Project
GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for ZBTB7A_ZBTB7C
Z-value: 1.08
Motif logo
Transcription factors associated with ZBTB7A_ZBTB7C
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZBTB7A | hg38_v1_chr19_-_4066892_4066906 | 0.35 | 1.6e-07 | Click! |
| ZBTB7C | hg38_v1_chr18_-_48409292_48409401, hg38_v1_chr18_-_48137295_48137361 | 0.01 | 8.4e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZBTB7A_ZBTB7C
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 47.1 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 38.8 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 6.8 | 33.9 | GO:1902613 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 8.9 | 26.6 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288) |
| 0.5 | 22.0 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 3.8 | 19.0 | GO:0030309 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 3.7 | 18.4 | GO:0007412 | axon target recognition(GO:0007412) |
| 4.1 | 16.4 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.1 | 14.7 | GO:0046330 | positive regulation of JNK cascade(GO:0046330) |
| 2.4 | 14.4 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.6 | 61.1 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 1.5 | 26.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.3 | 26.4 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.5 | 19.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.6 | 18.7 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.3 | 18.4 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.8 | 14.0 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.5 | 12.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 2.3 | 11.7 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 9.4 | GO:0005923 | bicellular tight junction(GO:0005923) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 47.1 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 2.0 | 26.6 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.5 | 22.0 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 3.8 | 19.0 | GO:0008532 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) |
| 3.1 | 18.4 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.0 | 16.0 | GO:0005509 | calcium ion binding(GO:0005509) |
| 2.9 | 14.4 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 0.1 | 13.6 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.4 | 12.3 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.1 | 11.5 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 31.7 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.2 | 14.3 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.4 | 7.0 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 6.7 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.2 | 6.1 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 5.1 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 4.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 3.4 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 2.9 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.2 | 2.3 | PID S1P S1P2 PATHWAY | S1P2 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 28.5 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 19.0 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.1 | 16.1 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.2 | 14.3 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 1.1 | 13.0 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.3 | 13.0 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.3 | 12.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 9.4 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 9.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 7.1 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |