GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Name	miRBASE accession
hsa-miR-142-3p.2 Links miRBase

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Promoter	Score	Transcript	Gene	Gene Info
chr1_+_183023409 Show fit	25.50	ENST00000258341.5	LAMC1 Links Ensembl NCBI GeneCards UniProt Show fit	laminin subunit gamma 1
chr1_-_225653045 Show fit	22.55	ENST00000366843.6 ENST00000366844.7	ENAH Links Ensembl NCBI GeneCards UniProt Show fit	ENAH actin regulator
chr3_+_172040554 Show fit	22.33	ENST00000336824.8 ENST00000423424.5	FNDC3B Links Ensembl NCBI GeneCards UniProt Show fit	fibronectin type III domain containing 3B
chr20_+_17570046 Show fit	22.18	ENST00000246069.12 ENST00000474024.5	DSTN Links Ensembl NCBI GeneCards UniProt Show fit	destrin, actin depolymerizing factor
chr22_-_35840218 Show fit	19.32	ENST00000414461.6 ENST00000416721.6 ENST00000449924.6 ENST00000262829.11 ENST00000397305.3	RBFOX2 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 2
chr2_-_208255055 Show fit	19.32	ENST00000345146.7	IDH1 Links Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NADP(+)) 1
chr5_+_102755269 Show fit	18.42	ENST00000304400.12 ENST00000455264.7 ENST00000684529.1 ENST00000438793.8 ENST00000682882.1 ENST00000682972.1 ENST00000348126.7 ENST00000512073.1	PAM Links Ensembl NCBI GeneCards UniProt Show fit	peptidylglycine alpha-amidating monooxygenase
chr19_-_48391505 Show fit	18.22	ENST00000600980.1 ENST00000330720.7	KDELR1 Links Ensembl NCBI GeneCards UniProt Show fit	KDEL endoplasmic reticulum protein retention receptor 1
chr4_+_38867789 Show fit	17.19	ENST00000358869.5	FAM114A1 Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 114 member A1
chr14_+_61695777 Show fit	16.74	ENST00000323441.10	HIF1A Links Ensembl NCBI GeneCards UniProt Show fit	hypoxia inducible factor 1 subunit alpha
chr3_+_172750682 Show fit	15.91	ENST00000232458.9 ENST00000540509.5	ECT2 Links Ensembl NCBI GeneCards UniProt Show fit	epithelial cell transforming 2
chr2_-_183038405 Show fit	15.22	ENST00000361354.9	NCKAP1 Links Ensembl NCBI GeneCards UniProt Show fit	NCK associated protein 1
chr13_+_75549734 Show fit	14.81	ENST00000563635.5 ENST00000377595.8	ENSG00000261553.5 Links Ensembl NCBI GeneCards UniProt Show fit UCHL3 Links Ensembl NCBI GeneCards UniProt Show fit	novel transcript ubiquitin C-terminal hydrolase L3
chr6_-_30744537 Show fit	14.40	ENST00000259874.6 ENST00000376377.2	IER3 Links Ensembl NCBI GeneCards UniProt Show fit	immediate early response 3
chr1_-_94927079 Show fit	13.91	ENST00000370206.9 ENST00000394202.8	CNN3 Links Ensembl NCBI GeneCards UniProt Show fit	calponin 3
chr17_-_64662290 Show fit	13.79	ENST00000262435.14	SMURF2 Links Ensembl NCBI GeneCards UniProt Show fit	SMAD specific E3 ubiquitin protein ligase 2
chr9_+_111661588 Show fit	13.20	ENST00000374293.5	GNG10 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit gamma 10
chr3_+_41199494 Show fit	13.07	ENST00000644138.1 ENST00000645276.1 ENST00000642426.1 ENST00000349496.11 ENST00000646116.1 ENST00000644873.1 ENST00000644867.1 ENST00000646725.1 ENST00000645493.1 ENST00000646369.1 ENST00000647413.1 ENST00000643977.1	CTNNB1 Links Ensembl NCBI GeneCards UniProt Show fit	catenin beta 1
chr5_+_83471736 Show fit	13.04	ENST00000265077.8	VCAN Links Ensembl NCBI GeneCards UniProt Show fit	versican
chr2_-_86563382 Show fit	13.01	ENST00000263856.9	CHMP3 Links Ensembl NCBI GeneCards UniProt Show fit	charged multivesicular body protein 3
chr9_+_107283256 Show fit	12.94	ENST00000358015.8	RAD23B Links Ensembl NCBI GeneCards UniProt Show fit	RAD23 homolog B, nucleotide excision repair protein
chr12_+_101877571 Show fit	12.93	ENST00000258534.13	DRAM1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA damage regulated autophagy modulator 1
chr1_-_67833448 Show fit	12.40	ENST00000370982.4	GNG12 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit gamma 12
chr11_+_57753243 Show fit	12.26	ENST00000524630.5 ENST00000529919.5 ENST00000533189.1	CTNND1 Links Ensembl NCBI GeneCards UniProt Show fit	catenin delta 1
chr12_-_6342066 Show fit	12.19	ENST00000162749.7 ENST00000440083.6	TNFRSF1A Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 1A
chr3_-_57597325 Show fit	11.37	ENST00000496292.5 ENST00000489843.1 ENST00000303436.11	ARF4 Links Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 4
chr3_+_100709473 Show fit	11.35	ENST00000240851.9 ENST00000675243.1 ENST00000676111.1 ENST00000476228.5 ENST00000463568.6 ENST00000676395.1	TFG Links Ensembl NCBI GeneCards UniProt Show fit	trafficking from ER to golgi regulator
chr1_+_7771263 Show fit	11.09	ENST00000054666.11	VAMP3 Links Ensembl NCBI GeneCards UniProt Show fit	vesicle associated membrane protein 3
chr1_-_179877790 Show fit	11.04	ENST00000495650.1 ENST00000367612.7 ENST00000482587.5 ENST00000609928.6	TOR1AIP2 Links Ensembl NCBI GeneCards UniProt Show fit	torsin 1A interacting protein 2
chr21_-_26170654 Show fit	10.93	ENST00000439274.6 ENST00000358918.7 ENST00000354192.7 ENST00000348990.9 ENST00000346798.8 ENST00000357903.7	APP Links Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein
chr11_+_69641146 Show fit	10.69	ENST00000227507.3 ENST00000536559.1	CCND1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin D1
chr3_-_123884290 Show fit	10.67	ENST00000346322.9 ENST00000360772.7 ENST00000360304.8	MYLK Links Ensembl NCBI GeneCards UniProt Show fit	myosin light chain kinase
chr9_+_111631354 Show fit	10.54	ENST00000374294.3	DNAJC25-GNG10 Links Ensembl NCBI GeneCards UniProt Show fit	DNAJC25-GNG10 readthrough
chr2_-_39437264 Show fit	10.03	ENST00000263881.8 ENST00000341681.9	MAP4K3 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 3
chr8_+_125430333 Show fit	9.89	ENST00000311922.4	TRIB1 Links Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 1
chr1_-_211579064 Show fit	9.69	ENST00000367001.5	SLC30A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 30 member 1
chr22_+_32801697 Show fit	9.48	ENST00000266085.7	TIMP3 Links Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 3
chr2_-_173965356 Show fit	9.17	ENST00000310015.12	SP3 Links Ensembl NCBI GeneCards UniProt Show fit	Sp3 transcription factor
chr6_-_81752671 Show fit	8.36	ENST00000320172.11 ENST00000369754.7 ENST00000369756.3	TENT5A Links Ensembl NCBI GeneCards UniProt Show fit	terminal nucleotidyltransferase 5A
chr2_-_157874976 Show fit	8.24	ENST00000682025.1 ENST00000683487.1 ENST00000682300.1 ENST00000683441.1 ENST00000684595.1 ENST00000683426.1 ENST00000683820.1 ENST00000263640.7	ACVR1 Links Ensembl NCBI GeneCards UniProt Show fit	activin A receptor type 1
chr17_+_59619885 Show fit	8.20	ENST00000269122.8 ENST00000580081.1 ENST00000579456.5	CLTC Links Ensembl NCBI GeneCards UniProt Show fit	clathrin heavy chain
chr11_-_65900413 Show fit	8.16	ENST00000448083.6 ENST00000531493.5 ENST00000532401.1	FOSL1 Links Ensembl NCBI GeneCards UniProt Show fit	FOS like 1, AP-1 transcription factor subunit
chr8_+_63168597 Show fit	7.97	ENST00000539294.6 ENST00000621957.4 ENST00000517371.5 ENST00000621413.4 ENST00000612880.4	YTHDF3 Links Ensembl NCBI GeneCards UniProt Show fit	YTH N6-methyladenosine RNA binding protein 3
chr5_+_179698906 Show fit	7.71	ENST00000452673.6 ENST00000680614.1 ENST00000680812.1 ENST00000681265.1 ENST00000680894.1 ENST00000681894.1 ENST00000679642.1 ENST00000680827.1 ENST00000680984.1 ENST00000680042.1 ENST00000681476.1 ENST00000681072.1 ENST00000247461.9 ENST00000502673.6 ENST00000513246.6 ENST00000680618.1 ENST00000680092.1 ENST00000506654.6	CANX Links Ensembl NCBI GeneCards UniProt Show fit	calnexin
chr9_-_14314067 Show fit	7.69	ENST00000397575.7	NFIB Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr2_+_46542474 Show fit	7.69	ENST00000238738.9	RHOQ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member Q
chr13_+_99501464 Show fit	7.65	ENST00000376387.5	TM9SF2 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane 9 superfamily member 2
chr3_-_33440343 Show fit	7.61	ENST00000283629.8	UBP1 Links Ensembl NCBI GeneCards UniProt Show fit	upstream binding protein 1
chr4_+_41935423 Show fit	7.51	ENST00000504986.6	TMEM33 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 33
chr21_-_41926680 Show fit	7.31	ENST00000329623.11	C2CD2 Links Ensembl NCBI GeneCards UniProt Show fit	C2 calcium dependent domain containing 2
chr7_-_6484057 Show fit	7.28	ENST00000490996.1 ENST00000258739.9 ENST00000436575.5	KDELR2 Links Ensembl NCBI GeneCards UniProt Show fit DAGLB Links Ensembl NCBI GeneCards UniProt Show fit	KDEL endoplasmic reticulum protein retention receptor 2 diacylglycerol lipase beta
chr10_+_86756580 Show fit	7.26	ENST00000372037.8	BMPR1A Links Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein receptor type 1A
chr10_+_61901678 Show fit	7.23	ENST00000644638.1 ENST00000681100.1 ENST00000279873.12	ARID5B Links Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 5B
chr10_+_73998104 Show fit	7.20	ENST00000372755.7 ENST00000211998.10	VCL Links Ensembl NCBI GeneCards UniProt Show fit	vinculin
chr1_+_24745396 Show fit	7.16	ENST00000374379.9	CLIC4 Links Ensembl NCBI GeneCards UniProt Show fit	chloride intracellular channel 4
chr15_+_100879822 Show fit	7.13	ENST00000329841.10 ENST00000557963.1 ENST00000346623.6	ALDH1A3 Links Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family member A3
chr2_+_181891697 Show fit	7.08	ENST00000431877.7	ITPRID2 Links Ensembl NCBI GeneCards UniProt Show fit	ITPR interacting domain containing 2
chr5_+_122775062 Show fit	6.92	ENST00000379516.7 ENST00000505934.5 ENST00000514949.1	SNX2 Links Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 2
chr21_+_33403391 Show fit	6.82	ENST00000290219.11 ENST00000381995.5	IFNGR2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr2_-_241272812 Show fit	6.78	ENST00000427007.5 ENST00000458564.5 ENST00000452065.5 ENST00000427183.6 ENST00000426343.5 ENST00000422080.5 ENST00000449504.5 ENST00000449864.5 ENST00000391975.5	HDLBP Links Ensembl NCBI GeneCards UniProt Show fit	high density lipoprotein binding protein
chr17_-_1400168 Show fit	6.69	ENST00000573026.1 ENST00000575977.1 ENST00000571732.5 ENST00000264335.13	YWHAE Links Ensembl NCBI GeneCards UniProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
chr2_-_61538313 Show fit	6.67	ENST00000677803.1 ENST00000677239.1 ENST00000401558.7	XPO1 Links Ensembl NCBI GeneCards UniProt Show fit	exportin 1
chr3_-_160565560 Show fit	6.57	ENST00000334256.9 ENST00000676866.1 ENST00000469804.1	KPNA4 Links Ensembl NCBI GeneCards UniProt Show fit	karyopherin subunit alpha 4
chr3_-_177196451 Show fit	6.57	ENST00000430069.5 ENST00000630796.2 ENST00000428970.5	TBL1XR1 Links Ensembl NCBI GeneCards UniProt Show fit	TBL1X receptor 1
chr6_-_24719146 Show fit	6.41	ENST00000378119.9	C6orf62 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 6 open reading frame 62
chr16_+_3020359 Show fit	6.36	ENST00000341627.5 ENST00000326577.9 ENST00000575124.1 ENST00000575836.1	TNFRSF12A Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 12A
chrX_-_20266834 Show fit	6.27	ENST00000379565.9	RPS6KA3 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr8_-_143939543 Show fit	6.26	ENST00000345136.8	PLEC Links Ensembl NCBI GeneCards UniProt Show fit	plectin
chr3_-_72446623 Show fit	6.18	ENST00000477973.4	RYBP Links Ensembl NCBI GeneCards UniProt Show fit	RING1 and YY1 binding protein
chr19_+_54190268 Show fit	6.10	ENST00000429671.7 ENST00000302937.8 ENST00000667261.1	TSEN34 Links Ensembl NCBI GeneCards UniProt Show fit	tRNA splicing endonuclease subunit 34
chr17_+_28335718 Show fit	6.06	ENST00000226225.7	TNFAIP1 Links Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 1
chr11_+_34621065 Show fit	6.05	ENST00000257831.8	EHF Links Ensembl NCBI GeneCards UniProt Show fit	ETS homologous factor
chr15_+_65869535 Show fit	6.02	ENST00000569896.1	RAB11A Links Ensembl NCBI GeneCards UniProt Show fit	RAB11A, member RAS oncogene family
chr1_+_93448155 Show fit	5.84	ENST00000370253.6	FNBP1L Links Ensembl NCBI GeneCards UniProt Show fit	formin binding protein 1 like
chr1_+_86704564 Show fit	5.83	ENST00000616170.4 ENST00000535010.5 ENST00000370558.8	SH3GLB1 Links Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing GRB2 like, endophilin B1
chr9_+_36190856 Show fit	5.74	ENST00000433436.6 ENST00000538225.5 ENST00000540080.5	CLTA Links Ensembl NCBI GeneCards UniProt Show fit	clathrin light chain A
chr1_+_215567279 Show fit	5.64	ENST00000259154.9	KCTD3 Links Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 3
chr2_-_20051610 Show fit	5.34	ENST00000175091.5	LAPTM4A Links Ensembl NCBI GeneCards UniProt Show fit	lysosomal protein transmembrane 4 alpha
chrX_+_147911943 Show fit	5.22	ENST00000621453.4 ENST00000218200.12 ENST00000370471.7 ENST00000440235.6 ENST00000370477.5 ENST00000621987.4	FMR1 Links Ensembl NCBI GeneCards UniProt Show fit	FMRP translational regulator 1
chr17_-_82648428 Show fit	5.19	ENST00000392325.9	WDR45B Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 45B
chr17_-_21214122 Show fit	5.15	ENST00000317635.6	TMEM11 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 11
chr3_+_180912656 Show fit	5.10	ENST00000357559.9 ENST00000491062.5 ENST00000468861.5 ENST00000445140.6 ENST00000484958.5	FXR1 Links Ensembl NCBI GeneCards UniProt Show fit	FMR1 autosomal homolog 1
chr6_+_25279359 Show fit	5.04	ENST00000329474.7	CARMIL1 Links Ensembl NCBI GeneCards UniProt Show fit	capping protein regulator and myosin 1 linker 1
chr17_+_1829981 Show fit	5.00	ENST00000254719.10	RPA1 Links Ensembl NCBI GeneCards UniProt Show fit	replication protein A1
chr10_-_32056376 Show fit	4.93	ENST00000302418.5	KIF5B Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 5B
chr17_-_1456149 Show fit	4.85	ENST00000574295.1 ENST00000398970.5 ENST00000300574.3	CRK Links Ensembl NCBI GeneCards UniProt Show fit	CRK proto-oncogene, adaptor protein
chr15_+_90388234 Show fit	4.85	ENST00000268182.10 ENST00000560738.1 ENST00000560418.1	IQGAP1 Links Ensembl NCBI GeneCards UniProt Show fit	IQ motif containing GTPase activating protein 1
chr16_-_73048104 Show fit	4.83	ENST00000268489.10	ZFHX3 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger homeobox 3
chr13_-_76886397 Show fit	4.75	ENST00000377474.4	KCTD12 Links Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 12
chr5_+_80407994 Show fit	4.71	ENST00000338008.9 ENST00000510158.5	ZFYVE16 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger FYVE-type containing 16
chr16_-_85688912 Show fit	4.68	ENST00000253462.8	GINS2 Links Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 2
chr1_+_78004930 Show fit	4.64	ENST00000370763.6	DNAJB4 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B4
chr12_-_46372763 Show fit	4.56	ENST00000256689.10	SLC38A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38 member 2
chr10_+_5684828 Show fit	4.44	ENST00000328090.9 ENST00000496681.5	TASOR2 Links Ensembl NCBI GeneCards UniProt Show fit	transcription activation suppressor family member 2
chr3_+_33798557 Show fit	4.40	ENST00000457054.6 ENST00000413073.1 ENST00000307296.8	PDCD6IP Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 6 interacting protein
chr16_+_83807958 Show fit	4.38	ENST00000433866.7 ENST00000570259.1	HSBP1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock factor binding protein 1
chr7_+_130070518 Show fit	4.28	ENST00000335420.10 ENST00000463413.1	KLHDC10 Links Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 10
chr5_+_179732811 Show fit	4.14	ENST00000292599.4	MAML1 Links Ensembl NCBI GeneCards UniProt Show fit	mastermind like transcriptional coactivator 1
chr10_+_132537778 Show fit	4.13	ENST00000368594.8	INPP5A Links Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-5-phosphatase A
chr2_-_65432591 Show fit	4.09	ENST00000356388.9	SPRED2 Links Ensembl NCBI GeneCards UniProt Show fit	sprouty related EVH1 domain containing 2
chr1_-_56579555 Show fit	4.01	ENST00000371250.4	PLPP3 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase 3
chr16_-_66751591 Show fit	3.96	ENST00000440564.6 ENST00000443351.6 ENST00000566150.5 ENST00000258198.7	DYNC1LI2 Links Ensembl NCBI GeneCards UniProt Show fit	dynein cytoplasmic 1 light intermediate chain 2
chr19_-_4400418 Show fit	3.87	ENST00000598564.5 ENST00000417295.6 ENST00000269886.7	SH3GL1 Links Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing GRB2 like 1, endophilin A2
chr6_-_16761447 Show fit	3.84	ENST00000244769.8 ENST00000436367.6	ATXN1 Links Ensembl NCBI GeneCards UniProt Show fit	ataxin 1
chr1_+_200739542 Show fit	3.83	ENST00000358823.6	CAMSAP2 Links Ensembl NCBI GeneCards UniProt Show fit	calmodulin regulated spectrin associated protein family member 2
chr12_+_111405861 Show fit	3.74	ENST00000341259.7	SH2B3 Links Ensembl NCBI GeneCards UniProt Show fit	SH2B adaptor protein 3
chr8_-_61714498 Show fit	3.67	ENST00000519234.5 ENST00000379449.10 ENST00000518068.5 ENST00000517856.5 ENST00000379454.9 ENST00000356457.9	ASPH Links Ensembl NCBI GeneCards UniProt Show fit	aspartate beta-hydroxylase
chr9_-_121201836 Show fit	3.65	ENST00000373840.9	RAB14 Links Ensembl NCBI GeneCards UniProt Show fit	RAB14, member RAS oncogene family
chr13_-_110307131 Show fit	3.62	ENST00000543140.6 ENST00000375820.10	COL4A1 Links Ensembl NCBI GeneCards UniProt Show fit	collagen type IV alpha 1 chain
chr7_-_23470469 Show fit	3.60	ENST00000258729.8	IGF2BP3 Links Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 2 mRNA binding protein 3
chr17_+_7572818 Show fit	3.54	ENST00000293831.13 ENST00000582169.5 ENST00000578754.5 ENST00000578495.5 ENST00000585024.5 ENST00000583802.5 ENST00000577269.5 ENST00000584784.5 ENST00000582746.5 ENST00000581621.1	EIF4A1 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000264772.6 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4A1 novel transcript
chr1_+_32013848 Show fit	3.52	ENST00000327300.12 ENST00000492989.1	KHDRBS1 Links Ensembl NCBI GeneCards UniProt Show fit	KH RNA binding domain containing, signal transduction associated 1
chrX_-_20141810 Show fit	3.41	ENST00000379593.1 ENST00000379607.10	EIF1AX Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1A X-linked
chr3_+_105366877 Show fit	3.37	ENST00000306107.9	ALCAM Links Ensembl NCBI GeneCards UniProt Show fit	activated leukocyte cell adhesion molecule
chr4_+_98995709 Show fit	3.35	ENST00000296411.11 ENST00000625963.1	METAP1 Links Ensembl NCBI GeneCards UniProt Show fit	methionyl aminopeptidase 1
chr3_-_98901656 Show fit	3.23	ENST00000326840.11	DCBLD2 Links Ensembl NCBI GeneCards UniProt Show fit	discoidin, CUB and LCCL domain containing 2
chr8_+_60516947 Show fit	3.17	ENST00000262646.12	RAB2A Links Ensembl NCBI GeneCards UniProt Show fit	RAB2A, member RAS oncogene family
chr1_-_31065671 Show fit	3.10	ENST00000440538.6 ENST00000424085.6 ENST00000257075.9 ENST00000373747.7 ENST00000426105.7 ENST00000525843.5 ENST00000373742.6	PUM1 Links Ensembl NCBI GeneCards UniProt Show fit	pumilio RNA binding family member 1
chr3_-_45995807 Show fit	3.06	ENST00000535325.5 ENST00000296137.7	FYCO1 Links Ensembl NCBI GeneCards UniProt Show fit	FYVE and coiled-coil domain autophagy adaptor 1
chr5_-_115625972 Show fit	2.98	ENST00000333314.3 ENST00000456936.4	TMED7-TICAM2 Links Ensembl NCBI GeneCards UniProt Show fit TMED7 Links Ensembl NCBI GeneCards UniProt Show fit	TMED7-TICAM2 readthrough transmembrane p24 trafficking protein 7
chr3_-_50359480 Show fit	2.87	ENST00000266025.4	TMEM115 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 115
chr17_-_62065248 Show fit	2.86	ENST00000397786.7	MED13 Links Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 13
chr3_+_150408314 Show fit	2.82	ENST00000361875.7	TSC22D2 Links Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 2
chr6_-_113971120 Show fit	2.78	ENST00000520895.5 ENST00000521163.5 ENST00000524334.1 ENST00000519065.6 ENST00000368632.6	HDAC2 Links Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 2
chr12_-_54419259 Show fit	2.76	ENST00000293379.9	ITGA5 Links Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 5
chr2_+_46698909 Show fit	2.72	ENST00000650611.1 ENST00000306503.5	LINC01118 Links Ensembl NCBI GeneCards UniProt Show fit SOCS5 Links Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 1118 suppressor of cytokine signaling 5
chr1_-_243850070 Show fit	2.71	ENST00000366539.6 ENST00000672578.1	AKT3 Links Ensembl NCBI GeneCards UniProt Show fit	AKT serine/threonine kinase 3
chr10_-_59906509 Show fit	2.68	ENST00000263102.7	CCDC6 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 6
chr11_+_118606428 Show fit	2.67	ENST00000361417.6	PHLDB1 Links Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology like domain family B member 1
chr11_-_65614195 Show fit	2.66	ENST00000309100.8 ENST00000529839.1 ENST00000526293.1	MAP3K11 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 11
chr14_+_54567612 Show fit	2.59	ENST00000251091.9 ENST00000392067.7 ENST00000631086.2	SAMD4A Links Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 4A
chr9_-_83980578 Show fit	2.57	ENST00000376281.8	HNRNPK Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein K
chr15_+_90265634 Show fit	2.54	ENST00000379095.5	NGRN Links Ensembl NCBI GeneCards UniProt Show fit	neugrin, neurite outgrowth associated
chr1_+_35268663 Show fit	2.53	ENST00000314607.11	ZMYM4 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger MYM-type containing 4
chr16_+_56932134 Show fit	2.51	ENST00000439977.7 ENST00000300302.9 ENST00000344114.8 ENST00000379792.6	HERPUD1 Links Ensembl NCBI GeneCards UniProt Show fit	homocysteine inducible ER protein with ubiquitin like domain 1
chr3_+_129249594 Show fit	2.48	ENST00000314797.10	COPG1 Links Ensembl NCBI GeneCards UniProt Show fit	COPI coat complex subunit gamma 1
chr14_-_63543328 Show fit	2.47	ENST00000337537.8	PPP2R5E Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit B'epsilon
chr1_-_231422261 Show fit	2.41	ENST00000366641.4	EGLN1 Links Ensembl NCBI GeneCards UniProt Show fit	egl-9 family hypoxia inducible factor 1
chr17_+_40219276 Show fit	2.40	ENST00000583268.1 ENST00000323571.9	WIPF2 Links Ensembl NCBI GeneCards UniProt Show fit	WAS/WASL interacting protein family member 2
chr5_-_180353317 Show fit	2.39	ENST00000253778.13	GFPT2 Links Ensembl NCBI GeneCards UniProt Show fit	glutamine-fructose-6-phosphate transaminase 2
chr2_+_190649062 Show fit	2.39	ENST00000409581.5 ENST00000337386.10	NAB1 Links Ensembl NCBI GeneCards UniProt Show fit	NGFI-A binding protein 1
chrX_-_74614612 Show fit	2.38	ENST00000349225.2 ENST00000332687.11	RLIM Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein, LIM domain interacting
chr1_-_202808406 Show fit	2.33	ENST00000650569.1 ENST00000367265.9 ENST00000649770.1	KDM5B Links Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 5B
chr5_-_143403611 Show fit	2.32	ENST00000394464.7 ENST00000231509.7	NR3C1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 3 group C member 1
chr6_-_52577012 Show fit	2.25	ENST00000182527.4	TRAM2 Links Ensembl NCBI GeneCards UniProt Show fit	translocation associated membrane protein 2
chr1_+_201829132 Show fit	2.25	ENST00000361565.9	IPO9 Links Ensembl NCBI GeneCards UniProt Show fit	importin 9
chr15_+_58987652 Show fit	2.23	ENST00000348370.9 ENST00000559160.1	RNF111 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 111
chr1_-_243255170 Show fit	2.22	ENST00000366542.6	CEP170 Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 170
chrX_-_41922992 Show fit	2.19	ENST00000646120.2 ENST00000421587.8 ENST00000644770.1 ENST00000645566.1 ENST00000378166.9 ENST00000378158.6 ENST00000644219.1 ENST00000442742.7 ENST00000644347.1	CASK Links Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent serine protein kinase
chr10_-_97687191 Show fit	2.17	ENST00000370626.4	AVPI1 Links Ensembl NCBI GeneCards UniProt Show fit	arginine vasopressin induced 1
chr9_-_16870662 Show fit	2.07	ENST00000380672.9	BNC2 Links Ensembl NCBI GeneCards UniProt Show fit	basonuclin 2
chr10_-_100185993 Show fit	2.04	ENST00000421367.7 ENST00000370408.2 ENST00000407654.7	ERLIN1 Links Ensembl NCBI GeneCards UniProt Show fit	ER lipid raft associated 1
chr12_-_25250879 Show fit	1.98	ENST00000256078.10 ENST00000311936.8 ENST00000556131.1 ENST00000557334.5	KRAS Links Ensembl NCBI GeneCards UniProt Show fit	KRAS proto-oncogene, GTPase
chr6_-_116060859 Show fit	1.98	ENST00000606080.2	FRK Links Ensembl NCBI GeneCards UniProt Show fit	fyn related Src family tyrosine kinase
chr16_-_4116403 Show fit	1.80	ENST00000294016.8	ADCY9 Links Ensembl NCBI GeneCards UniProt Show fit	adenylate cyclase 9
chr14_+_57268963 Show fit	1.78	ENST00000261558.8	AP5M1 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 5 subunit mu 1
chr7_-_13989658 Show fit	1.76	ENST00000430479.6 ENST00000433547.1 ENST00000405192.6	ETV1 Links Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chr15_+_84980440 Show fit	1.76	ENST00000310298.8 ENST00000557957.5	PDE8A Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 8A
chr14_+_102592611 Show fit	1.74	ENST00000262241.7	RCOR1 Links Ensembl NCBI GeneCards UniProt Show fit	REST corepressor 1
chr1_+_65147514 Show fit	1.74	ENST00000545314.5	AK4 Links Ensembl NCBI GeneCards UniProt Show fit	adenylate kinase 4
chr20_-_17682234 Show fit	1.69	ENST00000377813.6 ENST00000377807.6 ENST00000360807.8 ENST00000398782.2	RRBP1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosome binding protein 1
chr12_+_120446418 Show fit	1.66	ENST00000551765.6 ENST00000229384.5	GATC Links Ensembl NCBI GeneCards UniProt Show fit	glutamyl-tRNA amidotransferase subunit C
chr5_-_16936231 Show fit	1.63	ENST00000507288.1 ENST00000274203.13 ENST00000513610.6	MYO10 Links Ensembl NCBI GeneCards UniProt Show fit	myosin X
chr7_-_88220025 Show fit	1.56	ENST00000419179.5 ENST00000265729.7	SRI Links Ensembl NCBI GeneCards UniProt Show fit	sorcin
chr4_-_138242325 Show fit	1.53	ENST00000280612.9	SLC7A11 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 11
chr2_+_147845020 Show fit	1.50	ENST00000241416.12	ACVR2A Links Ensembl NCBI GeneCards UniProt Show fit	activin A receptor type 2A
chr9_+_130579556 Show fit	1.44	ENST00000319725.10	FUBP3 Links Ensembl NCBI GeneCards UniProt Show fit	far upstream element binding protein 3
chr1_+_88684222 Show fit	1.43	ENST00000316005.11 ENST00000370521.8	PKN2 Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase N2
chr1_-_92792396 Show fit	1.42	ENST00000370331.5 ENST00000540033.2	EVI5 Links Ensembl NCBI GeneCards UniProt Show fit	ecotropic viral integration site 5
chr12_+_120438107 Show fit	1.41	ENST00000229379.3 ENST00000551806.1	COX6A1 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000111780.8 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 6A1 novel protein
chr12_-_89656051 Show fit	1.38	ENST00000261173.6	ATP2B1 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase plasma membrane Ca2+ transporting 1
chr12_-_24949026 Show fit	1.35	ENST00000539780.5 ENST00000546285.1 ENST00000342945.9 ENST00000261192.12	BCAT1 Links Ensembl NCBI GeneCards UniProt Show fit	branched chain amino acid transaminase 1
chr3_-_15859771 Show fit	1.35	ENST00000399451.6	ANKRD28 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 28
chr2_+_105744876 Show fit	1.33	ENST00000233154.9 ENST00000451463.6	NCK2 Links Ensembl NCBI GeneCards UniProt Show fit	NCK adaptor protein 2
chr12_-_105236074 Show fit	1.26	ENST00000551662.5 ENST00000553097.5 ENST00000258530.8	APPL2 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
chr2_+_207529892 Show fit	1.25	ENST00000432329.6 ENST00000445803.5	CREB1 Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 1
chr1_+_186828941 Show fit	1.16	ENST00000367466.4	PLA2G4A Links Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group IVA
chr1_-_37859583 Show fit	1.12	ENST00000373036.5	MTF1 Links Ensembl NCBI GeneCards UniProt Show fit	metal regulatory transcription factor 1
chr2_+_66435558 Show fit	1.04	ENST00000488550.5	MEIS1 Links Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 1
chr10_-_102502669 Show fit	0.97	ENST00000487599.1	ACTR1A Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 1A
chr7_-_99144053 Show fit	0.95	ENST00000361125.1 ENST00000361368.7	SMURF1 Links Ensembl NCBI GeneCards UniProt Show fit	SMAD specific E3 ubiquitin protein ligase 1
chr19_-_55370455 Show fit	0.93	ENST00000264563.7 ENST00000585513.1 ENST00000590625.5	IL11 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 11
chr4_-_184826030 Show fit	0.93	ENST00000507295.5 ENST00000504900.5 ENST00000454703.6	ACSL1 Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long chain family member 1
chr11_-_77820706 Show fit	0.88	ENST00000440064.2 ENST00000528095.5 ENST00000308488.11	RSF1 Links Ensembl NCBI GeneCards UniProt Show fit	remodeling and spacing factor 1
chr6_+_17600273 Show fit	0.87	ENST00000259963.4	FAM8A1 Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 8 member A1
chr5_-_157059109 Show fit	0.82	ENST00000523175.6 ENST00000522693.5	HAVCR1 Links Ensembl NCBI GeneCards UniProt Show fit	hepatitis A virus cellular receptor 1
chr12_+_48122574 Show fit	0.80	ENST00000549022.5 ENST00000547587.5 ENST00000312352.11	PFKM Links Ensembl NCBI GeneCards UniProt Show fit	phosphofructokinase, muscle
chr12_+_49367440 Show fit	0.79	ENST00000552918.6 ENST00000553127.5 ENST00000321898.10	SPATS2 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated serine rich 2
chr9_-_122828539 Show fit	0.79	ENST00000259467.9	PDCL Links Ensembl NCBI GeneCards UniProt Show fit	phosducin like
chr4_-_41214602 Show fit	0.75	ENST00000508676.5 ENST00000506352.5 ENST00000295974.12	APBB2 Links Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein binding family B member 2
chr2_-_112784486 Show fit	0.74	ENST00000263339.4	IL1A Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 alpha
chr12_+_67269328 Show fit	0.73	ENST00000545606.6	CAND1 Links Ensembl NCBI GeneCards UniProt Show fit	cullin associated and neddylation dissociated 1
chr6_-_33298909 Show fit	0.70	ENST00000497454.6	RGL2 Links Ensembl NCBI GeneCards UniProt Show fit	ral guanine nucleotide dissociation stimulator like 2
chr22_+_31212207 Show fit	0.68	ENST00000406516.5 ENST00000331728.9	LIMK2 Links Ensembl NCBI GeneCards UniProt Show fit	LIM domain kinase 2
chr16_+_85613252 Show fit	0.68	ENST00000253458.12 ENST00000393243.5	GSE1 Links Ensembl NCBI GeneCards UniProt Show fit	Gse1 coiled-coil protein
chr15_+_90529862 Show fit	0.64	ENST00000268184.11 ENST00000420329.6	CRTC3 Links Ensembl NCBI GeneCards UniProt Show fit	CREB regulated transcription coactivator 3
chr17_+_81683963 Show fit	0.63	ENST00000676462.1 ENST00000679336.1 ENST00000678196.1 ENST00000677243.1 ENST00000677044.1 ENST00000677109.1 ENST00000677484.1 ENST00000678105.1 ENST00000677209.1 ENST00000329138.9 ENST00000677225.1 ENST00000678866.1 ENST00000676729.1 ENST00000572392.2 ENST00000577012.1	HGS Links Ensembl NCBI GeneCards UniProt Show fit	hepatocyte growth factor-regulated tyrosine kinase substrate
chr16_+_22297375 Show fit	0.61	ENST00000615879.4 ENST00000299853.10 ENST00000564209.5 ENST00000565358.5 ENST00000418581.6 ENST00000564883.5 ENST00000359210.8 ENST00000563024.5	POLR3E Links Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase III subunit E
chr1_-_108963413 Show fit	0.61	ENST00000676454.1 ENST00000675790.1 ENST00000674849.1 ENST00000675956.1 ENST00000369976.5 ENST00000675584.1 ENST00000302500.5 ENST00000356970.6 ENST00000676392.1 ENST00000676059.1 ENST00000675571.1 ENST00000675018.1 ENST00000674527.1 ENST00000369968.7 ENST00000369969.7 ENST00000675508.1 ENST00000675650.1 ENST00000369970.8 ENST00000675654.1 ENST00000357393.6	CLCC1 Links Ensembl NCBI GeneCards UniProt Show fit AKNAD1 Links Ensembl NCBI GeneCards UniProt Show fit	chloride channel CLIC like 1 AKNA domain containing 1
chr7_-_24980148 Show fit	0.57	ENST00000313367.7	OSBPL3 Links Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein like 3

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.4	19.3	GO:0006097	glyoxylate cycle(GO:0006097)
4.6	18.4	GO:0031179	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
3.4	13.8	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
3.3	9.9	GO:0045645	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
2.8	16.7	GO:0070101	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
2.8	19.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
2.7	8.2	GO:0060957	endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
2.6	13.1	GO:2000017	glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) positive regulation of determination of dorsal identity(GO:2000017)
2.5	25.5	GO:0006621	protein retention in ER lumen(GO:0006621)
2.5	5.0	GO:2000812	regulation of barbed-end actin filament capping(GO:2000812)
2.4	7.1	GO:0060166	olfactory pit development(GO:0060166)
2.4	9.5	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
2.2	6.7	GO:1902309	regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
2.2	22.2	GO:0030043	actin filament fragmentation(GO:0030043)
2.0	8.2	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
1.9	5.8	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
1.9	7.5	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.8	10.9	GO:0048669	microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
1.8	7.3	GO:0048378	tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
1.7	5.2	GO:0044830	modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
1.6	9.7	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
1.6	11.1	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
1.5	6.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.5	6.0	GO:0010796	regulation of multivesicular body size(GO:0010796)
1.5	28.2	GO:0070831	basement membrane assembly(GO:0070831)
1.5	4.4	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
1.4	13.0	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
1.4	13.0	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.4	2.8	GO:0061198	fungiform papilla formation(GO:0061198)
1.4	4.1	GO:0003162	atrioventricular node development(GO:0003162)
1.4	8.2	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
1.3	11.4	GO:0031584	activation of phospholipase D activity(GO:0031584)
1.1	15.9	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.1	6.4	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.0	10.7	GO:0033327	Leydig cell differentiation(GO:0033327)
1.0	4.8	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.9	12.2	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.9	11.0	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.9	3.7	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.9	9.2	GO:0060136	enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.9	3.6	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.9	7.2	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.9	8.0	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383)
0.9	3.5	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
0.7	6.6	GO:0060613	fat pad development(GO:0060613)
0.7	7.7	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7	2.7	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.7	6.1	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.7	2.0	GO:0021897	forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.6	2.6	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.6	13.9	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.6	6.7	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.6	2.4	GO:0030821	negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.6	2.3	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.6	7.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.6	1.7	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.5	8.2	GO:0009629	response to gravity(GO:0009629)
0.5	13.0	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.5	3.7	GO:0032328	alanine transport(GO:0032328)
0.5	7.7	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.5	6.9	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.5	12.3	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.5	27.4	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.5	6.2	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.5	4.7	GO:1902969	mitotic DNA replication(GO:1902969)
0.5	2.3	GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.5	3.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.4	5.8	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.4	2.7	GO:0007256	activation of JNKK activity(GO:0007256)
0.4	4.8	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.4	2.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4	10.0	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.4	17.9	GO:0006294	nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.4	7.7	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.4	9.9	GO:0061157	mRNA destabilization(GO:0061157)
0.4	6.8	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.3	3.9	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.3	0.9	GO:0034201	response to oleic acid(GO:0034201)
0.3	4.0	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.3	3.4	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.3	4.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.3	1.2	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.3	1.4	GO:0009099	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3	2.4	GO:0007549	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.3	6.6	GO:0019054	modulation by virus of host process(GO:0019054)
0.3	2.3	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.3	4.1	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.2	5.7	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.2	6.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	5.1	GO:0060148	positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2	1.4	GO:1990034	calcium ion export from cell(GO:1990034)
0.2	7.6	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.2	5.2	GO:0044804	nucleophagy(GO:0044804)
0.2	2.7	GO:0045793	positive regulation of cell size(GO:0045793)
0.2	1.6	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2	1.5	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.2	2.5	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.2	2.5	GO:0051683	establishment of Golgi localization(GO:0051683)
0.2	2.8	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.2	0.8	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2	1.7	GO:0070933	histone H4 deacetylation(GO:0070933)
0.2	1.7	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.2	6.8	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2	3.2	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.2	3.7	GO:0006895	Golgi to endosome transport(GO:0006895)
0.2	0.9	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.1	0.7	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.1	0.7	GO:0010265	SCF complex assembly(GO:0010265)
0.1	3.4	GO:0048846	axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1	0.1	GO:0071676	negative regulation of mononuclear cell migration(GO:0071676)
0.1	5.3	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	0.9	GO:0016584	nucleosome positioning(GO:0016584)
0.1	3.8	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	2.1	GO:0043586	tongue development(GO:0043586)
0.1	4.0	GO:0051642	centrosome localization(GO:0051642)
0.1	4.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1	2.4	GO:2000272	negative regulation of receptor activity(GO:2000272)
0.1	1.8	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	5.9	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1	1.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	13.3	GO:2001020	regulation of response to DNA damage stimulus(GO:2001020)
0.1	0.6	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	0.7	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	4.6	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.1	1.8	GO:1903206	negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1	1.0	GO:0060044	megakaryocyte development(GO:0035855) negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1	2.2	GO:0046710	GDP metabolic process(GO:0046710)
0.1	2.4	GO:0014037	Schwann cell differentiation(GO:0014037)
0.1	1.5	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.1	4.2	GO:0048207	vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	4.4	GO:1900034	regulation of cellular response to heat(GO:1900034)
0.0	7.2	GO:0001889	liver development(GO:0001889)
0.0	13.8	GO:0007411	axon guidance(GO:0007411)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442)
0.0	1.4	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.3	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	1.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	9.3	GO:0010506	regulation of autophagy(GO:0010506)
0.0	3.3	GO:0019079	viral genome replication(GO:0019079)
0.0	3.6	GO:0017148	negative regulation of translation(GO:0017148)
0.0	1.1	GO:0046686	response to cadmium ion(GO:0046686)
0.0	8.6	GO:0043687	post-translational protein modification(GO:0043687)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	2.7	GO:0030308	negative regulation of cell growth(GO:0030308)
0.0	1.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.6	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	4.1	GO:0051260	protein homooligomerization(GO:0051260)
0.0	1.3	GO:0006970	response to osmotic stress(GO:0006970)
0.0	2.0	GO:0051168	nuclear export(GO:0051168)
0.0	0.2	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.5	25.5	GO:0043259	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
3.2	12.9	GO:0071942	XPC complex(GO:0071942)
3.2	15.9	GO:0097149	centralspindlin complex(GO:0097149)
2.2	13.1	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
2.1	8.2	GO:0048179	activin receptor complex(GO:0048179)
1.7	5.2	GO:1902737	dendritic filopodium(GO:1902737)
1.6	10.9	GO:1990812	growth cone filopodium(GO:1990812)
1.5	23.7	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
1.4	13.9	GO:0071439	clathrin complex(GO:0071439)
1.2	6.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
1.2	6.0	GO:0098837	postsynaptic recycling endosome(GO:0098837)
1.2	15.2	GO:0031209	SCAR complex(GO:0031209)
1.2	4.7	GO:0000811	GINS complex(GO:0000811)
1.0	13.0	GO:0000815	ESCRT III complex(GO:0000815)
1.0	6.9	GO:0030905	retromer, tubulation complex(GO:0030905)
1.0	3.8	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.9	12.3	GO:0005915	zonula adherens(GO:0005915)
0.9	2.8	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.7	5.0	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.6	1.7	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.5	15.8	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.5	7.3	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.5	36.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.5	4.9	GO:0035253	ciliary rootlet(GO:0035253)
0.5	7.7	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.5	9.5	GO:0031089	platelet dense granule lumen(GO:0031089)
0.5	4.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5	3.7	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.5	3.6	GO:0005587	collagen type IV trimer(GO:0005587)
0.4	6.7	GO:0005642	annulate lamellae(GO:0005642)
0.4	4.8	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4	7.7	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.4	7.2	GO:0005916	fascia adherens(GO:0005916)
0.4	2.5	GO:1990037	Lewy body core(GO:1990037)
0.3	19.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3	1.3	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.3	16.7	GO:1904115	axon cytoplasm(GO:1904115)
0.3	6.3	GO:0030056	hemidesmosome(GO:0030056)
0.3	2.7	GO:0045180	basal cortex(GO:0045180)
0.3	5.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.2	1.5	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	1.6	GO:0044326	dendritic spine neck(GO:0044326)
0.2	2.9	GO:0017119	Golgi transport complex(GO:0017119)
0.2	26.9	GO:0017053	transcriptional repressor complex(GO:0017053)
0.2	0.6	GO:0033565	ESCRT-0 complex(GO:0033565)
0.2	24.8	GO:0030175	filopodium(GO:0030175)
0.2	12.1	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2	5.8	GO:0000421	autophagosome membrane(GO:0000421)
0.2	14.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	3.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	19.1	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.2	5.2	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2	3.8	GO:1990752	microtubule end(GO:1990752)
0.2	6.4	GO:0002102	podosome(GO:0002102)
0.2	6.8	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.2	6.7	GO:0005871	kinesin complex(GO:0005871)
0.2	1.0	GO:0002177	manchette(GO:0002177)
0.2	3.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.2	4.0	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.2	1.4	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.8	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	15.1	GO:0042734	presynaptic membrane(GO:0042734)
0.1	16.9	GO:0043204	perikaryon(GO:0043204)
0.1	20.9	GO:0043197	dendritic spine(GO:0043197)
0.1	7.0	GO:0005801	cis-Golgi network(GO:0005801)
0.1	1.8	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	7.2	GO:0005902	microvillus(GO:0005902)
0.1	3.4	GO:0042101	T cell receptor complex(GO:0042101)
0.1	12.2	GO:0005643	nuclear pore(GO:0005643)
0.1	13.0	GO:0005796	Golgi lumen(GO:0005796)
0.1	1.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	0.9	GO:0031010	ISWI-type complex(GO:0031010)
0.1	4.6	GO:0031519	PcG protein complex(GO:0031519)
0.1	7.9	GO:0005884	actin filament(GO:0005884)
0.1	2.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	3.8	GO:0030315	T-tubule(GO:0030315)
0.1	20.6	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	4.6	GO:0042383	sarcolemma(GO:0042383)
0.0	1.8	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	6.4	GO:0001726	ruffle(GO:0001726)
0.0	3.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	5.0	GO:0016605	PML body(GO:0016605)
0.0	5.4	GO:0005938	cell cortex(GO:0005938)
0.0	9.1	GO:0031965	nuclear membrane(GO:0031965)
0.0	2.0	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	1.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	3.2	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0005846	nuclear cap binding complex(GO:0005846)
0.0	3.4	GO:0030658	transport vesicle membrane(GO:0030658)
0.0	1.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.9	GO:0044438	microbody part(GO:0044438) peroxisomal part(GO:0044439)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.5	25.5	GO:0005046	KDEL sequence binding(GO:0005046)
6.4	19.3	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
4.6	18.4	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
2.7	10.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
2.6	7.7	GO:0032427	GBD domain binding(GO:0032427)
2.0	12.2	GO:0043120	tumor necrosis factor binding(GO:0043120)
1.7	6.8	GO:0004906	interferon-gamma receptor activity(GO:0004906)
1.6	14.8	GO:0019784	NEDD8-specific protease activity(GO:0019784)
1.5	6.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
1.5	9.1	GO:0034046	poly(G) binding(GO:0034046)
1.5	8.8	GO:0098821	BMP receptor activity(GO:0098821)
1.4	6.9	GO:1990460	leptin receptor binding(GO:1990460)
1.4	8.2	GO:0016361	activin receptor activity, type I(GO:0016361)
1.4	4.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
1.2	4.9	GO:0099609	microtubule lateral binding(GO:0099609)
1.2	3.7	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
1.1	12.4	GO:0042301	phosphate ion binding(GO:0042301)
1.1	10.9	GO:0051425	PTB domain binding(GO:0051425)
1.1	20.3	GO:0045294	alpha-catenin binding(GO:0045294)
1.0	6.7	GO:0050815	phosphoserine binding(GO:0050815)
0.9	4.4	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.7	8.2	GO:0032051	clathrin light chain binding(GO:0032051)
0.7	13.0	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.7	4.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.7	8.0	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.7	2.7	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.6	9.9	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.6	2.4	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.6	7.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.6	4.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.6	2.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.6	1.7	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.5	9.7	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.5	3.6	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.5	5.1	GO:0002151	G-quadruplex RNA binding(GO:0002151) RNA strand annealing activity(GO:0033592)
0.5	10.0	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.5	13.9	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.5	22.6	GO:0050699	WW domain binding(GO:0050699)
0.5	2.3	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.5	2.3	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4	6.7	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.4	15.7	GO:0001671	ATPase activator activity(GO:0001671)
0.4	9.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.4	5.7	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.4	38.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.4	10.7	GO:0070064	proline-rich region binding(GO:0070064)
0.4	9.7	GO:0031489	myosin V binding(GO:0031489)
0.4	5.0	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.4	3.8	GO:0051011	microtubule minus-end binding(GO:0051011)
0.4	6.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.3	1.7	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3	16.7	GO:0051879	Hsp90 protein binding(GO:0051879)
0.3	7.7	GO:0034185	apolipoprotein binding(GO:0034185)
0.3	11.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3	11.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.3	7.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.3	4.7	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.3	36.0	GO:0017048	Rho GTPase binding(GO:0017048)
0.3	1.5	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3	4.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.3	2.8	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.3	1.4	GO:0052654	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2	6.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.2	2.8	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2	10.8	GO:0031593	polyubiquitin binding(GO:0031593)
0.2	1.3	GO:1990763	arrestin family protein binding(GO:1990763)
0.2	1.6	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.2	5.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2	6.3	GO:0030506	ankyrin binding(GO:0030506)
0.2	1.0	GO:0048185	activin binding(GO:0048185)
0.2	2.4	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2	2.9	GO:0042809	vitamin D receptor binding(GO:0042809)
0.2	3.6	GO:0000339	RNA cap binding(GO:0000339)
0.2	0.8	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2	10.2	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.1	7.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	1.2	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1	6.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	3.6	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	1.8	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	38.2	GO:0003714	transcription corepressor activity(GO:0003714)
0.1	4.1	GO:0042605	peptide antigen binding(GO:0042605)
0.1	2.0	GO:0030275	LRR domain binding(GO:0030275)
0.1	4.9	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.8	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	3.1	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	20.8	GO:0051015	actin filament binding(GO:0051015)
0.1	3.0	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	1.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	3.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	8.6	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1	2.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	28.8	GO:0045296	cadherin binding(GO:0045296)
0.1	2.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	2.7	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	0.7	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	3.4	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.0	1.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	1.4	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	2.6	GO:0015485	cholesterol binding(GO:0015485)
0.0	1.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	4.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	3.1	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	1.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	1.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.9	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	2.9	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	9.4	GO:0003924	GTPase activity(GO:0003924)
0.0	0.6	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.7	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	2.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	25.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.0	83.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.7	19.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.7	17.7	PID ARF 3PATHWAY	Arf1 pathway
0.5	26.7	PID BMP PATHWAY	BMP receptor signaling
0.4	8.0	PID ALK2 PATHWAY	ALK2 signaling events
0.4	18.9	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.4	13.0	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.4	14.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.3	6.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.3	12.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.3	15.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	6.3	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2	12.1	PID AURORA B PATHWAY	Aurora B signaling
0.2	15.9	PID PLK1 PATHWAY	PLK1 signaling events
0.2	12.9	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	10.0	PID TNF PATHWAY	TNF receptor signaling pathway
0.2	2.7	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2	8.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.2	10.9	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.2	2.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	7.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	3.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	6.9	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	3.7	PID EPO PATHWAY	EPO signaling pathway
0.1	3.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	5.0	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	2.7	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	6.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	1.8	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	6.9	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.1	4.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	1.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	3.1	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	4.6	PID E2F PATHWAY	E2F transcription factor network
0.1	2.8	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	2.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	6.2	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	1.2	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	9.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.7	PID CDC42 PATHWAY	CDC42 signaling events
0.0	1.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	25.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.9	19.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.7	13.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.7	28.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.6	13.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.6	19.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.6	25.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.6	10.9	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.5	17.9	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.5	9.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.5	14.8	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.5	22.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.5	7.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.5	13.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.4	12.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	17.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	1.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.3	4.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.3	6.8	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.3	6.7	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3	6.8	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.3	22.6	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.2	8.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.2	6.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	2.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	3.7	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	32.1	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.2	4.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	6.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	7.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.2	4.6	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	2.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	1.8	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	3.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	3.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	2.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	5.9	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1	0.9	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	7.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	10.1	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	2.8	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	2.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	7.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	4.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	3.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	3.4	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.6	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	3.6	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	2.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.8	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.8	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events