	2.4	GO:0009438	methylglyoxal metabolic process(GO:0009438)
1.2	2.4	GO:0002266	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
1.2	10.7	GO:0098535	de novo centriole assembly(GO:0098535)
1.2	15.3	GO:0010668	ectodermal cell differentiation(GO:0010668)
1.2	16.5	GO:2000291	regulation of myoblast proliferation(GO:2000291)
1.2	4.7	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
1.2	3.5	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
1.2	10.6	GO:0060075	regulation of resting membrane potential(GO:0060075)
1.2	9.4	GO:0086043	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
1.2	65.6	GO:0032945	negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
1.2	12.9	GO:0086103	G-protein coupled receptor signaling pathway involved in heart process(GO:0086103)
1.2	5.8	GO:0002286	T cell activation involved in immune response(GO:0002286)
1.2	8.1	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
1.2	3.5	GO:0045554	TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
1.2	54.5	GO:0051568	histone H3-K4 methylation(GO:0051568)
1.2	3.5	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
1.1	14.9	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617)
1.1	4.6	GO:1904749	regulation of protein localization to nucleolus(GO:1904749)
1.1	8.0	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
1.1	2.3	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.1	3.4	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
1.1	3.4	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
1.1	6.8	GO:0006540	glutamate decarboxylation to succinate(GO:0006540)
1.1	5.6	GO:0010615	positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.1	1.1	GO:2000182	regulation of progesterone biosynthetic process(GO:2000182)
1.1	2.3	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
1.1	18.0	GO:0019835	cytolysis(GO:0019835)
1.1	19.1	GO:0007398	ectoderm development(GO:0007398)
1.1	4.5	GO:0090230	regulation of centromere complex assembly(GO:0090230)
1.1	4.5	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
1.1	1.1	GO:1905225	response to thyrotropin-releasing hormone(GO:1905225)
1.1	12.3	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
1.1	2.2	GO:0015819	lysine transport(GO:0015819) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transport(GO:1902022) L-lysine import into cell(GO:1903410)
1.1	3.3	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
1.1	4.4	GO:0033602	gamma-aminobutyric acid catabolic process(GO:0009450) negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of dopamine secretion(GO:0033602) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
1.1	2.2	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
1.1	10.0	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
1.1	3.3	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
1.1	4.4	GO:1990502	dense core granule maturation(GO:1990502)
1.1	2.2	GO:0002730	regulation of dendritic cell cytokine production(GO:0002730)
1.1	5.5	GO:0035995	detection of muscle stretch(GO:0035995)
1.1	9.9	GO:0034058	endosomal vesicle fusion(GO:0034058)
1.1	3.3	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
1.1	3.3	GO:0003430	growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431)
1.1	1.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
1.1	1.1	GO:0019376	galactolipid catabolic process(GO:0019376)
1.1	7.6	GO:0045110	intermediate filament bundle assembly(GO:0045110)
1.1	3.3	GO:0009085	lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
1.1	1.1	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
1.1	3.2	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
1.1	3.2	GO:0051918	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of fibrinolysis(GO:0051918)
1.1	1.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
1.1	5.3	GO:2000382	positive regulation of mesoderm development(GO:2000382)
1.1	2.1	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.1	10.7	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
1.1	2.1	GO:0010820	positive regulation of T cell chemotaxis(GO:0010820)
1.1	29.8	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
1.1	4.2	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
1.1	2.1	GO:1990637	response to prolactin(GO:1990637)
1.1	4.2	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
1.0	27.2	GO:0032007	negative regulation of TOR signaling(GO:0032007)
1.0	4.2	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
1.0	2.1	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
1.0	31.2	GO:0097503	sialylation(GO:0097503)
1.0	2.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
1.0	6.2	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
1.0	4.1	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.0	4.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
1.0	6.2	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
1.0	9.2	GO:0051567	histone H3-K9 methylation(GO:0051567)
1.0	6.1	GO:0032445	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
1.0	2.0	GO:0051599	response to hydrostatic pressure(GO:0051599)
1.0	4.1	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
1.0	4.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
1.0	5.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
1.0	5.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.0	9.1	GO:0045054	constitutive secretory pathway(GO:0045054)
1.0	1.0	GO:0042737	drug catabolic process(GO:0042737)
1.0	6.1	GO:0042780	tRNA 3'-end processing(GO:0042780)
1.0	10.1	GO:0015074	DNA integration(GO:0015074)
1.0	3.0	GO:0051941	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) regulation of calcium:sodium antiporter activity(GO:1903279)
1.0	6.0	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
1.0	1.0	GO:0032971	regulation of muscle filament sliding(GO:0032971)
1.0	9.0	GO:0006069	ethanol oxidation(GO:0006069)
1.0	3.0	GO:0009804	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
1.0	3.9	GO:0046618	drug export(GO:0046618)
1.0	17.7	GO:0055003	cardiac myofibril assembly(GO:0055003)
1.0	1.0	GO:0023035	CD40 signaling pathway(GO:0023035)
1.0	3.9	GO:0048266	behavioral response to pain(GO:0048266)
1.0	19.6	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
1.0	4.8	GO:0052203	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.0	7.7	GO:0070544	histone H3-K36 demethylation(GO:0070544)
1.0	1.9	GO:0090135	actin filament branching(GO:0090135)
1.0	16.4	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
1.0	3.8	GO:0007512	adult heart development(GO:0007512)
1.0	1.0	GO:0000023	maltose metabolic process(GO:0000023)
1.0	17.2	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
1.0	5.7	GO:0051694	pointed-end actin filament capping(GO:0051694)
1.0	6.7	GO:0060452	positive regulation of cardiac muscle contraction(GO:0060452)
1.0	7.6	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.9	2.8	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.9	4.7	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.9	2.8	GO:0036233	glycine import(GO:0036233)
0.9	4.7	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.9	30.0	GO:0016601	Rac protein signal transduction(GO:0016601)
0.9	1.9	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.9	2.8	GO:0002933	lipid hydroxylation(GO:0002933)
0.9	7.4	GO:0060973	cell migration involved in heart development(GO:0060973)
0.9	7.4	GO:0007506	gonadal mesoderm development(GO:0007506)
0.9	7.4	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.9	4.6	GO:1905146	lysosomal protein catabolic process(GO:1905146)
0.9	40.3	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.9	5.5	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.9	4.6	GO:0035624	receptor transactivation(GO:0035624)
0.9	2.7	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.9	7.3	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.9	7.3	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.9	2.7	GO:0021571	rhombomere 5 development(GO:0021571) rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.9	3.6	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.9	5.4	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.9	1.8	GO:1902949	positive regulation of tau-protein kinase activity(GO:1902949)
0.9	14.3	GO:0055026	negative regulation of cardiac muscle tissue development(GO:0055026)
0.9	2.7	GO:0061107	seminal vesicle development(GO:0061107)
0.9	4.4	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.9	4.4	GO:2000169	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.9	6.2	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483)
0.9	4.4	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
0.9	9.7	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.9	4.4	GO:0010816	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.9	2.6	GO:0099526	presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.9	2.6	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.9	47.9	GO:0015701	bicarbonate transport(GO:0015701)
0.9	5.2	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.9	28.6	GO:0032570	response to progesterone(GO:0032570)
0.9	1.7	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.9	13.7	GO:0042116	macrophage activation(GO:0042116)
0.9	13.7	GO:0070208	protein heterotrimerization(GO:0070208)
0.9	6.9	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.9	1.7	GO:0015740	C4-dicarboxylate transport(GO:0015740)
0.8	3.4	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.8	3.4	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.8	1.7	GO:1902218	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.8	4.2	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.8	144.1	GO:0002250	adaptive immune response(GO:0002250)
0.8	11.6	GO:0006693	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.8	9.9	GO:0072520	seminiferous tubule development(GO:0072520)
0.8	1.7	GO:0001757	somite specification(GO:0001757)
0.8	1.7	GO:0003064	regulation of heart rate by hormone(GO:0003064)
0.8	14.8	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.8	4.9	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.8	19.7	GO:0009994	oocyte differentiation(GO:0009994)
0.8	2.5	GO:1902988	neurofibrillary tangle assembly(GO:1902988)
0.8	7.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.8	1.6	GO:0001575	globoside metabolic process(GO:0001575)
0.8	4.9	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.8	0.8	GO:2001223	negative regulation of neuron migration(GO:2001223)
0.8	1.6	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.8	21.9	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.8	5.7	GO:0097120	receptor localization to synapse(GO:0097120)
0.8	7.3	GO:0001675	acrosome assembly(GO:0001675)
0.8	8.0	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.8	7.2	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.8	3.2	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.8	4.8	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.8	7.2	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.8	8.0	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.8	11.1	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.8	10.3	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.8	2.4	GO:0071206	establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.8	8.7	GO:0014029	neural crest formation(GO:0014029)
0.8	3.2	GO:0010157	response to chlorate(GO:0010157)
0.8	4.7	GO:0021633	optic nerve structural organization(GO:0021633)
0.8	2.4	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.8	2.4	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.8	19.5	GO:0010574	regulation of vascular endothelial growth factor production(GO:0010574)
0.8	3.9	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.8	38.0	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.8	3.9	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.8	11.6	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.8	0.8	GO:0042938	dipeptide transport(GO:0042938)
0.8	3.1	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.8	16.8	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.8	26.7	GO:0010107	potassium ion import(GO:0010107)
0.8	6.9	GO:0010755	regulation of plasminogen activation(GO:0010755)
0.8	2.3	GO:1901078	negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.8	16.6	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.8	18.8	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.8	9.8	GO:0035641	locomotory exploration behavior(GO:0035641)
0.8	4.5	GO:0015816	glycine transport(GO:0015816)
0.8	6.0	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.8	3.0	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.8	7.5	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.8	2.3	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.7	10.5	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.7	14.2	GO:0006853	carnitine shuttle(GO:0006853)
0.7	33.7	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.7	9.0	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.7	4.5	GO:0060081	membrane hyperpolarization(GO:0060081)
0.7	8.2	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.7	1.5	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.7	1.5	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.7	2.2	GO:0002143	tRNA wobble position uridine thiolation(GO:0002143)
0.7	2.9	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.7	14.5	GO:0035456	response to interferon-beta(GO:0035456)
0.7	2.2	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.7	2.2	GO:1903347	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.7	5.8	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.7	2.2	GO:0035483	negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.7	12.2	GO:0009299	mRNA transcription(GO:0009299)
0.7	3.6	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.7	3.6	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.7	7.8	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.7	43.4	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.7	5.7	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.7	3.5	GO:0001714	endodermal cell fate specification(GO:0001714)
0.7	16.9	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.7	4.9	GO:0060215	primitive hemopoiesis(GO:0060215)
0.7	2.8	GO:1904100	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.7	3.4	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.7	1.4	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.7	5.5	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.7	2.7	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
0.7	2.0	GO:0032364	oxygen homeostasis(GO:0032364)
0.7	9.5	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.7	1.4	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.7	4.7	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
0.7	6.7	GO:0051014	actin filament severing(GO:0051014)
0.7	4.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.7	4.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.7	1.3	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.7	1.3	GO:0002507	tolerance induction(GO:0002507)
0.7	1.3	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.7	12.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.7	6.0	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.7	6.0	GO:0060033	anatomical structure regression(GO:0060033)
0.7	3.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.7	19.8	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.7	4.6	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.7	1.3	GO:2000812	regulation of barbed-end actin filament capping(GO:2000812)
0.7	10.5	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.7	1.3	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.7	2.6	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.7	11.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.6	5.1	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.6	3.2	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.6	1.9	GO:0042412	taurine biosynthetic process(GO:0042412)
0.6	1.9	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.6	5.1	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.6	1.9	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.6	3.8	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.6	5.7	GO:0050691	regulation of defense response to virus by host(GO:0050691)
0.6	1.3	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.6	9.5	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.6	3.1	GO:0033058	directional locomotion(GO:0033058)
0.6	4.4	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.6	3.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049) cardiolipin acyl-chain remodeling(GO:0035965)
0.6	8.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.6	2.5	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6	3.7	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.6	4.3	GO:0007143	female meiotic division(GO:0007143)
0.6	10.4	GO:0005513	detection of calcium ion(GO:0005513)
0.6	1.8	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.6	4.2	GO:0006568	tryptophan metabolic process(GO:0006568)
0.6	4.2	GO:0007549	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.6	4.2	GO:1903003	regulation of protein deubiquitination(GO:0090085) positive regulation of protein deubiquitination(GO:1903003)
0.6	3.6	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.6	4.2	GO:0080009	mRNA methylation(GO:0080009)
0.6	5.4	GO:0031053	primary miRNA processing(GO:0031053)
0.6	44.1	GO:1902476	chloride transmembrane transport(GO:1902476)
0.6	4.1	GO:0090527	actin filament reorganization(GO:0090527)
0.6	18.7	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.6	2.3	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.6	4.1	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.6	2.3	GO:0035633	maintenance of blood-brain barrier(GO:0035633) regulation of metalloendopeptidase activity(GO:1904683)
0.6	4.6	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.6	6.4	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.6	8.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.6	2.3	GO:0060039	pericardium development(GO:0060039)
0.6	5.7	GO:0010225	response to UV-C(GO:0010225)
0.6	10.2	GO:0060561	apoptotic process involved in morphogenesis(GO:0060561)
0.6	1.1	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.6	1.7	GO:0015860	purine nucleoside transmembrane transport(GO:0015860)
0.6	1.7	GO:0051541	elastin metabolic process(GO:0051541)
0.6	2.8	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.6	1.7	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.6	2.2	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.6	8.4	GO:0060736	prostate gland growth(GO:0060736)
0.6	2.2	GO:0060017	parathyroid gland development(GO:0060017)
0.6	6.1	GO:0030238	male sex determination(GO:0030238)
0.6	2.8	GO:0036337	Fas signaling pathway(GO:0036337)
0.6	2.8	GO:1904526	regulation of microtubule binding(GO:1904526)
0.6	1.7	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.6	0.6	GO:0046533	negative regulation of photoreceptor cell differentiation(GO:0046533) negative regulation of oligodendrocyte differentiation(GO:0048715)
0.5	2.2	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.5	8.1	GO:0045821	positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.5	3.8	GO:0061709	reticulophagy(GO:0061709)
0.5	6.5	GO:2000505	regulation of energy homeostasis(GO:2000505)
0.5	5.4	GO:0039536	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) negative regulation of RIG-I signaling pathway(GO:0039536)
0.5	3.8	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.5	1.1	GO:0019323	pentose catabolic process(GO:0019323)
0.5	1.1	GO:0035564	regulation of kidney size(GO:0035564) regulation of pronephros size(GO:0035565)
0.5	1.6	GO:2000706	dense core granule biogenesis(GO:0061110) amniotic stem cell differentiation(GO:0097086) regulation of dense core granule biogenesis(GO:2000705) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.5	0.5	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.5	2.6	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5	33.8	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.5	5.2	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451)
0.5	10.4	GO:0050909	sensory perception of taste(GO:0050909)
0.5	3.6	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.5	2.1	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.5	2.0	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.5	10.2	GO:0046710	GDP metabolic process(GO:0046710)
0.5	10.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.5	4.0	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.5	2.0	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.5	1.0	GO:0051450	myoblast proliferation(GO:0051450)
0.5	6.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.5	2.0	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.5	1.0	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.5	16.7	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.5	2.0	GO:0030916	otic vesicle formation(GO:0030916)
0.5	2.4	GO:0072553	terminal button organization(GO:0072553)
0.5	12.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.5	1.5	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.5	6.8	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.5	1.9	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.5	1.9	GO:0097646	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.5	6.6	GO:1905038	regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.5	5.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.5	3.8	GO:0010002	cardioblast differentiation(GO:0010002)
0.5	2.8	GO:0006543	glutamine catabolic process(GO:0006543)
0.5	0.9	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.5	5.2	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.5	2.8	GO:0035063	nuclear speck organization(GO:0035063)
0.5	3.2	GO:0046950	cellular ketone body metabolic process(GO:0046950)
0.5	3.7	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.5	1.4	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.4	0.9	GO:0061188	regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.4	1.8	GO:0045760	positive regulation of action potential(GO:0045760)
0.4	6.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.4	2.7	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.4	2.2	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.4	1.3	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.4	2.2	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
0.4	4.4	GO:0051923	sulfation(GO:0051923)
0.4	2.2	GO:0030903	notochord development(GO:0030903)
0.4	10.5	GO:0030488	tRNA methylation(GO:0030488)
0.4	1.3	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.4	1.3	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.4	5.1	GO:0032094	response to food(GO:0032094)
0.4	0.8	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.4	1.7	GO:0009439	cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.4	5.1	GO:0019731	antibacterial humoral response(GO:0019731)
0.4	3.0	GO:0018342	protein prenylation(GO:0018342) protein geranylgeranylation(GO:0018344) prenylation(GO:0097354)
0.4	2.1	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.4	12.8	GO:0031641	regulation of myelination(GO:0031641)
0.4	2.1	GO:0021590	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.4	0.4	GO:0044565	dendritic cell proliferation(GO:0044565)
0.4	0.8	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.4	0.8	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.4	1.2	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.4	2.4	GO:0022605	ovarian cumulus expansion(GO:0001550) oogenesis stage(GO:0022605) fused antrum stage(GO:0048165)
0.4	1.2	GO:1902490	regulation of sperm capacitation(GO:1902490)
0.4	1.2	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.4	5.2	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.4	2.8	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.4	5.9	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4	4.3	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.4	3.9	GO:0035095	behavioral response to nicotine(GO:0035095)
0.4	1.2	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.4	2.7	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.4	2.7	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.4	126.0	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.4	2.3	GO:0008218	bioluminescence(GO:0008218)
0.4	2.3	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.4	3.8	GO:0016576	histone dephosphorylation(GO:0016576)
0.4	1.1	GO:0006857	oligopeptide transport(GO:0006857)
0.4	7.2	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.4	1.1	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.4	3.3	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
0.4	1.5	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.4	2.6	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.4	21.2	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.4	9.3	GO:0030279	negative regulation of ossification(GO:0030279)
0.4	7.1	GO:0043171	peptide catabolic process(GO:0043171)
0.4	4.2	GO:0003338	metanephros morphogenesis(GO:0003338)
0.4	1.8	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.3	3.5	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.3	1.4	GO:0015813	acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.3	2.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.3	11.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3	8.3	GO:0015698	inorganic anion transport(GO:0015698)
0.3	3.4	GO:2001222	regulation of neuron migration(GO:2001222)
0.3	33.9	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3	3.0	GO:0032790	ribosome disassembly(GO:0032790)
0.3	4.3	GO:0018298	protein-chromophore linkage(GO:0018298)
0.3	2.7	GO:0015693	magnesium ion transport(GO:0015693)
0.3	11.2	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.3	4.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.3	3.5	GO:0048665	neuron fate specification(GO:0048665)
0.3	2.6	GO:0045124	regulation of bone resorption(GO:0045124)
0.3	1.0	GO:0090131	mesenchyme migration(GO:0090131)
0.3	1.9	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3	3.4	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.3	1.2	GO:1904569	regulation of selenocysteine incorporation(GO:1904569)
0.3	1.2	GO:0023041	neuronal signal transduction(GO:0023041)
0.3	4.0	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.3	3.0	GO:0019730	antimicrobial humoral response(GO:0019730)
0.3	3.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.3	3.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.3	0.6	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.3	5.7	GO:0043507	positive regulation of JUN kinase activity(GO:0043507)
0.3	2.1	GO:0044065	regulation of respiratory system process(GO:0044065)
0.3	5.1	GO:0007140	male meiosis(GO:0007140)
0.3	4.1	GO:0046626	regulation of insulin receptor signaling pathway(GO:0046626)
0.3	1.7	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.3	2.2	GO:0002021	response to dietary excess(GO:0002021)
0.3	1.7	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.3	3.3	GO:0034389	lipid particle organization(GO:0034389)
0.3	3.6	GO:1900744	regulation of p38MAPK cascade(GO:1900744)
0.3	0.5	GO:0001659	temperature homeostasis(GO:0001659)
0.3	3.3	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.3	3.0	GO:0051661	maintenance of centrosome location(GO:0051661)
0.3	0.8	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.3	0.8	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.3	13.5	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.3	6.4	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.3	1.3	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.3	7.7	GO:0006198	cAMP catabolic process(GO:0006198)
0.2	13.7	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.2	0.5	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.2	2.0	GO:0061365	positive regulation of triglyceride lipase activity(GO:0061365)
0.2	1.0	GO:0006004	fucose metabolic process(GO:0006004)
0.2	0.7	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.2	0.7	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2	0.9	GO:0032486	Rap protein signal transduction(GO:0032486)
0.2	1.9	GO:0071763	nuclear membrane organization(GO:0071763)
0.2	1.2	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.2	4.8	GO:0046849	bone remodeling(GO:0046849)
0.2	1.4	GO:0016554	cytidine to uridine editing(GO:0016554)
0.2	0.7	GO:0098911	regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.2	0.9	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959) regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2	7.3	GO:1901185	negative regulation of ERBB signaling pathway(GO:1901185)
0.2	0.9	GO:0034334	adherens junction maintenance(GO:0034334)
0.2	4.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2	6.5	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.2	3.7	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.2	1.1	GO:0097396	response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.2	0.8	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2	1.4	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.2	1.2	GO:0001977	renal system process involved in regulation of blood volume(GO:0001977)
0.2	0.4	GO:1901018	positive regulation of potassium ion transmembrane transporter activity(GO:1901018)
0.2	3.4	GO:0097264	self proteolysis(GO:0097264)
0.2	1.4	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.2	2.3	GO:0055010	ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.2	1.1	GO:0006050	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.2	1.3	GO:0072319	synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319)
0.2	0.4	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.2	3.6	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.2	1.4	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.2	0.7	GO:2000194	regulation of female gonad development(GO:2000194)
0.2	0.2	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.2	1.5	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.2	1.9	GO:0042417	dopamine metabolic process(GO:0042417)
0.2	18.5	GO:0007265	Ras protein signal transduction(GO:0007265)
0.2	0.3	GO:0072313	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2	2.8	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.2	0.5	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.1	1.2	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.9	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1	2.0	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.1	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.1	0.9	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.7	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1	1.0	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1	0.4	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) peripheral nervous system neuron axonogenesis(GO:0048936)
0.1	2.3	GO:0048753	pigment granule organization(GO:0048753)
0.1	0.9	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.4	GO:1901052	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1	0.4	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1	0.3	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.1	0.9	GO:0021516	dorsal spinal cord development(GO:0021516)
0.1	0.9	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.1	0.5	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.1	2.0	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	0.4	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.4	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1	0.9	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1	0.5	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1	0.7	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.1	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.1	0.1	GO:1902474	regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
0.1	0.5	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.1	4.8	GO:0070268	cornification(GO:0070268)
0.1	0.2	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1	0.2	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0	0.1	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.0	0.1	GO:0036510	trimming of terminal mannose on C branch(GO:0036510)
0.0	0.2	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0	0.2	GO:0030043	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) actin filament fragmentation(GO:0030043) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0	0.5	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.2	GO:0098838	methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0	1.0	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.1	GO:0043605	cellular amide catabolic process(GO:0043605)
0.0	0.8	GO:0097352	autophagosome maturation(GO:0097352)
0.0	0.4	GO:0001947	heart looping(GO:0001947) embryonic heart tube morphogenesis(GO:0003143)
0.0	0.1	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.2	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.1	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.0	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0	0.0	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
27.7	27.7	GO:0071753	IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
24.8	149.0	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
20.6	82.4	GO:0071748	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
19.0	913.0	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
17.9	340.2	GO:0042613	MHC class II protein complex(GO:0042613)
12.0	132.3	GO:0042612	MHC class I protein complex(GO:0042612)
8.8	26.3	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
8.5	33.9	GO:0005602	complement component C1 complex(GO:0005602)
7.4	52.0	GO:0032010	phagolysosome(GO:0032010)
7.4	7.4	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
7.1	35.5	GO:0019815	B cell receptor complex(GO:0019815)
7.1	42.5	GO:0097013	phagocytic vesicle lumen(GO:0097013)
6.8	74.9	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
5.9	29.5	GO:0036398	TCR signalosome(GO:0036398)
5.9	64.8	GO:0060171	stereocilium membrane(GO:0060171)
5.1	15.3	GO:0070701	mucus layer(GO:0070701)
5.0	15.0	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
5.0	29.8	GO:1990584	cardiac Troponin complex(GO:1990584)
5.0	24.9	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
4.9	24.7	GO:1990031	pinceau fiber(GO:1990031)
4.9	29.2	GO:0044194	cytolytic granule(GO:0044194)
4.7	18.8	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
4.5	63.4	GO:0048188	Set1C/COMPASS complex(GO:0048188)
4.2	71.2	GO:0042101	T cell receptor complex(GO:0042101)
4.2	25.0	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
4.1	77.8	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
4.0	15.9	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
4.0	98.9	GO:0001891	phagocytic cup(GO:0001891)
3.9	15.7	GO:0071546	pi-body(GO:0071546)
3.8	15.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
3.5	46.1	GO:0005833	hemoglobin complex(GO:0005833)
3.4	65.4	GO:0005641	nuclear envelope lumen(GO:0005641)
3.3	63.6	GO:0042629	mast cell granule(GO:0042629)
3.2	15.9	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
3.2	19.0	GO:1990682	CSF1-CSF1R complex(GO:1990682)
3.1	15.7	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
3.1	12.5	GO:0030430	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
3.1	21.7	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
2.9	5.8	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
2.8	33.8	GO:0097486	multivesicular body lumen(GO:0097486)
2.8	2.8	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
2.7	10.8	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
2.7	37.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
2.7	8.0	GO:0070195	growth hormone receptor complex(GO:0070195)
2.6	23.8	GO:0071953	elastic fiber(GO:0071953)
2.6	10.5	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
2.6	142.2	GO:0001772	immunological synapse(GO:0001772)
2.6	12.9	GO:0001652	granular component(GO:0001652)
2.4	12.2	GO:1990761	growth cone lamellipodium(GO:1990761)
2.4	19.5	GO:0035976	AP1 complex(GO:0035976)
2.4	17.0	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
2.4	4.8	GO:0061689	tricellular tight junction(GO:0061689)
2.3	53.5	GO:0042627	chylomicron(GO:0042627)
2.3	16.2	GO:0033391	chromatoid body(GO:0033391)
2.2	4.4	GO:0030991	intraciliary transport particle A(GO:0030991)
2.2	8.7	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
2.1	12.9	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
2.1	313.2	GO:0072562	blood microparticle(GO:0072562)
2.1	6.2	GO:0000805	X chromosome(GO:0000805)
2.1	33.0	GO:0031089	platelet dense granule lumen(GO:0031089)
2.0	14.3	GO:1990745	EARP complex(GO:1990745)
2.0	18.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
2.0	2.0	GO:0035061	interchromatin granule(GO:0035061)
2.0	5.9	GO:0031251	PAN complex(GO:0031251)
1.9	13.5	GO:1990111	spermatoproteasome complex(GO:1990111)
1.9	69.2	GO:0008305	integrin complex(GO:0008305)
1.9	17.1	GO:0070652	HAUS complex(GO:0070652)
1.8	11.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.8	10.9	GO:0033553	rDNA heterochromatin(GO:0033553)
1.8	5.4	GO:0033263	CORVET complex(GO:0033263)
1.8	7.1	GO:0070876	SOSS complex(GO:0070876)
1.8	5.3	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
1.7	10.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
1.7	8.6	GO:0005577	fibrinogen complex(GO:0005577)
1.7	57.9	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
1.7	5.0	GO:0097637	intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
1.6	6.6	GO:1990356	sumoylated E2 ligase complex(GO:1990356)
1.6	159.4	GO:0070821	tertiary granule membrane(GO:0070821)
1.6	6.5	GO:1990879	CST complex(GO:1990879)
1.6	19.2	GO:0097512	cardiac myofibril(GO:0097512)
1.6	9.4	GO:1990769	proximal neuron projection(GO:1990769)
1.5	4.6	GO:0030312	external encapsulating structure(GO:0030312)
1.5	187.8	GO:0035578	azurophil granule lumen(GO:0035578)
1.5	3.0	GO:0032797	SMN complex(GO:0032797)
1.5	13.5	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.5	37.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
1.5	7.3	GO:0034464	BBSome(GO:0034464)
1.4	10.1	GO:0070436	Grb2-EGFR complex(GO:0070436)
1.4	7.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.4	14.1	GO:0035253	ciliary rootlet(GO:0035253)
1.4	7.0	GO:0032302	MutSbeta complex(GO:0032302)
1.4	24.8	GO:0031092	platelet alpha granule membrane(GO:0031092)
1.4	11.0	GO:1903440	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
1.4	20.6	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.4	5.5	GO:0000801	central element(GO:0000801)
1.4	13.5	GO:0046581	intercellular canaliculus(GO:0046581)
1.3	10.7	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.3	9.2	GO:0072687	meiotic spindle(GO:0072687)
1.3	11.5	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
1.3	44.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
1.3	7.6	GO:0070545	PeBoW complex(GO:0070545)
1.3	2.5	GO:1990622	CHOP-ATF3 complex(GO:1990622)
1.3	7.5	GO:0032584	growth cone membrane(GO:0032584)
1.3	6.3	GO:0032299	ribonuclease H2 complex(GO:0032299)
1.2	6.2	GO:0089701	U2AF(GO:0089701)
1.2	3.7	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
1.2	56.8	GO:0001533	cornified envelope(GO:0001533)
1.2	4.9	GO:0097443	sorting endosome(GO:0097443)
1.2	9.8	GO:0043203	axon hillock(GO:0043203)
1.2	15.6	GO:0097413	Lewy body(GO:0097413)
1.2	3.6	GO:0032590	dendrite membrane(GO:0032590)
1.2	4.7	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
1.2	11.7	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
1.2	5.9	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.2	22.2	GO:0030014	CCR4-NOT complex(GO:0030014)
1.2	41.7	GO:0034451	centriolar satellite(GO:0034451)
1.2	5.8	GO:0045179	apical cortex(GO:0045179)
1.1	17.0	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
1.1	4.5	GO:0033596	TSC1-TSC2 complex(GO:0033596)
1.1	4.5	GO:0031905	early endosome lumen(GO:0031905)
1.1	3.3	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
1.1	4.4	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
1.1	2.2	GO:0097209	epidermal lamellar body(GO:0097209)
1.1	6.5	GO:0044327	dendritic spine head(GO:0044327)
1.1	48.2	GO:0016235	aggresome(GO:0016235)
1.1	17.0	GO:0031904	endosome lumen(GO:0031904)
1.0	119.9	GO:0005796	Golgi lumen(GO:0005796)
1.0	3.1	GO:0034657	GID complex(GO:0034657)
1.0	1.0	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.0	4.1	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
1.0	5.0	GO:0032444	activin responsive factor complex(GO:0032444)
1.0	3.0	GO:0035525	NF-kappaB p50/p65 complex(GO:0035525)
1.0	3.0	GO:0097165	nuclear stress granule(GO:0097165)
1.0	4.9	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
1.0	8.7	GO:0032059	bleb(GO:0032059)
1.0	70.4	GO:0043202	lysosomal lumen(GO:0043202)
1.0	5.8	GO:0005594	collagen type IX trimer(GO:0005594)
1.0	68.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.9	13.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.9	37.7	GO:0016592	mediator complex(GO:0016592)
0.9	5.6	GO:0002177	manchette(GO:0002177)
0.9	3.7	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.9	4.6	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.9	5.4	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.9	15.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.9	2.7	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.9	2.6	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.9	4.4	GO:0031310	intrinsic component of vacuolar membrane(GO:0031310)
0.9	2.6	GO:0099569	cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.9	0.9	GO:0014802	terminal cisterna(GO:0014802)
0.9	2.6	GO:0071821	FANCM-MHF complex(GO:0071821)
0.8	15.1	GO:0036038	MKS complex(GO:0036038)
0.8	25.8	GO:0034706	sodium channel complex(GO:0034706)
0.8	2.5	GO:0097224	sperm connecting piece(GO:0097224)
0.8	2.5	GO:0098536	deuterosome(GO:0098536)
0.8	5.7	GO:0060077	inhibitory synapse(GO:0060077)
0.8	3.2	GO:0036449	microtubule minus-end(GO:0036449)
0.8	20.1	GO:0032982	myosin filament(GO:0032982)
0.8	15.7	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.8	3.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.8	4.6	GO:0097452	GAIT complex(GO:0097452)
0.8	3.8	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.7	3.0	GO:1990393	3M complex(GO:1990393)
0.7	179.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.7	3.0	GO:0044307	dendritic branch(GO:0044307)
0.7	2.2	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.7	8.1	GO:0031083	BLOC-1 complex(GO:0031083)
0.7	3.7	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.7	5.1	GO:0000974	Prp19 complex(GO:0000974)
0.7	3.7	GO:0030314	junctional membrane complex(GO:0030314)
0.7	10.8	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.7	2.2	GO:0031933	telomeric heterochromatin(GO:0031933)
0.7	5.5	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.7	2.0	GO:0005745	m-AAA complex(GO:0005745)
0.7	7.4	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.7	3.9	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.6	28.6	GO:0035579	specific granule membrane(GO:0035579)
0.6	10.8	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.6	16.5	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.6	2.5	GO:0045298	tubulin complex(GO:0045298)
0.6	1.8	GO:0035189	Rb-E2F complex(GO:0035189)
0.6	5.5	GO:0044294	dendritic growth cone(GO:0044294)
0.6	10.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.6	9.7	GO:0031528	microvillus membrane(GO:0031528)
0.6	3.0	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.6	2.4	GO:0030137	COPI-coated vesicle(GO:0030137)
0.6	1.8	GO:0070695	FHF complex(GO:0070695)
0.6	65.8	GO:0031225	anchored component of membrane(GO:0031225)
0.6	8.0	GO:0016461	unconventional myosin complex(GO:0016461)
0.6	2.3	GO:0005879	axonemal microtubule(GO:0005879)
0.6	8.6	GO:0097225	sperm midpiece(GO:0097225)
0.6	3.4	GO:0044530	supraspliceosomal complex(GO:0044530)
0.6	2.2	GO:0035363	histone locus body(GO:0035363)
0.6	2.8	GO:0036157	outer dynein arm(GO:0036157)
0.6	39.0	GO:0005581	collagen trimer(GO:0005581)
0.6	2.2	GO:0036128	CatSper complex(GO:0036128)
0.6	2.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.6	31.4	GO:0016459	myosin complex(GO:0016459)
0.5	642.5	GO:0005615	extracellular space(GO:0005615)
0.5	1.6	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.5	3.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.5	3.7	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.5	1.5	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.5	5.5	GO:0030870	Mre11 complex(GO:0030870)
0.5	4.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.5	11.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.5	5.2	GO:0097427	microtubule bundle(GO:0097427)
0.5	49.1	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.5	11.0	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5	14.7	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.5	2.3	GO:0030897	HOPS complex(GO:0030897)
0.5	4.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4	2.7	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4	1.8	GO:0005579	membrane attack complex(GO:0005579)
0.4	3.1	GO:0042788	polysomal ribosome(GO:0042788)
0.4	6.6	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4	5.7	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.4	1.7	GO:0071564	npBAF complex(GO:0071564)
0.4	74.5	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.4	15.6	GO:0005902	microvillus(GO:0005902)
0.4	5.0	GO:0016013	syntrophin complex(GO:0016013)
0.4	5.3	GO:0017119	Golgi transport complex(GO:0017119)
0.4	2.9	GO:0032280	symmetric synapse(GO:0032280)
0.4	2.4	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.4	8.0	GO:0030992	intraciliary transport particle B(GO:0030992)
0.4	8.3	GO:0005801	cis-Golgi network(GO:0005801)
0.4	2.0	GO:0002080	acrosomal membrane(GO:0002080)
0.4	2.3	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.4	1.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4	3.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.4	1.8	GO:0071565	nBAF complex(GO:0071565)
0.3	1.7	GO:0042824	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.3	43.2	GO:0016605	PML body(GO:0016605)
0.3	6.2	GO:0005922	connexon complex(GO:0005922)
0.3	23.5	GO:0005814	centriole(GO:0005814)
0.3	4.0	GO:0030008	TRAPP complex(GO:0030008)
0.3	3.5	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.3	3.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.3	23.7	GO:0034707	chloride channel complex(GO:0034707)
0.3	3.9	GO:0009925	basal plasma membrane(GO:0009925)
0.3	5.9	GO:0097546	ciliary base(GO:0097546)
0.3	36.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.3	1.9	GO:0030891	VCB complex(GO:0030891)
0.3	1.8	GO:0031088	platelet dense granule membrane(GO:0031088)
0.3	7.2	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.2	3.7	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.2	1.9	GO:0035686	sperm fibrous sheath(GO:0035686)
0.2	0.7	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2	2.6	GO:0097539	ciliary transition fiber(GO:0097539)
0.2	1.6	GO:0002116	semaphorin receptor complex(GO:0002116)
0.2	0.7	GO:0071438	invadopodium membrane(GO:0071438)
0.2	1.8	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2	5.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.2	11.0	GO:0036064	ciliary basal body(GO:0036064)
0.2	0.8	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2	0.6	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.2	10.9	GO:0005811	lipid particle(GO:0005811)
0.2	1.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	2.9	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.2	1.5	GO:0000137	Golgi cis cisterna(GO:0000137)
0.2	1.8	GO:0005915	zonula adherens(GO:0005915)
0.2	3.0	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.2	4.2	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.2	7.1	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2	1.4	GO:0000813	ESCRT I complex(GO:0000813)
0.2	2.6	GO:0001917	photoreceptor inner segment(GO:0001917)
0.1	8.9	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	9.5	GO:0031901	early endosome membrane(GO:0031901)
0.1	1.7	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.8	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	0.7	GO:0072487	MSL complex(GO:0072487)
0.1	329.8	GO:0031224	intrinsic component of membrane(GO:0031224)
0.1	0.2	GO:0035517	PR-DUB complex(GO:0035517)
0.0	0.0	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.2	GO:0042643	actomyosin, actin portion(GO:0042643)
0.0	0.4	GO:0000800	lateral element(GO:0000800)
0.0	0.5	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.1	GO:0005760	gamma DNA polymerase complex(GO:0005760)
0.0	0.4	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
24.7	98.7	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
21.9	153.3	GO:0030369	ICAM-3 receptor activity(GO:0030369)
19.2	57.7	GO:0045322	unmethylated CpG binding(GO:0045322)
17.1	51.3	GO:0004051	arachidonate 5-lipoxygenase activity(GO:0004051)
17.0	1018.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
16.7	150.2	GO:0043426	MRF binding(GO:0043426)
12.5	50.1	GO:0033897	ribonuclease T2 activity(GO:0033897)
12.1	460.5	GO:0042605	peptide antigen binding(GO:0042605)
11.7	58.6	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
10.4	83.4	GO:0032396	inhibitory MHC class I receptor activity(GO:0032396)
10.1	30.3	GO:0008859	exoribonuclease II activity(GO:0008859)
10.0	39.9	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
9.0	36.2	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
8.9	26.8	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
8.5	119.4	GO:0019864	IgG binding(GO:0019864)
8.1	40.4	GO:0042610	CD8 receptor binding(GO:0042610)
8.1	32.3	GO:0004341	gluconolactonase activity(GO:0004341)
7.7	23.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
7.6	22.9	GO:0004878	complement component C5a receptor activity(GO:0004878)
7.6	30.2	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
7.5	30.0	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
7.4	7.4	GO:0001851	complement component C3b binding(GO:0001851)
6.3	19.0	GO:0016154	thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
6.3	19.0	GO:0005011	macrophage colony-stimulating factor receptor activity(GO:0005011)
6.2	50.0	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
6.1	892.8	GO:0003823	antigen binding(GO:0003823)
6.0	54.2	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
6.0	18.0	GO:0042289	MHC class II protein binding(GO:0042289)
5.9	17.8	GO:0004912	interleukin-3 receptor activity(GO:0004912)
5.9	29.5	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
5.7	22.8	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
5.6	33.7	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
5.3	21.3	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
5.3	15.9	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
5.2	31.5	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
5.2	77.7	GO:0005344	oxygen transporter activity(GO:0005344)
5.2	31.0	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
5.1	15.4	GO:0033749	histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
5.1	20.5	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
4.9	24.3	GO:0004771	sterol esterase activity(GO:0004771)
4.8	14.3	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
4.7	28.4	GO:0030172	troponin C binding(GO:0030172)
4.7	14.1	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
4.7	14.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
4.6	37.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
4.5	22.7	GO:0032395	MHC class II receptor activity(GO:0032395)
4.4	17.7	GO:0004773	steryl-sulfatase activity(GO:0004773)
4.2	12.7	GO:0030350	iron-responsive element binding(GO:0030350)
4.2	21.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
4.2	12.6	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
4.2	20.9	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
4.1	20.6	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
4.0	63.5	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
3.8	11.5	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
3.8	22.6	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554)
3.7	18.6	GO:0004803	transposase activity(GO:0004803)
3.6	10.9	GO:0004336	galactosylceramidase activity(GO:0004336)
3.6	47.2	GO:0036374	glutathione hydrolase activity(GO:0036374)
3.6	21.8	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
3.6	43.0	GO:0008430	selenium binding(GO:0008430)
3.6	28.6	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
3.5	42.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
3.5	24.3	GO:0004797	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
3.5	3.5	GO:0047787	delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
3.4	17.2	GO:0043208	glycosphingolipid binding(GO:0043208)
3.4	20.2	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
3.4	30.2	GO:0004875	complement receptor activity(GO:0004875)
3.3	10.0	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
3.2	9.7	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
3.2	32.4	GO:0008131	primary amine oxidase activity(GO:0008131)
3.2	9.6	GO:0016497	substance K receptor activity(GO:0016497)
3.1	18.7	GO:0004882	androgen receptor activity(GO:0004882)
3.1	12.3	GO:0032408	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
3.1	12.2	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
3.0	6.1	GO:0005151	interleukin-1, Type II receptor binding(GO:0005151)
3.0	12.1	GO:0031716	calcitonin receptor binding(GO:0031716)
3.0	6.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
2.9	14.6	GO:0042903	tubulin deacetylase activity(GO:0042903)
2.9	11.6	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.9	40.7	GO:0031419	cobalamin binding(GO:0031419)
2.9	11.5	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
2.8	14.2	GO:0004522	ribonuclease A activity(GO:0004522)
2.8	8.5	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
2.8	39.4	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.8	103.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
2.7	16.3	GO:0008420	CTD phosphatase activity(GO:0008420)
2.7	8.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
2.7	8.1	GO:0050405	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
2.7	8.1	GO:0001601	peptide YY receptor activity(GO:0001601)
2.7	2.7	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
2.6	7.8	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
2.6	2.6	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
2.5	7.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
2.5	10.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
2.5	15.0	GO:0071723	lipopeptide binding(GO:0071723)
2.5	19.8	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
2.5	14.7	GO:0008172	S-methyltransferase activity(GO:0008172)
2.4	7.3	GO:0016936	galactoside binding(GO:0016936)
2.4	26.6	GO:0051525	NFAT protein binding(GO:0051525)
2.4	7.2	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
2.4	14.4	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
2.4	12.0	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
2.4	14.3	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
2.4	4.8	GO:0016019	peptidoglycan receptor activity(GO:0016019)
2.4	21.4	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
2.4	16.6	GO:0032393	MHC class I receptor activity(GO:0032393)
2.4	7.1	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
2.3	9.4	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
2.3	7.0	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
2.3	9.3	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
2.3	11.6	GO:0042296	ISG15 transferase activity(GO:0042296)
2.3	6.9	GO:0035473	lipase binding(GO:0035473)
2.3	16.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
2.3	6.9	GO:0048030	disaccharide binding(GO:0048030)
2.3	6.9	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
2.3	6.9	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
2.3	6.9	GO:0070735	protein-glycine ligase activity(GO:0070735)
2.3	22.9	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
2.3	20.3	GO:0034235	GPI anchor binding(GO:0034235)
2.2	15.7	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
2.2	6.7	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
2.2	11.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
2.2	8.9	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
2.2	2.2	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
2.2	6.6	GO:0061609	fructose-1-phosphate aldolase activity(GO:0061609)
2.2	6.6	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
2.2	23.7	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
2.1	21.4	GO:0004957	prostaglandin E receptor activity(GO:0004957)
2.1	8.5	GO:0061714	folic acid receptor activity(GO:0061714)
2.1	10.4	GO:0004905	type I interferon receptor activity(GO:0004905)
2.1	18.5	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.0	79.3	GO:0071889	14-3-3 protein binding(GO:0071889)
2.0	8.1	GO:0042954	lipoprotein transporter activity(GO:0042954)
2.0	14.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
2.0	9.9	GO:0003796	lysozyme activity(GO:0003796)
2.0	5.9	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
2.0	15.8	GO:0098821	BMP receptor activity(GO:0098821)
2.0	7.8	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
1.9	5.8	GO:0004577	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
1.9	13.6	GO:0019863	IgE binding(GO:0019863)
1.9	5.8	GO:0047783	steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
1.9	21.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
1.9	5.7	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.9	20.8	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
1.9	7.5	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.9	5.6	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.8	7.4	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
1.8	12.9	GO:0001849	complement component C1q binding(GO:0001849)
1.8	7.3	GO:0005148	prolactin receptor binding(GO:0005148)
1.8	5.5	GO:0017129	triglyceride binding(GO:0017129)
1.8	27.0	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
1.8	1.8	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
1.8	5.4	GO:0004421	hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.8	1.8	GO:0004031	aldehyde oxidase activity(GO:0004031)
1.8	56.7	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.8	5.3	GO:0008969	phosphohistidine phosphatase activity(GO:0008969)
1.8	5.3	GO:0015204	urea transmembrane transporter activity(GO:0015204)
1.8	7.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
1.8	24.6	GO:0042609	CD4 receptor binding(GO:0042609)
1.8	35.1	GO:0042288	MHC class I protein binding(GO:0042288)
1.7	7.0	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
1.7	7.0	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.7	43.6	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
1.7	8.6	GO:0030348	syntaxin-3 binding(GO:0030348)
1.7	8.6	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.7	17.1	GO:0001042	RNA polymerase I core binding(GO:0001042)
1.7	15.3	GO:0000403	Y-form DNA binding(GO:0000403)
1.7	5.1	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
1.7	5.1	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.7	5.1	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
1.7	15.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
1.7	10.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
1.7	6.7	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
1.7	30.0	GO:0004089	carbonate dehydratase activity(GO:0004089)
1.7	11.6	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.7	371.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.6	6.6	GO:0061656	SUMO conjugating enzyme activity(GO:0061656)
1.6	1.6	GO:0046978	TAP binding(GO:0046977) TAP1 binding(GO:0046978)
1.6	8.2	GO:0004368	glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
1.6	9.8	GO:0004035	alkaline phosphatase activity(GO:0004035)
1.6	6.4	GO:0004992	platelet activating factor receptor activity(GO:0004992)
1.6	3.2	GO:0070095	fructose-6-phosphate binding(GO:0070095)
1.6	12.7	GO:0097642	calcitonin family receptor activity(GO:0097642)
1.6	29.9	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.6	11.0	GO:0050294	steroid sulfotransferase activity(GO:0050294)
1.6	17.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
1.6	14.0	GO:0048019	receptor antagonist activity(GO:0048019)
1.6	6.2	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
1.6	4.7	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
1.6	4.7	GO:0003943	N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
1.5	21.7	GO:0045159	myosin II binding(GO:0045159)
1.5	24.8	GO:0003680	AT DNA binding(GO:0003680)
1.5	7.7	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.5	4.6	GO:0070573	metallodipeptidase activity(GO:0070573)
1.5	7.6	GO:0050436	microfibril binding(GO:0050436)
1.5	7.6	GO:0001594	trace-amine receptor activity(GO:0001594)
1.5	4.5	GO:0005173	stem cell factor receptor binding(GO:0005173)
1.5	8.9	GO:0005134	interleukin-2 receptor binding(GO:0005134)
1.5	4.5	GO:1904928	coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
1.5	14.9	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
1.5	13.2	GO:0004565	beta-galactosidase activity(GO:0004565)
1.5	10.2	GO:0044547	DNA topoisomerase binding(GO:0044547)
1.4	11.6	GO:0004126	cytidine deaminase activity(GO:0004126)
1.4	10.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
1.4	8.4	GO:0022821	calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
1.4	19.4	GO:0004559	alpha-mannosidase activity(GO:0004559)
1.4	5.5	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
1.4	2.8	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
1.4	4.1	GO:0004961	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.4	8.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
1.4	5.5	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
1.4	4.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
1.4	17.6	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
1.3	9.4	GO:0030911	TPR domain binding(GO:0030911)
1.3	6.7	GO:0003909	DNA ligase activity(GO:0003909)
1.3	25.3	GO:0038191	neuropilin binding(GO:0038191)
1.3	5.3	GO:0045569	TRAIL binding(GO:0045569)
1.3	38.2	GO:0042169	SH2 domain binding(GO:0042169)
1.3	3.9	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
1.3	10.4	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
1.3	15.6	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.3	3.9	GO:0033142	progesterone receptor binding(GO:0033142)
1.3	5.1	GO:0001632	leukotriene B4 receptor activity(GO:0001632)
1.3	7.7	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
1.3	6.4	GO:0016160	amylase activity(GO:0016160)
1.3	5.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
1.3	5.0	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.3	10.0	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
1.2	9.9	GO:0004000	adenosine deaminase activity(GO:0004000)
1.2	100.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.2	4.9	GO:0004079	biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
1.2	18.5	GO:0031701	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
1.2	9.8	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.2	3.6	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
1.2	3.6	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.2	10.8	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
1.2	8.4	GO:0030368	interleukin-17 receptor activity(GO:0030368)
1.2	6.0	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
1.2	30.6	GO:0071837	HMG box domain binding(GO:0071837)
1.2	2.4	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
1.2	4.7	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
1.2	3.5	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.2	4.7	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
1.2	39.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.1	4.6	GO:0002046	opsin binding(GO:0002046)
1.1	2.3	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
1.1	5.7	GO:1990254	keratin filament binding(GO:1990254)
1.1	6.8	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
1.1	3.4	GO:0004157	dihydropyrimidinase activity(GO:0004157)
1.1	59.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.1	7.8	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.1	10.0	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.1	3.3	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.1	4.4	GO:0047298	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
1.1	5.5	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.1	6.6	GO:0019865	immunoglobulin binding(GO:0019865)
1.1	5.5	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.1	5.5	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
1.1	3.3	GO:0016833	oxo-acid-lyase activity(GO:0016833)
1.1	19.7	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.1	10.9	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
1.1	31.6	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
1.1	1.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
1.1	3.2	GO:0002113	interleukin-33 binding(GO:0002113)
1.1	25.5	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
1.1	8.4	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
1.0	7.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
1.0	3.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
1.0	6.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
1.0	2.1	GO:0004995	tachykinin receptor activity(GO:0004995)
1.0	1.0	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.0	42.3	GO:0030332	cyclin binding(GO:0030332)
1.0	17.1	GO:0042809	vitamin D receptor binding(GO:0042809)
1.0	59.4	GO:0004180	carboxypeptidase activity(GO:0004180)
1.0	10.9	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
1.0	4.0	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
1.0	3.0	GO:0008431	vitamin E binding(GO:0008431)
1.0	3.0	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.0	6.9	GO:0001515	opioid peptide activity(GO:0001515)
1.0	3.9	GO:0015307	drug:proton antiporter activity(GO:0015307)
1.0	3.9	GO:0008422	beta-glucosidase activity(GO:0008422)
1.0	5.9	GO:0070728	leucine binding(GO:0070728)
1.0	3.9	GO:0009378	four-way junction helicase activity(GO:0009378)
1.0	3.9	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
1.0	10.6	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
1.0	2.9	GO:0004630	phospholipase D activity(GO:0004630)
0.9	26.5	GO:0071949	FAD binding(GO:0071949)
0.9	3.7	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.9	2.8	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.9	6.4	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.9	6.4	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.9	8.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.9	1.8	GO:0032427	GBD domain binding(GO:0032427)
0.9	18.0	GO:0050811	GABA receptor binding(GO:0050811)
0.9	2.7	GO:0005042	netrin receptor activity(GO:0005042)
0.9	4.4	GO:0008410	CoA-transferase activity(GO:0008410)
0.9	4.4	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.9	18.6	GO:0019992	diacylglycerol binding(GO:0019992)
0.9	3.5	GO:0030492	hemoglobin binding(GO:0030492)
0.9	13.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.9	12.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.9	17.5	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.9	4.4	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.9	7.8	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.9	2.6	GO:0030290	sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.9	13.7	GO:0051787	misfolded protein binding(GO:0051787)
0.9	12.8	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.8	6.8	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.8	2.5	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.8	9.3	GO:0050700	CARD domain binding(GO:0050700)
0.8	5.8	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.8	4.9	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.8	4.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8	2.5	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.8	3.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.8	6.5	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.8	8.9	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.8	278.0	GO:0005096	GTPase activator activity(GO:0005096)
0.8	9.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.8	6.3	GO:0031433	telethonin binding(GO:0031433)
0.8	2.4	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.8	3.1	GO:0001031	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.8	3.1	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.8	15.7	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.8	14.0	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.8	2.3	GO:0031862	prostanoid receptor binding(GO:0031862)
0.8	15.3	GO:0005522	profilin binding(GO:0005522)
0.8	8.4	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.8	6.9	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.8	6.1	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.8	7.5	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.8	15.0	GO:0042056	chemoattractant activity(GO:0042056)
0.7	9.0	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.7	72.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.7	2.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.7	5.2	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.7	1.5	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.7	7.4	GO:0070569	uridylyltransferase activity(GO:0070569)
0.7	3.7	GO:0016841	ammonia-lyase activity(GO:0016841)
0.7	2.9	GO:0002114	interleukin-33 receptor activity(GO:0002114)
0.7	15.1	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7	8.6	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.7	4.3	GO:0042608	T cell receptor binding(GO:0042608)
0.7	8.6	GO:0008097	5S rRNA binding(GO:0008097)
0.7	24.7	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.7	9.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.7	43.7	GO:0070412	R-SMAD binding(GO:0070412)
0.7	7.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.7	4.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.7	3.5	GO:0017018	myosin phosphatase activity(GO:0017018)
0.7	3.5	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.7	6.2	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.7	4.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.7	8.8	GO:0008199	ferric iron binding(GO:0008199)
0.7	8.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.7	12.8	GO:0048156	tau protein binding(GO:0048156)
0.7	4.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.7	18.1	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.7	5.3	GO:0000405	bubble DNA binding(GO:0000405)
0.7	7.9	GO:1990239	steroid hormone binding(GO:1990239)
0.7	12.5	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.7	2.0	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.7	2.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.6	3.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.6	10.3	GO:0045125	bioactive lipid receptor activity(GO:0045125)
0.6	16.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.6	3.8	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.6	1.9	GO:0052854	(S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.6	120.0	GO:0005057	receptor signaling protein activity(GO:0005057)
0.6	2.5	GO:0043237	laminin-1 binding(GO:0043237)
0.6	17.5	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.6	2.5	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.6	7.4	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.6	2.5	GO:0099609	microtubule lateral binding(GO:0099609)
0.6	6.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.6	3.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.6	7.3	GO:0051434	BH3 domain binding(GO:0051434)
0.6	3.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.6	9.1	GO:0070300	phosphatidic acid binding(GO:0070300)
0.6	12.7	GO:0031005	filamin binding(GO:0031005)
0.6	4.2	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.6	11.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.6	13.0	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.6	3.5	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6	9.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.6	6.9	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.6	2.9	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.6	1.7	GO:0004967	glucagon receptor activity(GO:0004967)
0.6	2.3	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056)
0.6	1.7	GO:0031711	angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.6	2.2	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.6	3.9	GO:0008417	fucosyltransferase activity(GO:0008417)
0.6	2.2	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.6	5.0	GO:0004969	histamine receptor activity(GO:0004969)
0.6	10.5	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.6	1.1	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.5	2.7	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.5	11.3	GO:0001223	transcription coactivator binding(GO:0001223)
0.5	26.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.5	12.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.5	61.1	GO:0005179	hormone activity(GO:0005179)
0.5	10.6	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.5	12.7	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.5	2.6	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.5	1.6	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.5	2.1	GO:0004966	galanin receptor activity(GO:0004966)
0.5	6.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.5	1.5	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.5	1.5	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.5	4.1	GO:0015232	heme transporter activity(GO:0015232)
0.5	29.4	GO:0043621	protein self-association(GO:0043621)
0.5	1.5	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.5	11.5	GO:0050321	tau-protein kinase activity(GO:0050321)
0.5	14.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.5	6.9	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.5	9.3	GO:0005272	sodium channel activity(GO:0005272)
0.5	1.5	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.5	5.3	GO:0015643	toxic substance binding(GO:0015643)
0.5	1.9	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.5	1.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.5	6.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.5	2.8	GO:0004359	glutaminase activity(GO:0004359)
0.5	11.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.5	3.2	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.5	7.4	GO:0016594	glycine binding(GO:0016594)
0.5	8.3	GO:0016849	phosphorus-oxygen lyase activity(GO:0016849)
0.5	6.8	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.4	1.8	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.4	2.6	GO:0039552	RIG-I binding(GO:0039552)
0.4	4.8	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.4	11.4	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.4	2.6	GO:0004111	creatine kinase activity(GO:0004111)
0.4	0.9	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.4	1.3	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4	2.1	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.4	5.5	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.4	8.1	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.4	1.7	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.4	1.7	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
0.4	4.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.4	2.5	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.4	5.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4	0.8	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.4	10.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4	3.6	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4	1.6	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.4	1.6	GO:0042015	interleukin-20 binding(GO:0042015)
0.4	3.1	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.4	0.4	GO:1902271	D3 vitamins binding(GO:1902271)
0.4	5.1	GO:0070700	BMP receptor binding(GO:0070700)
0.4	1.9	GO:0031996	thioesterase binding(GO:0031996)
0.4	7.7	GO:0043014	alpha-tubulin binding(GO:0043014)
0.4	1.1	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.4	2.6	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.4	4.5	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.4	6.3	GO:0001614	G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4	24.4	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.4	4.0	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.4	20.2	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.4	4.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.4	2.5	GO:0032027	myosin light chain binding(GO:0032027)
0.4	0.7	GO:0004040	amidase activity(GO:0004040)
0.4	1.1	GO:0042019	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.4	14.2	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.4	58.9	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3	1.7	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3	30.3	GO:0019210	kinase inhibitor activity(GO:0019210)
0.3	3.7	GO:0030280	structural constituent of epidermis(GO:0030280)
0.3	33.9	GO:0004984	olfactory receptor activity(GO:0004984)
0.3	5.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.3	1.7	GO:0070097	delta-catenin binding(GO:0070097)
0.3	4.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.3	5.4	GO:0000150	recombinase activity(GO:0000150)
0.3	0.7	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.3	1.7	GO:0030553	cGMP binding(GO:0030553)
0.3	2.3	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.3	6.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.3	7.9	GO:0032451	demethylase activity(GO:0032451)
0.3	5.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.3	11.3	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3	1.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.3	3.4	GO:0048018	receptor agonist activity(GO:0048018)
0.3	7.7	GO:0001540	beta-amyloid binding(GO:0001540)
0.3	1.2	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.3	4.5	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3	0.9	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.3	0.6	GO:0022824	transmitter-gated ion channel activity(GO:0022824) transmitter-gated channel activity(GO:0022835)
0.3	1.4	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.3	2.3	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.3	354.3	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.3	13.1	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.3	1.1	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.3	4.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3	0.5	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.3	5.6	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.3	18.9	GO:0035004	phosphatidylinositol 3-kinase activity(GO:0035004)
0.3	1.8	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3	1.3	GO:0004370	glycerol kinase activity(GO:0004370)
0.3	4.5	GO:0016018	cyclosporin A binding(GO:0016018)
0.2	0.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2	1.2	GO:0004447	iodide peroxidase activity(GO:0004447)
0.2	22.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	0.7	GO:0034736	sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2	2.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2	1.4	GO:0031013	troponin I binding(GO:0031013)
0.2	0.7	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.2	35.4	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.2	3.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.2	0.7	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.2	0.7	GO:0015616	DNA translocase activity(GO:0015616)
0.2	0.7	GO:0004998	transferrin receptor activity(GO:0004998)
0.2	0.4	GO:0004743	pyruvate kinase activity(GO:0004743)
0.2	4.0	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.2	1.8	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2	0.8	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.2	1.2	GO:0017040	ceramidase activity(GO:0017040)
0.2	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	26.3	GO:0005516	calmodulin binding(GO:0005516)
0.2	3.7	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.2	0.8	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2	0.6	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.2	1.1	GO:0004046	aminoacylase activity(GO:0004046)
0.2	0.6	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.2	0.6	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.2	9.7	GO:0005254	chloride channel activity(GO:0005254)
0.2	0.9	GO:0008158	hedgehog receptor activity(GO:0008158)
0.2	2.7	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.2	1.2	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.2	2.3	GO:0019841	retinol binding(GO:0019841)
0.2	1.6	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.2	0.7	GO:0097322	7SK snRNA binding(GO:0097322)
0.2	0.5	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.2	2.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.2	0.3	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.2	4.6	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	2.0	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	1.0	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	1.9	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.1	1.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	2.3	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	0.4	GO:0004348	glucosylceramidase activity(GO:0004348)
0.1	0.8	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	4.8	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	3.0	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.2	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1	0.5	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.1	0.5	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.2	GO:0070888	E-box binding(GO:0070888)
0.1	9.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.4	GO:0008480	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1	1.7	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	0.3	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	1.1	GO:0099589	serotonin receptor activity(GO:0099589)
0.1	0.5	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.4	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.1	3.9	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	0.7	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	2.5	GO:0022829	wide pore channel activity(GO:0022829)
0.1	0.4	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.1	0.5	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1	0.8	GO:0046965	retinoid X receptor binding(GO:0046965)
0.1	0.4	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.1	1.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.1	0.7	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.4	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1	1.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	0.7	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	0.4	GO:0042834	peptidoglycan binding(GO:0042834)
0.1	1.3	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.3	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.2	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.1	0.3	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	3.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.2	GO:0015350	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0	0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	1.1	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	2.8	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0	0.4	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	1.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.3	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	0.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.1	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.0	344.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
5.2	15.5	PID S1P S1P2 PATHWAY	S1P2 pathway
4.4	13.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
3.7	324.3	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
3.5	10.6	PID S1P S1P4 PATHWAY	S1P4 pathway
3.4	325.8	PID IL4 2PATHWAY	IL4-mediated signaling events
3.3	6.6	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
2.6	23.7	PID IL27 PATHWAY	IL27-mediated signaling events
2.4	29.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
2.4	7.1	ST STAT3 PATHWAY	STAT3 Pathway
2.2	32.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
2.1	51.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
2.0	27.5	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
1.8	29.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.8	77.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
1.7	106.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
1.7	6.9	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
1.7	17.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
1.7	13.6	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
1.6	6.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
1.6	1.6	ST GAQ PATHWAY	G alpha q Pathway
1.5	47.5	PID IL1 PATHWAY	IL1-mediated signaling events
1.5	3.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
1.5	10.4	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
1.5	37.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
1.5	7.4	ST JAK STAT PATHWAY	Jak-STAT Pathway
1.5	56.6	PID BCR 5PATHWAY	BCR signaling pathway
1.4	15.8	PID ALK1 PATHWAY	ALK1 signaling events
1.4	12.8	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
1.4	19.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
1.4	9.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
1.4	73.0	PID IL12 2PATHWAY	IL12-mediated signaling events
1.3	12.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
1.2	41.6	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
1.2	82.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
1.0	51.4	PID ARF6 PATHWAY	Arf6 signaling events
1.0	44.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
1.0	13.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
1.0	35.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.9	20.8	PID IFNG PATHWAY	IFN-gamma pathway
0.9	17.1	PID EPHA FWDPATHWAY	EPHA forward signaling
0.9	2.7	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.9	14.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.8	149.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.8	15.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.8	4.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.8	26.7	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.8	8.1	PID EPO PATHWAY	EPO signaling pathway
0.8	19.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.7	14.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.7	8.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.7	12.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.7	16.2	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.7	16.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.7	3.3	NABA COLLAGENS	Genes encoding collagen proteins
0.6	5.8	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.6	3.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6	15.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.6	2.4	PID IL23 PATHWAY	IL23-mediated signaling events
0.6	25.5	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.6	23.8	PID P53 REGULATION PATHWAY	p53 pathway
0.6	17.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5	5.4	PID CONE PATHWAY	Visual signal transduction: Cones
0.5	35.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.5	132.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5	8.0	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.5	32.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.5	33.0	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.5	1.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.5	29.0	PID RAC1 PATHWAY	RAC1 signaling pathway
0.5	12.6	ST GA13 PATHWAY	G alpha 13 Pathway
0.5	7.5	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.5	2.8	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5	25.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.4	2.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.4	8.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.4	14.4	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.4	0.8	PID IL5 PATHWAY	IL5-mediated signaling events
0.4	3.5	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.4	6.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.4	3.8	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.4	22.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.4	7.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.4	28.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.4	4.6	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.3	18.7	PID MTOR 4PATHWAY	mTOR signaling pathway
0.3	2.9	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.3	8.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.3	1.7	PID CD40 PATHWAY	CD40/CD40L signaling
0.3	9.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.3	1.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.3	31.8	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.3	12.6	PID LKB1 PATHWAY	LKB1 signaling events
0.3	2.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.3	4.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.2	20.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.2	14.8	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	1.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	2.7	PID RAS PATHWAY	Regulation of Ras family activation
0.2	10.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	1.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2	4.9	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2	2.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.2	2.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.2	5.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.2	7.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	7.9	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.2	0.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	43.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	2.2	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	3.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	4.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	5.7	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	1.9	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	5.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	3.0	PID CDC42 PATHWAY	CDC42 signaling events
0.1	0.9	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.9	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.9	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	1.2	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.3	384.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
11.2	123.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
10.5	73.7	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
6.8	13.6	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
5.5	27.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
5.3	457.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
3.6	7.2	REACTOME SIGNALING BY NOTCH	Genes involved in Signaling by NOTCH
3.2	6.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
3.2	6.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
3.1	55.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
2.7	53.8	REACTOME DEFENSINS	Genes involved in Defensins
2.6	49.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.6	36.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
2.4	35.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
2.4	58.9	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
2.2	10.9	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
2.1	33.0	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
2.0	26.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
1.9	28.0	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
1.8	24.0	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
1.8	3.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.8	42.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.7	5.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
1.6	70.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
1.6	3.3	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
1.6	4.7	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.6	20.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
1.5	7.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.5	6.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
1.5	48.8	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
1.5	26.4	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
1.5	45.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
1.5	8.7	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
1.4	5.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.4	15.8	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
1.4	32.9	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
1.4	14.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
1.4	63.7	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
1.3	80.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
1.3	21.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
1.3	29.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
1.3	55.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
1.3	27.8	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
1.3	33.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
1.2	12.5	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
1.1	29.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
1.1	9.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
1.1	9.9	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
1.1	10.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.1	18.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
1.1	8.6	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.1	22.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
1.0	25.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
1.0	59.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
1.0	21.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
1.0	7.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
1.0	3.0	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
1.0	33.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.9	5.7	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.9	4.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.9	4.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.9	3.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.9	16.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.9	4.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.9	34.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.9	14.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.9	38.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.9	21.4	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.8	24.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.8	31.1	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.8	8.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.8	40.0	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.8	7.9	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.8	73.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.8	11.0	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.8	6.3	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.8	4.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.8	9.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.7	11.0	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.7	11.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.7	32.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.7	9.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.7	15.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.7	305.9	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.7	7.5	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.7	6.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.7	10.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.7	16.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.7	28.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.6	36.3	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.6	90.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.6	4.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.6	3.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.6	11.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.6	13.0	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.6	5.9	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.6	15.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.5	6.0	REACTOME OPSINS	Genes involved in Opsins
0.5	20.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.5	3.6	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.5	92.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.5	10.6	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.5	65.3	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.5	3.0	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.5	10.7	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.5	12.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.5	9.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.5	13.2	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.4	31.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.4	4.8	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.4	21.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.4	8.3	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.4	13.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.4	5.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.4	9.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.4	5.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.4	29.8	REACTOME PI3K EVENTS IN ERBB2 SIGNALING	Genes involved in PI3K events in ERBB2 signaling
0.4	2.6	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.4	7.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.4	31.3	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.3	5.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	6.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.3	10.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.3	1.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.3	21.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.3	2.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.3	1.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.3	4.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3	9.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3	13.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3	5.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.3	9.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	2.8	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.2	5.4	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.2	8.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.2	1.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2	2.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.2	1.5	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.2	5.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	1.8	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.2	1.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.2	3.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2	3.8	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.2	3.8	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2	0.7	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.2	4.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.2	2.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2	1.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	1.9	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	0.8	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	3.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	2.3	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	8.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	14.0	REACTOME GPCR DOWNSTREAM SIGNALING	Genes involved in GPCR downstream signaling
0.1	0.6	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.4	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	4.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	6.4	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.1	0.7	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	3.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	0.6	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.1	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.1	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	3.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.5	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.8	REACTOME NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Neurotransmitter Release Cycle

Results for SMAD1

Z-value: 3.16

Motif logo

Transcription factors associated with SMAD1

Activity-expression correlation:

Activity profile of SMAD1 motif

Sorted Z-values of SMAD1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: