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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for WT1_MTF1_ZBTB7B

Z-value: 3.94

Motif logo

Transcription factors associated with WT1_MTF1_ZBTB7B

Gene Symbol Gene ID Gene Info
ENSG00000184937.16 WT1
ENSG00000188786.10 MTF1
ENSG00000160685.13 ZBTB7B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB7Bhg38_v1_chr1_+_155002630_1550026890.752.8e-41Click!
WT1hg38_v1_chr11_-_32435360_324354190.371.1e-08Click!
MTF1hg38_v1_chr1_-_37859583_37859609-0.203.2e-03Click!

Activity profile of WT1_MTF1_ZBTB7B motif

Sorted Z-values of WT1_MTF1_ZBTB7B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of WT1_MTF1_ZBTB7B

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_176659 194.50 ENST00000320868.9
ENST00000397797.1
hemoglobin subunit alpha 1
chr11_-_134412234 171.29 ENST00000312527.9
beta-1,3-glucuronyltransferase 1
chr7_-_44325421 146.44 ENST00000395747.6
ENST00000347193.8
ENST00000346990.8
ENST00000258682.10
ENST00000353625.8
ENST00000421607.1
ENST00000424197.5
calcium/calmodulin dependent protein kinase II beta
chr16_+_58463663 145.45 ENST00000258187.9
NDRG family member 4
chr7_-_44325490 141.38 ENST00000350811.7
calcium/calmodulin dependent protein kinase II beta
chr11_-_134411854 138.23 ENST00000392580.5
beta-1,3-glucuronyltransferase 1
chr7_-_44325653 125.58 ENST00000440254.6
calcium/calmodulin dependent protein kinase II beta
chr19_+_708903 118.51 ENST00000338448.10
ENST00000264560.11
paralemmin
chr14_+_99684283 117.70 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr2_+_241702027 116.47 ENST00000313552.11
ENST00000406941.5
inhibitor of growth family member 5
chr11_-_2885728 115.54 ENST00000647251.1
ENST00000380725.2
ENST00000430149.3
ENST00000414822.8
ENST00000440480.8
cyclin dependent kinase inhibitor 1C
chr19_-_4065732 112.34 ENST00000601588.1
zinc finger and BTB domain containing 7A
chr12_-_54588516 110.58 ENST00000547431.5
protein phosphatase 1 regulatory inhibitor subunit 1A
chr16_+_172869 110.49 ENST00000251595.11
ENST00000397806.1
ENST00000484216.1
hemoglobin subunit alpha 2
chr8_+_143734133 109.45 ENST00000527139.7
ENST00000533004.5
IQ motif and ankyrin repeat containing 1
chr10_+_122461545 108.86 ENST00000368984.8
HtrA serine peptidase 1
chr11_-_236821 107.63 ENST00000529382.5
ENST00000528469.1
sirtuin 3
chrX_-_2500555 105.50 ENST00000381218.8
zinc finger BED-type containing 1
chr9_+_135087652 101.40 ENST00000371793.8
ENST00000539529.5
ENST00000392991.8
olfactomedin 1
chr15_+_80404320 100.78 ENST00000303329.9
ENST00000622346.4
aryl hydrocarbon receptor nuclear translocator 2
chr6_-_46491431 99.21 ENST00000371374.6
regulator of calcineurin 2
chr12_-_123972709 98.50 ENST00000545891.5
coiled-coil domain containing 92
chr8_-_19013649 98.00 ENST00000440756.4
pleckstrin and Sec7 domain containing 3
chrX_+_38561530 97.38 ENST00000378482.7
ENST00000286824.6
tetraspanin 7
chr14_-_21025490 97.03 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr9_+_127612257 95.47 ENST00000637173.2
ENST00000630492.2
ENST00000627871.2
ENST00000373302.8
ENST00000373299.5
ENST00000650920.1
ENST00000476182.3
syntaxin binding protein 1
chr10_-_116742584 94.90 ENST00000674205.1
heat shock protein family A (Hsp70) member 12A
chr1_+_169106681 94.69 ENST00000367815.9
ATPase Na+/K+ transporting subunit beta 1
chr17_+_79778135 93.81 ENST00000310942.9
ENST00000269399.5
chromobox 2
chr10_-_116742559 93.16 ENST00000674344.1
ENST00000369209.8
ENST00000674459.1
heat shock protein family A (Hsp70) member 12A
chr9_-_95317671 92.83 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FA complementation group C
chr9_+_130172343 92.37 ENST00000372398.6
neuronal calcium sensor 1
chr4_-_5888400 91.87 ENST00000397890.6
collapsin response mediator protein 1
chr18_-_5543960 90.54 ENST00000400111.8
erythrocyte membrane protein band 4.1 like 3
chr19_+_35030626 89.35 ENST00000638536.1
sodium voltage-gated channel beta subunit 1
chr19_+_35030438 89.01 ENST00000415950.5
ENST00000262631.11
sodium voltage-gated channel beta subunit 1
chr11_-_12009082 88.45 ENST00000396505.7
dickkopf WNT signaling pathway inhibitor 3
chr14_-_100587404 88.00 ENST00000554140.2
brain enriched guanylate kinase associated
chr9_+_127612222 86.40 ENST00000637953.1
ENST00000636962.2
syntaxin binding protein 1
chrX_-_13938378 86.33 ENST00000398361.7
glycoprotein M6B
chr19_+_35030711 86.09 ENST00000595652.5
sodium voltage-gated channel beta subunit 1
chr16_-_970847 85.65 ENST00000568897.5
lipase maturation factor 1
chr7_+_55887446 84.50 ENST00000429591.4
zinc finger protein 713
chr12_-_124567464 83.93 ENST00000458234.5
nuclear receptor corepressor 2
chr17_-_15999689 83.90 ENST00000399277.6
zinc finger SWIM-type containing 7
chr19_+_44905785 83.67 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr20_+_36154630 82.89 ENST00000338074.7
ENST00000636016.2
ENST00000373945.5
erythrocyte membrane protein band 4.1 like 1
chrX_-_13938618 82.45 ENST00000454189.6
glycoprotein M6B
chr9_-_96655280 82.38 ENST00000446045.1
ENST00000375234.8
peroxiredoxin like 2C
chr12_+_110281116 81.93 ENST00000308664.10
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
chr9_+_136665745 81.64 ENST00000371698.3
EGF like domain multiple 7
chr12_-_123972824 80.52 ENST00000238156.8
ENST00000545037.1
coiled-coil domain containing 92
chr12_-_54588636 80.32 ENST00000257905.13
protein phosphatase 1 regulatory inhibitor subunit 1A
chr3_-_132722365 80.26 ENST00000337331.10
ENST00000383282.3
ENST00000683570.1
nephrocystin 3
chr11_-_117876892 80.17 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr8_+_38901218 80.11 ENST00000521746.5
ENST00000616927.4
pleckstrin homology domain containing A2
chr16_+_85027735 79.63 ENST00000258180.7
ENST00000538274.5
KIAA0513
chr9_+_129665603 78.99 ENST00000372469.6
paired related homeobox 2
chr1_-_20486197 78.97 ENST00000375078.4
calcium/calmodulin dependent protein kinase II inhibitor 1
chr2_+_46297397 78.04 ENST00000263734.5
endothelial PAS domain protein 1
chr22_+_45502832 77.85 ENST00000455233.5
ENST00000402984.7
ENST00000262722.11
ENST00000327858.11
ENST00000442170.6
ENST00000340923.9
fibulin 1
chr14_+_96039328 77.81 ENST00000553764.1
ENST00000555004.3
ENST00000556728.1
ENST00000553782.1
chromosome 14 open reading frame 132
chr17_+_4807119 77.74 ENST00000263088.11
ENST00000572940.5
phospholipase D2
chr14_-_90816381 77.37 ENST00000328459.11
tetratricopeptide repeat domain 7B
chr15_+_68930488 76.96 ENST00000310673.4
ENST00000448182.7
ENST00000260364.9
sperm equatorial segment protein 1
NADPH oxidase 5
chr11_-_111912871 76.78 ENST00000528628.5
crystallin alpha B
chr7_-_158587710 76.54 ENST00000389416.8
protein tyrosine phosphatase receptor type N2
chr22_-_39152622 76.31 ENST00000216133.10
chromobox 7
chr15_+_68578970 76.13 ENST00000261861.10
coronin 2B
chr20_+_10218808 75.75 ENST00000254976.7
ENST00000304886.6
synaptosome associated protein 25
chr2_-_9003657 74.28 ENST00000462696.1
ENST00000305997.8
membrane bound O-acyltransferase domain containing 2
chr13_-_109786567 74.19 ENST00000375856.5
insulin receptor substrate 2
chr1_+_10210562 74.14 ENST00000377093.9
ENST00000676179.1
kinesin family member 1B
chr21_+_45643711 74.12 ENST00000681687.1
poly(rC) binding protein 3
chr1_-_2391535 73.85 ENST00000378531.8
MORN repeat containing 1
chr16_+_85027761 73.36 ENST00000683363.1
KIAA0513
chr20_-_36863517 73.28 ENST00000237536.9
suppressor of glucose, autophagy associated 1
chr6_-_29633171 72.99 ENST00000377034.9
gamma-aminobutyric acid type B receptor subunit 1
chr3_+_41199462 72.92 ENST00000647264.1
ENST00000645900.1
ENST00000646174.1
ENST00000643992.1
ENST00000647390.1
ENST00000642886.1
catenin beta 1
chr16_+_56632651 72.40 ENST00000379818.4
ENST00000570233.1
metallothionein 1M
chr7_-_139777774 72.34 ENST00000428878.6
homeodomain interacting protein kinase 2
chr4_-_8871817 72.29 ENST00000400677.5
H6 family homeobox 1
chr1_-_235649734 72.12 ENST00000391854.7
G protein subunit gamma 4
chr1_-_30908681 71.89 ENST00000339394.7
syndecan 3
chr9_+_17579059 71.61 ENST00000380607.5
SH3 domain containing GRB2 like 2, endophilin A1
chr19_-_18896081 71.52 ENST00000429504.6
ENST00000623882.4
ENST00000247005.8
ceramide synthase 1
growth differentiation factor 1
chr16_+_58500135 71.39 ENST00000563978.5
ENST00000569923.5
ENST00000356752.8
ENST00000563799.5
ENST00000562999.5
ENST00000570248.5
ENST00000562731.5
ENST00000568424.1
NDRG family member 4
chr11_-_111913134 70.94 ENST00000533971.2
ENST00000526180.6
crystallin alpha B
chr1_+_244835616 70.62 ENST00000366528.3
ENST00000411948.7
cytochrome c oxidase assembly factor COX20
chr9_+_137618986 70.58 ENST00000462484.5
ENST00000630754.2
ENST00000460843.6
ENST00000626216.2
ENST00000629335.2
euchromatic histone lysine methyltransferase 1
chr1_+_220690354 70.29 ENST00000294889.6
chromosome 1 open reading frame 115
chr20_-_49484258 70.21 ENST00000635465.1
potassium voltage-gated channel subfamily B member 1
chr5_+_77210667 70.21 ENST00000264917.10
phosphodiesterase 8B
chr8_-_19013693 69.94 ENST00000327040.13
pleckstrin and Sec7 domain containing 3
chr4_+_1793285 69.76 ENST00000440486.8
ENST00000412135.7
ENST00000481110.7
ENST00000340107.8
fibroblast growth factor receptor 3
chr11_-_2139382 69.62 ENST00000416167.7
insulin like growth factor 2
chr22_+_19714450 69.57 ENST00000455784.7
ENST00000406395.5
septin 5
chr20_+_59933761 69.13 ENST00000358293.7
family with sequence similarity 217 member B
chr6_-_29633056 68.75 ENST00000377016.8
gamma-aminobutyric acid type B receptor subunit 1
chr19_-_16472003 68.46 ENST00000248070.10
ENST00000594975.5
epidermal growth factor receptor pathway substrate 15 like 1
chr1_-_31764035 68.37 ENST00000373655.6
adhesion G protein-coupled receptor B2
chr7_-_103989516 68.10 ENST00000343529.9
ENST00000424685.3
reelin
chr7_+_45574358 67.74 ENST00000297323.12
adenylate cyclase 1
chr1_-_182391323 66.73 ENST00000642379.1
glutamate-ammonia ligase
chr20_-_63499074 66.58 ENST00000217182.6
ENST00000642899.1
eukaryotic translation elongation factor 1 alpha 2
chr4_-_5893075 66.42 ENST00000324989.12
collapsin response mediator protein 1
chr22_-_31346143 66.41 ENST00000405309.7
ENST00000351933.8
POZ/BTB and AT hook containing zinc finger 1
chr19_+_47256518 66.38 ENST00000643617.1
ENST00000221922.11
coiled-coil domain containing 9
chrX_+_7147819 66.28 ENST00000660000.2
steroid sulfatase
chr3_-_126475863 65.97 ENST00000336332.5
ENST00000389709.8
ZXD family zinc finger C
chr19_-_36032799 65.84 ENST00000592017.5
ENST00000360535.9
CAP-Gly domain containing linker protein 3
chr2_+_241356278 65.61 ENST00000264042.8
ENST00000627550.2
ENST00000373287.8
FERM, ARH/RhoGEF and pleckstrin domain protein 2
chr22_+_50600783 65.40 ENST00000329492.6
mitogen-activated protein kinase 8 interacting protein 2
chr2_+_20447065 65.32 ENST00000272233.6
ras homolog family member B
chr21_+_45643694 65.24 ENST00000400314.5
poly(rC) binding protein 3
chr18_-_5543988 65.10 ENST00000341928.7
erythrocyte membrane protein band 4.1 like 3
chr14_+_94174334 65.00 ENST00000328839.3
protein phosphatase 4 regulatory subunit 4
chr18_+_24014733 64.84 ENST00000317571.8
tetratricopeptide repeat domain 39C
chr12_-_123533705 64.83 ENST00000636882.1
ENST00000376874.9
Rab interacting lysosomal protein like 1
chr1_-_182391783 64.78 ENST00000331872.11
ENST00000339526.8
glutamate-ammonia ligase
chr1_-_31764333 64.76 ENST00000398542.5
ENST00000373658.8
adhesion G protein-coupled receptor B2
chr16_+_58500047 64.62 ENST00000566192.5
ENST00000565088.5
ENST00000568640.5
NDRG family member 4
chr12_+_53046969 64.61 ENST00000379902.7
tensin 2
chr10_-_79445617 64.42 ENST00000372336.4
zinc finger CCHC-type containing 24
chr16_-_352714 64.39 ENST00000262320.8
axin 1
chr16_+_69132590 64.26 ENST00000562237.5
ENST00000567460.5
ENST00000566227.5
ENST00000314423.12
ENST00000352319.8
ENST00000563094.5
UTP4 small subunit processome component
chr7_-_51316754 64.11 ENST00000632460.1
ENST00000441453.5
ENST00000648294.1
ENST00000265136.12
ENST00000395542.6
ENST00000395540.6
cordon-bleu WH2 repeat protein
chr13_-_30307539 63.92 ENST00000380615.8
katanin catalytic subunit A1 like 1
chr16_+_8674605 63.86 ENST00000268251.13
4-aminobutyrate aminotransferase
chr19_-_16471943 63.76 ENST00000602151.1
ENST00000597937.5
ENST00000455140.7
ENST00000535753.6
epidermal growth factor receptor pathway substrate 15 like 1
chr2_-_98936155 63.75 ENST00000428096.5
ENST00000397899.7
ENST00000420294.1
CRACD like
chr19_+_33194308 63.71 ENST00000253193.9
LDL receptor related protein 3
chr19_+_50203607 63.57 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr11_-_113875555 63.42 ENST00000003302.8
ENST00000545540.5
ubiquitin specific peptidase 28
chr7_-_44325617 63.40 ENST00000358707.7
ENST00000457475.5
calcium/calmodulin dependent protein kinase II beta
chr3_-_47578832 63.27 ENST00000264723.9
ENST00000610462.1
chondroitin sulfate proteoglycan 5
chr4_+_186144824 63.23 ENST00000227065.8
ENST00000502970.5
ENST00000514153.5
family with sequence similarity 149 member A
chr6_+_163414637 63.19 ENST00000453779.6
ENST00000275262.11
ENST00000392127.6
QKI, KH domain containing RNA binding
chr3_-_115147237 63.03 ENST00000357258.8
zinc finger and BTB domain containing 20
chr7_-_44325577 63.00 ENST00000395749.7
calcium/calmodulin dependent protein kinase II beta
chr11_-_117876719 62.71 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr7_-_4883683 62.41 ENST00000399583.4
Rap associating with DIL domain
chr8_+_140511286 62.34 ENST00000519533.1
ENST00000220913.10
chromatin accessibility complex subunit 1
chr14_-_21025000 62.17 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr1_+_3652508 62.16 ENST00000378295.9
ENST00000604074.5
tumor protein p73
chr11_+_125904467 62.10 ENST00000263576.11
ENST00000530414.5
ENST00000530129.6
DEAD-box helicase 25
chr16_+_87602478 61.84 ENST00000284262.3
junctophilin 3
chr20_+_24469623 61.64 ENST00000376862.4
synapse differentiation inducing 1
chr17_+_32486975 61.58 ENST00000313401.4
cyclin dependent kinase 5 regulatory subunit 1
chr22_+_49853801 61.50 ENST00000216268.6
zinc finger BED-type containing 4
chr20_+_1226035 61.49 ENST00000683101.1
ENST00000402452.5
ENST00000409241.5
ENST00000246108.3
RAD21 cohesin complex component like 1
chr9_+_136979042 61.45 ENST00000446677.2
prostaglandin D2 synthase
chr1_-_6180265 61.41 ENST00000262450.8
chromodomain helicase DNA binding protein 5
chr14_-_105300985 61.34 ENST00000619151.4
ENST00000547530.7
BRF1 RNA polymerase III transcription initiation factor subunit
chr9_-_13279407 61.25 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr22_-_43862480 61.22 ENST00000330884.9
sulfotransferase family 4A member 1
chr1_+_25616780 61.20 ENST00000374332.9
mannosidase alpha class 1C member 1
chr15_-_82647503 61.17 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr12_+_57216779 60.88 ENST00000349394.6
neurexophilin 4
chr15_+_72118392 60.87 ENST00000340912.6
SUMO peptidase family member, NEDD8 specific
chr19_-_49441508 60.85 ENST00000221485.8
solute carrier family 17 member 7
chr17_-_82698637 60.70 ENST00000538809.6
ENST00000269347.10
ENST00000571995.6
RAB40B, member RAS oncogene family
chr3_-_115147277 60.63 ENST00000675478.1
zinc finger and BTB domain containing 20
chr1_+_7784251 60.56 ENST00000377532.8
ENST00000377541.5
period circadian regulator 3
chr1_+_3652565 60.55 ENST00000354437.8
ENST00000357733.7
ENST00000346387.8
tumor protein p73
chr7_-_158587773 60.51 ENST00000389413.7
ENST00000409483.5
ENST00000389418.9
protein tyrosine phosphatase receptor type N2
chr1_-_157138474 60.48 ENST00000326786.4
ETS variant transcription factor 3
chr9_-_111038425 60.41 ENST00000441240.1
ENST00000683809.1
lysophosphatidic acid receptor 1
chr9_+_127611760 60.19 ENST00000625363.2
ENST00000626539.3
syntaxin binding protein 1
chr19_-_8832286 60.09 ENST00000601372.6
zinc finger protein 558
chr9_+_136980211 60.05 ENST00000444903.2
prostaglandin D2 synthase
chr6_-_83709141 59.82 ENST00000521743.5
synaptosome associated protein 91
chr10_+_119726041 59.67 ENST00000650623.2
ENST00000649251.1
inositol polyphosphate-5-phosphatase F
chr19_+_589873 59.44 ENST00000251287.3
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
chr16_+_56625775 59.28 ENST00000330439.7
ENST00000568293.1
metallothionein 1E
chr1_-_21622509 59.17 ENST00000374761.6
RAP1 GTPase activating protein
chr14_-_103521342 58.78 ENST00000553610.5
creatine kinase B
chr9_-_98708856 58.67 ENST00000259455.4
gamma-aminobutyric acid type B receptor subunit 2
chrX_+_136147465 58.63 ENST00000651929.2
four and a half LIM domains 1
chr20_-_3173516 58.51 ENST00000360342.7
ENST00000645462.1
ENST00000337576.7
leucine zipper tumor suppressor family member 3
chr1_-_52366124 58.39 ENST00000371586.6
ENST00000284376.8
coiled-coil and C2 domain containing 1B
chr7_-_103989649 58.35 ENST00000428762.6
reelin
chr17_-_42050587 58.33 ENST00000587304.3
chromosome 17 open reading frame 113
chr14_+_102777555 58.11 ENST00000539721.5
ENST00000560463.5
TNF receptor associated factor 3
chr10_+_46579084 58.10 ENST00000512997.5
ENST00000374321.9
ENST00000503753.5
synaptotagmin 15
chr22_+_50508216 57.71 ENST00000420993.7
ENST00000395698.7
ENST00000395701.7
ENST00000523045.5
ENST00000299821.15
non-SMC condensin II complex subunit H2
chr16_+_89828466 57.67 ENST00000378247.8
ENST00000393062.6
spire type actin nucleation factor 2
chr19_+_34481736 57.54 ENST00000590071.7
WT1 interacting protein
chr8_-_30812867 57.46 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr11_-_64643315 57.42 ENST00000301894.6
neurexin 2
chr9_-_137028271 57.29 ENST00000265662.9
ENST00000371605.7
ATP binding cassette subfamily A member 2
chr6_-_73452124 57.28 ENST00000680833.1
cyclic GMP-AMP synthase
chr4_+_7043315 57.25 ENST00000310074.8
ENST00000512388.1
transcriptional adaptor 2B
chr19_+_54415427 57.20 ENST00000301194.8
ENST00000376530.8
ENST00000445095.5
ENST00000376531.3
tweety family member 1
chr1_-_241357085 57.17 ENST00000366564.5
regulator of G protein signaling 7
chr19_+_1285859 56.92 ENST00000215368.4
ephrin A2
chr15_+_99251362 56.80 ENST00000558879.5
ENST00000301981.8
ENST00000447360.6
ENST00000558172.5
ENST00000561276.5
ENST00000331450.9
leucine rich repeat containing 28
chr1_-_223364059 56.71 ENST00000343846.7
ENST00000484758.6
ENST00000344029.6
ENST00000366878.9
ENST00000494793.6
ENST00000681285.1
ENST00000680429.1
ENST00000681669.1
ENST00000681305.1
sushi domain containing 4
chr8_+_141391989 56.68 ENST00000520105.5
ENST00000523147.5
ENST00000521578.6
protein tyrosine phosphatase 4A3
chr11_-_777467 56.65 ENST00000397472.6
ENST00000524550.5
ENST00000319863.13
ENST00000526325.5
glutamine amidotransferase like class 1 domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
61.1 305.7 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
49.0 293.8 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
47.1 141.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
47.0 140.9 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
43.6 174.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
43.2 129.6 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
40.6 40.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
37.4 112.1 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
36.8 110.5 GO:0036146 cellular response to mycotoxin(GO:0036146)
36.0 144.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
35.7 178.6 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
34.6 138.6 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
34.6 207.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
34.3 34.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
33.3 665.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
33.0 99.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
32.7 131.0 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
32.6 32.6 GO:0036090 cleavage furrow ingression(GO:0036090)
32.2 96.5 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
31.4 282.7 GO:0003190 atrioventricular valve formation(GO:0003190)
31.0 123.9 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
30.8 92.4 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
30.4 91.3 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
29.0 144.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
28.9 57.8 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
27.1 81.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
27.1 27.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
26.9 80.7 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
26.9 107.5 GO:1904980 positive regulation of endosome organization(GO:1904980)
26.2 78.6 GO:0098582 innate vocalization behavior(GO:0098582)
26.2 26.2 GO:0060353 regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
25.7 333.5 GO:2001135 regulation of endocytic recycling(GO:2001135)
25.7 102.6 GO:0033693 neurofilament bundle assembly(GO:0033693)
25.0 224.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
24.8 74.3 GO:0042137 sequestering of neurotransmitter(GO:0042137)
24.6 49.2 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
24.4 24.4 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
24.4 122.0 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
24.3 121.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
24.3 72.8 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
23.9 95.5 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
23.8 23.8 GO:0051957 positive regulation of amino acid transport(GO:0051957)
23.6 117.9 GO:0014807 regulation of somitogenesis(GO:0014807)
23.6 70.7 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
23.3 46.5 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
23.1 115.5 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
23.1 92.3 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
23.0 68.9 GO:0036049 protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
22.9 91.6 GO:0009305 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
22.4 67.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
22.1 110.6 GO:0006041 glucosamine metabolic process(GO:0006041)
22.1 66.3 GO:0060988 lipid tube assembly(GO:0060988)
22.0 66.0 GO:0001757 somite specification(GO:0001757)
21.6 64.7 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
21.0 63.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
21.0 21.0 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
21.0 41.9 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
20.7 124.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
20.6 61.9 GO:1990504 dense core granule exocytosis(GO:1990504)
20.5 123.0 GO:0038016 insulin receptor internalization(GO:0038016)
20.1 100.7 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
19.9 39.8 GO:0008354 germ cell migration(GO:0008354)
19.9 19.9 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
19.7 59.2 GO:0008355 olfactory learning(GO:0008355)
19.7 59.0 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
19.5 19.5 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
19.5 19.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
19.5 38.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208) dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
19.3 58.0 GO:0042412 taurine biosynthetic process(GO:0042412)
19.0 76.0 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
19.0 94.8 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
18.8 56.5 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
18.7 18.7 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
18.5 55.6 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
18.4 55.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
18.2 54.6 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
18.2 108.9 GO:1902722 positive regulation of prolactin secretion(GO:1902722)
17.9 89.5 GO:0008063 Toll signaling pathway(GO:0008063)
17.7 70.9 GO:0015670 carbon dioxide transport(GO:0015670)
17.7 17.7 GO:1903059 positive regulation of lipoprotein metabolic process(GO:0050747) regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
17.6 228.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
17.6 158.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
17.4 87.1 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
17.3 34.5 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
17.3 103.5 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
17.1 51.3 GO:0071494 cellular response to UV-C(GO:0071494)
17.0 101.7 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
16.9 101.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
16.8 151.5 GO:0060075 regulation of resting membrane potential(GO:0060075)
16.8 67.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
16.8 16.8 GO:1901529 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
16.7 33.4 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
16.7 66.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
16.6 49.9 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
16.6 83.2 GO:2001074 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
16.5 16.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
16.4 82.1 GO:0061107 seminal vesicle development(GO:0061107)
16.3 16.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
16.2 146.2 GO:0033578 protein glycosylation in Golgi(GO:0033578)
16.2 64.9 GO:0036369 transcription factor catabolic process(GO:0036369)
16.2 129.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
16.2 48.5 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
16.0 144.2 GO:0032482 Rab protein signal transduction(GO:0032482)
15.7 15.7 GO:0015870 acetylcholine transport(GO:0015870)
15.6 77.9 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
15.6 15.6 GO:0048549 positive regulation of pinocytosis(GO:0048549)
15.5 186.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
15.5 77.4 GO:0042415 norepinephrine metabolic process(GO:0042415)
15.5 77.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
15.4 153.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
15.3 92.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
15.3 30.6 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
15.2 91.3 GO:0071873 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
15.2 91.2 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
15.2 45.5 GO:0072237 metanephric proximal tubule development(GO:0072237)
15.1 120.8 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
15.0 30.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
14.9 59.7 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
14.9 44.6 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
14.9 29.7 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
14.8 133.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
14.7 102.6 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
14.6 14.6 GO:0023021 termination of signal transduction(GO:0023021)
14.6 14.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
14.5 14.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
14.4 14.4 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
14.4 71.8 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
14.4 114.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
14.3 14.3 GO:0070528 protein kinase C signaling(GO:0070528)
14.3 71.5 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
14.2 28.4 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
14.2 56.8 GO:0035627 ceramide transport(GO:0035627)
14.2 99.4 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
14.2 28.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
14.1 56.4 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
14.0 42.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
14.0 195.5 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
13.9 41.8 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
13.9 55.7 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
13.9 97.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
13.8 69.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
13.6 40.9 GO:1905073 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
13.6 54.3 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182)
13.5 54.2 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
13.5 13.5 GO:0060214 endocardium formation(GO:0060214)
13.5 40.5 GO:0003358 noradrenergic neuron development(GO:0003358)
13.3 13.3 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
13.3 79.8 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
13.3 53.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
13.2 79.3 GO:0060313 negative regulation of blood vessel remodeling(GO:0060313)
13.1 365.7 GO:0032011 ARF protein signal transduction(GO:0032011)
13.1 91.4 GO:0071321 cellular response to cGMP(GO:0071321)
13.0 91.0 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
13.0 13.0 GO:1903802 amino acid import into cell(GO:1902837) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
12.9 193.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
12.9 77.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
12.8 38.5 GO:1905232 cellular response to L-glutamate(GO:1905232)
12.8 63.9 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
12.7 38.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
12.7 63.6 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
12.7 114.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
12.6 87.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
12.5 37.6 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
12.4 24.8 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
12.3 592.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
12.3 245.9 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
12.3 36.8 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
12.2 48.8 GO:0051866 general adaptation syndrome(GO:0051866)
12.2 36.6 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
12.1 36.4 GO:0048865 stem cell fate commitment(GO:0048865)
12.0 48.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
12.0 71.9 GO:0016926 protein desumoylation(GO:0016926)
12.0 35.9 GO:0071812 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
11.9 119.5 GO:0014827 intestine smooth muscle contraction(GO:0014827)
11.9 83.5 GO:1902075 cellular response to salt(GO:1902075)
11.9 47.6 GO:1903610 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
11.9 130.8 GO:0016322 neuron remodeling(GO:0016322)
11.9 11.9 GO:1903960 negative regulation of anion transmembrane transport(GO:1903960)
11.8 94.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
11.8 11.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
11.7 116.6 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
11.6 23.3 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
11.6 150.8 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
11.6 34.8 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
11.6 81.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
11.6 23.2 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
11.6 23.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
11.5 114.5 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
11.4 57.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
11.4 125.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
11.3 34.0 GO:0071529 cementum mineralization(GO:0071529)
11.3 136.0 GO:0046958 nonassociative learning(GO:0046958)
11.3 22.7 GO:0008078 mesodermal cell migration(GO:0008078)
11.3 11.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
11.3 45.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
11.3 22.6 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
11.3 462.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
11.2 224.1 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
11.2 22.3 GO:0072300 positive regulation of metanephric glomerulus development(GO:0072300)
11.2 189.8 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
11.1 100.2 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
11.1 111.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
11.1 22.2 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
11.1 22.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
11.0 187.0 GO:0007021 tubulin complex assembly(GO:0007021)
11.0 21.9 GO:0030035 microspike assembly(GO:0030035)
11.0 32.9 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
10.9 130.8 GO:0042373 vitamin K metabolic process(GO:0042373)
10.8 32.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
10.8 10.8 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
10.8 21.6 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
10.8 54.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
10.7 64.5 GO:0035063 nuclear speck organization(GO:0035063)
10.7 32.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
10.7 10.7 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
10.7 21.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
10.6 63.9 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
10.6 31.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
10.6 52.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
10.6 179.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
10.5 10.5 GO:1900673 olefin metabolic process(GO:1900673)
10.5 31.6 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
10.5 31.6 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
10.5 73.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
10.5 42.0 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
10.5 42.0 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
10.5 20.9 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
10.5 31.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431)
10.4 31.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
10.4 31.2 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
10.4 20.7 GO:0030259 lipid glycosylation(GO:0030259)
10.3 51.5 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
10.3 41.2 GO:0048680 positive regulation of axon regeneration(GO:0048680)
10.3 20.6 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
10.2 61.4 GO:0036018 cellular response to erythropoietin(GO:0036018)
10.2 10.2 GO:0072014 proximal tubule development(GO:0072014)
10.2 71.4 GO:0051013 microtubule severing(GO:0051013)
10.2 40.7 GO:0002357 defense response to tumor cell(GO:0002357)
10.2 20.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
10.1 30.4 GO:0060022 hard palate development(GO:0060022)
10.1 50.7 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
10.1 111.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
10.1 60.6 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
10.0 29.9 GO:0002024 diet induced thermogenesis(GO:0002024)
10.0 49.8 GO:0046208 spermine catabolic process(GO:0046208)
9.9 99.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
9.9 19.9 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
9.9 19.8 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
9.9 128.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
9.9 29.6 GO:0070314 G1 to G0 transition(GO:0070314)
9.9 39.4 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
9.8 49.1 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
9.8 401.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
9.8 58.7 GO:0035617 stress granule disassembly(GO:0035617)
9.8 19.6 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
9.8 39.0 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
9.7 29.2 GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
9.7 19.4 GO:0035788 cell migration involved in kidney development(GO:0035787) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
9.7 19.4 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
9.7 58.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
9.6 28.9 GO:0060023 soft palate development(GO:0060023)
9.6 19.3 GO:0060437 lung growth(GO:0060437)
9.6 19.3 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
9.6 28.9 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
9.6 76.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
9.6 19.2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
9.6 28.7 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
9.6 28.7 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
9.6 258.2 GO:0048268 clathrin coat assembly(GO:0048268)
9.5 47.7 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
9.5 28.6 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
9.5 28.6 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
9.5 66.6 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
9.5 85.5 GO:0034465 response to carbon monoxide(GO:0034465)
9.5 28.5 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
9.5 18.9 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
9.5 66.2 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
9.5 28.4 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
9.4 85.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
9.4 56.7 GO:0055059 asymmetric neuroblast division(GO:0055059)
9.4 28.2 GO:0044565 dendritic cell proliferation(GO:0044565)
9.4 9.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
9.4 65.6 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
9.4 262.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
9.4 18.7 GO:0060032 notochord regression(GO:0060032)
9.4 9.4 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
9.3 18.7 GO:0061461 lysine transport(GO:0015819) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transport(GO:1902022) L-lysine import into cell(GO:1903410)
9.3 27.9 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
9.3 46.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
9.2 18.5 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
9.2 27.7 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
9.2 18.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
9.2 230.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
9.2 9.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
9.2 45.8 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
9.2 9.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
9.1 63.7 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
9.1 18.1 GO:0000436 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
9.1 27.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
9.0 198.8 GO:0097503 sialylation(GO:0097503)
9.0 36.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
9.0 72.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
9.0 72.1 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
9.0 98.8 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
9.0 26.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
8.9 35.8 GO:1990535 neuron projection maintenance(GO:1990535)
8.9 17.9 GO:2001202 negative regulation of transforming growth factor-beta secretion(GO:2001202)
8.9 499.5 GO:0015701 bicarbonate transport(GO:0015701)
8.9 169.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
8.9 17.8 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
8.9 26.7 GO:0061760 antifungal innate immune response(GO:0061760)
8.9 35.5 GO:0021759 globus pallidus development(GO:0021759)
8.8 44.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
8.8 26.5 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
8.8 35.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
8.8 26.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
8.8 61.3 GO:0035865 cellular response to potassium ion(GO:0035865)
8.7 17.5 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
8.7 69.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
8.7 209.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
8.7 113.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
8.7 69.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
8.6 8.6 GO:1990502 dense core granule maturation(GO:1990502)
8.6 8.6 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
8.5 501.3 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
8.5 254.9 GO:0071276 cellular response to cadmium ion(GO:0071276)
8.5 67.6 GO:0030322 stabilization of membrane potential(GO:0030322)
8.5 42.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
8.4 33.8 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
8.4 41.8 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
8.3 49.9 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
8.3 49.8 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
8.2 123.6 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
8.2 57.3 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
8.2 163.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
8.2 65.3 GO:1902669 positive regulation of axon guidance(GO:1902669)
8.2 32.6 GO:1904139 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
8.2 16.3 GO:0015808 L-alanine transport(GO:0015808)
8.1 32.6 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
8.1 8.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
8.1 138.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
8.1 8.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
8.1 8.1 GO:0001554 luteolysis(GO:0001554)
8.1 105.3 GO:0035095 behavioral response to nicotine(GO:0035095)
8.1 8.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
8.1 16.2 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
8.1 32.3 GO:0002159 desmosome assembly(GO:0002159)
8.0 87.9 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
8.0 31.8 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
7.9 15.9 GO:0035973 aggrephagy(GO:0035973)
7.9 63.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
7.9 55.5 GO:0018095 protein polyglutamylation(GO:0018095)
7.9 23.8 GO:0001842 neural fold formation(GO:0001842)
7.9 23.7 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
7.9 23.7 GO:0019075 virus maturation(GO:0019075)
7.9 15.7 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
7.9 23.6 GO:0045925 positive regulation of female receptivity(GO:0045925)
7.8 15.6 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
7.8 77.8 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
7.8 31.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
7.8 46.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
7.7 7.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
7.7 139.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
7.7 38.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
7.7 15.4 GO:0019086 late viral transcription(GO:0019086)
7.7 61.5 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
7.7 38.4 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
7.7 107.4 GO:0001946 lymphangiogenesis(GO:0001946)
7.7 23.0 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
7.7 15.3 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
7.6 45.7 GO:0071499 cellular response to laminar fluid shear stress(GO:0071499)
7.6 30.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
7.6 22.8 GO:0060736 prostate gland growth(GO:0060736)
7.6 15.2 GO:0001575 globoside metabolic process(GO:0001575)
7.6 37.8 GO:0060385 axonogenesis involved in innervation(GO:0060385)
7.5 52.8 GO:0046325 negative regulation of glucose import(GO:0046325)
7.5 45.3 GO:0007042 lysosomal lumen acidification(GO:0007042)
7.5 67.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
7.5 22.6 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
7.5 52.6 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
7.5 52.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
7.5 97.0 GO:0061141 lung ciliated cell differentiation(GO:0061141)
7.5 7.5 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
7.4 59.3 GO:0060137 maternal process involved in parturition(GO:0060137)
7.4 22.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
7.4 66.2 GO:0008090 retrograde axonal transport(GO:0008090)
7.3 66.1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
7.3 29.3 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
7.3 14.7 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
7.3 7.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
7.3 14.6 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
7.3 29.1 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
7.3 14.5 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
7.3 108.9 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
7.2 21.7 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
7.2 14.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
7.2 28.9 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
7.2 28.7 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
7.2 7.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
7.2 71.8 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
7.2 21.5 GO:0048243 norepinephrine secretion(GO:0048243)
7.2 21.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
7.1 35.6 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
7.1 42.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
7.1 14.2 GO:0051885 positive regulation of anagen(GO:0051885)
7.1 49.5 GO:0006068 ethanol catabolic process(GO:0006068)
7.1 28.3 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
7.1 7.1 GO:0045792 negative regulation of cell size(GO:0045792)
7.0 14.1 GO:0048840 otolith development(GO:0048840)
7.0 21.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
7.0 105.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
7.0 7.0 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
7.0 14.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
7.0 70.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
7.0 21.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
7.0 21.0 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
7.0 258.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
7.0 41.8 GO:0071105 response to interleukin-11(GO:0071105)
6.9 13.9 GO:0072254 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
6.9 55.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
6.9 41.6 GO:0060453 regulation of gastric acid secretion(GO:0060453)
6.9 27.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
6.9 13.9 GO:0072344 rescue of stalled ribosome(GO:0072344)
6.9 27.7 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
6.9 27.7 GO:0038161 prolactin signaling pathway(GO:0038161)
6.9 20.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
6.9 55.2 GO:0035524 proline transmembrane transport(GO:0035524)
6.9 20.7 GO:0045759 negative regulation of action potential(GO:0045759)
6.9 41.4 GO:0031642 negative regulation of myelination(GO:0031642)
6.9 13.8 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
6.9 289.4 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
6.9 82.7 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
6.9 41.3 GO:0097090 presynaptic membrane organization(GO:0097090)
6.9 75.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
6.9 20.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
6.8 6.8 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
6.8 67.8 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
6.8 13.5 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
6.8 60.9 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
6.8 27.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
6.7 141.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
6.7 20.2 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
6.7 20.1 GO:1902617 response to fluoride(GO:1902617)
6.7 6.7 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
6.7 26.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
6.7 20.0 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
6.7 39.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
6.6 26.6 GO:0046351 disaccharide biosynthetic process(GO:0046351)
6.6 72.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
6.6 33.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
6.6 19.8 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
6.6 26.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
6.6 85.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
6.5 58.8 GO:0098535 de novo centriole assembly(GO:0098535)
6.5 19.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
6.5 6.5 GO:0009996 negative regulation of cell fate specification(GO:0009996)
6.5 6.5 GO:0071284 cellular response to lead ion(GO:0071284)
6.5 142.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
6.5 174.7 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
6.4 45.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
6.4 206.1 GO:0008045 motor neuron axon guidance(GO:0008045)
6.4 19.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
6.4 121.7 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
6.4 12.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
6.4 102.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
6.4 152.9 GO:0048854 brain morphogenesis(GO:0048854)
6.4 69.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
6.3 12.7 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
6.3 44.3 GO:0031643 positive regulation of myelination(GO:0031643)
6.3 25.3 GO:0042360 vitamin E metabolic process(GO:0042360)
6.3 6.3 GO:0002265 astrocyte activation involved in immune response(GO:0002265)
6.3 12.6 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
6.3 31.5 GO:0060346 bone trabecula formation(GO:0060346)
6.3 6.3 GO:1990834 response to odorant(GO:1990834)
6.3 18.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
6.3 31.3 GO:0071625 vocalization behavior(GO:0071625)
6.2 56.2 GO:0060068 vagina development(GO:0060068)
6.2 62.3 GO:0007413 axonal fasciculation(GO:0007413)
6.2 31.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
6.2 86.8 GO:0008089 anterograde axonal transport(GO:0008089)
6.2 61.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
6.1 30.7 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
6.1 24.5 GO:0032286 central nervous system myelin maintenance(GO:0032286)
6.1 42.9 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
6.1 6.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
6.1 18.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
6.1 12.2 GO:0072189 ureter development(GO:0072189)
6.1 24.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
6.1 48.6 GO:0061709 reticulophagy(GO:0061709)
6.1 54.5 GO:0008343 adult feeding behavior(GO:0008343)
6.0 24.2 GO:0021781 glial cell fate commitment(GO:0021781)
6.0 18.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
6.0 6.0 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
6.0 11.9 GO:0021979 hypothalamus cell differentiation(GO:0021979)
6.0 23.9 GO:0033504 floor plate development(GO:0033504)
6.0 11.9 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
6.0 29.8 GO:0010829 negative regulation of glucose transport(GO:0010829)
6.0 23.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
5.9 35.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
5.9 23.7 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
5.9 11.8 GO:2001225 regulation of chloride transport(GO:2001225)
5.9 11.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
5.9 53.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
5.9 29.5 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
5.9 64.7 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
5.9 17.6 GO:0043615 astrocyte cell migration(GO:0043615)
5.9 29.4 GO:0030070 insulin processing(GO:0030070)
5.8 23.4 GO:1902473 regulation of protein localization to synapse(GO:1902473)
5.8 58.2 GO:0015871 choline transport(GO:0015871)
5.8 75.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
5.8 11.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
5.8 17.4 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
5.8 17.3 GO:0061209 cell proliferation involved in mesonephros development(GO:0061209)
5.8 5.8 GO:0061743 motor learning(GO:0061743)
5.8 17.3 GO:0009386 translational attenuation(GO:0009386)
5.8 63.4 GO:0097091 synaptic vesicle clustering(GO:0097091)
5.8 5.8 GO:0021794 thalamus development(GO:0021794)
5.8 97.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
5.7 51.7 GO:0051446 positive regulation of meiotic cell cycle(GO:0051446)
5.7 17.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
5.7 40.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
5.7 17.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030)
5.7 80.1 GO:0006776 vitamin A metabolic process(GO:0006776)
5.7 17.2 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
5.7 17.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
5.7 5.7 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
5.7 28.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
5.7 17.1 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
5.7 22.8 GO:0048630 skeletal muscle tissue growth(GO:0048630)
5.7 5.7 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
5.7 17.1 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
5.7 45.3 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
5.7 28.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
5.7 34.0 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
5.7 84.8 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
5.6 16.9 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
5.6 140.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
5.6 22.5 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
5.6 44.8 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
5.6 16.8 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
5.6 16.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
5.6 16.8 GO:0006566 threonine metabolic process(GO:0006566)
5.6 27.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072) glycerol-3-phosphate biosynthetic process(GO:0046167)
5.6 156.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
5.6 44.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
5.6 22.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
5.5 72.1 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
5.5 105.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
5.5 148.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
5.5 27.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
5.5 16.5 GO:0042756 drinking behavior(GO:0042756)
5.5 54.9 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
5.5 98.6 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
5.5 16.4 GO:0048570 notochord morphogenesis(GO:0048570)
5.5 10.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
5.4 32.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
5.4 174.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
5.4 5.4 GO:0070471 uterine smooth muscle contraction(GO:0070471)
5.4 37.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
5.4 64.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
5.4 5.4 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
5.4 21.6 GO:0007622 rhythmic behavior(GO:0007622)
5.4 226.5 GO:0019228 neuronal action potential(GO:0019228)
5.4 5.4 GO:0071500 cellular response to nitrosative stress(GO:0071500)
5.4 10.8 GO:0060938 cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
5.4 10.7 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
5.4 128.9 GO:0006706 steroid catabolic process(GO:0006706)
5.4 37.5 GO:0006983 ER overload response(GO:0006983)
5.3 26.7 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
5.3 26.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
5.3 21.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
5.3 31.7 GO:0036342 post-anal tail morphogenesis(GO:0036342)
5.3 10.6 GO:1902414 protein localization to cell junction(GO:1902414)
5.3 15.9 GO:0046521 sphingoid catabolic process(GO:0046521)
5.3 63.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
5.3 5.3 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
5.2 26.2 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
5.2 20.9 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
5.2 15.7 GO:1990108 protein linear deubiquitination(GO:1990108)
5.2 15.6 GO:0036292 DNA rewinding(GO:0036292)
5.2 46.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
5.2 5.2 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
5.2 26.0 GO:0072178 nephric duct morphogenesis(GO:0072178)
5.2 20.8 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
5.2 5.2 GO:0005985 sucrose metabolic process(GO:0005985)
5.2 15.6 GO:0007518 myoblast fate determination(GO:0007518)
5.2 20.7 GO:1902018 negative regulation of cilium assembly(GO:1902018)
5.2 41.3 GO:1903859 regulation of dendrite extension(GO:1903859)
5.2 20.7 GO:0071418 cellular response to amine stimulus(GO:0071418)
5.1 92.7 GO:0018345 protein palmitoylation(GO:0018345)
5.1 20.6 GO:0034334 adherens junction maintenance(GO:0034334)
5.1 10.3 GO:0042940 D-amino acid transport(GO:0042940)
5.1 82.1 GO:2000505 regulation of energy homeostasis(GO:2000505)
5.1 15.3 GO:0009404 toxin metabolic process(GO:0009404)
5.1 56.2 GO:0032060 bleb assembly(GO:0032060)
5.1 30.6 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
5.1 56.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
5.1 45.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
5.1 285.0 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
5.1 15.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
5.1 10.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
5.1 136.9 GO:0046329 negative regulation of JNK cascade(GO:0046329)
5.1 10.1 GO:0035634 response to stilbenoid(GO:0035634)
5.1 45.5 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
5.1 86.0 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
5.0 15.1 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
5.0 5.0 GO:0015740 C4-dicarboxylate transport(GO:0015740)
5.0 20.2 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
5.0 5.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
5.0 15.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
5.0 15.0 GO:0018094 protein polyglycylation(GO:0018094)
5.0 10.0 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
5.0 135.2 GO:0035640 exploration behavior(GO:0035640)
5.0 30.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
5.0 35.0 GO:0043589 skin morphogenesis(GO:0043589)
5.0 5.0 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
4.9 24.7 GO:0042574 retinal metabolic process(GO:0042574)
4.9 34.6 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
4.9 19.7 GO:0031627 telomeric loop formation(GO:0031627)
4.9 4.9 GO:0007521 muscle cell fate determination(GO:0007521)
4.9 4.9 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
4.9 34.0 GO:0072757 cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563)
4.8 14.5 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
4.8 9.7 GO:1990637 response to prolactin(GO:1990637)
4.8 19.4 GO:1990928 response to amino acid starvation(GO:1990928)
4.8 19.2 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889)
4.8 38.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
4.8 4.8 GO:1903056 regulation of melanosome organization(GO:1903056)
4.8 43.0 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
4.8 14.3 GO:0032455 nerve growth factor processing(GO:0032455)
4.8 9.5 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
4.8 19.0 GO:0038092 nodal signaling pathway(GO:0038092)
4.8 80.8 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
4.7 33.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
4.7 23.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
4.7 4.7 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
4.7 14.1 GO:0061163 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
4.7 28.2 GO:0071896 protein localization to adherens junction(GO:0071896)
4.7 28.1 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
4.7 28.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
4.7 9.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
4.7 18.7 GO:0035610 protein side chain deglutamylation(GO:0035610)
4.7 4.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
4.7 23.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
4.6 69.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
4.6 116.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
4.6 9.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
4.6 78.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
4.6 23.2 GO:0006684 sphingomyelin metabolic process(GO:0006684)
4.6 27.8 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
4.6 50.9 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
4.6 9.2 GO:0005513 detection of calcium ion(GO:0005513)
4.6 13.8 GO:0072033 renal vesicle formation(GO:0072033) ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
4.6 18.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
4.6 50.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
4.6 4.6 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
4.6 4.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
4.6 9.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
4.6 13.7 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
4.5 9.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
4.5 58.8 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
4.5 13.6 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
4.5 13.6 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
4.5 13.5 GO:0035330 regulation of hippo signaling(GO:0035330)
4.5 130.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
4.5 17.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
4.5 8.9 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
4.5 13.4 GO:1903537 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
4.5 4.5 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
4.4 4.4 GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
4.4 8.9 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
4.4 269.6 GO:1902476 chloride transmembrane transport(GO:1902476)
4.4 22.0 GO:0045161 neuronal ion channel clustering(GO:0045161)
4.4 70.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
4.4 8.8 GO:0021997 neural plate axis specification(GO:0021997)
4.4 48.1 GO:0035878 nail development(GO:0035878)
4.4 26.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
4.3 26.0 GO:1902731 negative regulation of chondrocyte proliferation(GO:1902731)
4.3 34.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
4.3 4.3 GO:1903527 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
4.3 38.9 GO:0033127 regulation of histone phosphorylation(GO:0033127)
4.3 4.3 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
4.3 21.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
4.3 8.6 GO:0032466 negative regulation of cytokinesis(GO:0032466)
4.3 167.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
4.3 77.2 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
4.3 21.4 GO:0042118 endothelial cell activation(GO:0042118)
4.3 4.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
4.3 17.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
4.3 17.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
4.3 17.0 GO:0050771 negative regulation of axonogenesis(GO:0050771)
4.3 59.5 GO:0045921 positive regulation of exocytosis(GO:0045921)
4.2 229.1 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773)
4.2 8.5 GO:2001186 regulation of T cell antigen processing and presentation(GO:0002625) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
4.2 33.8 GO:1900274 regulation of phospholipase C activity(GO:1900274)
4.2 16.9 GO:0046952 ketone body catabolic process(GO:0046952)
4.2 29.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
4.2 12.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
4.2 50.3 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
4.2 29.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
4.2 4.2 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
4.2 41.6 GO:0015919 peroxisomal membrane transport(GO:0015919)
4.2 20.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
4.2 8.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate proteoglycan metabolic process(GO:0050655)
4.1 70.2 GO:0003322 pancreatic A cell development(GO:0003322)
4.1 12.4 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
4.1 227.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
4.1 12.4 GO:0009720 detection of hormone stimulus(GO:0009720)
4.1 4.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
4.1 12.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
4.1 24.7 GO:0097186 amelogenesis(GO:0097186)
4.1 16.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
4.1 16.3 GO:0072311 glomerular epithelial cell differentiation(GO:0072311)
4.1 8.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
4.1 40.5 GO:0042417 dopamine metabolic process(GO:0042417)
4.1 12.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
4.1 8.1 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
4.0 8.0 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
4.0 4.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
4.0 12.1 GO:0030517 negative regulation of axon extension(GO:0030517)
4.0 12.0 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
4.0 12.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
4.0 51.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
4.0 19.9 GO:0044065 regulation of respiratory system process(GO:0044065)
4.0 35.9 GO:0060856 establishment of blood-brain barrier(GO:0060856)
4.0 19.9 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
4.0 4.0 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
4.0 15.9 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
4.0 59.6 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
4.0 15.9 GO:0010762 regulation of fibroblast migration(GO:0010762)
4.0 11.9 GO:1902490 regulation of sperm capacitation(GO:1902490)
3.9 3.9 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
3.9 3.9 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
3.9 35.3 GO:0038065 collagen-activated signaling pathway(GO:0038065)
3.9 3.9 GO:0010543 regulation of platelet activation(GO:0010543)
3.9 3.9 GO:0002118 aggressive behavior(GO:0002118)
3.9 11.6 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
3.9 42.7 GO:2000291 regulation of myoblast proliferation(GO:2000291)
3.9 54.2 GO:0008038 neuron recognition(GO:0008038)
3.9 15.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
3.9 11.6 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
3.9 27.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
3.9 30.9 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
3.9 7.7 GO:0003343 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
3.9 38.5 GO:0007258 JUN phosphorylation(GO:0007258)
3.9 11.6 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430)
3.8 34.6 GO:0072592 oxygen metabolic process(GO:0072592)
3.8 42.2 GO:0021681 cerebellar granular layer development(GO:0021681)
3.8 7.7 GO:0070634 transepithelial ammonium transport(GO:0070634)
3.8 7.7 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
3.8 7.7 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
3.8 19.1 GO:0060294 cilium movement involved in cell motility(GO:0060294)
3.8 80.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
3.8 7.6 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
3.8 22.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
3.8 7.6 GO:0007538 primary sex determination(GO:0007538)
3.8 3.8 GO:0009397 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
3.8 18.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
3.8 11.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
3.8 30.0 GO:0007252 I-kappaB phosphorylation(GO:0007252)
3.7 22.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
3.7 11.2 GO:0048102 autophagic cell death(GO:0048102)
3.7 7.4 GO:0046173 polyol biosynthetic process(GO:0046173)
3.7 7.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
3.7 22.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
3.7 7.4 GO:0051684 maintenance of Golgi location(GO:0051684)
3.7 26.0 GO:0097152 mesenchymal cell apoptotic process(GO:0097152)
3.7 11.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
3.7 3.7 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
3.7 14.8 GO:0097484 dendrite extension(GO:0097484)
3.7 199.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
3.7 3.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
3.6 10.9 GO:0044804 nucleophagy(GO:0044804)
3.6 18.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
3.6 10.9 GO:0070625 zymogen granule exocytosis(GO:0070625)
3.6 18.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
3.6 3.6 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
3.6 83.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
3.6 32.6 GO:0015886 heme transport(GO:0015886)
3.6 3.6 GO:0060290 transdifferentiation(GO:0060290)
3.6 7.2 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
3.6 3.6 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
3.6 25.1 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
3.6 10.8 GO:0071850 mitotic cell cycle arrest(GO:0071850)
3.6 32.2 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
3.6 7.1 GO:0009750 response to fructose(GO:0009750)
3.6 3.6 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
3.6 21.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
3.6 10.7 GO:0010847 regulation of chromatin assembly(GO:0010847)
3.6 3.6 GO:0097084 vascular smooth muscle cell development(GO:0097084)
3.6 17.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
3.5 14.2 GO:0045176 apical protein localization(GO:0045176)
3.5 31.9 GO:0021854 hypothalamus development(GO:0021854)
3.5 10.6 GO:0072017 distal tubule development(GO:0072017)
3.5 21.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
3.5 45.9 GO:0035493 SNARE complex assembly(GO:0035493)
3.5 10.6 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
3.5 7.0 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
3.5 10.5 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
3.5 38.3 GO:0048251 elastic fiber assembly(GO:0048251)
3.5 10.4 GO:0010934 macrophage cytokine production(GO:0010934)
3.5 24.3 GO:0043249 erythrocyte maturation(GO:0043249)
3.5 145.2 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
3.4 6.9 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
3.4 3.4 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) embryonic heart tube left/right pattern formation(GO:0060971)
3.4 3.4 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
3.4 65.1 GO:0006895 Golgi to endosome transport(GO:0006895)
3.4 20.5 GO:0034201 response to oleic acid(GO:0034201)
3.4 17.1 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
3.4 27.3 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
3.4 44.2 GO:0097062 dendritic spine maintenance(GO:0097062)
3.4 20.4 GO:0043116 negative regulation of vascular permeability(GO:0043116)
3.4 13.6 GO:0071233 cellular response to leucine(GO:0071233)
3.4 81.4 GO:0014850 response to muscle activity(GO:0014850)
3.4 20.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
3.4 6.7 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
3.4 3.4 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
3.3 26.8 GO:0030539 male genitalia development(GO:0030539)
3.3 53.5 GO:0006853 carnitine shuttle(GO:0006853)
3.3 13.4 GO:0072719 cellular response to cisplatin(GO:0072719)
3.3 6.7 GO:0007288 sperm axoneme assembly(GO:0007288)
3.3 3.3 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
3.3 16.6 GO:0007512 adult heart development(GO:0007512)
3.3 460.2 GO:0006813 potassium ion transport(GO:0006813)
3.3 9.9 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
3.3 6.6 GO:0002371 dendritic cell cytokine production(GO:0002371)
3.3 26.4 GO:0070633 transepithelial transport(GO:0070633)
3.3 42.9 GO:0006600 creatine metabolic process(GO:0006600)
3.3 19.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
3.3 52.2 GO:0097576 vacuole fusion(GO:0097576)
3.3 16.3 GO:0060591 chondroblast differentiation(GO:0060591)
3.3 42.3 GO:0036124 histone H3-K9 trimethylation(GO:0036124)
3.3 22.8 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
3.3 52.0 GO:0009068 aspartate family amino acid catabolic process(GO:0009068)
3.2 25.9 GO:0007506 gonadal mesoderm development(GO:0007506)
3.2 3.2 GO:0001696 gastric acid secretion(GO:0001696)
3.2 12.9 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
3.2 128.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
3.2 3.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
3.2 9.6 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
3.2 9.6 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
3.2 31.8 GO:0021988 olfactory lobe development(GO:0021988)
3.1 3.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
3.1 12.5 GO:0015705 iodide transport(GO:0015705)
3.1 49.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
3.1 71.4 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
3.1 21.6 GO:0015874 norepinephrine transport(GO:0015874)
3.1 3.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
3.1 6.1 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
3.1 18.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
3.0 12.2 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
3.0 3.0 GO:0042938 dipeptide transport(GO:0042938)
3.0 3.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
3.0 30.2 GO:0021954 central nervous system neuron development(GO:0021954)
3.0 15.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681) regulation of endothelial tube morphogenesis(GO:1901509)
3.0 12.0 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
3.0 12.0 GO:0090009 primitive streak formation(GO:0090009)
3.0 3.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
3.0 11.9 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
3.0 20.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
3.0 38.6 GO:0007398 ectoderm development(GO:0007398)
3.0 213.1 GO:0007626 locomotory behavior(GO:0007626)
2.9 44.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
2.9 5.9 GO:0034091 regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
2.9 5.9 GO:2000520 positive regulation of mononuclear cell migration(GO:0071677) regulation of immunological synapse formation(GO:2000520) negative regulation of immunological synapse formation(GO:2000521) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
2.9 2.9 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
2.9 14.6 GO:0071711 basement membrane organization(GO:0071711)
2.9 8.8 GO:0015847 putrescine transport(GO:0015847)
2.9 20.5 GO:0007616 long-term memory(GO:0007616)
2.9 20.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
2.9 8.8 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.9 204.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
2.9 5.8 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
2.9 115.3 GO:0001578 microtubule bundle formation(GO:0001578)
2.9 2.9 GO:0046110 xanthine metabolic process(GO:0046110)
2.9 14.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
2.8 8.5 GO:0034371 chylomicron remodeling(GO:0034371)
2.8 5.7 GO:0043504 mitochondrial DNA repair(GO:0043504)
2.8 195.2 GO:0030574 collagen catabolic process(GO:0030574)
2.8 56.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
2.8 16.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
2.8 84.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
2.8 5.6 GO:0021523 somatic motor neuron differentiation(GO:0021523)
2.8 5.6 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
2.8 13.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
2.8 8.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
2.8 13.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
2.8 13.8 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
2.8 47.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
2.8 8.3 GO:0045821 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821)
2.8 19.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
2.7 11.0 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
2.7 35.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
2.7 10.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
2.7 10.8 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
2.7 27.0 GO:0070544 histone H3-K36 demethylation(GO:0070544)
2.7 8.1 GO:0070105 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.7 16.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
2.7 16.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
2.7 10.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
2.7 2.7 GO:0030916 otic vesicle formation(GO:0030916)
2.7 5.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
2.7 5.3 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
2.6 18.5 GO:0006537 glutamate biosynthetic process(GO:0006537)
2.6 13.2 GO:0021544 subpallium development(GO:0021544)
2.6 18.5 GO:0032594 protein transport within lipid bilayer(GO:0032594)
2.6 7.9 GO:0019344 cysteine biosynthetic process(GO:0019344)
2.6 2.6 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
2.6 7.9 GO:0019046 release from viral latency(GO:0019046)
2.6 13.1 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
2.6 10.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
2.6 7.8 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
2.6 5.2 GO:1901626 regulation of postsynaptic membrane organization(GO:1901626)
2.6 10.3 GO:0045023 G0 to G1 transition(GO:0045023)
2.6 10.3 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
2.6 10.3 GO:0047484 regulation of response to osmotic stress(GO:0047484)
2.6 10.3 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
2.6 12.8 GO:0001573 ganglioside metabolic process(GO:0001573)
2.6 20.4 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
2.6 2.6 GO:0048841 regulation of axon extension involved in axon guidance(GO:0048841)
2.5 10.2 GO:0018343 protein farnesylation(GO:0018343)
2.5 127.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
2.5 10.1 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
2.5 22.7 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
2.5 7.5 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
2.5 12.6 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
2.5 5.0 GO:0001826 inner cell mass cell differentiation(GO:0001826)
2.5 60.3 GO:0007416 synapse assembly(GO:0007416)
2.5 2.5 GO:1901420 negative regulation of response to alcohol(GO:1901420)
2.5 40.1 GO:0050901 leukocyte tethering or rolling(GO:0050901)
2.5 2.5 GO:0050915 sensory perception of sour taste(GO:0050915)
2.5 5.0 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
2.5 106.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
2.5 17.3 GO:0032025 response to cobalt ion(GO:0032025)
2.5 103.6 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
2.5 7.4 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
2.4 26.8 GO:0070734 histone H3-K27 methylation(GO:0070734)
2.4 9.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
2.4 4.8 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
2.4 4.8 GO:0015872 dopamine transport(GO:0015872)
2.4 4.8 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
2.4 12.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
2.4 26.2 GO:0001778 plasma membrane repair(GO:0001778)
2.4 7.1 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
2.4 7.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
2.4 4.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
2.4 4.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
2.3 7.0 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
2.3 4.7 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
2.3 28.0 GO:0060008 Sertoli cell differentiation(GO:0060008)
2.3 13.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
2.3 27.8 GO:0006590 thyroid hormone generation(GO:0006590)
2.3 20.8 GO:0003351 epithelial cilium movement(GO:0003351)
2.3 9.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
2.3 9.3 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
2.3 16.1 GO:0042148 strand invasion(GO:0042148)
2.3 2.3 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
2.3 6.9 GO:0044848 biological phase(GO:0044848)
2.3 11.5 GO:0000733 DNA strand renaturation(GO:0000733)
2.3 16.0 GO:0021516 dorsal spinal cord development(GO:0021516)
2.3 54.5 GO:0030488 tRNA methylation(GO:0030488)
2.3 2.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
2.3 15.8 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
2.2 2.2 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
2.2 2.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
2.2 2.2 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
2.2 6.7 GO:0038001 paracrine signaling(GO:0038001)
2.2 11.2 GO:0048485 sympathetic nervous system development(GO:0048485)
2.2 4.5 GO:0048664 neuron fate determination(GO:0048664)
2.2 13.3 GO:0007256 activation of JNKK activity(GO:0007256)
2.2 11.1 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
2.2 8.8 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
2.2 8.8 GO:0034628 aspartate metabolic process(GO:0006531) nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
2.2 232.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
2.2 4.4 GO:0014002 astrocyte development(GO:0014002)
2.2 58.9 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
2.2 10.9 GO:0034453 microtubule anchoring(GO:0034453)
2.2 13.0 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
2.2 4.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
2.2 30.2 GO:0016576 histone dephosphorylation(GO:0016576)
2.1 4.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
2.1 55.7 GO:0006836 neurotransmitter transport(GO:0006836)
2.1 10.7 GO:0019323 pentose catabolic process(GO:0019323)
2.1 8.5 GO:0021542 dentate gyrus development(GO:0021542)
2.1 2.1 GO:0021571 rhombomere 5 development(GO:0021571)
2.1 2.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
2.1 4.2 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
2.1 18.9 GO:0002026 regulation of the force of heart contraction(GO:0002026)
2.1 6.3 GO:0036245 cellular response to menadione(GO:0036245)
2.1 20.6 GO:0071285 cellular response to lithium ion(GO:0071285)
2.1 26.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
2.0 81.9 GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187)
2.0 10.2 GO:0032456 endocytic recycling(GO:0032456)
2.0 18.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
2.0 4.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
2.0 2.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
2.0 6.0 GO:0021670 lateral ventricle development(GO:0021670)
2.0 8.0 GO:0042182 ketone catabolic process(GO:0042182)
2.0 4.0 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
2.0 4.0 GO:0021871 forebrain regionalization(GO:0021871)
2.0 13.8 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
2.0 5.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
2.0 3.9 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
2.0 3.9 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
1.9 59.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
1.9 1.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
1.9 1.9 GO:0003264 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
1.9 15.0 GO:0001755 neural crest cell migration(GO:0001755)
1.9 13.0 GO:0047496 vesicle transport along microtubule(GO:0047496)
1.9 13.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.9 7.4 GO:0001555 oocyte growth(GO:0001555)
1.8 3.7 GO:1902358 sulfate transmembrane transport(GO:1902358)
1.8 21.9 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
1.8 1.8 GO:2000382 positive regulation of mesoderm development(GO:2000382)
1.8 27.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
1.8 3.6 GO:0060384 innervation(GO:0060384)
1.8 9.0 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
1.8 5.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.8 8.9 GO:0031018 endocrine pancreas development(GO:0031018)
1.8 1.8 GO:0001955 blood vessel maturation(GO:0001955)
1.8 1.8 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
1.7 8.7 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
1.7 1.7 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662)
1.7 15.7 GO:0042359 vitamin D metabolic process(GO:0042359)
1.7 1.7 GO:0033227 dsRNA transport(GO:0033227)
1.7 3.5 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
1.7 10.4 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
1.7 8.6 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
1.7 17.2 GO:0003416 endochondral bone growth(GO:0003416)
1.7 29.2 GO:0046323 glucose import(GO:0046323)
1.7 8.5 GO:0043691 reverse cholesterol transport(GO:0043691)
1.7 11.9 GO:0001947 heart looping(GO:0001947)
1.7 1.7 GO:0055075 potassium ion homeostasis(GO:0055075)
1.7 5.1 GO:1990403 embryonic brain development(GO:1990403)
1.7 1.7 GO:0032275 luteinizing hormone secretion(GO:0032275)
1.7 6.8 GO:0001508 action potential(GO:0001508)
1.7 15.2 GO:0044030 regulation of DNA methylation(GO:0044030)
1.7 1.7 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
1.7 11.8 GO:0090042 tubulin deacetylation(GO:0090042)
1.7 42.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
1.7 13.4 GO:0010996 response to auditory stimulus(GO:0010996)
1.7 23.3 GO:0042572 retinol metabolic process(GO:0042572)
1.7 3.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
1.6 9.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
1.6 4.8 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
1.6 9.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.6 4.7 GO:0030578 PML body organization(GO:0030578)
1.6 7.9 GO:0035635 entry of bacterium into host cell(GO:0035635)
1.6 17.2 GO:0036065 fucosylation(GO:0036065)
1.6 4.7 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
1.5 10.7 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
1.5 4.6 GO:0046519 sphingoid metabolic process(GO:0046519)
1.5 4.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
1.5 4.5 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
1.5 4.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.5 3.0 GO:0061386 closure of optic fissure(GO:0061386)
1.5 17.6 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
1.5 32.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
1.5 4.4 GO:0051414 response to cortisol(GO:0051414)
1.5 4.4 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
1.5 8.7 GO:0002784 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
1.5 7.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
1.4 8.6 GO:0097120 receptor localization to synapse(GO:0097120)
1.4 4.3 GO:0006681 galactosylceramide metabolic process(GO:0006681) galactosylceramide catabolic process(GO:0006683)
1.4 7.1 GO:0045007 depurination(GO:0045007)
1.4 5.6 GO:0060700 regulation of ribonuclease activity(GO:0060700)
1.4 11.3 GO:0061037 negative regulation of cartilage development(GO:0061037)
1.4 5.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.4 1.4 GO:0051133 regulation of NK T cell activation(GO:0051133)
1.4 16.4 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
1.4 5.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
1.4 2.7 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593) negative regulation of lamellipodium organization(GO:1902744)
1.4 54.3 GO:0007041 lysosomal transport(GO:0007041)
1.4 9.5 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
1.4 28.4 GO:0007368 determination of left/right symmetry(GO:0007368)
1.3 5.4 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
1.3 2.7 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
1.3 6.6 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
1.3 5.3 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
1.3 9.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
1.3 7.9 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
1.3 2.6 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
1.3 92.4 GO:0090630 activation of GTPase activity(GO:0090630)
1.3 28.5 GO:0001706 endoderm formation(GO:0001706)
1.3 7.8 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
1.3 1.3 GO:0006113 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
1.3 3.9 GO:0071421 manganese ion transmembrane transport(GO:0071421)
1.3 3.9 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.3 3.8 GO:1904064 positive regulation of cation transmembrane transport(GO:1904064)
1.3 5.1 GO:0006942 regulation of striated muscle contraction(GO:0006942)
1.3 17.6 GO:0014047 glutamate secretion(GO:0014047)
1.3 13.8 GO:0007266 Rho protein signal transduction(GO:0007266)
1.3 10.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
1.3 23.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
1.3 10.0 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
1.3 5.0 GO:0002644 negative regulation of tolerance induction(GO:0002644)
1.2 1.2 GO:0045829 negative regulation of isotype switching(GO:0045829)
1.2 49.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
1.2 26.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
1.2 14.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.2 22.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
1.2 4.9 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
1.2 7.3 GO:0006768 biotin metabolic process(GO:0006768)
1.2 31.3 GO:0046710 GDP metabolic process(GO:0046710)
1.2 27.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
1.2 1.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
1.2 10.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
1.2 27.0 GO:0097502 mannosylation(GO:0097502)
1.2 25.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
1.2 1.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
1.2 10.4 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
1.2 2.3 GO:0003156 regulation of organ formation(GO:0003156)
1.2 11.5 GO:0031033 myosin filament organization(GO:0031033)
1.1 3.4 GO:0014735 regulation of muscle atrophy(GO:0014735)
1.1 2.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
1.1 11.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.1 2.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
1.1 17.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.1 3.3 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
1.1 1.1 GO:1905247 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
1.1 1.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
1.1 4.3 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
1.1 5.4 GO:0048278 vesicle docking(GO:0048278)
1.1 2.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
1.1 4.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.1 102.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.1 7.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
1.1 6.4 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
1.1 1.1 GO:0035963 cellular response to interleukin-13(GO:0035963)
1.1 1.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
1.1 2.1 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) response to interleukin-18(GO:0070673) cellular response to interleukin-18(GO:0071351)
1.0 2.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.0 4.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
1.0 17.3 GO:0008340 determination of adult lifespan(GO:0008340)
1.0 10.1 GO:0042461 photoreceptor cell development(GO:0042461)
1.0 18.2 GO:0019933 cAMP-mediated signaling(GO:0019933)
1.0 22.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.0 22.2 GO:0043506 regulation of JUN kinase activity(GO:0043506)
1.0 8.0 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
1.0 37.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
1.0 7.0 GO:0045026 plasma membrane fusion(GO:0045026)
1.0 3.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.0 3.0 GO:0042426 choline catabolic process(GO:0042426)
1.0 2.9 GO:0060087 negative regulation of smooth muscle contraction(GO:0045986) relaxation of vascular smooth muscle(GO:0060087)
1.0 3.9 GO:0071918 urea transmembrane transport(GO:0071918)
1.0 3.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
1.0 14.4 GO:0014003 oligodendrocyte development(GO:0014003)
1.0 2.9 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.0 19.1 GO:0031167 rRNA methylation(GO:0031167)
1.0 1.9 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.0 2.9 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.9 0.9 GO:0007635 chemosensory behavior(GO:0007635)
0.9 0.9 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.9 5.6 GO:0007000 nucleolus organization(GO:0007000)
0.9 2.8 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.9 0.9 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.9 0.9 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.9 4.6 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.9 9.3 GO:0044117 growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126)
0.9 2.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.9 4.6 GO:0001502 cartilage condensation(GO:0001502)
0.9 1.8 GO:0030047 actin modification(GO:0030047)
0.9 2.7 GO:0010872 regulation of cholesterol esterification(GO:0010872)
0.9 107.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.9 5.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.9 9.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.9 0.9 GO:0045686 negative regulation of glial cell differentiation(GO:0045686)
0.9 2.6 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.9 2.6 GO:0000023 maltose metabolic process(GO:0000023)
0.9 5.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.9 4.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.9 10.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.9 0.9 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.9 2.6 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.9 2.6 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.8 3.4 GO:0060482 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.8 8.3 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.8 2.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.8 11.6 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.8 9.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.8 8.0 GO:0097435 fibril organization(GO:0097435)
0.8 4.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.8 28.0 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.8 2.4 GO:0051004 regulation of lipoprotein lipase activity(GO:0051004)
0.8 2.4 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.8 2.4 GO:0015942 formate metabolic process(GO:0015942)
0.8 14.2 GO:0007340 acrosome reaction(GO:0007340)
0.8 7.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.8 9.2 GO:0006824 cobalt ion transport(GO:0006824)
0.8 0.8 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.7 9.0 GO:0045109 intermediate filament organization(GO:0045109)
0.7 2.2 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.7 2.2 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.7 1.5 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.7 4.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.7 2.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.7 1.5 GO:0032616 interleukin-13 production(GO:0032616)
0.7 7.3 GO:0034694 response to prostaglandin(GO:0034694)
0.7 1.4 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.7 1.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.7 4.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.7 7.9 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.7 2.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.7 4.9 GO:0034969 histone arginine methylation(GO:0034969)
0.7 19.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.7 0.7 GO:0070417 cellular response to cold(GO:0070417)
0.7 1.4 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.7 2.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.7 3.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.7 68.0 GO:0050953 sensory perception of light stimulus(GO:0050953)
0.7 14.1 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.7 24.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.7 30.5 GO:0007586 digestion(GO:0007586)
0.7 1.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.7 3.3 GO:0006013 mannose metabolic process(GO:0006013)
0.6 20.7 GO:0050909 sensory perception of taste(GO:0050909)
0.6 10.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.6 3.1 GO:0032202 telomere assembly(GO:0032202)
0.6 1.3 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.6 6.2 GO:0007632 visual behavior(GO:0007632)
0.6 2.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.6 18.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.6 3.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.6 1.2 GO:0051182 coenzyme transport(GO:0051182)
0.6 1.7 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.6 1.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.6 6.4 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.6 4.0 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.6 6.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.6 3.9 GO:2000811 negative regulation of anoikis(GO:2000811)
0.5 1.6 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.5 3.2 GO:0051026 chiasma assembly(GO:0051026)
0.5 9.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.5 2.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353) S-adenosylhomocysteine metabolic process(GO:0046498)
0.5 1.1 GO:0015824 proline transport(GO:0015824)
0.5 6.3 GO:0006833 water transport(GO:0006833)
0.5 2.6 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.5 1.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.5 5.2 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.5 0.5 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.5 1.5 GO:0010744 positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.5 1.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 2.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.5 0.5 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.5 1.0 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.5 2.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.5 1.0 GO:0007320 insemination(GO:0007320)
0.5 0.5 GO:0048539 bone marrow development(GO:0048539)
0.5 3.2 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.5 5.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.5 1.8 GO:1900271 regulation of long-term synaptic potentiation(GO:1900271)
0.5 2.3 GO:0048240 sperm capacitation(GO:0048240)
0.4 2.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.4 0.9 GO:1903378 positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.4 4.4 GO:0050919 negative chemotaxis(GO:0050919)
0.4 3.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4 153.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.4 1.7 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4 3.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.4 2.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.4 2.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 0.4 GO:0018879 biphenyl metabolic process(GO:0018879)
0.4 8.0 GO:0072337 modified amino acid transport(GO:0072337)
0.4 0.8 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.4 1.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.4 2.2 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.4 0.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.4 1.1 GO:0007135 meiosis II(GO:0007135) meiotic sister chromatid segregation(GO:0045144)
0.3 1.7 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.3 1.0 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.3 1.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 7.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 1.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.3 2.9 GO:0002251 organ or tissue specific immune response(GO:0002251)
0.3 0.3 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.3 0.6 GO:0002903 regulation of B cell apoptotic process(GO:0002902) negative regulation of B cell apoptotic process(GO:0002903)
0.3 2.6 GO:0015747 urate transport(GO:0015747)
0.3 0.9 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.3 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.3 6.8 GO:0032418 lysosome localization(GO:0032418)
0.3 1.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 18.0 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.3 1.7 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.3 0.8 GO:0002467 germinal center formation(GO:0002467)
0.3 1.6 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 2.9 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 1.7 GO:0072338 cellular lactam metabolic process(GO:0072338)
0.2 3.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 4.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 0.2 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 2.3 GO:0015695 organic cation transport(GO:0015695)
0.2 1.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 0.4 GO:0071838 cell proliferation in bone marrow(GO:0071838)
0.2 0.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 0.8 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.2 1.0 GO:0048806 genitalia development(GO:0048806)
0.2 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 0.4 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.2 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.2 0.5 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.2 0.3 GO:0035624 receptor transactivation(GO:0035624)
0.2 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 0.3 GO:0070842 aggresome assembly(GO:0070842)
0.1 12.4 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 1.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 11.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.1 1.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.2 GO:0032769 negative regulation of monooxygenase activity(GO:0032769)
0.1 0.4 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 2.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.1 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.1 0.3 GO:0032324 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 2.4 GO:0097485 neuron projection guidance(GO:0097485)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.3 GO:0007588 excretion(GO:0007588)
0.0 0.1 GO:0006972 hyperosmotic response(GO:0006972)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
53.0 211.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
49.9 199.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
44.3 132.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
43.0 257.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
31.8 31.8 GO:0019034 viral replication complex(GO:0019034)
31.5 94.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
26.7 133.5 GO:0072534 perineuronal net(GO:0072534)
25.9 103.6 GO:0070695 FHF complex(GO:0070695)
25.5 229.4 GO:0044327 dendritic spine head(GO:0044327)
25.5 152.8 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
24.6 98.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
23.0 46.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
22.4 67.1 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
22.1 66.3 GO:0060987 lipid tube(GO:0060987)
19.6 58.7 GO:0034455 t-UTP complex(GO:0034455)
19.5 19.5 GO:0005883 neurofilament(GO:0005883)
19.3 38.7 GO:0014802 terminal cisterna(GO:0014802)
18.7 112.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
18.7 411.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
18.7 56.0 GO:0016938 kinesin I complex(GO:0016938)
18.1 90.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
18.0 107.8 GO:0045298 tubulin complex(GO:0045298)
17.9 89.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
17.2 344.8 GO:0033270 paranode region of axon(GO:0033270)
16.5 49.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
16.0 63.9 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
15.9 47.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
15.8 252.1 GO:0097512 cardiac myofibril(GO:0097512)
15.7 15.7 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
15.6 77.9 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
15.5 139.8 GO:0033391 chromatoid body(GO:0033391)
15.4 200.3 GO:0043194 axon initial segment(GO:0043194)
14.6 58.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
14.5 43.4 GO:0043293 apoptosome(GO:0043293)
14.4 129.7 GO:1990761 growth cone lamellipodium(GO:1990761)
14.0 826.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
13.9 83.3 GO:0005927 muscle tendon junction(GO:0005927)
13.4 201.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
13.4 107.0 GO:0000138 Golgi trans cisterna(GO:0000138)
13.3 40.0 GO:0030991 intraciliary transport particle A(GO:0030991)
13.3 39.9 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
13.3 119.4 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
13.0 77.9 GO:0000137 Golgi cis cisterna(GO:0000137)
12.8 25.7 GO:0001939 female pronucleus(GO:0001939)
12.8 38.3 GO:0097224 sperm connecting piece(GO:0097224)
12.7 393.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
12.6 113.3 GO:0071953 elastic fiber(GO:0071953)
11.9 59.7 GO:0031673 H zone(GO:0031673)
11.8 23.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
11.7 163.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
11.5 172.9 GO:0032591 dendritic spine membrane(GO:0032591)
11.4 34.3 GO:0044609 DBIRD complex(GO:0044609)
11.4 57.1 GO:0032449 CBM complex(GO:0032449)
11.4 113.5 GO:0042583 chromaffin granule(GO:0042583)
11.3 34.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
11.2 55.9 GO:1990769 proximal neuron projection(GO:1990769)
11.1 33.4 GO:1990597 AIP1-IRE1 complex(GO:1990597)
11.0 88.0 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
11.0 33.0 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
10.8 107.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
10.7 64.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
10.7 53.6 GO:0045160 myosin I complex(GO:0045160)
10.5 42.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
10.2 71.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
10.2 10.2 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
10.2 71.5 GO:1990130 Iml1 complex(GO:1990130)
10.1 60.4 GO:0070382 exocytic vesicle(GO:0070382)
10.1 20.1 GO:0044294 dendritic growth cone(GO:0044294)
9.9 19.9 GO:0044308 axonal spine(GO:0044308)
9.9 89.2 GO:0035253 ciliary rootlet(GO:0035253)
9.7 106.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
9.6 57.8 GO:0033269 internode region of axon(GO:0033269)
9.6 134.8 GO:0043083 synaptic cleft(GO:0043083)
9.6 28.7 GO:0055028 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
9.5 47.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
9.5 57.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
9.4 66.0 GO:0097418 neurofibrillary tangle(GO:0097418)
9.1 54.9 GO:0045211 postsynaptic membrane(GO:0045211)
9.1 145.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
9.1 36.3 GO:0097165 nuclear stress granule(GO:0097165)
9.0 215.2 GO:0044295 axonal growth cone(GO:0044295)
8.9 160.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
8.9 80.4 GO:0097427 microtubule bundle(GO:0097427)
8.9 230.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
8.8 672.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
8.8 35.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
8.7 542.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
8.6 164.3 GO:0097386 glial cell projection(GO:0097386)
8.6 68.9 GO:0043203 axon hillock(GO:0043203)
8.6 94.5 GO:0032593 insulin-responsive compartment(GO:0032593)
8.6 8.6 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
8.4 25.2 GO:0036398 TCR signalosome(GO:0036398)
8.4 134.0 GO:0035102 PRC1 complex(GO:0035102)
8.3 8.3 GO:0002139 stereocilia coupling link(GO:0002139)
8.3 33.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
8.3 24.9 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
8.3 8.3 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
8.2 24.5 GO:0071439 clathrin complex(GO:0071439)
8.1 347.8 GO:0048786 presynaptic active zone(GO:0048786)
7.9 23.8 GO:0098536 deuterosome(GO:0098536)
7.7 100.0 GO:0031045 dense core granule(GO:0031045)
7.7 352.7 GO:0097546 ciliary base(GO:0097546)
7.5 60.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
7.5 22.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
7.3 29.3 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
7.3 65.9 GO:0031209 SCAR complex(GO:0031209)
7.3 21.8 GO:0097229 sperm end piece(GO:0097229)
7.2 65.1 GO:0097208 alveolar lamellar body(GO:0097208)
7.2 100.9 GO:0032590 dendrite membrane(GO:0032590)
7.2 100.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
7.2 28.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
7.1 85.1 GO:0016013 syntrophin complex(GO:0016013)
7.0 224.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
7.0 70.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
6.9 34.7 GO:0070847 core mediator complex(GO:0070847)
6.8 27.2 GO:1990879 CST complex(GO:1990879)
6.8 20.3 GO:1990909 Wnt signalosome(GO:1990909)
6.8 13.5 GO:0034657 GID complex(GO:0034657)
6.7 13.3 GO:0032426 stereocilium tip(GO:0032426)
6.7 33.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
6.6 205.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
6.6 457.5 GO:0042734 presynaptic membrane(GO:0042734)
6.6 119.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
6.6 52.8 GO:0005593 FACIT collagen trimer(GO:0005593)
6.6 111.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
6.6 19.7 GO:0035189 Rb-E2F complex(GO:0035189)
6.5 19.4 GO:0034706 sodium channel complex(GO:0034706)
6.5 64.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
6.5 19.4 GO:0097443 sorting endosome(GO:0097443)
6.4 83.7 GO:0097433 dense body(GO:0097433)
6.4 83.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
6.3 742.3 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
6.3 31.7 GO:0033010 paranodal junction(GO:0033010)
6.3 37.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
6.3 44.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
6.3 69.4 GO:0005955 calcineurin complex(GO:0005955)
6.2 25.0 GO:0030893 meiotic cohesin complex(GO:0030893)
6.2 37.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
6.2 24.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
6.1 67.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
6.1 24.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
6.1 429.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
6.0 24.0 GO:0016461 unconventional myosin complex(GO:0016461)
5.8 69.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
5.8 5.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
5.7 11.5 GO:0071546 pi-body(GO:0071546)
5.7 280.6 GO:0043198 dendritic shaft(GO:0043198)
5.7 11.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
5.7 56.8 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
5.7 39.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
5.6 67.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
5.6 33.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
5.4 65.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
5.4 10.8 GO:0032584 growth cone membrane(GO:0032584)
5.4 1258.5 GO:0060076 excitatory synapse(GO:0060076)
5.4 383.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
5.4 64.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
5.3 37.2 GO:0036021 endolysosome lumen(GO:0036021)
5.3 21.2 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
5.2 10.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
5.2 67.8 GO:0030478 actin cap(GO:0030478)
5.2 46.9 GO:0005614 interstitial matrix(GO:0005614)
5.2 15.6 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
5.2 56.8 GO:0098651 basement membrane collagen trimer(GO:0098651)
5.1 40.8 GO:0072487 MSL complex(GO:0072487)
5.1 50.8 GO:0008091 spectrin(GO:0008091)
5.0 196.7 GO:0001750 photoreceptor outer segment(GO:0001750)
5.0 10.1 GO:0016939 kinesin II complex(GO:0016939)
5.0 15.0 GO:0031933 telomeric heterochromatin(GO:0031933)
5.0 15.0 GO:0005899 insulin receptor complex(GO:0005899)
5.0 164.6 GO:0001917 photoreceptor inner segment(GO:0001917)
4.9 14.6 GO:0031251 PAN complex(GO:0031251)
4.8 842.9 GO:0098793 presynapse(GO:0098793)
4.8 19.1 GO:0031258 lamellipodium membrane(GO:0031258)
4.7 18.9 GO:0005602 complement component C1 complex(GO:0005602)
4.7 28.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
4.7 4.7 GO:0099634 postsynaptic specialization membrane(GO:0099634)
4.6 18.4 GO:0060077 inhibitory synapse(GO:0060077)
4.6 308.2 GO:0005581 collagen trimer(GO:0005581)
4.6 23.0 GO:0097513 myosin II filament(GO:0097513)
4.6 109.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
4.6 27.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
4.5 144.8 GO:0060170 ciliary membrane(GO:0060170)
4.4 13.3 GO:0033268 node of Ranvier(GO:0033268)
4.4 492.7 GO:0005796 Golgi lumen(GO:0005796)
4.4 17.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
4.3 17.4 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
4.3 21.7 GO:0017119 Golgi transport complex(GO:0017119)
4.3 21.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
4.3 21.4 GO:0032302 MutSbeta complex(GO:0032302)
4.3 327.9 GO:0036064 ciliary basal body(GO:0036064)
4.2 20.9 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
4.2 41.5 GO:0045180 basal cortex(GO:0045180)
4.1 256.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
4.1 16.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
4.1 8.2 GO:1990393 3M complex(GO:1990393)
4.1 73.1 GO:0005922 connexon complex(GO:0005922)
4.0 16.2 GO:0035363 histone locus body(GO:0035363)
4.0 28.2 GO:1990745 EARP complex(GO:1990745)
3.9 54.4 GO:0000800 lateral element(GO:0000800)
3.8 7.6 GO:0000805 X chromosome(GO:0000805)
3.7 14.9 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
3.7 3.7 GO:0036020 endolysosome membrane(GO:0036020)
3.7 128.4 GO:0005905 clathrin-coated pit(GO:0005905)
3.6 40.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
3.6 39.6 GO:0002116 semaphorin receptor complex(GO:0002116)
3.6 21.6 GO:0031527 filopodium membrane(GO:0031527)
3.6 17.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
3.5 77.5 GO:0042627 chylomicron(GO:0042627)
3.5 945.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
3.4 34.5 GO:0046581 intercellular canaliculus(GO:0046581)
3.4 291.9 GO:0043204 perikaryon(GO:0043204)
3.4 10.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
3.4 16.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
3.4 70.5 GO:0009925 basal plasma membrane(GO:0009925)
3.3 10.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
3.3 23.3 GO:0042599 lamellar body(GO:0042599)
3.2 19.5 GO:0001940 male pronucleus(GO:0001940)
3.2 9.7 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
3.2 19.3 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
3.2 12.7 GO:0031310 intrinsic component of vacuolar membrane(GO:0031310)
3.1 40.5 GO:0031594 neuromuscular junction(GO:0031594)
3.1 9.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
3.0 69.8 GO:0032589 neuron projection membrane(GO:0032589)
3.0 27.1 GO:0042587 glycogen granule(GO:0042587)
3.0 44.8 GO:0097225 sperm midpiece(GO:0097225)
3.0 29.5 GO:0030061 mitochondrial crista(GO:0030061)
2.9 99.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
2.9 114.2 GO:0005859 muscle myosin complex(GO:0005859)
2.8 238.4 GO:0005814 centriole(GO:0005814)
2.8 90.6 GO:0016235 aggresome(GO:0016235)
2.8 5.7 GO:0005760 gamma DNA polymerase complex(GO:0005760)
2.8 5.6 GO:0043291 RAVE complex(GO:0043291)
2.8 608.1 GO:0016323 basolateral plasma membrane(GO:0016323)
2.7 131.1 GO:0005801 cis-Golgi network(GO:0005801)
2.7 16.3 GO:0032009 early phagosome(GO:0032009)
2.7 16.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
2.6 23.7 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
2.6 13.0 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
2.5 22.7 GO:0042788 polysomal ribosome(GO:0042788)
2.5 10.0 GO:0060091 kinocilium(GO:0060091)
2.5 15.0 GO:0097440 apical dendrite(GO:0097440)
2.5 7.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
2.5 64.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
2.4 2.4 GO:0032839 dendrite cytoplasm(GO:0032839)
2.4 28.9 GO:0000145 exocyst(GO:0000145)
2.4 16.8 GO:0098845 postsynaptic endosome(GO:0098845)
2.4 23.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.4 35.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
2.4 23.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
2.3 20.7 GO:0000813 ESCRT I complex(GO:0000813)
2.3 329.3 GO:0005802 trans-Golgi network(GO:0005802)
2.3 13.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
2.3 54.9 GO:0030057 desmosome(GO:0030057)
2.3 222.5 GO:0030426 growth cone(GO:0030426)
2.2 4.5 GO:0031905 early endosome lumen(GO:0031905)
2.2 2.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
2.2 15.2 GO:0036157 outer dynein arm(GO:0036157)
2.2 15.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
2.2 6.5 GO:0032116 SMC loading complex(GO:0032116)
2.2 51.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
2.1 113.0 GO:0055037 recycling endosome(GO:0055037)
2.1 10.5 GO:0035686 sperm fibrous sheath(GO:0035686)
2.0 55.2 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
2.0 33.7 GO:0035631 CD40 receptor complex(GO:0035631)
2.0 33.6 GO:0031082 BLOC complex(GO:0031082)
2.0 3.9 GO:0005965 protein farnesyltransferase complex(GO:0005965)
2.0 7.8 GO:0002177 manchette(GO:0002177)
2.0 9.8 GO:0030427 site of polarized growth(GO:0030427)
1.9 1.9 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
1.9 46.5 GO:1904115 axon cytoplasm(GO:1904115)
1.9 9.6 GO:0032807 DNA ligase IV complex(GO:0032807)
1.9 86.3 GO:0005902 microvillus(GO:0005902)
1.8 7.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.8 5.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.8 19.8 GO:0030870 Mre11 complex(GO:0030870)
1.8 7.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.8 5.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
1.7 49.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
1.7 218.0 GO:0043025 neuronal cell body(GO:0043025)
1.7 50.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
1.7 8.5 GO:0071141 SMAD protein complex(GO:0071141)
1.7 205.8 GO:0031225 anchored component of membrane(GO:0031225)
1.7 10.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.7 360.9 GO:0043235 receptor complex(GO:0043235)
1.7 13.3 GO:0044447 axoneme part(GO:0044447)
1.7 18.2 GO:0000974 Prp19 complex(GO:0000974)
1.6 6214.0 GO:0016021 integral component of membrane(GO:0016021)
1.6 9.7 GO:0070545 PeBoW complex(GO:0070545)
1.6 11.1 GO:0002080 acrosomal membrane(GO:0002080)
1.5 4.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.5 3.0 GO:0043159 acrosomal matrix(GO:0043159)
1.5 11.8 GO:0071437 invadopodium(GO:0071437)
1.5 4.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.5 1.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
1.5 16.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.4 7.2 GO:0032444 activin responsive factor complex(GO:0032444)
1.4 22.4 GO:0001772 immunological synapse(GO:0001772)
1.3 14.4 GO:0000242 pericentriolar material(GO:0000242)
1.3 35.7 GO:0016459 myosin complex(GO:0016459)
1.3 5.1 GO:0001739 sex chromatin(GO:0001739)
1.2 17.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
1.2 54.1 GO:0045171 intercellular bridge(GO:0045171)
1.2 2.4 GO:0036038 MKS complex(GO:0036038)
1.2 1.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
1.2 4.6 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
1.1 2.3 GO:0042588 zymogen granule(GO:0042588)
1.1 3.3 GO:0033267 axon part(GO:0033267)
1.1 72.6 GO:0009897 external side of plasma membrane(GO:0009897)
1.0 6.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
1.0 1.0 GO:0061689 tricellular tight junction(GO:0061689)
1.0 3.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.9 8.9 GO:0070552 BRISC complex(GO:0070552)
0.8 48.6 GO:0016324 apical plasma membrane(GO:0016324)
0.8 4.0 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.8 5.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.8 11.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.8 1.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.8 10.8 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.7 2.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.7 10.6 GO:0045177 apical part of cell(GO:0045177)
0.7 2.0 GO:0000801 central element(GO:0000801)
0.6 46.9 GO:0005770 late endosome(GO:0005770)
0.6 3.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.6 2.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 2.0 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.5 6.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 5.0 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 0.6 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.3 3.2 GO:0061574 ASAP complex(GO:0061574)
0.3 0.9 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3 9.4 GO:0016592 mediator complex(GO:0016592)
0.3 1.0 GO:1990423 RZZ complex(GO:1990423)
0.3 3.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.6 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2 1.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 1.1 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.1 0.1 GO:0031526 brush border membrane(GO:0031526)
0.1 0.1 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.1 0.8 GO:0031904 endosome lumen(GO:0031904)
0.1 3.3 GO:0000792 heterochromatin(GO:0000792)
0.1 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0045178 basal part of cell(GO:0045178)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
84.6 338.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
53.8 269.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
53.0 211.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
50.2 200.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
43.6 174.5 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
41.4 124.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
34.3 137.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
33.8 33.8 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
32.2 96.5 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
30.7 122.7 GO:0097001 ceramide binding(GO:0097001)
30.1 90.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
30.0 90.0 GO:0031696 alpha-2C adrenergic receptor binding(GO:0031696)
29.9 29.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
29.7 148.6 GO:0004803 transposase activity(GO:0004803)
29.0 115.9 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
29.0 86.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
28.8 115.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
28.1 84.4 GO:0032093 SAM domain binding(GO:0032093)
27.6 110.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
26.7 80.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
26.2 105.0 GO:0004773 steryl-sulfatase activity(GO:0004773)
25.3 101.0 GO:0035939 microsatellite binding(GO:0035939)
24.6 24.6 GO:0097677 STAT family protein binding(GO:0097677)
23.7 71.2 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
23.0 68.9 GO:0061697 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
22.9 91.6 GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
22.0 110.2 GO:0070097 delta-catenin binding(GO:0070097)
22.0 197.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
21.6 108.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
21.1 63.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
20.8 62.5 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
19.7 236.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
19.4 77.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
19.0 94.8 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
18.9 132.6 GO:0015252 hydrogen ion channel activity(GO:0015252)
18.7 56.0 GO:0031687 A2A adenosine receptor binding(GO:0031687)
18.4 147.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
18.0 53.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
17.9 53.7 GO:0016497 substance K receptor activity(GO:0016497)
17.8 53.4 GO:0052835 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
17.7 53.0 GO:0050254 rhodopsin kinase activity(GO:0050254)
17.3 156.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
17.3 190.3 GO:0032051 clathrin light chain binding(GO:0032051)
17.2 68.7 GO:0032184 SUMO polymer binding(GO:0032184)
17.1 51.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
17.1 68.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
17.0 136.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
17.0 101.7 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
16.9 135.4 GO:0004111 creatine kinase activity(GO:0004111)
16.7 100.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
16.4 81.8 GO:0070051 fibrinogen binding(GO:0070051)
16.3 65.1 GO:0005163 nerve growth factor receptor binding(GO:0005163)
16.1 48.3 GO:0031849 olfactory receptor binding(GO:0031849)
16.0 802.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
16.0 112.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
16.0 144.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
16.0 63.9 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
15.7 485.6 GO:0017075 syntaxin-1 binding(GO:0017075)
15.6 31.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
15.6 77.9 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
15.5 31.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
15.5 93.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
15.5 61.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
15.3 230.2 GO:0005344 oxygen transporter activity(GO:0005344)
15.2 121.5 GO:0098821 BMP receptor activity(GO:0098821)
15.1 287.4 GO:0031005 filamin binding(GO:0031005)
15.0 179.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
14.7 58.8 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
14.6 393.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
14.4 57.5 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
14.3 57.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
14.3 71.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
14.3 42.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
14.1 84.8 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
14.0 84.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
14.0 41.9 GO:0033142 progesterone receptor binding(GO:0033142)
13.9 41.7 GO:0030350 iron-responsive element binding(GO:0030350)
13.8 180.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
13.8 55.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
13.5 40.5 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
13.3 53.4 GO:0001626 nociceptin receptor activity(GO:0001626)
13.3 40.0 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
13.3 173.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
13.2 52.8 GO:0031716 calcitonin receptor binding(GO:0031716)
13.2 92.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
13.1 197.2 GO:0008179 adenylate cyclase binding(GO:0008179)
13.1 39.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
13.1 39.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
12.7 63.6 GO:0052841 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
12.7 50.6 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
12.6 113.4 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
12.2 36.5 GO:0045499 chemorepellent activity(GO:0045499)
12.2 48.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
12.1 194.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
12.1 36.4 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
12.0 71.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
11.9 155.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
11.9 47.6 GO:0004341 gluconolactonase activity(GO:0004341)
11.9 59.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
11.8 59.0 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
11.7 93.6 GO:0015235 cobalamin transporter activity(GO:0015235)
11.6 23.3 GO:0051379 epinephrine binding(GO:0051379)
11.5 115.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
11.4 45.8 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
11.4 171.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
11.4 34.1 GO:0052811 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811)
11.2 101.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
11.2 67.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
11.2 189.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
11.2 33.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
11.1 44.6 GO:0019770 IgG receptor activity(GO:0019770)
11.0 55.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
11.0 77.0 GO:0008172 S-methyltransferase activity(GO:0008172)
11.0 33.0 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
11.0 65.9 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
10.9 54.7 GO:0043237 laminin-1 binding(GO:0043237)
10.9 21.8 GO:0033691 sialic acid binding(GO:0033691)
10.9 21.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
10.9 65.2 GO:0003998 acylphosphatase activity(GO:0003998)
10.8 249.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
10.8 151.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
10.7 53.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
10.6 85.0 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
10.6 31.7 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
10.5 21.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
10.5 31.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
10.5 31.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
10.5 428.7 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
10.4 511.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
10.3 51.5 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
10.2 51.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
10.2 71.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
10.2 91.7 GO:0016015 morphogen activity(GO:0016015)
10.0 120.3 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
10.0 60.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
10.0 29.9 GO:0005502 11-cis retinal binding(GO:0005502)
9.8 333.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
9.8 39.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
9.8 136.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
9.7 29.2 GO:0033749 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
9.7 19.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
9.7 77.2 GO:0038064 collagen receptor activity(GO:0038064)
9.5 85.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
9.5 85.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
9.5 85.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
9.4 301.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
9.4 65.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
9.3 55.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
9.2 27.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
9.1 209.2 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
9.1 54.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
9.0 9.0 GO:0008556 potassium-transporting ATPase activity(GO:0008556)
9.0 44.9 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
9.0 80.8 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
8.9 26.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
8.9 53.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
8.9 124.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
8.9 106.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
8.8 35.3 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
8.8 52.9 GO:0061665 SUMO ligase activity(GO:0061665)
8.8 175.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
8.7 43.5 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
8.7 78.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
8.7 26.0 GO:0045322 unmethylated CpG binding(GO:0045322)
8.5 179.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
8.5 68.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
8.5 50.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
8.4 83.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
8.3 58.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
8.3 33.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
8.2 24.7 GO:0070984 SET domain binding(GO:0070984)
8.2 41.1 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
8.2 500.4 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
8.2 41.0 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
8.1 40.7 GO:0070573 metallodipeptidase activity(GO:0070573)
8.1 24.4 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
8.0 72.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
8.0 16.0 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
8.0 136.0 GO:0070411 I-SMAD binding(GO:0070411)
8.0 183.3 GO:0030552 cAMP binding(GO:0030552)
7.9 23.8 GO:0035473 lipase binding(GO:0035473)
7.9 79.2 GO:0051011 microtubule minus-end binding(GO:0051011)
7.9 31.5 GO:0004461 lactose synthase activity(GO:0004461)
7.8 78.5 GO:0008131 primary amine oxidase activity(GO:0008131)
7.7 38.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
7.7 23.2 GO:0008431 vitamin E binding(GO:0008431)
7.7 46.2 GO:0004935 adrenergic receptor activity(GO:0004935)
7.7 100.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
7.7 184.5 GO:0070300 phosphatidic acid binding(GO:0070300)
7.7 99.7 GO:0070700 BMP receptor binding(GO:0070700)
7.6 30.5 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
7.6 68.4 GO:0004969 histamine receptor activity(GO:0004969)
7.6 15.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
7.5 37.5 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
7.5 142.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
7.4 52.0 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
7.3 219.0 GO:0017147 Wnt-protein binding(GO:0017147)
7.3 21.9 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
7.3 87.5 GO:0004075 biotin carboxylase activity(GO:0004075)
7.3 123.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
7.3 21.9 GO:0005174 CD40 receptor binding(GO:0005174)
7.3 7.3 GO:0035276 ethanol binding(GO:0035276)
7.3 203.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
7.3 108.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
7.3 181.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
7.2 43.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
7.2 79.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
7.2 28.9 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
7.2 122.8 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
7.2 57.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
7.2 215.7 GO:0005212 structural constituent of eye lens(GO:0005212)
7.1 128.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
7.1 35.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
7.1 169.5 GO:0043274 phospholipase binding(GO:0043274)
7.0 21.0 GO:0005484 SNAP receptor activity(GO:0005484)
7.0 41.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
7.0 20.9 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
6.9 13.9 GO:0043199 sulfate binding(GO:0043199)
6.9 27.7 GO:0004925 prolactin receptor activity(GO:0004925)
6.9 165.7 GO:0001223 transcription coactivator binding(GO:0001223)
6.9 68.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
6.8 13.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
6.8 40.7 GO:0039552 RIG-I binding(GO:0039552)
6.8 54.2 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
6.8 87.8 GO:0019841 retinol binding(GO:0019841)
6.8 27.0 GO:0099609 microtubule lateral binding(GO:0099609)
6.7 26.9 GO:0038132 neuregulin binding(GO:0038132)
6.7 13.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
6.7 20.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
6.7 336.1 GO:0017080 sodium channel regulator activity(GO:0017080)
6.7 73.7 GO:0004383 guanylate cyclase activity(GO:0004383)
6.7 20.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
6.7 93.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
6.6 26.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
6.6 33.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
6.6 19.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
6.6 138.3 GO:0005112 Notch binding(GO:0005112)
6.6 32.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
6.5 78.5 GO:0046870 cadmium ion binding(GO:0046870)
6.5 6.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
6.5 71.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
6.5 32.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
6.5 39.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
6.5 51.8 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
6.4 51.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
6.4 32.2 GO:0000150 recombinase activity(GO:0000150)
6.4 19.3 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
6.4 179.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
6.4 63.8 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
6.3 31.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
6.3 6.3 GO:0030226 apolipoprotein receptor activity(GO:0030226)
6.3 18.9 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
6.3 31.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
6.3 6.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
6.2 31.1 GO:0004994 somatostatin receptor activity(GO:0004994)
6.2 24.6 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
6.2 73.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
6.2 24.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
6.1 18.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
6.1 49.0 GO:0097642 calcitonin family receptor activity(GO:0097642)
6.1 55.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
6.1 6.1 GO:0071837 HMG box domain binding(GO:0071837)
6.1 103.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
6.1 709.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
6.1 24.2 GO:0047708 biotinidase activity(GO:0047708)
6.1 48.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
6.1 30.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
6.0 18.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
6.0 18.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
6.0 84.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
6.0 60.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
6.0 42.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
5.9 11.8 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
5.8 5.8 GO:0034056 estrogen response element binding(GO:0034056)
5.8 52.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
5.8 34.9 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
5.8 11.6 GO:0035325 Toll-like receptor binding(GO:0035325)
5.8 133.1 GO:0031489 myosin V binding(GO:0031489)
5.8 34.7 GO:0048495 Roundabout binding(GO:0048495)
5.8 17.3 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
5.8 17.3 GO:0042731 PH domain binding(GO:0042731)
5.8 86.3 GO:0015250 water channel activity(GO:0015250)
5.7 40.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
5.7 17.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
5.7 28.3 GO:0097016 L27 domain binding(GO:0097016)
5.7 5.7 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
5.7 22.6 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
5.6 45.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
5.6 16.9 GO:0042954 lipoprotein transporter activity(GO:0042954)
5.6 16.8 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
5.6 16.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
5.6 27.9 GO:0004370 glycerol kinase activity(GO:0004370)
5.6 277.6 GO:0030507 spectrin binding(GO:0030507)
5.5 160.9 GO:0043015 gamma-tubulin binding(GO:0043015)
5.5 22.2 GO:0086077 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
5.5 33.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
5.5 27.5 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
5.5 16.5 GO:0005137 interleukin-5 receptor binding(GO:0005137)
5.5 11.0 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
5.5 98.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
5.4 65.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
5.4 27.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
5.4 26.9 GO:0016841 ammonia-lyase activity(GO:0016841)
5.3 74.8 GO:0015368 calcium:cation antiporter activity(GO:0015368)
5.3 53.3 GO:0045294 alpha-catenin binding(GO:0045294)
5.3 47.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
5.3 37.0 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
5.2 63.0 GO:0050811 GABA receptor binding(GO:0050811)
5.2 31.4 GO:0070728 leucine binding(GO:0070728)
5.2 36.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
5.2 15.6 GO:0017129 triglyceride binding(GO:0017129)
5.2 88.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
5.2 25.9 GO:0045504 dynein heavy chain binding(GO:0045504)
5.2 20.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
5.1 142.1 GO:0097109 neuroligin family protein binding(GO:0097109)
5.1 177.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
5.1 40.5 GO:0019215 intermediate filament binding(GO:0019215)
5.0 70.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
5.0 20.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
5.0 5.0 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
5.0 15.0 GO:0070735 protein-glycine ligase activity(GO:0070735)
5.0 169.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
5.0 44.6 GO:0048406 nerve growth factor binding(GO:0048406)
5.0 39.6 GO:0004017 adenylate kinase activity(GO:0004017)
5.0 14.9 GO:0004967 glucagon receptor activity(GO:0004967)
4.9 24.7 GO:0004522 ribonuclease A activity(GO:0004522)
4.9 14.7 GO:0031862 prostanoid receptor binding(GO:0031862)
4.9 24.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
4.9 14.6 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
4.9 4.9 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
4.8 4.8 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
4.8 28.9 GO:0004359 glutaminase activity(GO:0004359)
4.8 28.7 GO:0030172 troponin C binding(GO:0030172)
4.8 14.3 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
4.7 23.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
4.7 14.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
4.7 61.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
4.7 42.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
4.7 112.8 GO:0050780 dopamine receptor binding(GO:0050780)
4.7 28.0 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
4.7 84.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
4.7 23.3 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
4.6 110.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
4.6 4.6 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
4.6 259.9 GO:0070412 R-SMAD binding(GO:0070412)
4.5 4.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
4.5 86.3 GO:0051010 microtubule plus-end binding(GO:0051010)
4.5 13.6 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
4.5 22.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
4.5 18.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
4.5 31.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
4.4 31.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
4.4 31.1 GO:0001515 opioid peptide activity(GO:0001515)
4.4 4.4 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
4.4 48.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
4.4 30.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
4.4 17.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
4.4 17.5 GO:0008046 axon guidance receptor activity(GO:0008046)
4.4 39.3 GO:0004565 beta-galactosidase activity(GO:0004565)
4.4 43.6 GO:0004065 arylsulfatase activity(GO:0004065)
4.3 21.7 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
4.3 39.0 GO:0050682 AF-2 domain binding(GO:0050682)
4.3 68.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
4.3 25.6 GO:0004882 androgen receptor activity(GO:0004882)
4.3 255.6 GO:0001540 beta-amyloid binding(GO:0001540)
4.3 8.5 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
4.2 25.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
4.2 46.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
4.2 29.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
4.2 29.5 GO:0031705 bombesin receptor binding(GO:0031705)
4.2 25.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
4.2 21.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
4.2 218.7 GO:0022843 voltage-gated cation channel activity(GO:0022843)
4.2 12.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662) Toll-like receptor 2 binding(GO:0035663)
4.2 21.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
4.2 75.1 GO:0005003 ephrin receptor activity(GO:0005003)
4.2 16.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
4.2 29.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
4.1 20.7 GO:0043546 molybdopterin cofactor binding(GO:0043546)
4.1 33.0 GO:0051787 misfolded protein binding(GO:0051787)
4.1 82.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
4.1 275.5 GO:0019905 syntaxin binding(GO:0019905)
4.1 12.3 GO:0036505 prosaposin receptor activity(GO:0036505)
4.1 65.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
4.1 4.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
4.1 20.4 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
4.1 32.6 GO:0015232 heme transporter activity(GO:0015232)
4.1 28.5 GO:0055102 lipase inhibitor activity(GO:0055102)
4.0 52.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
4.0 8.0 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
4.0 16.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
4.0 40.1 GO:0042923 neuropeptide binding(GO:0042923)
4.0 8.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
4.0 95.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
4.0 4.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
3.9 15.7 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
3.9 23.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
3.9 19.5 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
3.9 73.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
3.9 11.6 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
3.9 46.4 GO:0008432 JUN kinase binding(GO:0008432)
3.9 23.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
3.9 15.4 GO:0008142 oxysterol binding(GO:0008142)
3.9 42.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
3.8 19.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
3.8 319.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
3.8 42.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
3.8 80.7 GO:0003785 actin monomer binding(GO:0003785)
3.8 11.5 GO:0008502 melatonin receptor activity(GO:0008502)
3.8 19.1 GO:0008410 CoA-transferase activity(GO:0008410)
3.8 11.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
3.8 248.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
3.8 11.3 GO:0017081 chloride channel regulator activity(GO:0017081)
3.8 30.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
3.7 108.5 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
3.7 70.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
3.7 52.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
3.7 14.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
3.7 63.0 GO:0009881 photoreceptor activity(GO:0009881)
3.7 11.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
3.7 11.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) quaternary ammonium group transmembrane transporter activity(GO:0015651)
3.7 59.3 GO:0043522 leucine zipper domain binding(GO:0043522)
3.7 122.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
3.7 114.5 GO:0046875 ephrin receptor binding(GO:0046875)
3.7 18.4 GO:0001594 trace-amine receptor activity(GO:0001594)
3.6 47.4 GO:0043014 alpha-tubulin binding(GO:0043014)
3.6 18.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
3.6 25.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
3.6 14.5 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
3.6 43.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
3.6 53.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
3.6 7.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
3.5 31.8 GO:0016594 glycine binding(GO:0016594)
3.5 115.2 GO:0003777 microtubule motor activity(GO:0003777)
3.5 7.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
3.5 104.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
3.5 6.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
3.5 114.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
3.4 72.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
3.4 6.9 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
3.4 10.2 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
3.4 13.6 GO:0097108 hedgehog family protein binding(GO:0097108)
3.4 13.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
3.4 30.6 GO:0005243 gap junction channel activity(GO:0005243)
3.4 13.6 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
3.4 20.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
3.4 10.1 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
3.3 16.5 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
3.3 9.9 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
3.3 19.7 GO:0043426 MRF binding(GO:0043426)
3.3 13.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
3.3 19.5 GO:0097322 7SK snRNA binding(GO:0097322)
3.2 55.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
3.2 12.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
3.2 9.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
3.2 48.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
3.2 22.3 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
3.2 6.4 GO:0010851 cyclase regulator activity(GO:0010851)
3.2 19.0 GO:0034711 inhibin binding(GO:0034711)
3.2 25.4 GO:0042043 neurexin family protein binding(GO:0042043)
3.2 15.8 GO:0016918 retinal binding(GO:0016918)
3.2 12.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
3.1 62.3 GO:0005522 profilin binding(GO:0005522)
3.1 27.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
3.1 6.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
3.1 15.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
3.1 12.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
3.0 21.1 GO:1903136 cuprous ion binding(GO:1903136)
3.0 18.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
3.0 12.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
3.0 9.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
3.0 11.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
3.0 14.9 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
3.0 8.9 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
3.0 14.8 GO:0030553 cGMP-dependent protein kinase activity(GO:0004692) cGMP binding(GO:0030553)
2.9 26.4 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
2.9 8.8 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
2.9 20.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
2.9 20.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
2.9 17.2 GO:0017040 ceramidase activity(GO:0017040)
2.9 31.5 GO:0032036 myosin heavy chain binding(GO:0032036)
2.9 14.3 GO:0051525 NFAT protein binding(GO:0051525)
2.9 17.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
2.8 324.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
2.8 8.5 GO:0002046 opsin binding(GO:0002046)
2.8 14.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
2.8 14.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
2.8 50.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
2.8 38.8 GO:0031996 thioesterase binding(GO:0031996)
2.8 13.8 GO:0070061 fructose binding(GO:0070061)
2.8 27.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
2.8 33.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
2.8 8.3 GO:0008384 IkappaB kinase activity(GO:0008384)
2.8 41.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
2.7 60.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
2.7 10.9 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
2.7 2.7 GO:0004016 adenylate cyclase activity(GO:0004016)
2.7 10.9 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
2.7 18.6 GO:0032027 myosin light chain binding(GO:0032027)
2.6 13.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
2.6 29.0 GO:0015643 toxic substance binding(GO:0015643)
2.6 2.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
2.6 47.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
2.6 33.9 GO:0008066 glutamate receptor activity(GO:0008066)
2.6 7.8 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
2.6 18.1 GO:0034235 GPI anchor binding(GO:0034235)
2.6 41.3 GO:0022839 ion gated channel activity(GO:0022839)
2.6 10.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
2.6 28.1 GO:0017154 semaphorin receptor activity(GO:0017154)
2.6 43.5 GO:0015145 monosaccharide transmembrane transporter activity(GO:0015145)
2.6 311.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
2.5 17.8 GO:0004797 thymidine kinase activity(GO:0004797)
2.5 12.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
2.5 7.6 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
2.5 190.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
2.5 10.0 GO:0015057 thrombin receptor activity(GO:0015057)
2.5 12.4 GO:0050816 phosphothreonine binding(GO:0050816)
2.5 17.3 GO:0045159 myosin II binding(GO:0045159)
2.5 4.9 GO:0031893 vasopressin receptor binding(GO:0031893)
2.4 52.6 GO:0042166 acetylcholine binding(GO:0042166)
2.3 9.4 GO:0034040 lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041)
2.3 32.8 GO:0050321 tau-protein kinase activity(GO:0050321)
2.3 13.9 GO:0008420 CTD phosphatase activity(GO:0008420)
2.3 59.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
2.3 57.0 GO:0005109 frizzled binding(GO:0005109)
2.3 11.3 GO:0048185 activin binding(GO:0048185)
2.3 15.9 GO:0045545 syndecan binding(GO:0045545)
2.3 6.8 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
2.3 9.0 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)
2.2 11.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
2.2 13.3 GO:0004046 aminoacylase activity(GO:0004046)
2.2 6.6 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
2.2 8.8 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
2.2 35.1 GO:0070840 dynein complex binding(GO:0070840)
2.2 217.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
2.2 8.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
2.2 43.8 GO:0004806 triglyceride lipase activity(GO:0004806)
2.2 88.3 GO:0015085 calcium ion transmembrane transporter activity(GO:0015085)
2.2 17.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
2.1 2.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
2.1 6.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
2.1 62.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
2.1 8.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
2.1 18.6 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
2.0 12.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.0 6.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
2.0 60.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
2.0 14.2 GO:0008417 fucosyltransferase activity(GO:0008417)
2.0 30.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
2.0 8.1 GO:0045569 TRAIL binding(GO:0045569)
2.0 4.0 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
2.0 2.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
2.0 3.9 GO:0004660 protein farnesyltransferase activity(GO:0004660)
2.0 7.8 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
2.0 3.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.9 5.8 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.9 15.6 GO:1990405 protein antigen binding(GO:1990405)
1.9 673.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
1.9 17.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
1.9 3.8 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.9 5.7 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
1.9 33.9 GO:0008146 sulfotransferase activity(GO:0008146)
1.9 9.3 GO:0008373 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) sialyltransferase activity(GO:0008373)
1.9 7.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
1.9 242.5 GO:0017137 Rab GTPase binding(GO:0017137)
1.8 5.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.8 5.5 GO:0005042 netrin receptor activity(GO:0005042)
1.8 1.8 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
1.8 5.5 GO:0005055 laminin receptor activity(GO:0005055)
1.8 1.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
1.8 7.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.8 27.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
1.8 28.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
1.8 17.9 GO:0004707 MAP kinase activity(GO:0004707)
1.8 336.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
1.8 24.8 GO:1990459 transferrin receptor binding(GO:1990459)
1.8 28.2 GO:0008327 methyl-CpG binding(GO:0008327)
1.7 10.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
1.7 10.3 GO:0009378 four-way junction helicase activity(GO:0009378)
1.7 5.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
1.6 18.1 GO:0042577 lipid phosphatase activity(GO:0042577)
1.6 19.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
1.6 1.6 GO:0001855 complement component C4b binding(GO:0001855)
1.6 19.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
1.6 1.6 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
1.6 3.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.6 3.2 GO:0004040 amidase activity(GO:0004040)
1.6 4.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.6 7.9 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
1.6 17.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.5 23.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.5 6.2 GO:0016972 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
1.5 23.1 GO:0005158 insulin receptor binding(GO:0005158)
1.5 3.1 GO:0070052 collagen V binding(GO:0070052)
1.5 9.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.5 3.0 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
1.5 12.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.5 3.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.5 40.3 GO:0005044 scavenger receptor activity(GO:0005044)
1.5 5.9 GO:0005499 vitamin D binding(GO:0005499)
1.4 4.3 GO:0042289 MHC class II protein binding(GO:0042289)
1.4 4.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
1.4 7.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
1.4 4.3 GO:0004336 galactosylceramidase activity(GO:0004336)
1.4 4.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.4 39.8 GO:0008374 O-acyltransferase activity(GO:0008374)
1.4 149.3 GO:0005516 calmodulin binding(GO:0005516)
1.4 8.4 GO:0031419 cobalamin binding(GO:0031419)
1.4 4.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.4 31.4 GO:0001784 phosphotyrosine binding(GO:0001784)
1.4 5.4 GO:0042015 interleukin-20 binding(GO:0042015)
1.3 8.1 GO:0008430 selenium binding(GO:0008430)
1.3 17.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
1.3 5.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.3 13.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
1.3 18.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
1.3 7.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.3 32.6 GO:0070566 adenylyltransferase activity(GO:0070566)
1.3 3.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
1.3 15.4 GO:0042809 vitamin D receptor binding(GO:0042809)
1.3 3.8 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
1.3 23.0 GO:0000030 mannosyltransferase activity(GO:0000030)
1.2 3.7 GO:0015116 sulfate transmembrane transporter activity(GO:0015116)
1.2 4.9 GO:0030492 hemoglobin binding(GO:0030492)
1.2 7.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.2 6.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
1.2 1.2 GO:0015295 solute:proton symporter activity(GO:0015295)
1.2 15.4 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
1.2 70.9 GO:0004497 monooxygenase activity(GO:0004497)
1.2 4.7 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.2 17.5 GO:0051184 cofactor transporter activity(GO:0051184)
1.2 5.8 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
1.2 10.4 GO:0016805 dipeptidase activity(GO:0016805)
1.1 20.7 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
1.1 71.6 GO:0035064 methylated histone binding(GO:0035064)
1.1 5.6 GO:0003796 lysozyme activity(GO:0003796)
1.1 30.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
1.1 2.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
1.1 14.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
1.1 2.1 GO:0042008 interleukin-18 receptor activity(GO:0042008)
1.0 6.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
1.0 231.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.0 22.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
1.0 16.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
1.0 5.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
1.0 2.0 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
1.0 3.0 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
1.0 2.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
1.0 17.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.0 84.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
1.0 7.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
1.0 1.0 GO:0042806 fucose binding(GO:0042806)
0.9 8.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.9 0.9 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.9 37.8 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.9 63.4 GO:0005179 hormone activity(GO:0005179)
0.9 14.4 GO:0042056 chemoattractant activity(GO:0042056)
0.9 34.1 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.9 1.7 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.9 2.6 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.8 5.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.8 10.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.8 24.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.8 1.7 GO:0022834 ligand-gated ion channel activity(GO:0015276) ligand-gated channel activity(GO:0022834)
0.8 43.3 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.8 4.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.8 3.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.8 31.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.8 5.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.7 2.2 GO:0030274 LIM domain binding(GO:0030274)
0.7 9.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.7 3.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.7 1.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.7 5.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.7 6.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.7 46.6 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.7 10.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.7 825.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.7 0.7 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.7 4.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.7 2.0 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.7 8.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.6 2.6 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.6 1.8 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.6 1.8 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.6 2.3 GO:0000182 rDNA binding(GO:0000182)
0.6 14.9 GO:0000149 SNARE binding(GO:0000149)
0.6 1.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.6 2.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.6 2.8 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.5 14.8 GO:0008009 chemokine activity(GO:0008009)
0.5 3.2 GO:0043422 protein kinase B binding(GO:0043422)
0.5 15.3 GO:0042805 actinin binding(GO:0042805)
0.5 6.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.5 3.8 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.5 1.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.5 0.9 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.4 2.2 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.4 2.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.4 5.1 GO:0017022 myosin binding(GO:0017022)
0.4 1.7 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.4 4.2 GO:0005254 chloride channel activity(GO:0005254)
0.4 5.0 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 1.6 GO:0032452 histone demethylase activity(GO:0032452)
0.4 16.2 GO:0032947 protein complex scaffold(GO:0032947)
0.4 0.8 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.4 189.4 GO:0005509 calcium ion binding(GO:0005509)
0.4 1.1 GO:0008903 hydroxypyruvate isomerase activity(GO:0008903)
0.3 6.6 GO:0019838 growth factor binding(GO:0019838)
0.3 0.3 GO:0003909 DNA ligase activity(GO:0003909)
0.3 11.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.3 1.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 0.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 0.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.3 0.3 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.3 0.8 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.3 3.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.3 6.1 GO:0042169 SH2 domain binding(GO:0042169)
0.2 1.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.6 GO:0015079 potassium ion transmembrane transporter activity(GO:0015079)
0.2 1.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.2 12.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 4.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 0.8 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.4 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.1 1.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.5 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 21.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.5 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.0 GO:0036122 BMP binding(GO:0036122)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
51.5 51.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
18.1 762.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
15.2 15.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
14.1 169.5 ST GAQ PATHWAY G alpha q Pathway
9.9 238.0 PID LPA4 PATHWAY LPA4-mediated signaling events
8.7 243.8 PID S1P S1P4 PATHWAY S1P4 pathway
8.6 456.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
8.4 41.8 PID EPHB FWD PATHWAY EPHB forward signaling
8.1 32.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
7.7 176.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
7.5 14.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
7.3 80.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
6.7 414.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
6.3 6.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
6.1 85.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
6.0 555.0 PID FGF PATHWAY FGF signaling pathway
5.9 283.7 NABA COLLAGENS Genes encoding collagen proteins
5.8 192.1 PID RAS PATHWAY Regulation of Ras family activation
5.7 17.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
5.5 328.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
5.3 31.8 PID NECTIN PATHWAY Nectin adhesion pathway
5.3 10.5 PID S1P S1P2 PATHWAY S1P2 pathway
5.1 30.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
5.1 25.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
4.9 252.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
4.7 9.4 ST STAT3 PATHWAY STAT3 Pathway
4.7 46.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
4.6 96.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
4.6 123.1 PID WNT SIGNALING PATHWAY Wnt signaling network
4.5 163.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
4.4 83.8 PID S1P S1P3 PATHWAY S1P3 pathway
4.4 26.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
4.3 68.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
4.3 362.4 PID RHOA REG PATHWAY Regulation of RhoA activity
4.2 74.8 PID ALK2 PATHWAY ALK2 signaling events
4.2 161.9 PID REELIN PATHWAY Reelin signaling pathway
4.1 111.5 PID NETRIN PATHWAY Netrin-mediated signaling events
4.1 181.4 PID ARF6 PATHWAY Arf6 signaling events
4.1 36.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
4.0 286.1 PID HNF3A PATHWAY FOXA1 transcription factor network
4.0 187.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
3.9 74.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
3.8 26.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
3.8 94.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
3.7 210.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
3.7 51.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
3.7 749.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
3.6 83.5 ST GA13 PATHWAY G alpha 13 Pathway
3.6 10.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
3.6 14.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
3.4 58.5 PID GLYPICAN 1PATHWAY Glypican 1 network
3.3 73.5 PID EPHA FWDPATHWAY EPHA forward signaling
3.3 26.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
3.3 32.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
3.2 63.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
3.1 24.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
2.9 94.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
2.9 99.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
2.9 84.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
2.8 51.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
2.8 64.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
2.8 2.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
2.7 30.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
2.7 54.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
2.7 26.8 ST G ALPHA S PATHWAY G alpha s Pathway
2.6 56.7 PID IL1 PATHWAY IL1-mediated signaling events
2.5 52.7 ST G ALPHA I PATHWAY G alpha i Pathway
2.5 57.1 PID INSULIN PATHWAY Insulin Pathway
2.4 105.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
2.4 4.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
2.3 740.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
2.3 11.3 PID IL23 PATHWAY IL23-mediated signaling events
2.2 218.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
2.1 32.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
2.1 55.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
2.1 78.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
2.1 21.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
2.1 16.5 PID NOTCH PATHWAY Notch signaling pathway
2.1 82.1 PID LKB1 PATHWAY LKB1 signaling events
2.0 16.4 PID CONE PATHWAY Visual signal transduction: Cones
2.0 6.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
2.0 30.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
1.9 22.4 ST GA12 PATHWAY G alpha 12 Pathway
1.9 38.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
1.8 72.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.8 39.6 PID ENDOTHELIN PATHWAY Endothelins
1.8 32.0 SIG CHEMOTAXIS Genes related to chemotaxis
1.7 6.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.7 32.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
1.6 262.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.5 49.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
1.4 380.6 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
1.4 16.5 PID PI3KCI PATHWAY Class I PI3K signaling events
1.3 75.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
1.1 14.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
1.1 22.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.9 0.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.9 44.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.9 12.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.9 19.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.8 1.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.8 19.4 PID SHP2 PATHWAY SHP2 signaling
0.8 9.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.7 17.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.7 7.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.6 9.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.5 17.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.5 4.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.4 5.6 PID ALK1 PATHWAY ALK1 signaling events
0.3 5.3 PID RHOA PATHWAY RhoA signaling pathway
0.3 1.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
25.2 580.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
21.0 21.0 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
21.0 21.0 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
20.2 647.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
17.7 17.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
16.6 16.6 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
16.1 450.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
15.8 205.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
15.4 662.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
14.6 292.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
13.9 751.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
13.8 41.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
13.2 171.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
12.6 517.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
11.8 11.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
11.6 81.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
11.4 113.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
11.3 78.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
10.8 21.7 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
10.0 230.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
9.7 58.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
9.7 115.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
9.0 144.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
9.0 125.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
8.5 127.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
8.3 133.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
8.3 314.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
8.1 217.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
8.0 289.8 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
7.9 198.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
7.8 62.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
7.7 115.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
7.7 562.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
7.6 237.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
7.6 38.1 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
7.6 317.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
7.4 162.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
7.1 135.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
7.0 112.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
6.8 135.0 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
6.7 160.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
6.5 149.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
6.4 108.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
6.4 127.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
6.3 341.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
6.3 62.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
6.1 60.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
6.0 277.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
6.0 6.0 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
5.8 5.8 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
5.6 73.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
5.6 124.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
5.5 165.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
5.3 170.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
5.3 216.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
5.3 110.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
5.2 123.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
5.0 75.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
5.0 64.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
4.9 29.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
4.8 129.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
4.8 536.3 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
4.7 9.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
4.6 564.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
4.5 4.5 REACTOME PHOSPHOLIPASE C MEDIATED CASCADE Genes involved in Phospholipase C-mediated cascade
4.5 77.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
4.5 9.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
4.3 94.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
4.3 77.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
4.3 4.3 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
4.2 501.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
4.2 691.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
4.1 65.1 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
3.9 98.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
3.9 85.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
3.9 3.9 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
3.9 7.7 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
3.8 133.2 REACTOME AMYLOIDS Genes involved in Amyloids
3.7 67.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
3.7 40.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
3.6 115.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
3.5 63.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
3.5 56.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
3.5 126.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
3.4 152.9 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
3.4 144.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
3.3 59.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
3.3 145.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
3.3 32.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
3.2 126.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
3.2 57.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
3.2 22.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
3.1 52.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
3.0 24.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
2.9 235.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
2.8 5.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
2.8 11.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
2.8 102.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
2.8 30.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
2.7 19.2 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
2.7 62.9 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
2.7 270.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
2.7 2.7 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
2.6 154.6 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
2.6 46.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
2.5 22.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
2.5 10.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
2.5 5.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
2.5 22.4 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
2.4 29.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
2.4 33.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
2.4 55.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
2.4 36.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
2.4 16.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
2.3 18.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
2.2 17.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
2.2 4.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
2.0 32.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
1.8 34.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
1.7 38.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
1.7 132.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
1.6 18.9 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
1.6 31.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
1.5 4.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
1.5 9.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
1.5 31.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.4 11.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
1.4 4.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
1.4 21.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.3 7.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.3 6.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
1.3 3.8 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
1.3 10.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.2 3.5 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
1.1 21.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.1 14.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
1.1 14.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
1.0 26.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
1.0 17.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
1.0 10.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
1.0 6.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.0 6.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.9 17.8 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.9 12.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.9 9.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.8 17.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.8 2.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.8 250.2 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.8 15.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.7 2.2 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.7 19.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.7 3.3 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.6 12.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.6 14.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.5 10.3 REACTOME PI 3K CASCADE Genes involved in PI-3K cascade
0.5 6.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.5 8.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.5 8.0 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.5 18.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 7.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.4 45.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.4 2.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 9.4 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.3 4.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 22.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.3 5.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 7.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 3.3 REACTOME DEFENSINS Genes involved in Defensins
0.2 5.3 REACTOME KINESINS Genes involved in Kinesins
0.1 4.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 0.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling