GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
TBX1 | hg38_v1_chr22_+_19760714_19760794 | 0.36 | 5.2e-08 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.3 | 46.0 | GO:0097242 | beta-amyloid clearance(GO:0097242) |
0.3 | 31.9 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
0.7 | 28.5 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
5.3 | 26.3 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
0.9 | 24.8 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
0.3 | 24.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.2 | 21.8 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
1.4 | 18.5 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
0.7 | 18.1 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.2 | 16.8 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 113.1 | GO:0005615 | extracellular space(GO:0005615) |
0.3 | 61.6 | GO:0072562 | blood microparticle(GO:0072562) |
8.3 | 41.6 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
0.0 | 38.7 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.8 | 28.6 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.2 | 26.9 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
0.7 | 25.1 | GO:0042629 | mast cell granule(GO:0042629) |
4.1 | 24.4 | GO:0005879 | axonemal microtubule(GO:0005879) |
1.4 | 22.9 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
0.1 | 21.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 110.2 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
0.3 | 91.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.2 | 58.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
4.2 | 41.6 | GO:0001851 | complement component C3b binding(GO:0001851) |
6.6 | 26.3 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
1.9 | 26.1 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.4 | 23.8 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
1.1 | 21.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.4 | 21.0 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.4 | 20.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 57.1 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
0.6 | 36.3 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
0.9 | 30.5 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
0.2 | 27.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.3 | 24.7 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
0.3 | 23.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.3 | 19.2 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
0.2 | 17.1 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
0.4 | 16.9 | PID RAS PATHWAY | Regulation of Ras family activation |
0.4 | 15.1 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 82.4 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.2 | 74.3 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
0.4 | 42.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.7 | 30.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
0.2 | 29.7 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.2 | 28.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.4 | 27.3 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.3 | 24.5 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.2 | 19.4 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.3 | 19.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |