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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for UACAGUA
Z-value: 0.55
Motif logo
miRNA associated with seed UACAGUA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-101-3p.2
|
Activity profile of UACAGUA motif
Sorted Z-values of UACAGUA motif
Network of associatons between targets according to the STRING database.
First level regulatory network of UACAGUA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 6.1 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 1.5 | 4.4 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 1.4 | 4.2 | GO:1902269 | positive regulation of polyamine transmembrane transport(GO:1902269) |
| 1.3 | 4.0 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 1.3 | 3.8 | GO:1902822 | regulation of late endosome to lysosome transport(GO:1902822) |
| 1.2 | 3.6 | GO:0010752 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752) |
| 1.0 | 2.9 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 0.9 | 3.6 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.8 | 5.1 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874) |
| 0.8 | 5.0 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.8 | 3.2 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.8 | 3.2 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.8 | 2.4 | GO:0006113 | fermentation(GO:0006113) regulation of fermentation(GO:0043465) |
| 0.8 | 3.1 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.8 | 3.1 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.7 | 3.4 | GO:0044789 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.6 | 2.6 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.6 | 3.6 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.5 | 2.1 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.5 | 2.0 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.5 | 6.6 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.5 | 2.0 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 0.5 | 3.0 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.5 | 2.0 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 0.5 | 6.9 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.5 | 1.9 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.5 | 2.9 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.5 | 1.4 | GO:0045645 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 0.5 | 1.9 | GO:0035509 | negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.4 | 3.5 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.4 | 1.3 | GO:0090176 | microtubule cytoskeleton organization involved in establishment of planar polarity(GO:0090176) |
| 0.4 | 1.2 | GO:1901355 | response to rapamycin(GO:1901355) |
| 0.4 | 1.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.4 | 3.5 | GO:0060613 | fat pad development(GO:0060613) |
| 0.4 | 3.5 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.4 | 3.5 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.4 | 4.5 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.4 | 2.6 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.4 | 1.5 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.4 | 6.6 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.4 | 2.9 | GO:0003150 | muscular septum morphogenesis(GO:0003150) |
| 0.4 | 1.4 | GO:0010645 | regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) |
| 0.4 | 1.4 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.4 | 1.4 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.3 | 4.9 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.3 | 4.8 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.3 | 4.4 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.3 | 0.9 | GO:0097069 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 0.3 | 0.9 | GO:0003175 | tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) |
| 0.3 | 0.9 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.3 | 3.9 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.3 | 0.9 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) regulation of centriole elongation(GO:1903722) |
| 0.3 | 5.6 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.3 | 2.0 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.3 | 1.1 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.3 | 2.6 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.3 | 1.3 | GO:0006344 | optic cup formation involved in camera-type eye development(GO:0003408) maintenance of chromatin silencing(GO:0006344) |
| 0.3 | 2.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.3 | 0.8 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.3 | 1.3 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.3 | 1.3 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.2 | 2.2 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.2 | 2.4 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.2 | 1.2 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
| 0.2 | 2.6 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.2 | 1.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.2 | 1.2 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.2 | 2.5 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
| 0.2 | 4.2 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.2 | 0.4 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 0.2 | 0.8 | GO:0034670 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.2 | 1.9 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.2 | 2.1 | GO:2000576 | positive regulation of microtubule motor activity(GO:2000576) |
| 0.2 | 2.9 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.2 | 2.3 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.2 | 0.9 | GO:0048861 | oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861) |
| 0.2 | 0.9 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.2 | 1.8 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.2 | 1.6 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.2 | 1.7 | GO:0070495 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.2 | 6.2 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.2 | 2.7 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.2 | 1.0 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.2 | 0.8 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 0.2 | 1.3 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.2 | 1.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.2 | 3.2 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.1 | 1.6 | GO:2000795 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.1 | 1.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 4.0 | GO:0048846 | axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284) |
| 0.1 | 1.2 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.1 | 0.8 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.1 | 0.4 | GO:0098582 | innate vocalization behavior(GO:0098582) |
| 0.1 | 1.0 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.1 | 1.1 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 0.7 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.1 | 1.0 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 0.1 | 0.4 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.1 | 7.5 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.1 | 1.2 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.1 | 0.4 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.1 | 0.8 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.1 | 0.8 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.1 | 0.4 | GO:0035750 | protein localization to myelin sheath abaxonal region(GO:0035750) |
| 0.1 | 1.6 | GO:0051195 | negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198) |
| 0.1 | 0.9 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.1 | 0.6 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.1 | 0.2 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.1 | 1.4 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.1 | 1.5 | GO:1902916 | positive regulation of protein polyubiquitination(GO:1902916) |
| 0.1 | 0.3 | GO:1901859 | late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) |
| 0.1 | 0.6 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.1 | 7.1 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.1 | 0.4 | GO:0070460 | thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612) |
| 0.1 | 0.8 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.1 | 0.6 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 0.1 | 0.8 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.1 | 0.3 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.1 | 3.3 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.1 | 1.4 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.1 | 2.2 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.1 | 2.3 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.1 | 0.6 | GO:1904849 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.1 | 0.7 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.1 | 3.3 | GO:0099601 | regulation of neurotransmitter receptor activity(GO:0099601) |
| 0.1 | 0.4 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.1 | 2.6 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.1 | 0.4 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.1 | 1.1 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.1 | 0.3 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.1 | 0.2 | GO:0060437 | lung growth(GO:0060437) |
| 0.1 | 2.6 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
| 0.1 | 0.6 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.1 | 0.4 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 0.1 | 0.9 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 0.3 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.1 | 0.4 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.1 | 0.3 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 0.1 | 7.0 | GO:0045445 | myoblast differentiation(GO:0045445) |
| 0.1 | 1.1 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 3.6 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
| 0.1 | 0.6 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.1 | 3.7 | GO:0051058 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.1 | 0.6 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.1 | 0.2 | GO:0021764 | amygdala development(GO:0021764) |
| 0.1 | 1.3 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.1 | 1.8 | GO:0061641 | chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.1 | 0.2 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.1 | 0.7 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.1 | 0.3 | GO:0045586 | regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643) |
| 0.1 | 3.6 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 0.1 | 5.1 | GO:0045638 | negative regulation of myeloid cell differentiation(GO:0045638) |
| 0.0 | 0.8 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 2.1 | GO:0046039 | GTP metabolic process(GO:0046039) |
| 0.0 | 2.7 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.4 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.0 | 0.9 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 1.2 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 0.2 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 2.6 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.7 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.0 | 0.7 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 0.2 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 0.0 | 0.1 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 0.0 | 0.7 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.0 | 0.8 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
| 0.0 | 0.5 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.0 | 1.7 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.3 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.0 | 3.0 | GO:0006446 | regulation of translational initiation(GO:0006446) |
| 0.0 | 0.7 | GO:0048490 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 1.3 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.0 | 0.1 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 0.0 | 1.4 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 2.1 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.3 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.0 | 0.8 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 1.7 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 3.1 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.7 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.0 | 3.1 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.0 | 1.1 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.2 | GO:0001705 | ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712) |
| 0.0 | 0.6 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.0 | 2.0 | GO:0048675 | axon extension(GO:0048675) |
| 0.0 | 0.5 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 0.8 | GO:0048286 | lung alveolus development(GO:0048286) |
| 0.0 | 0.4 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.0 | 0.6 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
| 0.0 | 3.8 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 4.6 | GO:0051168 | nuclear export(GO:0051168) |
| 0.0 | 1.7 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.2 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.0 | 0.4 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.0 | 0.6 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 2.2 | GO:0043473 | pigmentation(GO:0043473) |
| 0.0 | 0.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.0 | 1.8 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.0 | 1.3 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.0 | 0.1 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 0.1 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.0 | 1.0 | GO:0070671 | interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349) |
| 0.0 | 0.7 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.2 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 0.4 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.0 | 3.0 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
| 0.0 | 2.4 | GO:0006457 | protein folding(GO:0006457) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 3.5 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.8 | 4.2 | GO:0042025 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 0.7 | 2.2 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 0.7 | 5.1 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.6 | 1.9 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.6 | 5.4 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.6 | 2.9 | GO:0033503 | HULC complex(GO:0033503) |
| 0.5 | 4.2 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.5 | 5.0 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.5 | 3.3 | GO:0031415 | NatA complex(GO:0031415) |
| 0.4 | 1.2 | GO:0033597 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 0.4 | 5.6 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.3 | 1.7 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.3 | 1.9 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.3 | 0.9 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 0.3 | 2.1 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.3 | 3.6 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.3 | 0.9 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.3 | 2.9 | GO:0042587 | glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357) |
| 0.3 | 3.5 | GO:0090543 | Flemming body(GO:0090543) |
| 0.2 | 0.7 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.2 | 1.7 | GO:0016589 | NURF complex(GO:0016589) |
| 0.2 | 3.2 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.2 | 3.0 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.2 | 4.4 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.2 | 3.5 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.2 | 3.0 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.2 | 1.3 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.2 | 1.3 | GO:0005818 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.2 | 2.1 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.2 | 2.4 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.2 | 1.0 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.2 | 3.4 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.2 | 0.8 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.2 | 1.6 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.2 | 2.6 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.2 | 1.4 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.2 | 0.9 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.2 | 1.2 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.2 | 13.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 5.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 0.7 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.1 | 1.2 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.1 | 2.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 10.4 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 1.8 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.1 | 2.6 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 4.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.1 | 1.9 | GO:0032059 | bleb(GO:0032059) |
| 0.1 | 1.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 2.4 | GO:0044453 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.1 | 2.1 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 3.8 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 2.5 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.1 | 12.4 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 6.8 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 1.1 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.1 | 1.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 0.9 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 1.4 | GO:0031332 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 3.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 0.9 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 7.1 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.1 | 1.4 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 1.6 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 0.4 | GO:0031673 | H zone(GO:0031673) |
| 0.1 | 1.0 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.1 | 0.7 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 2.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 2.4 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.1 | 0.9 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.1 | 2.7 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.1 | 1.5 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 0.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 2.0 | GO:0034385 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.1 | 3.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 2.6 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.1 | 0.5 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 1.3 | GO:1990752 | microtubule end(GO:1990752) |
| 0.0 | 0.4 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 0.5 | GO:0070449 | elongin complex(GO:0070449) |
| 0.0 | 0.7 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 0.6 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 0.0 | 1.4 | GO:0035267 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.0 | 2.2 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 3.2 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 2.2 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 6.6 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 1.4 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 2.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.8 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.4 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 1.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 2.0 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 8.8 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 5.7 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 0.6 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.0 | 0.3 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 1.7 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.7 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
| 0.0 | 0.1 | GO:0098845 | postsynaptic recycling endosome(GO:0098837) postsynaptic endosome(GO:0098845) |
| 0.0 | 1.4 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 6.2 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 1.0 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 0.4 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 2.0 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 5.1 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 2.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.7 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.0 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 2.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 1.0 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 1.0 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 1.0 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 1.3 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 2.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 1.7 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.0 | 1.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.1 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 0.1 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.0 | 3.6 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 0.7 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.8 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 3.9 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.4 | GO:0001772 | immunological synapse(GO:0001772) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 7.0 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 1.3 | 4.0 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 1.2 | 3.7 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 1.2 | 3.6 | GO:0070052 | collagen V binding(GO:0070052) |
| 1.2 | 3.6 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.9 | 5.5 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.8 | 2.5 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.8 | 2.4 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 0.8 | 2.4 | GO:0034416 | bisphosphoglycerate phosphatase activity(GO:0034416) |
| 0.7 | 2.1 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.7 | 3.5 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.7 | 2.0 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
| 0.6 | 2.4 | GO:0042282 | hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282) |
| 0.6 | 4.2 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 0.6 | 2.9 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.6 | 4.0 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.5 | 5.1 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.5 | 1.9 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.5 | 2.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.4 | 6.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.4 | 1.3 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.4 | 4.5 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.4 | 1.2 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.4 | 2.3 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.4 | 2.6 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.4 | 5.2 | GO:0046790 | virion binding(GO:0046790) |
| 0.3 | 1.7 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.3 | 1.0 | GO:0031403 | lithium ion binding(GO:0031403) |
| 0.3 | 1.9 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.3 | 0.9 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 0.3 | 0.9 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
| 0.3 | 1.2 | GO:0047676 | arachidonate-CoA ligase activity(GO:0047676) |
| 0.3 | 1.6 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.3 | 1.3 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.3 | 11.9 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 2.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.2 | 2.7 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.2 | 1.4 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) |
| 0.2 | 2.0 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.2 | 6.6 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.2 | 3.0 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.2 | 6.1 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.2 | 4.1 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.2 | 8.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.2 | 15.3 | GO:0019003 | GDP binding(GO:0019003) |
| 0.2 | 0.6 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.2 | 6.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.2 | 2.1 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 5.5 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 1.0 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 5.3 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.1 | 4.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 4.0 | GO:0071949 | FAD binding(GO:0071949) |
| 0.1 | 2.2 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.1 | 1.3 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 3.7 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 3.0 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 7.0 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 0.4 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) |
| 0.1 | 1.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 3.2 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 0.4 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.1 | 0.9 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.1 | 0.4 | GO:0050473 | arachidonate 15-lipoxygenase activity(GO:0050473) |
| 0.1 | 2.0 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 1.9 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 1.8 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 0.8 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.1 | 2.1 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.1 | 0.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.9 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.1 | 0.9 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.1 | 1.2 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.1 | 0.9 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.1 | 3.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.2 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.1 | 0.9 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.1 | 3.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 1.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 5.8 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.1 | 0.6 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.1 | 1.4 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.1 | 1.4 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.1 | 0.5 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.1 | 0.6 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.1 | 0.9 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 1.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.1 | 2.6 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 0.8 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 2.1 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.1 | 1.2 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 4.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 1.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 1.4 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.1 | 1.7 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 0.9 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 2.4 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 23.7 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 1.1 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 3.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.6 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 0.4 | GO:0004996 | thyroid-stimulating hormone receptor activity(GO:0004996) |
| 0.0 | 1.0 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 1.5 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 1.2 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.1 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.0 | 0.3 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 2.8 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 1.0 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.9 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 1.7 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.1 | GO:0015403 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.0 | 0.2 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.0 | 0.5 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.2 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.0 | 1.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 2.9 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.6 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 1.7 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.0 | 2.1 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.4 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.0 | 0.3 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.0 | 1.0 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 3.7 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 2.3 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.7 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 0.8 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.4 | GO:0046961 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.7 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.7 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 3.7 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.8 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 1.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.5 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 1.4 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.3 | GO:0000146 | microfilament motor activity(GO:0000146) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.0 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.2 | 1.7 | PID EPO PATHWAY | EPO signaling pathway |
| 0.2 | 5.5 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 5.9 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 5.7 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 8.7 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 8.1 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 1.7 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 5.0 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 2.1 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 6.8 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 5.1 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 2.7 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 0.7 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.1 | 3.2 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 3.0 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 1.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 3.4 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 2.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.1 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.1 | 2.2 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 4.1 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 0.8 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 4.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 2.5 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 3.3 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 2.0 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 2.3 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 2.7 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.4 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 1.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 4.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 3.9 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 2.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 1.5 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.6 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.9 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 3.2 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.2 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.8 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 0.3 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.5 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.8 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 1.0 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.5 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.4 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.6 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.3 | 4.7 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.3 | 6.1 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.3 | 5.1 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.3 | 2.9 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.3 | 7.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 6.2 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.2 | 6.1 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.2 | 6.2 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.2 | 4.8 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.2 | 3.6 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.2 | 3.7 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 4.0 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.1 | 6.1 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 1.7 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.1 | 4.9 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 2.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 3.5 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 5.6 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 1.4 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 9.4 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 2.2 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 4.1 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 5.9 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 2.9 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.5 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 3.8 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.1 | 3.4 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.1 | 1.2 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 1.1 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.1 | 4.9 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.1 | 1.0 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 3.3 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |
| 0.0 | 1.6 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 3.2 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.9 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 6.7 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 7.3 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.0 | 0.9 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 3.0 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 1.7 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.6 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.0 | 0.9 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.7 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.9 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 2.4 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.0 | 3.0 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 3.1 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 0.3 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 0.2 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.0 | 0.8 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 2.6 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 1.6 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.4 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 1.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.4 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |