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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UAGUGUU

Z-value: 1.25

Motif logo

miRNA associated with seed UAGUGUU

NamemiRBASE accession

Activity profile of UAGUGUU motif

Sorted Z-values of UAGUGUU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UAGUGUU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_183023409 25.50 ENST00000258341.5
laminin subunit gamma 1
chr1_-_225653045 22.55 ENST00000366843.6
ENST00000366844.7
ENAH actin regulator
chr3_+_172040554 22.33 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr20_+_17570046 22.18 ENST00000246069.12
ENST00000474024.5
destrin, actin depolymerizing factor
chr22_-_35840218 19.32 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr2_-_208255055 19.32 ENST00000345146.7
isocitrate dehydrogenase (NADP(+)) 1
chr5_+_102755269 18.42 ENST00000304400.12
ENST00000455264.7
ENST00000684529.1
ENST00000438793.8
ENST00000682882.1
ENST00000682972.1
ENST00000348126.7
ENST00000512073.1
peptidylglycine alpha-amidating monooxygenase
chr19_-_48391505 18.22 ENST00000600980.1
ENST00000330720.7
KDEL endoplasmic reticulum protein retention receptor 1
chr4_+_38867789 17.19 ENST00000358869.5
family with sequence similarity 114 member A1
chr14_+_61695777 16.74 ENST00000323441.10
hypoxia inducible factor 1 subunit alpha
chr3_+_172750682 15.91 ENST00000232458.9
ENST00000540509.5
epithelial cell transforming 2
chr2_-_183038405 15.22 ENST00000361354.9
NCK associated protein 1
chr13_+_75549734 14.81 ENST00000563635.5
ENST00000377595.8
novel transcript
ubiquitin C-terminal hydrolase L3
chr6_-_30744537 14.40 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr1_-_94927079 13.91 ENST00000370206.9
ENST00000394202.8
calponin 3
chr17_-_64662290 13.79 ENST00000262435.14
SMAD specific E3 ubiquitin protein ligase 2
chr9_+_111661588 13.20 ENST00000374293.5
G protein subunit gamma 10
chr3_+_41199494 13.07 ENST00000644138.1
ENST00000645276.1
ENST00000642426.1
ENST00000349496.11
ENST00000646116.1
ENST00000644873.1
ENST00000644867.1
ENST00000646725.1
ENST00000645493.1
ENST00000646369.1
ENST00000647413.1
ENST00000643977.1
catenin beta 1
chr5_+_83471736 13.04 ENST00000265077.8
versican
chr2_-_86563382 13.01 ENST00000263856.9
charged multivesicular body protein 3
chr9_+_107283256 12.94 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr12_+_101877571 12.93 ENST00000258534.13
DNA damage regulated autophagy modulator 1
chr1_-_67833448 12.40 ENST00000370982.4
G protein subunit gamma 12
chr11_+_57753243 12.26 ENST00000524630.5
ENST00000529919.5
ENST00000533189.1
catenin delta 1
chr12_-_6342066 12.19 ENST00000162749.7
ENST00000440083.6
TNF receptor superfamily member 1A
chr3_-_57597325 11.37 ENST00000496292.5
ENST00000489843.1
ENST00000303436.11
ADP ribosylation factor 4
chr3_+_100709473 11.35 ENST00000240851.9
ENST00000675243.1
ENST00000676111.1
ENST00000476228.5
ENST00000463568.6
ENST00000676395.1
trafficking from ER to golgi regulator
chr1_+_7771263 11.09 ENST00000054666.11
vesicle associated membrane protein 3
chr1_-_179877790 11.04 ENST00000495650.1
ENST00000367612.7
ENST00000482587.5
ENST00000609928.6
torsin 1A interacting protein 2
chr21_-_26170654 10.93 ENST00000439274.6
ENST00000358918.7
ENST00000354192.7
ENST00000348990.9
ENST00000346798.8
ENST00000357903.7
amyloid beta precursor protein
chr11_+_69641146 10.69 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr3_-_123884290 10.67 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
myosin light chain kinase
chr9_+_111631354 10.54 ENST00000374294.3
DNAJC25-GNG10 readthrough
chr2_-_39437264 10.03 ENST00000263881.8
ENST00000341681.9
mitogen-activated protein kinase kinase kinase kinase 3
chr8_+_125430333 9.89 ENST00000311922.4
tribbles pseudokinase 1
chr1_-_211579064 9.69 ENST00000367001.5
solute carrier family 30 member 1
chr22_+_32801697 9.48 ENST00000266085.7
TIMP metallopeptidase inhibitor 3
chr2_-_173965356 9.17 ENST00000310015.12
Sp3 transcription factor
chr6_-_81752671 8.36 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr2_-_157874976 8.24 ENST00000682025.1
ENST00000683487.1
ENST00000682300.1
ENST00000683441.1
ENST00000684595.1
ENST00000683426.1
ENST00000683820.1
ENST00000263640.7
activin A receptor type 1
chr17_+_59619885 8.20 ENST00000269122.8
ENST00000580081.1
ENST00000579456.5
clathrin heavy chain
chr11_-_65900413 8.16 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr8_+_63168597 7.97 ENST00000539294.6
ENST00000621957.4
ENST00000517371.5
ENST00000621413.4
ENST00000612880.4
YTH N6-methyladenosine RNA binding protein 3
chr5_+_179698906 7.71 ENST00000452673.6
ENST00000680614.1
ENST00000680812.1
ENST00000681265.1
ENST00000680894.1
ENST00000681894.1
ENST00000679642.1
ENST00000680827.1
ENST00000680984.1
ENST00000680042.1
ENST00000681476.1
ENST00000681072.1
ENST00000247461.9
ENST00000502673.6
ENST00000513246.6
ENST00000680618.1
ENST00000680092.1
ENST00000506654.6
calnexin
chr9_-_14314067 7.69 ENST00000397575.7
nuclear factor I B
chr2_+_46542474 7.69 ENST00000238738.9
ras homolog family member Q
chr13_+_99501464 7.65 ENST00000376387.5
transmembrane 9 superfamily member 2
chr3_-_33440343 7.61 ENST00000283629.8
upstream binding protein 1
chr4_+_41935423 7.51 ENST00000504986.6
transmembrane protein 33
chr21_-_41926680 7.31 ENST00000329623.11
C2 calcium dependent domain containing 2
chr7_-_6484057 7.28 ENST00000490996.1
ENST00000258739.9
ENST00000436575.5
KDEL endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase beta
chr10_+_86756580 7.26 ENST00000372037.8
bone morphogenetic protein receptor type 1A
chr10_+_61901678 7.23 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr10_+_73998104 7.20 ENST00000372755.7
ENST00000211998.10
vinculin
chr1_+_24745396 7.16 ENST00000374379.9
chloride intracellular channel 4
chr15_+_100879822 7.13 ENST00000329841.10
ENST00000557963.1
ENST00000346623.6
aldehyde dehydrogenase 1 family member A3
chr2_+_181891697 7.08 ENST00000431877.7
ITPR interacting domain containing 2
chr5_+_122775062 6.92 ENST00000379516.7
ENST00000505934.5
ENST00000514949.1
sorting nexin 2
chr21_+_33403391 6.82 ENST00000290219.11
ENST00000381995.5
interferon gamma receptor 2
chr2_-_241272812 6.78 ENST00000427007.5
ENST00000458564.5
ENST00000452065.5
ENST00000427183.6
ENST00000426343.5
ENST00000422080.5
ENST00000449504.5
ENST00000449864.5
ENST00000391975.5
high density lipoprotein binding protein
chr17_-_1400168 6.69 ENST00000573026.1
ENST00000575977.1
ENST00000571732.5
ENST00000264335.13
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
chr2_-_61538313 6.67 ENST00000677803.1
ENST00000677239.1
ENST00000401558.7
exportin 1
chr3_-_160565560 6.57 ENST00000334256.9
ENST00000676866.1
ENST00000469804.1
karyopherin subunit alpha 4
chr3_-_177196451 6.57 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1X receptor 1
chr6_-_24719146 6.41 ENST00000378119.9
chromosome 6 open reading frame 62
chr16_+_3020359 6.36 ENST00000341627.5
ENST00000326577.9
ENST00000575124.1
ENST00000575836.1
TNF receptor superfamily member 12A
chrX_-_20266834 6.27 ENST00000379565.9
ribosomal protein S6 kinase A3
chr8_-_143939543 6.26 ENST00000345136.8
plectin
chr3_-_72446623 6.18 ENST00000477973.4
RING1 and YY1 binding protein
chr19_+_54190268 6.10 ENST00000429671.7
ENST00000302937.8
ENST00000667261.1
tRNA splicing endonuclease subunit 34
chr17_+_28335718 6.06 ENST00000226225.7
TNF alpha induced protein 1
chr11_+_34621065 6.05 ENST00000257831.8
ETS homologous factor
chr15_+_65869535 6.02 ENST00000569896.1
RAB11A, member RAS oncogene family
chr1_+_93448155 5.84 ENST00000370253.6
formin binding protein 1 like
chr1_+_86704564 5.83 ENST00000616170.4
ENST00000535010.5
ENST00000370558.8
SH3 domain containing GRB2 like, endophilin B1
chr9_+_36190856 5.74 ENST00000433436.6
ENST00000538225.5
ENST00000540080.5
clathrin light chain A
chr1_+_215567279 5.64 ENST00000259154.9
potassium channel tetramerization domain containing 3
chr2_-_20051610 5.34 ENST00000175091.5
lysosomal protein transmembrane 4 alpha
chrX_+_147911943 5.22 ENST00000621453.4
ENST00000218200.12
ENST00000370471.7
ENST00000440235.6
ENST00000370477.5
ENST00000621987.4
FMRP translational regulator 1
chr17_-_82648428 5.19 ENST00000392325.9
WD repeat domain 45B
chr17_-_21214122 5.15 ENST00000317635.6
transmembrane protein 11
chr3_+_180912656 5.10 ENST00000357559.9
ENST00000491062.5
ENST00000468861.5
ENST00000445140.6
ENST00000484958.5
FMR1 autosomal homolog 1
chr6_+_25279359 5.04 ENST00000329474.7
capping protein regulator and myosin 1 linker 1
chr17_+_1829981 5.00 ENST00000254719.10
replication protein A1
chr10_-_32056376 4.93 ENST00000302418.5
kinesin family member 5B
chr17_-_1456149 4.85 ENST00000574295.1
ENST00000398970.5
ENST00000300574.3
CRK proto-oncogene, adaptor protein
chr15_+_90388234 4.85 ENST00000268182.10
ENST00000560738.1
ENST00000560418.1
IQ motif containing GTPase activating protein 1
chr16_-_73048104 4.83 ENST00000268489.10
zinc finger homeobox 3
chr13_-_76886397 4.75 ENST00000377474.4
potassium channel tetramerization domain containing 12
chr5_+_80407994 4.71 ENST00000338008.9
ENST00000510158.5
zinc finger FYVE-type containing 16
chr16_-_85688912 4.68 ENST00000253462.8
GINS complex subunit 2
chr1_+_78004930 4.64 ENST00000370763.6
DnaJ heat shock protein family (Hsp40) member B4
chr12_-_46372763 4.56 ENST00000256689.10
solute carrier family 38 member 2
chr10_+_5684828 4.44 ENST00000328090.9
ENST00000496681.5
transcription activation suppressor family member 2
chr3_+_33798557 4.40 ENST00000457054.6
ENST00000413073.1
ENST00000307296.8
programmed cell death 6 interacting protein
chr16_+_83807958 4.38 ENST00000433866.7
ENST00000570259.1
heat shock factor binding protein 1
chr7_+_130070518 4.28 ENST00000335420.10
ENST00000463413.1
kelch domain containing 10
chr5_+_179732811 4.14 ENST00000292599.4
mastermind like transcriptional coactivator 1
chr10_+_132537778 4.13 ENST00000368594.8
inositol polyphosphate-5-phosphatase A
chr2_-_65432591 4.09 ENST00000356388.9
sprouty related EVH1 domain containing 2
chr1_-_56579555 4.01 ENST00000371250.4
phospholipid phosphatase 3
chr16_-_66751591 3.96 ENST00000440564.6
ENST00000443351.6
ENST00000566150.5
ENST00000258198.7
dynein cytoplasmic 1 light intermediate chain 2
chr19_-_4400418 3.87 ENST00000598564.5
ENST00000417295.6
ENST00000269886.7
SH3 domain containing GRB2 like 1, endophilin A2
chr6_-_16761447 3.84 ENST00000244769.8
ENST00000436367.6
ataxin 1
chr1_+_200739542 3.83 ENST00000358823.6
calmodulin regulated spectrin associated protein family member 2
chr12_+_111405861 3.74 ENST00000341259.7
SH2B adaptor protein 3
chr8_-_61714498 3.67 ENST00000519234.5
ENST00000379449.10
ENST00000518068.5
ENST00000517856.5
ENST00000379454.9
ENST00000356457.9
aspartate beta-hydroxylase
chr9_-_121201836 3.65 ENST00000373840.9
RAB14, member RAS oncogene family
chr13_-_110307131 3.62 ENST00000543140.6
ENST00000375820.10
collagen type IV alpha 1 chain
chr7_-_23470469 3.60 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chr17_+_7572818 3.54 ENST00000293831.13
ENST00000582169.5
ENST00000578754.5
ENST00000578495.5
ENST00000585024.5
ENST00000583802.5
ENST00000577269.5
ENST00000584784.5
ENST00000582746.5
ENST00000581621.1
eukaryotic translation initiation factor 4A1
novel transcript
chr1_+_32013848 3.52 ENST00000327300.12
ENST00000492989.1
KH RNA binding domain containing, signal transduction associated 1
chrX_-_20141810 3.41 ENST00000379593.1
ENST00000379607.10
eukaryotic translation initiation factor 1A X-linked
chr3_+_105366877 3.37 ENST00000306107.9
activated leukocyte cell adhesion molecule
chr4_+_98995709 3.35 ENST00000296411.11
ENST00000625963.1
methionyl aminopeptidase 1
chr3_-_98901656 3.23 ENST00000326840.11
discoidin, CUB and LCCL domain containing 2
chr8_+_60516947 3.17 ENST00000262646.12
RAB2A, member RAS oncogene family
chr1_-_31065671 3.10 ENST00000440538.6
ENST00000424085.6
ENST00000257075.9
ENST00000373747.7
ENST00000426105.7
ENST00000525843.5
ENST00000373742.6
pumilio RNA binding family member 1
chr3_-_45995807 3.06 ENST00000535325.5
ENST00000296137.7
FYVE and coiled-coil domain autophagy adaptor 1
chr5_-_115625972 2.98 ENST00000333314.3
ENST00000456936.4
TMED7-TICAM2 readthrough
transmembrane p24 trafficking protein 7
chr3_-_50359480 2.87 ENST00000266025.4
transmembrane protein 115
chr17_-_62065248 2.86 ENST00000397786.7
mediator complex subunit 13
chr3_+_150408314 2.82 ENST00000361875.7
TSC22 domain family member 2
chr6_-_113971120 2.78 ENST00000520895.5
ENST00000521163.5
ENST00000524334.1
ENST00000519065.6
ENST00000368632.6
histone deacetylase 2
chr12_-_54419259 2.76 ENST00000293379.9
integrin subunit alpha 5
chr2_+_46698909 2.72 ENST00000650611.1
ENST00000306503.5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr1_-_243850070 2.71 ENST00000366539.6
ENST00000672578.1
AKT serine/threonine kinase 3
chr10_-_59906509 2.68 ENST00000263102.7
coiled-coil domain containing 6
chr11_+_118606428 2.67 ENST00000361417.6
pleckstrin homology like domain family B member 1
chr11_-_65614195 2.66 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr14_+_54567612 2.59 ENST00000251091.9
ENST00000392067.7
ENST00000631086.2
sterile alpha motif domain containing 4A
chr9_-_83980578 2.57 ENST00000376281.8
heterogeneous nuclear ribonucleoprotein K
chr15_+_90265634 2.54 ENST00000379095.5
neugrin, neurite outgrowth associated
chr1_+_35268663 2.53 ENST00000314607.11
zinc finger MYM-type containing 4
chr16_+_56932134 2.51 ENST00000439977.7
ENST00000300302.9
ENST00000344114.8
ENST00000379792.6
homocysteine inducible ER protein with ubiquitin like domain 1
chr3_+_129249594 2.48 ENST00000314797.10
COPI coat complex subunit gamma 1
chr14_-_63543328 2.47 ENST00000337537.8
protein phosphatase 2 regulatory subunit B'epsilon
chr1_-_231422261 2.41 ENST00000366641.4
egl-9 family hypoxia inducible factor 1
chr17_+_40219276 2.40 ENST00000583268.1
ENST00000323571.9
WAS/WASL interacting protein family member 2
chr5_-_180353317 2.39 ENST00000253778.13
glutamine-fructose-6-phosphate transaminase 2
chr2_+_190649062 2.39 ENST00000409581.5
ENST00000337386.10
NGFI-A binding protein 1
chrX_-_74614612 2.38 ENST00000349225.2
ENST00000332687.11
ring finger protein, LIM domain interacting
chr1_-_202808406 2.33 ENST00000650569.1
ENST00000367265.9
ENST00000649770.1
lysine demethylase 5B
chr5_-_143403611 2.32 ENST00000394464.7
ENST00000231509.7
nuclear receptor subfamily 3 group C member 1
chr6_-_52577012 2.25 ENST00000182527.4
translocation associated membrane protein 2
chr1_+_201829132 2.25 ENST00000361565.9
importin 9
chr15_+_58987652 2.23 ENST00000348370.9
ENST00000559160.1
ring finger protein 111
chr1_-_243255170 2.22 ENST00000366542.6
centrosomal protein 170
chrX_-_41922992 2.19 ENST00000646120.2
ENST00000421587.8
ENST00000644770.1
ENST00000645566.1
ENST00000378166.9
ENST00000378158.6
ENST00000644219.1
ENST00000442742.7
ENST00000644347.1
calcium/calmodulin dependent serine protein kinase
chr10_-_97687191 2.17 ENST00000370626.4
arginine vasopressin induced 1
chr9_-_16870662 2.07 ENST00000380672.9
basonuclin 2
chr10_-_100185993 2.04 ENST00000421367.7
ENST00000370408.2
ENST00000407654.7
ER lipid raft associated 1
chr12_-_25250879 1.98 ENST00000256078.10
ENST00000311936.8
ENST00000556131.1
ENST00000557334.5
KRAS proto-oncogene, GTPase
chr6_-_116060859 1.98 ENST00000606080.2
fyn related Src family tyrosine kinase
chr16_-_4116403 1.80 ENST00000294016.8
adenylate cyclase 9
chr14_+_57268963 1.78 ENST00000261558.8
adaptor related protein complex 5 subunit mu 1
chr7_-_13989658 1.76 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr15_+_84980440 1.76 ENST00000310298.8
ENST00000557957.5
phosphodiesterase 8A
chr14_+_102592611 1.74 ENST00000262241.7
REST corepressor 1
chr1_+_65147514 1.74 ENST00000545314.5
adenylate kinase 4
chr20_-_17682234 1.69 ENST00000377813.6
ENST00000377807.6
ENST00000360807.8
ENST00000398782.2
ribosome binding protein 1
chr12_+_120446418 1.66 ENST00000551765.6
ENST00000229384.5
glutamyl-tRNA amidotransferase subunit C
chr5_-_16936231 1.63 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
myosin X
chr7_-_88220025 1.56 ENST00000419179.5
ENST00000265729.7
sorcin
chr4_-_138242325 1.53 ENST00000280612.9
solute carrier family 7 member 11
chr2_+_147845020 1.50 ENST00000241416.12
activin A receptor type 2A
chr9_+_130579556 1.44 ENST00000319725.10
far upstream element binding protein 3
chr1_+_88684222 1.43 ENST00000316005.11
ENST00000370521.8
protein kinase N2
chr1_-_92792396 1.42 ENST00000370331.5
ENST00000540033.2
ecotropic viral integration site 5
chr12_+_120438107 1.41 ENST00000229379.3
ENST00000551806.1
cytochrome c oxidase subunit 6A1
novel protein
chr12_-_89656051 1.38 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr12_-_24949026 1.35 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
branched chain amino acid transaminase 1
chr3_-_15859771 1.35 ENST00000399451.6
ankyrin repeat domain 28
chr2_+_105744876 1.33 ENST00000233154.9
ENST00000451463.6
NCK adaptor protein 2
chr12_-_105236074 1.26 ENST00000551662.5
ENST00000553097.5
ENST00000258530.8
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
chr2_+_207529892 1.25 ENST00000432329.6
ENST00000445803.5
cAMP responsive element binding protein 1
chr1_+_186828941 1.16 ENST00000367466.4
phospholipase A2 group IVA
chr1_-_37859583 1.12 ENST00000373036.5
metal regulatory transcription factor 1
chr2_+_66435558 1.04 ENST00000488550.5
Meis homeobox 1
chr10_-_102502669 0.97 ENST00000487599.1
actin related protein 1A
chr7_-_99144053 0.95 ENST00000361125.1
ENST00000361368.7
SMAD specific E3 ubiquitin protein ligase 1
chr19_-_55370455 0.93 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chr4_-_184826030 0.93 ENST00000507295.5
ENST00000504900.5
ENST00000454703.6
acyl-CoA synthetase long chain family member 1
chr11_-_77820706 0.88 ENST00000440064.2
ENST00000528095.5
ENST00000308488.11
remodeling and spacing factor 1
chr6_+_17600273 0.87 ENST00000259963.4
family with sequence similarity 8 member A1
chr5_-_157059109 0.82 ENST00000523175.6
ENST00000522693.5
hepatitis A virus cellular receptor 1
chr12_+_48122574 0.80 ENST00000549022.5
ENST00000547587.5
ENST00000312352.11
phosphofructokinase, muscle
chr12_+_49367440 0.79 ENST00000552918.6
ENST00000553127.5
ENST00000321898.10
spermatogenesis associated serine rich 2
chr9_-_122828539 0.79 ENST00000259467.9
phosducin like
chr4_-_41214602 0.75 ENST00000508676.5
ENST00000506352.5
ENST00000295974.12
amyloid beta precursor protein binding family B member 2
chr2_-_112784486 0.74 ENST00000263339.4
interleukin 1 alpha
chr12_+_67269328 0.73 ENST00000545606.6
cullin associated and neddylation dissociated 1
chr6_-_33298909 0.70 ENST00000497454.6
ral guanine nucleotide dissociation stimulator like 2
chr22_+_31212207 0.68 ENST00000406516.5
ENST00000331728.9
LIM domain kinase 2
chr16_+_85613252 0.68 ENST00000253458.12
ENST00000393243.5
Gse1 coiled-coil protein
chr15_+_90529862 0.64 ENST00000268184.11
ENST00000420329.6
CREB regulated transcription coactivator 3
chr17_+_81683963 0.63 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr16_+_22297375 0.61 ENST00000615879.4
ENST00000299853.10
ENST00000564209.5
ENST00000565358.5
ENST00000418581.6
ENST00000564883.5
ENST00000359210.8
ENST00000563024.5
RNA polymerase III subunit E
chr1_-_108963413 0.61 ENST00000676454.1
ENST00000675790.1
ENST00000674849.1
ENST00000675956.1
ENST00000369976.5
ENST00000675584.1
ENST00000302500.5
ENST00000356970.6
ENST00000676392.1
ENST00000676059.1
ENST00000675571.1
ENST00000675018.1
ENST00000674527.1
ENST00000369968.7
ENST00000369969.7
ENST00000675508.1
ENST00000675650.1
ENST00000369970.8
ENST00000675654.1
ENST00000357393.6
chloride channel CLIC like 1
AKNA domain containing 1
chr7_-_24980148 0.57 ENST00000313367.7
oxysterol binding protein like 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.3 GO:0006097 glyoxylate cycle(GO:0006097)
4.6 18.4 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
3.4 13.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
3.3 9.9 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
2.8 16.7 GO:0070101 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
2.8 19.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
2.7 8.2 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
2.6 13.1 GO:2000017 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) positive regulation of determination of dorsal identity(GO:2000017)
2.5 25.5 GO:0006621 protein retention in ER lumen(GO:0006621)
2.5 5.0 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
2.4 7.1 GO:0060166 olfactory pit development(GO:0060166)
2.4 9.5 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
2.2 6.7 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
2.2 22.2 GO:0030043 actin filament fragmentation(GO:0030043)
2.0 8.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
1.9 5.8 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
1.9 7.5 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.8 10.9 GO:0048669 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
1.8 7.3 GO:0048378 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
1.7 5.2 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
1.6 9.7 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
1.6 11.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
1.5 6.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.5 6.0 GO:0010796 regulation of multivesicular body size(GO:0010796)
1.5 28.2 GO:0070831 basement membrane assembly(GO:0070831)
1.5 4.4 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
1.4 13.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
1.4 13.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.4 2.8 GO:0061198 fungiform papilla formation(GO:0061198)
1.4 4.1 GO:0003162 atrioventricular node development(GO:0003162)
1.4 8.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.3 11.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
1.1 15.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.1 6.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.0 10.7 GO:0033327 Leydig cell differentiation(GO:0033327)
1.0 4.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.9 12.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.9 11.0 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.9 3.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.9 9.2 GO:0060136 enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.9 3.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.9 7.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.9 8.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.9 3.5 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.7 6.6 GO:0060613 fat pad development(GO:0060613)
0.7 7.7 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 2.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.7 6.1 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.7 2.0 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.6 2.6 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.6 13.9 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.6 6.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.6 2.4 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.6 2.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.6 7.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.6 1.7 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.5 8.2 GO:0009629 response to gravity(GO:0009629)
0.5 13.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.5 3.7 GO:0032328 alanine transport(GO:0032328)
0.5 7.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.5 6.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.5 12.3 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.5 27.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.5 6.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.5 4.7 GO:1902969 mitotic DNA replication(GO:1902969)
0.5 2.3 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.5 3.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.4 5.8 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.4 2.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 4.8 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.4 2.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4 10.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 17.9 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.4 7.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.4 9.9 GO:0061157 mRNA destabilization(GO:0061157)
0.4 6.8 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.3 3.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 0.9 GO:0034201 response to oleic acid(GO:0034201)
0.3 4.0 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.3 3.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.3 4.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.3 1.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 1.4 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3 2.4 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.3 6.6 GO:0019054 modulation by virus of host process(GO:0019054)
0.3 2.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.3 4.1 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.2 5.7 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.2 6.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 5.1 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 1.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 7.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.2 5.2 GO:0044804 nucleophagy(GO:0044804)
0.2 2.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 1.6 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 1.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 2.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.2 2.5 GO:0051683 establishment of Golgi localization(GO:0051683)
0.2 2.8 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 0.8 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 1.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 1.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 6.8 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2 3.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 3.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 0.9 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.7 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.1 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.1 3.4 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 5.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.9 GO:0016584 nucleosome positioning(GO:0016584)
0.1 3.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 2.1 GO:0043586 tongue development(GO:0043586)
0.1 4.0 GO:0051642 centrosome localization(GO:0051642)
0.1 4.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 2.4 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 1.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 5.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 13.3 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
0.1 0.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.7 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 4.6 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 1.8 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1 1.0 GO:0060044 megakaryocyte development(GO:0035855) negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 2.2 GO:0046710 GDP metabolic process(GO:0046710)
0.1 2.4 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 1.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 4.2 GO:0048207 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 4.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 7.2 GO:0001889 liver development(GO:0001889)
0.0 13.8 GO:0007411 axon guidance(GO:0007411)
0.0 0.1 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.0 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 9.3 GO:0010506 regulation of autophagy(GO:0010506)
0.0 3.3 GO:0019079 viral genome replication(GO:0019079)
0.0 3.6 GO:0017148 negative regulation of translation(GO:0017148)
0.0 1.1 GO:0046686 response to cadmium ion(GO:0046686)
0.0 8.6 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 2.7 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 4.1 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.3 GO:0006970 response to osmotic stress(GO:0006970)
0.0 2.0 GO:0051168 nuclear export(GO:0051168)
0.0 0.2 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 25.5 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
3.2 12.9 GO:0071942 XPC complex(GO:0071942)
3.2 15.9 GO:0097149 centralspindlin complex(GO:0097149)
2.2 13.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
2.1 8.2 GO:0048179 activin receptor complex(GO:0048179)
1.7 5.2 GO:1902737 dendritic filopodium(GO:1902737)
1.6 10.9 GO:1990812 growth cone filopodium(GO:1990812)
1.5 23.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
1.4 13.9 GO:0071439 clathrin complex(GO:0071439)
1.2 6.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.2 6.0 GO:0098837 postsynaptic recycling endosome(GO:0098837)
1.2 15.2 GO:0031209 SCAR complex(GO:0031209)
1.2 4.7 GO:0000811 GINS complex(GO:0000811)
1.0 13.0 GO:0000815 ESCRT III complex(GO:0000815)
1.0 6.9 GO:0030905 retromer, tubulation complex(GO:0030905)
1.0 3.8 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.9 12.3 GO:0005915 zonula adherens(GO:0005915)
0.9 2.8 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.7 5.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.6 1.7 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.5 15.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.5 7.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.5 36.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 4.9 GO:0035253 ciliary rootlet(GO:0035253)
0.5 7.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.5 9.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.5 4.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5 3.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.5 3.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.4 6.7 GO:0005642 annulate lamellae(GO:0005642)
0.4 4.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 7.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 7.2 GO:0005916 fascia adherens(GO:0005916)
0.4 2.5 GO:1990037 Lewy body core(GO:1990037)
0.3 19.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 1.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.3 16.7 GO:1904115 axon cytoplasm(GO:1904115)
0.3 6.3 GO:0030056 hemidesmosome(GO:0030056)
0.3 2.7 GO:0045180 basal cortex(GO:0045180)
0.3 5.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 1.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 1.6 GO:0044326 dendritic spine neck(GO:0044326)
0.2 2.9 GO:0017119 Golgi transport complex(GO:0017119)
0.2 26.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 0.6 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 24.8 GO:0030175 filopodium(GO:0030175)
0.2 12.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 5.8 GO:0000421 autophagosome membrane(GO:0000421)
0.2 14.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 3.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 19.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 5.2 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 3.8 GO:1990752 microtubule end(GO:1990752)
0.2 6.4 GO:0002102 podosome(GO:0002102)
0.2 6.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 6.7 GO:0005871 kinesin complex(GO:0005871)
0.2 1.0 GO:0002177 manchette(GO:0002177)
0.2 3.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 4.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 1.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 15.1 GO:0042734 presynaptic membrane(GO:0042734)
0.1 16.9 GO:0043204 perikaryon(GO:0043204)
0.1 20.9 GO:0043197 dendritic spine(GO:0043197)
0.1 7.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 7.2 GO:0005902 microvillus(GO:0005902)
0.1 3.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 12.2 GO:0005643 nuclear pore(GO:0005643)
0.1 13.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.1 4.6 GO:0031519 PcG protein complex(GO:0031519)
0.1 7.9 GO:0005884 actin filament(GO:0005884)
0.1 2.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.8 GO:0030315 T-tubule(GO:0030315)
0.1 20.6 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 4.6 GO:0042383 sarcolemma(GO:0042383)
0.0 1.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 6.4 GO:0001726 ruffle(GO:0001726)
0.0 3.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 5.0 GO:0016605 PML body(GO:0016605)
0.0 5.4 GO:0005938 cell cortex(GO:0005938)
0.0 9.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 3.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.9 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 25.5 GO:0005046 KDEL sequence binding(GO:0005046)
6.4 19.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
4.6 18.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
2.7 10.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.6 7.7 GO:0032427 GBD domain binding(GO:0032427)
2.0 12.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
1.7 6.8 GO:0004906 interferon-gamma receptor activity(GO:0004906)
1.6 14.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.5 6.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
1.5 9.1 GO:0034046 poly(G) binding(GO:0034046)
1.5 8.8 GO:0098821 BMP receptor activity(GO:0098821)
1.4 6.9 GO:1990460 leptin receptor binding(GO:1990460)
1.4 8.2 GO:0016361 activin receptor activity, type I(GO:0016361)
1.4 4.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.2 4.9 GO:0099609 microtubule lateral binding(GO:0099609)
1.2 3.7 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
1.1 12.4 GO:0042301 phosphate ion binding(GO:0042301)
1.1 10.9 GO:0051425 PTB domain binding(GO:0051425)
1.1 20.3 GO:0045294 alpha-catenin binding(GO:0045294)
1.0 6.7 GO:0050815 phosphoserine binding(GO:0050815)
0.9 4.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.7 8.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.7 13.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.7 4.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.7 8.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.7 2.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.6 9.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.6 2.4 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.6 7.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 4.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.6 2.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.6 1.7 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.5 9.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.5 3.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.5 5.1 GO:0002151 G-quadruplex RNA binding(GO:0002151) RNA strand annealing activity(GO:0033592)
0.5 10.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 13.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.5 22.6 GO:0050699 WW domain binding(GO:0050699)
0.5 2.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.5 2.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 6.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 15.7 GO:0001671 ATPase activator activity(GO:0001671)
0.4 9.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 5.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 38.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 10.7 GO:0070064 proline-rich region binding(GO:0070064)
0.4 9.7 GO:0031489 myosin V binding(GO:0031489)
0.4 5.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.4 3.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.4 6.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 1.7 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 16.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 7.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.3 11.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 11.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 7.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 4.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 36.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.3 1.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3 4.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 2.8 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.3 1.4 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 6.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 2.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 10.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 1.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.2 1.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 5.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 6.3 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.0 GO:0048185 activin binding(GO:0048185)
0.2 2.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 2.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 3.6 GO:0000339 RNA cap binding(GO:0000339)
0.2 0.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 10.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 7.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 6.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 3.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 38.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 4.1 GO:0042605 peptide antigen binding(GO:0042605)
0.1 2.0 GO:0030275 LRR domain binding(GO:0030275)
0.1 4.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 3.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 20.8 GO:0051015 actin filament binding(GO:0051015)
0.1 3.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 8.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 28.8 GO:0045296 cadherin binding(GO:0045296)
0.1 2.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 2.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 3.4 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 4.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 3.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 2.9 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 9.4 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 25.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.0 83.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.7 19.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.7 17.7 PID ARF 3PATHWAY Arf1 pathway
0.5 26.7 PID BMP PATHWAY BMP receptor signaling
0.4 8.0 PID ALK2 PATHWAY ALK2 signaling events
0.4 18.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.4 13.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 14.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 6.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 12.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 15.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 6.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 12.1 PID AURORA B PATHWAY Aurora B signaling
0.2 15.9 PID PLK1 PATHWAY PLK1 signaling events
0.2 12.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 10.0 PID TNF PATHWAY TNF receptor signaling pathway
0.2 2.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 8.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 10.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 2.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 7.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 6.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 3.7 PID EPO PATHWAY EPO signaling pathway
0.1 3.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 5.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 2.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 6.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 6.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 4.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 4.6 PID E2F PATHWAY E2F transcription factor network
0.1 2.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 6.2 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 9.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 25.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.9 19.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.7 13.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.7 28.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.6 13.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.6 19.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.6 25.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.6 10.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.5 17.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.5 9.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.5 14.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.5 22.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.5 7.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.5 13.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 12.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 17.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 1.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 4.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 6.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 6.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 6.8 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.3 22.6 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.2 8.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 6.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 2.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 3.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 32.1 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.2 4.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 6.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 7.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 4.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 2.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 3.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 2.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 5.9 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 0.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 7.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 10.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 2.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 7.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 3.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 3.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 3.6 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 2.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events