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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SOX18

Z-value: 0.66

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Transcription factors associated with SOX18

Gene Symbol Gene ID Gene Info
SOX18
ENSG00000203883.7 SOX18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX18hg38_v1_chr20_-_64049631_640496460.018.5e-01Click!

Activity profile of SOX18 motif

Sorted Z-values of SOX18 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX18

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_133746385 13.21 ENST00000482271.5
ENST00000402696.9
TF
transferrin
chr1_-_156248013 7.38 ENST00000368270.2
PAQR6
progestin and adipoQ receptor family member 6
chr1_-_156248084 7.35 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
PAQR6
progestin and adipoQ receptor family member 6
chr11_-_117876719 6.69 ENST00000529335.6
ENST00000260282.8
FXYD6
FXYD domain containing ion transport regulator 6
chr1_-_156248038 6.57 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
PAQR6
progestin and adipoQ receptor family member 6
chr11_-_117876892 5.66 ENST00000539526.5
FXYD6
FXYD domain containing ion transport regulator 6
chr3_+_111998739 5.27 ENST00000393917.6
ENST00000273368.8
TAGLN3
transgelin 3
chr5_-_147081428 5.22 ENST00000394413.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr5_-_147081462 4.82 ENST00000508267.5
ENST00000504198.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr1_-_230745574 4.58 ENST00000681269.1
AGT
angiotensinogen
chr4_-_173399102 4.49 ENST00000296506.8
SCRG1
stimulator of chondrogenesis 1
chr11_+_71527267 4.34 ENST00000398536.6
KRTAP5-7
keratin associated protein 5-7
chr6_-_152168291 4.20 ENST00000354674.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr6_-_152168349 4.16 ENST00000539504.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr3_+_111998915 4.05 ENST00000478951.6
TAGLN3
transgelin 3
chr3_+_124384513 3.94 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
KALRN
kalirin RhoGEF kinase
chr11_-_5227063 3.81 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
HBB
hemoglobin subunit beta
chr5_-_137499293 3.77 ENST00000510689.5
ENST00000394945.6
SPOCK1
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
chr3_-_121660892 3.66 ENST00000428394.6
ENST00000314583.8
HCLS1
hematopoietic cell-specific Lyn substrate 1
chrX_-_154805386 3.64 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
MPP1
membrane palmitoylated protein 1
chr4_-_86101922 3.56 ENST00000472236.5
ENST00000641881.1
MAPK10
mitogen-activated protein kinase 10
chr13_-_46182136 3.46 ENST00000323076.7
LCP1
lymphocyte cytosolic protein 1
chr13_-_46142834 3.45 ENST00000674665.1
LCP1
lymphocyte cytosolic protein 1
chr1_-_182391783 3.39 ENST00000331872.11
ENST00000339526.8
GLUL
glutamate-ammonia ligase
chr6_-_111793871 3.27 ENST00000368667.6
FYN
FYN proto-oncogene, Src family tyrosine kinase
chr3_+_124384757 3.26 ENST00000684374.1
KALRN
kalirin RhoGEF kinase
chr11_+_5689780 3.22 ENST00000379965.8
ENST00000454828.5
TRIM22
tripartite motif containing 22
chr4_+_153466324 3.18 ENST00000409663.7
ENST00000409959.8
TMEM131L
transmembrane 131 like
chr10_-_125816596 3.16 ENST00000368786.5
UROS
uroporphyrinogen III synthase
chr8_-_85341659 3.13 ENST00000522389.5
CA1
carbonic anhydrase 1
chr8_-_85341705 3.11 ENST00000517618.5
CA1
carbonic anhydrase 1
chr12_-_663572 3.10 ENST00000662884.1
NINJ2
ninjurin 2
chr11_-_117876612 3.10 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr1_-_182391363 3.08 ENST00000417584.6
GLUL
glutamate-ammonia ligase
chr5_-_142644201 2.95 ENST00000394496.2
ENST00000610990.4
FGF1
fibroblast growth factor 1
chr6_-_33418093 2.60 ENST00000488034.6
CUTA
cutA divalent cation tolerance homolog
chr16_-_15643024 2.55 ENST00000540441.6
MARF1
meiosis regulator and mRNA stability factor 1
chr4_+_69096494 2.47 ENST00000508661.5
ENST00000622664.1
UGT2B7
UDP glucuronosyltransferase family 2 member B7
chr6_-_33418077 2.44 ENST00000488478.5
CUTA
cutA divalent cation tolerance homolog
chr5_-_74640649 2.42 ENST00000537006.1
ENC1
ectodermal-neural cortex 1
chr17_-_75855204 2.34 ENST00000589642.5
ENST00000593002.1
ENST00000590221.5
ENST00000587374.5
ENST00000585462.5
ENST00000254806.8
ENST00000433525.6
ENST00000626827.2
WBP2
WW domain binding protein 2
chr6_-_33417878 2.32 ENST00000440279.7
ENST00000607266.5
CUTA
cutA divalent cation tolerance homolog
chr11_-_31804067 2.29 ENST00000639548.1
ENST00000640125.1
ENST00000481563.6
ENST00000639079.1
ENST00000638762.1
ENST00000638346.1
PAX6
paired box 6
chr12_+_25052512 2.27 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr5_+_157180816 2.22 ENST00000422843.8
ITK
IL2 inducible T cell kinase
chr6_-_33418125 2.19 ENST00000492510.1
ENST00000374500.10
CUTA
cutA divalent cation tolerance homolog
chr14_-_20802836 2.16 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
RNASE1
ribonuclease A family member 1, pancreatic
chr11_-_134253248 2.11 ENST00000392595.6
ENST00000352327.5
ENST00000341541.8
ENST00000392594.7
THYN1
thymocyte nuclear protein 1
chr4_+_69096467 2.04 ENST00000305231.12
UGT2B7
UDP glucuronosyltransferase family 2 member B7
chr6_-_33418046 2.02 ENST00000494751.5
ENST00000374496.3
CUTA
cutA divalent cation tolerance homolog
chr12_-_110502065 2.02 ENST00000447578.6
ENST00000546588.1
ENST00000360579.11
ENST00000549578.6
ENST00000549970.5
VPS29
VPS29 retromer complex component
chr16_-_28356654 1.91 ENST00000533640.5
NPIPB6
nuclear pore complex interacting protein family member B6
chr4_-_144019287 1.89 ENST00000638448.1
ENST00000513128.5
ENST00000506516.6
ENST00000429670.3
ENST00000502664.6
GYPB
glycophorin B (MNS blood group)
chr1_+_99850348 1.80 ENST00000361915.8
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr2_+_1414382 1.80 ENST00000423320.5
ENST00000346956.7
ENST00000382198.5
TPO
thyroid peroxidase
chr6_-_26234978 1.79 ENST00000244534.7
H1-3
H1.3 linker histone, cluster member
chr19_+_44072142 1.75 ENST00000421176.4
ZNF284
zinc finger protein 284
chr13_-_45418337 1.73 ENST00000519676.6
ENST00000519547.5
SLC25A30
solute carrier family 25 member 30
chr13_+_111153735 1.72 ENST00000375736.8
ARHGEF7
Rho guanine nucleotide exchange factor 7
chr18_+_35041387 1.70 ENST00000538170.6
ENST00000300249.10
ENST00000588910.5
MAPRE2
microtubule associated protein RP/EB family member 2
chr13_-_45418406 1.62 ENST00000539591.5
ENST00000522438.1
SLC25A30
solute carrier family 25 member 30
chr7_-_79453544 1.60 ENST00000419488.5
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_76023489 1.54 ENST00000306602.3
CXCL10
C-X-C motif chemokine ligand 10
chr1_+_209756032 1.52 ENST00000400959.7
ENST00000367025.8
TRAF3IP3
TRAF3 interacting protein 3
chr11_-_118176576 1.52 ENST00000278947.6
SCN2B
sodium voltage-gated channel beta subunit 2
chr11_+_113387773 1.51 ENST00000303941.4
ANKK1
ankyrin repeat and kinase domain containing 1
chr5_-_801145 1.49 ENST00000424784.3
ZDHHC11
zinc finger DHHC-type containing 11
chr4_+_153152163 1.44 ENST00000676423.1
ENST00000675745.1
ENST00000676348.1
ENST00000676408.1
ENST00000674874.1
ENST00000675315.1
ENST00000675518.1
TRIM2
ENSG00000288637.1
tripartite motif containing 2
novel protein
chr7_-_79453641 1.44 ENST00000354212.9
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_1484663 1.38 ENST00000446278.5
ENST00000469607.3
TPO
thyroid peroxidase
chr12_+_110502307 1.38 ENST00000409778.7
ENST00000409300.6
RAD9B
RAD9 checkpoint clamp component B
chr3_+_186613052 1.36 ENST00000411641.7
ENST00000273784.5
AHSG
alpha 2-HS glycoprotein
chr7_-_64982021 1.36 ENST00000610793.1
ENST00000620222.4
ZNF117
zinc finger protein 117
chr1_+_209756149 1.36 ENST00000367026.7
TRAF3IP3
TRAF3 interacting protein 3
chr11_+_74988896 1.36 ENST00000526068.1
ENST00000294064.9
ENST00000532963.1
ENST00000531619.1
ENST00000534628.1
NEU3
neuraminidase 3
chr6_-_128520358 1.35 ENST00000368215.7
ENST00000532331.5
ENST00000368213.9
ENST00000368207.7
ENST00000525459.1
ENST00000368226.9
ENST00000368210.7
PTPRK
protein tyrosine phosphatase receptor type K
chr12_-_11395556 1.34 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
PRB2
PRB1
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr5_-_79512794 1.29 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
HOMER1
homer scaffold protein 1
chr12_-_8066331 1.26 ENST00000546241.1
ENST00000307637.5
C3AR1
complement C3a receptor 1
chr17_+_70075317 1.26 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr14_+_35046238 1.24 ENST00000280987.9
FAM177A1
family with sequence similarity 177 member A1
chr2_+_209653171 1.23 ENST00000447185.5
MAP2
microtubule associated protein 2
chr9_-_96302104 1.21 ENST00000375262.4
ENST00000650386.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr1_+_99850485 1.17 ENST00000370165.7
ENST00000370163.7
ENST00000294724.8
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr6_-_26216673 1.16 ENST00000541790.3
H2BC8
H2B clustered histone 8
chr2_+_100974849 1.16 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr8_-_33567118 1.14 ENST00000256257.2
RNF122
ring finger protein 122
chr9_-_96302170 1.13 ENST00000375263.8
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr9_-_121050264 1.13 ENST00000223642.3
C5
complement C5
chr22_-_38084093 1.10 ENST00000681075.1
SLC16A8
solute carrier family 16 member 8
chr8_+_23288081 1.09 ENST00000265806.12
ENST00000519952.6
ENST00000518840.6
R3HCC1
R3H domain and coiled-coil containing 1
chr17_+_70075215 1.08 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr9_-_21351378 1.08 ENST00000380210.1
IFNA6
interferon alpha 6
chr10_+_68721012 1.08 ENST00000536391.5
ENST00000630771.2
CCAR1
cell division cycle and apoptosis regulator 1
chr6_-_75243770 1.06 ENST00000472311.6
ENST00000460985.1
ENST00000377978.3
ENST00000684430.1
ENST00000509698.6
COX7A2
cytochrome c oxidase subunit 7A2
chr19_+_8053000 1.05 ENST00000390669.7
CCL25
C-C motif chemokine ligand 25
chr16_+_33827140 1.05 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr22_-_38794111 1.05 ENST00000406622.5
ENST00000216068.9
ENST00000406199.3
SUN2
DNAL4
Sad1 and UNC84 domain containing 2
dynein axonemal light chain 4
chr1_+_179954740 1.02 ENST00000491495.2
ENST00000367607.8
CEP350
centrosomal protein 350
chr1_-_150765735 1.02 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
CTSS
cathepsin S
chr16_-_1611985 1.02 ENST00000426508.7
IFT140
intraflagellar transport 140
chrX_-_149505274 1.00 ENST00000428056.6
ENST00000340855.11
ENST00000370441.8
IDS
iduronate 2-sulfatase
chr7_-_79453459 1.00 ENST00000522391.3
ENST00000637441.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_134917872 0.98 ENST00000616356.4
ENST00000371806.4
FCN1
ficolin 1
chr7_-_6009019 0.95 ENST00000382321.5
ENST00000265849.12
PMS2
PMS1 homolog 2, mismatch repair system component
chr1_+_13303539 0.93 ENST00000437300.2
PRAMEF33
PRAME family member 33
chr8_+_24294044 0.93 ENST00000265769.9
ADAM28
ADAM metallopeptidase domain 28
chr15_+_43791842 0.91 ENST00000674451.1
ENST00000630046.2
SERF2
small EDRK-rich factor 2
chr11_+_13277639 0.89 ENST00000527998.5
ENST00000529388.6
ENST00000401424.6
ENST00000403510.8
ENST00000403290.6
ENST00000533520.5
ENST00000389707.8
ENST00000673817.1
ARNTL
aryl hydrocarbon receptor nuclear translocator like
chr9_-_71911183 0.86 ENST00000333421.7
ABHD17B
abhydrolase domain containing 17B, depalmitoylase
chr3_-_36993103 0.85 ENST00000322716.8
EPM2AIP1
EPM2A interacting protein 1
chr11_-_119095456 0.85 ENST00000530167.1
H2AX
H2A.X variant histone
chr22_-_19144641 0.85 ENST00000252137.11
ESS2
ess-2 splicing factor homolog
chr15_-_80252205 0.84 ENST00000560778.3
CTXND1
cortexin domain containing 1
chr4_-_39366342 0.82 ENST00000503784.1
ENST00000349703.7
ENST00000381897.5
RFC1
replication factor C subunit 1
chr3_+_186717348 0.80 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
KNG1
kininogen 1
chr6_+_26216928 0.79 ENST00000303910.4
H2AC8
H2A clustered histone 8
chr3_-_197573323 0.71 ENST00000358186.6
ENST00000431056.5
BDH1
3-hydroxybutyrate dehydrogenase 1
chr19_+_57231001 0.71 ENST00000415300.6
AURKC
aurora kinase C
chr18_-_5396265 0.70 ENST00000579951.2
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr15_-_79090760 0.69 ENST00000419573.7
ENST00000558480.7
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1
chr4_+_3441960 0.69 ENST00000382774.8
ENST00000511533.1
HGFAC
HGF activator
chr19_+_57231014 0.67 ENST00000302804.12
AURKC
aurora kinase C
chr12_+_69239560 0.66 ENST00000435070.7
CPSF6
cleavage and polyadenylation specific factor 6
chr13_-_98977975 0.66 ENST00000376460.5
DOCK9
dedicator of cytokinesis 9
chr15_+_78872809 0.65 ENST00000331268.9
MORF4L1
mortality factor 4 like 1
chr2_+_79025696 0.61 ENST00000272324.10
REG3G
regenerating family member 3 gamma
chr9_-_96302142 0.61 ENST00000648799.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr19_-_633500 0.60 ENST00000588649.7
POLRMT
RNA polymerase mitochondrial
chr12_-_262828 0.59 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
SLC6A13
solute carrier family 6 member 13
chr11_-_102705737 0.59 ENST00000260229.5
MMP27
matrix metallopeptidase 27
chr13_+_111115303 0.58 ENST00000646102.2
ENST00000449979.5
ARHGEF7
Rho guanine nucleotide exchange factor 7
chr19_+_8052752 0.57 ENST00000315626.6
ENST00000253451.9
CCL25
C-C motif chemokine ligand 25
chr8_-_21812320 0.57 ENST00000517328.5
GFRA2
GDNF family receptor alpha 2
chr19_-_14835252 0.57 ENST00000641666.1
ENST00000642030.1
ENST00000642000.1
OR7C1
olfactory receptor family 7 subfamily C member 1
chr17_+_27471999 0.57 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
KSR1
kinase suppressor of ras 1
chr6_-_31158073 0.57 ENST00000507751.5
ENST00000448162.6
ENST00000502557.5
ENST00000503420.5
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.5
ENST00000396263.6
ENST00000508683.5
ENST00000428174.1
ENST00000448141.6
ENST00000507829.5
ENST00000455279.6
ENST00000376266.9
CCHCR1
coiled-coil alpha-helical rod protein 1
chr2_+_79025678 0.56 ENST00000393897.6
REG3G
regenerating family member 3 gamma
chr5_+_141421064 0.56 ENST00000518882.2
PCDHGA11
protocadherin gamma subfamily A, 11
chr19_-_19733091 0.55 ENST00000344099.4
ZNF14
zinc finger protein 14
chr1_+_161153968 0.55 ENST00000368003.6
UFC1
ubiquitin-fold modifier conjugating enzyme 1
chr14_+_21868822 0.53 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chr5_+_141392616 0.53 ENST00000398604.3
PCDHGA8
protocadherin gamma subfamily A, 8
chr22_+_37282464 0.53 ENST00000402997.5
ENST00000405206.3
ENST00000248901.11
CYTH4
cytohesin 4
chr6_+_42915989 0.53 ENST00000441198.4
ENST00000446507.5
ENST00000616441.2
PTCRA
pre T cell antigen receptor alpha
chrX_+_47145240 0.52 ENST00000628161.2
ENST00000345781.10
RBM10
RNA binding motif protein 10
chr22_+_42553862 0.52 ENST00000340239.8
ENST00000327678.10
SERHL2
serine hydrolase like 2
chr5_-_56116946 0.51 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr7_+_157336961 0.51 ENST00000429029.6
DNAJB6
DnaJ heat shock protein family (Hsp40) member B6
chr19_+_48271327 0.51 ENST00000594024.5
ENST00000595408.5
ENST00000315849.5
ZNF114
zinc finger protein 114
chr12_-_95996302 0.50 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
HAL
histidine ammonia-lyase
chr4_+_7043315 0.50 ENST00000310074.8
ENST00000512388.1
TADA2B
transcriptional adaptor 2B
chr5_-_59356962 0.50 ENST00000405755.6
PDE4D
phosphodiesterase 4D
chr2_+_79025709 0.48 ENST00000409471.1
REG3G
regenerating family member 3 gamma
chrX_-_47145035 0.47 ENST00000276062.8
NDUFB11
NADH:ubiquinone oxidoreductase subunit B11
chr2_+_44275473 0.47 ENST00000260649.11
SLC3A1
solute carrier family 3 member 1
chr20_-_46364385 0.46 ENST00000243896.6
ENST00000543605.5
ENST00000372230.10
ENST00000317734.12
SLC35C2
solute carrier family 35 member C2
chr12_-_7936177 0.46 ENST00000544291.1
ENST00000075120.12
SLC2A3
solute carrier family 2 member 3
chr12_-_10435940 0.46 ENST00000381901.5
ENST00000381902.7
ENST00000539033.1
KLRC2
ENSG00000255641.1
killer cell lectin like receptor C2
novel protein
chr3_-_161105399 0.45 ENST00000652593.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr7_+_64903247 0.45 ENST00000476120.1
ZNF273
zinc finger protein 273
chr7_-_36724380 0.45 ENST00000617267.4
AOAH
acyloxyacyl hydrolase
chrX_-_111412162 0.44 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
DCX
doublecortin
chr11_+_61203512 0.44 ENST00000325558.11
PGA3
pepsinogen A3
chr5_-_41213505 0.42 ENST00000337836.10
ENST00000433294.1
C6
complement C6
chr12_+_15322529 0.41 ENST00000348962.7
PTPRO
protein tyrosine phosphatase receptor type O
chr7_-_6009072 0.41 ENST00000642456.1
ENST00000642292.1
ENST00000441476.6
PMS2
PMS1 homolog 2, mismatch repair system component
chr12_-_48570046 0.38 ENST00000301046.6
ENST00000549817.1
LALBA
lactalbumin alpha
chr2_+_201260510 0.38 ENST00000673742.1
CASP8
caspase 8
chr6_-_31897200 0.37 ENST00000395728.7
ENST00000375528.8
EHMT2
euchromatic histone lysine methyltransferase 2
chrX_+_30243715 0.37 ENST00000378981.8
ENST00000397550.6
MAGEB1
MAGE family member B1
chr14_-_21383989 0.36 ENST00000216297.7
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit
chr14_-_80231052 0.36 ENST00000557010.5
DIO2
iodothyronine deiodinase 2
chrX_-_47144680 0.36 ENST00000377811.4
NDUFB11
NADH:ubiquinone oxidoreductase subunit B11
chr19_+_54630497 0.35 ENST00000396332.8
ENST00000427581.6
LILRB1
leukocyte immunoglobulin like receptor B1
chrX_+_47145200 0.35 ENST00000377604.8
RBM10
RNA binding motif protein 10
chr16_-_4846196 0.34 ENST00000589389.5
GLYR1
glyoxylate reductase 1 homolog
chr2_+_240605417 0.34 ENST00000319838.10
ENST00000403859.1
GPR35
G protein-coupled receptor 35
chr5_+_32585549 0.33 ENST00000265073.9
ENST00000515355.5
ENST00000502897.5
ENST00000510442.1
SUB1
SUB1 regulator of transcription
chr5_+_141387698 0.33 ENST00000615384.1
ENST00000519479.2
PCDHGB4
protocadherin gamma subfamily B, 4
chr9_+_135702172 0.31 ENST00000487664.5
ENST00000371757.7
ENST00000628528.2
KCNT1
potassium sodium-activated channel subfamily T member 1
chr19_-_14835162 0.31 ENST00000322301.5
OR7A5
olfactory receptor family 7 subfamily A member 5
chr1_-_156859087 0.31 ENST00000368195.4
INSRR
insulin receptor related receptor
chrX_+_3066833 0.30 ENST00000359361.2
ARSF
arylsulfatase F
chr16_+_22519967 0.29 ENST00000621622.4
NPIPB5
nuclear pore complex interacting protein family member B5
chrX_-_15602150 0.29 ENST00000427411.2
ACE2
angiotensin I converting enzyme 2
chr17_+_28371656 0.28 ENST00000585482.6
SARM1
sterile alpha and TIR motif containing 1
chr19_+_40751179 0.28 ENST00000243563.8
ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr2_+_201260496 0.28 ENST00000323492.11
CASP8
caspase 8
chr14_-_106811131 0.28 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr14_+_22494810 0.27 ENST00000390493.1
TRAJ44
T cell receptor alpha joining 44
chr11_-_105023136 0.26 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
CASP5
caspase 5
chr6_+_29457155 0.26 ENST00000377133.6
ENST00000377136.5
OR2H1
olfactory receptor family 2 subfamily H member 1
chr2_+_3658193 0.25 ENST00000252505.4
ALLC
allantoicase
chr1_+_160081529 0.25 ENST00000368088.4
KCNJ9
potassium inwardly rectifying channel subfamily J member 9
chr13_-_28100556 0.25 ENST00000241453.12
FLT3
fms related receptor tyrosine kinase 3
chr6_+_42916046 0.24 ENST00000304672.6
PTCRA
pre T cell antigen receptor alpha
chr5_-_67196791 0.23 ENST00000256447.5
CD180
CD180 molecule
chr19_+_4402615 0.23 ENST00000301280.10
CHAF1A
chromatin assembly factor 1 subunit A
chr6_+_29111560 0.21 ENST00000377169.2
OR2J3
olfactory receptor family 2 subfamily J member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 13.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
1.6 6.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.5 4.6 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
1.3 3.8 GO:0030185 nitric oxide transport(GO:0030185)
0.9 9.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.8 7.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.8 3.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.6 4.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.6 1.7 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.4 10.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.4 4.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.4 2.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.4 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.4 3.2 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.3 6.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 1.0 GO:0034769 basement membrane disassembly(GO:0034769)
0.3 2.9 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.3 3.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.3 1.0 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3 1.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3 3.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 3.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 1.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.9 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 2.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 2.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.2 0.6 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 17.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 0.4 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2 2.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 3.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.2 3.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 1.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 0.5 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 0.7 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.2 0.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 2.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.5 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 4.9 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 6.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.9 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 2.0 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.4 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 1.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 1.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 1.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.4 GO:0051256 histone-serine phosphorylation(GO:0035404) mitotic spindle midzone assembly(GO:0051256)
0.1 3.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.4 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 1.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.3 GO:0043605 cellular amide catabolic process(GO:0043605)
0.1 1.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.5 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 2.7 GO:0007143 female meiotic division(GO:0007143)
0.1 1.2 GO:0051775 response to redox state(GO:0051775)
0.1 3.0 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 0.3 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.5 GO:0015811 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.1 1.4 GO:0006907 pinocytosis(GO:0006907)
0.1 17.9 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 3.2 GO:0070206 protein trimerization(GO:0070206)
0.1 0.7 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.3 GO:0070269 pyroptosis(GO:0070269)
0.0 2.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) protein O-linked fucosylation(GO:0036066)
0.0 1.0 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.0 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.2 GO:0035726 myeloid progenitor cell differentiation(GO:0002318) common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.8 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 5.0 GO:0021953 central nervous system neuron differentiation(GO:0021953)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 8.2 GO:0010038 response to metal ion(GO:0010038)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0018027 peptidyl-lysine dimethylation(GO:0018027) histone H3-K27 methylation(GO:0070734)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 2.2 GO:0031424 keratinization(GO:0031424)
0.0 1.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.7 GO:0006342 chromatin silencing(GO:0006342)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 14.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.0 3.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.7 9.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.7 2.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.3 4.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 2.3 GO:0000322 storage vacuole(GO:0000322)
0.3 6.9 GO:0001891 phagocytic cup(GO:0001891)
0.3 1.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.3 10.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 6.5 GO:0097386 glial cell projection(GO:0097386)
0.2 1.5 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 1.5 GO:0032389 MutLalpha complex(GO:0032389)
0.1 1.0 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.0 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.9 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 3.8 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 3.6 GO:0032420 stereocilium(GO:0032420)
0.1 3.3 GO:0045095 keratin filament(GO:0045095)
0.1 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.0 3.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 8.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.7 GO:0097342 ripoptosome(GO:0097342)
0.0 1.3 GO:0043034 costamere(GO:0043034)
0.0 5.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 4.5 GO:0044306 neuron projection terminus(GO:0044306)
0.0 2.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.9 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 4.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 1.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 2.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 22.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.0 13.2 GO:0008199 iron ion transmembrane transporter activity(GO:0005381) ferric iron binding(GO:0008199)
0.8 3.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.7 3.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.6 3.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.6 6.2 GO:0004064 arylesterase activity(GO:0004064)
0.5 3.8 GO:0030492 hemoglobin binding(GO:0030492)
0.5 4.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 1.4 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.4 2.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.4 2.9 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.4 3.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.3 1.6 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.3 9.5 GO:0005521 lamin binding(GO:0005521)
0.3 1.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 3.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 4.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.2 0.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 15.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 7.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 3.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 11.7 GO:0005507 copper ion binding(GO:0005507)
0.1 21.1 GO:0005496 steroid binding(GO:0005496)
0.1 2.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.4 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.5 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 4.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 10.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 3.0 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.7 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.3 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.4 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.5 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 1.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 3.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 1.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 13.2 GO:0051015 actin filament binding(GO:0051015)
0.1 1.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 1.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 2.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.4 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 3.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 1.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 7.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 10.1 PID ATR PATHWAY ATR signaling pathway
0.1 2.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 3.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 3.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 6.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.0 PID FGF PATHWAY FGF signaling pathway
0.0 1.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.4 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 ST ADRENERGIC Adrenergic Pathway
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 3.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.4 6.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 6.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 2.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 3.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 9.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 3.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 3.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 3.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 3.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 7.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 4.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 3.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 10.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 2.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.9 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription