ISMARA results: TP63

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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TP63

Z-value: 1.46

Motif logo

Transcription factors associated with TP63

Gene Symbol	Gene ID	Gene Info
TP63 Ensembl NCBI GeneCards UniProt	ENSG00000073282.14	TP63

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TP63	hg38_v1_chr3_+_189789734_189789801	-0.55	2.4e-18	Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr12_-_122227449 Show fit	40.24	ENST00000650715.1	DIABLO Ensembl NCBI GeneCards UniProt Show fit	diablo IAP-binding mitochondrial protein
chr12_-_122227491 Show fit	39.43	ENST00000475784.1 ENST00000645606.1	ENSG00000284934.2 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr15_-_63156774 Show fit	34.75	ENST00000462430.5	RPS27L Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S27 like
chr2_-_150487658 Show fit	31.11	ENST00000375734.6 ENST00000263895.9 ENST00000454202.5	RND3 Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 3
chr17_+_51153551 Show fit	30.96	ENST00000393196.8 ENST00000336097.7 ENST00000480143.5 ENST00000511355.5 ENST00000393193.6 ENST00000376392.10	NME1 Ensembl NCBI GeneCards UniProt Show fit NME1-NME2 Ensembl NCBI GeneCards UniProt Show fit	NME/NM23 nucleoside diphosphate kinase 1 NME1-NME2 readthrough
chr1_+_236395394 Show fit	30.52	ENST00000359362.6	EDARADD Ensembl NCBI GeneCards UniProt Show fit	EDAR associated death domain
chr16_+_51553436 Show fit	30.02	ENST00000565308.2	HNRNPA1P48 Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein A1 pseudogene 48
chr17_+_51153628 Show fit	29.11	ENST00000555572.1 ENST00000013034.3	NME1-NME2 Ensembl NCBI GeneCards UniProt Show fit NME1 Ensembl NCBI GeneCards UniProt Show fit	NME1-NME2 readthrough NME/NM23 nucleoside diphosphate kinase 1
chr19_+_48993864 Show fit	28.72	ENST00000595090.6	RUVBL2 Ensembl NCBI GeneCards UniProt Show fit	RuvB like AAA ATPase 2
chr2_+_74206384 Show fit	27.89	ENST00000678623.1 ENST00000678731.1	MTHFD2 Ensembl NCBI GeneCards UniProt Show fit	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr5_+_163437569 Show fit	26.34	ENST00000512163.5 ENST00000393929.5 ENST00000510097.5 ENST00000340828.7 ENST00000511490.4 ENST00000510664.5	CCNG1 Ensembl NCBI GeneCards UniProt Show fit	cyclin G1
chr3_+_184362599 Show fit	26.17	ENST00000455712.5	POLR2H Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II, I and III subunit H
chr6_+_10747753 Show fit	24.34	ENST00000612333.4	TMEM14B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 14B
chr6_+_10747765 Show fit	23.54	ENST00000461342.5 ENST00000475942.5 ENST00000379542.10 ENST00000379530.7 ENST00000473276.5 ENST00000481240.5 ENST00000467317.5	TMEM14B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 14B
chr10_+_123154768 Show fit	21.79	ENST00000407911.2	BUB3 Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chrX_-_154374623 Show fit	21.59	ENST00000369850.10	FLNA Ensembl NCBI GeneCards UniProt Show fit	filamin A
chr15_-_63157464 Show fit	21.36	ENST00000330964.10 ENST00000635699.1 ENST00000439025.1	RPS27L Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S27 like
chr17_+_75234704 Show fit	21.24	ENST00000579838.1	NUP85 Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 85
chr20_+_36605734 Show fit	21.23	ENST00000344795.8 ENST00000373852.9	RAB5IF Ensembl NCBI GeneCards UniProt Show fit	RAB5 interacting factor
chr1_+_37692463 Show fit	21.13	ENST00000327331.2	CDCA8 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle associated 8
chr18_+_59899988 Show fit	20.73	ENST00000316660.7 ENST00000269518.9	PMAIP1 Ensembl NCBI GeneCards UniProt Show fit	phorbol-12-myristate-13-acetate-induced protein 1
chr15_-_72231583 Show fit	20.64	ENST00000566809.1 ENST00000567087.5 ENST00000569050.1 ENST00000568883.5	PKM Ensembl NCBI GeneCards UniProt Show fit	pyruvate kinase M1/2
chr14_+_51989609 Show fit	20.45	ENST00000556760.5	RTRAF Ensembl NCBI GeneCards UniProt Show fit	RNA transcription, translation and transport factor
chr20_+_36605820 Show fit	20.25	ENST00000342422.3	RAB5IF Ensembl NCBI GeneCards UniProt Show fit	RAB5 interacting factor
chr1_+_37692506 Show fit	20.23	ENST00000373055.6	CDCA8 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle associated 8
chr2_+_197500398 Show fit	20.10	ENST00000604458.1	HSPE1-MOB4 Ensembl NCBI GeneCards UniProt Show fit	HSPE1-MOB4 readthrough
chr2_-_46941710 Show fit	19.16	ENST00000409207.5	MCFD2 Ensembl NCBI GeneCards UniProt Show fit	multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr5_+_171387757 Show fit	19.04	ENST00000677297.1 ENST00000521672.6 ENST00000679190.1 ENST00000351986.10 ENST00000676589.1 ENST00000679233.1 ENST00000677357.1 ENST00000296930.10 ENST00000393820.2 ENST00000523622.1	NPM1 Ensembl NCBI GeneCards UniProt Show fit	nucleophosmin 1
chr22_+_38982341 Show fit	18.60	ENST00000407298.7 ENST00000333467.4	APOBEC3B Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 3B
chr3_+_184363427 Show fit	18.53	ENST00000429568.1	POLR2H Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II, I and III subunit H
chr3_+_184363387 Show fit	18.20	ENST00000452961.5	POLR2H Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II, I and III subunit H
chr5_+_116084992 Show fit	18.06	ENST00000274458.9 ENST00000632434.1	COMMD10 Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 10
chr19_+_41219177 Show fit	17.94	ENST00000301178.9	AXL Ensembl NCBI GeneCards UniProt Show fit	AXL receptor tyrosine kinase
chr19_+_18386150 Show fit	17.75	ENST00000252809.3	GDF15 Ensembl NCBI GeneCards UniProt Show fit	growth differentiation factor 15
chr2_+_197500371 Show fit	17.72	ENST00000409468.1 ENST00000233893.10	HSPE1 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family E (Hsp10) member 1
chrX_+_150980504 Show fit	17.55	ENST00000419110.5	HMGB3 Ensembl NCBI GeneCards UniProt Show fit	high mobility group box 3
chr22_+_38982370 Show fit	17.51	ENST00000402182.7	APOBEC3B Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 3B
chr11_-_14520323 Show fit	16.99	ENST00000530457.5 ENST00000532256.1 ENST00000396394.7	PSMA1 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 1
chr3_+_184363351 Show fit	16.82	ENST00000443489.5	POLR2H Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II, I and III subunit H
chr2_+_177392734 Show fit	16.69	ENST00000680770.1 ENST00000637633.2 ENST00000679459.1 ENST00000409888.1 ENST00000264167.11 ENST00000642466.2	AGPS Ensembl NCBI GeneCards UniProt Show fit	alkylglycerone phosphate synthase
chr3_+_44976236 Show fit	16.54	ENST00000265564.8	EXOSC7 Ensembl NCBI GeneCards UniProt Show fit	exosome component 7
chr6_+_36676455 Show fit	16.39	ENST00000615513.4	CDKN1A Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 1A
chr22_-_36528897 Show fit	16.37	ENST00000405442.5 ENST00000402116.2	EIF3D Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit D
chr6_+_36676489 Show fit	16.30	ENST00000448526.6	CDKN1A Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 1A
chr7_+_44797114 Show fit	16.27	ENST00000677022.1	PPIA Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase A
chr1_-_209651291 Show fit	16.23	ENST00000391911.5 ENST00000415782.1	LAMB3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 3
chr14_+_51989508 Show fit	16.11	ENST00000261700.8	RTRAF Ensembl NCBI GeneCards UniProt Show fit	RNA transcription, translation and transport factor
chr21_-_25607474 Show fit	16.09	ENST00000352957.9 ENST00000419219.1 ENST00000307301.11	MRPL39 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L39
chr11_-_78139258 Show fit	15.81	ENST00000530910.6 ENST00000681417.1 ENST00000681225.1 ENST00000681765.1 ENST00000525870.6 ENST00000530608.6 ENST00000532306.6 ENST00000376156.7 ENST00000681699.1 ENST00000681221.1 ENST00000679444.1 ENST00000680829.1 ENST00000680761.1 ENST00000680256.1 ENST00000525783.6 ENST00000529139.6 ENST00000680580.1 ENST00000526849.6 ENST00000680399.1 ENST00000527099.2 ENST00000681489.1 ENST00000299626.10 ENST00000679497.1 ENST00000680101.1 ENST00000532440.6 ENST00000530454.6 ENST00000525761.3 ENST00000681575.1 ENST00000679559.1 ENST00000680398.1 ENST00000615266.5 ENST00000680643.1	ALG8 Ensembl NCBI GeneCards UniProt Show fit	ALG8 alpha-1,3-glucosyltransferase
chr15_-_66524518 Show fit	15.75	ENST00000568588.5	RPL4 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L4
chr19_+_48321454 Show fit	15.58	ENST00000599704.5	EMP3 Ensembl NCBI GeneCards UniProt Show fit	epithelial membrane protein 3
chr17_+_8288637 Show fit	15.57	ENST00000407006.8 ENST00000226105.11 ENST00000580434.5 ENST00000439238.3	RANGRF Ensembl NCBI GeneCards UniProt Show fit	RAN guanine nucleotide release factor
chr22_-_36529136 Show fit	14.89	ENST00000216190.13 ENST00000455547.5	EIF3D Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit D
chr5_-_179624578 Show fit	14.67	ENST00000505811.5 ENST00000515714.5 ENST00000513225.5 ENST00000503664.1 ENST00000356731.9 ENST00000523137.5	HNRNPH1 Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein H1
chr21_-_17612842 Show fit	14.48	ENST00000339775.10 ENST00000348354.7	BTG3 Ensembl NCBI GeneCards UniProt Show fit	BTG anti-proliferation factor 3
chr10_+_123154414 Show fit	14.08	ENST00000368858.9	BUB3 Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr6_+_31666802 Show fit	13.87	ENST00000617558.2	ENSG00000263020.6 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr6_-_100881281 Show fit	13.50	ENST00000369143.2 ENST00000369162.7 ENST00000324723.10 ENST00000522650.5	ASCC3 Ensembl NCBI GeneCards UniProt Show fit	activating signal cointegrator 1 complex subunit 3
chr8_+_81280527 Show fit	13.17	ENST00000297258.11	FABP5 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 5
chr1_-_32817311 Show fit	13.04	ENST00000373477.9 ENST00000675785.1	YARS1 Ensembl NCBI GeneCards UniProt Show fit	tyrosyl-tRNA synthetase 1
chr8_-_48921419 Show fit	12.97	ENST00000020945.4	SNAI2 Ensembl NCBI GeneCards UniProt Show fit	snail family transcriptional repressor 2
chr12_+_6494087 Show fit	12.25	ENST00000382457.8 ENST00000315579.10	NCAPD2 Ensembl NCBI GeneCards UniProt Show fit	non-SMC condensin I complex subunit D2
chr2_-_33599269 Show fit	12.11	ENST00000431950.1 ENST00000403368.1 ENST00000238823.13	FAM98A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 98 member A
chr2_-_46941760 Show fit	11.88	ENST00000444761.6 ENST00000409147.1	MCFD2 Ensembl NCBI GeneCards UniProt Show fit	multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr8_+_22580451 Show fit	11.66	ENST00000622702.1 ENST00000409141.5 ENST00000265810.8	PDLIM2 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 2
chr8_-_73294425 Show fit	11.49	ENST00000396465.5	RPL7 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L7
chr19_+_535824 Show fit	11.16	ENST00000606065.3	CDC34 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 34, ubiqiutin conjugating enzyme
chr19_-_18940289 Show fit	10.79	ENST00000542541.6 ENST00000433218.6	HOMER3 Ensembl NCBI GeneCards UniProt Show fit	homer scaffold protein 3
chr10_+_100347225 Show fit	10.63	ENST00000370355.3	SCD Ensembl NCBI GeneCards UniProt Show fit	stearoyl-CoA desaturase
chr8_-_116766255 Show fit	10.62	ENST00000276682.8	EIF3H Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit H
chr2_-_177392673 Show fit	10.61	ENST00000447413.1 ENST00000397057.6 ENST00000456746.5 ENST00000464747.5	ENSG00000213963.6 Ensembl NCBI GeneCards UniProt Show fit NFE2L2 Ensembl NCBI GeneCards UniProt Show fit	novel transcript nuclear factor, erythroid 2 like 2
chr2_+_216659600 Show fit	10.35	ENST00000456764.1	IGFBP2 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 2
chr13_+_48037692 Show fit	10.27	ENST00000258662.3	NUDT15 Ensembl NCBI GeneCards UniProt Show fit	nudix hydrolase 15
chr3_+_44799187 Show fit	10.12	ENST00000425755.5	KIF15 Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 15
chr8_+_30095649 Show fit	10.05	ENST00000518192.5	LEPROTL1 Ensembl NCBI GeneCards UniProt Show fit	leptin receptor overlapping transcript like 1
chr1_+_44775531 Show fit	9.94	ENST00000396651.8 ENST00000372209.3	RPS8 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S8
chr19_-_46784905 Show fit	9.81	ENST00000594991.5	SLC1A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 5
chr7_+_140696696 Show fit	9.73	ENST00000247866.9 ENST00000464566.5	NDUFB2 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B2
chr2_-_130509287 Show fit	9.65	ENST00000615053.3 ENST00000631234.1 ENST00000451531.7	POTEI Ensembl NCBI GeneCards UniProt Show fit	POTE ankyrin domain family member I
chr1_-_153615858 Show fit	9.54	ENST00000476873.5	S100A14 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A14
chr10_+_123154364 Show fit	9.53	ENST00000368859.6 ENST00000368865.9	BUB3 Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr10_+_87863595 Show fit	9.53	ENST00000371953.8	PTEN Ensembl NCBI GeneCards UniProt Show fit	phosphatase and tensin homolog
chrX_-_132218124 Show fit	9.35	ENST00000342983.6	RAP2C Ensembl NCBI GeneCards UniProt Show fit	RAP2C, member of RAS oncogene family
chr4_+_70688511 Show fit	9.32	ENST00000254803.4	UTP3 Ensembl NCBI GeneCards UniProt Show fit	UTP3 small subunit processome component
chr1_+_159009886 Show fit	9.31	ENST00000340979.10 ENST00000368131.8 ENST00000295809.12 ENST00000368132.7	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr7_+_140696665 Show fit	9.23	ENST00000476279.5 ENST00000461457.1 ENST00000465506.5	NDUFB2 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B2
chr4_+_69096494 Show fit	9.12	ENST00000508661.5 ENST00000622664.1	UGT2B7 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B7
chr20_-_6123019 Show fit	9.11	ENST00000217289.9 ENST00000536936.1	FERMT1 Ensembl NCBI GeneCards UniProt Show fit	fermitin family member 1
chr1_+_155689074 Show fit	9.04	ENST00000343043.7 ENST00000421487.6 ENST00000535183.5 ENST00000368336.10 ENST00000465375.5 ENST00000470830.5	DAP3 Ensembl NCBI GeneCards UniProt Show fit	death associated protein 3
chr4_-_24584517 Show fit	9.00	ENST00000336812.5	DHX15 Ensembl NCBI GeneCards UniProt Show fit	DEAH-box helicase 15
chr4_-_10116779 Show fit	8.87	ENST00000499869.7	WDR1 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 1
chr19_-_46784733 Show fit	8.79	ENST00000593713.1 ENST00000598022.1 ENST00000434726.6	SLC1A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 5
chr1_+_159010002 Show fit	8.57	ENST00000359709.7	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr7_+_80133830 Show fit	8.45	ENST00000648098.1 ENST00000648476.1 ENST00000648412.1 ENST00000648953.1 ENST00000648306.1 ENST00000648832.1 ENST00000648877.1 ENST00000442586.2 ENST00000649487.1 ENST00000649267.1	GNAI1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha i1
chr4_-_105708639 Show fit	8.42	ENST00000416543.5 ENST00000515819.1 ENST00000420368.6 ENST00000503746.5 ENST00000433009.1 ENST00000340139.10	INTS12 Ensembl NCBI GeneCards UniProt Show fit	integrator complex subunit 12
chr1_-_47190013 Show fit	8.37	ENST00000294338.7	PDZK1IP1 Ensembl NCBI GeneCards UniProt Show fit	PDZK1 interacting protein 1
chr4_+_69096467 Show fit	8.30	ENST00000305231.12	UGT2B7 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B7
chr2_+_100562941 Show fit	8.17	ENST00000264254.11	PDCL3 Ensembl NCBI GeneCards UniProt Show fit	phosducin like 3
chr14_+_18967434 Show fit	8.15	ENST00000547889.6	POTEM Ensembl NCBI GeneCards UniProt Show fit	POTE ankyrin domain family member M
chr21_-_33915762 Show fit	8.14	ENST00000290299.7	ATP5PO Ensembl NCBI GeneCards UniProt Show fit	ATP synthase peripheral stalk subunit OSCP
chr1_-_88992924 Show fit	8.11	ENST00000370486.1 ENST00000399794.6	KYAT3 Ensembl NCBI GeneCards UniProt Show fit RBMXL1 Ensembl NCBI GeneCards UniProt Show fit	kynurenine aminotransferase 3 RBMX like 1
chr22_+_39014282 Show fit	8.10	ENST00000381568.9	ENSG00000284554.2 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr6_+_31666056 Show fit	7.98	ENST00000375882.7 ENST00000375880.6	CSNK2B Ensembl NCBI GeneCards UniProt Show fit ENSG00000263020.6 Ensembl NCBI GeneCards UniProt Show fit	casein kinase 2 beta novel protein
chr3_+_69866217 Show fit	7.97	ENST00000314589.10	MITF Ensembl NCBI GeneCards UniProt Show fit	melanocyte inducing transcription factor
chrX_-_130110479 Show fit	7.89	ENST00000308167.10	ELF4 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 4
chr9_+_131190119 Show fit	7.71	ENST00000483497.6	NUP214 Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 214
chr6_-_111483700 Show fit	7.38	ENST00000435970.5 ENST00000358835.7	REV3L Ensembl NCBI GeneCards UniProt Show fit	REV3 like, DNA directed polymerase zeta catalytic subunit
chr19_-_6591103 Show fit	7.37	ENST00000423145.7 ENST00000245903.4	CD70 Ensembl NCBI GeneCards UniProt Show fit	CD70 molecule
chr13_+_75760431 Show fit	7.36	ENST00000321797.12	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr1_-_12616762 Show fit	7.28	ENST00000464917.5	DHRS3 Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase 3
chr3_-_127591036 Show fit	7.26	ENST00000489960.5 ENST00000490290.5	TPRA1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein adipocyte associated 1
chr1_+_32179665 Show fit	7.16	ENST00000373610.8	TXLNA Ensembl NCBI GeneCards UniProt Show fit	taxilin alpha
chr3_+_14178808 Show fit	7.10	ENST00000306024.4	LSM3 Ensembl NCBI GeneCards UniProt Show fit	LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr20_-_44651683 Show fit	7.08	ENST00000537820.1 ENST00000372874.9	ADA Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase
chr7_+_140697144 Show fit	7.07	ENST00000476470.5 ENST00000471136.5	NDUFB2 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B2
chr9_-_86100123 Show fit	7.03	ENST00000388711.7 ENST00000466178.1	GOLM1 Ensembl NCBI GeneCards UniProt Show fit	golgi membrane protein 1
chr17_+_19648792 Show fit	7.02	ENST00000630662.2	ALDH3A2 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 3 family member A2
chr10_+_5684828 Show fit	6.92	ENST00000328090.9 ENST00000496681.5	TASOR2 Ensembl NCBI GeneCards UniProt Show fit	transcription activation suppressor family member 2
chrX_+_48476021 Show fit	6.84	ENST00000396894.8 ENST00000019019.6 ENST00000348411.3	FTSJ1 Ensembl NCBI GeneCards UniProt Show fit	FtsJ RNA 2'-O-methyltransferase 1
chr20_+_36091409 Show fit	6.69	ENST00000202028.9	EPB41L1 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 1
chr8_-_23069012 Show fit	6.58	ENST00000347739.3 ENST00000276431.9	TNFRSF10B Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 10b
chr9_-_127937800 Show fit	6.57	ENST00000373110.4 ENST00000314392.13	DPM2 Ensembl NCBI GeneCards UniProt Show fit	dolichyl-phosphate mannosyltransferase subunit 2, regulatory
chr7_+_5045821 Show fit	6.51	ENST00000353796.7 ENST00000396912.2 ENST00000396904.2	RBAK Ensembl NCBI GeneCards UniProt Show fit RBAK-RBAKDN Ensembl NCBI GeneCards UniProt Show fit	RB associated KRAB zinc finger RBAK-RBAKDN readthrough
chr20_+_36306325 Show fit	6.31	ENST00000373913.7 ENST00000339266.10	DLGAP4 Ensembl NCBI GeneCards UniProt Show fit	DLG associated protein 4
chrX_+_154379336 Show fit	6.24	ENST00000682114.1	EMD Ensembl NCBI GeneCards UniProt Show fit	emerin
chrX_-_130110679 Show fit	6.07	ENST00000335997.11	ELF4 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 4
chr2_+_130611440 Show fit	6.00	ENST00000409602.2	POTEJ Ensembl NCBI GeneCards UniProt Show fit	POTE ankyrin domain family member J
chr16_+_57620077 Show fit	5.94	ENST00000567835.5 ENST00000569372.5 ENST00000563548.5 ENST00000562003.5	ADGRG1 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor G1
chr1_+_116373233 Show fit	5.90	ENST00000295598.10	ATP1A1 Ensembl NCBI GeneCards UniProt Show fit	ATPase Na+/K+ transporting subunit alpha 1
chr1_+_32180044 Show fit	5.90	ENST00000373609.1	TXLNA Ensembl NCBI GeneCards UniProt Show fit	taxilin alpha
chr16_+_57619942 Show fit	5.82	ENST00000568908.5 ENST00000568909.5 ENST00000566778.5 ENST00000561988.5	ADGRG1 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor G1
chr7_+_140696956 Show fit	5.79	ENST00000460088.5 ENST00000472695.5	NDUFB2 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B2
chr12_-_124863783 Show fit	5.69	ENST00000546215.5 ENST00000415380.6 ENST00000545493.1 ENST00000261693.11 ENST00000680596.1	SCARB1 Ensembl NCBI GeneCards UniProt Show fit	scavenger receptor class B member 1
chr2_+_11612253 Show fit	5.61	ENST00000396123.2	GREB1 Ensembl NCBI GeneCards UniProt Show fit	growth regulating estrogen receptor binding 1
chr11_+_63974578 Show fit	5.53	ENST00000314133.4 ENST00000535431.1	COX8A Ensembl NCBI GeneCards UniProt Show fit ENSG00000256100.1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 8A novel transcript
chr17_-_42577663 Show fit	5.49	ENST00000590760.5 ENST00000587209.5 ENST00000393795.8 ENST00000253789.9	PSMC3IP Ensembl NCBI GeneCards UniProt Show fit	PSMC3 interacting protein
chrX_+_154379433 Show fit	5.44	ENST00000683627.1	EMD Ensembl NCBI GeneCards UniProt Show fit	emerin
chrX_-_9765839 Show fit	5.29	ENST00000467482.6	GPR143 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 143
chr15_+_51829644 Show fit	5.26	ENST00000308580.12	TMOD3 Ensembl NCBI GeneCards UniProt Show fit	tropomodulin 3
chr17_-_28335421 Show fit	5.25	ENST00000578122.5 ENST00000579419.5 ENST00000585313.5 ENST00000578985.5 ENST00000577498.1 ENST00000585089.5 ENST00000357896.7 ENST00000395418.8 ENST00000588477.5	IFT20 Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 20
chr3_-_49358340 Show fit	5.24	ENST00000419783.3	GPX1 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 1
chr20_+_32762378 Show fit	5.22	ENST00000328111.6 ENST00000348286.6 ENST00000353855.6	DNMT3B Ensembl NCBI GeneCards UniProt Show fit	DNA methyltransferase 3 beta
chr17_-_13017952 Show fit	5.12	ENST00000578071.1 ENST00000426905.7 ENST00000395962.6 ENST00000338034.9 ENST00000583371.5	ELAC2 Ensembl NCBI GeneCards UniProt Show fit	elaC ribonuclease Z 2
chr1_-_93847150 Show fit	5.12	ENST00000370244.5	BCAR3 Ensembl NCBI GeneCards UniProt Show fit	BCAR3 adaptor protein, NSP family member
chr22_+_37805218 Show fit	5.01	ENST00000340857.4	H1-0 Ensembl NCBI GeneCards UniProt Show fit	H1.0 linker histone
chr2_+_68157877 Show fit	4.96	ENST00000263657.7	PNO1 Ensembl NCBI GeneCards UniProt Show fit	partner of NOB1 homolog
chr3_-_49358272 Show fit	4.86	ENST00000419349.2	GPX1 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 1
chr4_-_143905529 Show fit	4.85	ENST00000358615.9 ENST00000437468.2	GYPE Ensembl NCBI GeneCards UniProt Show fit	glycophorin E (MNS blood group)
chr19_+_41860236 Show fit	4.85	ENST00000601492.5 ENST00000600467.6 ENST00000598742.6 ENST00000221975.6 ENST00000598261.2	RPS19 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S19
chr3_-_49358320 Show fit	4.80	ENST00000643797.1 ENST00000646881.2 ENST00000496791.2	GPX1 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 1
chr12_-_124863902 Show fit	4.77	ENST00000339570.9 ENST00000680556.1	SCARB1 Ensembl NCBI GeneCards UniProt Show fit	scavenger receptor class B member 1
chr2_+_168456215 Show fit	4.70	ENST00000392687.4 ENST00000305747.11	CERS6 Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 6
chr12_-_52452139 Show fit	4.63	ENST00000252252.4	KRT6B Ensembl NCBI GeneCards UniProt Show fit	keratin 6B
chr12_+_55973913 Show fit	4.58	ENST00000553116.5	RAB5B Ensembl NCBI GeneCards UniProt Show fit	RAB5B, member RAS oncogene family
chr8_+_66429003 Show fit	4.51	ENST00000320270.4	RRS1 Ensembl NCBI GeneCards UniProt Show fit	ribosome biogenesis regulator 1 homolog
chr11_+_76782250 Show fit	4.50	ENST00000533752.1 ENST00000612930.1	TSKU Ensembl NCBI GeneCards UniProt Show fit	tsukushi, small leucine rich proteoglycan
chr18_+_63476927 Show fit	4.42	ENST00000489441.5 ENST00000382771.9 ENST00000424602.1	SERPINB5 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 5
chrX_+_154379203 Show fit	4.35	ENST00000369835.3 ENST00000369842.9	EMD Ensembl NCBI GeneCards UniProt Show fit	emerin
chr15_+_68277724 Show fit	4.32	ENST00000306917.5	FEM1B Ensembl NCBI GeneCards UniProt Show fit	fem-1 homolog B
chr4_-_144019287 Show fit	4.30	ENST00000638448.1 ENST00000513128.5 ENST00000506516.6 ENST00000429670.3 ENST00000502664.6	GYPB Ensembl NCBI GeneCards UniProt Show fit	glycophorin B (MNS blood group)
chr15_-_88913362 Show fit	4.29	ENST00000558029.5 ENST00000268150.13 ENST00000542878.5 ENST00000268151.11 ENST00000566497.5	MFGE8 Ensembl NCBI GeneCards UniProt Show fit	milk fat globule EGF and factor V/VIII domain containing
chr17_+_50478794 Show fit	4.26	ENST00000258955.7	RSAD1 Ensembl NCBI GeneCards UniProt Show fit	radical S-adenosyl methionine domain containing 1
chr11_+_36296281 Show fit	4.17	ENST00000530639.6	PRR5L Ensembl NCBI GeneCards UniProt Show fit	proline rich 5 like
chr15_-_31101707 Show fit	4.13	ENST00000397795.6 ENST00000256552.11 ENST00000559179.2	TRPM1 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily M member 1
chr9_+_116687295 Show fit	4.11	ENST00000450136.2 ENST00000373983.2 ENST00000411410.1	TRIM32 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 32
chr5_+_154190725 Show fit	4.03	ENST00000425427.6 ENST00000297107.11	GALNT10 Ensembl NCBI GeneCards UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 10
chr4_+_677922 Show fit	4.00	ENST00000400159.6	MYL5 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 5
chr3_-_111595339 Show fit	3.93	ENST00000317012.5	ZBED2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger BED-type containing 2
chr11_+_65122301 Show fit	3.93	ENST00000534078.1 ENST00000526171.5 ENST00000279242.7 ENST00000531705.1 ENST00000533943.1	MRPL49 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L49
chr4_+_678189 Show fit	3.89	ENST00000507804.1	MYL5 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 5
chr3_+_53168687 Show fit	3.88	ENST00000650940.1 ENST00000654719.1	PRKCD Ensembl NCBI GeneCards UniProt Show fit	protein kinase C delta
chr12_-_52493250 Show fit	3.86	ENST00000330722.7	KRT6A Ensembl NCBI GeneCards UniProt Show fit	keratin 6A
chr5_+_179820895 Show fit	3.81	ENST00000504627.1 ENST00000389805.9 ENST00000510187.5	SQSTM1 Ensembl NCBI GeneCards UniProt Show fit	sequestosome 1
chr5_+_42423433 Show fit	3.75	ENST00000230882.9	GHR Ensembl NCBI GeneCards UniProt Show fit	growth hormone receptor
chr1_-_31644866 Show fit	3.60	ENST00000373703.5	PEF1 Ensembl NCBI GeneCards UniProt Show fit	penta-EF-hand domain containing 1
chr16_-_70695593 Show fit	3.54	ENST00000567648.1	VAC14 Ensembl NCBI GeneCards UniProt Show fit	VAC14 component of PIKFYVE complex
chrX_+_9912434 Show fit	3.52	ENST00000418909.6	SHROOM2 Ensembl NCBI GeneCards UniProt Show fit	shroom family member 2
chr2_-_164842011 Show fit	3.51	ENST00000409184.8 ENST00000456693.5	COBLL1 Ensembl NCBI GeneCards UniProt Show fit	cordon-bleu WH2 repeat protein like 1
chr16_+_2496032 Show fit	3.50	ENST00000564543.1	ENSG00000260272.1 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr10_+_91798398 Show fit	3.43	ENST00000371627.5	TNKS2 Ensembl NCBI GeneCards UniProt Show fit	tankyrase 2
chr20_-_54173976 Show fit	3.36	ENST00000216862.8	CYP24A1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 24 subfamily A member 1
chr3_-_88058928 Show fit	3.25	ENST00000482016.6	CGGBP1 Ensembl NCBI GeneCards UniProt Show fit	CGG triplet repeat binding protein 1
chr3_-_88059042 Show fit	3.24	ENST00000309534.10	CGGBP1 Ensembl NCBI GeneCards UniProt Show fit	CGG triplet repeat binding protein 1
chr4_-_144140725 Show fit	3.23	ENST00000360771.8	GYPA Ensembl NCBI GeneCards UniProt Show fit	glycophorin A (MNS blood group)
chr5_-_157059109 Show fit	3.19	ENST00000523175.6 ENST00000522693.5	HAVCR1 Ensembl NCBI GeneCards UniProt Show fit	hepatitis A virus cellular receptor 1
chr17_-_43125450 Show fit	3.14	ENST00000494123.5 ENST00000468300.5 ENST00000471181.7 ENST00000652672.1	BRCA1 Ensembl NCBI GeneCards UniProt Show fit	BRCA1 DNA repair associated
chr3_-_44976117 Show fit	3.12	ENST00000342790.8 ENST00000424952.7 ENST00000339420.7 ENST00000296127.7 ENST00000455235.5	ZDHHC3 Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 3
chr4_-_144140712 Show fit	2.99	ENST00000641688.3	GYPA Ensembl NCBI GeneCards UniProt Show fit	glycophorin A (MNS blood group)
chr11_+_111937320 Show fit	2.90	ENST00000440460.7	DIXDC1 Ensembl NCBI GeneCards UniProt Show fit	DIX domain containing 1
chr9_-_136050502 Show fit	2.88	ENST00000371753.5	NACC2 Ensembl NCBI GeneCards UniProt Show fit	NACC family member 2
chr4_-_144140635 Show fit	2.80	ENST00000512064.5 ENST00000512789.5 ENST00000504786.5 ENST00000503627.2 ENST00000642713.1 ENST00000643148.1 ENST00000642738.1 ENST00000642295.1 ENST00000646447.1 ENST00000535709.6	GYPA Ensembl NCBI GeneCards UniProt Show fit	glycophorin A (MNS blood group)
chr10_+_88990736 Show fit	2.77	ENST00000357339.6 ENST00000652046.1 ENST00000355279.2	FAS Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr17_+_28335718 Show fit	2.76	ENST00000226225.7	TNFAIP1 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 1
chr14_-_91244669 Show fit	2.71	ENST00000650645.1	GPR68 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 68
chr16_+_88803776 Show fit	2.68	ENST00000301019.9	CDT1 Ensembl NCBI GeneCards UniProt Show fit	chromatin licensing and DNA replication factor 1
chr1_+_86424154 Show fit	2.66	ENST00000370565.5	CLCA2 Ensembl NCBI GeneCards UniProt Show fit	chloride channel accessory 2
chr11_+_18266254 Show fit	2.55	ENST00000532858.5 ENST00000649195.1 ENST00000356524.9 ENST00000405158.2	SAA1 Ensembl NCBI GeneCards UniProt Show fit	serum amyloid A1
chr20_+_63235899 Show fit	2.54	ENST00000217169.8	BIRC7 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 7
chrX_-_154409246 Show fit	2.50	ENST00000369807.6	DNASE1L1 Ensembl NCBI GeneCards UniProt Show fit	deoxyribonuclease 1 like 1
chr12_+_55974059 Show fit	2.50	ENST00000360299.10 ENST00000548068.5 ENST00000549915.5 ENST00000551459.5 ENST00000448789.2	RAB5B Ensembl NCBI GeneCards UniProt Show fit	RAB5B, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.4	31.3	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
7.2	21.6	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
7.2	28.7	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
5.6	16.7	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
5.5	16.5	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
5.3	5.3	GO:1902908	regulation of melanosome transport(GO:1902908)
5.2	15.6	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
5.0	14.9	GO:1902905	positive regulation of fibril organization(GO:1902905)
4.6	18.6	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
4.3	13.0	GO:1901420	negative regulation of response to alcohol(GO:1901420)
3.6	32.7	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
3.5	10.5	GO:0015920	lipopolysaccharide transport(GO:0015920)
3.1	40.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
3.0	9.1	GO:0048817	negative regulation of hair follicle maturation(GO:0048817)
3.0	60.1	GO:0006228	UTP biosynthetic process(GO:0006228)
3.0	17.9	GO:0048549	positive regulation of pinocytosis(GO:0048549)
2.8	36.7	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
2.7	10.6	GO:1901377	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
2.5	61.0	GO:0000028	ribosomal small subunit assembly(GO:0000028)
2.4	9.5	GO:1903984	rhythmic synaptic transmission(GO:0060024) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
2.4	7.1	GO:0070256	germinal center B cell differentiation(GO:0002314) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) xanthine metabolic process(GO:0046110) negative regulation of mucus secretion(GO:0070256)
2.2	8.9	GO:0042247	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
2.1	19.0	GO:0060699	regulation of endoribonuclease activity(GO:0060699)
2.0	12.3	GO:0010032	meiotic chromosome condensation(GO:0010032)
2.0	8.2	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.7	20.7	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
1.7	5.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
1.7	79.7	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
1.7	13.5	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
1.6	16.3	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.6	13.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
1.6	16.0	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
1.6	14.0	GO:0001866	NK T cell proliferation(GO:0001866)
1.5	6.0	GO:1903173	phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
1.4	10.0	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
1.4	8.1	GO:0097052	L-kynurenine metabolic process(GO:0097052)
1.3	6.6	GO:0019348	dolichol metabolic process(GO:0019348)
1.3	3.9	GO:2000755	regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
1.3	3.9	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
1.3	10.3	GO:0006203	dGTP catabolic process(GO:0006203)
1.2	48.1	GO:0071173	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
1.1	11.5	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.1	3.4	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
1.1	4.5	GO:0061073	ciliary body morphogenesis(GO:0061073)
1.1	11.2	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
1.1	4.3	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
1.0	3.1	GO:0070512	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
1.0	4.1	GO:0030047	actin modification(GO:0030047)
1.0	8.0	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.9	45.9	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.9	15.8	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.9	11.8	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.9	5.3	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.9	27.9	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.9	5.2	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.9	1.7	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.8	18.5	GO:0052695	cellular glucuronidation(GO:0052695)
0.8	3.4	GO:0042369	vitamin D catabolic process(GO:0042369)
0.8	7.3	GO:0040016	embryonic cleavage(GO:0040016)
0.8	3.8	GO:0061635	regulation of protein complex stability(GO:0061635)
0.7	15.6	GO:0032060	bleb assembly(GO:0032060)
0.7	7.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.7	17.7	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.7	5.9	GO:0031944	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.6	8.4	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6	26.1	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.6	16.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.6	16.8	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.6	14.9	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.5	3.8	GO:0000255	allantoin metabolic process(GO:0000255)
0.5	31.0	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.5	2.0	GO:0019249	lactate biosynthetic process(GO:0019249)
0.5	13.1	GO:0010226	response to lithium ion(GO:0010226)
0.5	9.4	GO:0032486	Rap protein signal transduction(GO:0032486)
0.5	2.7	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.4	3.5	GO:0045176	apical protein localization(GO:0045176)
0.4	5.2	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.4	9.5	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.4	4.3	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.4	8.4	GO:0016180	snRNA processing(GO:0016180)
0.4	29.1	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.4	3.6	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.4	20.4	GO:0032732	positive regulation of interleukin-1 production(GO:0032732)
0.3	4.7	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.3	10.6	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.3	2.2	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.3	4.2	GO:0038203	TORC2 signaling(GO:0038203)
0.3	27.4	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.3	5.5	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3	1.5	GO:0035645	enteric smooth muscle cell differentiation(GO:0035645)
0.3	6.8	GO:0030488	tRNA methylation(GO:0030488)
0.3	13.2	GO:0019433	triglyceride catabolic process(GO:0019433)
0.3	7.4	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.3	1.1	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2	7.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.2	2.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2	1.8	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2	5.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.2	2.9	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.2	10.6	GO:0046949	fatty-acyl-CoA biosynthetic process(GO:0046949)
0.2	1.9	GO:0097070	ductus arteriosus closure(GO:0097070)
0.2	8.0	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2	17.0	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.2	3.1	GO:0018345	protein palmitoylation(GO:0018345)
0.2	2.3	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.2	1.3	GO:0070543	response to linoleic acid(GO:0070543)
0.2	15.8	GO:0002181	cytoplasmic translation(GO:0002181)
0.1	5.5	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1	6.1	GO:0016266	O-glycan processing(GO:0016266)
0.1	10.6	GO:0006446	regulation of translational initiation(GO:0006446)
0.1	2.2	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1	0.6	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.1	4.3	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.1	0.8	GO:0070307	lens fiber cell development(GO:0070307)
0.1	2.6	GO:0060512	prostate gland morphogenesis(GO:0060512)
0.1	0.8	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1	6.6	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1	5.9	GO:0001895	retina homeostasis(GO:0001895)
0.1	1.3	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.1	2.0	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.3	GO:0019376	galactolipid catabolic process(GO:0019376)
0.1	2.9	GO:0034629	cellular protein complex localization(GO:0034629)
0.1	2.5	GO:0006308	DNA catabolic process(GO:0006308)
0.1	0.4	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	6.1	GO:0032392	DNA geometric change(GO:0032392)
0.1	11.9	GO:0046718	viral entry into host cell(GO:0046718)
0.1	2.4	GO:0061512	protein localization to cilium(GO:0061512)
0.1	0.3	GO:0033058	directional locomotion(GO:0033058)
0.0	4.1	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.3	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	14.8	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	2.4	GO:0006826	iron ion transport(GO:0006826)
0.0	0.7	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.7	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	4.8	GO:0008213	protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0	0.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	4.2	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0	0.2	GO:0010593	negative regulation of lamellipodium assembly(GO:0010593)
0.0	2.7	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	1.6	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.0	0.4	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	4.0	GO:0043687	post-translational protein modification(GO:0043687)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.1	45.4	GO:1990298	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
6.5	32.7	GO:0070557	PCNA-p21 complex(GO:0070557)
4.6	41.4	GO:0032133	chromosome passenger complex(GO:0032133)
4.3	69.5	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
4.3	21.6	GO:0031523	Myb complex(GO:0031523)
4.2	41.9	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
4.1	12.3	GO:0000799	nuclear condensin complex(GO:0000799)
2.9	28.7	GO:0097255	R2TP complex(GO:0097255)
2.5	10.1	GO:0005873	plus-end kinesin complex(GO:0005873)
2.3	35.1	GO:0031616	spindle pole centrosome(GO:0031616)
2.3	16.2	GO:0005610	laminin-5 complex(GO:0005610)
2.2	40.2	GO:0035631	CD40 receptor complex(GO:0035631)
2.2	6.6	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
2.0	12.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
1.9	7.7	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
1.8	9.0	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
1.8	8.9	GO:0042643	actomyosin, actin portion(GO:0042643)
1.7	5.2	GO:1902636	kinociliary basal body(GO:1902636)
1.7	11.8	GO:0097451	glial limiting end-foot(GO:0097451)
1.4	17.0	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
1.3	16.5	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
1.3	3.8	GO:0070195	growth hormone receptor complex(GO:0070195)
1.2	21.2	GO:0031080	nuclear pore outer ring(GO:0031080)
1.1	14.9	GO:0097413	Lewy body(GO:0097413)
1.1	8.0	GO:0005956	protein kinase CK2 complex(GO:0005956)
1.0	4.1	GO:0035841	new growing cell tip(GO:0035841)
1.0	4.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
1.0	7.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
1.0	17.9	GO:0033643	host cell part(GO:0033643)
1.0	70.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.8	8.4	GO:0032039	integrator complex(GO:0032039)
0.7	9.5	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.6	3.1	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.6	1.7	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.5	20.0	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.5	4.2	GO:0001520	outer dense fiber(GO:0001520)
0.5	34.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.4	62.7	GO:0005882	intermediate filament(GO:0005882)
0.4	3.5	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4	3.8	GO:0044754	autolysosome(GO:0044754)
0.4	9.0	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3	10.5	GO:0031528	microvillus membrane(GO:0031528)
0.3	17.1	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3	31.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.3	5.3	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2	9.1	GO:0031941	filamentous actin(GO:0031941)
0.2	8.4	GO:0099738	cell cortex region(GO:0099738)
0.2	4.2	GO:0031932	TORC2 complex(GO:0031932)
0.2	7.6	GO:0005859	muscle myosin complex(GO:0005859)
0.2	31.6	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.2	7.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	13.8	GO:0045178	basal part of cell(GO:0045178)
0.2	1.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.2	2.5	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.2	3.4	GO:0000242	pericentriolar material(GO:0000242)
0.2	9.4	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	1.9	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	4.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	4.9	GO:0036379	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1	2.8	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	2.6	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	5.1	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	18.5	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1	2.9	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	16.6	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.1	8.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	5.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	29.7	GO:0005759	mitochondrial matrix(GO:0005759)
0.1	1.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	6.7	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	10.6	GO:0032993	protein-DNA complex(GO:0032993)
0.1	8.0	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.1	1.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	30.5	GO:0005925	focal adhesion(GO:0005925)
0.1	2.5	GO:0035580	specific granule lumen(GO:0035580)
0.1	2.3	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	19.0	GO:0016607	nuclear speck(GO:0016607)
0.0	1.0	GO:0005657	replication fork(GO:0005657)
0.0	1.3	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.7	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.7	GO:0031904	endosome lumen(GO:0031904)
0.0	1.8	GO:0016605	PML body(GO:0016605)
0.0	1.3	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	18.2	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	5.8	GO:0000790	nuclear chromatin(GO:0000790)
0.0	1.1	GO:0055037	recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.4	31.3	GO:0098808	mRNA cap binding(GO:0098808)
7.2	36.1	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
7.0	27.9	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
6.5	32.7	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
5.7	28.7	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
5.3	15.8	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
5.2	20.6	GO:0004743	pyruvate kinase activity(GO:0004743)
4.9	79.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
4.4	79.7	GO:0001055	RNA polymerase II activity(GO:0001055)
4.3	21.6	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
3.4	10.3	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
3.2	9.5	GO:0051717	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
2.7	8.1	GO:0047315	kynurenine-glyoxylate transaminase activity(GO:0047315)
2.7	10.6	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
2.6	56.1	GO:0008494	translation activator activity(GO:0008494)
2.3	18.6	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
2.2	6.6	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
2.0	6.0	GO:0046577	long-chain-alcohol oxidase activity(GO:0046577)
1.8	14.5	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
1.7	10.5	GO:0034186	apolipoprotein A-I binding(GO:0034186)
1.4	6.8	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
1.4	8.2	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
1.3	5.2	GO:0002046	opsin binding(GO:0002046)
1.2	16.3	GO:0046790	virion binding(GO:0046790)
0.9	7.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.9	5.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9	26.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.9	17.9	GO:0032036	myosin heavy chain binding(GO:0032036)
0.8	9.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.7	3.4	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.7	4.7	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.7	14.7	GO:0008266	poly(U) RNA binding(GO:0008266)
0.7	17.6	GO:0000400	four-way junction DNA binding(GO:0000400)
0.6	3.9	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.6	17.0	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6	16.7	GO:0071949	FAD binding(GO:0071949)
0.6	10.8	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.5	4.3	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.5	18.5	GO:0001972	retinoic acid binding(GO:0001972)
0.5	1.9	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.5	14.9	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.5	2.8	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.5	16.5	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.5	5.9	GO:1990239	steroid hormone binding(GO:1990239)
0.4	7.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.4	5.3	GO:0035240	dopamine binding(GO:0035240)
0.4	6.1	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4	1.8	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.3	7.5	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.3	2.5	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.3	4.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.3	5.1	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.3	2.0	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.3	16.0	GO:0048487	beta-tubulin binding(GO:0048487)
0.3	17.8	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.3	7.6	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3	4.1	GO:0030957	Tat protein binding(GO:0030957)
0.3	1.3	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2	51.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.2	11.2	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.2	10.6	GO:0001221	transcription cofactor binding(GO:0001221)
0.2	3.5	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.2	13.2	GO:0005504	fatty acid binding(GO:0005504)
0.2	1.5	GO:0004962	endothelin receptor activity(GO:0004962)
0.2	15.3	GO:0019003	GDP binding(GO:0019003)
0.2	2.7	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.2	23.3	GO:0043130	ubiquitin binding(GO:0043130)
0.2	10.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.2	1.3	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.2	3.8	GO:0070064	proline-rich region binding(GO:0070064)
0.2	1.1	GO:0089720	caspase binding(GO:0089720)
0.2	7.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.2	9.5	GO:0042379	chemokine receptor binding(GO:0042379)
0.1	2.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	4.3	GO:0005123	death receptor binding(GO:0005123)
0.1	1.7	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.4	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1	4.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	2.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	9.0	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.1	12.1	GO:0008276	protein methyltransferase activity(GO:0008276)
0.1	4.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	0.3	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1	20.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	0.3	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1	2.9	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	3.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	5.6	GO:0070888	E-box binding(GO:0070888)
0.1	2.6	GO:0042056	chemoattractant activity(GO:0042056)
0.1	5.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	10.7	GO:0005125	cytokine activity(GO:0005125)
0.1	8.0	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.1	2.4	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.6	GO:0008097	5S rRNA binding(GO:0008097)
0.1	1.9	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	3.1	GO:0050681	androgen receptor binding(GO:0050681)
0.1	5.8	GO:0051087	chaperone binding(GO:0051087)
0.1	0.6	GO:0043295	glutathione binding(GO:0043295)
0.1	4.1	GO:0003777	microtubule motor activity(GO:0003777)
0.1	0.7	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0	0.2	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	8.4	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	4.7	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.6	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.3	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	4.1	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.4	GO:0002162	dystroglycan binding(GO:0002162)
0.0	1.1	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	16.9	GO:0005509	calcium ion binding(GO:0005509)
0.0	6.6	GO:0005525	GTP binding(GO:0005525)
0.0	5.5	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0	2.1	GO:0042393	histone binding(GO:0042393)
0.0	1.3	GO:0020037	heme binding(GO:0020037)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	32.7	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.8	59.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
1.1	62.6	PID AURORA B PATHWAY	Aurora B signaling
0.9	16.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.7	62.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.7	28.7	PID MYC PATHWAY	C-MYC pathway
0.5	9.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.4	17.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.4	22.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.4	40.9	PID P73PATHWAY	p73 transcription factor network
0.4	26.3	PID P53 REGULATION PATHWAY	p53 pathway
0.4	32.0	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.3	25.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3	8.0	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.2	8.4	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.2	6.7	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	4.2	PID ATM PATHWAY	ATM pathway
0.1	7.7	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	2.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	13.5	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	4.2	PID PLK1 PATHWAY	PLK1 signaling events
0.1	3.8	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	2.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	78.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
2.7	16.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
2.4	9.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
1.8	60.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.6	45.4	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.4	16.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.3	28.7	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
1.3	61.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
1.0	14.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.8	19.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.8	59.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.8	29.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.7	22.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.7	18.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.6	22.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.6	32.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.6	16.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.4	10.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.4	8.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.4	9.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4	7.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4	31.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.4	18.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.4	10.1	REACTOME KINESINS	Genes involved in Kinesins
0.3	3.8	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.3	9.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	7.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.3	17.0	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.2	23.8	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	3.5	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	2.7	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.2	3.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	5.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	4.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.2	7.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	6.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	15.5	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	6.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.1	3.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	4.4	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	14.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	3.9	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	2.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	4.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	1.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.0	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	9.4	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	5.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	3.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	2.3	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions

Results for TP63

Z-value: 1.46

Motif logo

Transcription factors associated with TP63

Activity-expression correlation:

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: