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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ZNF691

Z-value: 0.54

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Transcription factors associated with ZNF691

Gene Symbol Gene ID Gene Info
ZNF691
ENSG00000164011.18 ZNF691

Activity profile of ZNF691 motif

Sorted Z-values of ZNF691 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF691

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_26317950 10.47 ENST00000374213.3
CD52
CD52 molecule
chr12_-_51324091 8.30 ENST00000604560.6
BIN2
bridging integrator 2
chr12_-_51324164 7.26 ENST00000615107.6
BIN2
bridging integrator 2
chr12_-_51324138 7.24 ENST00000452142.7
BIN2
bridging integrator 2
chr1_+_27872536 6.57 ENST00000328928.11
ENST00000373921.8
ENST00000373925.5
ENST00000373927.7
ENST00000427466.1
ENST00000442118.5
THEMIS2
thymocyte selection associated family member 2
chr12_-_51324652 6.56 ENST00000544402.5
BIN2
bridging integrator 2
chr17_+_82458733 4.89 ENST00000309794.16
ENST00000577410.2
NARF
nuclear prelamin A recognition factor
chr6_+_31586269 4.76 ENST00000438075.7
LST1
leukocyte specific transcript 1
chr2_+_68734773 4.55 ENST00000409202.8
ARHGAP25
Rho GTPase activating protein 25
chrX_+_103215072 4.52 ENST00000372695.6
ENST00000372691.3
BEX4
brain expressed X-linked 4
chr11_+_121590388 4.49 ENST00000527934.1
SORL1
sortilin related receptor 1
chr3_+_46370854 3.87 ENST00000292303.4
CCR5
C-C motif chemokine receptor 5
chr2_+_68734861 3.68 ENST00000467265.5
ARHGAP25
Rho GTPase activating protein 25
chr6_+_31586124 3.52 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
LST1
leukocyte specific transcript 1
chr17_+_82458649 3.25 ENST00000345415.11
ENST00000412079.6
ENST00000457415.7
ENST00000584411.5
ENST00000577432.5
NARF
nuclear prelamin A recognition factor
chr3_-_172523460 3.09 ENST00000420541.6
TNFSF10
TNF superfamily member 10
chr17_+_82458174 3.06 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
NARF
nuclear prelamin A recognition factor
chr14_-_20802836 2.94 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
RNASE1
ribonuclease A family member 1, pancreatic
chr10_+_127907036 2.92 ENST00000254667.8
ENST00000442830.5
PTPRE
protein tyrosine phosphatase receptor type E
chr20_-_1657762 2.90 ENST00000303415.7
ENST00000381583.6
SIRPG
signal regulatory protein gamma
chr16_+_84294823 2.89 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr22_-_31662180 2.86 ENST00000435900.5
PISD
phosphatidylserine decarboxylase
chr14_-_20802402 2.80 ENST00000412779.2
RNASE1
ribonuclease A family member 1, pancreatic
chr17_+_75610690 2.76 ENST00000642007.1
MYO15B
myosin XVB
chr16_+_84294853 2.76 ENST00000219454.10
WFDC1
WAP four-disulfide core domain 1
chr2_+_201233443 2.52 ENST00000392263.6
ENST00000264274.13
ENST00000432109.6
ENST00000264275.9
ENST00000450491.5
ENST00000440732.5
ENST00000392258.7
CASP8
caspase 8
chr20_+_64255728 2.51 ENST00000369758.8
ENST00000308824.11
ENST00000609372.1
ENST00000610196.1
ENST00000609764.1
PCMTD2
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr15_-_58279245 2.44 ENST00000558231.5
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr6_-_89819699 2.41 ENST00000439638.1
ENST00000629399.2
ENST00000369393.8
MDN1
midasin AAA ATPase 1
chr19_-_17821505 2.34 ENST00000598577.1
ENST00000317306.8
ENST00000379695.5
INSL3
insulin like 3
chr3_-_172523423 2.25 ENST00000241261.7
TNFSF10
TNF superfamily member 10
chr17_+_47209035 2.20 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
MYL4
myosin light chain 4
chr12_-_10453330 2.13 ENST00000347831.9
ENST00000359151.8
KLRC1
killer cell lectin like receptor C1
chr2_+_201260496 2.12 ENST00000323492.11
CASP8
caspase 8
chr4_-_82798735 1.93 ENST00000273908.4
ENST00000319540.9
SCD5
stearoyl-CoA desaturase 5
chr16_+_85654386 1.84 ENST00000412692.5
GSE1
Gse1 coiled-coil protein
chr5_-_132556809 1.83 ENST00000450655.1
IL5
interleukin 5
chr12_-_132687307 1.81 ENST00000535270.5
ENST00000320574.10
POLE
DNA polymerase epsilon, catalytic subunit
chr9_-_120929160 1.71 ENST00000540010.1
TRAF1
TNF receptor associated factor 1
chr6_-_144008364 1.61 ENST00000625622.2
PLAGL1
PLAG1 like zinc finger 1
chr2_+_105851748 1.58 ENST00000425756.1
ENST00000393349.2
NCK2
NCK adaptor protein 2
chr9_+_132878873 1.47 ENST00000356311.10
ENST00000350499.6
SPACA9
sperm acrosome associated 9
chr3_+_44555185 1.44 ENST00000426540.6
ENST00000431636.5
ENST00000341840.7
ENST00000273320.7
ZKSCAN7
zinc finger with KRAB and SCAN domains 7
chr5_-_132011794 1.41 ENST00000650697.1
ACSL6
acyl-CoA synthetase long chain family member 6
chr6_-_144008396 1.31 ENST00000354765.6
ENST00000416623.5
ENST00000649211.1
PLAGL1
PLAG1 like zinc finger 1
chr19_+_49581304 1.28 ENST00000246794.10
PRRG2
proline rich and Gla domain 2
chr19_+_49877660 1.21 ENST00000535102.6
TBC1D17
TBC1 domain family member 17
chr16_+_56336805 1.17 ENST00000564727.2
GNAO1
G protein subunit alpha o1
chr11_-_65122057 1.12 ENST00000531743.5
ENST00000527548.5
ENST00000526555.5
ENST00000529639.6
ENST00000279259.7
FAU
FAU ubiquitin like and ribosomal protein S30 fusion
chr19_-_49808639 1.10 ENST00000529634.2
FUZ
fuzzy planar cell polarity protein
chr10_-_97498378 1.10 ENST00000327238.14
ENST00000437002.5
ENST00000438925.7
ENST00000422685.5
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component
chr14_+_49893055 1.06 ENST00000298316.7
ARF6
ADP ribosylation factor 6
chr17_-_63931354 1.05 ENST00000647774.1
ENSG00000285947.1
novel protein
chr3_-_45995807 1.04 ENST00000535325.5
ENST00000296137.7
FYCO1
FYVE and coiled-coil domain autophagy adaptor 1
chr1_+_203765168 1.01 ENST00000367217.5
ENST00000442561.7
LAX1
lymphocyte transmembrane adaptor 1
chr12_+_100503352 0.99 ENST00000551379.5
ENST00000188403.7
NR1H4
nuclear receptor subfamily 1 group H member 4
chr13_-_52129051 0.99 ENST00000652119.1
ENST00000647945.1
ENST00000355568.8
NEK5
NIMA related kinase 5
chr16_+_56336767 0.93 ENST00000640469.1
GNAO1
G protein subunit alpha o1
chr5_-_132011811 0.92 ENST00000379255.5
ENST00000430403.5
ENST00000357096.5
ACSL6
acyl-CoA synthetase long chain family member 6
chr8_-_144103678 0.87 ENST00000398712.7
SHARPIN
SHANK associated RH domain interactor
chr16_+_56336727 0.85 ENST00000568375.2
GNAO1
G protein subunit alpha o1
chr6_-_27312258 0.84 ENST00000444565.2
POM121L2
POM121 transmembrane nucleoporin like 2
chr11_-_57381146 0.83 ENST00000287143.2
PRG3
proteoglycan 3, pro eosinophil major basic protein 2
chr11_+_60455839 0.83 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
MS4A1
membrane spanning 4-domains A1
chr5_-_179618032 0.81 ENST00000519033.5
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1
chr2_-_202871747 0.76 ENST00000358299.7
ICA1L
islet cell autoantigen 1 like
chr5_-_179617581 0.76 ENST00000523449.5
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1
chr12_-_23584600 0.74 ENST00000396007.6
SOX5
SRY-box transcription factor 5
chr12_+_94262521 0.72 ENST00000545312.1
PLXNC1
plexin C1
chr20_-_23688951 0.72 ENST00000217423.4
CST4
cystatin S
chr8_+_141416078 0.72 ENST00000349124.3
PTP4A3
protein tyrosine phosphatase 4A3
chr8_+_141416141 0.72 ENST00000680615.1
PTP4A3
protein tyrosine phosphatase 4A3
chr9_+_132978687 0.71 ENST00000372122.4
ENST00000372123.5
GFI1B
growth factor independent 1B transcriptional repressor
chr1_-_203086001 0.70 ENST00000241651.5
MYOG
myogenin
chr3_-_49869886 0.70 ENST00000296471.11
ENST00000488336.5
ENST00000477224.6
ENST00000467248.5
ENST00000466940.5
ENST00000463537.5
ENST00000480398.2
CAMKV
CaM kinase like vesicle associated
chr2_-_127642131 0.68 ENST00000426981.5
LIMS2
LIM zinc finger domain containing 2
chr20_+_38304149 0.66 ENST00000262865.9
ENST00000642449.2
BPI
bactericidal permeability increasing protein
chr15_-_82349437 0.64 ENST00000621197.4
ENST00000610657.2
ENST00000619556.4
GOLGA6L10
golgin A6 family like 10
chr20_-_23750929 0.64 ENST00000304749.7
CST1
cystatin SN
chr10_-_89251768 0.64 ENST00000336233.10
LIPA
lipase A, lysosomal acid type
chr15_-_74433942 0.63 ENST00000543145.6
ENST00000261918.9
SEMA7A
semaphorin 7A (John Milton Hagen blood group)
chr2_-_85668172 0.60 ENST00000428225.5
ENST00000519937.7
SFTPB
surfactant protein B
chr1_-_233295712 0.58 ENST00000258229.14
PCNX2
pecanex 2
chr2_-_202871611 0.56 ENST00000392237.6
ENST00000416760.5
ENST00000412210.5
ICA1L
islet cell autoantigen 1 like
chrX_+_153517626 0.55 ENST00000263519.5
ATP2B3
ATPase plasma membrane Ca2+ transporting 3
chr10_+_102918276 0.54 ENST00000369878.9
ENST00000369875.3
CNNM2
cyclin and CBS domain divalent metal cation transport mediator 2
chr16_+_31214111 0.54 ENST00000322122.8
TRIM72
tripartite motif containing 72
chr2_-_219243577 0.53 ENST00000409640.5
GLB1L
galactosidase beta 1 like
chr3_+_129974680 0.53 ENST00000507066.1
TRH
thyrotropin releasing hormone
chr18_+_11751494 0.52 ENST00000269162.9
GNAL
G protein subunit alpha L
chr16_+_78099400 0.50 ENST00000627394.3
WWOX
WW domain containing oxidoreductase
chr10_+_102918344 0.48 ENST00000433628.2
CNNM2
cyclin and CBS domain divalent metal cation transport mediator 2
chr17_+_81528370 0.46 ENST00000417245.7
ENST00000334850.7
FSCN2
fascin actin-bundling protein 2, retinal
chr4_+_663696 0.45 ENST00000471824.6
PDE6B
phosphodiesterase 6B
chr3_+_129974712 0.42 ENST00000302649.4
TRH
thyrotropin releasing hormone
chrX_+_153517672 0.42 ENST00000349466.6
ENST00000370186.5
ENST00000359149.8
ATP2B3
ATPase plasma membrane Ca2+ transporting 3
chr6_-_158819355 0.40 ENST00000367075.4
EZR
ezrin
chr11_-_3671367 0.38 ENST00000534359.1
ENST00000250699.2
CHRNA10
cholinergic receptor nicotinic alpha 10 subunit
chr1_-_16437416 0.37 ENST00000375577.5
ENST00000335496.5
SPATA21
spermatogenesis associated 21
chr11_-_36598221 0.31 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
RAG2
recombination activating 2
chr17_+_32444379 0.24 ENST00000578213.5
ENST00000649012.1
ENST00000457654.6
ENST00000579451.1
ENST00000261712.8
PSMD11
proteasome 26S subunit, non-ATPase 11
chr19_+_12751789 0.23 ENST00000553030.6
BEST2
bestrophin 2
chr12_+_53461015 0.22 ENST00000553064.6
ENST00000547859.2
PCBP2
poly(rC) binding protein 2
chr21_-_36480060 0.22 ENST00000399137.5
CLDN14
claudin 14
chr20_-_35147285 0.21 ENST00000374491.3
ENST00000374492.8
EDEM2
ER degradation enhancing alpha-mannosidase like protein 2
chr9_+_135561749 0.19 ENST00000479141.6
ENST00000611414.4
ENST00000371766.6
ENST00000277508.9
ENST00000433563.5
PAEP
progestagen associated endometrial protein
chr20_-_2664186 0.18 ENST00000474315.5
ENST00000380843.9
ENST00000380851.9
ENST00000613370.1
IDH3B
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
chr17_+_38752731 0.18 ENST00000619426.5
ENST00000610434.4
PSMB3
proteasome 20S subunit beta 3
chr20_-_2508888 0.18 ENST00000421216.1
ENST00000278772.9
ENST00000381253.5
ZNF343
zinc finger protein 343
chr16_+_57628507 0.12 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
ADGRG1
adhesion G protein-coupled receptor G1
chr19_+_58544447 0.11 ENST00000594806.5
ENST00000341753.10
TRIM28
tripartite motif containing 28
chr9_+_132978651 0.09 ENST00000636137.1
GFI1B
growth factor independent 1B transcriptional repressor
chr16_-_53703883 0.09 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1L
RPGRIP1 like
chr21_-_36480117 0.07 ENST00000399135.6
CLDN14
claudin 14
chr6_-_119149124 0.04 ENST00000368475.8
FAM184A
family with sequence similarity 184 member A
chr4_+_157076119 0.03 ENST00000541722.5
ENST00000264428.9
ENST00000512619.5
GLRB
glycine receptor beta
chr9_+_113505256 0.03 ENST00000374136.5
RGS3
regulator of G protein signaling 3
chr19_-_45973986 0.01 ENST00000676183.1
NOVA2
NOVA alternative splicing regulator 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.3 29.4 GO:0097320 membrane tubulation(GO:0097320)
1.2 4.6 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.6 1.8 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.5 1.8 GO:0006272 leading strand elongation(GO:0006272)
0.4 3.9 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 1.8 GO:0001692 histamine metabolic process(GO:0001692)
0.3 1.1 GO:0090299 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.3 2.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 1.6 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.3 10.5 GO:0045730 respiratory burst(GO:0045730)
0.3 5.3 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.2 1.0 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 0.7 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2 1.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 1.0 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.7 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 1.5 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.9 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 1.4 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.3 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.1 4.3 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.1 5.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 8.3 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1 0.2 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.1 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 3.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 2.9 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 2.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.1 GO:1901536 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 5.6 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 0.7 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 2.2 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 2.3 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.6 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 1.0 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 2.9 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 7.0 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.7 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.8 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.6 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 2.9 GO:0050870 positive regulation of T cell activation(GO:0050870)
0.0 1.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.8 GO:0042100 B cell proliferation(GO:0042100)
0.0 2.5 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 1.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.7 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.0 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 1.3 GO:0007286 spermatid development(GO:0007286)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 29.4 GO:0001891 phagocytic cup(GO:0001891)
1.0 11.2 GO:0005638 lamin filament(GO:0005638)
0.4 1.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 1.1 GO:0071817 MMXD complex(GO:0071817)
0.2 4.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 4.6 GO:0097342 ripoptosome(GO:0097342)
0.1 0.9 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.4 GO:0044393 microspike(GO:0044393)
0.1 1.1 GO:0090543 Flemming body(GO:0090543)
0.1 2.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 10.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 3.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.6 GO:0016459 myosin complex(GO:0016459)
0.0 1.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 1.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 4.0 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.8 4.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.7 2.9 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.6 1.8 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.5 2.5 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.5 1.9 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.4 2.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.4 11.2 GO:0005521 lamin binding(GO:0005521)
0.4 2.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.3 1.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 4.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 3.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 1.0 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 2.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 2.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 1.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.2 7.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.1 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.6 GO:0004771 sterol esterase activity(GO:0004771)
0.1 2.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 2.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 30.2 GO:0005543 phospholipid binding(GO:0005543)
0.1 5.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0023026 MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 9.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 2.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.6 GO:0003774 motor activity(GO:0003774)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 2.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 3.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 2.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 10.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.8 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 2.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 8.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 3.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling