Project
GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for SOX7
Z-value: 0.57
Motif logo
Transcription factors associated with SOX7
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX7 | hg38_v1_chr8_-_10730498_10730525 | 0.62 | 1.3e-24 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 29.3 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.6 | 15.9 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.7 | 8.0 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
| 1.8 | 7.3 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 1.6 | 6.6 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.2 | 5.4 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.1 | 5.3 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.4 | 5.2 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
| 1.6 | 4.7 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 0.3 | 3.5 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 18.9 | GO:0015630 | microtubule cytoskeleton(GO:0015630) |
| 0.4 | 15.9 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 6.3 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 6.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 5.3 | GO:0043679 | axon terminus(GO:0043679) |
| 1.6 | 4.8 | GO:0033011 | perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) |
| 0.1 | 4.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 1.2 | 3.5 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.2 | 3.4 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 3.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 30.1 | GO:0003823 | antigen binding(GO:0003823) |
| 1.0 | 15.9 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.4 | 8.0 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 1.0 | 7.3 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 1.3 | 6.6 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.4 | 6.0 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.2 | 5.4 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
| 0.8 | 5.3 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 1.0 | 5.2 | GO:0004447 | iodide peroxidase activity(GO:0004447) |
| 0.0 | 4.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.6 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 2.9 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 2.6 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 15.9 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 6.6 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 6.3 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.2 | 5.2 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.2 | 4.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 2.9 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 2.2 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 2.0 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.7 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |