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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
Z-value: 7.85
Motif logo
Transcription factors associated with YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
YBX1
|
ENSG00000065978.19 | YBX1 |
|
FOS
|
ENSG00000170345.10 | FOS |
|
NFYC
|
ENSG00000066136.20 | NFYC |
|
NFYA
|
ENSG00000001167.15 | NFYA |
|
NFYB
|
ENSG00000120837.8 | NFYB |
|
CEBPZ
|
ENSG00000115816.15 | CEBPZ |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CEBPZ | hg38_v1_chr2_-_37231549_37231603 | 0.85 | 4.0e-62 | Click! |
| YBX1 | hg38_v1_chr1_+_42682954_42683039 | 0.79 | 1.9e-47 | Click! |
| NFYC | hg38_v1_chr1_+_40738834_40738874 | 0.68 | 1.2e-30 | Click! |
| NFYB | hg38_v1_chr12_-_104138007_104138035 | 0.48 | 9.1e-14 | Click! |
| FOS | hg38_v1_chr14_+_75279637_75279670 | -0.40 | 9.1e-10 | Click! |
| NFYA | hg38_v1_chr6_+_41072939_41072984 | -0.03 | 7.1e-01 | Click! |
Activity profile of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif
Sorted Z-values of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ motif
Network of associatons between targets according to the STRING database.
First level regulatory network of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 180.5 | 541.5 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 110.2 | 330.5 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
| 87.5 | 262.4 | GO:0060623 | regulation of chromosome condensation(GO:0060623) |
| 82.5 | 742.4 | GO:0010994 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 73.9 | 960.8 | GO:0006265 | DNA topological change(GO:0006265) |
| 65.6 | 721.5 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 63.3 | 316.7 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 62.8 | 188.4 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
| 61.0 | 365.9 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 60.8 | 182.5 | GO:0072387 | flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006) |
| 60.7 | 182.1 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) |
| 54.6 | 218.3 | GO:0006272 | leading strand elongation(GO:0006272) |
| 52.7 | 474.5 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 52.6 | 315.8 | GO:0016321 | female meiosis chromosome segregation(GO:0016321) |
| 50.2 | 401.8 | GO:0016129 | phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129) |
| 44.3 | 132.8 | GO:0090155 | negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) |
| 41.3 | 206.3 | GO:0033384 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 40.9 | 409.0 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 39.8 | 318.2 | GO:0014038 | regulation of Schwann cell differentiation(GO:0014038) |
| 39.1 | 117.4 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 37.3 | 111.8 | GO:0010520 | meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520) |
| 37.0 | 259.3 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 36.4 | 472.7 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 35.8 | 679.7 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 35.5 | 142.1 | GO:1904045 | cellular response to aldosterone(GO:1904045) |
| 34.9 | 139.6 | GO:0090579 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 34.7 | 104.1 | GO:0034241 | macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) |
| 34.1 | 136.3 | GO:0033489 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 31.6 | 220.9 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 30.5 | 30.5 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 28.9 | 86.8 | GO:0072334 | UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334) |
| 28.6 | 85.9 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
| 28.0 | 168.2 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 27.0 | 54.0 | GO:0000912 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 26.9 | 80.8 | GO:2000374 | regulation of oxygen metabolic process(GO:2000374) |
| 26.0 | 155.8 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 25.0 | 25.0 | GO:1903181 | regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) |
| 23.4 | 116.8 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 23.4 | 93.4 | GO:0009216 | adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) |
| 23.1 | 69.4 | GO:0071373 | cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373) |
| 22.8 | 273.4 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 22.4 | 44.9 | GO:0005997 | xylulose metabolic process(GO:0005997) |
| 22.2 | 66.7 | GO:0008614 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) |
| 22.2 | 932.1 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 21.9 | 175.2 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 21.8 | 87.1 | GO:0009138 | pyrimidine nucleoside diphosphate metabolic process(GO:0009138) |
| 21.6 | 129.5 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 21.3 | 256.0 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 20.7 | 62.2 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 19.8 | 277.4 | GO:1903297 | regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) |
| 19.7 | 314.7 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 19.6 | 255.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 19.3 | 96.6 | GO:0019322 | pentose biosynthetic process(GO:0019322) |
| 19.2 | 57.7 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 18.8 | 94.0 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 18.8 | 56.4 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
| 18.7 | 74.6 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 18.2 | 54.6 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 18.1 | 289.7 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 18.0 | 54.0 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 18.0 | 378.0 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 17.8 | 35.7 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 17.6 | 899.2 | GO:0043486 | histone exchange(GO:0043486) |
| 17.4 | 191.7 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 17.2 | 51.5 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 17.0 | 51.1 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 17.0 | 50.9 | GO:1903925 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 16.6 | 49.8 | GO:0015746 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 16.6 | 99.3 | GO:2000781 | positive regulation of double-strand break repair(GO:2000781) |
| 16.4 | 32.8 | GO:0002840 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) |
| 16.3 | 163.5 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 16.2 | 178.3 | GO:0010965 | regulation of mitotic sister chromatid separation(GO:0010965) |
| 16.1 | 80.6 | GO:0061738 | late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 15.9 | 63.5 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 15.6 | 31.2 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 15.5 | 77.4 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 15.4 | 30.8 | GO:0009136 | ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188) |
| 15.2 | 91.1 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 15.1 | 166.2 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 15.1 | 377.0 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 14.9 | 431.2 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 14.7 | 265.3 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 14.7 | 44.2 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 14.7 | 29.5 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 14.7 | 58.9 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 14.6 | 423.9 | GO:0007094 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 14.6 | 947.9 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 14.5 | 58.1 | GO:2000259 | positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 14.5 | 14.5 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 14.3 | 172.0 | GO:0042407 | cristae formation(GO:0042407) |
| 14.3 | 71.4 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 14.3 | 114.1 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 14.2 | 185.2 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 14.1 | 268.7 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 13.8 | 110.4 | GO:0055129 | proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129) |
| 13.8 | 41.4 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 13.8 | 68.9 | GO:1904925 | positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 13.6 | 54.6 | GO:0035750 | protein localization to myelin sheath abaxonal region(GO:0035750) |
| 13.6 | 54.6 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 13.6 | 136.2 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 13.5 | 27.1 | GO:0010621 | negative regulation of transcription by transcription factor localization(GO:0010621) |
| 13.5 | 67.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 13.4 | 26.9 | GO:0009149 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) |
| 13.4 | 187.2 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 13.1 | 92.0 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 13.1 | 39.3 | GO:1904245 | regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 13.1 | 52.2 | GO:0035910 | ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 12.8 | 38.3 | GO:0097501 | stress response to metal ion(GO:0097501) |
| 12.4 | 160.9 | GO:0045008 | depyrimidination(GO:0045008) |
| 12.4 | 12.4 | GO:0035822 | gene conversion(GO:0035822) |
| 12.2 | 183.2 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 12.2 | 36.6 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 12.1 | 84.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 11.9 | 237.8 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 11.7 | 93.4 | GO:0046104 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 11.7 | 186.6 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 11.5 | 91.7 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 11.4 | 11.4 | GO:1903438 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 11.3 | 541.5 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 11.2 | 100.7 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 11.1 | 33.3 | GO:0051305 | chromosome movement towards spindle pole(GO:0051305) |
| 11.1 | 310.4 | GO:0019054 | modulation by virus of host process(GO:0019054) |
| 11.0 | 547.7 | GO:0007077 | mitotic nuclear envelope disassembly(GO:0007077) |
| 10.9 | 54.5 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 10.8 | 43.2 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 10.7 | 32.1 | GO:0070510 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
| 10.7 | 32.1 | GO:1901355 | response to rapamycin(GO:1901355) |
| 10.7 | 96.1 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 10.7 | 277.5 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 10.7 | 32.0 | GO:2000697 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697) |
| 10.5 | 31.6 | GO:0009106 | lipoate metabolic process(GO:0009106) |
| 10.5 | 62.7 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 10.4 | 405.6 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 10.4 | 10.4 | GO:0072282 | metanephric nephron tubule morphogenesis(GO:0072282) |
| 10.3 | 30.9 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 10.3 | 71.9 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 10.2 | 194.0 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 10.1 | 50.3 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 9.9 | 29.6 | GO:0072019 | proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) metanephric proximal tubule development(GO:0072237) |
| 9.8 | 29.4 | GO:0071680 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) |
| 9.7 | 38.7 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
| 9.6 | 220.0 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 9.5 | 286.3 | GO:0072663 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 9.5 | 28.5 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) histone H3-K4 acetylation(GO:0043973) |
| 9.3 | 37.4 | GO:1901873 | regulation of post-translational protein modification(GO:1901873) |
| 9.1 | 36.5 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 9.1 | 135.8 | GO:0000338 | protein deneddylation(GO:0000338) |
| 9.0 | 63.1 | GO:0009249 | protein lipoylation(GO:0009249) |
| 9.0 | 143.4 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 9.0 | 125.3 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 8.8 | 35.0 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 8.7 | 17.4 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 8.7 | 26.0 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 8.5 | 17.0 | GO:0061009 | common bile duct development(GO:0061009) |
| 8.5 | 101.6 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 8.5 | 50.7 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 8.2 | 24.7 | GO:0070828 | heterochromatin organization(GO:0070828) |
| 8.2 | 24.6 | GO:0045643 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 8.2 | 24.5 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 8.1 | 89.3 | GO:0070200 | establishment of protein localization to telomere(GO:0070200) |
| 8.1 | 32.4 | GO:0046116 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 8.0 | 644.3 | GO:0006695 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
| 7.9 | 230.1 | GO:0006465 | signal peptide processing(GO:0006465) |
| 7.8 | 15.7 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
| 7.8 | 46.5 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 7.7 | 77.4 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 7.6 | 121.6 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 7.6 | 7.6 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 7.5 | 37.7 | GO:0034398 | telomere tethering at nuclear periphery(GO:0034398) |
| 7.5 | 45.2 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 7.5 | 22.5 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
| 7.5 | 239.7 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 7.5 | 52.2 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 7.5 | 119.4 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 7.4 | 29.5 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 7.3 | 51.3 | GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 7.3 | 51.2 | GO:0090343 | positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774) |
| 7.3 | 277.4 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 7.3 | 21.8 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
| 7.2 | 28.7 | GO:0015853 | adenine transport(GO:0015853) |
| 7.1 | 14.2 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 7.0 | 48.8 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 6.9 | 27.7 | GO:0030423 | targeting of mRNA for destruction involved in RNA interference(GO:0030423) |
| 6.8 | 40.8 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 6.7 | 33.7 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 6.7 | 26.9 | GO:0030047 | actin modification(GO:0030047) |
| 6.7 | 67.1 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 6.7 | 80.1 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 6.6 | 46.4 | GO:0033262 | regulation of nuclear cell cycle DNA replication(GO:0033262) |
| 6.6 | 33.1 | GO:0045005 | DNA-dependent DNA replication maintenance of fidelity(GO:0045005) |
| 6.6 | 33.1 | GO:0003415 | chondrocyte hypertrophy(GO:0003415) |
| 6.6 | 19.7 | GO:0042369 | vitamin D catabolic process(GO:0042369) |
| 6.5 | 19.6 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 6.5 | 58.3 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 6.4 | 25.7 | GO:0002188 | translation reinitiation(GO:0002188) |
| 6.4 | 51.3 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 6.4 | 19.2 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 6.4 | 89.7 | GO:0098877 | neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540) |
| 6.4 | 51.2 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 6.4 | 31.8 | GO:0010193 | response to ozone(GO:0010193) |
| 6.4 | 50.8 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 6.3 | 44.4 | GO:1902969 | mitotic DNA replication(GO:1902969) |
| 6.3 | 114.0 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
| 6.3 | 18.9 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
| 6.3 | 6.3 | GO:2000850 | negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 6.3 | 143.8 | GO:0051639 | actin filament network formation(GO:0051639) |
| 6.2 | 18.6 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
| 6.1 | 6.1 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 6.1 | 12.1 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
| 6.1 | 12.1 | GO:0046504 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 6.0 | 53.7 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 5.9 | 82.0 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 5.8 | 174.2 | GO:0006301 | postreplication repair(GO:0006301) |
| 5.8 | 75.2 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 5.8 | 51.9 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 5.7 | 11.4 | GO:0051795 | positive regulation of catagen(GO:0051795) |
| 5.7 | 11.4 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
| 5.6 | 78.7 | GO:0043248 | proteasome assembly(GO:0043248) |
| 5.6 | 28.1 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 5.6 | 83.3 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 5.5 | 38.6 | GO:0033183 | negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 5.5 | 54.9 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 5.5 | 21.9 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 5.5 | 169.4 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 5.4 | 37.9 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 5.3 | 26.7 | GO:0002880 | chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) |
| 5.3 | 47.5 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 5.2 | 109.5 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
| 5.2 | 10.3 | GO:0071033 | nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 5.2 | 15.5 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
| 5.1 | 25.6 | GO:0080009 | mRNA methylation(GO:0080009) |
| 5.0 | 206.2 | GO:0050832 | defense response to fungus(GO:0050832) |
| 5.0 | 20.1 | GO:0018201 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) |
| 5.0 | 15.0 | GO:1904872 | regulation of telomerase RNA localization to Cajal body(GO:1904872) |
| 5.0 | 39.9 | GO:1905216 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
| 5.0 | 153.7 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 4.9 | 29.6 | GO:2000373 | regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 4.9 | 283.1 | GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) |
| 4.9 | 24.3 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 4.9 | 34.0 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 4.8 | 14.5 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 4.8 | 71.3 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 4.7 | 14.2 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 4.7 | 14.2 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 4.7 | 14.2 | GO:1901253 | regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253) |
| 4.7 | 33.1 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 4.6 | 59.8 | GO:0002192 | IRES-dependent translational initiation(GO:0002192) |
| 4.6 | 384.7 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 4.6 | 50.1 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 4.5 | 40.9 | GO:0030497 | fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 4.5 | 18.2 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 4.5 | 330.1 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 4.5 | 45.2 | GO:0006108 | malate metabolic process(GO:0006108) |
| 4.5 | 94.1 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 4.5 | 13.4 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 4.4 | 13.3 | GO:0031441 | negative regulation of mRNA 3'-end processing(GO:0031441) |
| 4.4 | 17.5 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 4.4 | 8.7 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 4.3 | 12.9 | GO:0036466 | synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149) |
| 4.3 | 12.9 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 4.3 | 21.4 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 4.2 | 8.4 | GO:0002331 | pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331) |
| 4.2 | 12.6 | GO:0060266 | negative regulation of respiratory burst involved in inflammatory response(GO:0060266) |
| 4.2 | 8.3 | GO:0048199 | vesicle targeting, to, from or within Golgi(GO:0048199) |
| 4.1 | 28.9 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
| 4.1 | 16.5 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 4.1 | 8.2 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 4.0 | 72.9 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224) |
| 4.0 | 76.2 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 4.0 | 12.0 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
| 4.0 | 8.0 | GO:1903626 | positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626) |
| 3.9 | 43.0 | GO:0051983 | regulation of chromosome segregation(GO:0051983) |
| 3.9 | 27.2 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 3.9 | 7.8 | GO:1904378 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 3.9 | 31.0 | GO:0031087 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 3.9 | 7.7 | GO:0051794 | catagen(GO:0042637) regulation of catagen(GO:0051794) |
| 3.8 | 15.3 | GO:0051299 | mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299) |
| 3.8 | 71.7 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 3.8 | 15.0 | GO:1990834 | response to odorant(GO:1990834) |
| 3.7 | 22.4 | GO:0042695 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
| 3.7 | 22.2 | GO:0072718 | response to cisplatin(GO:0072718) |
| 3.7 | 18.3 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 3.6 | 7.2 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 3.6 | 10.8 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 3.5 | 10.6 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 3.5 | 264.7 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 3.5 | 28.2 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 3.4 | 10.3 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 3.4 | 48.1 | GO:0036109 | alpha-linolenic acid metabolic process(GO:0036109) |
| 3.4 | 230.2 | GO:0042267 | natural killer cell mediated cytotoxicity(GO:0042267) |
| 3.4 | 10.3 | GO:1904526 | regulation of microtubule binding(GO:1904526) |
| 3.4 | 50.9 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 3.4 | 20.3 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 3.3 | 9.9 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 3.3 | 9.9 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 3.3 | 13.2 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 3.2 | 175.5 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 3.2 | 129.7 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 3.2 | 207.1 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 3.2 | 51.4 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 3.2 | 19.0 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 3.2 | 15.8 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
| 3.1 | 22.0 | GO:0034982 | mitochondrial protein processing(GO:0034982) |
| 3.1 | 6.2 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 3.1 | 9.2 | GO:0031550 | positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550) |
| 3.1 | 30.6 | GO:0051451 | myoblast migration(GO:0051451) |
| 3.0 | 6.1 | GO:0032364 | oxygen homeostasis(GO:0032364) |
| 3.0 | 6.1 | GO:0040031 | snRNA modification(GO:0040031) |
| 3.0 | 15.1 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 3.0 | 18.0 | GO:0032392 | DNA geometric change(GO:0032392) |
| 3.0 | 11.9 | GO:0051026 | chiasma assembly(GO:0051026) |
| 3.0 | 8.9 | GO:0090427 | embryonic nail plate morphogenesis(GO:0035880) activation of meiosis(GO:0090427) |
| 3.0 | 17.8 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 3.0 | 8.9 | GO:0048254 | snoRNA localization(GO:0048254) |
| 2.9 | 46.2 | GO:0000478 | endonucleolytic cleavage involved in rRNA processing(GO:0000478) |
| 2.9 | 14.4 | GO:0015862 | uridine transport(GO:0015862) |
| 2.9 | 8.6 | GO:0052572 | response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) |
| 2.8 | 8.4 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 2.8 | 5.6 | GO:1902513 | regulation of organelle transport along microtubule(GO:1902513) |
| 2.8 | 14.0 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) prostate gland growth(GO:0060736) |
| 2.8 | 11.1 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 2.7 | 54.7 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 2.7 | 10.8 | GO:0030862 | positive regulation of polarized epithelial cell differentiation(GO:0030862) |
| 2.7 | 101.5 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 2.6 | 31.8 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 2.6 | 20.9 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
| 2.6 | 15.7 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 2.6 | 18.2 | GO:0014870 | response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 2.6 | 7.8 | GO:0001927 | exocyst assembly(GO:0001927) |
| 2.5 | 10.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 2.5 | 10.1 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 2.5 | 12.6 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 2.5 | 7.4 | GO:0042938 | dipeptide transport(GO:0042938) |
| 2.4 | 29.0 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 2.4 | 21.7 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 2.4 | 48.2 | GO:0071451 | removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) |
| 2.4 | 7.2 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 2.4 | 19.3 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 2.4 | 12.0 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 2.4 | 38.3 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 2.4 | 7.1 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 2.4 | 68.8 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 2.4 | 82.4 | GO:0045739 | positive regulation of DNA repair(GO:0045739) |
| 2.3 | 7.0 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 2.3 | 14.0 | GO:1905146 | lysosomal protein catabolic process(GO:1905146) |
| 2.3 | 30.2 | GO:1903286 | regulation of potassium ion import(GO:1903286) |
| 2.3 | 29.9 | GO:0009452 | 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 2.3 | 6.8 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 2.2 | 22.5 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 2.2 | 8.9 | GO:0036229 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 2.2 | 15.6 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 2.2 | 6.7 | GO:1904502 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
| 2.2 | 28.7 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 2.2 | 153.7 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 2.2 | 10.9 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 2.2 | 47.5 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 2.2 | 8.6 | GO:0007144 | female meiosis I(GO:0007144) |
| 2.1 | 83.5 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 2.1 | 8.4 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
| 2.1 | 29.1 | GO:0009629 | response to gravity(GO:0009629) |
| 2.1 | 14.5 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 2.1 | 4.1 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 2.1 | 4.1 | GO:0045410 | positive regulation of interleukin-6 biosynthetic process(GO:0045410) |
| 2.1 | 6.2 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 2.0 | 12.2 | GO:2001206 | positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206) |
| 2.0 | 16.2 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 2.0 | 4.0 | GO:0036446 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) negative regulation of vascular smooth muscle cell differentiation(GO:1905064) |
| 2.0 | 19.5 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 2.0 | 39.0 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 1.9 | 15.4 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 1.9 | 28.9 | GO:0045116 | protein neddylation(GO:0045116) |
| 1.9 | 26.7 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
| 1.9 | 58.1 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 1.9 | 13.1 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 1.8 | 9.2 | GO:0097278 | complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) |
| 1.8 | 3.7 | GO:0003064 | regulation of heart rate by hormone(GO:0003064) |
| 1.8 | 3.6 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) |
| 1.8 | 10.7 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 1.8 | 47.3 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 1.8 | 92.9 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 1.7 | 5.2 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 1.7 | 8.7 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 1.7 | 6.8 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 1.7 | 15.4 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 1.7 | 79.8 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 1.7 | 5.1 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 1.7 | 18.5 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 1.6 | 8.2 | GO:0060022 | hard palate development(GO:0060022) |
| 1.6 | 4.9 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 1.6 | 58.5 | GO:0043388 | positive regulation of DNA binding(GO:0043388) |
| 1.6 | 6.4 | GO:0051697 | protein delipidation(GO:0051697) |
| 1.6 | 4.8 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
| 1.6 | 3.2 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 1.6 | 82.8 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 1.6 | 34.5 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 1.5 | 27.9 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 1.5 | 6.2 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
| 1.5 | 47.2 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 1.5 | 16.6 | GO:0006787 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 1.5 | 3.0 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 1.5 | 4.4 | GO:1903826 | arginine transmembrane transport(GO:1903826) |
| 1.5 | 14.7 | GO:2000394 | positive regulation of lamellipodium morphogenesis(GO:2000394) |
| 1.5 | 16.1 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 1.5 | 16.1 | GO:0017085 | response to insecticide(GO:0017085) |
| 1.4 | 50.0 | GO:0042438 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
| 1.4 | 25.3 | GO:0031639 | plasminogen activation(GO:0031639) |
| 1.4 | 270.1 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 1.4 | 26.3 | GO:0030488 | tRNA methylation(GO:0030488) |
| 1.4 | 12.3 | GO:0002441 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 1.4 | 10.8 | GO:0051601 | exocyst localization(GO:0051601) |
| 1.3 | 13.4 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 1.3 | 11.8 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 1.3 | 11.6 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 1.3 | 7.7 | GO:0008218 | bioluminescence(GO:0008218) |
| 1.3 | 14.1 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 1.3 | 3.8 | GO:0006868 | glutamine transport(GO:0006868) |
| 1.3 | 6.4 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 1.3 | 6.3 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 1.2 | 5.0 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 1.2 | 1.2 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
| 1.2 | 6.1 | GO:0021563 | glossopharyngeal nerve development(GO:0021563) |
| 1.2 | 5.9 | GO:0060017 | parathyroid gland development(GO:0060017) |
| 1.2 | 8.3 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 1.2 | 4.7 | GO:0071418 | cellular response to amine stimulus(GO:0071418) |
| 1.2 | 57.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 1.2 | 45.3 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 1.2 | 1.2 | GO:0032912 | negative regulation of transforming growth factor beta2 production(GO:0032912) |
| 1.1 | 25.1 | GO:0031648 | protein destabilization(GO:0031648) |
| 1.1 | 46.8 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 1.1 | 14.4 | GO:1903541 | regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543) exosomal secretion(GO:1990182) |
| 1.1 | 6.7 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 1.1 | 4.4 | GO:0070091 | glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092) |
| 1.1 | 3.3 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 1.1 | 27.3 | GO:0006506 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
| 1.1 | 11.9 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 1.1 | 44.9 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 1.1 | 189.1 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 1.1 | 14.9 | GO:0051014 | actin filament severing(GO:0051014) |
| 1.1 | 12.8 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 1.1 | 7.4 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
| 1.1 | 3.2 | GO:0044351 | macropinocytosis(GO:0044351) |
| 1.0 | 11.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 1.0 | 5.2 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 1.0 | 4.1 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 1.0 | 10.3 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 1.0 | 29.5 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 1.0 | 7.1 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 1.0 | 3.0 | GO:0001916 | positive regulation of T cell mediated cytotoxicity(GO:0001916) |
| 1.0 | 4.0 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 1.0 | 2.0 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 1.0 | 8.9 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 1.0 | 54.9 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 1.0 | 19.5 | GO:0051569 | regulation of histone H3-K4 methylation(GO:0051569) |
| 1.0 | 51.6 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 1.0 | 1.9 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.9 | 12.1 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.9 | 59.4 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.9 | 8.2 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.9 | 19.1 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.9 | 2.7 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.9 | 10.8 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.9 | 12.4 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.9 | 7.9 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.8 | 1.7 | GO:0043311 | positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
| 0.8 | 42.9 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.8 | 10.9 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.8 | 10.6 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.8 | 13.8 | GO:0009226 | nucleotide-sugar biosynthetic process(GO:0009226) |
| 0.8 | 3.2 | GO:2000696 | regulation of epithelial cell differentiation involved in kidney development(GO:2000696) |
| 0.8 | 3.2 | GO:0018197 | peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.8 | 2.4 | GO:2000417 | negative regulation of eosinophil migration(GO:2000417) |
| 0.8 | 0.8 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 0.7 | 5.2 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.7 | 36.6 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.7 | 3.6 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.7 | 89.0 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.7 | 6.4 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.7 | 4.3 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.7 | 7.1 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.7 | 5.6 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.7 | 2.1 | GO:0031455 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.7 | 12.3 | GO:0043981 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.7 | 45.0 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.7 | 8.1 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.7 | 2.7 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.7 | 17.8 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.7 | 9.9 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.7 | 2.0 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.7 | 6.6 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.7 | 10.4 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.7 | 1.3 | GO:0002906 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 0.6 | 3.2 | GO:0048845 | venous blood vessel morphogenesis(GO:0048845) |
| 0.6 | 1.9 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 0.6 | 5.1 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.6 | 6.4 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.6 | 6.9 | GO:0071276 | cellular response to cadmium ion(GO:0071276) |
| 0.6 | 2.5 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.6 | 6.8 | GO:2001288 | regulation of caveolin-mediated endocytosis(GO:2001286) positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.6 | 3.7 | GO:0051176 | positive regulation of sulfur metabolic process(GO:0051176) |
| 0.6 | 5.5 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.6 | 0.6 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.6 | 24.0 | GO:0045851 | pH reduction(GO:0045851) |
| 0.6 | 15.6 | GO:0014904 | myotube cell development(GO:0014904) |
| 0.6 | 28.8 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.6 | 16.0 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.6 | 3.4 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.6 | 10.8 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.6 | 8.9 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.6 | 1.7 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.5 | 9.8 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.5 | 72.5 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.5 | 0.5 | GO:0035977 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
| 0.5 | 10.5 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.5 | 4.9 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.5 | 4.4 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.5 | 3.4 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.5 | 7.3 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.5 | 0.9 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
| 0.4 | 12.0 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.4 | 1.7 | GO:2000015 | regulation of determination of dorsal identity(GO:2000015) |
| 0.4 | 2.9 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.4 | 4.4 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.4 | 4.8 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.4 | 3.9 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.4 | 2.7 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.4 | 5.4 | GO:0097502 | mannosylation(GO:0097502) |
| 0.4 | 0.8 | GO:1901876 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 0.4 | 5.3 | GO:0009169 | ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) |
| 0.4 | 2.5 | GO:2000809 | planar cell polarity pathway involved in axis elongation(GO:0003402) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.3 | 0.3 | GO:0032304 | negative regulation of icosanoid secretion(GO:0032304) |
| 0.3 | 1.0 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 0.3 | 0.6 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 0.3 | 16.9 | GO:0071357 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.3 | 3.0 | GO:0034383 | low-density lipoprotein particle clearance(GO:0034383) |
| 0.3 | 1.8 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.3 | 2.0 | GO:0030091 | protein repair(GO:0030091) |
| 0.3 | 2.3 | GO:0050872 | white fat cell differentiation(GO:0050872) |
| 0.3 | 0.8 | GO:0035963 | cellular response to interleukin-13(GO:0035963) |
| 0.3 | 5.7 | GO:0071806 | protein transmembrane transport(GO:0071806) |
| 0.3 | 30.1 | GO:0071466 | cellular response to xenobiotic stimulus(GO:0071466) |
| 0.3 | 1.9 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.3 | 0.8 | GO:0097112 | gamma-aminobutyric acid receptor clustering(GO:0097112) |
| 0.3 | 5.9 | GO:1901998 | toxin transport(GO:1901998) |
| 0.3 | 2.6 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.3 | 3.1 | GO:2000009 | negative regulation of protein localization to cell surface(GO:2000009) |
| 0.3 | 0.5 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.2 | 0.2 | GO:0003408 | optic cup formation involved in camera-type eye development(GO:0003408) |
| 0.2 | 10.8 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
| 0.2 | 7.6 | GO:0050999 | regulation of nitric-oxide synthase activity(GO:0050999) |
| 0.2 | 1.8 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.2 | 2.0 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.2 | 0.8 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.2 | 0.8 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482) |
| 0.2 | 1.3 | GO:0046449 | creatinine metabolic process(GO:0046449) |
| 0.2 | 5.6 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.2 | 0.9 | GO:0043485 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
| 0.2 | 1.4 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.2 | 0.9 | GO:0042473 | outer ear morphogenesis(GO:0042473) |
| 0.2 | 3.0 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.2 | 2.4 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.2 | 1.1 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.1 | 16.7 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.1 | 2.7 | GO:0051341 | regulation of oxidoreductase activity(GO:0051341) |
| 0.1 | 1.9 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
| 0.1 | 0.8 | GO:0001967 | suckling behavior(GO:0001967) |
| 0.1 | 15.4 | GO:0031424 | keratinization(GO:0031424) |
| 0.1 | 1.2 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.1 | 0.5 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.1 | 1.8 | GO:0030728 | ovulation(GO:0030728) |
| 0.1 | 0.6 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.1 | 0.7 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.1 | 0.5 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 0.4 | GO:0030238 | male sex determination(GO:0030238) |
| 0.1 | 1.6 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.1 | 0.3 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.0 | 0.2 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.0 | 0.1 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.0 | 0.7 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.0 | 0.6 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.4 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.0 | 0.1 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.0 | 0.1 | GO:0060346 | bone trabecula formation(GO:0060346) |
| 0.0 | 0.1 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.0 | 0.2 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.0 | 0.3 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 133.7 | 534.6 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 124.7 | 623.7 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 103.5 | 310.6 | GO:1990298 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 71.6 | 644.1 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 60.5 | 242.1 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 56.1 | 168.2 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 54.4 | 490.0 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 52.2 | 156.7 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 50.3 | 754.7 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 45.8 | 137.5 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 45.6 | 182.5 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 45.5 | 136.4 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 42.3 | 169.0 | GO:0005715 | late recombination nodule(GO:0005715) |
| 42.1 | 210.5 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 41.7 | 1208.3 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 41.6 | 664.9 | GO:0005642 | annulate lamellae(GO:0005642) |
| 41.5 | 165.8 | GO:0031211 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 36.7 | 146.8 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 31.3 | 94.0 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 30.2 | 393.0 | GO:0042555 | MCM complex(GO:0042555) |
| 29.9 | 567.4 | GO:0000812 | Swr1 complex(GO:0000812) |
| 29.7 | 148.5 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 29.1 | 348.9 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 26.8 | 429.1 | GO:0034709 | methylosome(GO:0034709) |
| 25.7 | 230.9 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 25.2 | 252.4 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 24.7 | 197.9 | GO:1905202 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 24.6 | 49.1 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 24.0 | 168.2 | GO:0016272 | prefoldin complex(GO:0016272) |
| 23.6 | 141.6 | GO:0061617 | MICOS complex(GO:0061617) |
| 23.4 | 187.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 23.2 | 208.8 | GO:0042382 | paraspeckles(GO:0042382) |
| 22.4 | 89.7 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 22.2 | 22.2 | GO:0035061 | interchromatin granule(GO:0035061) |
| 21.6 | 129.5 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 20.5 | 82.1 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 19.8 | 336.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 19.4 | 213.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 18.8 | 75.4 | GO:0070876 | SOSS complex(GO:0070876) |
| 18.5 | 111.0 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 18.0 | 71.8 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 17.6 | 969.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 17.6 | 105.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 17.3 | 69.2 | GO:0031261 | DNA replication preinitiation complex(GO:0031261) |
| 17.3 | 103.7 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 17.0 | 220.4 | GO:0005688 | U6 snRNP(GO:0005688) |
| 16.9 | 101.5 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 16.8 | 67.1 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 15.3 | 30.5 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 15.1 | 105.6 | GO:0072589 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 14.4 | 172.5 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 14.1 | 70.5 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 13.3 | 39.9 | GO:0034657 | GID complex(GO:0034657) |
| 13.1 | 339.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 12.9 | 103.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 12.9 | 64.4 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 12.8 | 63.8 | GO:0033503 | HULC complex(GO:0033503) |
| 12.7 | 50.7 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 12.6 | 50.3 | GO:0071942 | XPC complex(GO:0071942) |
| 12.5 | 24.9 | GO:1903349 | omegasome membrane(GO:1903349) |
| 12.2 | 36.5 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 11.8 | 59.1 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 11.8 | 58.9 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 11.7 | 152.4 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 11.5 | 45.9 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 11.5 | 137.6 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 11.4 | 68.4 | GO:0001940 | male pronucleus(GO:0001940) |
| 11.3 | 33.9 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 11.2 | 78.4 | GO:0000235 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 11.2 | 44.8 | GO:0071817 | MMXD complex(GO:0071817) |
| 10.5 | 209.8 | GO:1902562 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 10.2 | 51.1 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 10.1 | 151.8 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 10.1 | 80.6 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 10.1 | 251.7 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 10.0 | 79.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 9.9 | 197.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 9.6 | 172.5 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 9.5 | 104.7 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 9.5 | 38.0 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 9.3 | 27.9 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 9.0 | 71.6 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 8.9 | 133.8 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 8.9 | 142.2 | GO:0051233 | spindle midzone(GO:0051233) |
| 8.6 | 77.6 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 8.5 | 144.4 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 8.4 | 160.3 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 7.9 | 408.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 7.8 | 15.7 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 7.3 | 51.3 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 7.2 | 21.7 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 7.2 | 107.3 | GO:0005685 | U1 snRNP(GO:0005685) |
| 7.1 | 35.7 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 7.1 | 340.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 7.1 | 14.2 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 7.0 | 14.1 | GO:0000805 | X chromosome(GO:0000805) |
| 7.0 | 63.2 | GO:0070552 | BRISC complex(GO:0070552) |
| 7.0 | 70.0 | GO:0043203 | axon hillock(GO:0043203) |
| 6.8 | 27.2 | GO:0005687 | U4 snRNP(GO:0005687) |
| 6.6 | 19.7 | GO:0033167 | ARC complex(GO:0033167) |
| 6.5 | 1230.2 | GO:0000793 | condensed chromosome(GO:0000793) |
| 6.5 | 64.7 | GO:0071439 | clathrin complex(GO:0071439) |
| 6.4 | 51.6 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 6.3 | 69.2 | GO:0070449 | elongin complex(GO:0070449) |
| 6.2 | 37.1 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 6.1 | 61.4 | GO:0090543 | Flemming body(GO:0090543) |
| 6.1 | 177.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 6.1 | 79.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 6.1 | 67.1 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 6.0 | 54.2 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 6.0 | 190.5 | GO:0005876 | spindle microtubule(GO:0005876) |
| 5.9 | 29.7 | GO:0005869 | dynactin complex(GO:0005869) |
| 5.9 | 35.6 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 5.9 | 35.5 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 5.7 | 149.2 | GO:0005916 | fascia adherens(GO:0005916) |
| 5.7 | 34.1 | GO:0097422 | tubular endosome(GO:0097422) |
| 5.6 | 486.1 | GO:0005643 | nuclear pore(GO:0005643) |
| 5.4 | 65.2 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 5.4 | 65.1 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 5.3 | 42.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 5.1 | 25.6 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 5.0 | 19.9 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 5.0 | 69.3 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 4.7 | 407.4 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 4.6 | 32.3 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 4.6 | 151.6 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 4.4 | 308.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 4.4 | 8.7 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 4.3 | 56.3 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 4.2 | 212.3 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 4.2 | 75.7 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 4.2 | 33.4 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 4.0 | 413.0 | GO:0031970 | organelle envelope lumen(GO:0031970) |
| 3.9 | 23.6 | GO:1990635 | proximal dendrite(GO:1990635) |
| 3.9 | 62.8 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 3.9 | 42.7 | GO:0005638 | lamin filament(GO:0005638) |
| 3.9 | 15.4 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 3.8 | 594.4 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 3.8 | 53.1 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 3.8 | 30.1 | GO:0070187 | telosome(GO:0070187) |
| 3.7 | 11.0 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 3.7 | 22.0 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 3.6 | 39.8 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 3.6 | 60.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 3.5 | 17.4 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 3.5 | 69.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 3.3 | 13.3 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 3.3 | 76.0 | GO:0000776 | kinetochore(GO:0000776) |
| 3.3 | 9.9 | GO:0031515 | tRNA (m1A) methyltransferase complex(GO:0031515) |
| 3.3 | 283.5 | GO:0035580 | specific granule lumen(GO:0035580) |
| 3.2 | 9.6 | GO:0097637 | intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
| 3.1 | 121.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 3.0 | 12.1 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 2.9 | 300.3 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 2.9 | 11.8 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 2.8 | 33.4 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 2.8 | 52.9 | GO:1902555 | endoribonuclease complex(GO:1902555) |
| 2.7 | 59.2 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 2.6 | 72.0 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 2.5 | 25.4 | GO:0097225 | sperm midpiece(GO:0097225) |
| 2.5 | 12.6 | GO:0070826 | paraferritin complex(GO:0070826) |
| 2.4 | 17.1 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 2.4 | 19.2 | GO:0016600 | flotillin complex(GO:0016600) |
| 2.4 | 28.6 | GO:0071203 | WASH complex(GO:0071203) |
| 2.4 | 11.9 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 2.3 | 53.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 2.3 | 75.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 2.3 | 11.4 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 2.3 | 70.6 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 2.3 | 6.8 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 2.2 | 8.8 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 2.1 | 171.5 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 2.1 | 38.4 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 2.1 | 86.2 | GO:0016592 | mediator complex(GO:0016592) |
| 2.1 | 18.9 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 2.1 | 134.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 2.1 | 10.3 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 2.1 | 142.5 | GO:0005811 | lipid particle(GO:0005811) |
| 2.1 | 80.5 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 2.0 | 34.8 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 2.0 | 840.0 | GO:0005635 | nuclear envelope(GO:0005635) |
| 2.0 | 15.9 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 2.0 | 21.7 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 2.0 | 45.0 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 2.0 | 29.4 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 1.9 | 58.6 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 1.9 | 13.2 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 1.9 | 14.8 | GO:0034464 | BBSome(GO:0034464) |
| 1.8 | 52.1 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 1.8 | 30.2 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 1.7 | 15.4 | GO:0097433 | dense body(GO:0097433) |
| 1.6 | 203.2 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 1.6 | 16.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 1.6 | 365.0 | GO:0034774 | secretory granule lumen(GO:0034774) |
| 1.6 | 17.1 | GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178) |
| 1.5 | 30.2 | GO:0001891 | phagocytic cup(GO:0001891) |
| 1.5 | 8.9 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 1.4 | 34.2 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 1.4 | 5.5 | GO:0000322 | storage vacuole(GO:0000322) |
| 1.4 | 12.2 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 1.3 | 8.1 | GO:0043073 | germ cell nucleus(GO:0043073) |
| 1.3 | 133.9 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 1.3 | 12.6 | GO:0061574 | ASAP complex(GO:0061574) |
| 1.2 | 22.4 | GO:1990391 | DNA repair complex(GO:1990391) |
| 1.2 | 18.6 | GO:0000145 | exocyst(GO:0000145) |
| 1.2 | 2.4 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 1.2 | 94.0 | GO:0000922 | spindle pole(GO:0000922) |
| 1.1 | 5.7 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 1.1 | 22.2 | GO:0032040 | small-subunit processome(GO:0032040) |
| 1.1 | 37.8 | GO:0015030 | Cajal body(GO:0015030) |
| 1.1 | 12.7 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.9 | 11.1 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.9 | 19.5 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.9 | 13.0 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.9 | 7.7 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.8 | 33.5 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.7 | 3.0 | GO:0030684 | preribosome(GO:0030684) |
| 0.7 | 18.6 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.7 | 11.4 | GO:0097546 | ciliary base(GO:0097546) |
| 0.7 | 63.1 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.7 | 4.2 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.7 | 6.1 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.7 | 4.6 | GO:0031415 | NatA complex(GO:0031415) |
| 0.6 | 6.1 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.6 | 151.2 | GO:1990904 | ribonucleoprotein complex(GO:1990904) |
| 0.6 | 17.1 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.6 | 3.4 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.6 | 10.1 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.6 | 84.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.6 | 57.0 | GO:0016605 | PML body(GO:0016605) |
| 0.5 | 1.1 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.5 | 2.2 | GO:0022624 | proteasome accessory complex(GO:0022624) |
| 0.5 | 3.7 | GO:0032039 | integrator complex(GO:0032039) |
| 0.5 | 5.2 | GO:0097346 | INO80-type complex(GO:0097346) |
| 0.5 | 1.4 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.5 | 34.6 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.5 | 41.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.5 | 2.3 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.4 | 12.8 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.4 | 19.7 | GO:0030315 | T-tubule(GO:0030315) |
| 0.4 | 122.7 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.4 | 14.3 | GO:0045095 | keratin filament(GO:0045095) |
| 0.4 | 21.4 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.4 | 0.7 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.4 | 3.0 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.3 | 1.4 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.3 | 1.3 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.3 | 2.0 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.3 | 1.2 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.3 | 25.6 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.3 | 108.5 | GO:0005694 | chromosome(GO:0005694) |
| 0.3 | 132.7 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.3 | 14.1 | GO:0005902 | microvillus(GO:0005902) |
| 0.2 | 16.6 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.2 | 3.8 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.2 | 6.7 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.2 | 5.4 | GO:0032420 | stereocilium(GO:0032420) |
| 0.2 | 5.9 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 1.2 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.2 | 0.6 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.2 | 3.0 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 31.3 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 6.6 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 83.8 | GO:0015630 | microtubule cytoskeleton(GO:0015630) |
| 0.1 | 0.6 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 0.5 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.2 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 0.0 | 0.1 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.0 | 0.6 | GO:0045178 | basal part of cell(GO:0045178) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 196.0 | 1176.0 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 138.3 | 553.1 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 113.0 | 339.0 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 102.2 | 409.0 | GO:0042282 | hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282) |
| 79.8 | 239.3 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 69.5 | 208.4 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 60.5 | 242.1 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 54.0 | 810.7 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 49.5 | 445.6 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 48.1 | 192.6 | GO:0004488 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 47.2 | 330.7 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 46.4 | 278.3 | GO:0004310 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 44.5 | 133.4 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 42.6 | 170.4 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 41.7 | 249.9 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 41.3 | 206.3 | GO:0004161 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 37.2 | 111.6 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
| 36.8 | 220.9 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 34.9 | 348.9 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 34.1 | 136.4 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 30.9 | 185.2 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 30.4 | 152.1 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 29.7 | 148.5 | GO:0032143 | single thymine insertion binding(GO:0032143) |
| 29.0 | 87.1 | GO:0047012 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012) |
| 29.0 | 87.1 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 28.9 | 86.8 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 28.1 | 337.2 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 26.1 | 313.5 | GO:0035173 | histone kinase activity(GO:0035173) |
| 25.9 | 103.7 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 25.0 | 124.8 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 24.7 | 197.9 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 24.2 | 72.6 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 24.1 | 169.0 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 23.4 | 187.2 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 23.4 | 93.4 | GO:0004001 | adenosine kinase activity(GO:0004001) |
| 23.0 | 459.2 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 20.7 | 82.9 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 20.6 | 288.2 | GO:0046790 | virion binding(GO:0046790) |
| 20.1 | 60.4 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 19.8 | 257.0 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 18.7 | 878.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 18.6 | 130.1 | GO:0097506 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 18.5 | 313.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 18.2 | 54.6 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 18.1 | 108.4 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 17.4 | 52.2 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 17.4 | 729.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 17.3 | 69.2 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 17.1 | 51.3 | GO:0001002 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
| 17.1 | 119.7 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 16.6 | 49.8 | GO:0015137 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 16.6 | 49.8 | GO:0000248 | C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704) |
| 15.7 | 94.2 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 15.4 | 77.1 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 15.1 | 30.2 | GO:0046979 | TAP2 binding(GO:0046979) |
| 15.1 | 105.6 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 15.0 | 30.0 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 14.4 | 43.2 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 14.3 | 573.3 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 14.2 | 71.0 | GO:0004619 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 13.7 | 795.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 13.7 | 95.7 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 13.6 | 54.6 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 13.5 | 40.5 | GO:0052794 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 13.4 | 133.9 | GO:0042731 | PH domain binding(GO:0042731) |
| 13.3 | 93.4 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 13.1 | 603.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 12.9 | 38.7 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 12.3 | 147.9 | GO:0015266 | protein channel activity(GO:0015266) |
| 12.1 | 72.6 | GO:0032296 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 12.0 | 335.9 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 12.0 | 71.8 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 11.9 | 47.5 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 11.8 | 142.1 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 11.8 | 188.4 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 11.6 | 58.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 11.5 | 91.7 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 11.3 | 34.0 | GO:0048030 | disaccharide binding(GO:0048030) |
| 11.3 | 79.2 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 11.2 | 33.5 | GO:0070538 | oleic acid binding(GO:0070538) |
| 11.0 | 33.0 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 10.9 | 43.4 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 10.7 | 42.7 | GO:0030622 | U4atac snRNA binding(GO:0030622) |
| 10.5 | 52.6 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 10.3 | 51.3 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 10.1 | 30.3 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 10.1 | 50.3 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 10.0 | 129.4 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 9.7 | 38.7 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 9.6 | 288.2 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 9.4 | 66.1 | GO:0046972 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 9.3 | 46.7 | GO:1990446 | snRNA stem-loop binding(GO:0035614) U1 snRNP binding(GO:1990446) |
| 9.3 | 129.9 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 9.2 | 45.9 | GO:0016936 | galactoside binding(GO:0016936) |
| 9.0 | 89.5 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 8.8 | 96.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 8.6 | 77.3 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 8.5 | 34.0 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 8.4 | 92.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 8.3 | 41.7 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 8.3 | 16.6 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 8.2 | 48.9 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 8.1 | 113.1 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 7.9 | 63.0 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 7.9 | 109.9 | GO:0031386 | protein tag(GO:0031386) |
| 7.8 | 31.4 | GO:0043515 | kinetochore binding(GO:0043515) |
| 7.8 | 54.6 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 7.7 | 23.2 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 7.7 | 146.5 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 7.6 | 22.9 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 7.6 | 212.7 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 7.6 | 227.6 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 7.4 | 22.3 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 7.4 | 140.4 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 7.3 | 36.6 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 7.3 | 29.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 7.3 | 166.8 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 7.2 | 129.1 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 7.1 | 28.6 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 7.1 | 42.7 | GO:0004359 | glutaminase activity(GO:0004359) |
| 7.1 | 28.3 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 6.9 | 319.7 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 6.9 | 69.3 | GO:0055104 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 6.9 | 41.6 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 6.8 | 1161.2 | GO:0042393 | histone binding(GO:0042393) |
| 6.7 | 20.1 | GO:0034416 | bisphosphoglycerate phosphatase activity(GO:0034416) |
| 6.6 | 26.5 | GO:0070905 | serine binding(GO:0070905) |
| 6.5 | 19.5 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 6.4 | 19.2 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 6.2 | 31.2 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 6.1 | 67.5 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 6.1 | 317.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 6.1 | 36.6 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 6.0 | 18.1 | GO:0055100 | adiponectin binding(GO:0055100) |
| 5.9 | 172.0 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 5.9 | 29.6 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 5.9 | 93.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 5.8 | 40.8 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 5.8 | 34.9 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 5.8 | 11.6 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 5.8 | 51.9 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 5.7 | 62.7 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 5.7 | 28.5 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 5.5 | 22.1 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 5.4 | 200.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 5.4 | 129.6 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 5.3 | 69.0 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 5.3 | 52.9 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 5.2 | 57.4 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
| 5.1 | 25.7 | GO:0031544 | peptidyl-proline 3-dioxygenase activity(GO:0031544) |
| 5.1 | 20.3 | GO:0003983 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 5.0 | 20.1 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 5.0 | 15.0 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 4.9 | 19.8 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 4.9 | 9.7 | GO:0070404 | NADH binding(GO:0070404) |
| 4.7 | 18.9 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 4.7 | 99.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 4.7 | 14.1 | GO:0052836 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 4.7 | 233.4 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 4.6 | 74.4 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 4.6 | 83.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 4.5 | 18.1 | GO:0015563 | uptake transmembrane transporter activity(GO:0015563) |
| 4.5 | 26.9 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 4.5 | 35.7 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 4.4 | 31.0 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 4.4 | 26.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 4.3 | 80.9 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 4.2 | 452.0 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 4.1 | 12.4 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 4.1 | 140.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 4.1 | 20.5 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 4.1 | 20.5 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
| 4.0 | 32.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 3.9 | 23.2 | GO:0036310 | annealing helicase activity(GO:0036310) annealing activity(GO:0097617) |
| 3.9 | 228.4 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 3.9 | 15.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 3.9 | 15.4 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 3.8 | 95.8 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 3.8 | 26.7 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 3.8 | 26.3 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 3.7 | 48.0 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 3.6 | 10.9 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 3.6 | 188.4 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) |
| 3.6 | 97.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 3.6 | 88.8 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 3.6 | 46.2 | GO:0031491 | nucleosome binding(GO:0031491) |
| 3.5 | 206.3 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 3.5 | 20.9 | GO:0016274 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 3.5 | 27.6 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 3.4 | 165.4 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 3.4 | 10.3 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 3.4 | 44.6 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 3.4 | 51.4 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 3.4 | 20.5 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 3.4 | 23.8 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 3.4 | 6.7 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 3.4 | 30.2 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 3.3 | 13.3 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
| 3.3 | 9.9 | GO:0016429 | tRNA (adenine-N1-)-methyltransferase activity(GO:0016429) |
| 3.3 | 33.0 | GO:0070628 | proteasome binding(GO:0070628) |
| 3.2 | 83.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 3.2 | 15.8 | GO:0004122 | cystathionine beta-synthase activity(GO:0004122) |
| 3.1 | 180.9 | GO:0002039 | p53 binding(GO:0002039) |
| 3.1 | 28.0 | GO:0030274 | LIM domain binding(GO:0030274) |
| 3.1 | 365.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 3.0 | 9.1 | GO:0033265 | choline binding(GO:0033265) |
| 3.0 | 3.0 | GO:0005055 | laminin receptor activity(GO:0005055) |
| 2.9 | 8.8 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 2.9 | 11.6 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 2.9 | 125.7 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 2.8 | 11.4 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 2.8 | 44.1 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 2.7 | 40.2 | GO:0005521 | lamin binding(GO:0005521) |
| 2.7 | 32.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 2.7 | 56.0 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 2.7 | 8.0 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 2.7 | 29.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 2.6 | 2.6 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 2.6 | 21.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 2.6 | 13.2 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
| 2.6 | 30.8 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 2.5 | 20.3 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 2.5 | 100.6 | GO:0043236 | laminin binding(GO:0043236) |
| 2.5 | 12.6 | GO:0015093 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 2.5 | 74.4 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 2.5 | 12.4 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 2.5 | 24.6 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 2.5 | 58.9 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 2.4 | 19.4 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 2.4 | 7.2 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 2.4 | 95.8 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 2.4 | 26.0 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 2.4 | 11.8 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 2.3 | 23.5 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 2.3 | 84.1 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 2.3 | 43.9 | GO:0005537 | mannose binding(GO:0005537) |
| 2.3 | 9.2 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 2.3 | 36.4 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 2.3 | 40.6 | GO:0030515 | snoRNA binding(GO:0030515) |
| 2.2 | 11.2 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 2.2 | 8.9 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 2.2 | 174.0 | GO:0004386 | helicase activity(GO:0004386) |
| 2.2 | 10.9 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 2.1 | 45.0 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 2.1 | 49.0 | GO:0070840 | dynein complex binding(GO:0070840) |
| 2.1 | 133.8 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 2.1 | 4.1 | GO:0000035 | acyl binding(GO:0000035) |
| 2.1 | 18.7 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 2.1 | 415.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 2.0 | 6.1 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 2.0 | 59.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 2.0 | 22.4 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 2.0 | 2.0 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 2.0 | 22.3 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 2.0 | 56.7 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 2.0 | 12.1 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 2.0 | 33.9 | GO:0016891 | tRNA-specific ribonuclease activity(GO:0004549) endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
| 2.0 | 23.9 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 1.9 | 44.8 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 1.9 | 174.4 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 1.9 | 79.9 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 1.9 | 13.0 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 1.8 | 12.9 | GO:0051400 | BH domain binding(GO:0051400) |
| 1.8 | 43.7 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
| 1.8 | 12.7 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 1.8 | 5.4 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 1.8 | 14.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 1.8 | 16.2 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 1.8 | 93.4 | GO:0016859 | cis-trans isomerase activity(GO:0016859) |
| 1.8 | 3.6 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 1.7 | 17.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 1.7 | 10.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 1.7 | 5.2 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 1.7 | 30.2 | GO:0097016 | L27 domain binding(GO:0097016) |
| 1.6 | 14.8 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 1.6 | 3.3 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 1.6 | 12.8 | GO:0015925 | galactosidase activity(GO:0015925) |
| 1.6 | 41.1 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 1.6 | 11.0 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 1.6 | 6.2 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 1.5 | 6.2 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
| 1.5 | 38.5 | GO:0008143 | poly(A) binding(GO:0008143) |
| 1.5 | 52.3 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 1.5 | 6.1 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 1.5 | 48.8 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 1.5 | 4.5 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 1.5 | 4.4 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 1.4 | 11.5 | GO:0050733 | RS domain binding(GO:0050733) |
| 1.4 | 11.5 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 1.4 | 24.0 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 1.4 | 119.3 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 1.4 | 88.8 | GO:0005507 | copper ion binding(GO:0005507) |
| 1.4 | 16.4 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 1.4 | 9.5 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 1.3 | 10.8 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 1.3 | 10.3 | GO:0008312 | 7S RNA binding(GO:0008312) |
| 1.3 | 53.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 1.2 | 49.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 1.2 | 42.6 | GO:0019894 | kinesin binding(GO:0019894) |
| 1.2 | 13.0 | GO:0004659 | prenyltransferase activity(GO:0004659) |
| 1.2 | 29.4 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 1.2 | 4.7 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 1.2 | 14.0 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 1.1 | 3.4 | GO:0071566 | UFM1 activating enzyme activity(GO:0071566) |
| 1.1 | 44.3 | GO:0050699 | WW domain binding(GO:0050699) |
| 1.1 | 19.3 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 1.1 | 4.3 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 1.1 | 23.4 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 1.1 | 3.2 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 1.1 | 2.1 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 1.0 | 8.3 | GO:0089720 | caspase binding(GO:0089720) |
| 1.0 | 7.1 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 1.0 | 57.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 1.0 | 9.8 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 1.0 | 26.3 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 1.0 | 3.9 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 1.0 | 16.4 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 1.0 | 71.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.9 | 4.6 | GO:0004473 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948) |
| 0.9 | 96.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.9 | 20.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.9 | 11.6 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.9 | 12.0 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.8 | 14.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.8 | 10.0 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.8 | 16.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.8 | 32.3 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.8 | 19.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.7 | 3.0 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.7 | 6.6 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.7 | 2.9 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.7 | 10.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.7 | 12.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.7 | 7.6 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.7 | 44.7 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.7 | 28.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.7 | 3.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.7 | 2.0 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.7 | 3.3 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.7 | 9.8 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.6 | 3.7 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.6 | 8.6 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.6 | 24.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.6 | 8.9 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.6 | 4.6 | GO:0032182 | ubiquitin-like protein binding(GO:0032182) |
| 0.6 | 6.7 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.6 | 3.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.6 | 3.3 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.6 | 3.3 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.5 | 10.2 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.5 | 3.7 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.5 | 2.6 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 0.5 | 36.1 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.5 | 16.2 | GO:0043531 | ADP binding(GO:0043531) |
| 0.5 | 2.5 | GO:0010340 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.5 | 9.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.5 | 12.0 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.5 | 2.0 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.5 | 2.3 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.5 | 98.8 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.5 | 1.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.5 | 3.2 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.5 | 6.8 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.5 | 5.5 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.5 | 1.8 | GO:0004335 | galactokinase activity(GO:0004335) |
| 0.4 | 8.9 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.4 | 3.5 | GO:0050694 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.4 | 1.7 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.4 | 480.5 | GO:0003723 | RNA binding(GO:0003723) |
| 0.4 | 1.2 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
| 0.4 | 5.3 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.4 | 0.8 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.4 | 5.6 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.4 | 1.5 | GO:0019862 | IgA binding(GO:0019862) |
| 0.4 | 1.1 | GO:0034736 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 0.4 | 3.0 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.4 | 1.1 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.3 | 46.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.3 | 1.0 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.3 | 1.0 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.3 | 1.6 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.3 | 74.8 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.3 | 2.2 | GO:0004996 | thyroid-stimulating hormone receptor activity(GO:0004996) |
| 0.3 | 1.7 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.3 | 0.3 | GO:0015556 | C4-dicarboxylate transmembrane transporter activity(GO:0015556) |
| 0.3 | 1.3 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.2 | 2.4 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.2 | 1.9 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.2 | 2.0 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.2 | 39.9 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.2 | 2.0 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.2 | 1.1 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.2 | 0.8 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.2 | 6.7 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.2 | 0.6 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.2 | 1.2 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.2 | 3.4 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 0.2 | 0.9 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.2 | 1.3 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
| 0.2 | 1.9 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
| 0.2 | 0.5 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.2 | 1.6 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
| 0.1 | 2.1 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.1 | 0.8 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 3.0 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 1.9 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 0.8 | GO:0019863 | IgE binding(GO:0019863) |
| 0.1 | 0.5 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.1 | 0.3 | GO:0097259 | tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 0.1 | 0.3 | GO:0030290 | sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428) |
| 0.1 | 2.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.5 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.1 | 0.5 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.1 | 0.7 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 0.6 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 0.6 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.1 | GO:0004060 | arylamine N-acetyltransferase activity(GO:0004060) |
| 0.0 | 0.8 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.2 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.5 | GO:0004536 | deoxyribonuclease activity(GO:0004536) |
| 0.0 | 0.2 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.3 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.0 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 31.9 | 2421.6 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 30.7 | 706.2 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 23.9 | 1580.0 | PID PLK1 PATHWAY | PLK1 signaling events |
| 14.1 | 674.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 14.0 | 502.5 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 13.3 | 372.2 | PID BARD1 PATHWAY | BARD1 signaling events |
| 11.5 | 379.7 | PID AURORA A PATHWAY | Aurora A signaling |
| 10.7 | 245.4 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 10.0 | 459.6 | PID ATR PATHWAY | ATR signaling pathway |
| 8.9 | 285.0 | PID MYC PATHWAY | C-MYC pathway |
| 8.4 | 819.3 | PID E2F PATHWAY | E2F transcription factor network |
| 6.0 | 23.9 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 5.5 | 322.2 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 5.4 | 369.2 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 5.2 | 294.9 | PID P53 REGULATION PATHWAY | p53 pathway |
| 4.9 | 98.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 4.5 | 111.9 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 4.4 | 311.7 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 4.1 | 16.5 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 3.4 | 291.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 3.3 | 86.7 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 3.0 | 248.2 | PID P73PATHWAY | p73 transcription factor network |
| 2.9 | 79.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 2.9 | 422.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 2.8 | 93.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 2.6 | 23.4 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 2.6 | 43.7 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 2.4 | 120.9 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 2.3 | 36.1 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 2.2 | 143.3 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 2.2 | 56.3 | PID ARF 3PATHWAY | Arf1 pathway |
| 2.1 | 100.1 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 1.9 | 75.1 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 1.7 | 68.6 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 1.6 | 118.4 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 1.6 | 91.6 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 1.4 | 22.8 | PID ATM PATHWAY | ATM pathway |
| 1.4 | 101.4 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 1.2 | 10.0 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 1.2 | 22.4 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 1.2 | 48.0 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 1.2 | 19.4 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 1.2 | 32.4 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 1.2 | 20.3 | PID BCR 5PATHWAY | BCR signaling pathway |
| 1.2 | 37.8 | PID RHOA PATHWAY | RhoA signaling pathway |
| 1.2 | 33.6 | PID FOXO PATHWAY | FoxO family signaling |
| 1.1 | 9.9 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 1.0 | 30.2 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 1.0 | 49.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.9 | 12.6 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.9 | 15.5 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.8 | 14.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.7 | 22.0 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.7 | 34.1 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.6 | 10.9 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.6 | 30.6 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.6 | 7.6 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.6 | 28.4 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.6 | 20.8 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.5 | 23.0 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.5 | 12.1 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.5 | 12.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.4 | 21.0 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.4 | 10.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.4 | 4.0 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.4 | 15.5 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.4 | 6.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.3 | 23.6 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.3 | 11.7 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.3 | 2.3 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.2 | 61.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 7.7 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.2 | 1.1 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.2 | 4.1 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.2 | 1.7 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 0.9 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 1.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 2.8 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 2.9 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.4 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 97.6 | 487.9 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 58.0 | 58.0 | REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 57.5 | 862.5 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 56.8 | 1648.6 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 46.0 | 1287.7 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 41.0 | 1638.5 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 40.5 | 607.5 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 40.3 | 604.4 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 33.4 | 33.4 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 31.4 | 440.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 24.4 | 195.1 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 23.9 | 550.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 21.1 | 315.8 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 19.2 | 536.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 18.3 | 347.4 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 17.9 | 321.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 16.2 | 259.5 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 15.6 | 218.0 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 13.5 | 554.0 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 12.6 | 993.2 | REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
| 12.5 | 237.0 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 12.4 | 247.5 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 12.2 | 230.9 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 11.7 | 105.7 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 11.4 | 34.3 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 11.1 | 100.3 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 10.2 | 50.9 | REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
| 9.3 | 46.3 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 8.8 | 265.2 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 8.7 | 746.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 8.3 | 198.3 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 8.2 | 98.6 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 7.6 | 76.1 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 7.5 | 120.5 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 7.4 | 206.7 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 7.3 | 1105.9 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 6.9 | 96.3 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 6.8 | 591.0 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 6.7 | 186.2 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 6.6 | 66.3 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 6.5 | 72.0 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 6.5 | 453.5 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 6.5 | 71.0 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 6.4 | 32.2 | REACTOME M G1 TRANSITION | Genes involved in M/G1 Transition |
| 6.1 | 42.5 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 6.1 | 230.1 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 5.8 | 81.7 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 5.5 | 171.2 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 5.5 | 132.2 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 5.5 | 99.0 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 5.3 | 237.7 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 4.7 | 41.9 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 4.5 | 99.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 4.4 | 87.7 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 4.2 | 202.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 4.1 | 120.1 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 3.9 | 117.9 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 3.8 | 34.1 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 3.8 | 30.1 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 3.6 | 123.0 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 3.5 | 111.8 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 3.4 | 57.8 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 3.3 | 100.1 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 3.3 | 56.1 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 3.1 | 49.5 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 3.0 | 158.7 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 2.9 | 49.5 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 2.8 | 44.2 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 2.6 | 223.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 2.6 | 75.3 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 2.5 | 170.9 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 2.5 | 69.5 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 2.4 | 24.4 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 2.2 | 500.5 | REACTOME TRANSLATION | Genes involved in Translation |
| 2.0 | 66.8 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 1.9 | 13.5 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 1.9 | 84.7 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 1.9 | 28.7 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 1.7 | 12.1 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 1.5 | 89.2 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 1.5 | 28.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 1.4 | 11.5 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 1.4 | 35.6 | REACTOME GLOBAL GENOMIC NER GG NER | Genes involved in Global Genomic NER (GG-NER) |
| 1.4 | 4.1 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 1.4 | 36.9 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 1.3 | 31.7 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 1.2 | 13.4 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 1.2 | 10.4 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 1.1 | 66.7 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 1.1 | 70.4 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 1.1 | 54.3 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 1.1 | 139.3 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 1.1 | 11.0 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 1.1 | 27.5 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 1.1 | 3.3 | REACTOME INTEGRATION OF ENERGY METABOLISM | Genes involved in Integration of energy metabolism |
| 1.1 | 28.2 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 1.0 | 15.9 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 1.0 | 2.9 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.9 | 17.4 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.9 | 25.0 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.8 | 15.5 | REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| 0.8 | 10.0 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.8 | 92.6 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.7 | 11.0 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.7 | 12.2 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.7 | 27.0 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.6 | 19.7 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.6 | 81.5 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.5 | 5.7 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.5 | 22.8 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.5 | 18.3 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.4 | 6.5 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.3 | 7.1 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.3 | 5.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.3 | 12.0 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.3 | 2.0 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.3 | 31.6 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.3 | 2.5 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.3 | 9.1 | REACTOME APOPTOTIC EXECUTION PHASE | Genes involved in Apoptotic execution phase |
| 0.2 | 8.4 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.2 | 5.9 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.2 | 6.6 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.2 | 2.4 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.2 | 8.4 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 1.8 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 4.7 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 2.3 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 24.4 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |
| 0.1 | 3.8 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.1 | 3.0 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 6.2 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 1.1 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.1 | 0.8 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 0.6 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |