Project

GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for TBX5

Z-value: 1.06

Motif logo

Transcription factors associated with TBX5

Gene Symbol Gene ID Gene Info
ENSG00000089225.20 TBX5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX5hg38_v1_chr12_-_114406133_1144061500.469.1e-13Click!

Activity profile of TBX5 motif

Sorted Z-values of TBX5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr14_+_75280078 21.00 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr3_+_167735704 20.74 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr2_+_68734861 19.26 ENST00000467265.5
Rho GTPase activating protein 25
chr16_+_2537997 16.00 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr2_-_175005357 14.64 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr11_+_73647549 14.34 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr2_-_2326378 14.31 ENST00000647618.1
myelin transcription factor 1 like
chr12_-_44876294 13.07 ENST00000429094.7
ENST00000551601.5
ENST00000549027.5
ENST00000452445.6
neural EGFL like 2
chr2_+_68734773 12.55 ENST00000409202.8
Rho GTPase activating protein 25
chr4_-_175812746 12.36 ENST00000393658.6
glycoprotein M6A
chr14_+_75278820 11.66 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr3_-_18424533 11.51 ENST00000417717.6
SATB homeobox 1
chr19_-_38899529 10.98 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chrX_-_107775740 10.82 ENST00000372383.9
TSC22 domain family member 3
chr13_-_35855627 10.62 ENST00000379893.5
doublecortin like kinase 1
chr19_-_8514146 10.41 ENST00000255616.8
ENST00000393927.9
zinc finger protein 414
chr1_+_2050387 10.39 ENST00000378567.8
protein kinase C zeta
chr5_+_55024250 10.25 ENST00000231009.3
granzyme K
chr18_-_55302613 10.20 ENST00000561831.7
transcription factor 4
chr1_-_11805977 9.98 ENST00000376486.3
methylenetetrahydrofolate reductase
chr1_+_11806096 9.59 ENST00000312413.10
ENST00000346436.11
chloride voltage-gated channel 6
chrX_-_107717054 9.57 ENST00000503515.1
ENST00000372397.6
TSC22 domain family member 3
chr1_-_241357225 9.29 ENST00000366565.5
regulator of G protein signaling 7
chr1_-_34859717 9.02 ENST00000423898.1
ENST00000521580.3
ENST00000456842.1
small integral membrane protein 12
chrX_-_107775951 8.97 ENST00000315660.8
ENST00000372384.6
ENST00000502650.1
ENST00000506724.1
TSC22 domain family member 3
chr22_-_50578003 8.83 ENST00000405237.7
carnitine palmitoyltransferase 1B
chrX_-_49200174 8.82 ENST00000472598.5
ENST00000263233.9
ENST00000479808.5
synaptophysin
chr19_-_49441508 8.67 ENST00000221485.8
solute carrier family 17 member 7
chrX_+_21374608 8.58 ENST00000644295.1
ENST00000645074.1
ENST00000645791.1
ENST00000643220.1
connector enhancer of kinase suppressor of Ras 2
chr8_-_109644766 8.57 ENST00000533065.5
ENST00000276646.14
syntabulin
chr11_-_72674394 8.45 ENST00000418754.6
ENST00000334456.10
ENST00000542969.2
phosphodiesterase 2A
chr7_-_137343688 8.23 ENST00000348225.7
pleiotrophin
chr1_-_241357171 8.22 ENST00000440928.6
regulator of G protein signaling 7
chr1_-_241357085 8.09 ENST00000366564.5
regulator of G protein signaling 7
chr17_+_28728781 7.98 ENST00000268766.11
NIMA related kinase 8
chr22_-_50578417 7.97 ENST00000312108.12
ENST00000395650.6
carnitine palmitoyltransferase 1B
chr1_-_11805924 7.96 ENST00000418034.1
methylenetetrahydrofolate reductase
chr2_+_188291911 7.91 ENST00000410051.5
GULP PTB domain containing engulfment adaptor 1
chr1_-_11805949 7.81 ENST00000376590.9
methylenetetrahydrofolate reductase
chr7_+_97732046 7.81 ENST00000350485.8
ENST00000346867.4
ENST00000319273.10
tachykinin precursor 1
chr19_+_49877425 7.80 ENST00000622860.4
TBC1 domain family member 17
chr8_-_24956604 7.78 ENST00000610854.2
neurofilament light
chr1_+_101237009 7.71 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr7_+_143620967 7.60 ENST00000684770.1
TRPM8 channel associated factor 2
chr11_+_131911396 7.59 ENST00000425719.6
ENST00000374784.5
neurotrimin
chr2_-_201071579 7.53 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
family with sequence similarity 126 member B
chrX_+_102125703 7.52 ENST00000329035.2
transcription elongation factor A like 2
chrX_+_102125668 7.45 ENST00000372780.6
transcription elongation factor A like 2
chr10_-_97771954 7.42 ENST00000266066.4
secreted frizzled related protein 5
chr1_+_117606040 7.36 ENST00000369448.4
terminal nucleotidyltransferase 5C
chr13_-_35855758 7.33 ENST00000615680.4
doublecortin like kinase 1
chr11_-_132943671 7.29 ENST00000331898.11
opioid binding protein/cell adhesion molecule like
chr19_+_49877660 7.12 ENST00000535102.6
TBC1 domain family member 17
chrX_+_21374434 7.06 ENST00000279451.9
ENST00000645245.1
connector enhancer of kinase suppressor of Ras 2
chr1_-_202808432 7.04 ENST00000649200.1
ENST00000650493.1
lysine demethylase 5B
chr11_-_123654581 7.03 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chrX_+_21374288 7.02 ENST00000642359.1
connector enhancer of kinase suppressor of Ras 2
chr8_-_18808837 6.91 ENST00000286485.12
pleckstrin and Sec7 domain containing 3
chrX_-_107716401 6.78 ENST00000486554.1
ENST00000372390.8
TSC22 domain family member 3
chr10_+_13100075 6.62 ENST00000378747.8
ENST00000378757.6
ENST00000378752.7
ENST00000378748.7
optineurin
chr3_+_4680617 6.61 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr4_-_101347327 6.59 ENST00000394853.8
protein phosphatase 3 catalytic subunit alpha
chr10_+_114239245 6.58 ENST00000392982.8
von Willebrand factor A domain containing 2
chrX_+_21374357 6.51 ENST00000643841.1
ENST00000379510.5
ENST00000425654.7
ENST00000644798.1
ENST00000543067.6
connector enhancer of kinase suppressor of Ras 2
chr7_-_137343752 6.43 ENST00000393083.2
pleiotrophin
chr19_+_16197900 6.36 ENST00000429941.6
ENST00000291439.8
ENST00000444449.6
ENST00000589822.5
adaptor related protein complex 1 subunit mu 1
chr11_-_59615673 6.35 ENST00000263847.6
oxysterol binding protein
chr12_+_8082260 6.30 ENST00000638237.1
ENST00000339754.11
ENST00000639811.1
ENST00000639167.1
ENST00000541948.2
NECAP endocytosis associated 1
chr5_+_161850597 6.21 ENST00000634335.1
ENST00000635880.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr1_+_204828643 6.21 ENST00000339876.11
ENST00000680427.1
ENST00000403080.5
ENST00000513543.6
ENST00000430393.7
neurofascin
chr17_+_55266216 6.21 ENST00000573945.5
HLF transcription factor, PAR bZIP family member
chr12_+_57460127 6.16 ENST00000532291.5
ENST00000543426.5
ENST00000546141.5
GLI family zinc finger 1
chr9_-_133149334 6.10 ENST00000393160.7
ral guanine nucleotide dissociation stimulator
chr7_-_100656384 6.03 ENST00000461605.1
ENST00000160382.10
actin like 6B
chr19_-_13906062 6.02 ENST00000591586.5
ENST00000346736.6
break repair meiotic recombinase recruitment factor 1
chr11_-_33869816 5.97 ENST00000395833.7
LIM domain only 2
chr15_+_81296913 5.89 ENST00000394652.6
interleukin 16
chrY_+_12904102 5.85 ENST00000360160.8
ENST00000454054.5
DEAD-box helicase 3 Y-linked
chr9_-_76692181 5.72 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chr6_+_44270434 5.62 ENST00000451188.7
transmembrane protein 151B
chr19_-_54360949 5.62 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr15_-_70763539 5.60 ENST00000322954.11
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr2_+_170816868 5.59 ENST00000358196.8
glutamate decarboxylase 1
chr1_-_85259633 5.53 ENST00000344356.5
ENST00000471115.6
chromosome 1 open reading frame 52
chr6_-_13487593 5.52 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr11_-_18634332 5.52 ENST00000336349.6
SPT2 chromatin protein domain containing 1
chr5_-_135578983 5.41 ENST00000512158.6
C-X-C motif chemokine ligand 14
chr4_-_101347492 5.38 ENST00000394854.8
protein phosphatase 3 catalytic subunit alpha
chr22_-_50577915 5.37 ENST00000360719.6
ENST00000457250.5
carnitine palmitoyltransferase 1B
chr3_-_49422429 5.36 ENST00000637682.1
ENST00000427987.6
ENST00000636199.1
ENST00000638063.1
ENST00000636865.1
ENST00000458307.6
ENST00000273588.9
ENST00000635808.1
ENST00000636522.1
ENST00000636597.1
ENST00000538581.6
ENST00000395338.7
ENST00000462048.2
aminomethyltransferase
chr7_-_130440848 5.35 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
centrosomal protein 41
chr19_+_35138993 5.33 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr3_+_35680994 5.32 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr1_-_151146643 5.21 ENST00000613223.1
semaphorin 6C
chr10_-_125823089 5.18 ENST00000368774.1
ENST00000368778.7
ENST00000649536.1
uroporphyrinogen III synthase
chr2_-_223837553 5.17 ENST00000396654.7
ENST00000396653.2
ENST00000443700.5
adaptor related protein complex 1 subunit sigma 3
chr2_+_102473219 5.13 ENST00000295269.5
solute carrier family 9 member A4
chr15_-_40807450 5.12 ENST00000220496.9
ENST00000627802.1
DnaJ heat shock protein family (Hsp40) member C17
chr19_-_3500625 5.00 ENST00000672935.1
deoxyhypusine hydroxylase
chr17_+_36103819 4.99 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr1_+_168179030 4.98 ENST00000367830.3
TOR signaling pathway regulator
chr1_-_31764333 4.90 ENST00000398542.5
ENST00000373658.8
adhesion G protein-coupled receptor B2
chr22_-_19122388 4.86 ENST00000263196.12
ENST00000537045.5
ENST00000545799.5
DiGeorge syndrome critical region gene 2
chr19_-_3500664 4.86 ENST00000427575.6
deoxyhypusine hydroxylase
chr9_+_121074944 4.84 ENST00000373855.7
centriolin
chr14_+_20999255 4.80 ENST00000554422.5
ENST00000298681.5
solute carrier family 39 member 2
chr3_-_187745460 4.76 ENST00000406870.7
BCL6 transcription repressor
chr6_+_39792298 4.70 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr17_+_70169516 4.65 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr19_+_18612848 4.64 ENST00000262817.8
transmembrane protein 59 like
chr11_+_46332905 4.60 ENST00000343674.10
diacylglycerol kinase zeta
chr1_-_16352420 4.54 ENST00000375592.8
F-box protein 42
chr19_-_51372640 4.51 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr1_-_151146611 4.51 ENST00000341697.7
ENST00000368914.8
semaphorin 6C
chr6_+_44216914 4.50 ENST00000573382.3
ENST00000576476.1
myomixer, myoblast fusion factor
chr11_+_56027654 4.47 ENST00000641320.1
olfactory receptor family 5 subfamily AS member 1
chr16_+_30650932 4.46 ENST00000300835.9
proline rich 14
chr1_-_72282457 4.36 ENST00000357731.10
neuronal growth regulator 1
chr17_-_7208325 4.31 ENST00000650120.1
ENST00000648760.1
discs large MAGUK scaffold protein 4
chr7_+_30911845 4.29 ENST00000652696.1
ENST00000311813.11
aquaporin 1 (Colton blood group)
chr4_-_101347471 4.28 ENST00000323055.10
ENST00000512215.5
protein phosphatase 3 catalytic subunit alpha
chr4_+_8580387 4.28 ENST00000382487.5
G protein-coupled receptor 78
chr12_-_120904337 4.24 ENST00000353487.7
signal peptide peptidase like 3
chr1_-_19923617 4.17 ENST00000375116.3
phospholipase A2 group IIE
chr6_-_33271835 4.12 ENST00000482399.5
ENST00000445902.3
VPS52 subunit of GARP complex
chr10_-_75109085 4.11 ENST00000607131.5
dual specificity phosphatase 13
chr1_+_203026481 4.05 ENST00000367240.6
PTPRF interacting protein alpha 4
chr1_+_7784411 4.04 ENST00000613533.4
ENST00000614998.4
period circadian regulator 3
chr19_-_10309783 4.03 ENST00000403352.1
ENST00000403903.7
zinc finger GATA like protein 1
chr6_+_292050 3.99 ENST00000344450.9
dual specificity phosphatase 22
chr1_+_13583762 3.97 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chr15_+_81196871 3.97 ENST00000559383.5
ENST00000394660.6
ENST00000683961.1
interleukin 16
chr8_-_52409743 3.92 ENST00000276480.11
ST18 C2H2C-type zinc finger transcription factor
chr1_+_59814939 3.90 ENST00000371208.5
hook microtubule tethering protein 1
chr20_-_40689228 3.89 ENST00000373313.3
MAF bZIP transcription factor B
chr20_+_2536573 3.88 ENST00000358864.2
transmembrane channel like 2
chr8_-_22131043 3.86 ENST00000312841.9
HR lysine demethylase and nuclear receptor corepressor
chr11_+_65712231 3.86 ENST00000530446.5
ENST00000534104.5
ENST00000341318.9
ENST00000530605.5
ENST00000528198.5
ENST00000531880.1
ENST00000534650.5
lysine acetyltransferase 5
chr20_+_59300547 3.86 ENST00000644821.1
endothelin 3
chr10_-_125823221 3.86 ENST00000420761.5
ENST00000368797.10
uroporphyrinogen III synthase
chr17_+_27471999 3.86 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
kinase suppressor of ras 1
chr7_-_150978284 3.73 ENST00000262186.10
potassium voltage-gated channel subfamily H member 2
chr1_+_148889403 3.70 ENST00000464103.5
ENST00000534536.5
ENST00000369356.8
ENST00000369354.7
ENST00000369347.8
ENST00000369349.7
ENST00000369351.7
phosphodiesterase 4D interacting protein
chr16_+_30651039 3.69 ENST00000542965.2
proline rich 14
chr17_+_32487686 3.68 ENST00000584792.5
cyclin dependent kinase 5 regulatory subunit 1
chr19_-_46023046 3.68 ENST00000008938.5
peptidoglycan recognition protein 1
chr12_+_57459782 3.66 ENST00000228682.7
GLI family zinc finger 1
chr3_+_50267606 3.65 ENST00000618865.4
semaphorin 3B
chr3_-_101513175 3.64 ENST00000394091.5
ENST00000394094.6
ENST00000394095.7
ENST00000348610.3
ENST00000314261.11
SUMO specific peptidase 7
chr13_-_113453524 3.63 ENST00000612156.2
ENST00000375418.7
ADP-ribosylhydrolase like 1
chr3_-_49689053 3.63 ENST00000449682.2
macrophage stimulating 1
chr11_+_65711991 3.59 ENST00000377046.7
ENST00000352980.8
lysine acetyltransferase 5
chr8_-_22131003 3.56 ENST00000381418.9
HR lysine demethylase and nuclear receptor corepressor
chrX_+_70423031 3.55 ENST00000453994.6
ENST00000538649.5
ENST00000536730.5
glycerophosphodiester phosphodiesterase domain containing 2
chr17_+_49495286 3.55 ENST00000172229.8
nerve growth factor receptor
chr14_+_91114364 3.55 ENST00000518868.5
D-glutamate cyclase
chr16_+_30957960 3.52 ENST00000684162.1
SET domain containing 1A, histone lysine methyltransferase
chr6_+_127266832 3.50 ENST00000356799.6
ENST00000368314.6
ring finger protein 146
chr10_+_133379238 3.50 ENST00000357296.7
ENST00000278060.10
polyamine oxidase
chr7_+_5879827 3.48 ENST00000416608.5
oncomodulin
chr6_+_83067655 3.47 ENST00000237163.9
ENST00000349129.7
DOP1 leucine zipper like protein A
chr5_+_140107777 3.45 ENST00000505703.2
ENST00000651386.1
purine rich element binding protein A
chr2_+_108449178 3.44 ENST00000309863.11
ENST00000409821.5
GRIP and coiled-coil domain containing 2
chr1_-_150010675 3.42 ENST00000417191.2
ENST00000581312.6
OTU deubiquitinase 7B
chr19_+_48364361 3.41 ENST00000344846.7
synaptogyrin 4
chr11_-_45917867 3.38 ENST00000378750.10
peroxisomal biogenesis factor 16
chr11_-_798261 3.37 ENST00000530360.2
ENST00000531437.5
ENST00000628067.3
solute carrier family 25 member 22
chr19_-_42427379 3.36 ENST00000244289.9
lipase E, hormone sensitive type
chr6_+_39793008 3.34 ENST00000398904.6
dishevelled associated activator of morphogenesis 2
chr20_+_59300402 3.31 ENST00000311585.11
ENST00000371028.6
endothelin 3
chr21_+_42219123 3.28 ENST00000398449.8
ATP binding cassette subfamily G member 1
chr17_+_17042433 3.25 ENST00000651222.2
myosin phosphatase Rho interacting protein
chrX_+_70423301 3.24 ENST00000374382.4
glycerophosphodiester phosphodiesterase domain containing 2
chr3_+_63819341 3.24 ENST00000647022.1
chromosome 3 open reading frame 49
chr6_-_41201128 3.23 ENST00000483722.2
triggering receptor expressed on myeloid cells like 2
chr1_-_169893876 3.13 ENST00000367771.11
ENST00000367772.8
SCY1 like pseudokinase 3
chr20_+_34363241 3.10 ENST00000486883.5
ENST00000374864.10
ENST00000535650.7
ENST00000670516.1
ENST00000665484.1
ENST00000654846.1
ENST00000665428.1
ENST00000660337.1
ENST00000262650.10
ENST00000665346.1
itchy E3 ubiquitin protein ligase
chrX_-_131289412 3.07 ENST00000652189.1
ENST00000651556.1
immunoglobulin superfamily member 1
chr10_-_124093582 3.07 ENST00000462406.1
ENST00000435907.6
carbohydrate sulfotransferase 15
chr9_+_122375286 3.06 ENST00000373698.7
prostaglandin-endoperoxide synthase 1
chr6_+_39792993 3.06 ENST00000538976.5
dishevelled associated activator of morphogenesis 2
chr7_+_97005538 3.03 ENST00000518156.3
distal-less homeobox 6
chr6_-_132757883 3.00 ENST00000525289.5
ENST00000326499.11
vanin 2
chr2_-_108989206 2.95 ENST00000258443.7
ENST00000409271.5
ENST00000376651.1
ectodysplasin A receptor
chr15_+_90265634 2.94 ENST00000379095.5
neugrin, neurite outgrowth associated
chr5_+_66828762 2.93 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr17_+_79024142 2.92 ENST00000579760.6
ENST00000339142.6
C1q and TNF related 1
chr21_+_42219111 2.92 ENST00000450121.5
ENST00000361802.6
ATP binding cassette subfamily G member 1
chr14_+_71598229 2.91 ENST00000537413.5
signal induced proliferation associated 1 like 1
chr17_-_37609361 2.89 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr17_-_27893339 2.89 ENST00000460380.6
ENST00000379102.8
ENST00000508862.5
ENST00000582441.1
LYR motif containing 9
novel protein
chr2_+_100974849 2.89 ENST00000450763.1
neuronal PAS domain protein 2
chr3_-_61251376 2.86 ENST00000476844.5
ENST00000488467.5
ENST00000492590.6
ENST00000468189.5
fragile histidine triad diadenosine triphosphatase
chrX_-_131289266 2.85 ENST00000370910.5
ENST00000370901.4
ENST00000361420.8
ENST00000370903.8
immunoglobulin superfamily member 1
chr18_-_63318674 2.83 ENST00000589955.2
BCL2 apoptosis regulator
chr19_+_7669043 2.83 ENST00000221515.6
resistin
chr2_+_170816562 2.81 ENST00000625689.2
ENST00000375272.5
glutamate decarboxylase 1
chr7_-_138981307 2.80 ENST00000440172.5
ENST00000422774.2
KIAA1549
chr15_+_84884672 2.79 ENST00000286749.3
solute carrier family 28 member 1
chr1_+_54998927 2.77 ENST00000651561.1
barttin CLCNK type accessory subunit beta

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.7 GO:1904397 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
4.5 36.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
4.3 25.7 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
4.1 16.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
4.0 12.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
3.7 11.0 GO:2000777 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
3.6 32.7 GO:0001661 conditioned taste aversion(GO:0001661)
3.3 9.8 GO:0060032 notochord regression(GO:0060032)
2.9 8.7 GO:0042137 sequestering of neurotransmitter(GO:0042137)
2.6 7.8 GO:1903937 response to acrylamide(GO:1903937)
2.6 7.7 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
2.3 9.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
2.1 8.5 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
2.1 8.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
2.1 10.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
2.1 6.2 GO:0009720 detection of hormone stimulus(GO:0009720)
2.1 6.2 GO:0009447 putrescine catabolic process(GO:0009447)
1.9 7.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
1.8 5.5 GO:0010847 regulation of chromatin assembly(GO:0010847)
1.7 10.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.7 5.0 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
1.5 4.6 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.5 17.6 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.4 4.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
1.4 6.9 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
1.4 9.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
1.3 1.3 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
1.3 3.9 GO:0060005 vestibular reflex(GO:0060005)
1.3 5.1 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
1.3 3.8 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
1.3 3.8 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
1.2 3.7 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
1.2 6.2 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.2 3.7 GO:0021718 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
1.2 4.8 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.2 4.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
1.1 3.4 GO:0034499 late endosome to Golgi transport(GO:0034499)
1.1 4.5 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
1.1 6.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.1 13.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
1.1 5.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.0 2.9 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.0 3.9 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
1.0 14.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.0 7.6 GO:1903960 negative regulation of anion transmembrane transport(GO:1903960)
0.9 6.6 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.9 3.7 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.9 20.3 GO:0006853 carnitine shuttle(GO:0006853)
0.9 9.9 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.9 5.3 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.9 7.0 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.9 3.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.8 0.8 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.8 6.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.8 2.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.8 4.0 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.8 5.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.7 3.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.7 3.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.7 6.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.7 2.0 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.6 1.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.6 8.0 GO:0035330 regulation of hippo signaling(GO:0035330)
0.6 1.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.5 9.5 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.5 2.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.5 1.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.4 6.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.4 3.6 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.4 2.7 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.4 2.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.4 2.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.4 3.9 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 2.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.4 17.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.4 3.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.4 9.9 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.4 14.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.4 2.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.4 6.4 GO:0044126 growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126)
0.4 3.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4 1.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) sarcomerogenesis(GO:0048769)
0.4 8.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 1.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.4 6.8 GO:0090527 actin filament reorganization(GO:0090527)
0.4 2.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 1.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.4 10.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.4 7.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.4 1.9 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.4 1.1 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.4 5.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 15.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 2.4 GO:0070842 aggresome assembly(GO:0070842)
0.3 1.0 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.3 2.7 GO:0046137 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.3 15.0 GO:0008038 neuron recognition(GO:0008038)
0.3 3.9 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.3 2.6 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 6.4 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.3 8.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 1.2 GO:0002215 defense response to nematode(GO:0002215)
0.3 0.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 10.8 GO:0048665 neuron fate specification(GO:0048665)
0.3 7.5 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.3 2.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 4.5 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 2.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 0.8 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.3 2.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 1.4 GO:0045759 negative regulation of action potential(GO:0045759)
0.3 0.5 GO:0071288 cellular response to mercury ion(GO:0071288)
0.3 6.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.3 4.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 4.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.3 1.0 GO:0010193 response to ozone(GO:0010193)
0.2 3.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 1.5 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 2.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.2 2.9 GO:0051775 response to redox state(GO:0051775)
0.2 2.1 GO:1901626 regulation of postsynaptic membrane organization(GO:1901626)
0.2 1.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 6.2 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.1 GO:0002554 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.2 19.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.2 4.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 21.2 GO:0007422 peripheral nervous system development(GO:0007422)
0.2 1.4 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.2 4.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 14.3 GO:0007602 phototransduction(GO:0007602)
0.2 2.6 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 3.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 1.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 2.2 GO:0097070 ductus arteriosus closure(GO:0097070)
0.2 1.4 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 3.9 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.2 2.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 7.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.2 2.4 GO:0006600 creatine metabolic process(GO:0006600)
0.1 2.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 2.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.4 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 3.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1 3.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 4.0 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 2.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 10.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 1.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 1.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.5 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 2.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.6 GO:0045475 locomotor rhythm(GO:0045475)
0.1 5.1 GO:1901998 toxin transport(GO:1901998)
0.1 0.5 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 5.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 2.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 1.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 10.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 2.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 5.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 36.9 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 4.1 GO:0010107 potassium ion import(GO:0010107)
0.1 0.7 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 9.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 2.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 2.8 GO:0048536 spleen development(GO:0048536)
0.1 1.1 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.8 GO:0035082 axoneme assembly(GO:0035082)
0.1 1.0 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 4.0 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.2 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.1 0.8 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 4.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 2.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 2.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 5.1 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 6.5 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 3.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 2.4 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 4.4 GO:0007631 feeding behavior(GO:0007631)
0.1 2.0 GO:0060612 adipose tissue development(GO:0060612)
0.1 2.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 3.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 1.1 GO:0021591 ventricular system development(GO:0021591)
0.0 4.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 2.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 4.0 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 2.4 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 2.2 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.8 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.3 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 2.8 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.2 GO:0048599 oocyte development(GO:0048599)
0.0 1.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 15.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.6 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 3.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 3.0 GO:0035113 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 1.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 1.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.8 GO:0007286 spermatid development(GO:0007286)
0.0 0.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 2.3 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.1 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 2.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.6 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.0 1.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 1.1 GO:0006958 complement activation, classical pathway(GO:0006958)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 32.7 GO:0035976 AP1 complex(GO:0035976)
2.1 22.9 GO:0005955 calcineurin complex(GO:0005955)
1.9 7.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.9 7.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.3 10.4 GO:0045179 apical cortex(GO:0045179)
1.3 3.9 GO:0032426 stereocilium tip(GO:0032426)
1.2 6.2 GO:0097454 Schwann cell microvillus(GO:0097454)
1.2 11.0 GO:0072687 meiotic spindle(GO:0072687)
1.2 4.7 GO:0070695 FHF complex(GO:0070695)
1.1 17.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.1 4.3 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.8 4.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.7 3.7 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.7 3.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.7 2.2 GO:0035517 PR-DUB complex(GO:0035517)
0.6 1.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.6 3.7 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.6 4.1 GO:1990745 EARP complex(GO:1990745)
0.6 8.6 GO:0097433 dense body(GO:0097433)
0.5 1.6 GO:0070195 growth hormone receptor complex(GO:0070195)
0.5 6.9 GO:0060077 inhibitory synapse(GO:0060077) clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.5 5.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.5 12.4 GO:0044295 axonal growth cone(GO:0044295)
0.5 32.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 6.4 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.4 2.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 17.8 GO:0097546 ciliary base(GO:0097546)
0.4 1.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 7.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 8.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.3 5.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 11.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.3 0.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 3.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 2.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 6.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 34.2 GO:0043204 perikaryon(GO:0043204)
0.2 2.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 3.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 4.0 GO:0048786 presynaptic active zone(GO:0048786)
0.2 1.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.2 6.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 2.4 GO:0005883 neurofilament(GO:0005883)
0.2 6.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 29.6 GO:0055037 recycling endosome(GO:0055037)
0.2 21.5 GO:0005604 basement membrane(GO:0005604)
0.2 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 3.2 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 12.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.8 GO:0046930 pore complex(GO:0046930)
0.1 8.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 8.8 GO:0005581 collagen trimer(GO:0005581)
0.1 6.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 3.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 4.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 4.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 2.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 2.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 25.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 1.8 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 4.8 GO:0031904 endosome lumen(GO:0031904)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 3.7 GO:0016235 aggresome(GO:0016235)
0.1 1.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 1.7 GO:0043218 compact myelin(GO:0043218)
0.1 5.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 3.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 11.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 5.3 GO:0036064 ciliary basal body(GO:0036064)
0.1 3.7 GO:0035580 specific granule lumen(GO:0035580)
0.1 2.1 GO:0045095 keratin filament(GO:0045095)
0.1 2.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 11.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 5.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.8 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.9 GO:0032982 myosin filament(GO:0032982)
0.0 2.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.9 GO:0030426 growth cone(GO:0030426)
0.0 2.9 GO:0030018 Z disc(GO:0030018)
0.0 10.0 GO:0045202 synapse(GO:0045202)
0.0 2.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 7.4 GO:0030424 axon(GO:0030424)
0.0 3.9 GO:0001650 fibrillar center(GO:0001650)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 5.5 GO:0010008 endosome membrane(GO:0010008)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 5.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 22.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
4.3 25.7 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
4.0 36.1 GO:0043426 MRF binding(GO:0043426)
3.7 14.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
3.7 11.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
2.3 9.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
2.0 25.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.8 16.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
1.8 5.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
1.7 8.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
1.7 5.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
1.7 5.0 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.6 6.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
1.6 9.6 GO:0031708 endothelin B receptor binding(GO:0031708)
1.5 6.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
1.4 6.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.3 34.2 GO:0043274 phospholipase binding(GO:0043274)
1.2 3.7 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
1.1 4.5 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
1.1 3.4 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.1 3.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
1.1 6.4 GO:0008142 oxysterol binding(GO:0008142)
1.0 5.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.9 3.7 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.9 3.6 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.9 2.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.9 6.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.9 3.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.8 6.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.8 4.0 GO:0034648 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.7 3.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.7 4.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223) glycerol transmembrane transporter activity(GO:0015168)
0.7 2.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.7 8.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.7 6.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.7 2.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.7 2.6 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.7 5.9 GO:0034711 inhibin binding(GO:0034711)
0.7 5.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.7 13.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.6 3.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.6 7.7 GO:0046625 sphingolipid binding(GO:0046625)
0.6 1.9 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.6 38.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.6 1.9 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.6 3.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.6 4.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.6 5.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.5 1.6 GO:0070052 collagen V binding(GO:0070052)
0.5 2.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.5 4.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.5 3.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.5 5.1 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.5 7.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.5 5.0 GO:0015250 water channel activity(GO:0015250)
0.5 9.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.5 10.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 3.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 4.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 2.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.4 4.5 GO:0005549 odorant binding(GO:0005549)
0.4 3.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 6.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 2.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.4 17.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 7.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.4 1.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.4 1.6 GO:0005148 prolactin receptor binding(GO:0005148)
0.4 2.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.4 2.2 GO:0030172 troponin C binding(GO:0030172)
0.3 1.0 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 2.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.3 15.0 GO:0050699 WW domain binding(GO:0050699)
0.3 7.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 0.9 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 2.4 GO:0004111 creatine kinase activity(GO:0004111)
0.3 4.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 4.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 2.6 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 0.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 1.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 3.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 4.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 8.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 8.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 2.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 3.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) retinal binding(GO:0016918)
0.2 4.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 9.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 2.8 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.2 1.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 3.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 3.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 3.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 2.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 3.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 1.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 5.4 GO:0008009 chemokine activity(GO:0008009)
0.2 18.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.5 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 2.9 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 4.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.0 GO:0051373 FATZ binding(GO:0051373)
0.2 2.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 2.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 8.8 GO:0015485 cholesterol binding(GO:0015485)
0.1 52.2 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 4.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 2.4 GO:0031005 filamin binding(GO:0031005)
0.1 6.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 3.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 7.5 GO:0050681 androgen receptor binding(GO:0050681)
0.1 2.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 2.1 GO:0043495 protein anchor(GO:0043495)
0.1 2.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 6.1 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.4 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 11.3 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.0 GO:0031014 troponin T binding(GO:0031014)
0.1 5.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 1.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 14.0 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 2.8 GO:0016248 channel inhibitor activity(GO:0016248)
0.1 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 14.3 GO:0044325 ion channel binding(GO:0044325)
0.1 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 21.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.2 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 1.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 3.8 GO:0020037 heme binding(GO:0020037)
0.1 1.0 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 4.9 GO:0004497 monooxygenase activity(GO:0004497)
0.1 4.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 2.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 3.3 GO:0002039 p53 binding(GO:0002039)
0.0 1.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.0 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 3.2 GO:0005179 hormone activity(GO:0005179)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 7.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 5.8 GO:0008017 microtubule binding(GO:0008017)
0.0 6.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 3.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.4 GO:0005516 calmodulin binding(GO:0005516)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 32.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.6 16.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.5 14.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.4 29.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.3 3.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3 22.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 10.4 PID RAS PATHWAY Regulation of Ras family activation
0.3 11.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3 3.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.3 10.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 7.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.2 16.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 1.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.2 6.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 9.8 PID ARF6 PATHWAY Arf6 signaling events
0.2 6.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 9.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 1.9 PID IL27 PATHWAY IL27-mediated signaling events
0.2 1.7 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.2 9.6 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 3.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 10.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 5.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 12.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 4.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 5.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 3.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 4.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.9 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 5.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 32.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.7 23.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.6 8.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.5 10.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 16.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.4 3.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.3 14.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 4.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 7.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.3 6.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 6.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 4.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 23.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.3 8.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 6.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.3 5.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 4.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 6.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 49.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 4.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 8.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 15.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 8.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 2.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 15.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 1.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 6.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 4.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 8.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 2.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 39.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 1.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 2.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.2 3.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 2.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 6.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 5.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 9.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 6.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 5.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 5.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 5.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 2.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 5.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 3.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling