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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TEAD4

Z-value: 1.14

Motif logo

Transcription factors associated with TEAD4

Gene Symbol Gene ID Gene Info
ENSG00000197905.10 TEAD4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEAD4hg38_v1_chr12_+_2959870_2959953,
hg38_v1_chr12_+_2959296_2959431
-0.606.0e-23Click!

Activity profile of TEAD4 motif

Sorted Z-values of TEAD4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_91146195 35.61 ENST00000548218.1
decorin
chr17_-_31297231 20.58 ENST00000247271.5
oligodendrocyte myelin glycoprotein
chr12_-_91178520 18.63 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
decorin
chr19_+_9087061 17.75 ENST00000641627.1
olfactory receptor family 1 subfamily M member 1
chr21_+_46458846 16.75 ENST00000417564.3
ENST00000651436.1
ENST00000400274.5
ENST00000457905.7
ENST00000466639.5
ENST00000435722.7
disco interacting protein 2 homolog A
chr5_-_42811884 16.30 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr3_+_101827982 15.99 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr19_+_9185594 15.86 ENST00000344248.4
olfactory receptor family 7 subfamily D member 2
chr2_+_200440649 15.75 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr13_-_67230377 15.49 ENST00000544246.5
ENST00000377861.4
protocadherin 9
chr3_-_18424533 14.92 ENST00000417717.6
SATB homeobox 1
chr13_-_67230313 14.89 ENST00000377865.7
protocadherin 9
chr17_+_40062810 14.36 ENST00000584985.5
ENST00000264637.8
thyroid hormone receptor alpha
chr8_-_27258414 13.56 ENST00000523048.5
stathmin 4
chr17_-_68955332 13.11 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr14_-_106165730 12.32 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr7_-_36985060 12.25 ENST00000396040.6
engulfment and cell motility 1
chr1_-_158686700 12.05 ENST00000643759.2
spectrin alpha, erythrocytic 1
chr8_-_27258386 11.96 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
stathmin 4
chr6_-_52840843 11.90 ENST00000370989.6
glutathione S-transferase alpha 5
chr3_+_138348823 11.66 ENST00000475711.5
ENST00000464896.5
muscle RAS oncogene homolog
chr2_-_136118142 11.60 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr1_-_11848345 11.11 ENST00000376476.1
natriuretic peptide A
chr4_+_153222402 10.76 ENST00000676335.1
ENST00000675146.1
tripartite motif containing 2
chr6_-_46325641 10.60 ENST00000330430.10
ENST00000405162.2
regulator of calcineurin 2
chrX_+_21374608 10.49 ENST00000644295.1
ENST00000645074.1
ENST00000645791.1
ENST00000643220.1
connector enhancer of kinase suppressor of Ras 2
chr6_-_109009498 10.47 ENST00000356644.7
sestrin 1
chr17_+_49788672 10.47 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
lysine acetyltransferase 7
chr6_-_152168349 10.27 ENST00000539504.5
spectrin repeat containing nuclear envelope protein 1
chr2_-_196068812 10.12 ENST00000410072.5
ENST00000312428.11
dynein axonemal heavy chain 7
chr5_+_174045673 9.76 ENST00000303177.8
ENST00000519867.5
neuronal vesicle trafficking associated 2
chr2_-_89160329 9.54 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr14_-_106269133 9.29 ENST00000390609.3
immunoglobulin heavy variable 3-23
chr16_+_30374794 9.17 ENST00000322861.12
myosin light chain, phosphorylatable, fast skeletal muscle
chrX_+_21374434 8.96 ENST00000279451.9
ENST00000645245.1
connector enhancer of kinase suppressor of Ras 2
chrX_+_21374288 8.96 ENST00000642359.1
connector enhancer of kinase suppressor of Ras 2
chr6_-_152168291 8.85 ENST00000354674.5
spectrin repeat containing nuclear envelope protein 1
chr4_-_39032343 8.76 ENST00000381938.4
transmembrane protein 156
chr14_-_106593319 8.69 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr2_-_127220293 8.57 ENST00000664447.2
ENST00000409327.2
cytochrome P450 family 27 subfamily C member 1
chr2_-_178807415 8.36 ENST00000342992.10
ENST00000460472.6
ENST00000589042.5
ENST00000591111.5
ENST00000360870.10
titin
chrX_+_21374357 8.32 ENST00000643841.1
ENST00000379510.5
ENST00000425654.7
ENST00000644798.1
ENST00000543067.6
connector enhancer of kinase suppressor of Ras 2
chr3_+_124094663 8.29 ENST00000460856.5
ENST00000240874.7
kalirin RhoGEF kinase
chr7_+_77696423 8.08 ENST00000334955.13
round spermatid basic protein 1 like
chr13_-_44437214 8.01 ENST00000622051.1
TSC22 domain family member 1
chr22_-_50085331 7.89 ENST00000395876.6
modulator of VRAC current 1
chr19_+_35138993 7.82 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr7_+_148133684 7.72 ENST00000628930.2
contactin associated protein 2
chr2_+_90021567 7.66 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr1_+_160796157 7.62 ENST00000263285.11
ENST00000368039.2
lymphocyte antigen 9
chr19_+_35139724 7.37 ENST00000588715.5
ENST00000588607.5
FXYD domain containing ion transport regulator 1
chr10_-_49762276 7.27 ENST00000374103.9
oxoglutarate dehydrogenase L
chr10_-_49762335 7.15 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr15_+_33968484 7.13 ENST00000383263.7
cholinergic receptor muscarinic 5
chr4_-_148444674 7.10 ENST00000344721.8
nuclear receptor subfamily 3 group C member 2
chr1_+_241532370 7.09 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr4_+_70430487 7.03 ENST00000413702.5
mucin 7, secreted
chr9_-_101487120 7.03 ENST00000374848.8
post-GPI attachment to proteins GalNAc transferase 4
chr4_+_153222307 6.91 ENST00000675899.1
ENST00000675611.1
ENST00000674872.1
ENST00000676167.1
tripartite motif containing 2
chr2_-_127811149 6.89 ENST00000322313.9
ENST00000393006.5
ENST00000409658.7
ENST00000436787.5
WD repeat domain 33
chr22_-_50085414 6.83 ENST00000311597.10
modulator of VRAC current 1
chr1_-_154956086 6.62 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBX homeobox interacting protein 1
chr9_-_15472732 6.52 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr8_+_24294044 6.47 ENST00000265769.9
ADAM metallopeptidase domain 28
chr15_+_80441229 6.38 ENST00000533983.5
ENST00000527771.5
ENST00000525103.1
aryl hydrocarbon receptor nuclear translocator 2
chr12_+_109116581 6.38 ENST00000338432.11
acetyl-CoA carboxylase beta
chr14_-_106658251 6.33 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr12_+_12725897 6.28 ENST00000326765.10
apolipoprotein L domain containing 1
chr10_-_60389833 6.21 ENST00000280772.7
ankyrin 3
chr11_-_59866478 6.20 ENST00000257264.4
transcobalamin 1
chr10_-_88952763 6.10 ENST00000224784.10
actin alpha 2, smooth muscle
chr3_+_138348592 6.10 ENST00000621127.4
ENST00000494949.5
muscle RAS oncogene homolog
chr1_+_45551031 6.08 ENST00000481885.5
ENST00000471651.1
aldo-keto reductase family 1 member A1
chr2_-_60553558 6.06 ENST00000642439.1
ENST00000356842.9
BAF chromatin remodeling complex subunit BCL11A
chr3_+_138348570 6.06 ENST00000423968.7
muscle RAS oncogene homolog
chr10_-_73651013 5.94 ENST00000372873.8
synaptopodin 2 like
chr17_+_4951758 5.87 ENST00000518175.1
enolase 3
chr5_-_10307821 5.73 ENST00000296658.4
carboxymethylenebutenolidase homolog
chr16_+_33009175 5.69 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr2_-_60553618 5.60 ENST00000643716.1
ENST00000359629.10
ENST00000642384.2
ENST00000335712.11
BAF chromatin remodeling complex subunit BCL11A
chr5_+_140882116 5.57 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chrX_+_37780049 5.47 ENST00000378588.5
cytochrome b-245 beta chain
chr20_-_23826721 5.46 ENST00000304725.3
cystatin SA
chr11_-_117876612 5.45 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr11_+_46936710 5.43 ENST00000378618.6
ENST00000278460.12
ENST00000395460.6
ENST00000378615.7
chromosome 11 open reading frame 49
chr1_-_156282799 5.40 ENST00000361813.5
SMG5 nonsense mediated mRNA decay factor
chr5_+_180988840 5.39 ENST00000342868.7
butyrophilin like 3
chr17_+_42458844 5.34 ENST00000393829.6
ENST00000537728.5
ENST00000343619.9
ENST00000264649.10
ENST00000585525.5
ENST00000544137.5
ENST00000589727.5
ENST00000587824.5
ATPase H+ transporting V0 subunit a1
chr4_-_185810894 5.24 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chr11_-_10568571 5.22 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr7_+_87934242 5.19 ENST00000413139.2
ENST00000412441.5
ENST00000683525.1
ENST00000398201.8
ENST00000265727.11
ENST00000398209.7
ENST00000684002.1
ADAM metallopeptidase domain 22
chr12_+_68808143 5.18 ENST00000258149.11
ENST00000428863.6
ENST00000393412.7
MDM2 proto-oncogene
chr8_+_54457927 5.18 ENST00000297316.5
SRY-box transcription factor 17
chr11_-_10568650 5.18 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr2_+_1414382 5.17 ENST00000423320.5
ENST00000346956.7
ENST00000382198.5
thyroid peroxidase
chr1_+_241532121 5.15 ENST00000366558.7
kynurenine 3-monooxygenase
chr4_-_185395882 5.13 ENST00000505916.6
LRP2 binding protein
chr3_+_189631373 5.07 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr12_-_110920710 5.04 ENST00000546404.1
myosin light chain 2
chr4_-_88823165 5.02 ENST00000508369.5
family with sequence similarity 13 member A
chr19_-_3786363 5.00 ENST00000310132.11
megakaryocyte-associated tyrosine kinase
chr3_+_124094696 4.93 ENST00000360013.7
ENST00000684186.1
ENST00000684276.1
kalirin RhoGEF kinase
chr4_-_47981535 4.91 ENST00000402813.9
cyclic nucleotide gated channel subunit alpha 1
chr12_+_10307818 4.90 ENST00000350274.9
ENST00000336164.9
killer cell lectin like receptor D1
chr8_-_69833338 4.89 ENST00000524945.5
solute carrier organic anion transporter family member 5A1
chr15_+_81182579 4.87 ENST00000302987.9
interleukin 16
chr19_+_57120043 4.82 ENST00000254181.8
ENST00000600940.1
ubiquitin specific peptidase 29
chr5_-_139439488 4.82 ENST00000302060.10
DnaJ heat shock protein family (Hsp40) member C18
chr2_-_86337617 4.72 ENST00000538924.7
ENST00000535845.6
receptor accessory protein 1
chr14_-_106062670 4.62 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr2_-_86337654 4.62 ENST00000165698.9
receptor accessory protein 1
chrX_-_54998530 4.62 ENST00000545676.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr8_+_49911396 4.58 ENST00000642720.2
syntrophin gamma 1
chr20_+_1266263 4.47 ENST00000649598.1
ENST00000381867.6
ENST00000381873.7
syntaphilin
chr2_-_160200310 4.43 ENST00000620391.4
integrin subunit beta 6
chr12_-_48999363 4.33 ENST00000421952.3
dendrin
chr14_-_106360320 4.31 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr12_+_18262730 4.29 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr1_+_65992389 4.23 ENST00000423207.6
phosphodiesterase 4B
chr2_-_210303608 4.15 ENST00000341685.8
myosin light chain 1
chr2_-_160200289 4.13 ENST00000409872.1
integrin subunit beta 6
chr2_+_38666059 4.09 ENST00000272252.10
ENST00000410063.5
galactose mutarotase
chr4_+_54229261 4.04 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr4_-_144140683 4.04 ENST00000324022.14
glycophorin A (MNS blood group)
chr11_+_62242232 3.98 ENST00000244926.4
secretoglobin family 1D member 2
chr6_+_25754699 3.98 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr6_-_27867581 3.96 ENST00000331442.5
H1.5 linker histone, cluster member
chr6_+_31670167 3.96 ENST00000375864.4
lymphocyte antigen 6 family member G5B
chr19_+_10430786 3.92 ENST00000293683.9
phosphodiesterase 4A
chr14_-_106335613 3.91 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr17_-_18682262 3.91 ENST00000454745.2
ENST00000395675.7
forkhead box O3B
chr1_+_163068775 3.86 ENST00000421743.6
regulator of G protein signaling 4
chr4_+_95091462 3.85 ENST00000264568.8
bone morphogenetic protein receptor type 1B
chr16_+_30375820 3.75 ENST00000566955.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_-_160200251 3.66 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
integrin subunit beta 6
chr5_-_32312913 3.65 ENST00000280285.9
ENST00000382142.8
ENST00000264934.5
myotubularin related protein 12
chr14_-_106088573 3.55 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr14_-_105987068 3.47 ENST00000390594.3
immunoglobulin heavy variable 1-2
chr15_-_19988117 3.46 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr6_-_32666648 3.29 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
major histocompatibility complex, class II, DQ beta 1
chr19_-_40750302 3.27 ENST00000598485.6
ENST00000378313.7
ENST00000470681.5
chromosome 19 open reading frame 54
chr10_-_1200360 3.23 ENST00000381310.7
ENST00000381305.1
adenosine deaminase RNA specific B2 (inactive)
chrX_-_32412220 3.19 ENST00000619831.5
dystrophin
chr1_+_171314171 3.14 ENST00000367749.4
flavin containing dimethylaniline monoxygenase 4
chr12_+_6444932 3.10 ENST00000266557.4
CD27 molecule
chr19_-_3786408 3.09 ENST00000395040.6
megakaryocyte-associated tyrosine kinase
chr4_-_144140635 3.09 ENST00000512064.5
ENST00000512789.5
ENST00000504786.5
ENST00000503627.2
ENST00000642713.1
ENST00000643148.1
ENST00000642738.1
ENST00000642295.1
ENST00000646447.1
ENST00000535709.6
glycophorin A (MNS blood group)
chr13_-_46105009 3.08 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
carboxypeptidase B2
chr6_-_166168700 3.01 ENST00000366871.7
T-box transcription factor T
chr9_+_68356899 3.00 ENST00000396392.5
phosphoglucomutase 5
chr9_-_127847117 2.95 ENST00000480266.5
endoglin
chr8_+_24294107 2.93 ENST00000437154.6
ADAM metallopeptidase domain 28
chr12_+_32107151 2.87 ENST00000548411.5
BICD cargo adaptor 1
chr6_-_166168612 2.84 ENST00000296946.6
T-box transcription factor T
chr2_-_73642413 2.83 ENST00000272425.4
N-acetyltransferase 8 (putative)
chr7_+_80638633 2.82 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chrX_-_33128360 2.75 ENST00000378677.6
dystrophin
chr11_-_84273188 2.69 ENST00000330014.11
ENST00000418306.6
ENST00000531015.5
discs large MAGUK scaffold protein 2
chr2_-_187554473 2.67 ENST00000453013.5
ENST00000417013.5
tissue factor pathway inhibitor
chr17_+_46511511 2.64 ENST00000576629.5
leucine rich repeat containing 37 member A2
chr2_+_33476640 2.55 ENST00000425210.5
ENST00000444784.5
ENST00000423159.5
ENST00000403687.8
RAS guanyl releasing protein 3
chr6_+_27957241 2.52 ENST00000244623.1
olfactory receptor family 2 subfamily B member 6
chr19_-_3786254 2.35 ENST00000585778.5
megakaryocyte-associated tyrosine kinase
chr11_-_66546021 2.33 ENST00000310442.5
zinc finger DHHC-type containing 24
chr7_+_152759744 2.25 ENST00000377776.7
ENST00000256001.13
ENST00000397282.2
actin related protein 3B
chr4_+_118034480 2.24 ENST00000296499.6
N-deacetylase and N-sulfotransferase 3
chr8_+_49911604 2.22 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr13_+_23979794 2.21 ENST00000424834.6
ENST00000439928.2
spermatogenesis associated 13
spermatogenesis associated 13
chr11_+_60455839 2.21 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chr2_+_225399684 2.17 ENST00000636099.1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr10_-_59753444 2.13 ENST00000594536.5
ENST00000414264.6
myoregulin
chr6_+_122399621 2.11 ENST00000368455.9
heat shock transcription factor 2
chr19_-_51417619 2.07 ENST00000441969.7
ENST00000339313.10
ENST00000525998.5
ENST00000436984.6
sialic acid binding Ig like lectin 10
chr7_+_123848070 2.06 ENST00000476325.5
hyaluronidase 4
chr4_-_144140712 2.05 ENST00000641688.3
glycophorin A (MNS blood group)
chr8_+_42271289 2.05 ENST00000520810.6
ENST00000520835.7
inhibitor of nuclear factor kappa B kinase subunit beta
chr4_-_89057156 2.03 ENST00000511976.5
ENST00000509094.5
ENST00000264344.10
ENST00000515600.1
family with sequence similarity 13 member A
chr3_-_54928044 2.02 ENST00000273286.6
leucine rich repeats and transmembrane domains 1
chr12_-_57826295 2.01 ENST00000549039.5
CTD small phosphatase 2
chr4_+_119135825 1.99 ENST00000307128.6
myozenin 2
chr7_+_80638662 1.91 ENST00000394788.7
CD36 molecule
chr4_-_144140725 1.90 ENST00000360771.8
glycophorin A (MNS blood group)
chr9_+_68356603 1.90 ENST00000396396.6
phosphoglucomutase 5
chr7_+_80638510 1.85 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr12_+_10307950 1.85 ENST00000543420.5
ENST00000543777.5
killer cell lectin like receptor D1
chr6_-_42722590 1.81 ENST00000230381.7
peripherin 2
chr4_+_40335324 1.72 ENST00000310169.3
cholinergic receptor nicotinic alpha 9 subunit
chr11_+_59511539 1.69 ENST00000641962.1
olfactory receptor family 4 subfamily D member 9
chr5_+_141330494 1.68 ENST00000517417.3
ENST00000378105.4
protocadherin gamma subfamily A, 1
chr12_-_9760893 1.66 ENST00000228434.7
ENST00000536709.1
CD69 molecule
chr7_-_108240049 1.62 ENST00000379022.8
neuronal cell adhesion molecule
chr5_-_151224069 1.61 ENST00000355417.7
coiled-coil domain containing 69
chrY_+_12662344 1.60 ENST00000651177.1
ubiquitin specific peptidase 9 Y-linked
chr3_+_113897470 1.59 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr16_+_32995048 1.57 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr10_-_113664033 1.54 ENST00000359988.4
ENST00000369360.7
ENST00000360478.7
ENST00000369358.8
nebulin related anchoring protein
chr1_+_15684284 1.47 ENST00000375799.8
ENST00000375793.2
pleckstrin homology and RUN domain containing M2
chr3_+_15003912 1.44 ENST00000406272.6
ENST00000617312.4
nuclear receptor subfamily 2 group C member 2
chrX_-_15384402 1.42 ENST00000297904.4
vascular endothelial growth factor D
chr17_+_34255274 1.42 ENST00000580907.5
ENST00000225831.4
C-C motif chemokine ligand 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 54.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
3.1 15.7 GO:0072716 response to actinomycin D(GO:0072716)
3.1 12.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
2.9 11.7 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
2.8 8.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) sarcomerogenesis(GO:0048769)
2.7 16.1 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
2.7 13.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
2.0 16.3 GO:0001887 selenium compound metabolic process(GO:0001887)
1.9 19.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.9 11.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.8 5.5 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.7 5.2 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996)
1.6 6.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.5 7.7 GO:0071109 superior temporal gyrus development(GO:0071109)
1.5 13.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
1.4 7.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.4 4.1 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
1.3 4.0 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.3 6.4 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
1.3 5.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.2 6.1 GO:0090131 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
1.2 11.6 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.1 12.6 GO:0042908 xenobiotic transport(GO:0042908)
1.1 12.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
1.0 6.1 GO:0006064 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) L-ascorbic acid biosynthetic process(GO:0019853) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
1.0 14.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.0 2.9 GO:0001300 chronological cell aging(GO:0001300)
1.0 14.7 GO:0047484 regulation of response to osmotic stress(GO:0047484)
1.0 2.9 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
1.0 10.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.9 4.6 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.8 3.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.8 3.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.7 6.6 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.7 6.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.7 10.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.7 6.3 GO:0042118 endothelial cell activation(GO:0042118)
0.7 2.1 GO:1903347 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.6 8.6 GO:0042574 retinal metabolic process(GO:0042574)
0.6 3.9 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.5 2.1 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.5 6.2 GO:0006824 cobalt ion transport(GO:0006824)
0.5 9.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.5 4.9 GO:0019388 galactose catabolic process(GO:0019388)
0.5 31.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.5 7.6 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.5 1.4 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.5 5.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.5 5.9 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 5.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 1.2 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.4 1.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.4 35.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.4 14.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.4 4.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 14.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.3 10.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 12.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.3 13.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.3 9.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 4.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.3 2.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 6.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.3 20.6 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.2 0.7 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 10.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.2 5.2 GO:0006590 thyroid hormone generation(GO:0006590)
0.2 5.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 3.1 GO:0042737 drug catabolic process(GO:0042737)
0.2 19.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 2.6 GO:0045794 response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.2 3.3 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.2 1.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2 6.9 GO:0006379 mRNA cleavage(GO:0006379)
0.2 32.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 0.7 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2 13.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 1.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 23.8 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.2 5.2 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 4.9 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 3.9 GO:0007608 sensory perception of smell(GO:0007608)
0.1 7.0 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 0.9 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 2.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 5.9 GO:0061615 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 17.2 GO:0002377 immunoglobulin production(GO:0002377)
0.1 6.7 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.1 0.6 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 1.3 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 12.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 1.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.5 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.9 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 11.1 GO:0046718 viral entry into host cell(GO:0046718)
0.1 6.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.8 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.1 5.4 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
0.1 5.9 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 3.0 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 1.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.3 GO:0030578 PML body organization(GO:0030578)
0.1 14.5 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.1 2.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480) positive regulation of IRE1-mediated unfolded protein response(GO:1903896) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.9 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 2.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 2.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.6 GO:0030239 myofibril assembly(GO:0030239)
0.0 3.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.2 GO:0042100 B cell proliferation(GO:0042100)
0.0 0.6 GO:0044849 estrous cycle(GO:0044849)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 2.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 15.1 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 4.5 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 2.0 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 1.7 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.4 GO:2000828 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 1.0 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 1.8 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 4.3 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 1.0 GO:0021987 cerebral cortex development(GO:0021987)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 54.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
3.1 12.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
2.3 7.0 GO:0097679 other organism cytoplasm(GO:0097679)
2.1 14.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
2.0 6.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.0 12.1 GO:0032437 cuticular plate(GO:0032437)
1.5 19.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.3 10.5 GO:0061700 GATOR2 complex(GO:0061700)
1.1 12.7 GO:0016013 syntrophin complex(GO:0016013)
1.1 14.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.0 2.9 GO:0072563 endothelial microparticle(GO:0072563)
0.9 16.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 10.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.8 16.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.7 5.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.6 31.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.5 5.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.5 21.8 GO:0005859 muscle myosin complex(GO:0005859)
0.5 1.5 GO:0005927 muscle tendon junction(GO:0005927)
0.5 2.9 GO:0045298 tubulin complex(GO:0045298)
0.5 6.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.5 7.7 GO:0033010 paranodal junction(GO:0033010)
0.4 7.1 GO:0043235 receptor complex(GO:0043235)
0.4 9.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 5.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 7.8 GO:0043194 axon initial segment(GO:0043194)
0.3 5.0 GO:0097512 cardiac myofibril(GO:0097512)
0.3 11.1 GO:0042629 mast cell granule(GO:0042629)
0.3 6.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.3 3.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 4.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 29.0 GO:0044291 cell-cell contact zone(GO:0044291)
0.3 6.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 4.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 18.1 GO:0005901 caveola(GO:0005901)
0.2 4.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 4.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 6.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 3.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 2.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 5.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 25.5 GO:0030426 growth cone(GO:0030426)
0.1 2.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 44.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 19.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 12.4 GO:0030018 Z disc(GO:0030018)
0.1 21.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 42.1 GO:0009986 cell surface(GO:0009986)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 5.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 7.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.6 GO:0051233 spindle midzone(GO:0051233)
0.1 6.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 11.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 5.2 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 2.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:1990423 RZZ complex(GO:1990423)
0.0 5.8 GO:0072562 blood microparticle(GO:0072562)
0.0 2.0 GO:0030175 filopodium(GO:0030175)
0.0 2.4 GO:0035580 specific granule lumen(GO:0035580)
0.0 4.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 4.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 5.5 GO:0030424 axon(GO:0030424)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 47.2 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0031849 olfactory receptor binding(GO:0031849)
2.9 14.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.9 8.6 GO:0005502 11-cis retinal binding(GO:0005502)
1.7 10.5 GO:0070728 leucine binding(GO:0070728)
1.4 7.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.4 16.3 GO:0008430 selenium binding(GO:0008430)
1.3 6.7 GO:0023024 MHC class I protein complex binding(GO:0023024)
1.3 4.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.3 6.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.2 10.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.2 11.6 GO:0032027 myosin light chain binding(GO:0032027)
1.2 4.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.1 12.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
1.0 5.2 GO:0004447 iodide peroxidase activity(GO:0004447)
1.0 12.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.9 10.3 GO:0031433 telethonin binding(GO:0031433)
0.9 13.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.9 9.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.8 6.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.8 4.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.7 5.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.7 5.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.7 2.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.7 6.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.6 24.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.6 19.1 GO:0005521 lamin binding(GO:0005521)
0.6 54.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.6 10.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.6 10.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.6 2.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.5 31.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.5 6.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.5 15.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5 1.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.5 2.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 3.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 6.2 GO:0031419 cobalamin binding(GO:0031419)
0.4 4.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.4 6.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.4 4.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.4 5.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 2.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.4 2.9 GO:0005534 galactose binding(GO:0005534)
0.4 35.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 2.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 5.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 3.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 29.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 2.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3 2.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 2.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 11.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 1.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 4.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 9.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 47.7 GO:0003823 antigen binding(GO:0003823)
0.2 10.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 23.3 GO:0001618 virus receptor activity(GO:0001618)
0.2 5.3 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 3.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.2 13.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 8.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 5.4 GO:0070034 telomerase RNA binding(GO:0070034) DNA polymerase binding(GO:0070182)
0.2 1.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 4.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 2.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 1.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 3.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.5 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 15.1 GO:0008565 protein transporter activity(GO:0008565)
0.1 3.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 17.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 11.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 9.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.6 GO:0070410 co-SMAD binding(GO:0070410)
0.1 22.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 4.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 4.8 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 12.4 GO:0015631 tubulin binding(GO:0015631)
0.0 3.7 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 10.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 12.3 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 1.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.0 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 5.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 3.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.8 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 54.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 12.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 13.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 5.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 12.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 11.6 PID S1P S1P3 PATHWAY S1P3 pathway
0.2 13.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 5.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 4.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 18.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 10.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 9.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 23.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 11.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 10.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 4.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 13.2 PID AP1 PATHWAY AP-1 transcription factor network
0.1 4.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 12.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 9.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 7.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 5.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 5.9 PID BMP PATHWAY BMP receptor signaling
0.1 2.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 5.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 5.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 5.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 7.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 10.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 ST ADRENERGIC Adrenergic Pathway
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 54.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.9 11.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.7 12.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.7 6.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.5 10.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 19.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 35.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 19.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.4 11.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 14.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 11.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 7.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 13.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3 31.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 5.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 5.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 7.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 4.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 10.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 18.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 10.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 6.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 6.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 4.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 5.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 9.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 12.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 6.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 10.4 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.1 3.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 4.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 6.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.7 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 2.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 7.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.5 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins