ISMARA results: VSX1

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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for VSX1

Z-value: 1.27

Motif logo

Transcription factors associated with VSX1

Gene Symbol	Gene ID	Gene Info
VSX1 Ensembl NCBI GeneCards UniProt	ENSG00000100987.15	VSX1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
VSX1	hg38_v1_chr20_-_25082131_25082141	-0.68	2.9e-31	Click!

Activity profile of VSX1 motif

Sorted Z-values of VSX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of VSX1

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr15_-_90994494 Show fit	36.76	ENST00000559811.1 ENST00000442656.6 ENST00000557905.5 ENST00000394249.8	PRC1 Ensembl NCBI GeneCards UniProt Show fit	protein regulator of cytokinesis 1
chr1_+_154974672 Show fit	29.16	ENST00000308987.6 ENST00000368436.1	CKS1B Ensembl NCBI GeneCards UniProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr1_-_197146620 Show fit	27.74	ENST00000367409.9 ENST00000680265.1	ASPM Ensembl NCBI GeneCards UniProt Show fit	assembly factor for spindle microtubules
chr1_+_154974653 Show fit	27.68	ENST00000368439.5	CKS1B Ensembl NCBI GeneCards UniProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr3_+_172750715 Show fit	27.28	ENST00000392692.8 ENST00000417960.5 ENST00000428567.5 ENST00000366090.6 ENST00000426894.5	ECT2 Ensembl NCBI GeneCards UniProt Show fit	epithelial cell transforming 2
chrX_+_19355582 Show fit	25.90	ENST00000379804.1	PDHA1 Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehydrogenase E1 subunit alpha 1
chr15_-_64381431 Show fit	25.57	ENST00000558008.3 ENST00000300035.9 ENST00000559519.5 ENST00000380258.6	PCLAF Ensembl NCBI GeneCards UniProt Show fit	PCNA clamp associated factor
chr20_+_45812576 Show fit	24.32	ENST00000405520.5 ENST00000617055.4	UBE2C Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 C
chr14_+_58244821 Show fit	23.96	ENST00000216455.9 ENST00000412908.6 ENST00000557508.5	PSMA3 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 3
chr5_+_178204522 Show fit	23.64	ENST00000506339.5 ENST00000358344.8 ENST00000355836.9 ENST00000514633.5 ENST00000515193.5 ENST00000506259.5 ENST00000504898.5	HNRNPAB Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein A/B
chr20_+_45812665 Show fit	23.17	ENST00000352551.9	UBE2C Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 C
chr1_-_197146688 Show fit	23.02	ENST00000294732.11	ASPM Ensembl NCBI GeneCards UniProt Show fit	assembly factor for spindle microtubules
chr20_+_45812632 Show fit	22.80	ENST00000335046.7 ENST00000356455.9 ENST00000243893.10	UBE2C Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 C
chrX_-_152830721 Show fit	22.74	ENST00000370277.5	CETN2 Ensembl NCBI GeneCards UniProt Show fit	centrin 2
chr19_+_49677228 Show fit	22.55	ENST00000454376.7 ENST00000524771.5	PRMT1 Ensembl NCBI GeneCards UniProt Show fit	protein arginine methyltransferase 1
chr17_+_1829981 Show fit	22.46	ENST00000254719.10	RPA1 Ensembl NCBI GeneCards UniProt Show fit	replication protein A1
chr5_+_33440947 Show fit	22.09	ENST00000455217.6 ENST00000265112.8	TARS1 Ensembl NCBI GeneCards UniProt Show fit	threonyl-tRNA synthetase 1
chr5_+_33440696 Show fit	21.54	ENST00000502553.5 ENST00000514259.5	TARS1 Ensembl NCBI GeneCards UniProt Show fit	threonyl-tRNA synthetase 1
chr7_-_100101915 Show fit	19.26	ENST00000621318.4 ENST00000343023.10	MCM7 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 7
chr19_+_49677055 Show fit	18.58	ENST00000534465.6 ENST00000391851.8 ENST00000610806.4	PRMT1 Ensembl NCBI GeneCards UniProt Show fit	protein arginine methyltransferase 1
chr18_-_36129305 Show fit	18.52	ENST00000269187.10 ENST00000590986.5 ENST00000440549.6	SLC39A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 6
chr7_+_55365317 Show fit	18.26	ENST00000254770.3	LANCL2 Ensembl NCBI GeneCards UniProt Show fit	LanC like 2
chr1_+_220094086 Show fit	18.01	ENST00000366922.3	IARS2 Ensembl NCBI GeneCards UniProt Show fit	isoleucyl-tRNA synthetase 2, mitochondrial
chr2_-_70293438 Show fit	17.63	ENST00000482975.6 ENST00000438261.5	SNRPG Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide G
chr2_+_130342850 Show fit	17.28	ENST00000409935.5 ENST00000259239.8 ENST00000409649.5 ENST00000428740.5	IMP4 Ensembl NCBI GeneCards UniProt Show fit	IMP U3 small nucleolar ribonucleoprotein 4
chr1_-_23344314 Show fit	16.36	ENST00000374612.5 ENST00000675048.1 ENST00000478691.5	HNRNPR Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein R
chrX_+_71283186 Show fit	16.21	ENST00000535149.5	NONO Ensembl NCBI GeneCards UniProt Show fit	non-POU domain containing octamer binding
chr15_+_59105205 Show fit	15.86	ENST00000621385.1	CCNB2 Ensembl NCBI GeneCards UniProt Show fit	cyclin B2
chr22_+_23966880 Show fit	15.52	ENST00000215770.6	DDTL Ensembl NCBI GeneCards UniProt Show fit	D-dopachrome tautomerase like
chrX_+_152831054 Show fit	15.48	ENST00000370274.8	NSDHL Ensembl NCBI GeneCards UniProt Show fit	NAD(P) dependent steroid dehydrogenase-like
chr17_-_49708145 Show fit	15.47	ENST00000514907.5 ENST00000503334.5 ENST00000508520.5	SLC35B1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 member B1
chr1_-_167935987 Show fit	15.34	ENST00000367846.8	MPC2 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial pyruvate carrier 2
chrX_-_16869840 Show fit	15.29	ENST00000380084.8	RBBP7 Ensembl NCBI GeneCards UniProt Show fit	RB binding protein 7, chromatin remodeling factor
chr1_+_62437015 Show fit	14.96	ENST00000339950.5	USP1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 1
chr7_-_138002017 Show fit	14.89	ENST00000452463.5 ENST00000456390.5 ENST00000330387.11	CREB3L2 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 3 like 2
chr2_+_65227792 Show fit	14.81	ENST00000260641.10 ENST00000377982.8	ACTR2 Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2
chr22_-_41946688 Show fit	14.71	ENST00000404067.5 ENST00000402338.5	CENPM Ensembl NCBI GeneCards UniProt Show fit	centromere protein M
chr7_-_100101333 Show fit	14.58	ENST00000303887.10	MCM7 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 7
chr2_-_70293675 Show fit	14.56	ENST00000454893.1 ENST00000272348.7	SNRPG Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide G
chr1_-_23344259 Show fit	14.26	ENST00000476451.2 ENST00000302271.11 ENST00000606561.5 ENST00000374616.7	HNRNPR Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein R
chr19_-_45691771 Show fit	13.85	ENST00000588599.5 ENST00000585392.2 ENST00000590212.1 ENST00000587367.5 ENST00000391932.7 ENST00000342669.8	SNRPD2 Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein D2 polypeptide
chr12_-_56300299 Show fit	13.76	ENST00000552688.5 ENST00000548041.5 ENST00000551137.5 ENST00000551968.5 ENST00000351328.8 ENST00000542324.6 ENST00000546930.5 ENST00000549221.5 ENST00000550159.5 ENST00000550734.5	CS Ensembl NCBI GeneCards UniProt Show fit	citrate synthase
chr1_+_62436297 Show fit	13.54	ENST00000452143.5 ENST00000442679.5 ENST00000371146.5	USP1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 1
chr3_+_158801926 Show fit	13.25	ENST00000622669.4 ENST00000392813.8 ENST00000415822.8 ENST00000651862.1 ENST00000264266.12	MFSD1 Ensembl NCBI GeneCards UniProt Show fit	major facilitator superfamily domain containing 1
chrX_+_152830967 Show fit	13.13	ENST00000440023.5	NSDHL Ensembl NCBI GeneCards UniProt Show fit	NAD(P) dependent steroid dehydrogenase-like
chr19_-_14136553 Show fit	12.97	ENST00000592798.5 ENST00000474890.1 ENST00000263382.8	ASF1B Ensembl NCBI GeneCards UniProt Show fit	anti-silencing function 1B histone chaperone
chr12_-_56300358 Show fit	12.84	ENST00000550655.5 ENST00000548567.5 ENST00000551430.6	CS Ensembl NCBI GeneCards UniProt Show fit	citrate synthase
chr17_+_28319149 Show fit	12.75	ENST00000226230.8 ENST00000583381.5 ENST00000582113.1 ENST00000582384.1	TMEM97 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 97
chr4_+_146175702 Show fit	12.64	ENST00000296581.11 ENST00000649747.1 ENST00000502781.5	LSM6 Ensembl NCBI GeneCards UniProt Show fit	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr12_-_6851245 Show fit	12.50	ENST00000540683.1 ENST00000229265.10 ENST00000535406.5 ENST00000422785.7 ENST00000538862.7	CDCA3 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle associated 3
chr17_+_59619605 Show fit	12.39	ENST00000621829.4	CLTC Ensembl NCBI GeneCards UniProt Show fit	clathrin heavy chain
chr11_-_66289125 Show fit	12.33	ENST00000471387.6 ENST00000376901.9 ENST00000359461.10	YIF1A Ensembl NCBI GeneCards UniProt Show fit	Yip1 interacting factor homolog A, membrane trafficking protein
chr1_-_16978276 Show fit	12.25	ENST00000375534.7	MFAP2 Ensembl NCBI GeneCards UniProt Show fit	microfibril associated protein 2
chr15_-_37101205 Show fit	12.15	ENST00000338564.9 ENST00000558313.5 ENST00000340545.9	MEIS2 Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 2
chr7_+_77798832 Show fit	12.03	ENST00000415251.6 ENST00000275575.11	PHTF2 Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr11_+_68030896 Show fit	11.95	ENST00000525628.1	NDUFS8 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S8
chrX_+_155216452 Show fit	11.93	ENST00000286428.7	VBP1 Ensembl NCBI GeneCards UniProt Show fit	VHL binding protein 1
chr15_+_80059635 Show fit	11.68	ENST00000559157.5	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr1_-_150697128 Show fit	11.61	ENST00000427665.1 ENST00000271732.8	GOLPH3L Ensembl NCBI GeneCards UniProt Show fit	golgi phosphoprotein 3 like
chr1_-_94925759 Show fit	11.48	ENST00000415017.1 ENST00000545882.5	CNN3 Ensembl NCBI GeneCards UniProt Show fit	calponin 3
chr11_+_63986821 Show fit	11.47	ENST00000543988.1	OTUB1 Ensembl NCBI GeneCards UniProt Show fit	OTU deubiquitinase, ubiquitin aldehyde binding 1
chr7_-_87220567 Show fit	11.41	ENST00000433078.5	TMEM243 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 243
chr2_+_130343137 Show fit	11.30	ENST00000452955.1	IMP4 Ensembl NCBI GeneCards UniProt Show fit	IMP U3 small nucleolar ribonucleoprotein 4
chr20_-_50153637 Show fit	11.22	ENST00000341698.2 ENST00000371652.9 ENST00000371650.9	PEDS1-UBE2V1 Ensembl NCBI GeneCards UniProt Show fit PEDS1 Ensembl NCBI GeneCards UniProt Show fit	PEDS1-UBE2V1 readthrough plasmanylethanolamine desaturase 1
chr6_+_30717433 Show fit	10.93	ENST00000681435.1	TUBB Ensembl NCBI GeneCards UniProt Show fit	tubulin beta class I
chr5_+_151771943 Show fit	10.58	ENST00000520177.6 ENST00000678854.1 ENST00000520006.2 ENST00000677105.1 ENST00000678101.1 ENST00000678910.1 ENST00000356245.8 ENST00000678646.1 ENST00000677433.1 ENST00000677369.1 ENST00000677284.1 ENST00000678564.1	G3BP1 Ensembl NCBI GeneCards UniProt Show fit	G3BP stress granule assembly factor 1
chr2_+_65228122 Show fit	10.51	ENST00000542850.2	ACTR2 Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2
chr4_+_165327659 Show fit	10.41	ENST00000507013.5 ENST00000261507.11 ENST00000393766.6 ENST00000504317.1	MSMO1 Ensembl NCBI GeneCards UniProt Show fit	methylsterol monooxygenase 1
chr3_+_138621225 Show fit	10.40	ENST00000479848.1	FAIM Ensembl NCBI GeneCards UniProt Show fit	Fas apoptotic inhibitory molecule
chr17_-_49707900 Show fit	10.32	ENST00000511763.6 ENST00000515850.6 ENST00000649906.1 ENST00000240333.12	SLC35B1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 member B1
chr7_+_6009222 Show fit	10.22	ENST00000400479.6 ENST00000223029.8 ENST00000395236.2	AIMP2 Ensembl NCBI GeneCards UniProt Show fit	aminoacyl tRNA synthetase complex interacting multifunctional protein 2
chr7_-_44573895 Show fit	10.15	ENST00000258772.10 ENST00000431640.5	DDX56 Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 56
chrX_+_71283577 Show fit	9.97	ENST00000420903.6 ENST00000373856.8 ENST00000678437.1 ENST00000678830.1 ENST00000677879.1 ENST00000373841.5 ENST00000276079.13 ENST00000676797.1 ENST00000678660.1 ENST00000678231.1 ENST00000677612.1 ENST00000413858.5 ENST00000450092.6	NONO Ensembl NCBI GeneCards UniProt Show fit	non-POU domain containing octamer binding
chr7_-_149028651 Show fit	9.94	ENST00000286091.9	PDIA4 Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 4
chr7_+_77798750 Show fit	9.78	ENST00000416283.6 ENST00000422959.6 ENST00000307305.12 ENST00000424760.5	PHTF2 Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr15_+_80059568 Show fit	9.75	ENST00000613266.4 ENST00000561060.5	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr4_-_142305935 Show fit	9.70	ENST00000511838.5	INPP4B Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-4-phosphatase type II B
chr6_+_30720335 Show fit	9.70	ENST00000327892.13	TUBB Ensembl NCBI GeneCards UniProt Show fit	tubulin beta class I
chr5_+_146447304 Show fit	9.70	ENST00000296702.9 ENST00000394421.7 ENST00000679501.2	TCERG1 Ensembl NCBI GeneCards UniProt Show fit	transcription elongation regulator 1
chr12_+_56224318 Show fit	9.58	ENST00000267023.9 ENST00000380198.6 ENST00000341463.5	NABP2 Ensembl NCBI GeneCards UniProt Show fit	nucleic acid binding protein 2
chr16_+_69424610 Show fit	9.56	ENST00000307892.13	CYB5B Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 type B
chr6_+_159790448 Show fit	9.39	ENST00000367034.5	MRPL18 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L18
chr19_+_12938598 Show fit	9.38	ENST00000586760.2 ENST00000316448.10 ENST00000588454.6	CALR Ensembl NCBI GeneCards UniProt Show fit	calreticulin
chrX_-_77895414 Show fit	9.37	ENST00000618282.5 ENST00000373336.3	MAGT1 Ensembl NCBI GeneCards UniProt Show fit	magnesium transporter 1
chr1_+_42682388 Show fit	9.28	ENST00000321358.12 ENST00000332220.10	YBX1 Ensembl NCBI GeneCards UniProt Show fit	Y-box binding protein 1
chr5_+_151771884 Show fit	9.12	ENST00000627077.2 ENST00000678976.1 ENST00000677408.1 ENST00000678070.1 ENST00000678964.1 ENST00000678925.1 ENST00000394123.7 ENST00000522761.6 ENST00000676827.1	G3BP1 Ensembl NCBI GeneCards UniProt Show fit	G3BP stress granule assembly factor 1
chr17_-_82022858 Show fit	9.03	ENST00000584600.5 ENST00000392359.8 ENST00000584347.1 ENST00000580435.5 ENST00000306704.10	CENPX Ensembl NCBI GeneCards UniProt Show fit	centromere protein X
chr1_-_35193135 Show fit	9.00	ENST00000357214.6	SFPQ Ensembl NCBI GeneCards UniProt Show fit	splicing factor proline and glutamine rich
chr12_-_48682158 Show fit	8.97	ENST00000553086.5 ENST00000548304.1 ENST00000550347.5 ENST00000420613.7 ENST00000550931.5 ENST00000550870.1	KANSL2 Ensembl NCBI GeneCards UniProt Show fit	KAT8 regulatory NSL complex subunit 2
chr7_-_149028452 Show fit	8.89	ENST00000413966.1 ENST00000652332.1	PDIA4 Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 4
chr1_-_154974361 Show fit	8.86	ENST00000368453.8 ENST00000368450.5	SHC1 Ensembl NCBI GeneCards UniProt Show fit	SHC adaptor protein 1
chr10_-_1048879 Show fit	8.83	ENST00000429642.2	IDI1 Ensembl NCBI GeneCards UniProt Show fit	isopentenyl-diphosphate delta isomerase 1
chr3_-_33440343 Show fit	8.82	ENST00000283629.8	UBP1 Ensembl NCBI GeneCards UniProt Show fit	upstream binding protein 1
chr13_-_49792675 Show fit	8.77	ENST00000261667.8	KPNA3 Ensembl NCBI GeneCards UniProt Show fit	karyopherin subunit alpha 3
chr7_+_12687625 Show fit	8.72	ENST00000651779.1 ENST00000404894.1	ARL4A Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 4A
chr10_-_1049110 Show fit	8.64	ENST00000381344.8	IDI1 Ensembl NCBI GeneCards UniProt Show fit	isopentenyl-diphosphate delta isomerase 1
chr19_+_17309531 Show fit	8.59	ENST00000359866.9	DDA1 Ensembl NCBI GeneCards UniProt Show fit	DET1 and DDB1 associated 1
chr10_-_124418912 Show fit	8.53	ENST00000368845.6 ENST00000539214.5	OAT Ensembl NCBI GeneCards UniProt Show fit	ornithine aminotransferase
chr3_+_138621207 Show fit	8.39	ENST00000464668.5	FAIM Ensembl NCBI GeneCards UniProt Show fit	Fas apoptotic inhibitory molecule
chr6_+_113857333 Show fit	8.34	ENST00000612661.2	MARCKS Ensembl NCBI GeneCards UniProt Show fit	myristoylated alanine rich protein kinase C substrate
chr19_+_44891206 Show fit	8.33	ENST00000405636.6 ENST00000252487.9 ENST00000592434.5 ENST00000589649.1 ENST00000426677.7	TOMM40 Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 40
chrX_-_15854743 Show fit	8.31	ENST00000450644.2	AP1S2 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit sigma 2
chr19_+_17267469 Show fit	8.18	ENST00000596335.5 ENST00000601436.5 ENST00000595632.5	BABAM1 Ensembl NCBI GeneCards UniProt Show fit	BRISC and BRCA1 A complex member 1
chr2_-_86195400 Show fit	8.12	ENST00000442664.6 ENST00000409051.6 ENST00000410111.8 ENST00000620815.4 ENST00000449247.6	IMMT Ensembl NCBI GeneCards UniProt Show fit	inner membrane mitochondrial protein
chr9_-_35072588 Show fit	8.07	ENST00000677257.1 ENST00000679862.1 ENST00000679902.1 ENST00000358901.11 ENST00000681335.1 ENST00000681386.1 ENST00000679647.1 ENST00000448530.6	VCP Ensembl NCBI GeneCards UniProt Show fit	valosin containing protein
chr5_+_55307979 Show fit	7.96	ENST00000230640.10	MTREX Ensembl NCBI GeneCards UniProt Show fit	Mtr4 exosome RNA helicase
chr3_-_125055987 Show fit	7.93	ENST00000311127.9	HEG1 Ensembl NCBI GeneCards UniProt Show fit	heart development protein with EGF like domains 1
chr6_-_31862809 Show fit	7.84	ENST00000375631.5	NEU1 Ensembl NCBI GeneCards UniProt Show fit	neuraminidase 1
chr18_-_74291924 Show fit	7.81	ENST00000494131.6 ENST00000340533.9 ENST00000397914.4	CYB5A Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 type A
chr15_-_77071032 Show fit	7.80	ENST00000559494.1	TSPAN3 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 3
chr14_+_23321543 Show fit	7.80	ENST00000556821.5	PABPN1 Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein nuclear 1
chr19_+_19192911 Show fit	7.79	ENST00000392324.8	RFXANK Ensembl NCBI GeneCards UniProt Show fit	regulatory factor X associated ankyrin containing protein
chr11_+_9575496 Show fit	7.79	ENST00000681684.1	WEE1 Ensembl NCBI GeneCards UniProt Show fit	WEE1 G2 checkpoint kinase
chr19_+_19192763 Show fit	7.76	ENST00000407360.7 ENST00000540981.5	RFXANK Ensembl NCBI GeneCards UniProt Show fit	regulatory factor X associated ankyrin containing protein
chr16_+_69311339 Show fit	7.71	ENST00000254950.13	VPS4A Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 4 homolog A
chr14_-_34462223 Show fit	7.63	ENST00000298130.5	SPTSSA Ensembl NCBI GeneCards UniProt Show fit	serine palmitoyltransferase small subunit A
chr16_-_10942443 Show fit	7.54	ENST00000570440.2 ENST00000331808.5	DEXI Ensembl NCBI GeneCards UniProt Show fit	Dexi homolog
chr5_+_160009113 Show fit	7.49	ENST00000522793.5 ENST00000682719.1 ENST00000684137.1 ENST00000683219.1 ENST00000684018.1 ENST00000231238.10 ENST00000682131.1	TTC1 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 1
chr15_+_80059651 Show fit	7.33	ENST00000561012.5 ENST00000261749.11 ENST00000564367.5 ENST00000558494.5	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr12_+_21501780 Show fit	7.22	ENST00000229314.10 ENST00000542038.5 ENST00000540141.5 ENST00000631252.2	GOLT1B Ensembl NCBI GeneCards UniProt Show fit	golgi transport 1B
chr17_+_47649899 Show fit	7.18	ENST00000290158.9	KPNB1 Ensembl NCBI GeneCards UniProt Show fit	karyopherin subunit beta 1
chr3_-_165837412 Show fit	7.11	ENST00000479451.5 ENST00000488954.1 ENST00000264381.8	BCHE Ensembl NCBI GeneCards UniProt Show fit	butyrylcholinesterase
chr8_-_25458389 Show fit	7.11	ENST00000221200.9	KCTD9 Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 9
chr20_+_37693948 Show fit	7.02	ENST00000405275.6 ENST00000621317.4	CTNNBL1 Ensembl NCBI GeneCards UniProt Show fit	catenin beta like 1
chr1_+_224183197 Show fit	6.98	ENST00000323699.9	DEGS1 Ensembl NCBI GeneCards UniProt Show fit	delta 4-desaturase, sphingolipid 1
chr17_+_8288637 Show fit	6.97	ENST00000407006.8 ENST00000226105.11 ENST00000580434.5 ENST00000439238.3	RANGRF Ensembl NCBI GeneCards UniProt Show fit	RAN guanine nucleotide release factor
chr11_+_57712574 Show fit	6.93	ENST00000278422.9 ENST00000378312.8	TMX2 Ensembl NCBI GeneCards UniProt Show fit	thioredoxin related transmembrane protein 2
chr16_+_69424634 Show fit	6.92	ENST00000515314.6 ENST00000561792.6 ENST00000568237.1	CYB5B Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 type B
chr22_-_42090743 Show fit	6.88	ENST00000498737.8 ENST00000617763.1	NDUFA6 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit A6
chr20_+_37694022 Show fit	6.81	ENST00000361383.11 ENST00000447935.3 ENST00000628103.2	CTNNBL1 Ensembl NCBI GeneCards UniProt Show fit	catenin beta like 1
chr1_-_20661356 Show fit	6.79	ENST00000602624.7 ENST00000464364.1	DDOST Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr14_-_74493322 Show fit	6.78	ENST00000553490.5 ENST00000557510.5	NPC2 Ensembl NCBI GeneCards UniProt Show fit	NPC intracellular cholesterol transporter 2
chr14_-_74493275 Show fit	6.72	ENST00000541064.5	NPC2 Ensembl NCBI GeneCards UniProt Show fit	NPC intracellular cholesterol transporter 2
chr15_+_89088417 Show fit	6.69	ENST00000569550.5 ENST00000565066.5 ENST00000565973.5 ENST00000352732.10	ABHD2 Ensembl NCBI GeneCards UniProt Show fit	abhydrolase domain containing 2, acylglycerol lipase
chr12_+_2890870 Show fit	6.63	ENST00000544943.5 ENST00000448120.7	TULP3 Ensembl NCBI GeneCards UniProt Show fit	TUB like protein 3
chr1_+_167936559 Show fit	6.61	ENST00000432587.6 ENST00000367843.7 ENST00000312263.10	DCAF6 Ensembl NCBI GeneCards UniProt Show fit	DDB1 and CUL4 associated factor 6
chr12_+_98515573 Show fit	6.51	ENST00000556029.6 ENST00000343315.9 ENST00000266732.8 ENST00000393053.6	TMPO Ensembl NCBI GeneCards UniProt Show fit	thymopoietin
chr11_+_65181194 Show fit	6.48	ENST00000533820.5	CAPN1 Ensembl NCBI GeneCards UniProt Show fit	calpain 1
chr9_-_35072561 Show fit	6.48	ENST00000678650.1	VCP Ensembl NCBI GeneCards UniProt Show fit	valosin containing protein
chr7_-_24980148 Show fit	6.39	ENST00000313367.7	OSBPL3 Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein like 3
chr10_-_131981912 Show fit	6.37	ENST00000540159.3	BNIP3 Ensembl NCBI GeneCards UniProt Show fit	BCL2 interacting protein 3
chr7_+_44796677 Show fit	6.28	ENST00000451562.5 ENST00000489459.5 ENST00000355968.10 ENST00000677107.1 ENST00000468812.6 ENST00000620047.5	PPIA Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase A
chr19_+_38930916 Show fit	6.22	ENST00000308018.9 ENST00000407800.2 ENST00000402029.3	MRPS12 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S12
chr17_+_81683963 Show fit	6.21	ENST00000676462.1 ENST00000679336.1 ENST00000678196.1 ENST00000677243.1 ENST00000677044.1 ENST00000677109.1 ENST00000677484.1 ENST00000678105.1 ENST00000677209.1 ENST00000329138.9 ENST00000677225.1 ENST00000678866.1 ENST00000676729.1 ENST00000572392.2 ENST00000577012.1	HGS Ensembl NCBI GeneCards UniProt Show fit	hepatocyte growth factor-regulated tyrosine kinase substrate
chr2_-_187554351 Show fit	6.21	ENST00000437725.5 ENST00000409676.5 ENST00000233156.9 ENST00000339091.8 ENST00000420747.1	TFPI Ensembl NCBI GeneCards UniProt Show fit	tissue factor pathway inhibitor
chr2_-_200963633 Show fit	6.18	ENST00000234296.7	ORC2 Ensembl NCBI GeneCards UniProt Show fit	origin recognition complex subunit 2
chr11_+_68030644 Show fit	6.17	ENST00000453471.6 ENST00000313468.10 ENST00000528492.1 ENST00000526339.5 ENST00000525419.5	NDUFS8 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S8
chr15_+_41231219 Show fit	6.17	ENST00000334660.10 ENST00000560397.5	CHP1 Ensembl NCBI GeneCards UniProt Show fit	calcineurin like EF-hand protein 1
chr2_-_55049184 Show fit	6.12	ENST00000357376.7	RTN4 Ensembl NCBI GeneCards UniProt Show fit	reticulon 4
chrX_-_77895546 Show fit	6.10	ENST00000358075.11	MAGT1 Ensembl NCBI GeneCards UniProt Show fit	magnesium transporter 1
chr6_-_33418077 Show fit	6.09	ENST00000488478.5	CUTA Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog
chr19_-_47113756 Show fit	6.07	ENST00000253048.10	ZC3H4 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 4
chr14_-_74493291 Show fit	6.05	ENST00000238633.6 ENST00000555619.6 ENST00000434013.6	NPC2 Ensembl NCBI GeneCards UniProt Show fit	NPC intracellular cholesterol transporter 2
chr1_-_20661518 Show fit	6.02	ENST00000415136.6	DDOST Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr4_-_142305826 Show fit	5.94	ENST00000514525.1	INPP4B Ensembl NCBI GeneCards UniProt Show fit	inositol polyphosphate-4-phosphatase type II B
chr10_+_84139491 Show fit	5.86	ENST00000372134.6	GHITM Ensembl NCBI GeneCards UniProt Show fit	growth hormone inducible transmembrane protein
chr5_+_71587351 Show fit	5.79	ENST00000683339.1	MCCC2 Ensembl NCBI GeneCards UniProt Show fit	methylcrotonoyl-CoA carboxylase 2
chr9_+_12693327 Show fit	5.77	ENST00000388918.10	TYRP1 Ensembl NCBI GeneCards UniProt Show fit	tyrosinase related protein 1
chr5_+_71587321 Show fit	5.66	ENST00000683429.1 ENST00000509358.7 ENST00000340941.11	MCCC2 Ensembl NCBI GeneCards UniProt Show fit	methylcrotonoyl-CoA carboxylase 2
chr1_-_94927079 Show fit	5.57	ENST00000370206.9 ENST00000394202.8	CNN3 Ensembl NCBI GeneCards UniProt Show fit	calponin 3
chr19_-_13116649 Show fit	5.55	ENST00000437766.5 ENST00000221504.12	TRMT1 Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 1
chr16_+_68245304 Show fit	5.37	ENST00000413021.2 ENST00000565744.5 ENST00000564827.6 ENST00000566188.5 ENST00000444212.2 ENST00000219345.10 ENST00000568082.1	PLA2G15 Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group XV
chr10_-_131982006 Show fit	5.36	ENST00000368636.8	BNIP3 Ensembl NCBI GeneCards UniProt Show fit	BCL2 interacting protein 3
chrX_+_152830991 Show fit	5.24	ENST00000432467.1	NSDHL Ensembl NCBI GeneCards UniProt Show fit	NAD(P) dependent steroid dehydrogenase-like
chr3_-_100401028 Show fit	5.18	ENST00000284320.6	TOMM70 Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 70
chr9_-_134068012 Show fit	5.16	ENST00000303407.12	BRD3 Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 3
chr6_+_20401864 Show fit	5.10	ENST00000346618.8 ENST00000613242.4	E2F3 Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 3
chr3_-_195811889 Show fit	5.10	ENST00000475231.5	MUC4 Ensembl NCBI GeneCards UniProt Show fit	mucin 4, cell surface associated
chr7_-_44848021 Show fit	5.05	ENST00000349299.7 ENST00000521529.5 ENST00000350771.7 ENST00000222690.10 ENST00000381124.9 ENST00000437072.5 ENST00000446531.1 ENST00000308153.9	H2AZ2 Ensembl NCBI GeneCards UniProt Show fit	H2A.Z variant histone 2
chr10_-_102120318 Show fit	5.03	ENST00000673968.1	LDB1 Ensembl NCBI GeneCards UniProt Show fit	LIM domain binding 1
chr19_-_6424802 Show fit	5.01	ENST00000600480.2	KHSRP Ensembl NCBI GeneCards UniProt Show fit	KH-type splicing regulatory protein
chr17_-_7263959 Show fit	4.92	ENST00000571932.2	CLDN7 Ensembl NCBI GeneCards UniProt Show fit	claudin 7
chr9_+_137241277 Show fit	4.91	ENST00000340384.5	TUBB4B Ensembl NCBI GeneCards UniProt Show fit	tubulin beta 4B class IVb
chr10_-_125816596 Show fit	4.87	ENST00000368786.5	UROS Ensembl NCBI GeneCards UniProt Show fit	uroporphyrinogen III synthase
chr7_-_100119323 Show fit	4.83	ENST00000523306.5 ENST00000344095.8 ENST00000417349.5 ENST00000493322.5 ENST00000520135.5 ENST00000460673.2 ENST00000453269.7 ENST00000452041.5 ENST00000452438.6 ENST00000451699.5	TAF6 Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 6
chr19_-_13116719 Show fit	4.81	ENST00000588229.1 ENST00000357720.9	TRMT1 Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 1
chr17_+_48892761 Show fit	4.79	ENST00000355938.9 ENST00000393366.7 ENST00000503641.5 ENST00000514808.5 ENST00000506855.1	ATP5MC1 Ensembl NCBI GeneCards UniProt Show fit	ATP synthase membrane subunit c locus 1
chr22_-_30564889 Show fit	4.73	ENST00000401975.5 ENST00000428682.5 ENST00000423299.5	GAL3ST1 Ensembl NCBI GeneCards UniProt Show fit	galactose-3-O-sulfotransferase 1
chr13_-_41019289 Show fit	4.70	ENST00000239882.7	ELF1 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 1
chr6_+_167291329 Show fit	4.62	ENST00000366829.2	UNC93A Ensembl NCBI GeneCards UniProt Show fit	unc-93 homolog A
chr4_+_168092530 Show fit	4.57	ENST00000359299.8	ANXA10 Ensembl NCBI GeneCards UniProt Show fit	annexin A10
chr8_+_119416427 Show fit	4.55	ENST00000259526.4	CCN3 Ensembl NCBI GeneCards UniProt Show fit	cellular communication network factor 3
chr4_-_39977836 Show fit	4.50	ENST00000303538.13 ENST00000503396.5	PDS5A Ensembl NCBI GeneCards UniProt Show fit	PDS5 cohesin associated factor A
chr12_-_56645955 Show fit	4.49	ENST00000552959.5 ENST00000551020.5 ENST00000553007.2 ENST00000262030.8	ATP5F1B Ensembl NCBI GeneCards UniProt Show fit	ATP synthase F1 subunit beta
chr10_-_131981948 Show fit	4.49	ENST00000633835.1	BNIP3 Ensembl NCBI GeneCards UniProt Show fit	BCL2 interacting protein 3
chr11_+_95790459 Show fit	4.39	ENST00000325486.9 ENST00000325542.10 ENST00000544522.5 ENST00000541365.5	CEP57 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 57
chr17_-_7242156 Show fit	4.30	ENST00000571129.5 ENST00000571253.1 ENST00000573928.1 ENST00000302386.10	GABARAP Ensembl NCBI GeneCards UniProt Show fit	GABA type A receptor-associated protein
chr22_-_32255344 Show fit	4.23	ENST00000266086.6	SLC5A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 5 member 4
chr1_+_151166001 Show fit	4.22	ENST00000368902.1 ENST00000368905.9	SCNM1 Ensembl NCBI GeneCards UniProt Show fit	sodium channel modifier 1
chr5_-_83673544 Show fit	4.16	ENST00000503117.1 ENST00000510978.5	HAPLN1 Ensembl NCBI GeneCards UniProt Show fit	hyaluronan and proteoglycan link protein 1
chr1_-_167553745 Show fit	4.14	ENST00000370509.5	CREG1 Ensembl NCBI GeneCards UniProt Show fit	cellular repressor of E1A stimulated genes 1
chr19_-_14529193 Show fit	4.06	ENST00000596853.6 ENST00000676515.1 ENST00000678338.1 ENST00000595992.6 ENST00000677848.1 ENST00000677762.1 ENST00000678009.1 ENST00000596075.2 ENST00000601533.6 ENST00000396969.8 ENST00000598692.2 ENST00000678098.1	DNAJB1 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B1
chr15_-_43510571 Show fit	4.01	ENST00000263801.7	TP53BP1 Ensembl NCBI GeneCards UniProt Show fit	tumor protein p53 binding protein 1
chr10_-_5813387 Show fit	3.97	ENST00000456041.5 ENST00000380181.7 ENST00000418688.5 ENST00000609712.1 ENST00000380191.9	GDI2 Ensembl NCBI GeneCards UniProt Show fit	GDP dissociation inhibitor 2
chr13_+_102596972 Show fit	3.96	ENST00000376052.5 ENST00000376065.8 ENST00000652308.1 ENST00000651544.1	TPP2 Ensembl NCBI GeneCards UniProt Show fit	tripeptidyl peptidase 2
chr19_+_41264345 Show fit	3.86	ENST00000378215.8 ENST00000392006.8 ENST00000617774.1 ENST00000602130.5 ENST00000617305.4	HNRNPUL1 Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein U like 1
chr16_-_18801424 Show fit	3.86	ENST00000546206.6 ENST00000562819.5 ENST00000304414.12 ENST00000562234.2 ENST00000567078.2	ARL6IP1 Ensembl NCBI GeneCards UniProt Show fit ENSG00000260342.2 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 6 interacting protein 1 novel protein
chr10_-_125816510 Show fit	3.84	ENST00000650587.1	UROS Ensembl NCBI GeneCards UniProt Show fit	uroporphyrinogen III synthase
chr11_-_123062022 Show fit	3.75	ENST00000532182.5 ENST00000524590.5 ENST00000528292.5 ENST00000533540.5 ENST00000534624.6 ENST00000525463.5	HSPA8 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family A (Hsp70) member 8
chr19_+_10718047 Show fit	3.69	ENST00000585892.5 ENST00000355667.11 ENST00000389253.9 ENST00000359692.10	DNM2 Ensembl NCBI GeneCards UniProt Show fit	dynamin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.9	50.8	GO:0009786	regulation of asymmetric cell division(GO:0009786)
8.6	25.8	GO:0072334	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
8.4	25.3	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
7.8	70.3	GO:0031536	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536)
6.6	46.2	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
6.2	12.4	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
6.1	18.3	GO:1901421	positive regulation of response to alcohol(GO:1901421)
4.8	14.5	GO:1903004	flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
4.1	41.2	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
3.9	19.6	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
3.3	9.9	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
3.3	26.2	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
3.1	9.4	GO:0035928	rRNA import into mitochondrion(GO:0035928)
2.9	8.8	GO:1902594	viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
2.6	33.8	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
2.6	7.7	GO:1903774	mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) positive regulation of viral budding via host ESCRT complex(GO:1903774)
2.4	7.1	GO:0014016	neuroblast differentiation(GO:0014016)
2.3	9.4	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501)
2.3	7.0	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
2.3	16.2	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637) cellular response to cobalt ion(GO:0071279)
2.2	8.7	GO:0071418	cellular response to amine stimulus(GO:0071418)
2.1	6.4	GO:0060434	bronchus morphogenesis(GO:0060434)
2.1	10.5	GO:0031291	Ran protein signal transduction(GO:0031291)
2.1	18.5	GO:0071578	zinc II ion transmembrane import(GO:0071578)
2.0	10.2	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
1.9	5.7	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
1.9	13.0	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
1.8	27.3	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.8	28.5	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
1.8	12.3	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
1.7	15.5	GO:0015693	magnesium ion transport(GO:0015693)
1.7	28.8	GO:0000022	mitotic spindle elongation(GO:0000022)
1.5	9.0	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
1.4	7.2	GO:1902904	late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.4	13.0	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.4	18.0	GO:0006450	regulation of translational fidelity(GO:0006450)
1.3	35.5	GO:0061157	mRNA destabilization(GO:0061157)
1.3	3.9	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
1.2	33.9	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
1.2	11.6	GO:0048194	Golgi vesicle budding(GO:0048194)
1.1	39.0	GO:0034080	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.1	7.9	GO:0090269	fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
1.1	3.4	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.1	5.6	GO:0009240	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
1.1	3.3	GO:0072183	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
1.1	46.0	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
1.1	8.5	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.0	41.8	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.0	11.5	GO:0006552	leucine catabolic process(GO:0006552)
1.0	7.8	GO:0006689	ganglioside catabolic process(GO:0006689)
1.0	28.8	GO:0072662	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.9	17.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.9	45.4	GO:0006294	nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.9	6.2	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.8	3.1	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) lymphotoxin A production(GO:0032641) positive regulation of mast cell cytokine production(GO:0032765) lymphotoxin A biosynthetic process(GO:0042109)
0.8	3.1	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.7	3.6	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.7	11.9	GO:0007021	tubulin complex assembly(GO:0007021)
0.7	6.2	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.7	6.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.7	8.1	GO:0042407	cristae formation(GO:0042407)
0.7	25.6	GO:0019985	translesion synthesis(GO:0019985)
0.7	9.3	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.6	8.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.6	5.8	GO:0046459	short-chain fatty acid metabolic process(GO:0046459)
0.6	5.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.6	6.3	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.5	4.7	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.5	10.4	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.5	2.0	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.5	3.8	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.5	7.8	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.5	1.4	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.4	9.0	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.4	6.5	GO:0060056	mammary gland involution(GO:0060056)
0.4	10.4	GO:0030488	tRNA methylation(GO:0030488)
0.4	2.0	GO:0016584	nucleosome positioning(GO:0016584)
0.4	22.3	GO:0032508	DNA duplex unwinding(GO:0032508)
0.4	6.2	GO:1903543	positive regulation of exosomal secretion(GO:1903543)
0.4	9.6	GO:0070200	establishment of protein localization to telomere(GO:0070200)
0.4	2.6	GO:0044245	polysaccharide digestion(GO:0044245)
0.4	15.9	GO:0043029	T cell homeostasis(GO:0043029)
0.3	8.3	GO:0051764	actin crosslink formation(GO:0051764)
0.3	26.0	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.3	4.9	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.3	4.3	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3	6.7	GO:0048240	sperm capacitation(GO:0048240)
0.3	2.0	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.3	8.2	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.3	24.0	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3	11.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.3	14.6	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.3	5.4	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
0.2	12.8	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.2	2.2	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.2	1.9	GO:0007097	nuclear migration(GO:0007097)
0.2	4.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.2	15.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2	12.6	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.2	6.2	GO:0006270	DNA replication initiation(GO:0006270)
0.2	10.1	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.2	4.7	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2	14.9	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2	2.5	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2	2.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	14.9	GO:0045454	cell redox homeostasis(GO:0045454)
0.2	1.7	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2	5.2	GO:0071806	protein transmembrane transport(GO:0071806)
0.2	1.8	GO:0009642	response to light intensity(GO:0009642)
0.1	1.5	GO:0021814	cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1	8.9	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.1	12.2	GO:0045638	negative regulation of myeloid cell differentiation(GO:0045638)
0.1	3.3	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.1	4.9	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.1	2.6	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.1	1.4	GO:0045794	negative regulation of cell volume(GO:0045794)
0.1	16.5	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.1	7.8	GO:0016445	somatic diversification of immunoglobulins(GO:0016445)
0.1	8.2	GO:0042632	cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1	3.4	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	3.1	GO:0030517	negative regulation of axon extension(GO:0030517)
0.1	0.3	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965) dorsal/ventral axon guidance(GO:0033563) anterior/posterior axon guidance(GO:0033564)
0.1	6.2	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.1	19.9	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.1	1.9	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	1.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.8	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	2.8	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.1	0.4	GO:0061743	motor learning(GO:0061743)
0.1	13.2	GO:0006364	rRNA processing(GO:0006364)
0.1	8.8	GO:0019079	viral genome replication(GO:0019079)
0.1	1.7	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	3.5	GO:1902653	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0	6.9	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.0	1.6	GO:0033198	response to ATP(GO:0033198)
0.0	0.7	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	4.2	GO:0009615	response to virus(GO:0009615)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.1	28.6	GO:0034457	Mpp10 complex(GO:0034457)
5.7	22.7	GO:0071942	XPC complex(GO:0071942)
5.6	50.8	GO:0036449	microtubule minus-end(GO:0036449) meiotic spindle(GO:0072687)
5.5	27.3	GO:0097149	centralspindlin complex(GO:0097149)
5.4	87.2	GO:0034709	methylosome(GO:0034709)
3.9	35.2	GO:0042382	paraspeckles(GO:0042382)
3.6	14.5	GO:1990730	VCP-NSFL1C complex(GO:1990730)
3.0	9.0	GO:0071821	FANCM-MHF complex(GO:0071821)
2.6	36.8	GO:0070938	contractile ring(GO:0070938)
2.6	33.8	GO:0042555	MCM complex(GO:0042555)
2.4	9.8	GO:0070876	SOSS complex(GO:0070876)
2.4	70.3	GO:0005680	anaphase-promoting complex(GO:0005680)
2.4	28.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
2.2	8.9	GO:0070435	Shc-EGFR complex(GO:0070435)
2.1	6.2	GO:0033565	ESCRT-0 complex(GO:0033565)
2.1	6.2	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
2.0	24.0	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
1.9	7.6	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.8	21.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
1.7	11.9	GO:0016272	prefoldin complex(GO:0016272)
1.7	10.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.7	13.5	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
1.7	25.3	GO:0030478	actin cap(GO:0030478)
1.6	9.4	GO:0042824	MHC class I peptide loading complex(GO:0042824)
1.5	27.7	GO:0005641	nuclear envelope lumen(GO:0005641)
1.4	11.5	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
1.4	8.1	GO:0061617	MICOS complex(GO:0061617)
1.3	22.5	GO:0005662	DNA replication factor A complex(GO:0005662)
1.2	12.4	GO:0071439	clathrin complex(GO:0071439)
1.2	7.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
1.1	20.5	GO:0000974	Prp19 complex(GO:0000974)
1.1	56.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
1.0	12.6	GO:0005688	U6 snRNP(GO:0005688)
0.9	9.3	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.9	6.4	GO:0030991	intraciliary transport particle A(GO:0030991)
0.9	8.2	GO:0070552	BRISC complex(GO:0070552)
0.9	31.8	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.7	3.6	GO:0005726	perichromatin fibrils(GO:0005726)
0.7	16.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.7	16.6	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.7	15.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.6	15.3	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.6	3.1	GO:0032449	CBM complex(GO:0032449)
0.6	12.3	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.6	7.7	GO:0000815	ESCRT III complex(GO:0000815)
0.6	6.7	GO:0097524	sperm plasma membrane(GO:0097524)
0.6	8.3	GO:0043073	germ cell nucleus(GO:0043073)
0.6	3.3	GO:0070545	PeBoW complex(GO:0070545)
0.5	9.9	GO:0042405	nuclear inclusion body(GO:0042405)
0.5	6.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.4	7.7	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.4	18.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.3	24.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.3	4.3	GO:0097225	sperm midpiece(GO:0097225)
0.3	30.6	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.3	5.8	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3	23.9	GO:0005811	lipid particle(GO:0005811)
0.2	15.5	GO:0045171	intercellular bridge(GO:0045171)
0.2	15.4	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2	9.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2	6.2	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2	18.3	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.2	2.7	GO:0005869	dynactin complex(GO:0005869)
0.2	22.9	GO:0035578	azurophil granule lumen(GO:0035578)
0.2	28.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.2	2.0	GO:0042584	chromaffin granule membrane(GO:0042584)
0.2	16.2	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.2	2.0	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.2	3.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.2	4.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	11.8	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2	1.5	GO:0044327	dendritic spine head(GO:0044327)
0.2	16.2	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.1	1.0	GO:0042587	glycogen granule(GO:0042587)
0.1	18.9	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	7.8	GO:0035580	specific granule lumen(GO:0035580)
0.1	7.5	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1	1.7	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	19.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.1	8.8	GO:0043657	host(GO:0018995) host cell(GO:0043657)
0.1	1.9	GO:0030056	hemidesmosome(GO:0030056)
0.1	7.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	17.2	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.1	10.4	GO:0005796	Golgi lumen(GO:0005796)
0.1	5.6	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	0.5	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	1.6	GO:0000791	euchromatin(GO:0000791)
0.0	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	6.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	6.3	GO:0043209	myelin sheath(GO:0043209)
0.0	3.1	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	9.3	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	7.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	2.6	GO:0005903	brush border(GO:0005903)
0.0	2.1	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	5.5	GO:0000790	nuclear chromatin(GO:0000790)
0.0	1.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.4	GO:0005740	mitochondrial envelope(GO:0005740)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.3	33.9	GO:0047012	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
9.5	56.8	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
8.6	25.8	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
7.1	28.6	GO:0042134	rRNA primary transcript binding(GO:0042134)
6.9	41.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
6.5	25.9	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
4.5	22.7	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
3.8	26.6	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
3.1	15.6	GO:0052828	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
3.0	18.0	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
2.8	28.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.6	7.8	GO:0052794	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
2.5	7.6	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
2.4	14.5	GO:0035800	deubiquitinase activator activity(GO:0035800)
2.2	8.7	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
2.1	32.0	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
2.1	10.4	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
2.1	10.4	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
1.9	15.3	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
1.8	7.1	GO:0033265	acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
1.7	20.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
1.6	9.4	GO:0001849	complement component C1q binding(GO:0001849)
1.5	70.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
1.4	13.0	GO:0019784	NEDD8-specific protease activity(GO:0019784)
1.4	11.5	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
1.3	8.9	GO:0048408	epidermal growth factor binding(GO:0048408)
1.2	17.5	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.1	12.4	GO:0032051	clathrin light chain binding(GO:0032051)
1.1	9.0	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
1.1	3.4	GO:0015403	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.1	56.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
1.1	4.2	GO:0005412	glucose:sodium symporter activity(GO:0005412)
1.0	8.3	GO:0015288	porin activity(GO:0015288)
0.9	18.8	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.9	18.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.9	7.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.9	26.0	GO:0042288	MHC class I protein binding(GO:0042288)
0.9	24.0	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.8	4.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.8	3.8	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.7	14.9	GO:0035497	cAMP response element binding(GO:0035497)
0.7	9.4	GO:0008097	5S rRNA binding(GO:0008097)
0.7	2.7	GO:0070404	NADH binding(GO:0070404)
0.7	2.0	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.6	5.4	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.6	4.7	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.6	5.7	GO:0070569	uridylyltransferase activity(GO:0070569)
0.6	6.3	GO:0046790	virion binding(GO:0046790)
0.6	16.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.6	5.0	GO:0030274	LIM domain binding(GO:0030274)
0.5	2.6	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.5	7.7	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.5	2.6	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.5	28.8	GO:0031593	polyubiquitin binding(GO:0031593)
0.5	30.3	GO:0019894	kinesin binding(GO:0019894)
0.4	6.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.4	2.2	GO:0016882	cyclo-ligase activity(GO:0016882)
0.4	19.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.4	3.6	GO:0034056	estrogen response element binding(GO:0034056)
0.4	6.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.4	7.1	GO:0097602	cullin family protein binding(GO:0097602)
0.4	18.1	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.3	2.0	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3	5.2	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.3	9.7	GO:0070064	proline-rich region binding(GO:0070064)
0.3	35.5	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.3	35.2	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.3	8.5	GO:0008483	transaminase activity(GO:0008483)
0.3	18.9	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3	7.8	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3	18.1	GO:0005507	copper ion binding(GO:0005507)
0.3	15.9	GO:0015485	cholesterol binding(GO:0015485)
0.2	0.7	GO:0050815	phosphoserine binding(GO:0050815)
0.2	7.2	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.2	2.8	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2	1.4	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.2	4.3	GO:0050811	GABA receptor binding(GO:0050811)
0.2	10.4	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2	23.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2	5.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.2	11.9	GO:0070063	RNA polymerase binding(GO:0070063)
0.2	6.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2	0.8	GO:0019862	IgA binding(GO:0019862)
0.2	10.1	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2	1.4	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.2	1.7	GO:0015643	toxic substance binding(GO:0015643)
0.2	4.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	11.8	GO:0008565	protein transporter activity(GO:0008565)
0.1	6.2	GO:0004407	histone deacetylase activity(GO:0004407)
0.1	3.1	GO:0043422	protein kinase B binding(GO:0043422)
0.1	4.1	GO:0001671	ATPase activator activity(GO:0001671)
0.1	6.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	7.0	GO:0009055	electron carrier activity(GO:0009055)
0.1	0.3	GO:0005042	netrin receptor activity(GO:0005042)
0.1	4.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	4.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	31.8	GO:0005516	calmodulin binding(GO:0005516)
0.1	6.6	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	6.2	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	17.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	2.5	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	3.3	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	3.1	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	5.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	15.1	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1	1.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	7.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.3	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.1	15.5	GO:0016829	lyase activity(GO:0016829)
0.1	9.6	GO:0020037	heme binding(GO:0020037)
0.1	1.6	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	5.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	8.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.8	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.7	GO:0032183	SUMO binding(GO:0032183)
0.0	10.2	GO:0051020	GTPase binding(GO:0051020)
0.0	0.1	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	26.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
1.1	56.3	PID ATR PATHWAY	ATR signaling pathway
1.0	71.8	PID PLK1 PATHWAY	PLK1 signaling events
0.7	45.0	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.5	29.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.5	24.0	PID AURORA B PATHWAY	Aurora B signaling
0.4	9.6	PID FANCONI PATHWAY	Fanconi anemia pathway
0.3	8.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	10.5	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.2	3.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.2	15.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.2	15.8	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.2	4.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	15.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	12.4	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.2	3.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	3.4	PID ATM PATHWAY	ATM pathway
0.1	10.9	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	11.6	PID NOTCH PATHWAY	Notch signaling pathway
0.1	6.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	6.1	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	6.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	4.9	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	1.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	3.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	4.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	5.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	10.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	3.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	1.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	2.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	3.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.7	PID MYC PATHWAY	C-MYC pathway
0.0	0.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	70.3	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
2.4	28.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
2.3	33.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
2.1	32.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.5	22.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
1.3	21.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.2	49.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
1.1	10.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
1.1	23.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
1.1	18.0	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
1.0	6.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
1.0	18.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
1.0	61.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.8	11.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.8	20.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.8	15.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.8	6.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.7	10.5	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.7	8.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.7	9.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.7	12.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.7	15.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.7	13.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.6	9.9	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.6	12.8	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.5	11.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.5	8.9	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.5	10.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.4	37.3	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.4	11.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.4	24.0	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.4	7.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3	47.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.3	23.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	25.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.3	8.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.3	8.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	7.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	7.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2	12.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.2	7.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	2.6	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.2	3.4	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	14.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.2	3.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.2	2.8	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2	8.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	2.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	11.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	6.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	4.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	4.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	9.5	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	2.0	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	2.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	2.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	1.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	4.5	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	5.7	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.0	1.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases

Results for VSX1

Z-value: 1.27

Motif logo

Transcription factors associated with VSX1

Activity-expression correlation:

Activity profile of VSX1 motif

Sorted Z-values of VSX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of VSX1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: