ISMARA results: ZBTB14

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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZBTB14

Z-value: 1.90

Motif logo

Transcription factors associated with ZBTB14

Gene Symbol	Gene ID	Gene Info
ZBTB14 Ensembl NCBI GeneCards UniProt	ENSG00000198081.11	ZBTB14

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZBTB14	hg38_v1_chr18_-_5296139_5296195	0.19	4.9e-03	Click!

Activity profile of ZBTB14 motif

Sorted Z-values of ZBTB14 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB14

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr16_+_1989949 Show fit	51.07	ENST00000248121.7 ENST00000618464.1	SYNGR3 Ensembl NCBI GeneCards UniProt Show fit	synaptogyrin 3
chr15_+_91100194 Show fit	40.20	ENST00000394232.6	SV2B Ensembl NCBI GeneCards UniProt Show fit	synaptic vesicle glycoprotein 2B
chr4_+_157220654 Show fit	37.86	ENST00000393815.6	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr4_+_157220691 Show fit	37.01	ENST00000509417.5 ENST00000645636.1 ENST00000296526.12 ENST00000264426.14	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr1_+_204828643 Show fit	35.97	ENST00000339876.11 ENST00000680427.1 ENST00000403080.5 ENST00000513543.6 ENST00000430393.7	NFASC Ensembl NCBI GeneCards UniProt Show fit	neurofascin
chr9_+_17579059 Show fit	35.38	ENST00000380607.5	SH3GL2 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing GRB2 like 2, endophilin A1
chrX_+_38561530 Show fit	32.56	ENST00000378482.7 ENST00000286824.6	TSPAN7 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 7
chr16_+_56589521 Show fit	31.87	ENST00000200691.5 ENST00000570176.1	MT3 Ensembl NCBI GeneCards UniProt Show fit	metallothionein 3
chr8_+_24914942 Show fit	30.48	ENST00000433454.3	NEFM Ensembl NCBI GeneCards UniProt Show fit	neurofilament medium
chr1_-_9823953 Show fit	30.14	ENST00000377298.9 ENST00000361311.4	CLSTN1 Ensembl NCBI GeneCards UniProt Show fit	calsyntenin 1
chr3_-_133895577 Show fit	29.25	ENST00000543906.5	RAB6B Ensembl NCBI GeneCards UniProt Show fit	RAB6B, member RAS oncogene family
chr17_+_45894515 Show fit	27.68	ENST00000680674.1 ENST00000535772.6 ENST00000351559.10 ENST00000262410.10 ENST00000344290.10	MAPT Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein tau
chr12_-_123972709 Show fit	27.45	ENST00000545891.5	CCDC92 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 92
chr7_-_44325653 Show fit	27.21	ENST00000440254.6	CAMK2B Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II beta
chr16_+_172869 Show fit	27.07	ENST00000251595.11 ENST00000397806.1 ENST00000484216.1	HBA2 Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit alpha 2
chr15_+_74130551 Show fit	26.78	ENST00000453268.3	ISLR2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily containing leucine rich repeat 2
chr16_+_176659 Show fit	25.85	ENST00000320868.9 ENST00000397797.1	HBA1 Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit alpha 1
chr17_+_45894644 Show fit	25.55	ENST00000680542.1 ENST00000334239.12 ENST00000446361.7	MAPT Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein tau
chr18_-_77132771 Show fit	25.51	ENST00000355994.7 ENST00000579129.5	MBP Ensembl NCBI GeneCards UniProt Show fit	myelin basic protein
chr22_-_31346143 Show fit	25.41	ENST00000405309.7 ENST00000351933.8	PATZ1 Ensembl NCBI GeneCards UniProt Show fit	POZ/BTB and AT hook containing zinc finger 1
chr7_-_44325490 Show fit	24.95	ENST00000350811.7	CAMK2B Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II beta
chr11_-_6419394 Show fit	24.85	ENST00000311051.7	APBB1 Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein binding family B member 1
chr2_-_175005357 Show fit	24.77	ENST00000409156.7 ENST00000444573.2 ENST00000409900.9	CHN1 Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr11_-_6419051 Show fit	24.55	ENST00000299402.10 ENST00000532020.2 ENST00000609360.6 ENST00000389906.6	APBB1 Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein binding family B member 1
chr2_+_79512993 Show fit	24.20	ENST00000496558.5 ENST00000451966.5 ENST00000402739.9 ENST00000629316.2	CTNNA2 Ensembl NCBI GeneCards UniProt Show fit	catenin alpha 2
chr12_-_123972824 Show fit	23.75	ENST00000238156.8 ENST00000545037.1	CCDC92 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 92
chr17_+_46590669 Show fit	23.34	ENST00000398238.8	NSF Ensembl NCBI GeneCards UniProt Show fit	N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr7_-_44325421 Show fit	23.02	ENST00000395747.6 ENST00000347193.8 ENST00000346990.8 ENST00000258682.10 ENST00000353625.8 ENST00000421607.1 ENST00000424197.5	CAMK2B Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II beta
chr3_-_133895867 Show fit	21.80	ENST00000285208.9	RAB6B Ensembl NCBI GeneCards UniProt Show fit	RAB6B, member RAS oncogene family
chr7_+_121873089 Show fit	21.76	ENST00000651065.1	PTPRZ1 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type Z1
chr14_+_99971442 Show fit	21.73	ENST00000402714.6	EVL Ensembl NCBI GeneCards UniProt Show fit	Enah/Vasp-like
chr1_-_31764035 Show fit	20.92	ENST00000373655.6	ADGRB2 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor B2
chr4_+_7043315 Show fit	20.81	ENST00000310074.8 ENST00000512388.1	TADA2B Ensembl NCBI GeneCards UniProt Show fit	transcriptional adaptor 2B
chr7_+_45574358 Show fit	20.60	ENST00000297323.12	ADCY1 Ensembl NCBI GeneCards UniProt Show fit	adenylate cyclase 1
chr12_-_124567464 Show fit	20.47	ENST00000458234.5	NCOR2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor corepressor 2
chr16_+_6483379 Show fit	20.01	ENST00000552089.5	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr14_+_92323154 Show fit	19.78	ENST00000532405.6 ENST00000676001.1 ENST00000531433.5	SLC24A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 24 member 4
chr16_+_5033923 Show fit	19.38	ENST00000683433.1 ENST00000682020.1 ENST00000682985.1 ENST00000682327.1 ENST00000588623.5	ALG1 Ensembl NCBI GeneCards UniProt Show fit	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
chr16_+_6483728 Show fit	19.32	ENST00000675459.1 ENST00000551752.5	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr6_+_31897775 Show fit	19.13	ENST00000469372.5 ENST00000497706.5	C2 Ensembl NCBI GeneCards UniProt Show fit	complement C2
chr16_+_56191476 Show fit	18.84	ENST00000262493.12	GNAO1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha o1
chr20_+_17227020 Show fit	18.47	ENST00000262545.7 ENST00000536609.1	PCSK2 Ensembl NCBI GeneCards UniProt Show fit	proprotein convertase subtilisin/kexin type 2
chr11_-_66568524 Show fit	18.46	ENST00000679160.1 ENST00000678305.1 ENST00000310325.10 ENST00000677896.1 ENST00000677587.1 ENST00000679347.1 ENST00000677005.1 ENST00000678872.1 ENST00000679024.1 ENST00000678471.1 ENST00000524994.6	CTSF Ensembl NCBI GeneCards UniProt Show fit	cathepsin F
chr11_+_72080803 Show fit	18.39	ENST00000423494.6 ENST00000539587.6 ENST00000536917.2 ENST00000538478.5 ENST00000324866.11 ENST00000643715.1 ENST00000439209.5	LRTOMT Ensembl NCBI GeneCards UniProt Show fit ENSG00000284922.2 Ensembl NCBI GeneCards UniProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing leucine rich transmembrane and O-methyltransferase domain containing
chr7_+_121873152 Show fit	18.32	ENST00000650826.1 ENST00000650728.1 ENST00000393386.7 ENST00000651390.1 ENST00000651842.1 ENST00000650681.1	PTPRZ1 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type Z1
chr1_-_31763866 Show fit	18.28	ENST00000398547.5	ADGRB2 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor B2
chr10_+_103277129 Show fit	18.13	ENST00000369849.9	INA Ensembl NCBI GeneCards UniProt Show fit	internexin neuronal intermediate filament protein alpha
chr20_-_51768327 Show fit	17.94	ENST00000311637.9 ENST00000338821.6	ATP9A Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 9A (putative)
chr2_+_17753852 Show fit	17.86	ENST00000317402.11	GEN1 Ensembl NCBI GeneCards UniProt Show fit	GEN1 Holliday junction 5' flap endonuclease
chr13_-_36131286 Show fit	17.79	ENST00000255448.8 ENST00000379892.4	DCLK1 Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr2_-_86337617 Show fit	17.72	ENST00000538924.7 ENST00000535845.6	REEP1 Ensembl NCBI GeneCards UniProt Show fit	receptor accessory protein 1
chr20_+_46029165 Show fit	17.50	ENST00000616201.4 ENST00000616202.4 ENST00000616933.4 ENST00000626937.2	SLC12A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 5
chr16_+_6483813 Show fit	17.46	ENST00000675653.1	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr9_+_127611760 Show fit	17.35	ENST00000625363.2 ENST00000626539.3	STXBP1 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 1
chr9_+_128552558 Show fit	17.25	ENST00000372731.8 ENST00000630804.2 ENST00000372739.7 ENST00000627441.2 ENST00000358161.9 ENST00000636257.1	SPTAN1 Ensembl NCBI GeneCards UniProt Show fit	spectrin alpha, non-erythrocytic 1
chr8_+_141391989 Show fit	17.21	ENST00000520105.5 ENST00000523147.5 ENST00000521578.6	PTP4A3 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A3
chr6_-_46491956 Show fit	17.20	ENST00000306764.11	RCAN2 Ensembl NCBI GeneCards UniProt Show fit	regulator of calcineurin 2
chr22_+_39349925 Show fit	17.08	ENST00000318801.8 ENST00000216155.11 ENST00000406293.7 ENST00000328933.10	SYNGR1 Ensembl NCBI GeneCards UniProt Show fit	synaptogyrin 1
chr20_+_46029206 Show fit	17.03	ENST00000243964.7	SLC12A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 5
chr11_+_72080595 Show fit	17.02	ENST00000647530.1 ENST00000539271.6 ENST00000642510.1	LRTOMT Ensembl NCBI GeneCards UniProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing
chr1_-_31764333 Show fit	16.94	ENST00000398542.5 ENST00000373658.8	ADGRB2 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor B2
chr2_-_86337654 Show fit	16.91	ENST00000165698.9	REEP1 Ensembl NCBI GeneCards UniProt Show fit	receptor accessory protein 1
chr19_-_7874361 Show fit	16.72	ENST00000618550.5	PRR36 Ensembl NCBI GeneCards UniProt Show fit	proline rich 36
chr1_+_2050387 Show fit	16.64	ENST00000378567.8	PRKCZ Ensembl NCBI GeneCards UniProt Show fit	protein kinase C zeta
chr6_-_46491431 Show fit	16.52	ENST00000371374.6	RCAN2 Ensembl NCBI GeneCards UniProt Show fit	regulator of calcineurin 2
chr14_-_91060578 Show fit	16.28	ENST00000418736.6 ENST00000614987.5	RPS6KA5 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A5
chr11_-_64643315 Show fit	15.85	ENST00000301894.6	NRXN2 Ensembl NCBI GeneCards UniProt Show fit	neurexin 2
chr7_-_44325617 Show fit	15.85	ENST00000358707.7 ENST00000457475.5	CAMK2B Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II beta
chr14_+_61812673 Show fit	15.82	ENST00000683842.1 ENST00000636133.1	SYT16 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin 16
chr22_-_31346317 Show fit	15.72	ENST00000266269.10	PATZ1 Ensembl NCBI GeneCards UniProt Show fit	POZ/BTB and AT hook containing zinc finger 1
chr15_+_74995520 Show fit	15.53	ENST00000562327.5 ENST00000568018.5 ENST00000425597.8 ENST00000562212.5 ENST00000567920.5 ENST00000566872.5 ENST00000361900.10	SCAMP5 Ensembl NCBI GeneCards UniProt Show fit	secretory carrier membrane protein 5
chr4_-_101347327 Show fit	15.53	ENST00000394853.8	PPP3CA Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr14_-_100568475 Show fit	15.47	ENST00000553553.6	BEGAIN Ensembl NCBI GeneCards UniProt Show fit	brain enriched guanylate kinase associated
chr17_+_42659264 Show fit	15.41	ENST00000251412.8	TUBG2 Ensembl NCBI GeneCards UniProt Show fit	tubulin gamma 2
chr17_+_75047205 Show fit	15.38	ENST00000322444.7	KCTD2 Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 2
chr10_+_122461545 Show fit	15.37	ENST00000368984.8	HTRA1 Ensembl NCBI GeneCards UniProt Show fit	HtrA serine peptidase 1
chr5_+_77210881 Show fit	15.36	ENST00000340978.7 ENST00000346042.7 ENST00000342343.8 ENST00000333194.8	PDE8B Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 8B
chr19_+_35143237 Show fit	15.33	ENST00000586063.5 ENST00000270310.7 ENST00000588265.1	FXYD7 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 7
chr22_+_41381923 Show fit	15.24	ENST00000266304.9	TEF Ensembl NCBI GeneCards UniProt Show fit	TEF transcription factor, PAR bZIP family member
chr3_+_127629161 Show fit	15.23	ENST00000342480.7	PODXL2 Ensembl NCBI GeneCards UniProt Show fit	podocalyxin like 2
chr5_-_11904417 Show fit	15.18	ENST00000304623.13	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr17_-_80476597 Show fit	14.97	ENST00000306773.5	NPTX1 Ensembl NCBI GeneCards UniProt Show fit	neuronal pentraxin 1
chr19_+_35030438 Show fit	14.93	ENST00000415950.5 ENST00000262631.11	SCN1B Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel beta subunit 1
chr16_+_30699155 Show fit	14.85	ENST00000262518.9	SRCAP Ensembl NCBI GeneCards UniProt Show fit	Snf2 related CREBBP activator protein
chr14_-_93184840 Show fit	14.79	ENST00000298894.5 ENST00000556883.1	MOAP1 Ensembl NCBI GeneCards UniProt Show fit	modulator of apoptosis 1
chr7_+_121873317 Show fit	14.75	ENST00000651863.1 ENST00000652298.1 ENST00000449182.1	PTPRZ1 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type Z1
chr7_-_44325577 Show fit	14.72	ENST00000395749.7	CAMK2B Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II beta
chr3_+_49554436 Show fit	14.63	ENST00000296452.5	BSN Ensembl NCBI GeneCards UniProt Show fit	bassoon presynaptic cytomatrix protein
chr19_+_708903 Show fit	14.62	ENST00000338448.10 ENST00000264560.11	PALM Ensembl NCBI GeneCards UniProt Show fit	paralemmin
chr19_-_46471484 Show fit	14.59	ENST00000313683.15 ENST00000602246.1	PNMA8A Ensembl NCBI GeneCards UniProt Show fit	PNMA family member 8A
chr3_+_147409357 Show fit	14.34	ENST00000282928.5	ZIC1 Ensembl NCBI GeneCards UniProt Show fit	Zic family member 1
chr9_+_6757633 Show fit	14.27	ENST00000401787.7 ENST00000381306.7	KDM4C Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 4C
chr7_-_158829499 Show fit	14.18	ENST00000275418.13	ESYT2 Ensembl NCBI GeneCards UniProt Show fit	extended synaptotagmin 2
chr6_+_163414637 Show fit	14.16	ENST00000453779.6 ENST00000275262.11 ENST00000392127.6	QKI Ensembl NCBI GeneCards UniProt Show fit	QKI, KH domain containing RNA binding
chr19_-_18896081 Show fit	14.15	ENST00000429504.6 ENST00000623882.4 ENST00000247005.8	CERS1 Ensembl NCBI GeneCards UniProt Show fit GDF1 Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 1 growth differentiation factor 1
chr3_+_50674896 Show fit	14.12	ENST00000266037.10	DOCK3 Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 3
chr9_+_127612257 Show fit	13.94	ENST00000637173.2 ENST00000630492.2 ENST00000627871.2 ENST00000373302.8 ENST00000373299.5 ENST00000650920.1 ENST00000476182.3	STXBP1 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 1
chr4_-_5893075 Show fit	13.92	ENST00000324989.12	CRMP1 Ensembl NCBI GeneCards UniProt Show fit	collapsin response mediator protein 1
chrX_-_154097668 Show fit	13.86	ENST00000407218.5 ENST00000303391.11 ENST00000453960.7	MECP2 Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding protein 2
chr19_-_46471407 Show fit	13.80	ENST00000438932.2	PNMA8A Ensembl NCBI GeneCards UniProt Show fit	PNMA family member 8A
chr17_-_38799442 Show fit	13.75	ENST00000619039.5	PIP4K2B Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-5-phosphate 4-kinase type 2 beta
chr6_-_142945160 Show fit	13.41	ENST00000367603.8	HIVEP2 Ensembl NCBI GeneCards UniProt Show fit	HIVEP zinc finger 2
chr9_+_127612222 Show fit	13.08	ENST00000637953.1 ENST00000636962.2	STXBP1 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 1
chr4_+_41256921 Show fit	13.06	ENST00000284440.9 ENST00000508768.5 ENST00000512788.1	UCHL1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin C-terminal hydrolase L1
chr6_-_142945028 Show fit	12.98	ENST00000012134.7	HIVEP2 Ensembl NCBI GeneCards UniProt Show fit	HIVEP zinc finger 2
chr17_-_5500997 Show fit	12.90	ENST00000568641.2	ENSG00000286190.2 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr7_+_98617275 Show fit	12.90	ENST00000265634.4	NPTX2 Ensembl NCBI GeneCards UniProt Show fit	neuronal pentraxin 2
chr20_-_23637933 Show fit	12.89	ENST00000398411.5	CST3 Ensembl NCBI GeneCards UniProt Show fit	cystatin C
chr19_-_11481044 Show fit	12.85	ENST00000359227.8	ELAVL3 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 3
chr19_+_42313374 Show fit	12.85	ENST00000598766.1 ENST00000673187.1	TMEM145 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 145
chr11_+_114059755 Show fit	12.83	ENST00000684295.1	ZBTB16 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 16
chr17_-_37406757 Show fit	12.78	ENST00000616352.4	ACACA Ensembl NCBI GeneCards UniProt Show fit	acetyl-CoA carboxylase alpha
chr14_-_103847487 Show fit	12.74	ENST00000553739.2 ENST00000202556.14	PPP1R13B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 13B
chr2_+_130963642 Show fit	12.69	ENST00000409303.6	ARHGEF4 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 4
chr8_-_56446572 Show fit	12.69	ENST00000518974.5 ENST00000451791.7 ENST00000523051.5 ENST00000518770.1	PENK Ensembl NCBI GeneCards UniProt Show fit	proenkephalin
chr15_-_70854141 Show fit	12.65	ENST00000299213.10	LARP6 Ensembl NCBI GeneCards UniProt Show fit	La ribonucleoprotein 6, translational regulator
chr8_+_84183534 Show fit	12.62	ENST00000518566.5	RALYL Ensembl NCBI GeneCards UniProt Show fit	RALY RNA binding protein like
chrX_+_21374608 Show fit	12.62	ENST00000644295.1 ENST00000645074.1 ENST00000645791.1 ENST00000643220.1	CNKSR2 Ensembl NCBI GeneCards UniProt Show fit	connector enhancer of kinase suppressor of Ras 2
chr2_+_206443496 Show fit	12.61	ENST00000264377.8	ADAM23 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 23
chr11_+_72080313 Show fit	12.53	ENST00000307198.11 ENST00000538413.6 ENST00000642648.1 ENST00000289488.7	ENSG00000284922.2 Ensembl NCBI GeneCards UniProt Show fit LRTOMT Ensembl NCBI GeneCards UniProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing leucine rich transmembrane and O-methyltransferase domain containing
chr1_-_223364059 Show fit	12.49	ENST00000343846.7 ENST00000484758.6 ENST00000344029.6 ENST00000366878.9 ENST00000494793.6 ENST00000681285.1 ENST00000680429.1 ENST00000681669.1 ENST00000681305.1	SUSD4 Ensembl NCBI GeneCards UniProt Show fit	sushi domain containing 4
chr5_-_88883147 Show fit	12.44	ENST00000513252.5 ENST00000506554.5 ENST00000508569.5 ENST00000637732.1 ENST00000504921.7 ENST00000637481.1 ENST00000510942.5	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr7_-_158829519 Show fit	12.43	ENST00000251527.10 ENST00000652148.1	ESYT2 Ensembl NCBI GeneCards UniProt Show fit	extended synaptotagmin 2
chr11_-_1572261 Show fit	12.42	ENST00000397374.8	DUSP8 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 8
chr6_-_33317728 Show fit	12.41	ENST00000431845.3	ZBTB22 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 22
chr7_+_69598292 Show fit	12.39	ENST00000644939.1	AUTS2 Ensembl NCBI GeneCards UniProt Show fit	activator of transcription and developmental regulator AUTS2
chr15_+_72118392 Show fit	12.31	ENST00000340912.6	SENP8 Ensembl NCBI GeneCards UniProt Show fit	SUMO peptidase family member, NEDD8 specific
chr8_+_42896883 Show fit	12.29	ENST00000307602.9	HOOK3 Ensembl NCBI GeneCards UniProt Show fit	hook microtubule tethering protein 3
chr19_-_54189670 Show fit	12.26	ENST00000391754.5	MBOAT7 Ensembl NCBI GeneCards UniProt Show fit	membrane bound O-acyltransferase domain containing 7
chr11_+_114060204 Show fit	12.16	ENST00000683318.1	ZBTB16 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 16
chr8_+_84183262 Show fit	12.09	ENST00000522455.5 ENST00000521695.5 ENST00000521268.6	RALYL Ensembl NCBI GeneCards UniProt Show fit	RALY RNA binding protein like
chr1_+_210328894 Show fit	11.99	ENST00000261458.8 ENST00000537898.5 ENST00000545154.5	HHAT Ensembl NCBI GeneCards UniProt Show fit	hedgehog acyltransferase
chr12_+_51951663 Show fit	11.95	ENST00000257963.9 ENST00000541224.5 ENST00000426655.6 ENST00000536420.5 ENST00000415850.6	ACVR1B Ensembl NCBI GeneCards UniProt Show fit	activin A receptor type 1B
chr10_-_931624 Show fit	11.95	ENST00000406525.6	LARP4B Ensembl NCBI GeneCards UniProt Show fit	La ribonucleoprotein 4B
chr17_-_81166160 Show fit	11.94	ENST00000326724.9	AATK Ensembl NCBI GeneCards UniProt Show fit	apoptosis associated tyrosine kinase
chr5_+_77210667 Show fit	11.91	ENST00000264917.10	PDE8B Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 8B
chr11_+_114059702 Show fit	11.91	ENST00000335953.9 ENST00000684612.1 ENST00000682810.1 ENST00000544220.1	ZBTB16 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 16
chr20_+_20368096 Show fit	11.87	ENST00000310227.3	INSM1 Ensembl NCBI GeneCards UniProt Show fit	INSM transcriptional repressor 1
chr19_+_47778585 Show fit	11.76	ENST00000509570.6 ENST00000612212.4 ENST00000593892.5	SELENOW Ensembl NCBI GeneCards UniProt Show fit	selenoprotein W
chr5_-_88883701 Show fit	11.71	ENST00000636998.1	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr13_-_36131352 Show fit	11.70	ENST00000360631.8	DCLK1 Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr4_-_101347492 Show fit	11.66	ENST00000394854.8	PPP3CA Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chr17_+_55266216 Show fit	11.64	ENST00000573945.5	HLF Ensembl NCBI GeneCards UniProt Show fit	HLF transcription factor, PAR bZIP family member
chr6_-_166627244 Show fit	11.56	ENST00000265678.9	RPS6KA2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A2
chr20_+_58889168 Show fit	11.56	ENST00000480975.5 ENST00000480232.6 ENST00000484504.5	GNAS Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr19_+_46860972 Show fit	11.43	ENST00000672722.1	ARHGAP35 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 35
chr1_+_84078043 Show fit	11.41	ENST00000370689.6 ENST00000370688.7	PRKACB Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-activated catalytic subunit beta
chr9_-_112333603 Show fit	11.38	ENST00000450374.1 ENST00000374257.6 ENST00000374255.6 ENST00000334318.10	PTBP3 Ensembl NCBI GeneCards UniProt Show fit	polypyrimidine tract binding protein 3
chr16_+_1612337 Show fit	11.29	ENST00000674071.1 ENST00000397412.8	CRAMP1 Ensembl NCBI GeneCards UniProt Show fit	cramped chromatin regulator homolog 1
chr11_-_61917490 Show fit	11.18	ENST00000394836.7	RAB3IL1 Ensembl NCBI GeneCards UniProt Show fit	RAB3A interacting protein like 1
chr7_+_65873242 Show fit	11.14	ENST00000648179.1	VKORC1L1 Ensembl NCBI GeneCards UniProt Show fit	vitamin K epoxide reductase complex subunit 1 like 1
chr19_+_47778689 Show fit	11.14	ENST00000595615.1 ENST00000601048.6	SELENOW Ensembl NCBI GeneCards UniProt Show fit	selenoprotein W
chr20_-_23637947 Show fit	11.13	ENST00000376925.8	CST3 Ensembl NCBI GeneCards UniProt Show fit	cystatin C
chr19_+_4969105 Show fit	11.12	ENST00000611640.4 ENST00000159111.9 ENST00000588337.5 ENST00000381759.8	KDM4B Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 4B
chr12_-_121296685 Show fit	10.99	ENST00000412367.6 ENST00000404169.8 ENST00000402834.8	CAMKK2 Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase kinase 2
chr2_-_219229309 Show fit	10.98	ENST00000443140.5 ENST00000432520.5 ENST00000409618.5	ATG9A Ensembl NCBI GeneCards UniProt Show fit	autophagy related 9A
chr12_-_121296669 Show fit	10.95	ENST00000652382.1	CAMKK2 Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase kinase 2
chr9_+_34958254 Show fit	10.94	ENST00000242315.3	PHF24 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 24
chr17_+_38351832 Show fit	10.86	ENST00000612932.6	SOCS7 Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 7
chr11_+_17719564 Show fit	10.84	ENST00000250003.4	MYOD1 Ensembl NCBI GeneCards UniProt Show fit	myogenic differentiation 1
chr6_-_6007511 Show fit	10.82	ENST00000616243.1	NRN1 Ensembl NCBI GeneCards UniProt Show fit	neuritin 1
chr9_-_13279407 Show fit	10.79	ENST00000546205.5	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain crumbs cell polarity complex component
chr20_+_58891704 Show fit	10.74	ENST00000371081.5 ENST00000338783.7	GNAS Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr13_+_26557659 Show fit	10.72	ENST00000335327.6 ENST00000361042.8 ENST00000671038.1	WASF3 Ensembl NCBI GeneCards UniProt Show fit	WASP family member 3
chrX_+_136147465 Show fit	10.65	ENST00000651929.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr4_-_101347471 Show fit	10.64	ENST00000323055.10 ENST00000512215.5	PPP3CA Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3 catalytic subunit alpha
chrX_-_138711663 Show fit	10.63	ENST00000315930.11	FGF13 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor 13
chr9_-_13279642 Show fit	10.60	ENST00000319217.12	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain crumbs cell polarity complex component
chr10_-_689613 Show fit	10.52	ENST00000280886.12 ENST00000634311.1	DIP2C Ensembl NCBI GeneCards UniProt Show fit	disco interacting protein 2 homolog C
chr5_-_178627001 Show fit	10.46	ENST00000611575.4 ENST00000520957.1 ENST00000316308.9 ENST00000611733.4	CLK4 Ensembl NCBI GeneCards UniProt Show fit	CDC like kinase 4
chr7_+_156949704 Show fit	10.34	ENST00000275820.4	NOM1 Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein with MIF4G domain 1
chr19_-_461007 Show fit	10.32	ENST00000264554.11	SHC2 Ensembl NCBI GeneCards UniProt Show fit	SHC adaptor protein 2
chr8_+_28701487 Show fit	10.28	ENST00000220562.9	EXTL3 Ensembl NCBI GeneCards UniProt Show fit	exostosin like glycosyltransferase 3
chr10_+_47300174 Show fit	10.27	ENST00000580279.2	GDF10 Ensembl NCBI GeneCards UniProt Show fit	growth differentiation factor 10
chr1_+_1435523 Show fit	10.22	ENST00000338660.5 ENST00000476993.2 ENST00000471398.1	VWA1 Ensembl NCBI GeneCards UniProt Show fit	von Willebrand factor A domain containing 1
chr2_+_206443830 Show fit	10.19	ENST00000374415.7	ADAM23 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 23
chrX_+_21374434 Show fit	10.15	ENST00000279451.9 ENST00000645245.1	CNKSR2 Ensembl NCBI GeneCards UniProt Show fit	connector enhancer of kinase suppressor of Ras 2
chr16_-_1611985 Show fit	10.15	ENST00000426508.7	IFT140 Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 140
chr2_-_99141414 Show fit	10.13	ENST00000393482.7	TSGA10 Ensembl NCBI GeneCards UniProt Show fit	testis specific 10
chr8_-_144462848 Show fit	10.12	ENST00000530374.6	CYHR1 Ensembl NCBI GeneCards UniProt Show fit	cysteine and histidine rich 1
chrX_+_21374288 Show fit	10.09	ENST00000642359.1	CNKSR2 Ensembl NCBI GeneCards UniProt Show fit	connector enhancer of kinase suppressor of Ras 2
chr20_-_36863517 Show fit	10.04	ENST00000237536.9	SOGA1 Ensembl NCBI GeneCards UniProt Show fit	suppressor of glucose, autophagy associated 1
chr9_-_13279564 Show fit	10.03	ENST00000541718.5 ENST00000447879.6	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain crumbs cell polarity complex component
chr7_+_65873091 Show fit	9.97	ENST00000648187.1	VKORC1L1 Ensembl NCBI GeneCards UniProt Show fit	vitamin K epoxide reductase complex subunit 1 like 1
chr16_-_5033587 Show fit	9.97	ENST00000563578.5 ENST00000562346.2	NAGPA Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr19_+_35138778 Show fit	9.93	ENST00000351325.9 ENST00000586871.5 ENST00000592174.1	FXYD1 Ensembl NCBI GeneCards UniProt Show fit ENSG00000221857.7 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 1 novel transcript
chr2_+_99141696 Show fit	9.92	ENST00000650052.2 ENST00000409684.2	C2orf15 Ensembl NCBI GeneCards UniProt Show fit	chromosome 2 open reading frame 15
chr3_-_149971109 Show fit	9.87	ENST00000239940.11	PFN2 Ensembl NCBI GeneCards UniProt Show fit	profilin 2
chr9_-_83956677 Show fit	9.75	ENST00000376344.8	C9orf64 Ensembl NCBI GeneCards UniProt Show fit	chromosome 9 open reading frame 64
chr9_+_137139481 Show fit	9.71	ENST00000371546.8 ENST00000371550.8 ENST00000371553.7 ENST00000371555.8 ENST00000371559.8 ENST00000371560.4	GRIN1 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor NMDA type subunit 1
chr16_-_5033916 Show fit	9.71	ENST00000381955.7 ENST00000312251.8	NAGPA Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr17_+_12789457 Show fit	9.70	ENST00000379672.10 ENST00000340825.7	ARHGAP44 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 44
chrX_-_8732116 Show fit	9.56	ENST00000262648.8	ANOS1 Ensembl NCBI GeneCards UniProt Show fit	anosmin 1
chr2_+_24491239 Show fit	9.56	ENST00000348332.8	NCOA1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor coactivator 1
chrX_+_136147525 Show fit	9.55	ENST00000652745.1 ENST00000627578.2 ENST00000652457.1 ENST00000394155.8 ENST00000618438.4	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chrX_+_21374357 Show fit	9.39	ENST00000643841.1 ENST00000379510.5 ENST00000425654.7 ENST00000644798.1 ENST00000543067.6	CNKSR2 Ensembl NCBI GeneCards UniProt Show fit	connector enhancer of kinase suppressor of Ras 2
chr5_-_137499293 Show fit	9.33	ENST00000510689.5 ENST00000394945.6	SPOCK1 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
chr22_-_38844020 Show fit	9.30	ENST00000333039.4	NPTXR Ensembl NCBI GeneCards UniProt Show fit	neuronal pentraxin receptor
chr9_-_75088198 Show fit	9.27	ENST00000376808.8	NMRK1 Ensembl NCBI GeneCards UniProt Show fit	nicotinamide riboside kinase 1
chr1_-_241357171 Show fit	9.26	ENST00000440928.6	RGS7 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.5	49.4	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
11.5	57.4	GO:0007412	axon target recognition(GO:0007412)
10.9	43.6	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
10.6	53.2	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
10.6	31.9	GO:2000374	negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
7.6	30.5	GO:0033693	neurofilament bundle assembly(GO:0033693)
6.9	138.6	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
6.8	20.5	GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
6.5	19.6	GO:0044805	late nucleophagy(GO:0044805)
6.4	19.3	GO:0098582	innate vocalization behavior(GO:0098582)
6.1	36.9	GO:0051138	positive regulation of NK T cell differentiation(GO:0051138)
6.0	17.9	GO:0071139	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
5.8	34.5	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
5.5	16.6	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
5.2	51.7	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
5.1	25.4	GO:1904209	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
4.9	14.8	GO:0043449	olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
4.9	14.6	GO:0099526	presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
4.9	24.3	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
4.7	14.2	GO:0036146	cellular response to mycotoxin(GO:0036146)
4.4	22.2	GO:0030070	insulin processing(GO:0030070)
4.3	12.9	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
4.3	12.8	GO:0032888	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
4.0	24.0	GO:0060313	negative regulation of blood vessel remodeling(GO:0060313)
4.0	63.6	GO:0070445	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
4.0	31.6	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
4.0	11.9	GO:0003358	noradrenergic neuron development(GO:0003358)
3.8	11.4	GO:1904017	cellular response to Thyroglobulin triiodothyronine(GO:1904017)
3.7	11.0	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
3.6	14.5	GO:1904800	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
3.6	10.8	GO:0007518	myoblast fate determination(GO:0007518)
3.5	42.6	GO:0016191	synaptic vesicle uncoating(GO:0016191)
3.5	46.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
3.3	16.6	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
3.3	29.9	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
3.2	12.8	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
3.2	12.7	GO:0051866	general adaptation syndrome(GO:0051866)
3.1	15.4	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
3.1	18.4	GO:0021966	corticospinal neuron axon guidance(GO:0021966)
3.0	9.1	GO:0072674	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
3.0	15.0	GO:0060385	axonogenesis involved in innervation(GO:0060385)
2.9	11.8	GO:0071110	protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
2.9	14.6	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
2.7	8.2	GO:0016340	calcium-dependent cell-matrix adhesion(GO:0016340)
2.7	52.0	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
2.7	8.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
2.7	10.6	GO:1990834	response to odorant(GO:1990834)
2.6	52.4	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
2.5	2.5	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
2.5	9.8	GO:0060024	rhythmic synaptic transmission(GO:0060024)
2.4	7.2	GO:0009386	translational attenuation(GO:0009386)
2.4	21.7	GO:0098535	de novo centriole assembly(GO:0098535)
2.3	11.7	GO:1990164	histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
2.3	11.4	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
2.3	18.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
2.3	36.0	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
2.2	6.5	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
2.1	8.6	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
2.1	6.3	GO:1904616	regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
2.1	23.0	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
2.1	10.3	GO:0071494	cellular response to UV-C(GO:0071494)
2.1	12.3	GO:0016926	protein desumoylation(GO:0016926)
2.1	6.2	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
2.0	12.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
2.0	76.3	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
1.9	27.0	GO:0070544	histone H3-K36 demethylation(GO:0070544)
1.9	9.6	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
1.9	5.7	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
1.9	11.4	GO:0097338	response to clozapine(GO:0097338)
1.9	9.3	GO:0051510	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
1.8	5.5	GO:1900239	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.8	5.5	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
1.8	14.4	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
1.8	19.7	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
1.8	16.0	GO:1902527	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) positive regulation of protein monoubiquitination(GO:1902527)
1.8	21.1	GO:0042373	vitamin K metabolic process(GO:0042373)
1.8	14.0	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
1.7	19.1	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
1.7	20.3	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
1.7	5.1	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
1.7	9.9	GO:0010734	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
1.6	4.9	GO:0098935	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
1.6	11.4	GO:0090170	regulation of Golgi inheritance(GO:0090170)
1.6	8.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
1.6	8.0	GO:0014886	transition between slow and fast fiber(GO:0014886)
1.5	4.6	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
1.5	4.6	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
1.5	25.8	GO:0015671	oxygen transport(GO:0015671)
1.5	4.5	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
1.5	9.0	GO:0031584	activation of phospholipase D activity(GO:0031584)
1.5	5.9	GO:0030035	microspike assembly(GO:0030035)
1.5	5.8	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.4	4.3	GO:0051230	mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
1.4	15.9	GO:0097106	postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.4	17.0	GO:0043249	erythrocyte maturation(GO:0043249)
1.4	4.2	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
1.3	7.9	GO:0042780	tRNA 3'-end processing(GO:0042780)
1.3	7.9	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
1.3	17.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.3	9.1	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
1.3	2.6	GO:0050915	sensory perception of sour taste(GO:0050915)
1.3	7.5	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
1.3	8.8	GO:1901563	cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563)
1.3	10.0	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.2	6.2	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
1.2	3.7	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
1.2	7.4	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
1.2	2.4	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
1.2	22.8	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
1.2	7.1	GO:1905247	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
1.2	3.5	GO:0072233	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
1.2	6.9	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.1	6.9	GO:0007042	lysosomal lumen acidification(GO:0007042)
1.1	3.4	GO:0002086	diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011)
1.1	87.5	GO:0051965	positive regulation of synapse assembly(GO:0051965)
1.1	7.9	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
1.1	10.2	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
1.1	5.6	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
1.1	4.4	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
1.1	6.5	GO:0035617	stress granule disassembly(GO:0035617)
1.1	50.3	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
1.1	4.2	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
1.1	34.0	GO:0008045	motor neuron axon guidance(GO:0008045)
1.1	6.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
1.0	6.2	GO:0048549	positive regulation of pinocytosis(GO:0048549)
1.0	1.0	GO:0009450	gamma-aminobutyric acid catabolic process(GO:0009450)
1.0	6.9	GO:0045176	apical protein localization(GO:0045176)
1.0	54.7	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
1.0	4.9	GO:0071233	cellular response to leucine(GO:0071233)
1.0	21.3	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
1.0	2.9	GO:0000103	sulfate assimilation(GO:0000103)
1.0	2.9	GO:0070625	zymogen granule exocytosis(GO:0070625)
0.9	4.7	GO:1904693	midbrain morphogenesis(GO:1904693)
0.9	2.8	GO:0009397	folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.9	4.5	GO:0075071	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.9	0.9	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.9	2.7	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.9	5.3	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.9	1.8	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621)
0.9	3.5	GO:2000672	regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.9	7.9	GO:0072344	rescue of stalled ribosome(GO:0072344)
0.9	8.7	GO:0032594	protein transport within lipid bilayer(GO:0032594)
0.9	5.2	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.9	6.0	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.8	43.2	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.8	5.1	GO:1904978	regulation of endosome organization(GO:1904978)
0.8	7.6	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.8	6.7	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.8	5.0	GO:0035897	proteolysis in other organism(GO:0035897)
0.8	13.4	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.8	13.2	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.8	11.5	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.8	4.1	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.8	6.4	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.8	1.6	GO:0003064	regulation of heart rate by hormone(GO:0003064)
0.8	3.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.8	3.1	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.8	16.5	GO:0048266	behavioral response to pain(GO:0048266)
0.8	10.0	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.8	5.4	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.8	11.5	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.8	2.3	GO:0097534	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.8	5.3	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.8	6.1	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.8	6.8	GO:0032482	Rab protein signal transduction(GO:0032482)
0.8	22.0	GO:0097503	sialylation(GO:0097503)
0.8	3.8	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
0.7	15.0	GO:0097186	amelogenesis(GO:0097186)
0.7	2.2	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.7	3.7	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.7	26.3	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.7	5.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.7	17.9	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.7	4.2	GO:0032252	secretory granule localization(GO:0032252)
0.7	9.2	GO:0035330	regulation of hippo signaling(GO:0035330)
0.7	4.1	GO:0035063	nuclear speck organization(GO:0035063)
0.7	23.3	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.7	4.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.7	31.2	GO:0021762	substantia nigra development(GO:0021762)
0.7	11.3	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.7	10.4	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.7	5.2	GO:0060591	chondroblast differentiation(GO:0060591)
0.6	3.2	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.6	5.1	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.6	15.0	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.6	3.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.6	12.0	GO:0018345	protein palmitoylation(GO:0018345)
0.6	9.0	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.6	10.7	GO:0006012	galactose metabolic process(GO:0006012)
0.6	10.7	GO:0031643	positive regulation of myelination(GO:0031643)
0.6	10.2	GO:0050812	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.6	27.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.6	15.9	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.6	2.8	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.6	3.9	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.6	2.3	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.6	3.9	GO:0061734	ubiquitin-dependent SMAD protein catabolic process(GO:0030579) parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.6	2.2	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.6	17.6	GO:0009435	NAD biosynthetic process(GO:0009435)
0.6	5.0	GO:0045475	locomotor rhythm(GO:0045475)
0.5	26.6	GO:0045773	positive regulation of axon extension(GO:0045773)
0.5	0.5	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.5	2.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.5	5.0	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.5	5.0	GO:0015824	proline transport(GO:0015824)
0.5	2.0	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.5	1.9	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.5	4.2	GO:0050713	positive regulation of MHC class I biosynthetic process(GO:0045345) negative regulation of interleukin-1 beta secretion(GO:0050713)
0.5	2.8	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.5	5.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.5	6.5	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.5	1.8	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.5	3.2	GO:1903358	regulation of Golgi organization(GO:1903358)
0.5	2.7	GO:2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.5	19.4	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4	5.4	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.4	3.1	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.4	0.9	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.4	7.1	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.4	3.1	GO:0080009	mRNA methylation(GO:0080009)
0.4	7.8	GO:0001767	establishment of lymphocyte polarity(GO:0001767)
0.4	4.3	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.4	29.0	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.4	4.6	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.4	7.5	GO:0006895	Golgi to endosome transport(GO:0006895)
0.4	10.7	GO:0008038	neuron recognition(GO:0008038)
0.4	5.4	GO:0007258	JUN phosphorylation(GO:0007258)
0.4	1.6	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4	4.8	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.4	15.6	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.4	4.3	GO:0060074	synapse maturation(GO:0060074)
0.4	8.2	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.4	6.2	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.4	7.7	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.4	2.7	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.4	4.5	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.4	16.4	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.4	21.8	GO:0046847	filopodium assembly(GO:0046847)
0.4	4.0	GO:1990403	embryonic brain development(GO:1990403)
0.4	2.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.4	5.1	GO:0036158	outer dynein arm assembly(GO:0036158)
0.4	3.2	GO:0015871	choline transport(GO:0015871)
0.4	21.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.4	3.9	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.4	3.2	GO:0033127	regulation of histone phosphorylation(GO:0033127)
0.3	1.0	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.3	3.3	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.3	2.6	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3	6.9	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.3	1.3	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378) vitamin D3 metabolic process(GO:0070640)
0.3	3.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.3	1.3	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
0.3	2.6	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3	2.2	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.3	1.6	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.3	5.3	GO:0032486	Rap protein signal transduction(GO:0032486)
0.3	2.5	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3	5.5	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.3	1.5	GO:0070092	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.3	4.7	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3	0.9	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.3	1.4	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.3	2.2	GO:0044804	nucleophagy(GO:0044804)
0.3	1.9	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3	12.1	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.3	2.7	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.3	4.2	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3	1.3	GO:0071895	odontoblast differentiation(GO:0071895)
0.3	7.4	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.3	2.6	GO:0072178	nephric duct morphogenesis(GO:0072178)
0.3	2.5	GO:0000733	DNA strand renaturation(GO:0000733)
0.2	1.0	GO:0000429	carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991)
0.2	4.0	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.2	3.7	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.2	3.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.2	5.2	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.2	2.7	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.2	1.7	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.2	2.5	GO:1901621	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2	5.1	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.2	0.7	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.2	6.0	GO:0035640	exploration behavior(GO:0035640)
0.2	3.1	GO:0099624	atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.2	7.4	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2	1.2	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2	21.3	GO:0001764	neuron migration(GO:0001764)
0.2	1.2	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2	7.7	GO:0006783	heme biosynthetic process(GO:0006783)
0.2	5.4	GO:0035411	catenin import into nucleus(GO:0035411)
0.2	8.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.2	1.8	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.2	1.6	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.2	0.9	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.2	6.1	GO:0030261	chromosome condensation(GO:0030261)
0.2	2.6	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.2	4.5	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.2	2.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.2	0.6	GO:0050893	sensory processing(GO:0050893)
0.2	27.6	GO:0006836	neurotransmitter transport(GO:0006836)
0.2	5.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2	10.8	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.2	0.8	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2	1.4	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.2	2.1	GO:0015074	DNA integration(GO:0015074)
0.2	8.7	GO:0033344	cholesterol efflux(GO:0033344)
0.2	8.3	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.2	4.9	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.2	1.7	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.2	1.5	GO:0032026	response to magnesium ion(GO:0032026)
0.2	0.9	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.2	5.1	GO:0021515	cell differentiation in spinal cord(GO:0021515)
0.2	11.4	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.2	2.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.2	9.8	GO:0006400	tRNA modification(GO:0006400)
0.2	4.1	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.2	4.1	GO:0007020	microtubule nucleation(GO:0007020)
0.2	22.5	GO:0008584	male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.2	13.7	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.2	4.2	GO:0015695	organic cation transport(GO:0015695)
0.2	3.2	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.2	4.6	GO:0010107	potassium ion import(GO:0010107)
0.2	3.1	GO:0007141	male meiosis I(GO:0007141)
0.2	0.6	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.2	6.7	GO:0010165	response to X-ray(GO:0010165)
0.1	13.8	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.1	1.9	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	5.7	GO:0001658	branching involved in ureteric bud morphogenesis(GO:0001658)
0.1	0.6	GO:0048861	oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.7	GO:0034350	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1	2.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.1	1.2	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1	1.4	GO:0001955	blood vessel maturation(GO:0001955)
0.1	1.8	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1	0.8	GO:0071105	response to interleukin-11(GO:0071105)
0.1	2.2	GO:0070932	histone H3 deacetylation(GO:0070932)
0.1	3.4	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.1	10.3	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.1	2.1	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.1	5.0	GO:0001578	microtubule bundle formation(GO:0001578)
0.1	3.6	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1	75.2	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.1	3.4	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.1	2.2	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.1	12.0	GO:0098869	cellular oxidant detoxification(GO:0098869)
0.1	2.2	GO:0036035	osteoclast development(GO:0036035)
0.1	0.5	GO:0001675	acrosome assembly(GO:0001675)
0.1	4.3	GO:0030593	neutrophil chemotaxis(GO:0030593)
0.1	7.6	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.1	1.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.1	12.0	GO:0030449	regulation of complement activation(GO:0030449)
0.1	4.4	GO:0034308	primary alcohol metabolic process(GO:0034308)
0.1	1.6	GO:0030516	regulation of axon extension(GO:0030516)
0.1	3.5	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.1	2.5	GO:0006040	amino sugar metabolic process(GO:0006040)
0.1	1.2	GO:0051382	kinetochore assembly(GO:0051382)
0.1	7.2	GO:0048515	spermatid differentiation(GO:0048515)
0.1	0.4	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.4	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.1	2.3	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.1	3.0	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	0.3	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	0.9	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.1	2.0	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.5	GO:0043586	tongue development(GO:0043586)
0.1	2.0	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.1	1.9	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.1	5.5	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	1.9	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.1	0.3	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.4	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0	0.8	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.5	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.0	0.3	GO:0009597	detection of virus(GO:0009597)
0.0	1.9	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	2.3	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	0.9	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.6	GO:0001502	cartilage condensation(GO:0001502)
0.0	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.4	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	1.0	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	1.8	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.2	GO:0001946	lymphangiogenesis(GO:0001946)
0.0	0.7	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
25.0	74.9	GO:0098843	postsynaptic endocytic zone(GO:0098843)
12.7	63.6	GO:0072534	perineuronal net(GO:0072534)
8.9	53.2	GO:0045298	tubulin complex(GO:0045298)
7.4	44.4	GO:0048787	presynaptic active zone membrane(GO:0048787)
7.2	36.0	GO:0097454	Schwann cell microvillus(GO:0097454)
6.5	25.8	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
6.5	58.1	GO:1990761	growth cone lamellipodium(GO:1990761)
4.9	14.6	GO:0048788	cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
4.3	12.8	GO:0055028	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
4.2	25.4	GO:0033269	internode region of axon(GO:0033269)
4.0	44.5	GO:0005955	calcineurin complex(GO:0005955)
4.0	31.9	GO:0097450	astrocyte end-foot(GO:0097450)
3.9	15.7	GO:0070695	FHF complex(GO:0070695)
3.0	48.6	GO:0005883	neurofilament(GO:0005883)
3.0	12.0	GO:0048179	activin receptor complex(GO:0048179)
2.9	32.4	GO:0043203	axon hillock(GO:0043203)
2.0	6.0	GO:0016938	kinesin I complex(GO:0016938)
1.9	27.1	GO:0043083	synaptic cleft(GO:0043083)
1.8	12.7	GO:0032280	symmetric synapse(GO:0032280)
1.7	103.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
1.6	34.6	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
1.6	140.2	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
1.5	23.8	GO:0030914	STAGA complex(GO:0030914)
1.5	13.2	GO:0000137	Golgi cis cisterna(GO:0000137)
1.5	14.6	GO:0005614	interstitial matrix(GO:0005614)
1.5	10.2	GO:0030991	intraciliary transport particle A(GO:0030991)
1.4	12.3	GO:0097427	microtubule bundle(GO:0097427)
1.3	19.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
1.3	91.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
1.2	6.2	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
1.2	7.4	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.2	24.1	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
1.2	3.5	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
1.1	17.2	GO:0008091	spectrin(GO:0008091)
1.1	11.9	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.0	6.2	GO:0072687	meiotic spindle(GO:0072687)
1.0	14.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
1.0	58.7	GO:0043198	dendritic shaft(GO:0043198)
1.0	11.6	GO:0042788	polysomal ribosome(GO:0042788)
0.9	4.7	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.9	20.7	GO:0000930	gamma-tubulin complex(GO:0000930)
0.9	5.4	GO:0097208	alveolar lamellar body(GO:0097208)
0.9	14.6	GO:0032591	dendritic spine membrane(GO:0032591)
0.8	30.3	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.8	4.9	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.8	3.1	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
0.8	8.5	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.8	6.0	GO:0072487	MSL complex(GO:0072487)
0.7	5.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.7	5.1	GO:0036157	outer dynein arm(GO:0036157)
0.7	2.8	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.7	4.9	GO:0035253	ciliary rootlet(GO:0035253)
0.7	7.0	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.7	2.1	GO:0071942	XPC complex(GO:0071942)
0.7	6.9	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.6	7.8	GO:0071203	WASH complex(GO:0071203)
0.6	4.5	GO:0044530	supraspliceosomal complex(GO:0044530)
0.6	3.2	GO:0001939	female pronucleus(GO:0001939)
0.6	3.7	GO:0032009	early phagosome(GO:0032009)
0.6	3.1	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.6	4.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.6	14.9	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.6	5.4	GO:0044294	dendritic growth cone(GO:0044294)
0.6	7.6	GO:0031045	dense core granule(GO:0031045)
0.6	73.7	GO:0005814	centriole(GO:0005814)
0.6	9.9	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5	10.7	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5	1.6	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.5	1.6	GO:0000125	PCAF complex(GO:0000125)
0.5	12.3	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.5	17.3	GO:0048786	presynaptic active zone(GO:0048786)
0.5	10.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.5	14.8	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.5	29.8	GO:0043195	terminal bouton(GO:0043195)
0.5	10.0	GO:0005652	nuclear lamina(GO:0005652)
0.4	30.9	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.4	129.9	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.4	90.5	GO:0005802	trans-Golgi network(GO:0005802)
0.4	5.3	GO:0097440	apical dendrite(GO:0097440)
0.4	2.3	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4	36.9	GO:0043204	perikaryon(GO:0043204)
0.4	21.7	GO:0044306	neuron projection terminus(GO:0044306)
0.4	8.7	GO:0031143	pseudopodium(GO:0031143)
0.4	14.5	GO:0016235	aggresome(GO:0016235)
0.4	21.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4	3.9	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.3	17.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.3	9.8	GO:0031527	filopodium membrane(GO:0031527)
0.3	3.7	GO:0060076	excitatory synapse(GO:0060076)
0.3	4.3	GO:0000815	ESCRT III complex(GO:0000815)
0.3	5.8	GO:0005922	connexon complex(GO:0005922)
0.3	2.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.3	24.0	GO:1904724	tertiary granule lumen(GO:1904724)
0.3	5.6	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.3	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.3	2.0	GO:0000124	SAGA complex(GO:0000124)
0.3	15.2	GO:0005776	autophagosome(GO:0005776)
0.2	30.4	GO:0030426	growth cone(GO:0030426)
0.2	2.5	GO:0016461	unconventional myosin complex(GO:0016461)
0.2	2.3	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.2	9.6	GO:0009925	basal plasma membrane(GO:0009925)
0.2	15.4	GO:0055037	recycling endosome(GO:0055037)
0.2	5.4	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.2	27.3	GO:0098793	presynapse(GO:0098793)
0.2	4.6	GO:0005721	pericentric heterochromatin(GO:0005721)
0.2	1.0	GO:0032449	CBM complex(GO:0032449)
0.2	7.3	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.2	4.2	GO:0042629	mast cell granule(GO:0042629)
0.2	18.6	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2	5.0	GO:0005680	anaphase-promoting complex(GO:0005680)
0.2	2.9	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.2	2.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.2	6.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.2	15.1	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1	1.6	GO:0001741	XY body(GO:0001741)
0.1	0.3	GO:0030137	COPI-coated vesicle(GO:0030137)
0.1	1.7	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	4.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	1.3	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	1.5	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	10.8	GO:0043202	lysosomal lumen(GO:0043202)
0.1	6.4	GO:0031672	A band(GO:0031672)
0.1	5.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	1.3	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.1	16.4	GO:0031225	anchored component of membrane(GO:0031225)
0.1	5.1	GO:0036064	ciliary basal body(GO:0036064)
0.1	0.8	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	1.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	2.4	GO:0016328	lateral plasma membrane(GO:0016328)
0.1	4.9	GO:0060170	ciliary membrane(GO:0060170)
0.1	1.9	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.1	1.8	GO:0016580	Sin3 complex(GO:0016580)
0.1	2.5	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	3.6	GO:0001533	cornified envelope(GO:0001533)
0.1	7.4	GO:0045177	apical part of cell(GO:0045177)
0.1	9.6	GO:0045211	postsynaptic membrane(GO:0045211)
0.1	5.5	GO:0019898	extrinsic component of membrane(GO:0019898)
0.1	1.8	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	1.0	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	2.1	GO:0005871	kinesin complex(GO:0005871)
0.0	3.8	GO:0005923	bicellular tight junction(GO:0005923)
0.0	23.1	GO:0000139	Golgi membrane(GO:0000139)
0.0	14.2	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	0.5	GO:0030666	endocytic vesicle membrane(GO:0030666)
0.0	1.8	GO:0005884	actin filament(GO:0005884)
0.0	0.6	GO:0030286	dynein complex(GO:0030286)
0.0	1.2	GO:0098794	postsynapse(GO:0098794)
0.0	1.2	GO:0001726	ruffle(GO:0001726)
0.0	47.9	GO:0016021	integral component of membrane(GO:0016021)
0.0	0.8	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	1.2	GO:0030027	lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.3	53.2	GO:0099609	microtubule lateral binding(GO:0099609)
11.5	34.6	GO:0031849	olfactory receptor binding(GO:0031849)
9.4	74.9	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
6.9	20.6	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
5.3	47.9	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
4.7	42.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
4.6	13.7	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
4.5	22.6	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
4.4	17.6	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
4.1	24.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
3.8	11.4	GO:0033142	progesterone receptor binding(GO:0033142)
3.6	10.7	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
3.5	21.1	GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
3.0	14.9	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
2.9	11.8	GO:0004078	biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
2.7	134.1	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
2.7	31.9	GO:0046870	cadmium ion binding(GO:0046870)
2.6	62.4	GO:0051429	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
2.6	36.3	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.6	10.2	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.6	17.9	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
2.5	7.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
2.5	14.8	GO:1904315	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
2.3	20.4	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
2.2	11.0	GO:0043546	molybdopterin cofactor binding(GO:0043546)
2.2	15.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
2.2	6.6	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
2.2	67.7	GO:0017075	syntaxin-1 binding(GO:0017075)
2.2	13.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
2.2	19.4	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
2.1	25.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
2.1	29.4	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
2.1	25.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
2.1	14.4	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
2.1	10.3	GO:0001888	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
2.1	12.3	GO:0016929	SUMO-specific protease activity(GO:0016929)
2.0	8.1	GO:0001626	nociceptin receptor activity(GO:0001626)
2.0	29.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
2.0	12.0	GO:0016361	activin receptor activity, type I(GO:0016361)
2.0	13.8	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
1.9	27.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
1.9	17.3	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
1.9	9.6	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
1.9	17.2	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
1.9	26.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
1.9	24.5	GO:0031681	G-protein beta-subunit binding(GO:0031681)
1.9	31.6	GO:0003680	AT DNA binding(GO:0003680)
1.8	5.5	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.8	47.4	GO:0031489	myosin V binding(GO:0031489)
1.8	12.7	GO:0001515	opioid peptide activity(GO:0001515)
1.8	7.0	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.7	25.8	GO:0005344	oxygen transporter activity(GO:0005344)
1.7	5.1	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
1.7	45.4	GO:0048156	tau protein binding(GO:0048156)
1.6	50.9	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.6	7.9	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
1.5	7.7	GO:0004803	transposase activity(GO:0004803)
1.5	5.8	GO:0086077	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.3	2.7	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
1.3	12.8	GO:0051011	microtubule minus-end binding(GO:0051011)
1.2	2.4	GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
1.2	4.6	GO:0016972	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
1.1	4.6	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.1	3.3	GO:0070984	SET domain binding(GO:0070984)
1.1	3.3	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
1.1	5.6	GO:0004370	glycerol kinase activity(GO:0004370)
1.1	19.6	GO:0008432	JUN kinase binding(GO:0008432)
1.1	3.2	GO:0052725	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
1.1	5.3	GO:0048763	calcium-induced calcium release activity(GO:0048763)
1.0	3.1	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.0	5.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
1.0	20.4	GO:0097109	neuroligin family protein binding(GO:0097109)
1.0	8.1	GO:0008430	selenium binding(GO:0008430)
1.0	10.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
1.0	9.0	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.0	8.9	GO:0048495	Roundabout binding(GO:0048495)
1.0	24.8	GO:0050780	dopamine receptor binding(GO:0050780)
0.9	0.9	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.9	19.7	GO:0015929	hexosaminidase activity(GO:0015929)
0.9	2.8	GO:0032093	SAM domain binding(GO:0032093)
0.9	2.8	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.9	4.5	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.9	2.7	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.9	17.0	GO:0031005	filamin binding(GO:0031005)
0.9	4.5	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.9	5.3	GO:0016807	cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.9	43.5	GO:0042169	SH2 domain binding(GO:0042169)
0.9	2.7	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.9	39.9	GO:0019894	kinesin binding(GO:0019894)
0.9	3.4	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.9	10.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.8	66.8	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.8	2.5	GO:0060001	minus-end directed microfilament motor activity(GO:0060001)
0.8	10.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.8	4.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.8	16.3	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.8	15.4	GO:0097602	cullin family protein binding(GO:0097602)
0.8	3.9	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8	3.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.7	2.2	GO:0001003	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.7	20.7	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.7	14.6	GO:0005522	profilin binding(GO:0005522)
0.7	2.1	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.7	2.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.7	14.7	GO:0005112	Notch binding(GO:0005112)
0.7	4.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.7	27.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.7	4.8	GO:0008172	S-methyltransferase activity(GO:0008172)
0.7	4.1	GO:0004882	androgen receptor activity(GO:0004882)
0.7	17.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.7	3.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.6	2.6	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.6	3.8	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.6	6.9	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.6	5.0	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.6	4.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.6	2.5	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.6	12.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.6	10.4	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.6	4.2	GO:0051525	NFAT protein binding(GO:0051525)
0.6	27.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.6	5.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.6	4.1	GO:0004985	opioid receptor activity(GO:0004985)
0.6	9.9	GO:0008327	methyl-CpG binding(GO:0008327)
0.6	6.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.6	14.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.5	3.2	GO:0039552	RIG-I binding(GO:0039552)
0.5	37.9	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.5	3.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.5	21.3	GO:0005158	insulin receptor binding(GO:0005158)
0.5	4.4	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.5	27.9	GO:0017080	sodium channel regulator activity(GO:0017080)
0.5	1.4	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.5	15.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5	2.3	GO:0005298	proline:sodium symporter activity(GO:0005298)
0.5	1.8	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.4	1.8	GO:0035939	microsatellite binding(GO:0035939)
0.4	4.8	GO:0017154	semaphorin receptor activity(GO:0017154)
0.4	3.1	GO:0005499	vitamin D binding(GO:0005499)
0.4	1.3	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.4	18.0	GO:0030332	cyclin binding(GO:0030332)
0.4	9.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.4	2.5	GO:0009378	four-way junction helicase activity(GO:0009378)
0.4	5.7	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.4	74.4	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.4	16.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4	12.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.4	2.2	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.4	5.6	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.4	18.2	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.4	5.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.4	4.6	GO:0070700	BMP receptor binding(GO:0070700)
0.3	2.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.3	0.7	GO:0009931	calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3	2.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.3	1.7	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.3	24.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3	9.0	GO:0071837	HMG box domain binding(GO:0071837)
0.3	54.6	GO:0017137	Rab GTPase binding(GO:0017137)
0.3	8.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.3	2.6	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3	3.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.3	3.9	GO:0048185	activin binding(GO:0048185)
0.3	1.6	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3	4.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.3	1.9	GO:0005534	galactose binding(GO:0005534)
0.3	1.9	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3	2.8	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.3	2.5	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.3	5.5	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.3	3.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3	2.7	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.3	9.3	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.3	3.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.3	2.8	GO:0004707	MAP kinase activity(GO:0004707)
0.3	1.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3	2.5	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.3	11.4	GO:0005246	calcium channel regulator activity(GO:0005246)
0.3	3.7	GO:0042043	neurexin family protein binding(GO:0042043)
0.3	2.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.3	10.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3	15.8	GO:0030276	clathrin binding(GO:0030276)
0.3	4.6	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2	2.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.2	7.8	GO:0005249	voltage-gated potassium channel activity(GO:0005249) potassium channel activity(GO:0005267)
0.2	6.5	GO:0005521	lamin binding(GO:0005521)
0.2	7.9	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.2	3.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.2	2.2	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.2	12.8	GO:0070412	R-SMAD binding(GO:0070412)
0.2	3.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.2	1.0	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.2	2.7	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.2	3.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.2	4.2	GO:0032183	SUMO binding(GO:0032183)
0.2	5.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.2	3.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.2	18.2	GO:0016209	antioxidant activity(GO:0016209)
0.2	1.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.2	2.7	GO:0042577	lipid phosphatase activity(GO:0042577)
0.2	0.9	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2	8.6	GO:0003777	microtubule motor activity(GO:0003777)
0.2	2.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2	1.6	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609) adenosine receptor binding(GO:0031685)
0.2	5.9	GO:0043236	laminin binding(GO:0043236)
0.2	0.9	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.2	13.1	GO:0016782	transferase activity, transferring sulfur-containing groups(GO:0016782)
0.2	4.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.2	5.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.2	4.4	GO:1902936	phosphatidylinositol bisphosphate binding(GO:1902936)
0.1	5.4	GO:0051393	alpha-actinin binding(GO:0051393)
0.1	3.6	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	1.6	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	17.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	2.2	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.1	39.0	GO:0030695	GTPase regulator activity(GO:0030695)
0.1	1.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	2.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	1.7	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	6.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	68.4	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.1	4.2	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.1	5.1	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	0.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	29.1	GO:0008022	protein C-terminus binding(GO:0008022)
0.1	1.8	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	4.8	GO:0016247	channel regulator activity(GO:0016247)
0.1	6.9	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1	2.9	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	2.3	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1	12.8	GO:0005516	calmodulin binding(GO:0005516)
0.1	22.1	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1	1.6	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.1	10.4	GO:0044325	ion channel binding(GO:0044325)
0.1	3.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	0.7	GO:0016015	morphogen activity(GO:0016015)
0.1	0.3	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.1	1.9	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	3.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.9	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.1	2.7	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.1	15.9	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.1	2.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	0.7	GO:0030955	potassium ion binding(GO:0030955)
0.1	3.9	GO:0005507	copper ion binding(GO:0005507)
0.1	1.3	GO:0001223	transcription coactivator binding(GO:0001223)
0.1	0.6	GO:0004000	adenosine deaminase activity(GO:0004000)
0.1	1.2	GO:0016805	dipeptidase activity(GO:0016805)
0.1	39.8	GO:0008270	zinc ion binding(GO:0008270)
0.1	0.3	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	4.6	GO:0001618	virus receptor activity(GO:0001618)
0.1	0.3	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.4	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.3	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.0	2.0	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.6	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	133.7	PID RAS PATHWAY	Regulation of Ras family activation
2.5	49.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
1.5	33.9	PID LPA4 PATHWAY	LPA4-mediated signaling events
1.4	11.6	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
1.2	67.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
1.1	63.6	PID RHOA PATHWAY	RhoA signaling pathway
1.0	57.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
1.0	29.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.9	25.7	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.9	6.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.9	38.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.8	13.6	PID EPHA FWDPATHWAY	EPHA forward signaling
0.7	24.6	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.6	32.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.6	17.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.6	14.1	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.5	5.4	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.5	15.9	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.4	13.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.4	26.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.4	12.3	PID REELIN PATHWAY	Reelin signaling pathway
0.4	12.6	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.4	2.7	PID S1P S1P2 PATHWAY	S1P2 pathway
0.4	13.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.3	31.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.3	10.9	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.3	4.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.3	15.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.3	12.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	58.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	3.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	0.8	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	8.9	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.2	8.7	PID MTOR 4PATHWAY	mTOR signaling pathway
0.2	4.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.2	7.0	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	12.7	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	0.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.9	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	5.1	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	2.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	4.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	30.0	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	2.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	4.9	PID LKB1 PATHWAY	LKB1 signaling events
0.1	2.3	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	3.9	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	1.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	2.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	4.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	1.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	0.7	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	1.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.7	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	1.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.4	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.4	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	2.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.1	195.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
3.4	24.0	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
2.2	47.9	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.8	5.3	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
1.7	22.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
1.7	56.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.5	38.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
1.5	11.7	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
1.4	11.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
1.3	11.8	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
1.3	16.9	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
1.3	26.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.1	39.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
1.1	54.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
1.0	7.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
1.0	19.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
1.0	35.6	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
1.0	18.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.9	17.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.8	16.9	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.8	1.6	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.7	30.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.7	19.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.7	16.6	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.7	21.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.7	11.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.7	17.8	REACTOME KINESINS	Genes involved in Kinesins
0.6	14.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.6	32.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.6	12.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.6	10.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.6	13.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.5	6.5	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.5	15.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.5	19.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.4	5.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.4	18.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.4	3.8	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.4	3.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.4	0.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.4	19.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.3	21.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	5.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.3	7.1	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.3	2.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	12.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	4.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.3	5.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.3	3.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.3	7.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.3	14.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.3	5.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	14.7	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.2	7.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2	47.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.2	3.3	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.2	3.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	4.5	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.2	25.9	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.2	2.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	5.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.2	6.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	21.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.2	3.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.2	7.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	2.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	4.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	5.1	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.1	5.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	1.9	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	10.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	3.0	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	2.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	7.2	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	6.4	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.1	2.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	2.0	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.1	2.4	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	0.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	3.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.8	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	15.2	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.1	5.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	1.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.9	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	6.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	1.7	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	3.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.5	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	1.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling

Results for ZBTB14

Z-value: 1.90

Motif logo

Transcription factors associated with ZBTB14

Activity-expression correlation:

Activity profile of ZBTB14 motif

Sorted Z-values of ZBTB14 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB14

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: