GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
TP53 Links Ensembl NCBI GeneCards UniProt	ENSG00000141510.18	TP53

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TP53	hg38_v1_chr17_-_7687427_7687538	0.39	3.3e-09	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr6_-_30744537 Show fit	18.08	ENST00000259874.6 ENST00000376377.2	IER3 Links Ensembl NCBI GeneCards UniProt Show fit	immediate early response 3
chr17_-_41525326 Show fit	17.08	ENST00000593096.1	KRT19 Links Ensembl NCBI GeneCards UniProt Show fit	keratin 19
chr1_+_224356852 Show fit	16.48	ENST00000366858.7 ENST00000366857.9 ENST00000465271.6 ENST00000366856.3	CNIH4 Links Ensembl NCBI GeneCards UniProt Show fit	cornichon family AMPA receptor auxiliary protein 4
chr15_-_64162965 Show fit	15.17	ENST00000300026.4 ENST00000681397.1 ENST00000681658.1	PPIB Links Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase B
chr7_+_116526277 Show fit	15.01	ENST00000393468.1 ENST00000393467.1	CAV1 Links Ensembl NCBI GeneCards UniProt Show fit	caveolin 1
chr1_+_156082563 Show fit	14.34	ENST00000368301.6	LMNA Links Ensembl NCBI GeneCards UniProt Show fit	lamin A/C
chr7_+_99374722 Show fit	13.90	ENST00000418347.6 ENST00000429246.6 ENST00000417330.6 ENST00000431816.6 ENST00000458033.6 ENST00000451682.5 ENST00000427217.6 ENST00000646101.2	ARPC1B Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2/3 complex subunit 1B
chr10_-_125158704 Show fit	13.87	ENST00000531469.5	CTBP2 Links Ensembl NCBI GeneCards UniProt Show fit	C-terminal binding protein 2
chr1_+_203861575 Show fit	13.32	ENST00000414487.7	SNRPE Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide E
chr1_-_53945661 Show fit	13.20	ENST00000194214.10	HSPB11 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chr20_+_36605734 Show fit	12.74	ENST00000344795.8 ENST00000373852.9	RAB5IF Links Ensembl NCBI GeneCards UniProt Show fit	RAB5 interacting factor
chr6_-_138107412 Show fit	12.35	ENST00000421351.4	PERP Links Ensembl NCBI GeneCards UniProt Show fit	p53 apoptosis effector related to PMP22
chr20_+_36605820 Show fit	12.23	ENST00000342422.3	RAB5IF Links Ensembl NCBI GeneCards UniProt Show fit	RAB5 interacting factor
chr12_+_56104527 Show fit	12.09	ENST00000552766.5 ENST00000303305.11	PA2G4 Links Ensembl NCBI GeneCards UniProt Show fit	proliferation-associated 2G4
chr1_-_209652329 Show fit	11.98	ENST00000367030.7 ENST00000356082.9	LAMB3 Links Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 3
chr6_+_36676455 Show fit	11.88	ENST00000615513.4	CDKN1A Links Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 1A
chr7_+_99374675 Show fit	11.78	ENST00000645391.1 ENST00000455009.6	ARPC1B Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2/3 complex subunit 1B
chr12_-_6342020 Show fit	11.52	ENST00000540022.5 ENST00000536194.1	TNFRSF1A Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 1A
chr4_-_10116724 Show fit	11.14	ENST00000502702.5	WDR1 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 1
chr6_+_36676489 Show fit	11.14	ENST00000448526.6	CDKN1A Links Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 1A
chr16_+_51553436 Show fit	11.14	ENST00000565308.2	HNRNPA1P48 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein A1 pseudogene 48
chr15_-_22980334 Show fit	10.36	ENST00000610365.4 ENST00000617928.5 ENST00000611832.4	CYFIP1 Links Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic FMR1 interacting protein 1
chr3_+_184176949 Show fit	9.91	ENST00000432591.5 ENST00000431779.5 ENST00000621863.4	AP2M1 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 2 subunit mu 1
chr11_-_65540610 Show fit	9.86	ENST00000532661.5	LTBP3 Links Ensembl NCBI GeneCards UniProt Show fit	latent transforming growth factor beta binding protein 3
chr15_-_63156774 Show fit	9.71	ENST00000462430.5	RPS27L Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S27 like
chr2_+_84971093 Show fit	9.63	ENST00000456682.1 ENST00000409785.9	KCMF1 Links Ensembl NCBI GeneCards UniProt Show fit	potassium channel modulatory factor 1
chrX_+_71254781 Show fit	9.47	ENST00000677446.1	NONO Links Ensembl NCBI GeneCards UniProt Show fit	non-POU domain containing octamer binding
chr20_-_5119945 Show fit	9.34	ENST00000379143.10	PCNA Links Ensembl NCBI GeneCards UniProt Show fit	proliferating cell nuclear antigen
chr7_+_157138912 Show fit	9.31	ENST00000611269.4 ENST00000348165.10	UBE3C Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin protein ligase E3C
chr22_-_36528897 Show fit	9.29	ENST00000405442.5 ENST00000402116.2	EIF3D Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit D
chr22_-_36529136 Show fit	8.96	ENST00000216190.13 ENST00000455547.5	EIF3D Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit D
chr3_+_184176778 Show fit	8.95	ENST00000439647.5	AP2M1 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 2 subunit mu 1
chrX_-_155458620 Show fit	8.69	ENST00000622749.2	F8A3 Links Ensembl NCBI GeneCards UniProt Show fit	coagulation factor VIII associated 3
chrX_+_155382095 Show fit	8.66	ENST00000369505.5	F8A2 Links Ensembl NCBI GeneCards UniProt Show fit	coagulation factor VIII associated 2
chr20_-_49188360 Show fit	8.58	ENST00000371828.7 ENST00000340954.11 ENST00000347458.9 ENST00000360426.8 ENST00000371792.5 ENST00000371802.5 ENST00000437404.2	STAU1 Links Ensembl NCBI GeneCards UniProt Show fit	staufen double-stranded RNA binding protein 1
chr16_-_31094549 Show fit	8.51	ENST00000394971.7	VKORC1 Links Ensembl NCBI GeneCards UniProt Show fit	vitamin K epoxide reductase complex subunit 1
chr1_+_42682954 Show fit	8.39	ENST00000436427.1	YBX1 Links Ensembl NCBI GeneCards UniProt Show fit	Y-box binding protein 1
chr18_+_9913979 Show fit	8.23	ENST00000400000.7 ENST00000340541.4	VAPA Links Ensembl NCBI GeneCards UniProt Show fit	VAMP associated protein A
chr7_+_101127095 Show fit	8.09	ENST00000223095.5	SERPINE1 Links Ensembl NCBI GeneCards UniProt Show fit	serpin family E member 1
chr17_+_78214186 Show fit	8.04	ENST00000301633.8 ENST00000350051.8 ENST00000374948.6 ENST00000590449.1	BIRC5 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 5
chr11_-_64317528 Show fit	7.98	ENST00000308774.6 ENST00000544844.6	TRMT112 Links Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase subunit 11-2
chr20_-_49188323 Show fit	7.94	ENST00000371856.7	STAU1 Links Ensembl NCBI GeneCards UniProt Show fit	staufen double-stranded RNA binding protein 1
chrX_+_40580894 Show fit	7.84	ENST00000636409.1 ENST00000637327.1 ENST00000637526.1 ENST00000638153.1 ENST00000378438.9 ENST00000636970.1 ENST00000636196.1 ENST00000636251.1 ENST00000637482.1 ENST00000636580.2 ENST00000423649.2 ENST00000636287.1	ATP6AP2 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting accessory protein 2
chr4_-_10116324 Show fit	7.80	ENST00000508079.1	WDR1 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 1
chr20_+_35172046 Show fit	7.79	ENST00000216968.5	PROCR Links Ensembl NCBI GeneCards UniProt Show fit	protein C receptor
chr9_-_135961310 Show fit	7.75	ENST00000371756.4	UBAC1 Links Ensembl NCBI GeneCards UniProt Show fit	UBA domain containing 1
chrX_+_154886355 Show fit	7.73	ENST00000610495.2	F8A1 Links Ensembl NCBI GeneCards UniProt Show fit	coagulation factor VIII associated 1
chr12_-_6342066 Show fit	7.34	ENST00000162749.7 ENST00000440083.6	TNFRSF1A Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 1A
chr15_-_34343112 Show fit	7.10	ENST00000557912.1 ENST00000328848.6	NOP10 Links Ensembl NCBI GeneCards UniProt Show fit	NOP10 ribonucleoprotein
chr5_+_163437569 Show fit	7.08	ENST00000512163.5 ENST00000393929.5 ENST00000510097.5 ENST00000340828.7 ENST00000511490.4 ENST00000510664.5	CCNG1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin G1
chrX_+_40581035 Show fit	7.02	ENST00000447485.6	ATP6AP2 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting accessory protein 2
chr19_+_38374758 Show fit	6.98	ENST00000585598.1 ENST00000602911.5 ENST00000592561.5	PSMD8 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 8
chr12_-_122227449 Show fit	6.93	ENST00000650715.1	DIABLO Links Ensembl NCBI GeneCards UniProt Show fit	diablo IAP-binding mitochondrial protein
chr18_+_59899988 Show fit	6.79	ENST00000316660.7 ENST00000269518.9	PMAIP1 Links Ensembl NCBI GeneCards UniProt Show fit	phorbol-12-myristate-13-acetate-induced protein 1
chr1_-_15809348 Show fit	6.79	ENST00000483273.2	UQCRHL Links Ensembl NCBI GeneCards UniProt Show fit	ubiquinol-cytochrome c reductase hinge protein like
chr12_+_12813316 Show fit	6.69	ENST00000352940.8 ENST00000358007.7 ENST00000544400.1	DDX47 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 47
chr12_-_122227491 Show fit	6.52	ENST00000475784.1 ENST00000645606.1	ENSG00000284934.2 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr2_+_112645930 Show fit	6.32	ENST00000272542.8	SLC20A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 20 member 1
chr5_+_73498408 Show fit	6.30	ENST00000335895.12 ENST00000678135.1 ENST00000380591.7 ENST00000677654.1 ENST00000507081.6	BTF3 Links Ensembl NCBI GeneCards UniProt Show fit	basic transcription factor 3
chr20_-_1393074 Show fit	6.26	ENST00000614856.2 ENST00000678408.1 ENST00000618612.5 ENST00000439640.5 ENST00000381719.8 ENST00000677533.1	FKBP1A Links Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 1A
chr2_+_197500398 Show fit	6.23	ENST00000604458.1	HSPE1-MOB4 Links Ensembl NCBI GeneCards UniProt Show fit	HSPE1-MOB4 readthrough
chr11_+_65181687 Show fit	6.13	ENST00000527739.5 ENST00000526966.5 ENST00000533129.5 ENST00000524773.5	CAPN1 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 1
chr11_+_65181920 Show fit	6.01	ENST00000279247.11 ENST00000532285.1 ENST00000534373.5	CAPN1 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 1
chr16_+_2496032 Show fit	5.90	ENST00000564543.1	ENSG00000260272.1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr11_+_65181194 Show fit	5.58	ENST00000533820.5	CAPN1 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 1
chrX_+_152917830 Show fit	5.48	ENST00000318529.12	ZNF185 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 185 with LIM domain
chr7_+_48088596 Show fit	5.43	ENST00000416681.5 ENST00000331803.8 ENST00000432131.5	UPP1 Links Ensembl NCBI GeneCards UniProt Show fit	uridine phosphorylase 1
chr1_-_156020789 Show fit	5.41	ENST00000531917.5 ENST00000480567.5 ENST00000526212.2 ENST00000529008.5 ENST00000496742.5 ENST00000295702.9	SSR2 Links Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor subunit 2
chr9_+_113275642 Show fit	5.38	ENST00000374199.9 ENST00000374198.5	PRPF4 Links Ensembl NCBI GeneCards UniProt Show fit	pre-mRNA processing factor 4
chr11_-_73982830 Show fit	5.37	ENST00000536983.5 ENST00000663595.2 ENST00000310473.9	UCP2 Links Ensembl NCBI GeneCards UniProt Show fit	uncoupling protein 2
chrX_+_56563569 Show fit	5.37	ENST00000338222.7	UBQLN2 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquilin 2
chr6_-_100881281 Show fit	5.33	ENST00000369143.2 ENST00000369162.7 ENST00000324723.10 ENST00000522650.5	ASCC3 Links Ensembl NCBI GeneCards UniProt Show fit	activating signal cointegrator 1 complex subunit 3
chr15_-_65185299 Show fit	5.19	ENST00000300107.7	CLPX Links Ensembl NCBI GeneCards UniProt Show fit	caseinolytic mitochondrial matrix peptidase chaperone subunit X
chr9_+_78297143 Show fit	5.18	ENST00000347159.6	PSAT1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoserine aminotransferase 1
chr10_-_47484081 Show fit	5.13	ENST00000583448.2 ENST00000583874.5 ENST00000585281.6	ANXA8 Links Ensembl NCBI GeneCards UniProt Show fit	annexin A8
chr10_+_46375645 Show fit	5.10	ENST00000622769.4	ANXA8L1 Links Ensembl NCBI GeneCards UniProt Show fit	annexin A8 like 1
chr16_-_31094727 Show fit	5.05	ENST00000300851.10 ENST00000394975.3	VKORC1 Links Ensembl NCBI GeneCards UniProt Show fit	vitamin K epoxide reductase complex subunit 1
chr11_-_3057386 Show fit	4.95	ENST00000529772.5 ENST00000278224.13 ENST00000380525.9	CARS1 Links Ensembl NCBI GeneCards UniProt Show fit	cysteinyl-tRNA synthetase 1
chr22_-_17774412 Show fit	4.89	ENST00000342111.9 ENST00000622694.5	BID Links Ensembl NCBI GeneCards UniProt Show fit	BH3 interacting domain death agonist
chr9_+_78297117 Show fit	4.84	ENST00000376588.4	PSAT1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoserine aminotransferase 1
chr14_+_24232921 Show fit	4.80	ENST00000557854.5 ENST00000399440.7 ENST00000559104.5 ENST00000456667.7	GMPR2 Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase 2
chr10_+_46375721 Show fit	4.79	ENST00000616785.1 ENST00000611655.1 ENST00000619162.5	ENSG00000285402.1 Links Ensembl NCBI GeneCards UniProt Show fit ANXA8L1 Links Ensembl NCBI GeneCards UniProt Show fit	novel transcript annexin A8 like 1
chr22_-_37019434 Show fit	4.67	ENST00000249042.8 ENST00000403892.7	TST Links Ensembl NCBI GeneCards UniProt Show fit	thiosulfate sulfurtransferase
chr1_+_32179665 Show fit	4.63	ENST00000373610.8	TXLNA Links Ensembl NCBI GeneCards UniProt Show fit	taxilin alpha
chr19_+_41860236 Show fit	4.63	ENST00000601492.5 ENST00000600467.6 ENST00000598742.6 ENST00000221975.6 ENST00000598261.2	RPS19 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S19
chr8_-_23069012 Show fit	4.59	ENST00000347739.3 ENST00000276431.9	TNFRSF10B Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 10b
chr10_-_47484133 Show fit	4.51	ENST00000583911.5 ENST00000611843.4	ANXA8 Links Ensembl NCBI GeneCards UniProt Show fit	annexin A8
chr18_+_12947982 Show fit	4.46	ENST00000262124.15	SEH1L Links Ensembl NCBI GeneCards UniProt Show fit	SEH1 like nucleoporin
chr16_-_18433412 Show fit	4.46	ENST00000620440.4	NOMO2 Links Ensembl NCBI GeneCards UniProt Show fit	NODAL modulator 2
chr1_-_53945567 Show fit	4.45	ENST00000371378.6	HSPB11 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chr9_-_179008 Show fit	4.41	ENST00000613508.4 ENST00000382447.8 ENST00000382389.5 ENST00000377447.7 ENST00000382393.2 ENST00000314367.14 ENST00000356521.8 ENST00000377400.8	CBWD1 Links Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 1
chr20_-_1393045 Show fit	4.40	ENST00000400137.9 ENST00000381715.4	FKBP1A Links Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 1A
chr2_+_197500371 Show fit	4.40	ENST00000409468.1 ENST00000233893.10	HSPE1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family E (Hsp10) member 1
chr10_+_46375619 Show fit	4.37	ENST00000584982.7 ENST00000613703.4	ANXA8L1 Links Ensembl NCBI GeneCards UniProt Show fit	annexin A8 like 1
chr16_-_31094890 Show fit	4.32	ENST00000532364.1 ENST00000529564.1 ENST00000319788.11 ENST00000354895.4	ENSG00000255439.6 Links Ensembl NCBI GeneCards UniProt Show fit VKORC1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein, VKORC1 and PRSS53 readthrough vitamin K epoxide reductase complex subunit 1
chr4_+_41935423 Show fit	4.31	ENST00000504986.6	TMEM33 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 33
chr11_-_83285965 Show fit	4.30	ENST00000529073.5 ENST00000529611.5	CCDC90B Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 90B
chr1_-_54053394 Show fit	4.30	ENST00000452421.5 ENST00000420738.5 ENST00000440019.5	TMEM59 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 59
chr22_-_17774482 Show fit	4.25	ENST00000399765.5 ENST00000614949.4 ENST00000399767.6	BID Links Ensembl NCBI GeneCards UniProt Show fit	BH3 interacting domain death agonist
chr1_-_93180377 Show fit	4.22	ENST00000370282.8	TMED5 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane p24 trafficking protein 5
chr1_-_156741067 Show fit	4.04	ENST00000361531.6 ENST00000412846.5	MRPL24 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L24
chr11_-_47378391 Show fit	4.03	ENST00000227163.8	SPI1 Links Ensembl NCBI GeneCards UniProt Show fit	Spi-1 proto-oncogene
chr1_-_53945584 Show fit	3.89	ENST00000371377.3	HSPB11 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chr19_+_19385815 Show fit	3.87	ENST00000494516.6 ENST00000360315.7	GATAD2A Links Ensembl NCBI GeneCards UniProt Show fit	GATA zinc finger domain containing 2A
chr7_+_140696696 Show fit	3.84	ENST00000247866.9 ENST00000464566.5	NDUFB2 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B2
chr1_+_32180044 Show fit	3.80	ENST00000373609.1	TXLNA Links Ensembl NCBI GeneCards UniProt Show fit	taxilin alpha
chr3_-_113746185 Show fit	3.70	ENST00000616174.1	NAA50 Links Ensembl NCBI GeneCards UniProt Show fit	N-alpha-acetyltransferase 50, NatE catalytic subunit
chr1_+_1033987 Show fit	3.68	ENST00000651234.1 ENST00000652369.1	AGRN Links Ensembl NCBI GeneCards UniProt Show fit	agrin
chr19_+_926001 Show fit	3.58	ENST00000263620.8	ARID3A Links Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 3A
chr13_+_75760431 Show fit	3.58	ENST00000321797.12	LMO7 Links Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr12_+_53501578 Show fit	3.52	ENST00000552817.5 ENST00000394357.6	TARBP2 Links Ensembl NCBI GeneCards UniProt Show fit	TARBP2 subunit of RISC loading complex
chr7_+_140696665 Show fit	3.49	ENST00000476279.5 ENST00000461457.1 ENST00000465506.5	NDUFB2 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B2
chr2_-_234497035 Show fit	3.47	ENST00000390645.2 ENST00000339728.6	ARL4C Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 4C
chr20_-_34955635 Show fit	3.47	ENST00000644793.1 ENST00000642498.1 ENST00000646735.1 ENST00000644608.1 ENST00000651619.1	GSS Links Ensembl NCBI GeneCards UniProt Show fit	glutathione synthetase
chr1_-_156741124 Show fit	3.39	ENST00000368211.8	MRPL24 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L24
chr1_+_27879638 Show fit	3.39	ENST00000456990.1	THEMIS2 Links Ensembl NCBI GeneCards UniProt Show fit	thymocyte selection associated family member 2
chr17_-_63896621 Show fit	3.16	ENST00000453363.7	CSH1 Links Ensembl NCBI GeneCards UniProt Show fit	chorionic somatomammotropin hormone 1
chr11_-_47378494 Show fit	3.14	ENST00000533030.1	SPI1 Links Ensembl NCBI GeneCards UniProt Show fit	Spi-1 proto-oncogene
chr12_+_53501272 Show fit	3.12	ENST00000552857.5 ENST00000266987.7 ENST00000547064.5	TARBP2 Links Ensembl NCBI GeneCards UniProt Show fit	TARBP2 subunit of RISC loading complex
chr10_+_68901258 Show fit	3.10	ENST00000373585.8	DDX50 Links Ensembl NCBI GeneCards UniProt Show fit	DExD-box helicase 50
chr12_+_53500885 Show fit	3.07	ENST00000456234.6	TARBP2 Links Ensembl NCBI GeneCards UniProt Show fit	TARBP2 subunit of RISC loading complex
chr7_+_140697144 Show fit	3.06	ENST00000476470.5 ENST00000471136.5	NDUFB2 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B2
chr2_-_157876301 Show fit	3.06	ENST00000434821.7	ACVR1 Links Ensembl NCBI GeneCards UniProt Show fit	activin A receptor type 1
chr2_-_74529670 Show fit	3.03	ENST00000377526.4	AUP1 Links Ensembl NCBI GeneCards UniProt Show fit	AUP1 lipid droplet regulating VLDL assembly factor
chr12_-_14567714 Show fit	3.02	ENST00000240617.10	PLBD1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipase B domain containing 1
chr14_+_101761786 Show fit	3.02	ENST00000422945.6 ENST00000554442.5 ENST00000556260.6 ENST00000328724.9 ENST00000557268.5	PPP2R5C Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit B'gamma
chr17_+_78214286 Show fit	2.95	ENST00000592734.5 ENST00000587746.5	BIRC5 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 5
chr4_+_2536630 Show fit	2.87	ENST00000637812.2	FAM193A Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 193 member A
chr11_-_47378527 Show fit	2.87	ENST00000378538.8	SPI1 Links Ensembl NCBI GeneCards UniProt Show fit	Spi-1 proto-oncogene
chr4_+_41935114 Show fit	2.81	ENST00000508448.5 ENST00000513702.5 ENST00000325094.9	TMEM33 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 33
chr1_-_93180261 Show fit	2.80	ENST00000370280.1 ENST00000479918.5	TMED5 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane p24 trafficking protein 5
chr19_-_1605425 Show fit	2.78	ENST00000589880.1 ENST00000591899.8 ENST00000585671.2	UQCR11 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquinol-cytochrome c reductase, complex III subunit XI
chr17_+_76376581 Show fit	2.74	ENST00000591651.5 ENST00000545180.5	SPHK1 Links Ensembl NCBI GeneCards UniProt Show fit	sphingosine kinase 1
chr17_-_63873676 Show fit	2.66	ENST00000613718.3 ENST00000392886.7 ENST00000345366.8 ENST00000336844.9 ENST00000560142.5	CSH2 Links Ensembl NCBI GeneCards UniProt Show fit	chorionic somatomammotropin hormone 2
chr14_-_36521149 Show fit	2.65	ENST00000518149.5	NKX2-1 Links Ensembl NCBI GeneCards UniProt Show fit	NK2 homeobox 1
chr11_-_65859282 Show fit	2.58	ENST00000526975.1 ENST00000531413.5 ENST00000525451.6	CFL1 Links Ensembl NCBI GeneCards UniProt Show fit	cofilin 1
chr6_+_36130484 Show fit	2.57	ENST00000373766.9 ENST00000211287.9	MAPK13 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 13
chr2_+_168456215 Show fit	2.55	ENST00000392687.4 ENST00000305747.11	CERS6 Links Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 6
chr1_-_12618198 Show fit	2.52	ENST00000616661.5	DHRS3 Links Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase 3
chr11_-_75306688 Show fit	2.51	ENST00000532525.1	ARRB1 Links Ensembl NCBI GeneCards UniProt Show fit	arrestin beta 1
chr19_+_57363469 Show fit	2.45	ENST00000282282.4 ENST00000543226.2 ENST00000596755.1 ENST00000597658.1	ZNF547 Links Ensembl NCBI GeneCards UniProt Show fit TRAPPC2B Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000268133.1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 547 trafficking protein particle complex 2B novel protein
chr7_+_140696956 Show fit	2.44	ENST00000460088.5 ENST00000472695.5	NDUFB2 Links Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B2
chr1_+_26826682 Show fit	2.38	ENST00000374142.9	ZDHHC18 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 18
chr6_+_52420107 Show fit	2.35	ENST00000636489.1 ENST00000637089.1 ENST00000637353.1 ENST00000637263.1	EFHC1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain containing 1
chr10_+_90871946 Show fit	2.30	ENST00000413330.5 ENST00000371703.8 ENST00000277882.7	RPP30 Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease P/MRP subunit p30
chr5_-_132490750 Show fit	2.29	ENST00000437654.6 ENST00000245414.9 ENST00000680139.1 ENST00000680352.1 ENST00000679440.1 ENST00000680903.1	IRF1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 1
chr11_-_69819410 Show fit	2.27	ENST00000334134.4	FGF3 Links Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor 3
chr6_+_24402908 Show fit	2.25	ENST00000274747.11 ENST00000443868.6 ENST00000378386.8 ENST00000378353.5	MRS2 Links Ensembl NCBI GeneCards UniProt Show fit	magnesium transporter MRS2
chr18_-_36829154 Show fit	2.22	ENST00000614939.4 ENST00000610723.4	TPGS2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr17_-_63918817 Show fit	2.22	ENST00000458650.6 ENST00000351388.8 ENST00000342364.8 ENST00000617086.1 ENST00000323322.10 ENST00000392824.8	GH1 Links Ensembl NCBI GeneCards UniProt Show fit CSHL1 Links Ensembl NCBI GeneCards UniProt Show fit	growth hormone 1 chorionic somatomammotropin hormone like 1
chr4_-_128288791 Show fit	2.13	ENST00000613358.4 ENST00000520121.6	PGRMC2 Links Ensembl NCBI GeneCards UniProt Show fit	progesterone receptor membrane component 2
chr14_-_106235582 Show fit	2.03	ENST00000390607.2	IGHV3-21 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-21
chr16_+_2029636 Show fit	2.02	ENST00000561844.5	SLC9A3R2 Links Ensembl NCBI GeneCards UniProt Show fit	SLC9A3 regulator 2
chr10_-_87094761 Show fit	1.96	ENST00000684338.1 ENST00000684201.1 ENST00000277865.5	GLUD1 Links Ensembl NCBI GeneCards UniProt Show fit	glutamate dehydrogenase 1
chr12_+_6828377 Show fit	1.96	ENST00000290510.10	P3H3 Links Ensembl NCBI GeneCards UniProt Show fit	prolyl 3-hydroxylase 3
chr16_-_10942443 Show fit	1.96	ENST00000570440.2 ENST00000331808.5	DEXI Links Ensembl NCBI GeneCards UniProt Show fit	Dexi homolog
chr7_+_23105747 Show fit	1.94	ENST00000322275.9 ENST00000339077.10	KLHL7 Links Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 7
chr11_-_108593738 Show fit	1.91	ENST00000525344.5 ENST00000265843.9	EXPH5 Links Ensembl NCBI GeneCards UniProt Show fit	exophilin 5
chr2_-_18560616 Show fit	1.90	ENST00000381249.4	RDH14 Links Ensembl NCBI GeneCards UniProt Show fit	retinol dehydrogenase 14
chr4_-_158723355 Show fit	1.87	ENST00000307720.4	PPID Links Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase D
chr22_+_46674593 Show fit	1.86	ENST00000408031.1	GRAMD4 Links Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 4
chr7_+_43583091 Show fit	1.86	ENST00000319357.6	STK17A Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 17a
chr17_-_63446168 Show fit	1.77	ENST00000584031.5 ENST00000392976.5	CYB561 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome b561
chr3_-_45995807 Show fit	1.73	ENST00000535325.5 ENST00000296137.7	FYCO1 Links Ensembl NCBI GeneCards UniProt Show fit	FYVE and coiled-coil domain autophagy adaptor 1
chr16_-_58198059 Show fit	1.70	ENST00000262506.8	CSNK2A2 Links Ensembl NCBI GeneCards UniProt Show fit	casein kinase 2 alpha 2
chr19_+_48954850 Show fit	1.68	ENST00000345358.12 ENST00000539787.2 ENST00000415969.6 ENST00000354470.7 ENST00000506183.5 ENST00000391871.4 ENST00000293288.12	BAX Links Ensembl NCBI GeneCards UniProt Show fit	BCL2 associated X, apoptosis regulator
chr7_+_23106267 Show fit	1.62	ENST00000409689.5 ENST00000410047.1	KLHL7 Links Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 7
chr5_+_218241 Show fit	1.62	ENST00000617470.4 ENST00000504309.5 ENST00000510361.5 ENST00000264932.11	SDHA Links Ensembl NCBI GeneCards UniProt Show fit	succinate dehydrogenase complex flavoprotein subunit A
chr19_+_3136026 Show fit	1.62	ENST00000262958.4	GNA15 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha 15
chr9_-_14314567 Show fit	1.61	ENST00000397579.6	NFIB Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr1_-_54053461 Show fit	1.58	ENST00000371341.5	TMEM59 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 59
chr6_+_52420332 Show fit	1.58	ENST00000636107.1 ENST00000371068.11 ENST00000636702.1 ENST00000635996.1 ENST00000636379.1	EFHC1 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain containing 1
chr1_-_2526585 Show fit	1.55	ENST00000378466.9 ENST00000435556.8	PANK4 Links Ensembl NCBI GeneCards UniProt Show fit	pantothenate kinase 4 (inactive)
chr2_-_241617464 Show fit	1.54	ENST00000402545.5 ENST00000402136.5	THAP4 Links Ensembl NCBI GeneCards UniProt Show fit	THAP domain containing 4
chrX_+_100644183 Show fit	1.50	ENST00000640889.1 ENST00000373004.5	SRPX2 Links Ensembl NCBI GeneCards UniProt Show fit	sushi repeat containing protein X-linked 2
chr10_+_87095169 Show fit	1.47	ENST00000298784.5 ENST00000298786.5	SHLD2 Links Ensembl NCBI GeneCards UniProt Show fit	shieldin complex subunit 2
chr7_-_100641507 Show fit	1.47	ENST00000431692.5 ENST00000223051.8	TFR2 Links Ensembl NCBI GeneCards UniProt Show fit	transferrin receptor 2
chr16_+_527698 Show fit	1.40	ENST00000219611.7 ENST00000562370.5 ENST00000568988.5	CAPN15 Links Ensembl NCBI GeneCards UniProt Show fit	calpain 15
chr3_+_149812682 Show fit	1.39	ENST00000344229.7	RNF13 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 13
chr12_+_108562579 Show fit	1.38	ENST00000311893.14 ENST00000535729.5 ENST00000431221.6 ENST00000547005.5 ENST00000392807.8 ENST00000539593.1	ISCU Links Ensembl NCBI GeneCards UniProt Show fit	iron-sulfur cluster assembly enzyme
chr14_+_92513766 Show fit	1.35	ENST00000216487.12 ENST00000620541.4 ENST00000557762.1	RIN3 Links Ensembl NCBI GeneCards UniProt Show fit	Ras and Rab interactor 3
chr12_+_3077355 Show fit	1.33	ENST00000537971.5 ENST00000011898.10 ENST00000649909.1	TSPAN9 Links Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 9
chr6_-_30742203 Show fit	1.32	ENST00000416018.5 ENST00000445853.5 ENST00000413165.5 ENST00000418160.5	FLOT1 Links Ensembl NCBI GeneCards UniProt Show fit	flotillin 1
chr11_-_77411883 Show fit	1.26	ENST00000528203.5 ENST00000528592.5 ENST00000528633.1 ENST00000529248.5	PAK1 Links Ensembl NCBI GeneCards UniProt Show fit	p21 (RAC1) activated kinase 1
chr18_-_36828730 Show fit	1.13	ENST00000587382.5	TPGS2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr10_-_103452356 Show fit	1.11	ENST00000260743.10	CALHM2 Links Ensembl NCBI GeneCards UniProt Show fit	calcium homeostasis modulator family member 2
chr20_-_23637933 Show fit	1.09	ENST00000398411.5	CST3 Links Ensembl NCBI GeneCards UniProt Show fit	cystatin C
chr1_+_25272502 Show fit	1.01	ENST00000328664.9	RHD Links Ensembl NCBI GeneCards UniProt Show fit	Rh blood group D antigen
chr10_-_71851313 Show fit	0.99	ENST00000394934.4 ENST00000610929.3	PSAP Links Ensembl NCBI GeneCards UniProt Show fit	prosaposin
chr1_+_25272479 Show fit	0.97	ENST00000622561.4	RHD Links Ensembl NCBI GeneCards UniProt Show fit	Rh blood group D antigen
chr20_+_58651228 Show fit	0.93	ENST00000361830.7 ENST00000458280.5 ENST00000355957.9 ENST00000312283.12 ENST00000412911.5 ENST00000359617.8 ENST00000371141.8	STX16 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 16
chr1_+_13584262 Show fit	0.92	ENST00000376061.8 ENST00000513143.5	PDPN Links Ensembl NCBI GeneCards UniProt Show fit	podoplanin
chr22_-_39319595 Show fit	0.92	ENST00000427905.5 ENST00000216146.9 ENST00000402527.5	RPL3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L3
chr6_-_132714045 Show fit	0.91	ENST00000367928.5	VNN1 Links Ensembl NCBI GeneCards UniProt Show fit	vanin 1
chr18_-_36828771 Show fit	0.89	ENST00000589049.5 ENST00000587129.5 ENST00000590842.5	TPGS2 Links Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr5_+_141969074 Show fit	0.82	ENST00000506938.5 ENST00000394520.7 ENST00000394514.6 ENST00000512565.5	RNF14 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 14
chr17_-_80220325 Show fit	0.80	ENST00000326317.11 ENST00000570427.1 ENST00000570923.1	SGSH Links Ensembl NCBI GeneCards UniProt Show fit	N-sulfoglucosamine sulfohydrolase
chr1_-_201469151 Show fit	0.79	ENST00000367311.5 ENST00000367309.1	PHLDA3 Links Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology like domain family A member 3
chr22_-_20320009 Show fit	0.79	ENST00000405465.3 ENST00000248879.8	DGCR6L Links Ensembl NCBI GeneCards UniProt Show fit	DiGeorge syndrome critical region gene 6 like
chr1_+_25272527 Show fit	0.76	ENST00000342055.9 ENST00000357542.8 ENST00000417538.6 ENST00000423810.6 ENST00000568195.5	RHD Links Ensembl NCBI GeneCards UniProt Show fit	Rh blood group D antigen

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.1	18.3	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
4.7	18.9	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
3.8	15.2	GO:1901873	regulation of post-translational protein modification(GO:1901873)
3.8	15.0	GO:1903609	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
3.5	10.4	GO:1903422	negative regulation of synaptic vesicle recycling(GO:1903422)
3.3	10.0	GO:0008614	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
3.3	9.9	GO:1902462	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
2.7	8.1	GO:0001300	chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
2.7	8.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364) RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
2.6	23.0	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
2.4	9.6	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
2.4	14.3	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
2.4	7.1	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
2.4	16.5	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
2.3	9.3	GO:0006272	leading strand elongation(GO:0006272)
2.1	8.2	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
1.8	5.4	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.8	7.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.6	19.4	GO:0060056	mammary gland involution(GO:0060056)
1.6	9.5	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.6	4.7	GO:0035928	rRNA import into mitochondrion(GO:0035928)
1.5	4.6	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
1.5	17.9	GO:0042373	vitamin K metabolic process(GO:0042373)
1.5	4.4	GO:0090285	negative regulation of protein glycosylation in Golgi(GO:0090285)
1.5	18.9	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
1.4	21.5	GO:0070986	left/right axis specification(GO:0070986)
1.4	10.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
1.4	9.7	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
1.2	12.4	GO:0002934	desmosome organization(GO:0002934)
1.2	11.7	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.1	12.6	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
1.0	3.1	GO:0060957	endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.9	2.7	GO:0046521	sphingoid catabolic process(GO:0046521)
0.8	11.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.7	3.7	GO:1904398	positive regulation of neuromuscular junction development(GO:1904398)
0.7	10.3	GO:0022417	protein maturation by protein folding(GO:0022417)
0.7	18.9	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.7	11.0	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.7	5.4	GO:0010138	pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
0.7	5.4	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.7	2.6	GO:0021759	globus pallidus development(GO:0021759)
0.6	9.6	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.6	6.9	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.6	8.4	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.6	6.3	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.6	25.7	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.6	6.8	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.5	1.6	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.5	2.6	GO:2000814	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.5	8.0	GO:0090161	Golgi ribbon formation(GO:0090161)
0.5	2.3	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of regulatory T cell differentiation(GO:0045590)
0.4	7.0	GO:0043248	proteasome assembly(GO:0043248)
0.4	12.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.4	9.7	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.4	13.3	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.4	4.5	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.4	1.5	GO:0051541	elastin metabolic process(GO:0051541)
0.3	12.3	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.3	2.2	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.3	1.7	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.3	2.5	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.3	5.4	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.3	1.6	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3	1.3	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.2	3.7	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.2	1.5	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2	1.9	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.2	1.4	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2	1.9	GO:0071492	cellular response to UV-A(GO:0071492)
0.2	0.8	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2	2.0	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.2	0.6	GO:0034769	basement membrane disassembly(GO:0034769)
0.2	2.3	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.2	2.2	GO:0006089	lactate metabolic process(GO:0006089)
0.2	4.4	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2	3.5	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.2	4.8	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.2	9.8	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.1	1.6	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1	1.3	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	4.4	GO:0042572	retinol metabolic process(GO:0042572)
0.1	1.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	1.2	GO:2001223	negative regulation of neuron migration(GO:2001223)
0.1	3.2	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.7	GO:0061143	alveolar primary septum development(GO:0061143)
0.1	1.9	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.1	2.4	GO:0018345	protein palmitoylation(GO:0018345)
0.1	2.0	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.1	7.8	GO:0050819	negative regulation of coagulation(GO:0050819)
0.1	1.0	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.1	0.5	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.1	1.0	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.1	7.4	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.1	0.9	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.7	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	22.0	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1	0.5	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	3.0	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	4.5	GO:0031648	protein destabilization(GO:0031648)
0.1	0.6	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.1	18.9	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.1	7.1	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1	0.4	GO:0033058	directional locomotion(GO:0033058)
0.1	3.1	GO:0032456	endocytic recycling(GO:0032456)
0.1	4.6	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1	1.7	GO:0071174	mitotic spindle checkpoint(GO:0071174)
0.1	3.4	GO:0021795	cerebral cortex cell migration(GO:0021795)
0.1	0.9	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1	3.6	GO:1902400	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.2	GO:0036114	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0	13.0	GO:0006364	rRNA processing(GO:0006364)
0.0	1.3	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.3	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:1904328	lymphatic endothelial cell fate commitment(GO:0060838) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.0	0.6	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	2.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	6.5	GO:0042113	B cell activation(GO:0042113)
0.0	2.6	GO:0050729	positive regulation of inflammatory response(GO:0050729)
0.0	1.4	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.3	GO:0046548	retinal rod cell development(GO:0046548)
0.0	3.4	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	10.9	GO:0016567	protein ubiquitination(GO:0016567)
0.0	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.6	25.7	GO:0036284	tubulobulbar complex(GO:0036284)
6.5	32.4	GO:0070557	PCNA-p21 complex(GO:0070557)
3.8	18.9	GO:0042643	actomyosin, actin portion(GO:0042643)
2.8	17.1	GO:1990357	terminal web(GO:1990357)
2.1	10.7	GO:1990425	ryanodine receptor complex(GO:1990425)
1.9	13.3	GO:0005683	U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
1.8	18.3	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.8	5.4	GO:0071001	U4/U6 snRNP(GO:0071001)
1.7	12.0	GO:0005610	laminin-5 complex(GO:0005610)
1.3	14.3	GO:0005638	lamin filament(GO:0005638)
1.2	11.0	GO:0032133	chromosome passenger complex(GO:0032133)
1.2	10.4	GO:0044294	dendritic growth cone(GO:0044294)
1.1	9.5	GO:0042382	paraspeckles(GO:0042382)
1.0	7.1	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
1.0	15.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
1.0	9.7	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
1.0	4.8	GO:1902560	GMP reductase complex(GO:1902560)
0.9	21.5	GO:0030992	intraciliary transport particle B(GO:0030992)
0.9	8.4	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.9	15.0	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.9	4.4	GO:0005797	Golgi medial cisterna(GO:0005797)
0.9	13.9	GO:0097470	ribbon synapse(GO:0097470)
0.9	5.2	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.9	18.9	GO:0036020	endolysosome membrane(GO:0036020)
0.8	3.1	GO:0048179	activin receptor complex(GO:0048179)
0.7	2.2	GO:0070195	growth hormone receptor complex(GO:0070195)
0.6	7.0	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.6	3.0	GO:0000835	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.6	4.5	GO:0061700	GATOR2 complex(GO:0061700)
0.5	3.7	GO:0031415	NatA complex(GO:0031415)
0.5	15.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.5	6.8	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.4	6.9	GO:0035631	CD40 receptor complex(GO:0035631)
0.4	2.3	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.4	11.6	GO:0030057	desmosome(GO:0030057)
0.3	1.6	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2	16.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	14.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	1.2	GO:0097451	glial limiting end-foot(GO:0097451)
0.2	7.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	1.4	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	1.7	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	2.5	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	8.9	GO:0000502	proteasome complex(GO:0000502)
0.1	12.8	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.1	28.7	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1	1.5	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	3.9	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	7.1	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.1	3.7	GO:0005605	basal lamina(GO:0005605)
0.1	14.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1	1.7	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	10.3	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	2.5	GO:0031143	pseudopodium(GO:0031143)
0.1	1.3	GO:0016600	flotillin complex(GO:0016600)
0.1	1.6	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	3.0	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	3.2	GO:0031904	endosome lumen(GO:0031904)
0.1	9.4	GO:0031902	late endosome membrane(GO:0031902)
0.1	5.4	GO:0005776	autophagosome(GO:0005776)
0.1	0.3	GO:0035841	new growing cell tip(GO:0035841)
0.1	7.1	GO:0005643	nuclear pore(GO:0005643)
0.1	2.6	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	1.3	GO:0071437	invadopodium(GO:0071437)
0.1	4.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	3.9	GO:0072686	mitotic spindle(GO:0072686)
0.0	1.9	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	14.9	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	3.5	GO:0030175	filopodium(GO:0030175)
0.0	21.4	GO:0005925	focal adhesion(GO:0005925)
0.0	2.0	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0030314	junctional membrane complex(GO:0030314)
0.0	1.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	1.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.7	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	10.1	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	7.5	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.8	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.3	GO:0043194	axon initial segment(GO:0043194)
0.0	13.5	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	5.3	GO:0031012	extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.1	18.3	GO:0098808	mRNA cap binding(GO:0098808)
4.6	23.0	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
3.8	15.0	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
3.2	19.4	GO:0043120	tumor necrosis factor binding(GO:0043120)
3.1	9.3	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
3.0	17.9	GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
2.2	13.3	GO:1990446	U1 snRNP binding(GO:1990446)
2.0	13.9	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.8	16.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
1.3	5.4	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
1.3	6.3	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
1.2	9.6	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.2	10.4	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
1.0	7.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
1.0	9.7	GO:0070883	pre-miRNA binding(GO:0070883)
1.0	4.8	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.9	4.7	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.9	21.4	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.9	10.0	GO:0051525	NFAT protein binding(GO:0051525)
0.8	10.7	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.7	5.3	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.6	5.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.6	5.4	GO:0030621	U4 snRNA binding(GO:0030621)
0.6	2.2	GO:0005148	prolactin receptor binding(GO:0005148)
0.6	4.4	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.5	3.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.5	2.0	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.5	2.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.5	1.5	GO:0004998	transferrin receptor activity(GO:0004998)
0.5	19.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4	9.7	GO:0008494	translation activator activity(GO:0008494)
0.4	1.6	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.4	10.4	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4	1.6	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.4	2.7	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4	14.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.4	3.7	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.4	9.9	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.4	2.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.3	7.7	GO:0008483	transaminase activity(GO:0008483)
0.3	3.7	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3	1.6	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	7.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	9.1	GO:0005123	death receptor binding(GO:0005123)
0.2	15.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.2	0.9	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.2	42.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.2	3.5	GO:0043295	glutathione binding(GO:0043295)
0.2	2.6	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	11.0	GO:0008536	Ran GTPase binding(GO:0008536)
0.2	2.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.2	11.3	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	2.4	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	1.7	GO:0051434	BH3 domain binding(GO:0051434)
0.1	9.8	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.1	2.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	1.0	GO:0004565	beta-galactosidase activity(GO:0004565)
0.1	22.9	GO:0051015	actin filament binding(GO:0051015)
0.1	3.0	GO:0004622	lysophospholipase activity(GO:0004622)
0.1	1.9	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	3.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	2.6	GO:0004707	MAP kinase activity(GO:0004707)
0.1	3.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.3	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	0.9	GO:0008097	5S rRNA binding(GO:0008097)
0.1	1.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.1	8.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	2.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	6.7	GO:0070851	growth factor receptor binding(GO:0070851)
0.0	12.0	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	5.5	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	3.0	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.8	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	4.5	GO:0051087	chaperone binding(GO:0051087)
0.0	0.4	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	7.4	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	2.0	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	1.6	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	3.0	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.6	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	3.1	GO:0005518	collagen binding(GO:0005518)
0.0	0.4	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	2.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	1.5	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	1.3	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.4	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	6.8	GO:0045296	cadherin binding(GO:0045296)
0.0	0.7	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	1.6	GO:0019838	growth factor binding(GO:0019838)
0.0	9.0	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	1.7	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.3	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	23.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.7	18.9	PID ARF 3PATHWAY	Arf1 pathway
0.7	13.7	PID ALK2 PATHWAY	ALK2 signaling events
0.6	12.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.6	9.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.5	18.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5	10.8	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5	15.0	PID ALK1 PATHWAY	ALK1 signaling events
0.5	14.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	25.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.3	26.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.3	17.9	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.2	19.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.2	2.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.2	18.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	11.0	PID AURORA B PATHWAY	Aurora B signaling
0.2	9.3	PID BARD1 PATHWAY	BARD1 signaling events
0.2	3.7	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.2	12.6	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.2	4.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.2	8.6	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	10.0	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	2.7	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	7.1	PID P53 REGULATION PATHWAY	p53 pathway
0.1	12.1	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	17.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	6.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.3	PID IFNG PATHWAY	IFN-gamma pathway
0.1	11.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	2.7	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	3.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	2.4	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	1.3	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	3.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	3.6	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	17.9	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.9	13.3	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.8	16.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.7	24.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.7	16.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.6	9.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.6	11.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.5	10.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5	14.7	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.4	13.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.4	12.0	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.4	8.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.4	5.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.3	9.7	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.3	22.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	15.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	30.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.2	3.8	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.2	4.8	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	13.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	5.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.2	4.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	18.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.2	4.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	3.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	7.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	2.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	13.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	2.3	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.1	1.6	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	12.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	2.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	1.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	0.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.9	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	6.3	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	3.6	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	1.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.8	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.4	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions