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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for UAAGACG
Z-value: 0.23
Motif logo
miRNA associated with seed UAAGACG
Network of associatons between targets according to the STRING database.
First level regulatory network of UAAGACG
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_43286512 Show fit | 1.79 |
ENST00000454177.5
ENST00000429705.6 ENST00000296088.12 ENST00000437827.1 |
SNF related kinase |
|
| chr3_-_18425295 Show fit | 1.49 |
ENST00000338745.11
ENST00000450898.1 |
SATB homeobox 1 |
|
| chr1_-_107965009 Show fit | 1.45 |
ENST00000527011.5
ENST00000370056.9 |
vav guanine nucleotide exchange factor 3 |
|
| chr12_-_92145838 Show fit | 1.38 |
ENST00000256015.5
|
BTG anti-proliferation factor 1 |
|
| chr6_+_21593742 Show fit | 1.34 |
ENST00000244745.4
|
SRY-box transcription factor 4 |
|
| chr5_+_122775062 Show fit | 1.29 |
ENST00000379516.7
ENST00000505934.5 ENST00000514949.1 |
sorting nexin 2 |
|
| chr8_+_55102012 Show fit | 1.28 |
ENST00000327381.7
|
XK related 4 |
|
| chr13_+_49997019 Show fit | 1.27 |
ENST00000420995.6
ENST00000356017.8 ENST00000378182.4 ENST00000457662.2 |
tripartite motif containing 13 |
|
| chr14_-_21269451 Show fit | 1.27 |
ENST00000336053.10
|
heterogeneous nuclear ribonucleoprotein C |
|
| chr2_+_119759875 Show fit | 1.21 |
ENST00000263708.7
|
protein tyrosine phosphatase non-receptor type 4 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.1 | 1.5 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 1.5 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.1 | 1.4 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.3 | 1.3 | GO:0035905 | N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.1 | 1.3 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 1.3 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.1 | 1.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.4 | 1.1 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.4 | 1.1 | GO:0036446 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.2 | 1.3 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.1 | 1.3 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 1.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 1.0 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.1 | 1.0 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.0 | 1.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 1.0 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.9 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 0.8 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.2 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 1.5 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.3 | 1.3 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.1 | 1.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 1.3 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 1.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.4 | 1.1 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.1 | 1.1 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 1.1 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 1.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 1.5 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 1.5 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 1.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.3 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 1.1 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.2 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 1.5 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 1.5 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.5 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.7 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 0.5 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.4 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |