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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TFAP2C

Z-value: 1.88

Motif logo

Transcription factors associated with TFAP2C

Gene Symbol Gene ID Gene Info
ENSG00000087510.7 TFAP2C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Chg38_v1_chr20_+_56629296_56629321-0.372.1e-08Click!

Activity profile of TFAP2C motif

Sorted Z-values of TFAP2C motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2C

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_172869 51.02 ENST00000251595.11
ENST00000397806.1
ENST00000484216.1
hemoglobin subunit alpha 2
chr6_+_33075952 32.05 ENST00000418931.7
major histocompatibility complex, class II, DP beta 1
chr21_-_44928824 28.26 ENST00000355153.8
ENST00000397850.6
integrin subunit beta 2
chr14_+_92323154 26.09 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr16_+_176659 24.91 ENST00000320868.9
ENST00000397797.1
hemoglobin subunit alpha 1
chr16_+_85027761 22.55 ENST00000683363.1
KIAA0513
chr9_-_133992312 20.92 ENST00000371850.8
vav guanine nucleotide exchange factor 2
chr15_-_64046322 19.27 ENST00000457488.5
ENST00000612884.4
death associated protein kinase 2
chr10_+_86968432 19.11 ENST00000416348.1
ENST00000372013.8
adipogenesis regulatory factor
chr9_-_96655280 18.94 ENST00000446045.1
ENST00000375234.8
peroxiredoxin like 2C
chr17_-_44915486 18.89 ENST00000638281.1
ENST00000588316.1
ENST00000588735.3
ENST00000639277.1
ENST00000253408.11
ENST00000435360.8
ENST00000586793.6
ENST00000588037.1
ENST00000592320.6
glial fibrillary acidic protein
chr20_-_36951637 18.79 ENST00000646066.1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr2_+_238138661 18.79 ENST00000409223.2
kelch like family member 30
chr20_-_36951665 18.42 ENST00000643918.1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr1_+_192809031 18.29 ENST00000235382.7
regulator of G protein signaling 2
chr15_+_90884429 17.54 ENST00000414248.6
FES proto-oncogene, tyrosine kinase
chr15_+_90884461 17.28 ENST00000559355.5
ENST00000394302.5
FES proto-oncogene, tyrosine kinase
chr2_-_159798043 17.11 ENST00000664982.1
ENST00000259053.6
novel transcript, sense intronic to CD302and LY75-CD302
CD302 molecule
chr7_-_100573865 16.56 ENST00000622764.3
Sin3A associated protein 25
chr16_-_23557331 16.39 ENST00000563232.1
ENST00000449606.7
glutamyl-tRNA synthetase 2, mitochondrial
chr19_+_1067493 16.27 ENST00000586866.5
Rho GTPase activating protein 45
chr19_+_4969105 16.01 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
lysine demethylase 4B
chr20_-_36951701 15.80 ENST00000646673.2
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr7_-_920884 15.67 ENST00000617043.4
ENST00000437486.5
ArfGAP with dual PH domains 1
chr6_+_31586859 15.56 ENST00000433492.5
leukocyte specific transcript 1
chr11_-_61917490 15.26 ENST00000394836.7
RAB3A interacting protein like 1
chr17_-_15999689 14.87 ENST00000399277.6
zinc finger SWIM-type containing 7
chr20_-_36951837 14.29 ENST00000262878.5
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr12_+_10213417 14.23 ENST00000546017.5
ENST00000535576.5
ENST00000539170.5
GABA type A receptor associated protein like 1
chr19_+_50203607 14.20 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr2_-_98936155 14.14 ENST00000428096.5
ENST00000397899.7
ENST00000420294.1
CRACD like
chr15_+_41493860 14.11 ENST00000260386.7
inositol-trisphosphate 3-kinase A
chr11_-_134412234 14.05 ENST00000312527.9
beta-1,3-glucuronyltransferase 1
chr16_+_30407572 13.78 ENST00000319296.10
ENST00000566625.2
zinc finger protein 771
chr9_-_133992281 13.68 ENST00000406606.7
vav guanine nucleotide exchange factor 2
chr2_-_159798234 13.66 ENST00000429078.6
ENST00000553424.5
CD302 molecule
chr22_-_50582785 13.58 ENST00000406938.3
choline kinase beta
chr6_-_6320642 13.37 ENST00000451619.1
ENST00000264870.8
coagulation factor XIII A chain
chr4_+_54657918 13.33 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr12_-_51324138 13.07 ENST00000452142.7
bridging integrator 2
chr14_-_105863862 13.05 ENST00000488476.1
immunoglobulin heavy joining 5
chr20_-_4823597 13.03 ENST00000379400.8
Ras association domain family member 2
chr1_-_153390976 13.00 ENST00000368732.5
ENST00000368733.4
S100 calcium binding protein A8
chr12_-_51324164 12.95 ENST00000615107.6
bridging integrator 2
chr1_-_156248084 12.95 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
progestin and adipoQ receptor family member 6
chr6_+_31587185 12.82 ENST00000376092.7
ENST00000376086.7
ENST00000303757.12
ENST00000376093.6
leukocyte specific transcript 1
chr4_-_687325 12.76 ENST00000503156.5
solute carrier family 49 member 3
chr11_+_114060204 12.75 ENST00000683318.1
zinc finger and BTB domain containing 16
chr6_+_31586835 12.72 ENST00000211921.11
leukocyte specific transcript 1
chr1_-_182391323 12.61 ENST00000642379.1
glutamate-ammonia ligase
chr11_-_47378527 12.59 ENST00000378538.8
Spi-1 proto-oncogene
chr15_+_44288701 12.59 ENST00000299957.11
ENST00000559222.5
ENST00000650436.1
golgi membrane protein 2
chr1_-_156248038 12.49 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr3_-_187745460 12.45 ENST00000406870.7
BCL6 transcription repressor
chr16_-_57284654 12.30 ENST00000613167.4
ENST00000219207.10
ENST00000569059.5
plasmolipin
chr4_-_56656507 12.26 ENST00000381255.7
ENST00000317745.11
ENST00000555760.6
ENST00000556614.6
HOP homeobox
chr1_-_155562693 12.25 ENST00000368346.7
ENST00000392403.8
ENST00000679333.1
ENST00000679133.1
ASH1 like histone lysine methyltransferase
chr6_-_83709019 12.21 ENST00000519779.5
ENST00000369694.6
ENST00000195649.10
synaptosome associated protein 91
chr7_-_112206380 12.21 ENST00000437633.6
ENST00000428084.6
dedicator of cytokinesis 4
chr1_-_156248013 12.19 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr16_-_1475015 12.17 ENST00000382745.9
ENST00000262318.12
ENST00000448525.5
chloride voltage-gated channel 7
chr11_+_17719564 12.09 ENST00000250003.4
myogenic differentiation 1
chr6_+_31586680 12.05 ENST00000339530.8
leukocyte specific transcript 1
chr2_-_174487005 12.04 ENST00000392552.7
ENST00000295500.8
ENST00000614352.4
ENST00000392551.6
G protein-coupled receptor 155
chr10_-_123008784 12.04 ENST00000368886.10
IKAROS family zinc finger 5
chr6_+_31587002 12.02 ENST00000376090.6
leukocyte specific transcript 1
chr10_+_80408503 12.00 ENST00000606162.6
peroxiredoxin like 2A
chr6_-_41733690 12.00 ENST00000419396.6
ENST00000678831.1
ENST00000394283.5
transcription factor EB
chr9_+_136665745 11.97 ENST00000371698.3
EGF like domain multiple 7
chr11_+_121452291 11.88 ENST00000260197.12
sortilin related receptor 1
chr16_+_85027735 11.76 ENST00000258180.7
ENST00000538274.5
KIAA0513
chr5_+_177426701 11.74 ENST00000507633.5
ENST00000393576.7
ENST00000355958.9
ENST00000528793.5
ENST00000512684.1
G protein-coupled receptor kinase 6
chr2_-_43226594 11.70 ENST00000282388.4
ZFP36 ring finger protein like 2
chr11_+_314010 11.63 ENST00000680699.1
ENST00000681938.1
ENST00000679380.1
ENST00000680938.1
ENST00000408968.4
ENST00000681180.1
ENST00000681426.1
ENST00000680696.1
interferon induced transmembrane protein 1
chr11_-_66568524 11.54 ENST00000679160.1
ENST00000678305.1
ENST00000310325.10
ENST00000677896.1
ENST00000677587.1
ENST00000679347.1
ENST00000677005.1
ENST00000678872.1
ENST00000679024.1
ENST00000678471.1
ENST00000524994.6
cathepsin F
chr1_-_27635176 11.50 ENST00000374005.8
FGR proto-oncogene, Src family tyrosine kinase
chr16_+_2537997 11.43 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr12_-_51324652 11.42 ENST00000544402.5
bridging integrator 2
chr2_-_219245465 11.40 ENST00000392089.6
galactosidase beta 1 like
chr15_+_99251362 11.27 ENST00000558879.5
ENST00000301981.8
ENST00000447360.6
ENST00000558172.5
ENST00000561276.5
ENST00000331450.9
leucine rich repeat containing 28
chr6_-_41735557 11.24 ENST00000373033.6
transcription factor EB
chr16_+_81779279 11.23 ENST00000564138.6
phospholipase C gamma 2
chr4_+_2963580 11.14 ENST00000398051.8
ENST00000503518.2
G protein-coupled receptor kinase 4
chr7_-_945799 11.09 ENST00000611167.4
ArfGAP with dual PH domains 1
chr6_+_31587049 11.06 ENST00000376089.6
ENST00000396112.6
leukocyte specific transcript 1
chr22_-_50529990 11.04 ENST00000425169.1
ENST00000487577.5
ENST00000651401.1
ENST00000252029.8
ENST00000395680.6
ENST00000395681.6
ENST00000651196.1
ENST00000650719.1
ENST00000395678.7
thymidine phosphorylase
chr14_-_105856183 11.02 ENST00000637539.2
ENST00000390559.6
immunoglobulin heavy constant mu
chr18_-_49460630 11.01 ENST00000675505.1
ENST00000442713.6
ENST00000269445.10
dymeclin
chr3_+_122325237 10.88 ENST00000264474.4
ENST00000479204.1
cystatin A
chr5_+_73626158 10.88 ENST00000296794.10
ENST00000545377.5
ENST00000509848.5
ENST00000513042.7
Rho guanine nucleotide exchange factor 28
chr9_-_23821275 10.82 ENST00000380110.8
ELAV like RNA binding protein 2
chr16_+_1984182 10.77 ENST00000248114.7
ENST00000569451.1
ENST00000561710.1
growth factor, augmenter of liver regeneration
chr12_-_50167292 10.72 ENST00000547800.2
ENST00000317551.12
ENST00000422340.6
ceramide synthase 5
chr20_-_64079479 10.72 ENST00000395042.2
regulator of G protein signaling 19
chr15_+_83107572 10.70 ENST00000379390.10
ENST00000322019.14
ENST00000565774.5
ENST00000565982.1
transmembrane 6 superfamily member 1
chr3_-_168095885 10.61 ENST00000470487.6
golgi integral membrane protein 4
chr2_-_219245389 10.61 ENST00000428427.1
ENST00000432839.1
ENST00000295759.12
ENST00000424620.1
galactosidase beta 1 like
chr7_-_150341615 10.55 ENST00000223271.8
ENST00000466675.5
ENST00000482669.1
ENST00000467793.5
retinoic acid receptor responder 2
chr1_-_9943314 10.54 ENST00000377223.6
ENST00000377213.1
leucine zipper and CTNNBIP1 domain containing
chr19_-_3028356 10.50 ENST00000586422.5
TLE family member 2, transcriptional corepressor
chr16_-_4538469 10.49 ENST00000588381.1
ENST00000563332.6
cell death inducing p53 target 1
chr14_+_94612383 10.42 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr7_+_150801522 10.38 ENST00000461345.5
transmembrane protein 176A
chr8_+_141128581 10.36 ENST00000519811.6
DENN domain containing 3
chr12_-_47758828 10.36 ENST00000389212.7
ENST00000449771.7
Rap guanine nucleotide exchange factor 3
chr8_-_131040211 10.35 ENST00000377928.7
adenylate cyclase 8
chr22_-_19525369 10.32 ENST00000403084.1
ENST00000413119.2
claudin 5
chr16_+_22814154 10.30 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr1_-_1778399 10.30 ENST00000341426.9
NAD kinase
chr12_+_10212867 10.24 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr8_-_109691766 10.15 ENST00000529190.5
ENST00000422135.5
syntabulin
chr1_-_182953132 10.12 ENST00000367547.8
SHC binding and spindle associated 1 like
chr4_+_2963535 10.07 ENST00000398052.9
G protein-coupled receptor kinase 4
chr13_+_41457543 10.04 ENST00000379359.4
regulator of cell cycle
chr19_-_19643597 9.98 ENST00000587205.1
ENST00000203556.9
GEM interacting protein
chrX_-_13938618 9.93 ENST00000454189.6
glycoprotein M6B
chr11_-_47378494 9.88 ENST00000533030.1
Spi-1 proto-oncogene
chr3_-_9792691 9.85 ENST00000343450.2
transcriptional adaptor 3
chr8_+_22057857 9.85 ENST00000517305.4
ENST00000265800.9
ENST00000517418.5
dematin actin binding protein
chr11_+_72080803 9.85 ENST00000423494.6
ENST00000539587.6
ENST00000536917.2
ENST00000538478.5
ENST00000324866.11
ENST00000643715.1
ENST00000439209.5
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr8_+_141128612 9.84 ENST00000518347.5
ENST00000262585.6
ENST00000520986.5
ENST00000523058.5
ENST00000518668.5
DENN domain containing 3
chr12_-_11171593 9.81 ENST00000535024.6
PRH1-PRR4 readthrough
chr14_+_101561351 9.80 ENST00000510508.4
iodothyronine deiodinase 3
chr20_+_38805686 9.79 ENST00000299824.6
ENST00000373331.2
protein phosphatase 1 regulatory subunit 16B
chr1_-_225924228 9.79 ENST00000343818.11
ENST00000612039.4
ENST00000432920.2
pyrroline-5-carboxylate reductase 2
novel protein
chr5_+_157266079 9.78 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
cytoplasmic FMR1 interacting protein 2
chr10_-_101031095 9.75 ENST00000645349.1
ENST00000619208.6
ENST00000644782.1
ENST00000370215.7
ENST00000646029.1
PDZ domain containing 7
chr17_-_7916280 9.75 ENST00000324348.9
ring finger protein 227
chr12_-_14567714 9.74 ENST00000240617.10
phospholipase B domain containing 1
chr19_+_39342396 9.72 ENST00000602243.5
ENST00000598913.5
ENST00000314471.10
sterile alpha motif domain containing 4B
chr6_-_166956561 9.67 ENST00000366855.10
ribonuclease T2
chr7_-_158829499 9.67 ENST00000275418.13
extended synaptotagmin 2
chr10_-_97334698 9.65 ENST00000371019.4
FRAT regulator of WNT signaling pathway 2
chr19_-_4065732 9.63 ENST00000601588.1
zinc finger and BTB domain containing 7A
chr16_-_75464364 9.61 ENST00000569540.5
ENST00000566594.1
transmembrane protein 170A
novel TMEM170A-CFDP1 readthrough protein
chr17_+_7558774 9.59 ENST00000396545.4
TNF superfamily member 13
chr19_-_13102848 9.59 ENST00000264824.5
LYL1 basic helix-loop-helix family member
chr2_-_206086057 9.59 ENST00000403263.6
INO80 complex subunit D
chr17_+_43780425 9.59 ENST00000449302.8
CFAP97 domain containing 1
chr17_-_76141240 9.58 ENST00000322957.7
forkhead box J1
chr14_-_105644790 9.52 ENST00000641095.1
ENST00000390545.3
immunoglobulin heavy constant gamma 2 (G2m marker)
chr6_-_73452253 9.51 ENST00000370318.5
ENST00000370315.4
cyclic GMP-AMP synthase
chr19_-_8577405 9.50 ENST00000596675.1
ENST00000644032.2
ENST00000613525.4
myosin IF
chr19_+_1067144 9.47 ENST00000313093.7
Rho GTPase activating protein 45
chr1_-_182391363 9.47 ENST00000417584.6
glutamate-ammonia ligase
chr12_+_123671105 9.47 ENST00000680574.1
ENST00000426174.6
ENST00000679504.1
ENST00000303372.7
tectonic family member 2
chr15_+_68930488 9.46 ENST00000310673.4
ENST00000448182.7
ENST00000260364.9
sperm equatorial segment protein 1
NADPH oxidase 5
chr16_+_58249910 9.43 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr18_-_31042733 9.40 ENST00000360428.9
desmocollin 3
chr19_+_49513353 9.39 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr14_+_92513766 9.35 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
Ras and Rab interactor 3
chr7_+_150801695 9.35 ENST00000475536.5
ENST00000468689.2
transmembrane protein 176A
chr15_-_82647503 9.34 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr4_+_75514455 9.28 ENST00000508105.5
ENST00000311638.7
ENST00000380837.7
ENST00000507556.5
ENST00000504190.5
ENST00000507885.5
ENST00000502620.1
ENST00000514480.1
THAP domain containing 6
chr6_+_135181361 9.26 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chr19_-_38229654 9.18 ENST00000412732.5
ENST00000456296.5
double PHD fingers 1
chr19_+_1205761 9.17 ENST00000326873.12
ENST00000586243.5
serine/threonine kinase 11
chr1_-_11805977 9.16 ENST00000376486.3
methylenetetrahydrofolate reductase
chr12_+_76764241 9.07 ENST00000550876.1
zinc finger DHHC-type palmitoyltransferase 17
chr8_+_141391989 9.07 ENST00000520105.5
ENST00000523147.5
ENST00000521578.6
protein tyrosine phosphatase 4A3
chr19_+_1067272 9.06 ENST00000590214.5
Rho GTPase activating protein 45
chr6_-_166956537 9.06 ENST00000508775.6
ribonuclease T2
chr11_-_113875555 9.02 ENST00000003302.8
ENST00000545540.5
ubiquitin specific peptidase 28
chr11_+_17734732 8.99 ENST00000379472.4
ENST00000675775.1
ENST00000265969.8
ENST00000640318.2
ENST00000639325.2
potassium voltage-gated channel subfamily C member 1
chr9_-_136203183 8.96 ENST00000371746.9
LIM homeobox 3
chr3_-_39280432 8.95 ENST00000542107.5
ENST00000435290.1
C-X3-C motif chemokine receptor 1
chr18_+_2846974 8.94 ENST00000254528.4
elastin microfibril interfacer 2
chr11_+_114059755 8.93 ENST00000684295.1
zinc finger and BTB domain containing 16
chr19_+_34481736 8.93 ENST00000590071.7
WT1 interacting protein
chr21_-_34888683 8.90 ENST00000344691.8
ENST00000358356.9
RUNX family transcription factor 1
chr16_+_50152900 8.89 ENST00000436909.8
terminal nucleotidyltransferase 4B
chr11_-_134411854 8.88 ENST00000392580.5
beta-1,3-glucuronyltransferase 1
chr3_+_9793074 8.84 ENST00000397261.8
ENST00000485273.1
ENST00000433034.1
ENST00000397256.5
actin related protein 2/3 complex subunit 4
ARPC4-TTLL3 readthrough
chr7_-_37448845 8.83 ENST00000310758.9
engulfment and cell motility 1
chr14_-_94390650 8.83 ENST00000449399.7
ENST00000404814.8
serpin family A member 1
chr19_-_6720641 8.79 ENST00000245907.11
complement C3
chr17_+_12789457 8.79 ENST00000379672.10
ENST00000340825.7
Rho GTPase activating protein 44
chr19_-_36032799 8.78 ENST00000592017.5
ENST00000360535.9
CAP-Gly domain containing linker protein 3
chr19_-_19628197 8.78 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr10_-_123008687 8.78 ENST00000617859.4
IKAROS family zinc finger 5
chr9_+_87498491 8.76 ENST00000622514.4
death associated protein kinase 1
chr5_-_176630364 8.75 ENST00000310112.7
synuclein beta
chrX_+_153972729 8.71 ENST00000369982.5
transmembrane protein 187
chr2_+_10043524 8.69 ENST00000305883.6
Kruppel like factor 11
chr9_-_136205122 8.67 ENST00000371748.10
LIM homeobox 3
chr1_-_1778790 8.67 ENST00000341991.7
NAD kinase
chr16_-_4416564 8.67 ENST00000572467.5
ENST00000251166.9
ENST00000572044.1
ENST00000571052.5
CORO7-PAM16 readthrough
coronin 7
chr14_-_77271200 8.67 ENST00000298352.5
neuroglobin
chr7_-_130440848 8.65 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
centrosomal protein 41
chr22_+_17084920 8.65 ENST00000612619.1
ENST00000319363.11
interleukin 17 receptor A
chrX_-_1392101 8.64 ENST00000381401.11
solute carrier family 25 member 6
chr16_-_4416621 8.63 ENST00000570645.5
ENST00000574025.5
ENST00000572898.1
ENST00000537233.6
ENST00000571059.5
coronin 7
chrY_-_1392101 8.62 ENST00000381401.11_PAR_Y
solute carrier family 25 member 6
chr2_-_24360445 8.61 ENST00000443927.5
ENST00000406921.7
ENST00000412011.5
ENST00000355123.9
intersectin 2
chr19_-_13906062 8.59 ENST00000591586.5
ENST00000346736.6
break repair meiotic recombinase recruitment factor 1
chr8_-_109691590 8.59 ENST00000532779.5
ENST00000534578.5
syntabulin
chr22_+_35299800 8.58 ENST00000456128.5
ENST00000411850.5
ENST00000425375.5
ENST00000449058.7
target of myb1 membrane trafficking protein
chr11_+_114059702 8.57 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
zinc finger and BTB domain containing 16
chr17_-_81166160 8.55 ENST00000326724.9
apoptosis associated tyrosine kinase
chr12_+_6946468 8.54 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 67.3 GO:0006203 dGTP catabolic process(GO:0006203)
7.4 29.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
6.9 20.8 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
5.8 29.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
5.5 5.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208) dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
5.4 16.3 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
5.4 16.3 GO:0070662 mast cell proliferation(GO:0070662)
5.2 15.6 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
5.2 31.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
5.1 30.5 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
5.0 15.1 GO:0018094 protein polyglycylation(GO:0018094)
4.6 18.3 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
4.5 18.1 GO:0052031 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
4.3 13.0 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
4.3 4.3 GO:0036090 cleavage furrow ingression(GO:0036090)
4.1 4.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
4.0 12.1 GO:0007518 myoblast fate determination(GO:0007518)
4.0 11.9 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
3.9 15.7 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
3.8 19.2 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
3.8 19.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
3.8 11.4 GO:0061011 hepatic duct development(GO:0061011)
3.8 15.2 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
3.8 19.0 GO:0006741 NADP biosynthetic process(GO:0006741)
3.6 21.7 GO:0021523 somatic motor neuron differentiation(GO:0021523)
3.6 14.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
3.5 3.5 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
3.5 10.5 GO:0061760 antifungal innate immune response(GO:0061760)
3.5 10.5 GO:1990108 protein linear deubiquitination(GO:1990108)
3.4 10.1 GO:0060988 lipid tube assembly(GO:0060988)
3.2 12.9 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
3.2 19.1 GO:0072719 cellular response to cisplatin(GO:0072719)
3.1 18.9 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
3.1 6.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
3.1 9.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
3.1 6.2 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
3.1 12.4 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
3.0 29.9 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
3.0 9.0 GO:2000307 tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307)
3.0 8.9 GO:0060005 vestibular reflex(GO:0060005)
2.9 8.8 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
2.9 8.7 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
2.9 17.2 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
2.8 13.9 GO:0071233 cellular response to leucine(GO:0071233)
2.8 8.3 GO:1904430 negative regulation of t-circle formation(GO:1904430)
2.7 8.2 GO:0070625 zymogen granule exocytosis(GO:0070625)
2.7 16.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
2.7 8.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
2.7 13.3 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
2.6 10.5 GO:0099558 maintenance of synapse structure(GO:0099558)
2.6 18.3 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
2.6 2.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
2.6 2.6 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
2.6 13.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
2.6 7.8 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
2.6 15.5 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
2.6 7.8 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
2.6 10.3 GO:0021759 globus pallidus development(GO:0021759)
2.6 33.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
2.6 7.7 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
2.5 7.6 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
2.5 10.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
2.5 2.5 GO:0070316 regulation of G0 to G1 transition(GO:0070316)
2.5 17.2 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
2.4 4.9 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
2.4 12.0 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
2.4 50.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
2.4 2.4 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
2.4 7.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
2.4 16.5 GO:0070560 protein secretion by platelet(GO:0070560)
2.3 44.6 GO:0097320 membrane tubulation(GO:0097320)
2.3 16.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
2.3 7.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
2.3 27.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
2.3 9.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
2.2 2.2 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
2.2 6.7 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
2.2 15.5 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
2.2 8.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
2.2 21.7 GO:0033227 dsRNA transport(GO:0033227)
2.2 2.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
2.2 12.9 GO:0046092 deoxycytidine metabolic process(GO:0046092)
2.1 8.5 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
2.1 10.6 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
2.1 31.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
2.1 44.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
2.1 4.2 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
2.1 6.2 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
2.1 6.2 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
2.1 6.2 GO:0071529 cementum mineralization(GO:0071529)
2.1 6.2 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
2.1 6.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
2.0 8.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020) negative regulation of G-protein coupled receptor internalization(GO:1904021)
2.0 6.1 GO:0019482 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859)
2.0 6.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
2.0 14.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
2.0 6.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
2.0 8.0 GO:0014827 intestine smooth muscle contraction(GO:0014827)
2.0 6.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
2.0 13.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
2.0 5.9 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
1.9 11.7 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
1.9 13.6 GO:1903977 positive regulation of glial cell migration(GO:1903977)
1.9 5.8 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.9 19.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.9 5.8 GO:1990637 response to prolactin(GO:1990637)
1.9 3.8 GO:0043932 ossification involved in bone remodeling(GO:0043932)
1.9 5.7 GO:0019075 virus maturation(GO:0019075)
1.9 5.7 GO:0036146 cellular response to mycotoxin(GO:0036146)
1.9 5.7 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.9 7.6 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.9 9.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.9 5.6 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
1.9 11.3 GO:0006102 isocitrate metabolic process(GO:0006102)
1.8 5.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.8 12.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
1.8 1.8 GO:2001025 positive regulation of response to drug(GO:2001025)
1.8 7.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
1.8 5.5 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.8 5.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.8 10.9 GO:0014807 regulation of somitogenesis(GO:0014807)
1.8 1.8 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
1.8 14.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.8 3.6 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
1.8 1.8 GO:0016139 glycoside catabolic process(GO:0016139)
1.8 5.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.8 3.5 GO:0032762 mast cell cytokine production(GO:0032762)
1.8 5.3 GO:0019046 release from viral latency(GO:0019046)
1.8 7.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
1.8 33.6 GO:0015671 oxygen transport(GO:0015671)
1.8 7.0 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
1.7 10.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
1.7 8.7 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
1.7 5.2 GO:0036048 protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
1.7 3.4 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.7 5.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
1.7 5.1 GO:0008355 olfactory learning(GO:0008355)
1.7 5.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.7 5.1 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
1.7 6.8 GO:0071418 cellular response to amine stimulus(GO:0071418)
1.7 8.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
1.7 8.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.7 6.6 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
1.7 16.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.7 14.9 GO:2001135 regulation of endocytic recycling(GO:2001135)
1.6 1.6 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
1.6 11.4 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
1.6 1.6 GO:0006145 purine nucleobase catabolic process(GO:0006145)
1.6 21.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
1.6 6.5 GO:1900166 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
1.6 6.4 GO:0071110 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
1.6 6.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.6 7.9 GO:0035624 receptor transactivation(GO:0035624)
1.6 11.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
1.6 11.0 GO:0034587 piRNA metabolic process(GO:0034587)
1.6 4.7 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
1.6 1.6 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
1.6 3.1 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
1.6 1.6 GO:1904432 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
1.5 6.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.5 12.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.5 4.6 GO:0048250 mitochondrial iron ion transport(GO:0048250)
1.5 27.6 GO:0097186 amelogenesis(GO:0097186)
1.5 47.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
1.5 9.1 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
1.5 6.0 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.5 1.5 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
1.5 7.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
1.5 11.7 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
1.5 11.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.5 4.4 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
1.5 5.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.5 14.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.5 4.4 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
1.5 2.9 GO:0070055 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
1.4 30.4 GO:0006590 thyroid hormone generation(GO:0006590)
1.4 7.1 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
1.4 12.8 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.4 2.8 GO:0061314 Notch signaling involved in heart development(GO:0061314)
1.4 22.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
1.4 13.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.4 9.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
1.4 4.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
1.4 5.5 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.4 30.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
1.4 22.0 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
1.4 2.7 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
1.4 4.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
1.4 1.4 GO:0033058 directional locomotion(GO:0033058)
1.3 2.7 GO:0060134 prepulse inhibition(GO:0060134)
1.3 5.4 GO:0002357 defense response to tumor cell(GO:0002357)
1.3 4.0 GO:0042412 taurine biosynthetic process(GO:0042412)
1.3 5.3 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
1.3 3.9 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
1.3 2.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.3 20.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
1.3 3.9 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.3 5.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.3 3.8 GO:0001923 B-1 B cell differentiation(GO:0001923)
1.3 6.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
1.3 15.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.3 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
1.2 12.5 GO:0001955 blood vessel maturation(GO:0001955)
1.2 3.7 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.2 1.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
1.2 7.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.2 8.7 GO:0018095 protein polyglutamylation(GO:0018095)
1.2 7.4 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
1.2 17.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.2 6.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.2 9.8 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.2 3.7 GO:0032119 sequestering of zinc ion(GO:0032119)
1.2 2.4 GO:1904180 negative regulation of membrane depolarization(GO:1904180)
1.2 3.6 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
1.2 26.2 GO:0097503 sialylation(GO:0097503)
1.2 4.8 GO:0060010 Sertoli cell fate commitment(GO:0060010)
1.2 5.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.2 9.5 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.2 3.6 GO:0002415 immunoglobulin transcytosis in epithelial cells(GO:0002414) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.2 4.7 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
1.2 2.4 GO:0072014 proximal tubule development(GO:0072014)
1.2 17.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.2 3.5 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
1.2 7.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
1.2 9.2 GO:0042403 thyroid hormone metabolic process(GO:0042403)
1.2 10.4 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822)
1.1 2.3 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
1.1 19.5 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
1.1 3.4 GO:0072300 regulation of metanephric glomerulus development(GO:0072298) positive regulation of metanephric glomerulus development(GO:0072300)
1.1 4.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
1.1 11.2 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
1.1 2.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.1 3.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
1.1 6.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
1.1 2.2 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
1.1 2.2 GO:2000583 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
1.1 3.3 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.1 9.8 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
1.1 11.9 GO:0006657 CDP-choline pathway(GO:0006657)
1.1 5.4 GO:0046208 spermine catabolic process(GO:0046208)
1.1 13.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
1.1 6.5 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
1.1 6.5 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
1.1 4.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.1 12.9 GO:0006516 glycoprotein catabolic process(GO:0006516)
1.1 3.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
1.1 5.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
1.1 15.1 GO:0045792 negative regulation of cell size(GO:0045792)
1.1 1.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.1 2.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
1.1 9.6 GO:1900452 regulation of long term synaptic depression(GO:1900452)
1.1 5.3 GO:0071896 protein localization to adherens junction(GO:0071896)
1.1 6.4 GO:0097338 response to clozapine(GO:0097338)
1.1 4.2 GO:0042631 cellular response to water deprivation(GO:0042631)
1.1 11.6 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
1.1 8.4 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
1.1 15.8 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
1.0 2.1 GO:0030259 lipid glycosylation(GO:0030259)
1.0 17.6 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
1.0 3.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
1.0 38.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.0 15.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
1.0 3.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.0 3.0 GO:0009386 translational attenuation(GO:0009386)
1.0 3.0 GO:0035607 vacuolar phosphate transport(GO:0007037) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.0 11.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.0 5.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
1.0 1.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
1.0 3.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
1.0 9.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.0 89.3 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
1.0 3.0 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
1.0 4.9 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.0 19.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
1.0 2.0 GO:0019230 proprioception(GO:0019230)
1.0 2.9 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
1.0 43.1 GO:0060119 inner ear receptor cell development(GO:0060119)
1.0 9.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.0 3.9 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
1.0 4.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.0 1.9 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
1.0 7.7 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
1.0 8.6 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
1.0 5.7 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.9 10.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.9 14.2 GO:0097062 dendritic spine maintenance(GO:0097062)
0.9 16.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.9 2.8 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.9 1.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.9 2.8 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.9 21.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.9 2.8 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.9 2.8 GO:0061209 cell proliferation involved in mesonephros development(GO:0061209) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.9 9.3 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.9 6.5 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.9 5.5 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
0.9 1.8 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.9 21.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.9 4.6 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.9 3.6 GO:0018343 protein farnesylation(GO:0018343)
0.9 7.2 GO:0048820 hair follicle maturation(GO:0048820)
0.9 1.8 GO:0035995 detection of muscle stretch(GO:0035995)
0.9 3.6 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
0.9 8.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.9 24.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.9 5.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.9 6.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.9 7.8 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.9 5.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.9 3.4 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.9 32.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.9 9.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.9 7.7 GO:0060263 regulation of respiratory burst(GO:0060263)
0.9 6.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.9 2.6 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.8 3.4 GO:0072584 caveolin-mediated endocytosis(GO:0072584)
0.8 1.7 GO:0051866 general adaptation syndrome(GO:0051866)
0.8 4.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.8 2.5 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431)
0.8 1.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.8 10.9 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.8 5.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.8 10.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.8 7.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.8 3.3 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.8 5.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.8 24.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.8 3.3 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.8 4.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.8 3.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.8 8.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.8 10.7 GO:0006004 fucose metabolic process(GO:0006004)
0.8 6.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.8 1.6 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.8 4.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.8 3.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.8 2.5 GO:0006683 galactosylceramide catabolic process(GO:0006683)
0.8 4.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.8 2.5 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.8 5.7 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.8 8.9 GO:1904424 regulation of GTP binding(GO:1904424)
0.8 4.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.8 5.7 GO:0031642 negative regulation of myelination(GO:0031642)
0.8 4.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.8 1.6 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.8 3.2 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.8 1.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.8 13.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.8 7.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.8 7.9 GO:0021633 optic nerve structural organization(GO:0021633)
0.8 3.9 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.8 3.1 GO:1903631 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.8 3.9 GO:0032594 protein transport within lipid bilayer(GO:0032594)
0.8 1.6 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.8 9.4 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.8 10.1 GO:0051593 response to folic acid(GO:0051593)
0.8 27.3 GO:0018149 peptide cross-linking(GO:0018149)
0.8 0.8 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.8 2.3 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.8 15.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.8 1.5 GO:0042940 D-amino acid transport(GO:0042940)
0.8 2.3 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430)
0.8 1.5 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.8 17.7 GO:0045730 respiratory burst(GO:0045730)
0.8 6.1 GO:0006013 mannose metabolic process(GO:0006013)
0.8 6.9 GO:0010996 response to auditory stimulus(GO:0010996)
0.8 5.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.8 2.3 GO:0048318 axial mesoderm development(GO:0048318)
0.8 9.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.8 3.8 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.8 0.8 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.8 3.0 GO:0018879 biphenyl metabolic process(GO:0018879)
0.8 3.8 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.7 6.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.7 2.2 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912) regulation of melanosome transport(GO:1902908)
0.7 2.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.7 3.0 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.7 4.5 GO:0042436 tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.7 2.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.7 2.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.7 5.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.7 2.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231) positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.7 3.6 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.7 2.2 GO:0002384 hepatic immune response(GO:0002384)
0.7 7.2 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.7 0.7 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.7 2.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.7 2.9 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.7 0.7 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.7 5.0 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.7 5.6 GO:0060352 cell adhesion molecule production(GO:0060352)
0.7 6.3 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.7 3.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.7 2.8 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.7 2.1 GO:0031627 telomeric loop formation(GO:0031627)
0.7 2.8 GO:0048304 isotype switching to IgG isotypes(GO:0048291) regulation of isotype switching to IgG isotypes(GO:0048302) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.7 6.2 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.7 2.8 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.7 9.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.7 20.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.7 2.0 GO:1901626 regulation of postsynaptic membrane organization(GO:1901626)
0.7 4.8 GO:0045064 T-helper 2 cell differentiation(GO:0045064)
0.7 2.0 GO:0060214 endocardium formation(GO:0060214)
0.7 20.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.7 5.4 GO:0006477 protein sulfation(GO:0006477)
0.7 6.0 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.7 6.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.7 10.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.7 7.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.7 4.0 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.7 27.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.7 3.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.7 5.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.7 8.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.7 8.5 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.7 2.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.6 4.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.6 3.9 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.6 2.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.6 4.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.6 2.5 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.6 11.4 GO:0010518 positive regulation of phospholipase activity(GO:0010518)
0.6 2.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.6 3.8 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.6 5.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.6 3.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.6 4.4 GO:0006824 cobalt ion transport(GO:0006824)
0.6 2.5 GO:1901838 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.6 7.4 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.6 6.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.6 42.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.6 4.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.6 2.4 GO:0003095 pressure natriuresis(GO:0003095)
0.6 2.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.6 1.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.6 4.2 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.6 4.7 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.6 1.8 GO:0007343 egg activation(GO:0007343) interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.6 5.2 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.6 7.0 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.6 4.6 GO:0032455 nerve growth factor processing(GO:0032455)
0.6 3.4 GO:0051012 microtubule sliding(GO:0051012)
0.6 6.8 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.6 1.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.6 3.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.6 2.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.6 1.1 GO:0043335 protein unfolding(GO:0043335)
0.6 1.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.6 4.4 GO:0051601 exocyst localization(GO:0051601)
0.6 6.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.5 11.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 4.4 GO:0007135 meiosis II(GO:0007135)
0.5 1.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5 7.5 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.5 7.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.5 1.6 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.5 2.1 GO:1903038 negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.5 5.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.5 9.6 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.5 10.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.5 1.1 GO:0061056 sclerotome development(GO:0061056)
0.5 1.6 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.5 14.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.5 21.8 GO:0071625 vocalization behavior(GO:0071625)
0.5 1.0 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.5 3.1 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.5 8.2 GO:0006825 copper ion transport(GO:0006825)
0.5 6.7 GO:0051923 sulfation(GO:0051923)
0.5 1.0 GO:0015793 glycerol transport(GO:0015793)
0.5 1.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.5 10.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.5 4.6 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.5 11.3 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.5 3.5 GO:0002407 dendritic cell chemotaxis(GO:0002407)
0.5 8.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.5 5.0 GO:0071313 cellular response to caffeine(GO:0071313)
0.5 2.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.5 2.0 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.5 5.0 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.5 13.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.5 6.9 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.5 3.5 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.5 6.4 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.5 9.8 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.5 4.9 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.5 3.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.5 9.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.5 2.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.5 4.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.5 1.5 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.5 1.9 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.5 2.9 GO:0015840 urea transport(GO:0015840)
0.5 11.5 GO:0021854 hypothalamus development(GO:0021854)
0.5 3.3 GO:0050932 regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942)
0.5 2.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.5 8.0 GO:0051004 regulation of lipoprotein lipase activity(GO:0051004)
0.5 1.4 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.5 2.8 GO:0006196 AMP catabolic process(GO:0006196)
0.5 2.8 GO:0030204 chondroitin sulfate metabolic process(GO:0030204) chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.5 1.8 GO:0003352 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.5 2.3 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.5 0.5 GO:0021707 cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 9.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.5 3.6 GO:0048266 behavioral response to pain(GO:0048266)
0.5 3.6 GO:1903624 regulation of DNA catabolic process(GO:1903624)
0.5 2.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.5 2.3 GO:0060017 parathyroid gland development(GO:0060017)
0.5 2.7 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.5 0.9 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.5 6.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 4.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.4 4.4 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285)
0.4 1.3 GO:0030432 peristalsis(GO:0030432)
0.4 14.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.4 1.3 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.4 3.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.4 1.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4 2.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 3.0 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.4 6.0 GO:0005513 detection of calcium ion(GO:0005513)
0.4 17.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.4 1.3 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
0.4 0.8 GO:0070253 somatostatin secretion(GO:0070253)
0.4 3.3 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.4 1.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.4 3.7 GO:0030903 notochord development(GO:0030903)
0.4 1.2 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.4 2.9 GO:0071569 protein ufmylation(GO:0071569)
0.4 1.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.4 4.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.4 2.4 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.4 5.6 GO:0010002 cardioblast differentiation(GO:0010002)
0.4 16.9 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.4 5.2 GO:0042574 retinal metabolic process(GO:0042574)
0.4 3.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.4 0.8 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.4 0.8 GO:0033684 regulation of luteinizing hormone secretion(GO:0033684)
0.4 5.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 4.3 GO:0043691 reverse cholesterol transport(GO:0043691)
0.4 20.9 GO:0006953 acute-phase response(GO:0006953)
0.4 3.9 GO:0071481 cellular response to X-ray(GO:0071481)
0.4 31.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.4 2.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.4 1.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.4 3.5 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.4 0.8 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.4 0.8 GO:0002537 nitric oxide production involved in inflammatory response(GO:0002537)
0.4 1.5 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.4 11.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.4 4.9 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.4 3.0 GO:0044065 regulation of respiratory system process(GO:0044065)
0.4 22.4 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.4 2.6 GO:0046449 creatinine metabolic process(GO:0046449)
0.4 5.9 GO:0009437 carnitine metabolic process(GO:0009437)
0.4 13.3 GO:0015701 bicarbonate transport(GO:0015701)
0.4 2.2 GO:0060992 response to fungicide(GO:0060992)
0.4 4.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.4 4.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 3.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.4 1.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.4 2.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4 3.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.4 1.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.4 0.7 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.4 6.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.4 1.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.4 9.6 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.4 2.8 GO:0001573 ganglioside metabolic process(GO:0001573)
0.4 1.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.4 4.6 GO:0043217 myelin maintenance(GO:0043217)
0.4 5.6 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.3 29.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 1.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.3 7.7 GO:0035456 response to interferon-beta(GO:0035456)
0.3 1.0 GO:0035330 regulation of hippo signaling(GO:0035330)
0.3 1.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 1.0 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.3 3.1 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.3 16.6 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.3 0.3 GO:0019532 oxalate transport(GO:0019532)
0.3 3.0 GO:0060292 long term synaptic depression(GO:0060292)
0.3 12.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.3 5.6 GO:0048278 vesicle docking(GO:0048278)
0.3 1.6 GO:0055091 phospholipid homeostasis(GO:0055091)
0.3 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.3 1.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.3 2.3 GO:0043589 skin morphogenesis(GO:0043589)
0.3 4.6 GO:0019228 neuronal action potential(GO:0019228)
0.3 3.3 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.3 10.0 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.3 1.3 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.3 1.2 GO:2000342 negative regulation of interleukin-8 biosynthetic process(GO:0045415) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.3 0.9 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.3 1.8 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 3.0 GO:0006116 NADH oxidation(GO:0006116)
0.3 1.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 3.9 GO:0021924 cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.3 4.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.3 0.9 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.3 3.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.3 2.3 GO:0030091 protein repair(GO:0030091)
0.3 2.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.3 0.6 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.3 0.6 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.3 3.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.3 2.2 GO:0060346 bone trabecula formation(GO:0060346)
0.3 5.0 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.3 2.2 GO:0007413 axonal fasciculation(GO:0007413)
0.3 1.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 6.8 GO:0003170 heart valve development(GO:0003170)
0.3 3.5 GO:2000811 negative regulation of anoikis(GO:2000811)
0.3 1.1 GO:0051697 protein delipidation(GO:0051697)
0.3 6.9 GO:0010107 potassium ion import(GO:0010107)
0.3 4.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.3 2.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 1.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.3 2.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.3 0.3 GO:0048880 sensory system development(GO:0048880)
0.3 3.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 8.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 3.0 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.3 8.1 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.3 1.8 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812) negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.2 2.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.2 1.0 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.2 3.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 14.4 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.2 1.0 GO:0032095 regulation of response to food(GO:0032095)
0.2 9.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 6.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 6.7 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.2 2.8 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.2 1.6 GO:0015886 heme transport(GO:0015886)
0.2 3.7 GO:0043030 regulation of macrophage activation(GO:0043030)
0.2 5.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 1.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 1.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 0.5 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.2 4.6 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.2 5.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 4.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 2.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 4.0 GO:0014047 glutamate secretion(GO:0014047)
0.2 146.1 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.2 1.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 0.7 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.2 2.6 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.2 0.6 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 3.3 GO:0042572 retinol metabolic process(GO:0042572)
0.2 3.9 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 2.0 GO:0006491 N-glycan processing(GO:0006491)
0.2 1.2 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.2 1.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 9.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 2.5 GO:0035640 exploration behavior(GO:0035640)
0.2 7.2 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.2 2.8 GO:0014029 neural crest formation(GO:0014029)
0.2 1.1 GO:0006768 biotin metabolic process(GO:0006768)
0.2 4.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 2.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.2 2.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.2 2.9 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 0.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.2 2.4 GO:0002718 regulation of cytokine production involved in immune response(GO:0002718)
0.2 1.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 0.6 GO:0010922 positive regulation of phosphatase activity(GO:0010922)
0.2 0.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 5.6 GO:0007041 lysosomal transport(GO:0007041)
0.2 0.6 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.2 0.3 GO:0043615 astrocyte cell migration(GO:0043615)
0.2 2.4 GO:2000828 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.1 0.9 GO:0035063 nuclear speck organization(GO:0035063)
0.1 3.4 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 2.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.7 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.9 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.1 1.6 GO:0034311 sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.1 1.1 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 0.4 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 1.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 1.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 15.6 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 0.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.7 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 1.7 GO:0006751 glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.8 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 1.3 GO:0051014 actin filament severing(GO:0051014)
0.1 4.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 3.0 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1 0.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.6 GO:0046463 triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.1 4.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.9 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 1.6 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.1 1.0 GO:0071688 myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 5.7 GO:0006400 tRNA modification(GO:0006400)
0.1 0.9 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.8 GO:0090662 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 1.3 GO:0006465 signal peptide processing(GO:0006465)
0.1 3.0 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.1 0.2 GO:0002016 regulation of blood volume by renin-angiotensin(GO:0002016)
0.1 7.1 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 3.1 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 1.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 1.0 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.9 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.2 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.1 0.5 GO:0072393 microtubule anchoring at centrosome(GO:0034454) microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 1.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.9 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:0034378 chylomicron assembly(GO:0034378)
0.1 2.6 GO:0031295 T cell costimulation(GO:0031295)
0.1 1.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 1.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 4.1 GO:0005977 glycogen metabolic process(GO:0005977)
0.1 0.6 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.7 GO:0097576 vacuole fusion(GO:0097576)
0.1 0.2 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 2.1 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992) negative regulation of urine volume(GO:0035811)
0.0 0.1 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.2 GO:0071467 cellular response to pH(GO:0071467)
0.0 2.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.3 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.0 0.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.3 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.0 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.7 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.3 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.4 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.6 GO:0009583 detection of light stimulus(GO:0009583)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 1.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0006577 amino-acid betaine metabolic process(GO:0006577)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 35.9 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
6.2 24.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
3.9 11.8 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
3.7 11.0 GO:0071753 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
3.4 10.1 GO:0060987 lipid tube(GO:0060987)
3.2 12.8 GO:0005602 complement component C1 complex(GO:0005602)
3.1 15.6 GO:0005797 Golgi medial cisterna(GO:0005797)
2.8 19.6 GO:0032010 phagolysosome(GO:0032010)
2.7 16.4 GO:1990584 cardiac Troponin complex(GO:1990584)
2.6 7.9 GO:0070701 mucus layer(GO:0070701)
2.5 9.8 GO:0002139 stereocilia coupling link(GO:0002139)
2.4 46.1 GO:0042613 MHC class II protein complex(GO:0042613)
2.4 7.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
2.4 19.0 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
2.3 11.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
2.2 13.3 GO:0045298 tubulin complex(GO:0045298)
2.1 8.4 GO:0035363 histone locus body(GO:0035363)
2.1 71.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
2.1 54.2 GO:0001891 phagocytic cup(GO:0001891)
2.0 6.0 GO:0032116 SMC loading complex(GO:0032116)
2.0 14.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
2.0 11.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
2.0 9.8 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.9 11.6 GO:0000137 Golgi cis cisterna(GO:0000137)
1.9 7.7 GO:0071942 XPC complex(GO:0071942)
1.8 5.5 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.8 9.0 GO:0036398 TCR signalosome(GO:0036398)
1.7 19.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.6 3.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
1.6 11.2 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.5 6.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
1.5 22.6 GO:0097433 dense body(GO:0097433)
1.5 1.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
1.4 4.3 GO:0033010 paranodal junction(GO:0033010)
1.4 11.0 GO:0000322 storage vacuole(GO:0000322)
1.4 20.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.3 4.0 GO:0005760 gamma DNA polymerase complex(GO:0005760)
1.3 6.7 GO:0097513 myosin II filament(GO:0097513)
1.3 14.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.3 17.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.3 7.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.3 7.8 GO:0005594 collagen type IX trimer(GO:0005594)
1.3 10.4 GO:0071565 nBAF complex(GO:0071565)
1.3 15.2 GO:0060077 inhibitory synapse(GO:0060077)
1.3 8.8 GO:0033270 paranode region of axon(GO:0033270)
1.2 3.6 GO:0043293 apoptosome(GO:0043293)
1.2 6.0 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
1.2 3.6 GO:1990812 growth cone filopodium(GO:1990812)
1.2 29.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.2 18.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.2 7.0 GO:0097165 nuclear stress granule(GO:0097165)
1.1 6.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.1 10.1 GO:0072687 meiotic spindle(GO:0072687)
1.1 12.1 GO:0030061 mitochondrial crista(GO:0030061)
1.1 10.9 GO:0032059 bleb(GO:0032059)
1.1 3.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
1.1 2.1 GO:0044308 axonal spine(GO:0044308)
1.1 5.3 GO:0072534 perineuronal net(GO:0072534)
1.1 5.3 GO:0019815 B cell receptor complex(GO:0019815)
1.0 4.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.0 2.1 GO:1990761 growth cone lamellipodium(GO:1990761)
1.0 9.2 GO:0042788 polysomal ribosome(GO:0042788)
1.0 10.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.0 24.5 GO:0097386 glial cell projection(GO:0097386)
1.0 11.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.0 12.1 GO:0043083 synaptic cleft(GO:0043083)
1.0 5.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.0 35.0 GO:0030673 axolemma(GO:0030673)
1.0 4.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.9 2.8 GO:0030312 external encapsulating structure(GO:0030312)
0.9 13.6 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.9 21.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.9 30.4 GO:0032590 dendrite membrane(GO:0032590)
0.9 11.6 GO:0042583 chromaffin granule(GO:0042583)
0.9 3.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.8 5.0 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.8 14.0 GO:0000145 exocyst(GO:0000145)
0.8 5.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.8 4.9 GO:0001940 male pronucleus(GO:0001940)
0.8 12.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.8 40.2 GO:0042571 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.8 19.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.8 11.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.8 5.4 GO:1990745 EARP complex(GO:1990745)
0.8 19.2 GO:0042627 chylomicron(GO:0042627)
0.8 6.9 GO:0071953 elastic fiber(GO:0071953)
0.8 5.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.8 3.0 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.7 4.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.7 16.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.7 7.3 GO:0060171 stereocilium membrane(GO:0060171)
0.7 15.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 5.0 GO:0031256 leading edge membrane(GO:0031256)
0.7 4.9 GO:0032280 symmetric synapse(GO:0032280)
0.7 4.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.7 2.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.7 13.0 GO:0036038 MKS complex(GO:0036038)
0.7 4.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.7 6.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.7 5.4 GO:0061700 GATOR2 complex(GO:0061700)
0.7 2.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.7 4.6 GO:0043196 varicosity(GO:0043196)
0.7 32.8 GO:0016235 aggresome(GO:0016235)
0.7 19.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.7 3.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 3.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 7.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.6 2.5 GO:0036128 CatSper complex(GO:0036128)
0.6 1.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.6 5.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.6 8.3 GO:0000124 SAGA complex(GO:0000124)
0.6 24.7 GO:0048786 presynaptic active zone(GO:0048786)
0.6 4.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.6 11.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.6 4.5 GO:0000813 ESCRT I complex(GO:0000813)
0.6 10.1 GO:0043218 compact myelin(GO:0043218)
0.6 2.8 GO:0032444 activin responsive factor complex(GO:0032444)
0.5 8.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.5 1.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.5 3.8 GO:0033391 chromatoid body(GO:0033391)
0.5 2.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.5 13.4 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.5 5.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.5 3.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.5 2.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.5 2.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.5 7.8 GO:0030478 actin cap(GO:0030478)
0.5 3.1 GO:1990769 proximal neuron projection(GO:1990769)
0.5 5.7 GO:0042588 zymogen granule(GO:0042588)
0.5 3.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.5 4.6 GO:0045180 basal cortex(GO:0045180)
0.5 22.4 GO:0001533 cornified envelope(GO:0001533)
0.5 2.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.5 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 1.5 GO:0055087 Ski complex(GO:0055087)
0.5 35.9 GO:0005902 microvillus(GO:0005902)
0.5 2.9 GO:0060091 kinocilium(GO:0060091)
0.5 2.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.5 4.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.5 30.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5 10.0 GO:0005652 nuclear lamina(GO:0005652)
0.5 1.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.5 9.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.5 3.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.5 7.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5 4.1 GO:0044194 cytolytic granule(GO:0044194)
0.5 27.2 GO:0031594 neuromuscular junction(GO:0031594)
0.5 3.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.5 11.9 GO:0031527 filopodium membrane(GO:0031527)
0.5 3.6 GO:0031045 dense core granule(GO:0031045)
0.5 5.0 GO:0042611 MHC protein complex(GO:0042611)
0.4 23.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 6.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 2.2 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.4 7.1 GO:0035102 PRC1 complex(GO:0035102)
0.4 2.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 2.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 3.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 7.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.4 1.7 GO:0033186 CAF-1 complex(GO:0033186)
0.4 5.9 GO:0005883 neurofilament(GO:0005883)
0.4 35.8 GO:0036064 ciliary basal body(GO:0036064)
0.4 15.9 GO:0045095 keratin filament(GO:0045095)
0.4 10.0 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.4 27.8 GO:0034707 chloride channel complex(GO:0034707)
0.4 4.5 GO:0005955 calcineurin complex(GO:0005955)
0.4 4.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 48.0 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.4 3.3 GO:0035976 AP1 complex(GO:0035976)
0.4 8.2 GO:0001772 immunological synapse(GO:0001772)
0.4 2.8 GO:0005683 U7 snRNP(GO:0005683)
0.4 7.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 9.0 GO:0034451 centriolar satellite(GO:0034451)
0.4 5.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 4.9 GO:0000815 ESCRT III complex(GO:0000815)
0.4 5.8 GO:0000974 Prp19 complex(GO:0000974)
0.4 3.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.4 51.1 GO:0032587 ruffle membrane(GO:0032587)
0.4 1.4 GO:0097443 sorting endosome(GO:0097443)
0.4 25.3 GO:0005796 Golgi lumen(GO:0005796)
0.4 3.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 1.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 1.4 GO:0043194 axon initial segment(GO:0043194)
0.3 7.2 GO:0045177 apical part of cell(GO:0045177)
0.3 1.0 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.3 1.0 GO:0033167 ARC complex(GO:0033167)
0.3 3.0 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.3 16.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.3 2.0 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.3 14.7 GO:0016460 myosin II complex(GO:0016460)
0.3 16.0 GO:0031201 SNARE complex(GO:0031201)
0.3 3.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 19.0 GO:0042734 presynaptic membrane(GO:0042734)
0.3 13.0 GO:0043235 receptor complex(GO:0043235)
0.3 1.8 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.3 3.9 GO:0071437 invadopodium(GO:0071437)
0.3 42.2 GO:0043202 lysosomal lumen(GO:0043202)
0.3 0.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.3 13.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3 15.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.3 2.4 GO:0070652 HAUS complex(GO:0070652)
0.3 13.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.3 18.1 GO:0005776 autophagosome(GO:0005776)
0.2 27.8 GO:0031901 early endosome membrane(GO:0031901)
0.2 37.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 0.7 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.2 2.6 GO:0000786 nucleosome(GO:0000786)
0.2 2.6 GO:0030897 HOPS complex(GO:0030897)
0.2 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.2 148.1 GO:0000139 Golgi membrane(GO:0000139)
0.2 6.1 GO:0016459 myosin complex(GO:0016459)
0.2 4.5 GO:0030658 transport vesicle membrane(GO:0030658)
0.2 2.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 11.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 12.9 GO:0035580 specific granule lumen(GO:0035580)
0.2 25.8 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.8 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.2 3.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 8.5 GO:0031526 brush border membrane(GO:0031526)
0.2 3.8 GO:0097546 ciliary base(GO:0097546)
0.2 10.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 1.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 2.6 GO:0031906 late endosome lumen(GO:0031906)
0.2 1.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 56.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2 22.7 GO:0072562 blood microparticle(GO:0072562)
0.2 29.5 GO:0060076 excitatory synapse(GO:0060076)
0.2 3.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 2.6 GO:0005642 annulate lamellae(GO:0005642)
0.2 3.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 0.5 GO:0016938 kinesin I complex(GO:0016938)
0.2 2.9 GO:0070461 SAGA-type complex(GO:0070461)
0.1 1.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.1 GO:0032797 SMN complex(GO:0032797)
0.1 0.7 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.7 GO:1902560 GMP reductase complex(GO:1902560)
0.1 4.5 GO:0016592 mediator complex(GO:0016592)
0.1 7.0 GO:0005581 collagen trimer(GO:0005581)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 1.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 2.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.6 GO:0071141 SMAD protein complex(GO:0071141)
0.1 5.7 GO:0035579 specific granule membrane(GO:0035579)
0.1 0.3 GO:0042581 specific granule(GO:0042581)
0.1 16.8 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 1.5 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 45.6 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 12.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
16.8 67.3 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567)
7.4 29.7 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
7.1 21.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
6.3 25.3 GO:0033897 ribonuclease T2 activity(GO:0033897)
5.7 22.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
5.1 35.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
5.0 15.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
5.0 15.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
4.9 14.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
4.8 28.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
4.6 13.8 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
4.2 25.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703) beta-adrenergic receptor kinase activity(GO:0047696)
3.9 15.7 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
3.9 15.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
3.5 10.5 GO:0032093 SAM domain binding(GO:0032093)
3.4 17.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
3.4 20.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
3.3 9.9 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
3.3 9.8 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
3.2 16.0 GO:0004803 transposase activity(GO:0004803)
3.1 18.8 GO:0070728 leucine binding(GO:0070728)
3.1 34.1 GO:0051525 NFAT protein binding(GO:0051525)
2.8 17.0 GO:0030172 troponin C binding(GO:0030172)
2.8 11.2 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
2.8 11.1 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
2.7 8.2 GO:0031687 A2A adenosine receptor binding(GO:0031687)
2.7 16.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
2.7 24.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
2.6 31.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
2.6 7.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
2.6 54.1 GO:0050811 GABA receptor binding(GO:0050811)
2.6 18.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
2.6 10.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
2.5 7.6 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
2.5 7.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
2.5 2.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
2.5 7.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
2.5 19.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.4 19.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
2.4 7.2 GO:0004967 glucagon receptor activity(GO:0004967)
2.4 26.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.4 11.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.4 11.8 GO:0043208 glycosphingolipid binding(GO:0043208)
2.3 9.4 GO:0019770 IgG receptor activity(GO:0019770)
2.3 11.7 GO:0004351 glutamate decarboxylase activity(GO:0004351)
2.3 16.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
2.3 44.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
2.3 11.6 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
2.3 11.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
2.3 9.2 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
2.3 11.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
2.3 13.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
2.2 20.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
2.2 33.6 GO:0005344 oxygen transporter activity(GO:0005344)
2.2 8.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
2.2 2.2 GO:0050682 AF-2 domain binding(GO:0050682)
2.2 4.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
2.1 8.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
2.1 6.2 GO:0019959 interleukin-8 binding(GO:0019959)
2.1 14.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
2.0 6.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
2.0 28.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
2.0 14.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
2.0 22.1 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
2.0 8.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
2.0 9.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.9 7.8 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
1.9 3.9 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
1.9 17.2 GO:0004565 beta-galactosidase activity(GO:0004565)
1.9 7.6 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
1.9 7.5 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
1.9 9.3 GO:0004905 type I interferon receptor activity(GO:0004905)
1.8 12.9 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
1.8 14.7 GO:0005000 vasopressin receptor activity(GO:0005000)
1.8 5.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
1.8 9.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.8 5.4 GO:0017129 triglyceride binding(GO:0017129)
1.8 5.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.8 8.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.7 21.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.7 5.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
1.7 5.2 GO:0005502 11-cis retinal binding(GO:0005502)
1.7 8.7 GO:0004522 ribonuclease A activity(GO:0004522)
1.7 5.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.7 5.2 GO:0036055 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
1.7 10.3 GO:0008420 CTD phosphatase activity(GO:0008420)
1.7 11.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.7 5.1 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
1.7 39.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.7 5.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
1.7 6.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.6 8.2 GO:0070573 metallodipeptidase activity(GO:0070573)
1.6 13.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.6 90.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
1.6 9.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.6 19.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.6 14.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.6 6.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.6 6.4 GO:0004079 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
1.6 9.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.6 14.2 GO:0045125 sphingosine-1-phosphate receptor activity(GO:0038036) bioactive lipid receptor activity(GO:0045125)
1.5 10.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.5 7.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.5 6.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
1.5 7.5 GO:0048039 ubiquinone binding(GO:0048039)
1.5 6.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.5 7.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.5 5.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.5 11.9 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.5 8.8 GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811)
1.5 5.8 GO:0004920 interleukin-10 receptor activity(GO:0004920)
1.4 7.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.4 5.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.4 45.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.4 5.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.4 11.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
1.4 9.6 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
1.4 6.8 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.4 5.4 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
1.3 18.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
1.3 9.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.3 4.0 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
1.3 3.9 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
1.3 22.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
1.3 6.5 GO:0004771 sterol esterase activity(GO:0004771)
1.3 10.3 GO:0009008 DNA-methyltransferase activity(GO:0009008)
1.3 22.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.3 11.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
1.3 3.8 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
1.2 10.0 GO:0042608 T cell receptor binding(GO:0042608)
1.2 23.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.2 4.8 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
1.2 59.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
1.2 4.8 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
1.2 8.3 GO:0043199 sulfate binding(GO:0043199)
1.2 7.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
1.2 18.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.2 3.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.1 9.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
1.1 7.8 GO:0032395 MHC class II receptor activity(GO:0032395)
1.1 5.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.1 14.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.1 3.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.1 5.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
1.1 5.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.1 5.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) azole transmembrane transporter activity(GO:1901474)
1.1 10.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.1 4.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.1 7.4 GO:0000405 bubble DNA binding(GO:0000405)
1.1 54.9 GO:0001784 phosphotyrosine binding(GO:0001784)
1.0 2.1 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
1.0 16.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.0 5.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.0 5.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.0 14.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
1.0 14.1 GO:0019957 C-C chemokine binding(GO:0019957)
1.0 4.0 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
1.0 14.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.0 9.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.0 3.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
1.0 3.0 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
1.0 18.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
1.0 5.9 GO:0023029 MHC class Ib protein binding(GO:0023029)
1.0 3.9 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.0 8.8 GO:0016595 glutamate binding(GO:0016595)
1.0 28.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.0 11.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.9 32.2 GO:0042605 peptide antigen binding(GO:0042605)
0.9 5.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.9 4.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.9 8.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.9 2.8 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.9 6.5 GO:0000150 recombinase activity(GO:0000150)
0.9 3.7 GO:0035939 microsatellite binding(GO:0035939)
0.9 2.7 GO:0005174 CD40 receptor binding(GO:0005174)
0.9 6.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.9 7.1 GO:0004645 phosphorylase activity(GO:0004645)
0.9 5.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.9 24.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.9 3.6 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.9 4.4 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.9 7.1 GO:0043426 MRF binding(GO:0043426)
0.9 2.6 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.9 24.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.9 7.9 GO:0004969 histamine receptor activity(GO:0004969)
0.9 7.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.9 22.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.9 5.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.9 7.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.9 3.5 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.9 7.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.9 9.5 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.9 3.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.8 24.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.8 11.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.8 5.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.8 3.3 GO:0034648 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.8 2.5 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.8 2.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.8 23.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.8 2.5 GO:0004336 galactosylceramidase activity(GO:0004336)
0.8 2.5 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.8 44.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.8 2.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.8 2.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.8 13.4 GO:0043274 phospholipase binding(GO:0043274)
0.8 3.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.8 3.1 GO:0004341 gluconolactonase activity(GO:0004341)
0.8 3.9 GO:0070051 fibrinogen binding(GO:0070051)
0.8 2.3 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.8 3.8 GO:0004447 iodide peroxidase activity(GO:0004447)
0.8 4.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.8 4.5 GO:0004359 glutaminase activity(GO:0004359)
0.8 4.5 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.8 3.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.7 8.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.7 13.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.7 2.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.7 8.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.7 4.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.7 2.2 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) ciliary neurotrophic factor binding(GO:0070119)
0.7 1.5 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.7 4.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.7 8.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.7 6.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.7 2.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.7 4.9 GO:0008417 fucosyltransferase activity(GO:0008417)
0.7 9.0 GO:1903136 cuprous ion binding(GO:1903136)
0.7 5.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.7 6.9 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.7 6.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.7 2.7 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.7 10.1 GO:0034452 dynactin binding(GO:0034452)
0.7 4.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.7 3.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.7 0.7 GO:0070644 vitamin D response element binding(GO:0070644)
0.6 3.9 GO:1990405 protein antigen binding(GO:1990405)
0.6 5.8 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.6 1.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.6 1.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.6 10.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.6 8.2 GO:0070700 BMP receptor binding(GO:0070700)
0.6 3.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.6 9.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.6 1.8 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.6 3.0 GO:0009881 photoreceptor activity(GO:0009881)
0.6 1.8 GO:0045322 unmethylated CpG binding(GO:0045322)
0.6 6.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.6 2.4 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.6 4.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.6 4.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.6 3.6 GO:0050780 dopamine receptor binding(GO:0050780)
0.6 1.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.6 32.4 GO:0030507 spectrin binding(GO:0030507)
0.6 12.3 GO:0004707 MAP kinase activity(GO:0004707)
0.6 2.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.6 8.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.6 2.3 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.6 3.5 GO:0043237 laminin-1 binding(GO:0043237)
0.6 3.4 GO:0004875 complement receptor activity(GO:0004875)
0.6 5.1 GO:0009374 biotin binding(GO:0009374)
0.6 9.5 GO:0031005 filamin binding(GO:0031005)
0.6 2.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.6 6.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6 60.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.6 6.1 GO:0019864 IgG binding(GO:0019864)
0.6 1.7 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.5 8.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 2.7 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.5 1.6 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.5 12.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 1.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.5 1.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.5 3.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.5 40.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.5 9.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.5 2.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.5 14.7 GO:0005521 lamin binding(GO:0005521)
0.5 10.5 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.5 2.6 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.5 8.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.5 17.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.5 3.6 GO:0003680 AT DNA binding(GO:0003680)
0.5 1.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.5 12.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.5 4.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.5 15.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.5 5.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.5 5.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.5 6.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.5 3.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.5 2.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.5 5.0 GO:0019841 retinol binding(GO:0019841)
0.5 2.0 GO:0004952 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) dopamine neurotransmitter receptor activity(GO:0004952)
0.5 1.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.5 5.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.5 3.8 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.5 2.8 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.5 6.5 GO:0045159 myosin II binding(GO:0045159)
0.5 2.8 GO:0017040 ceramidase activity(GO:0017040)
0.5 5.1 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.5 3.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.5 3.2 GO:0050733 RS domain binding(GO:0050733)
0.5 10.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.5 11.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.5 5.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.5 6.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.5 4.5 GO:0015250 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.4 4.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.4 6.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 19.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.4 1.8 GO:0001855 complement component C4b binding(GO:0001855)
0.4 1.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.4 3.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.4 3.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.4 1.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.4 6.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.4 1.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 1.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.4 14.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4 8.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 14.8 GO:0071837 HMG box domain binding(GO:0071837)
0.4 2.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.4 1.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.4 7.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.4 1.6 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.4 2.4 GO:0050051 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.4 4.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.4 2.4 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.4 3.2 GO:0089720 caspase binding(GO:0089720)
0.4 6.0 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.4 5.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 3.2 GO:0045499 chemorepellent activity(GO:0045499)
0.4 19.6 GO:0030276 clathrin binding(GO:0030276)
0.4 5.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.4 0.8 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.4 4.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 4.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.4 6.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4 1.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.4 11.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 8.0 GO:0071949 FAD binding(GO:0071949)
0.4 106.7 GO:0005096 GTPase activator activity(GO:0005096)
0.4 23.4 GO:0070412 R-SMAD binding(GO:0070412)
0.4 16.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.4 1.1 GO:0080084 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.4 1.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.4 9.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.4 10.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4 42.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 18.5 GO:0005254 chloride channel activity(GO:0005254)
0.3 1.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 39.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.3 6.5 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.3 6.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.3 2.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 8.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.3 2.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 9.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 1.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 5.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3 5.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 1.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.3 0.9 GO:0000182 rDNA binding(GO:0000182)
0.3 0.9 GO:0032427 GBD domain binding(GO:0032427) apolipoprotein receptor binding(GO:0034190) apolipoprotein A-I receptor binding(GO:0034191)
0.3 0.9 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.3 1.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 7.9 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 1.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.3 1.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 5.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 3.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 1.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.3 0.6 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.3 5.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 1.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.3 8.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 2.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 2.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 1.7 GO:0001515 opioid peptide activity(GO:0001515)
0.3 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 4.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 5.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 0.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 7.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 5.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 12.0 GO:0005158 insulin receptor binding(GO:0005158)
0.3 2.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 3.2 GO:0015926 glucosidase activity(GO:0015926)
0.3 9.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 3.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 3.5 GO:0016805 dipeptidase activity(GO:0016805)
0.3 1.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 4.0 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.3 2.1 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.3 8.3 GO:0001671 ATPase activator activity(GO:0001671)
0.3 3.8 GO:0005522 profilin binding(GO:0005522)
0.3 2.8 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.3 2.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 6.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.3 0.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181)
0.3 1.5 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.3 2.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 4.0 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 1.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 9.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 24.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 4.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.0 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.2 11.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 0.7 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 2.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 2.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 4.1 GO:0030552 cAMP binding(GO:0030552)
0.2 0.9 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 8.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 1.8 GO:0031433 telethonin binding(GO:0031433)
0.2 2.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 5.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 4.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 3.0 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.6 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.2 2.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 1.9 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 1.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 2.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 0.6 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
0.2 0.6 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 5.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 256.0 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2 1.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 2.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2 31.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 1.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 3.1 GO:0050321 tau-protein kinase activity(GO:0050321) ATPase regulator activity(GO:0060590)
0.2 6.2 GO:0030332 cyclin binding(GO:0030332)
0.2 1.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.2 1.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 2.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 7.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 4.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 2.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 21.4 GO:0005516 calmodulin binding(GO:0005516)
0.2 27.3 GO:0005261 cation channel activity(GO:0005261)
0.2 37.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 2.2 GO:0031432 titin binding(GO:0031432)
0.2 0.8 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 0.5 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.9 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 0.7 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.1 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.7 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 6.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 1.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 1.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 2.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.1 GO:0010181 FMN binding(GO:0010181)
0.1 0.7 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 2.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 3.9 GO:0000049 tRNA binding(GO:0000049)
0.1 0.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 1.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.7 GO:0008374 O-acyltransferase activity(GO:0008374)
0.1 0.7 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.7 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.9 GO:0052742 phosphatidylinositol kinase activity(GO:0052742)
0.1 1.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 1.8 GO:0042805 actinin binding(GO:0042805)
0.1 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.7 GO:0031404 chloride ion binding(GO:0031404)
0.1 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 1.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 2.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 1.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 1.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.4 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 7.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
1.6 20.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
1.5 164.0 PID IL4 2PATHWAY IL4-mediated signaling events
1.5 52.6 PID EPO PATHWAY EPO signaling pathway
1.4 5.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
1.4 2.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
1.2 6.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
1.1 6.7 PID IL5 PATHWAY IL5-mediated signaling events
1.1 8.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
1.0 5.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
1.0 23.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.9 28.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.9 43.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.9 7.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.8 8.5 PID S1P S1P3 PATHWAY S1P3 pathway
0.8 44.2 PID ARF6 PATHWAY Arf6 signaling events
0.8 12.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.8 26.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.7 8.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.7 5.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.7 4.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6 10.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.6 11.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 40.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.6 6.8 PID BMP PATHWAY BMP receptor signaling
0.6 6.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.6 7.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.6 22.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.5 2.2 ST STAT3 PATHWAY STAT3 Pathway
0.5 7.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5 5.5 PID BCR 5PATHWAY BCR signaling pathway
0.5 18.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.5 23.5 PID LKB1 PATHWAY LKB1 signaling events
0.5 5.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.5 34.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.5 29.4 PID FGF PATHWAY FGF signaling pathway
0.5 13.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.5 13.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.5 8.2 PID IFNG PATHWAY IFN-gamma pathway
0.5 8.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.4 3.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.4 15.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 17.6 PID CD40 PATHWAY CD40/CD40L signaling
0.4 6.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.4 16.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.4 27.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.4 3.5 PID IL27 PATHWAY IL27-mediated signaling events
0.4 6.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 8.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.4 1.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.4 2.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.3 2.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 5.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 10.8 PID ALK1 PATHWAY ALK1 signaling events
0.3 6.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 10.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 3.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 9.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 8.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 2.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3 6.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 7.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 11.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.3 3.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 3.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 14.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 9.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 5.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 1.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 6.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 5.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 2.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 6.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 3.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 6.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 2.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 1.6 ST GA13 PATHWAY G alpha 13 Pathway
0.2 8.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 14.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 6.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 13.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 21.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.7 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.3 PID FOXO PATHWAY FoxO family signaling
0.1 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 1.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 2.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 5.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.0 PID P73PATHWAY p73 transcription factor network
0.1 1.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 4.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 4.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 2.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
2.1 41.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.9 46.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
1.7 32.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.5 7.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.5 2.9 REACTOME SIGNALLING TO RAS Genes involved in Signalling to RAS
1.4 18.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
1.3 3.9 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
1.3 18.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.3 1.3 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
1.2 17.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.2 2.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
1.2 18.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.2 1.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
1.2 13.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.1 20.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
1.1 19.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
1.1 2.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
1.1 26.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
1.1 8.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.0 59.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
1.0 3.0 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
1.0 21.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.0 12.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
1.0 13.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
1.0 3.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.9 10.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.9 19.6 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.9 20.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.9 2.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.9 14.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.9 13.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.9 2.7 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.9 34.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.9 23.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.9 4.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.9 15.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.8 13.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.8 1.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.8 17.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.8 26.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.8 17.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.8 18.9 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.8 34.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.8 24.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.8 12.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.7 28.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 33.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.7 24.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.7 8.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.6 15.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.6 57.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.6 6.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.6 12.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.6 21.4 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.6 29.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.6 11.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.6 6.4 REACTOME OPSINS Genes involved in Opsins
0.6 5.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.6 24.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.6 38.5 REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.6 7.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.6 76.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.6 7.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.5 5.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.5 8.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.5 9.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.5 15.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.5 18.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.5 8.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 22.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.4 6.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 3.4 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.4 0.8 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.4 9.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.4 9.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.4 25.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 4.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.4 4.2 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.4 4.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.4 11.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.4 4.0 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.4 5.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 5.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 7.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.4 7.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 2.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 10.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.3 10.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 3.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 9.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 15.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 9.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 5.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.3 6.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 14.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 7.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 15.7 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.3 2.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.3 8.6 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.3 7.0 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.3 1.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 7.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 5.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 6.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 1.7 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 2.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 2.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 2.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 5.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 6.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 0.9 REACTOME PI 3K CASCADE Genes involved in PI-3K cascade
0.2 10.3 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.2 1.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 1.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 4.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 11.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 3.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 3.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 4.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 15.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 6.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 1.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.2 2.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 1.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 3.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 14.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 0.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 3.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 3.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 3.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 6.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 12.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 7.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 7.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 4.7 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 1.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 2.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 22.2 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 1.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 2.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 3.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 19.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 8.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 1.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 10.0 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling
0.0 1.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME SIGNALING BY NOTCH Genes involved in Signaling by NOTCH
0.0 2.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation