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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for UAAGGCA
Z-value: 0.84
Motif logo
miRNA associated with seed UAAGGCA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-124-3p.2
|
|
|
hsa-miR-506-3p
|
Activity profile of UAAGGCA motif
Sorted Z-values of UAAGGCA motif
Network of associatons between targets according to the STRING database.
First level regulatory network of UAAGGCA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 10.1 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 3.0 | 12.0 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 2.5 | 7.5 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 2.4 | 7.1 | GO:0034402 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402) |
| 2.2 | 8.7 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 2.0 | 8.2 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 2.0 | 7.8 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 1.8 | 5.5 | GO:0021592 | fourth ventricle development(GO:0021592) third ventricle development(GO:0021678) |
| 1.7 | 13.6 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 1.7 | 5.1 | GO:1901355 | response to rapamycin(GO:1901355) |
| 1.7 | 8.4 | GO:1904637 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 1.7 | 10.0 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 1.7 | 5.0 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 1.6 | 6.6 | GO:0036135 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) negative regulation of glial cell migration(GO:1903976) |
| 1.6 | 3.2 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 1.6 | 12.7 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 1.5 | 6.2 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 1.5 | 8.9 | GO:0033489 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 1.5 | 4.4 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 1.5 | 7.3 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 1.4 | 5.6 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 1.4 | 4.2 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 1.3 | 9.2 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 1.3 | 5.2 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 1.2 | 4.9 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 1.2 | 7.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 1.2 | 3.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 1.2 | 3.5 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 1.2 | 3.5 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 1.2 | 3.5 | GO:0042823 | pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) |
| 1.1 | 11.3 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 1.1 | 5.6 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 1.1 | 7.7 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 1.0 | 7.3 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 1.0 | 6.0 | GO:0008218 | bioluminescence(GO:0008218) |
| 1.0 | 5.9 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.9 | 3.7 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 0.9 | 2.8 | GO:0021896 | forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) |
| 0.9 | 3.6 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.9 | 3.5 | GO:0048378 | tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) |
| 0.9 | 5.2 | GO:0015853 | adenine transport(GO:0015853) |
| 0.9 | 8.6 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 0.9 | 5.2 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.8 | 18.6 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.8 | 2.5 | GO:0071934 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 0.8 | 16.4 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.8 | 4.9 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.8 | 5.6 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.8 | 3.1 | GO:0061073 | ciliary body morphogenesis(GO:0061073) endocardial cushion cell differentiation(GO:0061443) |
| 0.8 | 3.9 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.8 | 7.7 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.8 | 9.1 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.8 | 2.3 | GO:0010520 | regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903) |
| 0.8 | 5.3 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 0.7 | 4.4 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.7 | 3.6 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.7 | 5.7 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.7 | 12.5 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.7 | 13.1 | GO:0070831 | basement membrane assembly(GO:0070831) |
| 0.7 | 4.8 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
| 0.7 | 2.7 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.7 | 2.0 | GO:2000687 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.6 | 2.6 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.6 | 2.5 | GO:0097102 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.6 | 2.5 | GO:0009838 | abscission(GO:0009838) |
| 0.6 | 5.0 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.6 | 7.5 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.6 | 7.1 | GO:0051665 | membrane raft localization(GO:0051665) |
| 0.6 | 3.0 | GO:1904398 | positive regulation of neuromuscular junction development(GO:1904398) |
| 0.6 | 2.3 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.6 | 4.5 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 0.6 | 8.9 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.6 | 3.3 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.5 | 2.7 | GO:0071233 | cellular response to leucine(GO:0071233) |
| 0.5 | 4.8 | GO:0044598 | polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
| 0.5 | 6.0 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.5 | 4.9 | GO:1904903 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.5 | 5.8 | GO:1904754 | positive regulation of vascular associated smooth muscle cell migration(GO:1904754) |
| 0.5 | 7.7 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) |
| 0.5 | 8.5 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.5 | 3.7 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 0.5 | 2.3 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 0.5 | 5.1 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.5 | 10.0 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.4 | 10.6 | GO:0051923 | sulfation(GO:0051923) |
| 0.4 | 2.2 | GO:0050428 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.4 | 2.1 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.4 | 2.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.4 | 3.7 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.4 | 3.6 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.4 | 4.8 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.4 | 2.7 | GO:0010044 | response to aluminum ion(GO:0010044) |
| 0.4 | 7.7 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.4 | 5.1 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.4 | 2.5 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.4 | 1.4 | GO:0034670 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.4 | 3.2 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.4 | 0.7 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 0.4 | 1.4 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.3 | 2.1 | GO:0090625 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.3 | 2.1 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.3 | 3.4 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.3 | 2.0 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.3 | 1.3 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 0.3 | 9.1 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.3 | 8.2 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.3 | 4.2 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.3 | 2.3 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.3 | 1.3 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.3 | 7.8 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.3 | 3.7 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.3 | 7.3 | GO:0051770 | positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770) |
| 0.3 | 1.2 | GO:0035750 | protein localization to myelin sheath abaxonal region(GO:0035750) |
| 0.3 | 4.7 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.3 | 2.3 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.3 | 2.1 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 0.3 | 1.2 | GO:1904502 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
| 0.3 | 2.9 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.3 | 4.0 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.3 | 2.0 | GO:0015677 | copper ion import(GO:0015677) |
| 0.3 | 3.0 | GO:0021740 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.3 | 0.8 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.3 | 4.2 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.3 | 2.1 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.3 | 0.8 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.3 | 8.4 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.3 | 4.3 | GO:0000212 | meiotic spindle organization(GO:0000212) |
| 0.3 | 0.5 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
| 0.2 | 1.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.2 | 2.4 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
| 0.2 | 6.7 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.2 | 0.7 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 0.2 | 1.8 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.2 | 2.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.2 | 2.2 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
| 0.2 | 2.9 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 0.2 | 0.7 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 0.2 | 1.1 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.2 | 4.1 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.2 | 4.3 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.2 | 1.9 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.2 | 4.0 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.2 | 2.3 | GO:0003360 | brainstem development(GO:0003360) |
| 0.2 | 0.6 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.2 | 3.5 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.2 | 1.6 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.2 | 1.8 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.2 | 5.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.2 | 2.3 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.2 | 1.1 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.2 | 13.4 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.2 | 2.0 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.2 | 0.4 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.2 | 5.1 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.2 | 0.5 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.2 | 0.5 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 0.2 | 0.5 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 0.2 | 1.0 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.2 | 4.3 | GO:0048846 | axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284) |
| 0.2 | 2.8 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.2 | 1.5 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.2 | 0.5 | GO:0036233 | glycine import(GO:0036233) |
| 0.2 | 1.7 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.2 | 4.4 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.1 | 6.6 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.1 | 6.0 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.1 | 1.6 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.1 | 4.1 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.1 | 2.5 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.1 | 4.3 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 1.4 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.1 | 0.7 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.1 | 4.0 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.1 | 2.0 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.1 | 0.6 | GO:0006551 | leucine metabolic process(GO:0006551) |
| 0.1 | 1.7 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 0.1 | 1.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 0.9 | GO:1903659 | regulation of complement-dependent cytotoxicity(GO:1903659) |
| 0.1 | 0.7 | GO:0097647 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.1 | 0.6 | GO:2001271 | regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.1 | 0.1 | GO:1901896 | positive regulation of calcium-transporting ATPase activity(GO:1901896) |
| 0.1 | 2.5 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
| 0.1 | 0.8 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.1 | 3.1 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.1 | 10.4 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.1 | 1.0 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.1 | 0.9 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.1 | 0.7 | GO:0032506 | cytokinetic process(GO:0032506) |
| 0.1 | 0.4 | GO:0060940 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.1 | 3.0 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.1 | 0.8 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 0.5 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 0.1 | 1.4 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.1 | 1.9 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.1 | 0.8 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
| 0.1 | 4.7 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
| 0.1 | 1.1 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.1 | 1.0 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.1 | 0.6 | GO:0048840 | otolith development(GO:0048840) |
| 0.1 | 2.0 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.1 | 0.4 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.1 | 0.7 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.1 | 6.4 | GO:0032465 | regulation of cytokinesis(GO:0032465) |
| 0.1 | 4.2 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.1 | 6.1 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.1 | 2.6 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.1 | 3.3 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.1 | 3.3 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.1 | 3.3 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.1 | 4.7 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 3.8 | GO:0046949 | fatty-acyl-CoA biosynthetic process(GO:0046949) |
| 0.1 | 1.3 | GO:0060117 | auditory receptor cell development(GO:0060117) |
| 0.1 | 2.0 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.1 | 0.4 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
| 0.1 | 2.8 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.1 | 0.8 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.1 | 5.1 | GO:0010812 | negative regulation of cell-substrate adhesion(GO:0010812) |
| 0.1 | 0.5 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.1 | 5.0 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 0.1 | 1.3 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.1 | 0.8 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
| 0.1 | 2.1 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.1 | 4.2 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 4.1 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.1 | 3.1 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.1 | 0.5 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.0 | 2.5 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 3.0 | GO:0000271 | polysaccharide biosynthetic process(GO:0000271) |
| 0.0 | 0.4 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.0 | 0.7 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.0 | 3.0 | GO:0070671 | interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349) |
| 0.0 | 1.4 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.0 | 2.3 | GO:0043486 | histone exchange(GO:0043486) |
| 0.0 | 0.4 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 0.5 | GO:2000615 | histone H3-K9 acetylation(GO:0043970) regulation of histone H3-K9 acetylation(GO:2000615) |
| 0.0 | 1.7 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 0.3 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 2.0 | GO:0033260 | nuclear DNA replication(GO:0033260) |
| 0.0 | 1.5 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 0.2 | GO:0046621 | negative regulation of organ growth(GO:0046621) |
| 0.0 | 6.2 | GO:0042594 | response to starvation(GO:0042594) |
| 0.0 | 0.2 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 0.0 | 1.0 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.0 | 8.8 | GO:0006260 | DNA replication(GO:0006260) |
| 0.0 | 5.3 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.0 | 1.9 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 2.4 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.4 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.0 | 2.2 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 0.4 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.0 | 0.3 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 0.0 | 2.1 | GO:0042116 | macrophage activation(GO:0042116) |
| 0.0 | 0.1 | GO:0042946 | glucoside transport(GO:0042946) |
| 0.0 | 0.1 | GO:0045634 | regulation of melanocyte differentiation(GO:0045634) |
| 0.0 | 0.3 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 2.8 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 0.4 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.0 | 0.3 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.2 | GO:0071545 | inositol phosphate catabolic process(GO:0071545) |
| 0.0 | 1.2 | GO:0031102 | neuron projection regeneration(GO:0031102) |
| 0.0 | 1.3 | GO:0030888 | regulation of B cell proliferation(GO:0030888) |
| 0.0 | 2.0 | GO:0018410 | C-terminal protein amino acid modification(GO:0018410) |
| 0.0 | 1.8 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.0 | 3.9 | GO:0002433 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
| 0.0 | 1.4 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 0.3 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.0 | 1.6 | GO:0006305 | DNA alkylation(GO:0006305) DNA methylation(GO:0006306) |
| 0.0 | 3.5 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 1.0 | GO:0090307 | mitotic spindle assembly(GO:0090307) |
| 0.0 | 6.9 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.0 | 0.3 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.2 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.0 | 2.0 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
| 0.0 | 0.1 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.0 | 3.7 | GO:0006413 | translational initiation(GO:0006413) |
| 0.0 | 0.3 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 0.8 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 0.4 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.5 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
| 0.0 | 0.2 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.4 | GO:0045682 | regulation of epidermis development(GO:0045682) |
| 0.0 | 0.1 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 13.4 | GO:0072563 | endothelial microparticle(GO:0072563) |
| 3.6 | 10.7 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
| 2.2 | 6.5 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 2.1 | 10.5 | GO:0097513 | myosin II filament(GO:0097513) |
| 2.0 | 6.1 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 1.3 | 12.7 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 1.3 | 1.3 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 1.1 | 3.4 | GO:0055087 | Ski complex(GO:0055087) |
| 1.1 | 4.2 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.9 | 6.6 | GO:0016589 | NURF complex(GO:0016589) |
| 0.9 | 5.6 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.9 | 14.7 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.9 | 4.4 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.9 | 4.4 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.9 | 4.3 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.8 | 8.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.7 | 3.7 | GO:0044094 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 0.7 | 3.7 | GO:0044308 | axonal spine(GO:0044308) |
| 0.7 | 3.6 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.7 | 7.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.7 | 5.5 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.7 | 8.2 | GO:0071203 | F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203) |
| 0.7 | 7.4 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.7 | 7.2 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.6 | 5.1 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.6 | 4.4 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.6 | 3.7 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.6 | 15.2 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.6 | 3.3 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
| 0.5 | 6.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.5 | 4.4 | GO:0090543 | Flemming body(GO:0090543) |
| 0.4 | 2.7 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.4 | 13.1 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.4 | 10.0 | GO:0046930 | pore complex(GO:0046930) |
| 0.4 | 4.9 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.4 | 4.7 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.3 | 5.9 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.3 | 10.8 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.3 | 3.2 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.3 | 1.9 | GO:0005879 | axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279) |
| 0.3 | 0.6 | GO:0000805 | X chromosome(GO:0000805) |
| 0.3 | 11.9 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.3 | 1.2 | GO:0031211 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.3 | 1.4 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.3 | 25.0 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.3 | 2.8 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.3 | 8.6 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.3 | 17.2 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.3 | 8.4 | GO:0033176 | proton-transporting V-type ATPase complex(GO:0033176) |
| 0.3 | 2.4 | GO:0045180 | basal cortex(GO:0045180) |
| 0.3 | 19.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.2 | 2.1 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.2 | 2.1 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.2 | 1.4 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.2 | 12.6 | GO:0002102 | podosome(GO:0002102) |
| 0.2 | 1.3 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.2 | 4.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.2 | 2.6 | GO:0001741 | XY body(GO:0001741) |
| 0.2 | 2.0 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.2 | 3.5 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.2 | 2.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.2 | 1.7 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 0.2 | 0.8 | GO:0071920 | cleavage body(GO:0071920) |
| 0.2 | 2.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.2 | 1.7 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.2 | 15.0 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.2 | 2.0 | GO:0070449 | elongin complex(GO:0070449) |
| 0.2 | 23.4 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.2 | 5.0 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.2 | 5.3 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.2 | 2.1 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 1.4 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.2 | 0.5 | GO:0034455 | t-UTP complex(GO:0034455) |
| 0.2 | 5.2 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.2 | 4.0 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.2 | 2.8 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.2 | 1.3 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.2 | 3.7 | GO:0005605 | basal lamina(GO:0005605) |
| 0.2 | 2.3 | GO:0032059 | bleb(GO:0032059) |
| 0.2 | 2.9 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 1.2 | GO:0043219 | lateral loop(GO:0043219) |
| 0.1 | 0.7 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.1 | 7.8 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 3.0 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 13.9 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 0.4 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.1 | 3.7 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 2.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 7.0 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.1 | 7.4 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 2.3 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 4.0 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.1 | 3.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 1.2 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 3.1 | GO:0005921 | gap junction(GO:0005921) |
| 0.1 | 0.8 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 11.5 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 3.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 3.3 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.1 | 5.5 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.1 | 2.6 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 1.7 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.1 | 7.1 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.1 | 4.3 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 9.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 0.4 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.1 | 4.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 1.7 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 20.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 3.5 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.1 | 0.7 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.1 | 2.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 1.0 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 1.1 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.1 | 0.6 | GO:0034385 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.1 | 1.0 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 1.5 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 4.4 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 3.2 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 1.4 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 2.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.9 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 2.4 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 11.3 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 1.0 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 2.0 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 17.2 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 2.0 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 2.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.7 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 1.7 | GO:0044439 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439) |
| 0.0 | 1.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 2.2 | GO:0031514 | motile cilium(GO:0031514) |
| 0.0 | 4.6 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 8.3 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 1.6 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 4.0 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 1.0 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 7.9 | GO:0031252 | cell leading edge(GO:0031252) |
| 0.0 | 3.1 | GO:0034774 | secretory granule lumen(GO:0034774) |
| 0.0 | 1.5 | GO:0031970 | organelle envelope lumen(GO:0031970) |
| 0.0 | 0.5 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 10.3 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 3.3 | 10.0 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 3.3 | 16.4 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 3.0 | 12.0 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 2.4 | 7.1 | GO:0031755 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 2.2 | 8.9 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 1.9 | 7.5 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 1.9 | 5.6 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 1.8 | 7.2 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 1.7 | 5.0 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 1.5 | 7.7 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 1.5 | 4.4 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 1.4 | 4.3 | GO:0032427 | GBD domain binding(GO:0032427) |
| 1.4 | 7.0 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 1.4 | 4.2 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 1.4 | 6.8 | GO:0047280 | nicotinamide phosphoribosyltransferase activity(GO:0047280) |
| 1.3 | 4.0 | GO:0055100 | adiponectin binding(GO:0055100) |
| 1.3 | 6.7 | GO:0010340 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 1.3 | 10.0 | GO:0015288 | porin activity(GO:0015288) |
| 1.2 | 4.9 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 1.2 | 7.3 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 1.2 | 3.5 | GO:0031403 | lithium ion binding(GO:0031403) |
| 1.1 | 7.5 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.9 | 2.8 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.9 | 6.6 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.9 | 4.5 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.8 | 2.5 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.8 | 10.7 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.8 | 4.8 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.8 | 7.7 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.7 | 3.6 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 0.7 | 2.1 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.7 | 2.7 | GO:0070404 | NADH binding(GO:0070404) |
| 0.7 | 3.3 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
| 0.6 | 6.5 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.6 | 3.2 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.6 | 4.1 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.5 | 12.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.5 | 5.2 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 0.5 | 13.4 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 0.5 | 1.8 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 0.4 | 1.3 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.4 | 6.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.4 | 11.3 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.4 | 3.2 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.4 | 4.7 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.4 | 5.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.4 | 1.2 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.4 | 15.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.4 | 10.0 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.4 | 3.0 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.4 | 26.2 | GO:0019003 | GDP binding(GO:0019003) |
| 0.4 | 2.2 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.3 | 8.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.3 | 2.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.3 | 5.4 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.3 | 2.5 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.3 | 0.9 | GO:0004008 | copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682) |
| 0.3 | 4.7 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.3 | 5.2 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.3 | 0.9 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 0.3 | 2.3 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.3 | 1.2 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 0.3 | 2.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.3 | 8.9 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 0.3 | 13.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.3 | 1.7 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.3 | 1.4 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.3 | 7.8 | GO:0071949 | FAD binding(GO:0071949) |
| 0.3 | 5.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.3 | 8.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.3 | 2.4 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.3 | 8.5 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.3 | 1.3 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.2 | 3.7 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.2 | 1.4 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.2 | 5.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 0.7 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.2 | 4.9 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.2 | 18.7 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.2 | 7.9 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.2 | 2.8 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.2 | 6.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.2 | 1.7 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 0.2 | 2.3 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.2 | 7.9 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.2 | 3.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 10.5 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.2 | 1.3 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.2 | 1.7 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.2 | 4.1 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 4.2 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.2 | 4.0 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.2 | 4.9 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.2 | 2.5 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.2 | 3.9 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.2 | 1.6 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.2 | 4.4 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.2 | 0.5 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.2 | 0.7 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.2 | 6.0 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.2 | 2.0 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.2 | 0.5 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.2 | 2.0 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 2.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 3.3 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 2.5 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.1 | 1.4 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.1 | 9.6 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.1 | 2.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 7.9 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 0.8 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.1 | 2.5 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 2.8 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 5.0 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 1.3 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 3.2 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.1 | 0.6 | GO:0052656 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 0.5 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.1 | 1.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 7.3 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.1 | 10.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.7 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.1 | 1.8 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 0.3 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.1 | 0.4 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.1 | 7.5 | GO:0051287 | NAD binding(GO:0051287) |
| 0.1 | 13.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.1 | 0.9 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 0.1 | 2.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 2.4 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 0.6 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 0.1 | 2.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 1.2 | GO:0048185 | activin binding(GO:0048185) |
| 0.1 | 2.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 2.1 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.1 | 2.9 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.1 | 0.7 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 0.4 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 0.1 | 0.8 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.1 | 1.9 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 30.3 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 1.7 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 1.3 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.1 | 6.8 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.1 | 1.3 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 2.3 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 0.5 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.1 | 1.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 10.7 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 1.6 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.1 | 0.3 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.1 | 1.0 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.1 | 0.9 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 0.7 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 2.9 | GO:0004527 | exonuclease activity(GO:0004527) |
| 0.0 | 0.1 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.0 | 5.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 2.7 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035) |
| 0.0 | 10.3 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.3 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 0.0 | 0.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 2.2 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.7 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.0 | 0.2 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.0 | 0.7 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.0 | 2.4 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.0 | 0.1 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.0 | 0.1 | GO:0042947 | glucoside transmembrane transporter activity(GO:0042947) |
| 0.0 | 0.4 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.0 | 1.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 8.2 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.3 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.4 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 2.1 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 3.9 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.4 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 3.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.2 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 3.0 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.7 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 0.0 | 0.5 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.6 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.5 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 2.5 | GO:0003714 | transcription corepressor activity(GO:0003714) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 10.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.4 | 11.2 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.4 | 8.4 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.3 | 6.8 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.3 | 19.6 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.2 | 10.1 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 10.7 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.2 | 7.5 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.2 | 6.4 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.2 | 7.1 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.2 | 2.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.2 | 3.7 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.2 | 9.7 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.2 | 11.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 5.0 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 6.4 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 5.3 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 6.8 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 5.6 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 4.8 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.1 | 21.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 5.3 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 5.2 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 1.0 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.1 | 11.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 7.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 1.5 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 5.2 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 3.1 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 3.7 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 0.5 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 3.3 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 11.4 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.6 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 2.4 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.5 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.0 | 4.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.3 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 2.1 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.5 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 1.7 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.6 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.4 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.7 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 8.9 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.5 | 13.1 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.5 | 5.5 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.5 | 6.8 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.5 | 3.4 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.5 | 7.2 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.5 | 8.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.4 | 5.2 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.4 | 8.2 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.3 | 8.6 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.3 | 10.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.3 | 13.4 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.3 | 8.4 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.3 | 5.9 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.3 | 3.1 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.3 | 6.6 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.3 | 7.8 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.2 | 4.9 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.2 | 6.0 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.2 | 8.4 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.2 | 4.7 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.2 | 8.9 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.2 | 1.7 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.2 | 4.2 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.2 | 2.3 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.2 | 27.8 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.2 | 8.0 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.2 | 5.8 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.2 | 6.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 3.3 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 4.7 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 2.3 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.1 | 9.6 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 3.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 5.6 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 5.5 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.1 | 4.4 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 1.0 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 7.2 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.1 | 1.6 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 2.8 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 3.0 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.1 | 2.3 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 1.4 | REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | Genes involved in Nuclear Events (kinase and transcription factor activation) |
| 0.1 | 3.3 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.1 | 5.9 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 2.2 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.1 | 0.6 | REACTOME SIGNALING BY EGFR IN CANCER | Genes involved in Signaling by EGFR in Cancer |
| 0.1 | 8.2 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.1 | 5.5 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 1.7 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.1 | 2.2 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 3.7 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 0.5 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 3.7 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 5.3 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 1.3 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.4 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 2.0 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 6.0 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.7 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.1 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.9 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.3 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.7 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 1.4 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 0.3 | REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.0 | 0.2 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.1 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.0 | 0.5 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.0 | 2.0 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |